LOCUS       DAVAZV010000001        83356 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVAZV010000001 DAVAZV010000000
VERSION     DAVAZV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 83356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83356
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.001"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..183
                     /locus_tag="VQT46_000001"
     CDS             <1..183
                     /locus_tag="VQT46_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2370117.1"
                     /translation="LTVEDKAYNHALSKERSKVENIFAKVKTFKMFSTTYRNHRKRFG
                     LRMNLIAGIINHELGF"
     gene            251..499
                     /locus_tag="VQT46_000002"
     CDS             251..499
                     /locus_tag="VQT46_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370118.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRIYSGNLILQELITVNGAYKATYIGELSSN"
     gene            630..1802
                     /locus_tag="VQT46_000003"
     CDS             630..1802
                     /locus_tag="VQT46_000003"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET2370119.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENADSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            1802..3076
                     /locus_tag="VQT46_000004"
     CDS             1802..3076
                     /locus_tag="VQT46_000004"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET2370120.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLEFANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLIGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VAFSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(3112..4077)
                     /locus_tag="VQT46_000005"
     CDS             complement(3112..4077)
                     /locus_tag="VQT46_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2370121.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQTIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(4058..5512)
                     /locus_tag="VQT46_000006"
     CDS             complement(4058..5512)
                     /locus_tag="VQT46_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2370122.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKSQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEHPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            5889..7772
                     /locus_tag="VQT46_000007"
     CDS             5889..7772
                     /locus_tag="VQT46_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2370123.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYALADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVSKGDAVIE
                     VKI"
     gene            7921..8808
                     /locus_tag="VQT46_000008"
     CDS             7921..8808
                     /locus_tag="VQT46_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2370124.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGTSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(9128..9745)
                     /locus_tag="VQT46_000009"
     CDS             complement(9128..9745)
                     /locus_tag="VQT46_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET2370125.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(10160..10348)
                     /locus_tag="VQT46_000010"
                     /pseudo
     CDS             complement(10160..10348)
                     /locus_tag="VQT46_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(10858..10938)
                     /locus_tag="VQT46_000011"
                     /pseudo
     CDS             complement(10858..10938)
                     /locus_tag="VQT46_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            11054..11947
                     /locus_tag="VQT46_000012"
     CDS             11054..11947
                     /locus_tag="VQT46_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370126.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            11944..13143
                     /locus_tag="VQT46_000013"
     CDS             11944..13143
                     /locus_tag="VQT46_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370127.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLEQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINGYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(13496..14263)
                     /locus_tag="VQT46_000014"
     CDS             complement(13496..14263)
                     /locus_tag="VQT46_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370128.1"
                     /translation="MFWNLVHYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(14280..14975)
                     /locus_tag="VQT46_000015"
     CDS             complement(14280..14975)
                     /locus_tag="VQT46_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370129.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(14980..15345)
                     /locus_tag="VQT46_000016"
     CDS             complement(14980..15345)
                     /locus_tag="VQT46_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2370130.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMIH
                     FGYEKEELPGVVSDYIKGV"
     gene            15485..15958
                     /gene="nrdR"
                     /locus_tag="VQT46_000017"
     CDS             15485..15958
                     /gene="nrdR"
                     /locus_tag="VQT46_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET2370131.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            15959..17128
                     /locus_tag="VQT46_000018"
     CDS             15959..17128
                     /locus_tag="VQT46_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET2370132.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFNPKEATIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKTKTQKQNQTAPAKTNIPKWSNPDYKNETSEETRLELERKKQELLARLEKGGD"
     gene            17129..18025
                     /gene="dnaI"
                     /locus_tag="VQT46_000019"
     CDS             17129..18025
                     /gene="dnaI"
                     /locus_tag="VQT46_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET2370133.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            18022..18735
                     /locus_tag="VQT46_000020"
     CDS             18022..18735
                     /locus_tag="VQT46_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HET2370134.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            18749..20059
                     /gene="der"
                     /locus_tag="VQT46_000021"
     CDS             18749..20059
                     /gene="der"
                     /locus_tag="VQT46_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET2370135.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            20150..20485
                     /locus_tag="VQT46_000022"
     CDS             20150..20485
                     /locus_tag="VQT46_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370136.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            20625..20960
                     /locus_tag="VQT46_000023"
     CDS             20625..20960
                     /locus_tag="VQT46_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370137.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            21145..21936
                     /locus_tag="VQT46_000024"
     CDS             21145..21936
                     /locus_tag="VQT46_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370138.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            21929..22570
                     /locus_tag="VQT46_000025"
     CDS             21929..22570
                     /locus_tag="VQT46_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370139.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLIVSRLEEKFKKG"
     gene            22574..23224
                     /locus_tag="VQT46_000026"
     CDS             22574..23224
                     /locus_tag="VQT46_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2370140.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            23235..23522
                     /locus_tag="VQT46_000027"
     CDS             23235..23522
                     /locus_tag="VQT46_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370141.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     MQKILLAFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            23668..26181
                     /gene="secA"
                     /locus_tag="VQT46_000028"
     CDS             23668..26181
                     /gene="secA"
                     /locus_tag="VQT46_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET2370142.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMATLTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQAMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            26262..27293
                     /locus_tag="VQT46_000029"
     CDS             26262..27293
                     /locus_tag="VQT46_000029"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2370143.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            27295..28326
                     /locus_tag="VQT46_000030"
     CDS             27295..28326
                     /locus_tag="VQT46_000030"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET2370144.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            28365..28733
                     /locus_tag="VQT46_000031"
     CDS             28365..28733
                     /locus_tag="VQT46_000031"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET2370145.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            28723..29826
                     /locus_tag="VQT46_000032"
     CDS             28723..29826
                     /locus_tag="VQT46_000032"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET2370146.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLALPYDLIPALTLESALVHIKTVPAGACMGYGATYQTDSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            29845..31860
                     /gene="recG"
                     /locus_tag="VQT46_000033"
     CDS             29845..31860
                     /gene="recG"
                     /locus_tag="VQT46_000033"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET2370147.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     IKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            32176..33156
                     /locus_tag="VQT46_000034"
     CDS             32176..33156
                     /locus_tag="VQT46_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET2370148.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVNDQVYNWLCGSEIPFKYLK"
     gene            33961..34188
                     /locus_tag="VQT46_000035"
     CDS             33961..34188
                     /locus_tag="VQT46_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370149.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            34476..37373
                     /gene="nanA"
                     /locus_tag="VQT46_000036"
     CDS             34476..37373
                     /gene="nanA"
                     /locus_tag="VQT46_000036"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET2370150.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALTPEEVQKRSQLFKRSDLEKKLPEGAALTEKTDIFESGRNGKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGNRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGNQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHNGKEYIILSNAGGPNRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKDLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            38388..38840
                     /locus_tag="VQT46_000037"
     CDS             38388..38840
                     /locus_tag="VQT46_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2370151.1"
                     /translation="MIITKISHLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVQLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            38859..40196
                     /locus_tag="VQT46_000038"
     CDS             38859..40196
                     /locus_tag="VQT46_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2370152.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            40275..41159
                     /locus_tag="VQT46_000039"
     CDS             40275..41159
                     /locus_tag="VQT46_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2370153.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            41159..41992
                     /locus_tag="VQT46_000040"
     CDS             41159..41992
                     /locus_tag="VQT46_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2370154.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            42010..44103
                     /gene="nanB"
                     /locus_tag="VQT46_000041"
     CDS             42010..44103
                     /gene="nanB"
                     /locus_tag="VQT46_000041"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET2370155.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISPLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKRSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNREESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            44115..45218
                     /locus_tag="VQT46_000042"
     CDS             44115..45218
                     /locus_tag="VQT46_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2370156.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            45392..46090
                     /locus_tag="VQT46_000043"
     CDS             45392..46090
                     /locus_tag="VQT46_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2370157.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            46109..47626
                     /locus_tag="VQT46_000044"
     CDS             46109..47626
                     /locus_tag="VQT46_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2370158.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADLAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFLGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPFGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            47751..49079
                     /locus_tag="VQT46_000045"
     CDS             47751..49079
                     /locus_tag="VQT46_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370159.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            49331..50197
                     /locus_tag="VQT46_000046"
     CDS             49331..50197
                     /locus_tag="VQT46_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2370160.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            50213..51052
                     /locus_tag="VQT46_000047"
     CDS             50213..51052
                     /locus_tag="VQT46_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2370161.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            51325..51777
                     /locus_tag="VQT46_000048"
     CDS             51325..51777
                     /locus_tag="VQT46_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2370162.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLIEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            51874..52218
                     /locus_tag="VQT46_000049"
     CDS             51874..52218
                     /locus_tag="VQT46_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370163.1"
                     /translation="MVSSKHAARASFLDGQEITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGIGIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            52502..53146
                     /locus_tag="VQT46_000050"
     CDS             52502..53146
                     /locus_tag="VQT46_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2370164.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            53315..54232
                     /locus_tag="VQT46_000051"
     CDS             53315..54232
                     /locus_tag="VQT46_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET2370165.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTATHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKESFL"
     gene            54250..55134
                     /locus_tag="VQT46_000052"
     CDS             54250..55134
                     /locus_tag="VQT46_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2370166.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(55150..56001)
                     /locus_tag="VQT46_000053"
     CDS             complement(55150..56001)
                     /locus_tag="VQT46_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2370167.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANRVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            56201..58258
                     /gene="pbp2b"
                     /locus_tag="VQT46_000054"
     CDS             56201..58258
                     /gene="pbp2b"
                     /locus_tag="VQT46_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET2370168.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTKRQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGD
                     LIQQLQPTEINKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            58269..58865
                     /gene="recR"
                     /locus_tag="VQT46_000055"
     CDS             58269..58865
                     /gene="recR"
                     /locus_tag="VQT46_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET2370169.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            59041..60084
                     /locus_tag="VQT46_000056"
     CDS             59041..60084
                     /locus_tag="VQT46_000056"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET2370170.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            60168..61541
                     /locus_tag="VQT46_000057"
     CDS             60168..61541
                     /locus_tag="VQT46_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET2370171.1"
                     /translation="MKLTIHEVAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGVRDGHDFIERAFENGAAATLSEKEVANHPYILVDDVLTAFQQLAAYYLEKTAVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIRLAFQHLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGVQSVQLHNQMILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            61528..62139
                     /locus_tag="VQT46_000058"
     CDS             61528..62139
                     /locus_tag="VQT46_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2370172.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDLLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIADLQFFAIDPLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            62230..62934
                     /locus_tag="VQT46_000059"
     CDS             62230..62934
                     /locus_tag="VQT46_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET2370173.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            63153..64526
                     /gene="ftsA"
                     /locus_tag="VQT46_000060"
     CDS             63153..64526
                     /gene="ftsA"
                     /locus_tag="VQT46_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET2370174.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENIIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            64543..65802
                     /gene="ftsZ"
                     /locus_tag="VQT46_000061"
     CDS             64543..65802
                     /gene="ftsZ"
                     /locus_tag="VQT46_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET2370175.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            65807..66478
                     /locus_tag="VQT46_000062"
     CDS             65807..66478
                     /locus_tag="VQT46_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET2370176.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            66488..67027
                     /locus_tag="VQT46_000063"
     CDS             66488..67027
                     /locus_tag="VQT46_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET2370177.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            67027..67290
                     /locus_tag="VQT46_000064"
     CDS             67027..67290
                     /locus_tag="VQT46_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET2370178.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            67287..67971
                     /locus_tag="VQT46_000065"
                     /pseudo
     CDS             67287..67971
                     /locus_tag="VQT46_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
     gene            67980..68768
                     /gene="divIVA"
                     /locus_tag="VQT46_000066"
     CDS             67980..68768
                     /gene="divIVA"
                     /locus_tag="VQT46_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET2370179.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            69116..71908
                     /locus_tag="VQT46_000067"
     CDS             69116..71908
                     /locus_tag="VQT46_000067"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET2370180.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYANFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEEPAPEAALSFEDVVFTVERAAGEVCDRCRRIDPTTAERSYHAVICDHCASI
                     VEENFADAVAEGFEEK"
     gene            72318..72680
                     /locus_tag="VQT46_000068"
     CDS             72318..72680
                     /locus_tag="VQT46_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370181.1"
                     /translation="MKSSGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGATAGAFS
                     GVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGWVGGILA
                     IIGGSLFLATLKKFKSEE"
     gene            73215..73907
                     /locus_tag="VQT46_000069"
     CDS             73215..73907
                     /locus_tag="VQT46_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET2370182.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIEFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            73960..76371
                     /locus_tag="VQT46_000070"
     CDS             73960..76371
                     /locus_tag="VQT46_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2370183.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLIQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLETVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYSGNLFSY
                     KGQEYIEAARAILNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            76621..77322
                     /locus_tag="VQT46_000071"
     CDS             76621..77322
                     /locus_tag="VQT46_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370184.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            77324..80024
                     /locus_tag="VQT46_000072"
                     /pseudo
     CDS             77324..80024
                     /locus_tag="VQT46_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            complement(80120..80611)
                     /gene="tpx"
                     /locus_tag="VQT46_000073"
     CDS             complement(80120..80611)
                     /gene="tpx"
                     /locus_tag="VQT46_000073"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET2370185.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(80734..81663)
                     /gene="psaA"
                     /locus_tag="VQT46_000074"
     CDS             complement(80734..81663)
                     /gene="psaA"
                     /locus_tag="VQT46_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET2370186.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(81695..82543)
                     /locus_tag="VQT46_000075"
     CDS             complement(81695..82543)
                     /locus_tag="VQT46_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2370187.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(82540..83262)
                     /locus_tag="VQT46_000076"
     CDS             complement(82540..83262)
                     /locus_tag="VQT46_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2370188.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
BASE COUNT        25209 a        15195 c        18403 g        24549 t
ORIGIN      
        1 ctaacagttg aagataaagc ctataaccat gcgctatcta aggagagaag caaggttgag
       61 aacatctttg ccaaagtaaa aacgtttaaa atgttttcaa caacctatcg aaatcatcgt
      121 aaacgcttcg gattacgaat gaatttgatt gctggcatta tcaatcatga actaggattc
      181 tagttttgca ggaagtctac tactttcctt attgtctgta aatctactga ccttgttgtt
      241 tatcccagtc atggtttcta gttcgggctc agagtttcaa agtggatggc aagagcatca
      301 attgattgct gagaaggtta gtaaaacact tgataagaca tttgataagg atgtcagaga
      361 aattccgacc agtcagtttt atcaaaaatt tgtagatgag atgggaagga tttactcagg
      421 aaatttgatc ctccaggagc tgataactgt gaatggagct tataaagcta cttatatcgg
      481 tgaactctct agcaactaat cattctttaa aatgatgacc aataagaggc ttgatttggt
      541 gaatcaagtc ttttttctct cttttactgc catttgtgat aaaatagtat agaacgattt
      601 tttacatgaa tgataaaaca gaggtaaata tgacaatcgg tattgataag attggttttg
      661 cgaccagtca atatgtcttg aaattacaag acttagcaga agcgagggga attgaccctg
      721 aaaaattaag taaaggactc ttactcaagg aattgagtat tgcgccccta actgaggaca
      781 tcgtgacctt ggcggccagt gctagtgact ctattttaac tgagcaagaa agacaagaag
      841 ttgacatggt cattgtggct accgagtcag gaattgacca gagtaaggct gcggccgtct
      901 ttgtgcatgg cttgctgggc atccagccct ttgctcgtag tttcgagatt aaagaagcct
      961 gctatggggc gacagctgcc ctccattatg ccaaattgca tgtggaaaat tctccggagt
     1021 ccaaggtctt ggtcattgcc agtgatattg ccaaatatgg tattgaaact ccgggagaac
     1081 caactcaagg tgctggaagt gtagctatgt tgattacaca aaatccacgc atgatggcct
     1141 ttaataatga caatgtagct cagacccgtg acatcatgga tttctggcga ccaaattact
     1201 cgacaactcc ttatgtaaat ggtgtctatt ctacccaaca atacttggat agtttgaaaa
     1261 cgacttggct tgaatatcaa aaacgctacc agcttactct ggatgatttt gcggctgttt
     1321 gtttccactt gccttatcct aaattagcgc taaaaggctt gaaaaaaatc atggataaga
     1381 gcctgcctca agagaaaaaa gacctcttac aaaagcattt tgaccagtct attctctaca
     1441 gtcaaaaggt ggggaatatc tacacaggtt cacttttcct tggacttttg tctctcttgg
     1501 aaaatgcaga tagcttgaaa gctggggata aaatcgccct ttatagttac ggaagtggag
     1561 ctgtggctga gttcttcagt ggtgaattgg ttgaaggata tgaagcttat ttggataaag
     1621 accgcttgaa caagctcaac caacgaactg ccttatccgt tgcagactat gaaaaggtct
     1681 tttttgagga agtaaacttg gatgaaacaa actctgccca gtttgctggc tatgaaaatc
     1741 aagattttgc cttggttgaa attctcgacc accaacgccg ttatagcaag gttgaaaaat
     1801 aatgaagata agttggaatg gattttctaa aaaatcatac caagagcgcc tcgagctgtt
     1861 aaaagctcag gcgctcctta gtcctgagag acaagctagt ctggagaagg atgaacagat
     1921 gagtgtgact gtggcagacc agctgagtga gaatgtagtg ggaacttttt ctctgcctta
     1981 ttcgctggtt ccggaggtac ttgtcaacgg tcaggaatac accgttccct atgtgacaga
     2041 agaaccctct gtggttgcgg cggccagcta tgccagcaaa atcatcaagc gtgcaggtgg
     2101 ttttactgca caagtccatc agcgccagat gattgggcag gtagcccttt atcaagttgc
     2161 taatcctaaa ctagcgcaag agaagattgc cagcaagaaa gcggagctct tggagtttgc
     2221 caatcaagcc tatccttcta tcgttaaacg tggaggtggg gcgcgtgatc tgcatgtcga
     2281 gcagataaaa ggcgaaccag actttctcgt tgtttatatt catgtcgata cccaggaagc
     2341 catgggtgcc aatatgctca acaccatgct ggaagccttg aaaccagtct tagaagaact
     2401 cagtcaggga cagagtctca taggaatcct gtccaactac gcgaccgatt ctctggtgac
     2461 tgcaagctgt cgcatggcct ttcgctactt gagccgccaa aaggatcaag gacgagagat
     2521 tgcggagaaa attgcgttgg ctagtcagtt tgcgcaggct gatccttacc gagctgctac
     2581 tcataataaa ggaattttta atggtattga tgcgattttg attgccactg gtaatgactg
     2641 gcgtgccatc gaagctgggg cccatgcctt tgccagtcga gatggacgct atcaaggtct
     2701 tagttgctgg acgctggacc ttgaaagaga agaattggtc ggtgagatga ccctgcccat
     2761 gcctgtagcg actaagggtg gctctatcgg cctcaaccca cgtgtagctt tcagtcatga
     2821 tctactagga aatccttctg ccagagaatt agcccagatt atcgtgtcca tcggtcttgc
     2881 ccaaaatttt gcagccctca aagctttggt aagtacgggc atccagcaag gccacatgaa
     2941 actacaggcc aaatccctag ctctcctagc tggggctagt gaatctgaag ttgctcccct
     3001 agtagagcgc ctcatctcag ataaaacctt taacctagag acagcccagc gctatctcga
     3061 aaatttaaga tcataaaaaa ctcagacgaa tcggtctgag ttttcttgtg tttaaatact
     3121 ttttcctggt aatagtgtaa ctggtaagaa gtaaccagtt gtggcaactt ccttgccttc
     3181 aatcttttgc aagagaagat caatagtgag acaagcaatc tcttccaaag gttgcttgat
     3241 agtagccaat tgagggtagt aattttcgat aaagtaggtc ccatcatagc cgatgacctt
     3301 gagctctttt gggacagaaa tgcccaattc ttgagcgatt ttaatgacca gaatagctgt
     3361 caaatcatcc gaagcaaaaa tggcatctgg tttttcccgg gtcaagatat tcttgatttc
     3421 catttctttt ctgacgggag aaaagtcact ggaaacattg ataataggag cttttgggag
     3481 tacggatgca aaaccagcgt ggcgtagtcc ggttggcgaa ttggaattgt cattccctgt
     3541 aatcatgatg atagtctggg cacctgtctt gaccaaggtt tgggcagcaa gaaccccacc
     3601 agcatagttg tcagaggaga cgacagggat gtctggcgat aggtttcggt caaaggaaat
     3661 aatcggcgct gtcacacgat tgtagtcttc gattcctagg ttgtgactac cagaaatgat
     3721 gccgtccacc tgattggctt ccaacatttc gatgtattcg cgttccttct cagaatcatg
     3781 ttcactgttg cagatgatgg tcttgtaacc atttttgaag agttggtgtt ccaatttatc
     3841 aatcaattct gcatagaaaa cattggaaat attagggaaa atcaagccga ttaacttagc
     3901 tgattttcct tgcagactac gagccaggtt gttgggttta tagcccaatt ctcgcatggc
     3961 ttcattgact ttttggatgg ttttctcaga tagataccct tttttattga taacccgaga
     4021 aacggtagta ggactgacgc ctgcaagttt ggcgacatca gttagttttg cgaccataat
     4081 ctaattcata gtaagttcca gttgggtttc cagatttgat caggatacca ttttggtccg
     4141 catgtgggaa gacacgacca gaaaatactt tttctccttt attgatgaaa atttcaaaga
     4201 cagagttatc gatgaagatt gtagcagtag tagcctgatt ctcgataggg caagaacgag
     4261 ttgtcccaaa ttcttgggca tactgttctc cagcctggct acgatccact gtcacttgac
     4321 cgtttacaag gtcaaagttg attgaaagtc ccttaccttc tttatcagca agtaagacaa
     4381 tctcgctctg gctattagct tccaagttga gttcaagttc gtaagtgttc ttggtttggg
     4441 aacggtttga gaaggcttct tcagaagcac gaaggtcctt aatagcagcg actggatact
     4501 ggtagagctt gtcgtctttg atagtgagtt ccttgaccaa agagaaggtt ccttggtggt
     4561 caaaacggtc agatgggtaa gaaacatctg gcaaaccaag ccagctaact gctagagcac
     4621 gcccatcagg agcgttgaag gcttgagttg cataggcttc gaaaccgtaa tccatgtttt
     4681 gaagttgaga cacatctacc attttggcat ttttagggtc aaaggaagcc ccaatcttat
     4741 acatatttgg aaagatatta tcgtagtcta gaactttctt atccaatcct tgtggacagt
     4801 agagaaggac aggatgttcc tctacaaaga ccagattagg acattccatc atgtaggcag
     4861 tacggtcgtt agcaaagtca aggtcgccaa ctgcttgcca gtttgtgtag tcgttattga
     4921 cagccttgta gagacggacg aagccttttt tctccaagtc ctgtccaccg acgacagcat
     4981 agtattgact tttaaagtta aaaatttgtg gatcgcggaa gtggtcagta gagtctgctg
     5041 gctggtcaat caagatcttg tcaatctttg taatcttacc ctccttgtcc atcaaagcac
     5101 cgatctggta tgggtgacgg atccagtttt catcgcgaac atttcctgta taaaatagga
     5161 ataagttatc gccaaattgc atggcagaac cagagtaggc accgtggcta tctaatggag
     5221 tatctggtaa aactttgatt ccagtttctt taaagtgaac caaatcatca ctttctagct
     5281 gtgcccaaga tttcaaaccg tgggctgcac caaaaggaaa attctggtaa aagaggatcc
     5341 acttgccatc aaagtaagaa aagccatttg ggtcgttgag aagtcctgtt tttggctcaa
     5401 catggtaatg agtatgccat ggagattgtg ccatattttc ctttatatgt tgaatttctt
     5461 cttgcgtcca atcttgataa agtctgtaac gacgctcagt tgtccattcc attcattcct
     5521 ccaaaaatct tatcactttt aatagtaact gttttcgata aaaaatgcaa gccttttatg
     5581 ttaaaaaaga ggaaaaactg tcaaacgatt atcataaaat aaatacagga aatcaatcaa
     5641 atttttacga aaatgtgaaa gataatgaaa taaaagactt tttaaccaag gtttcaaact
     5701 tatttttcaa ggaattcctg atgaaacagt caaaaacaat caatctaaaa cttgcccact
     5761 aagtggatag aatatttttt ctgcaaaacg cttgacatat ttttaaaaca tgataaaata
     5821 atagtcgtaa gggcgaataa aatcgctttc aaacaagaac aaaatgttat ataaggagat
     5881 ttttgcaaat gaacaatcag gaaattgcaa aaaaagtcat cgatgccttg ggcggacgtg
     5941 aaaatgtcaa tagtgttgcc cactgtgcga ctcgtctacg tgtcatggtc aaagatgaag
     6001 agaaaatcaa taaagaagtg attgagaact tggaaaaagt tcaaggtgct ttctttaact
     6061 cagggcaata ccaaattatc tttggtacag gtacagttaa caaaatgtac gatgaagttg
     6121 ttgtacttgg cttaccaaca tcatctaagg atgacatgaa agcagaagtt gctaaacaag
     6181 ggaactggtt ccaacgtgct atccgtactt tcggtgatgt tttcgttcca atcatcccag
     6241 ttatcgtagc gacaggtctc ttcatgggtg tgcgtggtct tttcaacgct cttgaaatgc
     6301 cacttccagg tgactttgca acttacacac aaatcttgac agatacagcc ttcatcatct
     6361 tgccaggttt ggttgtgtgg tcaaccttcc gtgtatttgg tggaaatcct gccgttggta
     6421 tcgttcttgg tatgatgctt gtctctggct cacttccaaa cgcttgggca gttgctcaag
     6481 gtggtgaagt aacagcgatg aacttctttg gtttcatccc tgttgttggt ttgcaaggtt
     6541 ccgttcttcc agccttcatc atcggggttg tcggagctaa atttgaaaaa gctgtccgca
     6601 aggttgttcc agatgtcatt gacctcttgg taacaccatt cgtgacactt ttggtcatgt
     6661 ctatccttgg actctttgtc attggaccag ttttccacgt tgttgaaaac tacatcctta
     6721 ttgctacaaa agcgattctt agcatgccat ttggtcttgg tggtttcttg attggtgggg
     6781 ttcaccaatt gatcgtcgtg tcaggtgtgc accacatctt caacttgctt gaagtgcaat
     6841 tacttgctgc tgaccatgct aacccattca acgctatcat cacagctgct atgacagctc
     6901 aaggtgctgc tactgttgcg gttggtgtta aaacaaaaaa tccaaaactg aaaacacttg
     6961 ctttcccggc tgctctttct gccttcctag gtattacaga gcctgctatc ttcggggtga
     7021 acttgcgctt ccgtaaacca ttcttccttt cattgattgc tggtgcaatc ggtggtggat
     7081 tggcttctat ccttggactt gctggtactg gtaatggtat caccatcatc cctggtacaa
     7141 tgctttatgt tggtaacgga caacttccac aataccttct tatggtagct gtatcatttg
     7201 cccttggttt tgctcttact tacatgtttg gttacgaaga tgaagtagac gcaactgcag
     7261 ctgcaaaaca agctgaagtg gctgaagaaa aagaagaagt tgcgccagca gctcttcaaa
     7321 atgaaacact tgtaactcct atcgtcggtg atgttgtcgc tcttgctgat gtcaatgacc
     7381 cagtcttctc aagtggagct atgggacaag gtatcgctgt gaaaccaagt caaggcgtgg
     7441 tctatgcact agctgatgct gaagtttcaa ttgcctttcc aacagggcac gcttttggtt
     7501 tgaaaacaag aaatggtgct gaagttttga ttcacgttgg tattgacact gtatctatga
     7561 acggtgacgg ttttgaagca aaagttgctc aaggtaataa ggtgaaagct ggcgatgttc
     7621 ttggaacatt tgactcaaac aaaatcgctg cagctggact tgatgataca acaatggtta
     7681 tcgttacaaa tacagctgac tacgcttcag tagctccagt cgcaacaggt tcagtttcga
     7741 agggggatgc tgtgatcgaa gtgaaaatct aatcaatcct ctctaatgtg aaaacgaaca
     7801 aatgacatgt ttgttcgttt ttattagata gtaagattta cagaggaaaa tctaaaaaat
     7861 agagacattt agactttcga agtatgctat aataaagaaa ataaaaacaa gaggtttatc
     7921 atgacaaaat tatatggaag cttggaagcg ggcggtacaa agtttgtctg tgctgtcggt
     7981 gatgaaaact ttaacgttgt agaaaaaaca caatttccaa caacaactcc aatcgaaaca
     8041 atcgataaaa ccattgagtt cttctcaaaa ttcgataacc ttgctggtct tgcagttggt
     8101 tcatttgggc cgattgatat tgacaaaaac tcaaaaactt atggctttat cacgacgact
     8161 ccaaaaccaa actgggcaaa tgtggacttg cttggtgccc ttcgtcgcgc cctaaacgtg
     8221 ccaatgtact tcacaacaga cgtaaacagc tctgcttacg gtgaaatggt tgctcgtaac
     8281 aatgctggtg gtcgtatcga aaacttggtt tactacacaa tcggtacagg tatcggtgca
     8341 ggcgtcatcc aacgtggtga gtttatcggt ggtgtgggtc accctgaaat gggtcattat
     8401 tatgttgcta gacacccaat ggatattgaa aaagagttta agggtgtttg tcctttccat
     8461 aagggatgtc tagaaggtta tgcagctggt acaagtttgg aagctcgtac aggtgtacgt
     8521 ggggaaacta ttgaactcaa caaccctgtt tgggatgttc aagcctacta tatcgctcaa
     8581 gctgcggtta atgcgacagt gactttccgc ccagacgtga ttgtctttgg tggaggggtc
     8641 atggctcaac aacatatgct ggaccgtgtc cgtgagaaat ttacatctct tcttaatggt
     8701 tacctaccag taccagatgt gcgtgactat atcgtgacgc cagcagtcgc aggaaatggt
     8761 tctgccacac ttgggaactt tgttcttgca aaagaagttt caaaataaag cacaaaatcc
     8821 gcttgggaaa ccaaacggat tttgtggttg aaaacaatat ttttgagcct ttccttaagt
     8881 gattacggac ggtagcgact ttcttcgaaa ttccatacct aaactttgag cctagtgtct
     8941 caaagtttcc gaatacctga aaccattaga tttcaggtgt ttctatcacg gcggaaaggc
     9001 taggtaagtc ctcgcctcac tatcgaaaaa tatgcataat ttccatacca aagtatattt
     9061 agtatcaagc tatagttaat ctacgcttta aaaatccact tgggaaacca aacggatttt
     9121 ttacgtgtca aagcatttgc cagaaaaagt caataatata ggtcagaccg taggtataaa
     9181 ccacgagggt aaagggtttg gtcagaatga tgatagtcat gtagcgcttg aaactcatct
     9241 tggtcagggc ggccagcata cagagaaagt cagctgggct aatgggccaa atcatcataa
     9301 aaataaagaa gcggtcaaaa cgattgccct tatctagcca gccgatgtac ttgtcgtagg
     9361 tgcgcttgct gacgacagac tggacaaagg cagctccgta taggcgcact agataaaaga
     9421 taatggcaca gccaatcacg atgccgatat agttgtagat agtcccgatg atgtgcccgt
     9481 agataaagac cccagccacc gaggtcaagg cccctggaat gatagggacg acagtctgta
     9541 aaatctgtaa aaagataaag agaggtggac cccagatgcc tgcctgctgg ataaaggcag
     9601 agagggtttc cttggattgt aaaatcccag cctgataagc ccaaatacag aaaatcaaac
     9661 tcccaacccc accgacaatc gatgagatat tgataactcg ctgcagaagg ggagaaacag
     9721 ctttcatttg tttatcctgt gacatgtaaa ctcctcatag atagtatatt tctactatac
     9781 catattttgg aggagaaagg gggaatgagt cttttttgat aaggaataga aagtaaatag
     9841 cccttcgaga cttagaatag gtctgtcaac taaaggttat atgcattcta ggtttcgaat
     9901 aatcgcaatt ccataaattt aaaagtattc taagtttcga atagcttatc tgagataatt
     9961 ttgaggcatt cgcgctttcg aatagtcatt ttccctaaag tttatatgta ttctgaagct
    10021 agaaagacta aaatataaaa gtagtaagag tctctctctg atggacgtaa tttatggcta
    10081 gtatgaatcc tttgaattgt tagttaattt taatattaat cagttctgaa ataattacta
    10141 aatatagtta gatggtgagt taattattgc taaatttcaa gttcaagtta gtcatccaga
    10201 agtcttctct gggggacttg tagttcaagc attttttagg atagttgtta atccactttt
    10261 cgataaatgc gacttccttt gtagttgttt tcttagttcc ctgaggtaac catctatgaa
    10321 tgagcctgtt gtgattttca ttagatccta tagtgatgtg cataatagat atagcagatt
    10381 gaaactagaa tagtatacat ctacttctaa aacattgtta gaaatcaatt tgactgtcct
    10441 gatcaatttg tcctgttttt atttcatttt actatataat ccttagaaaa catatcggac
    10501 aagcggttga attccgttcc gtccattagt agataaagga ttactccttc ttgaaatgac
    10561 agatgaactt gtttcttata aaaatgttgt ctgaaactat tagccttttt ccagaagttt
    10621 tagaggaaga aaactttacg aggaaaaagg agttactcaa ataacaattc aggattaaaa
    10681 atagacagtt gaggagcgga aggtataaat taagtttgct actgtataat ggatttatca
    10741 ctaatactct tcgaaaatct cttcaaacca cgtcagcttc gccttgccgt agatatagtt
    10801 actgacttcg tcagttctat ccacaacctc aaaacagtgt tttgagctga cttcgtcagt
    10861 tttatctgca acctcaaagc tgtactttga gcagcctacg gctagcttcc tagtttgctc
    10921 tttgcttttc attgagtata aaagtgctcc aggccatatt ttacacagca atagtcttct
    10981 aaaaatggac aaaaacattg taaaggctat caaaaaggag tataatgagt gcaagaaatt
    11041 tcggaggtga aagatgctag aagtaagaag tctagagaaa agttttggct ccaagcaagt
    11101 tttgtttggt attgactttc aagcgcgacc aggtcgtatt ttgggactag tcggaaaaaa
    11161 tggtgctgga aaaacaacga ttttccatag tattttgaaa ttcctagaat atcagggaga
    11221 aatcggtctg gatggtcagg atattcgtca ggagacctat gctcggattg gttatctgcc
    11281 tgaagaacgc agtctcatgc ctaaattgac agttcttgaa caagttcgct acttggcgac
    11341 tctaaaaggc atggatgcca aagaagtcaa agaaaaactc cctcaatgga tgaagaggtt
    11401 ggaagtgaaa ggaaagctga cagataaaat caagagtctg tcaaaaggaa atcagcagaa
    11461 gattcagctc attattactc tgattcatga accagacctg attatcttgg atgagccttt
    11521 tagtggattg gacccagtta atacagaatt gctcaaacaa gtcatttttc aggaaaaaga
    11581 gcgcggagca accattatct tttctgacca tgtcatgacc aatgttgagg aactttgtga
    11641 cgatattctg atgatccgag atggccgtgt ggtcttgcac ggaccagttc aggatgtccg
    11701 caatcaatac gggaaaacgc gtctctttgt ttcaagtgaa cgaagcaagg aagaattgga
    11761 aaatcttcct catgtcaaac aggtgagctt gaccaaacaa ggcagttgga aattgatttt
    11821 ggaggatgag agcgctggaa gggaactctt cccaatcttg actcaaggtc aatatatcgc
    11881 aacatttgac caacaagcgc caactatcga tgaaatcttt aaactagaat caggagtgga
    11941 agtatgagaa atatgtgggt tgtaatcaag gaaacctatc ttcgacatgt cgagtcatgg
    12001 agtttcttct ttatggtgat ttcgccgttc ctctttttag gaatctctgt aggaattggg
    12061 catctccaag gttcttctat ggctaaaaat aataaagtgg cagtagtgac aacagtgcca
    12121 tctgtagcag aaggactgaa gaatgtaaat ggtgttaact tcgactataa agacgaagca
    12181 agtgccaaag aagcaattaa agaagaaaaa ttaaaaggtt atttgaccat tgatcaagaa
    12241 gatagtgttc taaaggcagt ttatcatggc gaaacatcgc ttgaaaatgg aattaaattt
    12301 gaggttacag gtacactcaa tgaactgcaa aatcagctta atcgttcaac tgcttccttg
    12361 tctcaagagc aggaaaaacg cttagagcag acaattcaat tcacagaaaa gattgatgaa
    12421 gccaaggaaa ataaaaagtt tattcaaaca attgcagcag gtgccttagg attctttctt
    12481 tatatgattc tgattaccta tgcgggtgta acagctcagg aagttgccag tgaaaaaggc
    12541 accaaaatta tggaagtcgt tttttctagc ataagggcaa gtcactattt ctatgcgcgg
    12601 atgatggctc tgtttctagt gattttaacg catattggga tctatgttgt aggtggtctg
    12661 gctgccgttt tgctctttaa agatttgcca ttcttggctc agtctggtat tttggatcac
    12721 ttgggagatg ctatctcact gaataccttg ctctttattt tgatcagtct tttcatgtac
    12781 gtagtcttgg cagcattcct aggatctatg gtttctcgtc ctgaggactc agggaaagcc
    12841 ttgtcgcctt tgatgatttt gattatgggt ggtttttttg gagtgacagc tctaggtgca
    12901 gctggtgaca atctcctctt gaagattggt tcttatattc cctttatttc gaccttcttt
    12961 atgccgtttc gaacgattaa tggctatgcg gggggagcag aagcatggat ttcacttgct
    13021 attacagtga tttttgcggt ggtagcaaca ggatttatcg gacgcatgta tgctagtctc
    13081 gttcttcaaa cggatgattt agggatttgg aaaaccttta aacgtgcctt atcttataaa
    13141 tagaagagcc ttgcgaaagc gaggttttta aaggtgaaaa gggtggaatc acgaacctaa
    13201 tgatgtacac attatgtaaa caggttgctt gaaaactcaa ttgtatagtg aactgaatct
    13261 ggaataggat aatattactt ctaaaacatt cttataaatt gatttgaatt ccaaaatccc
    13321 atcgttccgt tcttatttca ttttgcgata tagtgaaagg aaataagtca gctcacaaaa
    13381 aacgcataat atcaaggatt tttaacactt gatactatgc gttttctaat tttaaagact
    13441 ttttgcctgg tctcttttgt tctatgagta tgttacatat ctaggtaaaa attatttaaa
    13501 gcaaattaac cttatttctc aagatgtagt aggttccgag ataaaagata gctatgaata
    13561 tgagttcttt aacaatggct atacctgctc ccatatagaa atggtcattg agtcctacca
    13621 gtgaattgac atagaaatta gaactaagat tgaagaaaag ttcaataaat ccaatgacga
    13681 tttggatacc aatgtaggct gcaacagcga gtgctgtacg gtattcattg aaaagctgtc
    13741 caatggaaat agccaggtag atgcagagga ttcctgaaat ggtatttagt aggaaggata
    13801 tacctgtaag aaagatctga gggagatgtg tttctacaaa tgtaatcaca taagaaagag
    13861 gaatccattc tggagctgtt aaagccagaa taataacagc acttagagcc aatacagcgg
    13921 tgctaatcaa tgaccagata aaggcaccga ttagtttggc tgtgatgata tggtgttcag
    13981 aaactggcaa ggtcaaagtc agatagcctt gtcggtcgta gacactacct ttgaagcgtt
    14041 taataatcaa gaaaatggtt gaaatcgcaa gtgtaagcat caagccacca aagactgtag
    14101 ctagaaaaag tagcatagta gcctgacttt cttggtaagg tagattttta aagccttgtg
    14161 tctgtattcc gatgagggca gaaaggacta gcacggctgc gtagagggct aaataccact
    14221 tgttaacatt tttaaattcg tagtgaacta aattccaaaa cataaataat ctcctttgct
    14281 taggccttaa attcctgacg gaagagttgg tcaatggatt cacctgactc gtagcgaata
    14341 tcatctacat ttccttgacg gacgactttt ccgtctttta ggaagacaat ttcatccaag
    14401 attggctcga tatcagaaat caagtgggta gaaatcaaaa cggtagaagt tggtgagtag
    14461 ttgttgataa tggtattgag gatataagca cgggctgctg gatccacccc accaatgggt
    14521 tcatccaaaa catagagacg agcatcacgg ctcataacca aaatcagttg aaccttttct
    14581 ttgtttcctt ttgatagttt cttgagacga ctattttcat caatgcccag gtctgcaagt
    14641 agatgatgag cgcgttcaag attgaaatct ttatagaagg tcttgaagta ggttagggct
    14701 tctttgacct tcatttgctc attgagatag gtcgtatcag gcaaataagc tacaacggcc
    14761 ttggttgctg ggcttgggtc catgtcgttg atgaggacac gtccttgatc tggttgtaag
    14821 aggccattaa ttagtttaat cagggttgtt tttcctgagc cgtttggccc aagaaggccg
    14881 acaatttttc cagctggaat gtcaagagaa acattttcaa gggctggtgt tgctccatat
    14941 gatttggata cattttcaaa tactagtaat gacataggct taaactcctt taatataatc
    15001 actgactacg cctggtagtt cttctttttc atagccaaaa tggatcatgg aggaaacgaa
    15061 gtgttccaat tcttcttctg ataattgttt gcgtgactga gcgattagct ccttatcctt
    15121 agtcacaaat cgtccagttg ttcgcttgct gtagacaaat ccttctcgtt caaggtctga
    15181 taaggctctt tggatggtat tgggattgac accagcctcg ctagctagct ccctcacggt
    15241 tggaagttgt tgattgggtt ccagtgtatg ggaaacaatc tgaagcttga ttttctccat
    15301 aatctgtaaa tagatgggtt ttttgttgtc aaatgtccag gacatcttag tctcctttct
    15361 cttatccttt tgtcttaact aaataataca acaaaacaaa aaacttgtca agcaaaaaga
    15421 agaattgttt tgggaatcgc ttaaaaaatg gtataatgaa aagaaaacga taaggaggga
    15481 aaggatgcgt tgtccaaaat gtggggctac caagtcaagt gttatcgata gtcgccaagc
    15541 agaagaaggg aacaccattc gtagaagacg tgagtgcgac gaatgccaac accgttttac
    15601 aacctacgaa cgagtagaag aaagaacctt agtggttgtt aaaaaagatg gtacacggga
    15661 acaattctcc agagataaaa tctttaatgg gattatccgc tcagcccaga aacgtcctgt
    15721 gtcaagtgat gaaatcaaca tggtagtcaa tcgtatcgaa cagaaactcc gtggtcgaaa
    15781 tgaaaatgaa attcaaagtg aggacattgg ttcactcgtc atggaggagt tggctgaatt
    15841 ggacgagatt acctatgtac gttttgctag tgtctatcgt agttttaagg atgtcagtga
    15901 gttagagagc ttgctccaac aaatcaccca gtcctctaaa aagaaaaagg aaagataaat
    15961 gaagccaatt gaccgttttt cttatctaaa gaataatcgg gtgtcgcaag atacctcatc
    16021 tctggtacag tgctacctcc cgattatcgg tcaggaggca ctgagccttt atctttatac
    16081 aatcagtttt tgggataatg gtagaaagga atatcttttt tcaagtatcc tcaatcatct
    16141 caactttggg atggatagac tgataaaatc attgaaaatc ttatctgctt ttaatctctt
    16201 gaccctctat caaaaggggg atgtttatca gctagccctc catgctcctc tatctagtca
    16261 agacttcttg gagcatcctg tttatcgcag actcttagag aaaaagattg gcgactctgc
    16321 tgtggaggat ttgaaagttg aaagtgctga tggtgaagaa atacctgtct cactcaatca
    16381 agtctttcca gaattggcag aactaggcag tcaagaagac cttggtctca agaagaaagt
    16441 ggccaatgat tttgacttgg aacattttcg ccagctgatg gctcgagatg gacttcgttt
    16501 tgcggatgag cagtccgatg tcttaaacct ctttgctatt gccgaggaga agaaatggac
    16561 ttggtttgaa acctatcaat tggccaagtc aacagctgtt tctcaggtta tttcaaccaa
    16621 acgcatgcgt gaaaaaattg ctcaaaaacc agtttcctct gactttaatc ctaaggaagc
    16681 aaccattatc aaggaagcta aaagtaagac tgccctgcag ttcttagcag aaatcaagca
    16741 aacacgcaag gggaccatta cccaaacaga aagagaactt ttgcaacaga tggctggctt
    16801 gggcttgctg gacgaagtca tcaatatcat tctcttgttg acctttaata aggtggattc
    16861 ggcaaacatc aatgagaaat atgccatgaa ggtggctaat gactatgcct atcaaaagat
    16921 acattcagca gaagaggccg ttttacgaat tcgtgagcga gggcagaaaa caaaaacaca
    16981 aaaacagaat cagactgccc cagcaaaaac caatattcct aaatggagta acccagatta
    17041 taagaatgaa accagcgagg aaactcgtct ggaactagaa cgtaagaaac aagaactatt
    17101 agctcgatta gaaaaaggag gagattagat ggaaagtgtc ggagacgtac tcaaacgtca
    17161 acccagccgt ttttattatc aagatttggt ccagaaaatc atgaaggacc ctgatgttgc
    17221 ggcttttatc cagcaagaat ccttgactcc agaggaatta aatcgcagta tctccaagtt
    17281 taatcagtac atcaccgagc gtgacaagtt tctccgtggg gatacggatt atattgccaa
    17341 aggctacaag ccgattttgg ttaagaatca tggctatgca gatgtttcat atgaagaaac
    17401 tcctgagcta atcgcggctg aaaaagaagc ggctattaag aatcgtctca agctaatcaa
    17461 tctaccagcc agtctcaaaa aagctagttt ggctcaagtt gatttggatg atttgggacg
    17521 cttgccagtt tttgaaaaac tattagcctt tgtggagcaa tatccagcta ttcgaaaagg
    17581 tctttactta tatggagact ttggtgtggg taaaagtttc atggtggcgg ccttagctca
    17641 tgatttatca gaaaaacgtg gtgtttcatc aactctcctc cactatccta gctttgtcat
    17701 tgatgtcaaa aatgctatca gtgatggcaa tgttaagacc ttggtggatg agattaagct
    17761 gtctgaggtc ctgattttag atgatattgg cgccgagcaa tcaaccgctt gggtgcgtga
    17821 cgaaatcctg caggtcattc tccaatatcg gatgcaggaa aatttaccga cctttttcac
    17881 atccaacttc aactttgaag atttggagaa gcattttgcg aaagtgaaac atggaaatga
    17941 cgaaacctgg gaagccagac gggtcatgga acgcatccgt tatttggctg aggagactcg
    18001 tttagaagga gtaaaccgtc gatgacagaa accattaaat tgatgaaggc tcatacttca
    18061 gtgcgcaggt ttaaagagca agaaattccc caagtagact taaatgagat tttgacagca
    18121 gcccagatgg catcatcttg gaagaatttc caatcctact ctgtgattgt ggtacgaagt
    18181 caagagaaga aagatgcctt gtatgaattg gtacctcaag aagccattcg ccagtctgct
    18241 gttttccttc tctttgtcgg agatttgaac cgagcagaaa agggagcccg acttcatacc
    18301 gacaccttcc aaccccaagg tgtggaaggt ctcttgatta gttcggtcga tgcagctctt
    18361 gctggacaaa acgccttgtt ggcagctgaa agcttgggct atggtggtgt gattatcggt
    18421 ttggttcgat acaagtctga agaagtggca gagctcttta acctacctga ctacacctat
    18481 tctgtctttg ggatggcact gggtgtgcca aatcaacatc atgatatgaa accgagactg
    18541 ccactagaga atgttgtctt tgaggaagaa taccaagaac agtcaactga ggcaatccaa
    18601 gcttatgacc gtgttcaggc tgactatgct ggggcgcgtg cgaccacaag ctggagtcag
    18661 cgcctagcag aacagtttgg tcaagctgaa ccaagctcaa ctagaaaaaa tcttgaacag
    18721 aagaaattat tgtagaaagt gagaaattat ggccctacca actattgcca ttgtaggacg
    18781 tcccaatgtt gggaaatcaa ccctatttaa tcggatcgct ggtgagcgaa tctccattgt
    18841 agaagatgtc gaaggagtga cacgtgaccg tatttatgca acgggtgagt ggctcaatcg
    18901 ttcttttagc atgattgata caggaggaat tgatgatgtc gatgctcctt tcatggaaca
    18961 aatcaagcac caggcagaaa ttgccatgga agaagcagat gttatcgtct ttgtcgtgtc
    19021 cggtaaggaa ggaattaccg atgcagacga atacgtagcc cgtaagcttt ataagaccca
    19081 caaaccagtt atcctcgcag tcaacaaggt ggacaaccct gagatgagaa atgatatcta
    19141 tgatttctat gctctcggtt tgggtgaacc attgcctatc tcatctgtcc atggaatcgg
    19201 tacaggggat gtgctagatg cgatcgtaga aaatcttcca aatgaatatg aggaagaaaa
    19261 tccagatgtc attaagttta gcttgattgg tcgtcctaac gttggaaaat caagcttgat
    19321 caatgctatc ttgggagaag accgtgttat tgctagtcct gttgctggaa caactcgtga
    19381 tgccattgat acccacttta cagatacaga tggtcaagag tttaccatga ttgatacggc
    19441 tggtatgcgt aagtctggta aggtttatga aaatactgag aaatactctg ttatgcgtgc
    19501 catgcgtgct attgaccgtt cagatgtggt cttgatggtc atcaatgcgg aagaaggcat
    19561 tcgtgagtac gacaagcgta tcgcaggatt tgcccatgaa gctggtaaag ggatgattat
    19621 cgtggtcaac aagtgggata cgcttgaaaa agataaccac actatgaaaa actgggaaga
    19681 agatatccgt gagcagttcc aatacctgcc ttacgcaccg attatctttg tatcagcttt
    19741 aaccaagcaa cgtctccaca aacttcctga gatgattaag caaatcagcg aaagtcaaaa
    19801 tacacgtatt ccatcagctg tcttgaacga tgtcatcatg gatgccattg ccatcaaccc
    19861 aacaccgaca gacaaaggaa aacgtctcaa gattttctat gcgacccaag tggcaaccaa
    19921 accaccaacc tttgtcatct ttgtcaatga agaagaactc atgcactttt cttacctgcg
    19981 tttcttggaa aatcaaatcc gcaaggcctt tgtttttgag ggaacaccga ttcatctcat
    20041 cgcaagaaaa cgcaaataaa aaagtagaat ctggaatgac agttccggat ttttttgata
    20101 taataaaata atagaaaacg ctatcaaaag aaggagggtg atgtcggtga tggaacattt
    20161 gtttaaattc ttacttttag caccgtactt ttattttgat aactggattg agaaggccaa
    20221 cagaaatagt aagttttttc caatttttta ttatttttac tggttttaca tccccttcta
    20281 ttctcttttt agccttgctt ggacagttgt ttcagttctg tttttcaata ccgtcttgag
    20341 aaatgtgaca gatatcaagt tatggggcat ttggtttctt tttattctgc tagctattgg
    20401 tatgaattgg ttaacttatt cctgtttcaa agaaatgttt cgcttgagac aggaactagg
    20461 gaagtctaag ggtggaaggc attgatttat atcggtttct atttgtagga ggtggcttat
    20521 ggtacctcta aaatcattta ttacacgcta ttccaaggtt tatattggta ataacattta
    20581 atagaacgaa actaaagaaa acaatttaaa agaggaggtt tgtgatggaa tacttgttta
    20641 aaatgataat cttattaccc tgtttttact ttttcagctg gattgaaaag gcaaacagag
    20701 atagtaagat tttcccaatt ttttactatt tttactggat ttacatcacc ctctatgctc
    20761 tttttagcct tgcttggaca gttttttcag ttctgttttt caatatcgtc ttgagaaatt
    20821 tgacagatat caagttatgg ggtatttggc tattattact acttatcgct tttgctagtg
    20881 actggttaga ctatatctgt ttcaaaaaaa tgcttgactt gagacgggaa ctagggaagt
    20941 ctaaaggcgg aaggcattga tttatactct tcgaaaatct cttcaaacca cgtcaacgtc
    21001 gccttggatt atatatgtaa ctgacttcgt cagtcttatc tacaacctca aagcagtgct
    21061 ttgagcaact tgcggctagt ttcctagttt gctctttgat tttcattgag tattatatta
    21121 ctttctattt gtaggaggtg gcttatgaag attcctctct taactttggc aaggcataaa
    21181 tttgtttatg tcttgcttac tttgcttttt cttgctttgg tttatcgtga tgttttgatg
    21241 acttatttct tttttgatat tcatgcgccc gatctagcta aattcgatgg acaagcaatt
    21301 aaaaatgact tattaaaatc agcattagat tttcgtattc tccagttcaa tctaggtttt
    21361 tatcaatcat ttattattcc aatcatcatt gttttgctag gttttcaata tattgagctg
    21421 aaaaataaag ttttacgatt gagtattgga agagaagtga gctatcaagg gttaaaaaga
    21481 aagttgactt tgcaagttgc aagtatccct tgtttgatat atttagtgac tgtgctgata
    21541 attgcaatta taacctattt ctttgggact ttttctcctc ttgaatggaa ttctctattt
    21601 tctgatggga gtggtttaca aagactccta gatggagaga taaaaagcta tttgttcttt
    21661 acttgtgtcc tactaatcgg tattttcatc aatgcaatct attttttaca aatagttgat
    21721 tatgtgggga atgtgactcg ttcggcaatc acctatttga tgtttctttg gcttggttct
    21781 atgctgctct atagtgcctt gccttactat atggttccta tgacgagttt gatgcaagct
    21841 agctatgggg atgtaagttt gatgaaactc tttactcctt atatccttta tgttgtccct
    21901 tatatggtac ttaaaaaata tgaagataat gtttaagaat tttaacaata tttggctaaa
    21961 gagaaagatc gttttactac ttcgtatagt tctgatgatg attttgataa actatctatt
    22021 gtcaacagcg gttcaaaagc aggatgctgt tatctttttc aagagagaat tgatttcaat
    22081 tttttcctat aatgactatt ctgaagcgaa tttagaaatc cccaaactct tgttaaacct
    22141 ttcgcttttc atggtaggat ggctctctgt cattttactt gaaagtgatt tggcagacca
    22201 ttaccatcac ttgattcgct atcaatcaag ctcctttttc gattatacaa ggaaacgatt
    22261 ggttgtcatt tctaaatttt ttactcaaga tttgtttgtc tggtttcttg gtttacttcc
    22321 gctaggaatt catttcaaaa cagtcgcact tttcttttta cttgctcagt taatgatgtt
    22381 gtacttacta ctgtcttatc tgatagcact gattagtgcg ggcgctggtt tttctttttt
    22441 tctctatttt ttggcatttg tgggacaaga atggatgatg gatcatattg taacagtgta
    22501 tttagtactc ttaagcttat tagttatgtt gattgttagt cgcttggaag agaaatttaa
    22561 gaaaggataa acgatgagac ttgaaattat aaatggacag aaaatttatg ggaaaagacc
    22621 tattttaaat cagttgaatt tggtgtttca atcaggaaaa atttatggac ttaaaggtga
    22681 taatggatct ggcaagacgg ttcttttaaa gatacttgct ggttatatta agcttgacaa
    22741 aggaaaagtt cttcaagatg gtaaagttta cggggtaaaa aatcattata ttcaggatgc
    22801 aggaatttta attgaaaaag tcgagttttt atctcattta tccctgagag aaaatttgga
    22861 actgttaagg tatttttcat ctaaagttac ggaaaaaaga attgcctatt ggattcaata
    22921 ctatgattta caggaatttg aagacgttga ataccgtcat ttatccttgg gaacaaagca
    22981 aaaaatggcc ttgattcaag cctttatttc ctctccttct atactctttc tcgatgaacc
    23041 tatgaatgct ttggatgaga agagtgtgag gttaaccaaa caggtcattt tatcttacct
    23101 gaaaaaagaa aatggtctgg ttatcctgac gtcgcacata tcggaagata tttcagacct
    23161 ttgtacagat gtattagttg tcgaaaatgg acatatacaa tatgtaaagg atatacaatc
    23221 ctaggagatg gcttatggca catctaaaat catttattac acgctattcc aaggtttata
    23281 ttggtttagt tctgctgatc tggctgtctt tcttctttat cccttgggat agagcgattc
    23341 tgggggtaag gattgacatc ttcatcatgc agaaaatctt gctagctttt ggaattctgt
    23401 ccattctcat ggccttgctg tccaagaaag tcagtctctt tgtttttgga ctgatttgct
    23461 gtctttctct ttggattaac ttatttatca catttgccat tttgccgatt tttggcaatt
    23521 aaacagtcat aaaagtcgga gaggttagct tgaaaactaa cctctttttc cttttcaaaa
    23581 tggggattct tccttgaaaa taatcagtaa ttgtgctaaa attaaaggaa cattctaaaa
    23641 tattcggaat ttaaagtaag gaaaaacatg gctaatattt taaaaacaat tatcgaaaat
    23701 gataaaggag aaatccgtcg tctggaaaag atggctgaca aggttttcaa atacgaagac
    23761 caaatggcta ctttgactga cgaccaacta aaagcaaaaa cagttgaatt taaggaacgt
    23821 tatcaaaatg gagaatcact ggattcattg ctttacgaag catttgcggt tgtccgtgaa
    23881 ggtgccaaac gtgtcctagg tctcttccct tataaggttc aggtcatggg ggggattgtt
    23941 cttcaccatg gtgacgtgcc agagatgcgt acaggggaag ggaaaacctt gactgcgacc
    24001 atgccggtat acctcaatgc cctttcaggt aaaggggttc acgtagttac ggttaatgaa
    24061 tacctgtcag aacgtgacgc gactgagatg ggtgaattgt actcttggct tggtttgtca
    24121 gtagggatta acttggctac caaatctcca atggagaaaa aagaagccta tgagtgtgat
    24181 attacttact caactaactc agaaatcgga tttgactacc ttcgtgacaa catggtcgtt
    24241 cgcgccgaaa acatggtaca acgtccgctt aactatgcct tggtcgatga ggttgactct
    24301 atcttgattg acgaggctcg tacacctttg attgtatcag gtgccaatgc ggttgaaacc
    24361 agtcagttgt atcacatggc agaccactat gtaaaatctt tgaacaaaga tgactacatc
    24421 atcgatgtgc agtctaagac tattggtttg tctgattcag ggattgacag ggctgaaagc
    24481 tacttcaaac ttgaaaacct ctatgacatc gaaaacgtgg ctttgactca ctttatcgat
    24541 aacgcccttc gtgccaacta catcatgctt ctcgatattg actatgtggt gagcgaagag
    24601 caagaaatct tgattgtcga ccaatttaca ggtcgtacca tggaaggtcg tcgttattct
    24661 gatggattgc accaagctat tgaagccaaa gaaggtgtgc caatccagga tgaaaccaag
    24721 acatctgcct caatcacgta ccaaaacctt ttccgtatgt acaagaaatt gtctggtatg
    24781 acgggtacag gtaagactga ggaagaagaa ttccgtgaaa tctacaacat tcgtgttatt
    24841 ccaatcccaa caaaccgtcc tgttcaacgt attgaccact cagaccttct ttatgcaagt
    24901 atcgaatcta agtttaaagc ggttgtcgaa gacgttaagg ctcgttacca aaagggtcaa
    24961 cctgtcttgg ttggtacagt agcggttgaa actagtgact acatttctaa gaaattggtt
    25021 gcagctggtg ttcctcacga agtcttgaat gccaaaaacc actatagaga agcccaaatc
    25081 atcatgaatg ctggtcaacg tggtgccgtt accatcgcaa ccaacatggc gggtcgtggt
    25141 accgacatca agcttggtga aggtgttcgt gaacttggag gactttgtgt tattggtaca
    25201 gaacgtcatg aaagtcgtcg tatcgataac cagcttcgtg gacgttcagg tcgtcaagga
    25261 gatccaggtg agtcacaatt ctacctatct cttgaagatg atttgatgaa acgttttggt
    25321 tctgaacgct tgaagggaat ctttgaacgt ttgaacatgt ctgaagaggc gattgagtct
    25381 cgcatgttga cgcgtcaggt tgaagcagct cagaaacgtg tcgaaggaaa taactacgat
    25441 acccgtaaac aagtccttca atacgatgat gtcatgcgtg aacaacgtga gattatctat
    25501 gctcaacgtt acgatgtcat cactgcagat cgtgacttgg cacctgaaat tcaggctatg
    25561 atcaaacgca cgattgaacg tgtcgttgat ggtcatgcgc gtgccaaaca agatgaaaaa
    25621 ctagaggcaa ttttgaactt tgctaagtac aacttgcttc ctgaagattc tattacgatg
    25681 gaagacttgt caggcttgtc tgataaggcc atcaaggaag agcttttcca acgtgccttg
    25741 aaggtttacg atagtcaggt ttcaaaacta cgcgatgaag aagcagttaa agaattccaa
    25801 aaagttttga ttctacgagt ggtggataac aagtggacag atcatatcga tgcccttgat
    25861 caattgcgta acgcggttgg acttcgtggc tatgctcaga acaaccctgt tgttgagtat
    25921 caggcagaag gtttccgtat gtttaatgat atgattggtt cgattgagtt tgatgtgaca
    25981 cgcttgatga tgaaagcaca aattcatgaa caagaaagac cacaggcaga acgtcatatc
    26041 agtacaacag cgactcgcaa tatcgctgct caccaagcaa gtatgccaga agatttggat
    26101 ttgagccaga ttggacgcaa tgaactttgc ccatgtggtt ctggtaagaa atttaaaaac
    26161 tgtcacggta aaagacaata aaatgagata gtttagaggc ggatatcttg tgaaaagtaa
    26221 atttttactg ggtatccgtt tgctttataa ggagatgagt tatggtattt acagcaaaaa
    26281 gctctaaaat aaatatagaa gaagttcgtg ccttgtcaaa attagaaggt caggctttgg
    26341 agaggaaatc acagcgcgat caagagctag aagccattat acgtggagaa gatcagcgaa
    26401 ttctcttggt aatcgggcca tgctcatctg acaacgaaga agctgtcctt gaatacgcta
    26461 agcgtttggc agtcctacaa gaagaagtgg cagatcgtat ctttatggtt atgcgtgttt
    26521 atactgccaa accccgtacc aacggagatg gctataaggg cttgattcac cagcctaacg
    26581 cgacagaagc gcctagtctt atcaatggaa tcaaagccgt tcgccatctt cactatcgtg
    26641 tcatcacaga aacagggatg acaactgctg atgaaatgct ttatcctgaa aaccttccgc
    26701 ttgtagatga tttgatttct tacatggcag ttggtgcccg ttcagttgaa gaccagcaac
    26761 accgctttgt ggcaagtggg gcaggatttt ctactggttt taaaaatcca acctctggaa
    26821 atctcaatgt catgtttaat gggatttatg ctgctcaaaa caaacaaagt ttccttttct
    26881 taggaaaaga agtagaaaca actgggaacc cgctttcaca cgctattctt cgtggtgctc
    26941 ttaatgagta tggaaaaaat attcccaact actattatga caatttaatt gataccattg
    27001 cccaatatga gaaaatgggc ttggaaaatc cttttatcat cattgatacc aatcatgaca
    27061 attctggtaa gcagtatatt gaacagatcc gaattgtccg ccagaccttg attaaccgtg
    27121 cttggaatga aaaaattaag cagttcgttc gtggttttat gattgagtct tatctggaag
    27181 atggtcgaca aaatgagcca gaagtatttg gcaagtctat cacagaccct tgcctgggtt
    27241 gggataacac agaagctctt gtcagagaaa tttacaaaac gttaggagaa taagatggca
    27301 tttattgaaa aaggtcaaga aatcgatatg gaagtcatca aggctgaaac ccaattgtct
    27361 gcggaagcct tgagactcaa ggaaagccgt gacagggaat tggcagatat tatttcaggg
    27421 gaagatgacc gtattctctt ggtgattggt ccttgctctt ctgataatga agaggcggtc
    27481 ttggaatatg ctcgccgttt atccgccttg caaaagaagg tagcggacaa gattttcatg
    27541 gtcatgcgcg tgtatactgc taagcctcgt accaatggag acggctataa aggattggtt
    27601 caccagccag atacttctaa ggctccaagc ctgattaacg gtttgcaggc tgtgcgccag
    27661 ttgcattacc gcgtgattac agagactggt ttgacaacgg cagatgagat gctttatccg
    27721 tcaaatctga tcttggtgga tgacttggtc agctaccatg ccgttggagc tcgttctgtg
    27781 gaagaccaag agcaccgctt tgtggcttct gggattgatg caccagtagg gatgaaaaat
    27841 ccaacctcag gaaatttggg tgttatgttt aacgccatct atgctgctca aaacaagcaa
    27901 accttccttt atcatgggca ggaagttgag acatcaggta atcctttggc ccatgttatc
    27961 ctccgtggag cagtcaacga gtatggcaat tatatgccga attactacta tgaaaaccta
    28021 ctccaagcca ttgaacgcta tgaaaccatg ggacttgaaa atccttttat cctcattgac
    28081 accaaccatg ataactcagg caagcaatat atggagcaga ttcgaattgt tcgccagacc
    28141 ttgcagaatc gtgattggaa tgagaaaatt aaaaagacgg ttcgaggatt tatgattgaa
    28201 tcttacctag cagatggtcg tcaaaaccaa ccagagatct ttggttgctc tattactgac
    28261 ccttgcctag gttgggaaaa tacagaggcc ttggtagaag agatttatgt taccttgaca
    28321 aaataagtga aaaggatgga gttggggaat ctcaactcct tttgatgaga atgatagttg
    28381 gacacggaat tgacatcgaa gaattggctt cgatagaaag cgcagttaca cgacatgaag
    28441 gatttgctaa gcgtgtactg accgctcagg aaatggagcg cttcaccagt ctcaaaggac
    28501 gcaggcaaat agaatattta gctggtcgct ggtcggctaa ggaggccttt tccaaggcta
    28561 tgggaacggg cattagcaag ctcggttttc aggatttgga agtattgaac aatgaacgtg
    28621 gggcgcctta ttttagtcag gcaccatttt caggaaagat ttggctgtct atcagccaca
    28681 ccgatcagtt tgtgacagcc agtgtcattt tggaggaaaa tcatgaaagc tagtccacat
    28741 agaccaacca aggctctgat tcatctggga gctattcgac aaaatattca gcaaatgggg
    28801 gctcatatcc ctcaaggaac gctcaagttg gctgtggtta aggccaatgc ttatggtcat
    28861 ggagctgttg ccgttgccaa ggcaattcaa gatgatgttg atggcttttg cgtttccaat
    28921 atcgatgaag ccattgaact cagacaagct ggactcagca agccaatcct cattttagga
    28981 gtttctgaaa tcgaagctgt tgctctagct aaagaatatg acttcacctt gacagtggct
    29041 ggactggagt ggattcaagc actcttagat aaggaagtgg acctaactgg attgacagtc
    29101 cacctcaaga ttgattcagg gatgggacgg attggtttta gagaggcaag tgaggttgag
    29161 caggctcaag atttgctcca acaacacggt gttcgtgttg aaggaatctt tacccacttt
    29221 gctactgctg atgaggaatc agatgactat tttaatgccc agttagaacg gtttaaaact
    29281 attttagcta gtatgaagga agttccagag ctggttcatg ctagcaattc tgcaacgact
    29341 ctttggcatg tagagactat tttcaatgcg gttcgtatgg gagatgccat gtatggtctc
    29401 aatccaagtg gagcggtctt ggctttgcct tatgatttga taccggcctt gaccttggag
    29461 tctgctctgg ttcatatcaa gacagttcca gctggtgctt gcatgggcta tggagcaact
    29521 tatcaaacgg atagcgagca agtcatcgcg accgtgccaa tcgggtatgc agatggatgg
    29581 acaagagaca tgcaaaattt ctctgtcttg gtagatggcc aagcttgccc aattgtcggc
    29641 agggtttcga tggaccaaat cactattcga ttgcctaagc cttacccact cggaaccaag
    29701 gtaaccttga ttggctccaa tggggataag gaaatcactg caactcaggt agcgacctac
    29761 cgcgtaacca ttaactatga ggtggtttgc ctcctcagcg accgtattcc gagagaatat
    29821 tactagaaaa gaaaggagtg gagcatgaat ctacatcaac ccttgcatgt cttgcctggt
    29881 gtgggaccaa agtcagcaga aaaatacgcc aaactaggaa ttgaaaactt gcaagatctc
    29941 ttgctctact ttcctttccg ttatgaagac ttcaaaatca agcaggtgct ggagctggaa
    30001 gacggtgaga aggcagttct ttctggtcag gtagtgactc ctgctagtgt ccagtattat
    30061 ggtttcaagc gcaatcgcct gcgttttagt ctcaagcagg gagaggtcgt ttttgcggtg
    30121 aatttcttta accagcccta tctggctgat aaaatagagt tgggagcaac ccttgctgtc
    30181 tttggaaaat gggaccgcgc taaggctagt ctgactggga tgaaggttct ggctcaggta
    30241 gaagatgacc tccagcctgt ctatcgtctg gctcagggaa tcagtcaggc cagtctggtt
    30301 aaggtcatca agacggcttt tgatcaggga ctggacctct tgatagaaga aaatctgccc
    30361 cagtctttac tagacaaata caaactcatg tcccgttgtc aggcagtccg agctatgcat
    30421 tttccaaagg atttggcaga atacaagcag gctcttcgcc gtatcaagtt tgaggaactc
    30481 ttttatttcc aaatgcagct gcagatgctc aagtctgaaa atagagttca gggaagtggt
    30541 ctggttctga attggtctca ggaaaaagtg acagcagtta aagtaagtct tccttttgcc
    30601 ctgacccaag ctcaggaaaa gagtttgcag gaaattttaa ctgatatgaa gtccgaccac
    30661 cacatgaatc gtctcctaca aggggatgtg gggagtggaa aaacggtagt cgctggcttg
    30721 gccatgtttg cggcagtgac agcaggttat caggctgccc taatggtacc aacagaaatc
    30781 ctcgcagagc aacactttga gagtttacag aacctttttc ccaatttgaa actggctctc
    30841 ttgacaggtt ccttgaaagc tgcagaaaag agagaggtct tggagaccat tgccaagggt
    30901 gaggctgatt tgattatcgg aactcacgct ctgatacaag atggggtgga gtatgctcgt
    30961 cttggtttga ttattatcga tgagcagcac cgttttggtg tagggcaaag gcgtatttta
    31021 cgggaaaaag gtgacaatcc agatgtcctc atgatgacgg cgactcccat tccacggacg
    31081 cttgccatca cagcctttgg agatatggat gtttccatta tcgaccagat gccagcaggt
    31141 cggaagccta ttgtgacgcg ctggatcaaa catgagcaac tacctcaggt cttgacttgg
    31201 ttagaggggg aaattcaaaa aggttcccaa gcctatgtca tctctccttt gattgaagaa
    31261 tcagaagctc tagatttgaa aaatgccatt gccttatcag aggagttgac gactcatttt
    31321 gcaggcaagg cagaggtggc tcttctacat ggtaggatga agagtgacga aaaagaccag
    31381 atcatgcagg atttcaagga gagaaagacg gatattctgg tttcgacgac ggttattgag
    31441 gttggggtca acgttcccaa tgcgactgtc atgattatca tggatgccga tcgcttcggt
    31501 ctcagtcaac ttcaccagct tagaggtcgt gtcggtcggg gggacaagca gtcctacgct
    31561 gttctcgttg ccaatcccaa gacggattct gggaaagacc gcatgcgtat catgacagaa
    31621 acgaccaatg gatttgtcct tgcggaggaa gatttgaaaa tgcgtggttc tggtgagatt
    31681 tttggaacca gacagtcagg acttccagag ttccaagtgg ctgatattat cgaagatttt
    31741 ccgattttag aagaagcaag aaaggttgct agctacatta gttctataga agcttggcaa
    31801 gaagatccag agtggcgcat gattgccctt catctggaaa agaaagaaca tctggattaa
    31861 gctttctcta aggaaaactt aagctagttt ttaggtttgg ctcttatact aaagtcatca
    31921 aaaagaaacg aggactctca tatgacagta acgattaaag taaattacca aaccactttc
    31981 caaaagaagg aagcaaaaaa ctagtataaa cagaagagag agcgaaatgc tctttttcgt
    32041 ttctaaaact actttcagcc catcatccta aaagtaaaga atctaaattc actttctatt
    32101 tatccttctt tcttgcattg attacataga tatgctacag ttgtggtaac gattacaaaa
    32161 taaaaggagc atgctatgaa aaatccagct ttgctagaag aaattaagac ctatagagga
    32221 agggatgagg ttccggaaga ctttgatgct ttctgggatg gggaagtgaa aaatgtttcc
    32281 acgcttccat cctaccactt ggaggaaaga gatttccaca ttcctcaagt caagtgctat
    32341 gagttaacat ttgaaggaag caaggaagga aaggtctatg cacgcattgt tcttccaaag
    32401 agtgaggaga aggttccact aatcttccat tttcatggtt atatgggacg tggctgggac
    32461 tgggccgaca tgctgggctt caccgtagct ggttacggtg ttgtttccat ggatgtgcgg
    32521 ggccagtcag gttactcaca agacggcttg cgttctcctt taggaaatac cgtgaagggg
    32581 catattatcc gtggtgctat ggaaggtcgg gaccacctct tttataagga tgtttatctg
    32641 gatatttacc agttggtcga aattgttgct agtctgtctc aggttgatga gaagcgtctt
    32701 tctagctatg gtgcctcaca aggaggggct ctagctctag ttgcagcagc gctcaatcct
    32761 cgaattcaga aaacagttgc catttatccc ttcttgtcag acttcagacg ggtgattgag
    32821 attggtaata ctagcgaggc ttacgacgaa cttttccgtt atttcaagtt tcacgacccc
    32881 ttccatgaaa cagaggagga aatcatggcg acccttgcct atatcgatgt caaaaatctt
    32941 gcccatcgta tccaaggtga ggttaagatg attacgggct tggacgacga tgtttgctat
    33001 cccattaccc agtttgcgat ttataatcgt ctgacctgcg ataaaaccta tcgcatcatg
    33061 cctgagtatg ctcacgaagc catgaatgta tttgtcaatg accaagtcta caactggctc
    33121 tgtggaagtg agattccttt taaatatcta aaataaggag tcgactctaa gcacaaaatc
    33181 ttaaaaatta caaacacgca tagtatcagg ggattaaaaa aacttgatac tatgcgtttt
    33241 atcatggaaa tatagtaaaa tgaaacaaga ataggacaaa acgatcagga cagtcaaatc
    33301 gatttctaac aatgttttag aagcaaatgt gtactattct agtttcaatc tattatattt
    33361 atagaatttt ttgttgctag atttgtcaaa ttgcttaaaa taattttttt cagaaagcaa
    33421 aagccgatac ctatcgagta gggtagttct tgctatcgtc aggcttgtct gtaggtgtta
    33481 atacttttca aaaatctctt taaaccacgt cagcttcgcc ttgccgtata tatgttactg
    33541 acttcgtcag ttctatctgc cacctcaaaa cggtgttttg agctgacttt gtcagtctta
    33601 tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt ttgctctttg
    33661 attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac tataaatgtt
    33721 cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa ctaaaatcta
    33781 ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt actaacgctt
    33841 ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg taaaaatagt
    33901 agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa ggggaataat
    33961 atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga actacttttg
    34021 acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg gattgtcccc
    34081 tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat ttctacaagt
    34141 atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc aggaagtatg
    34201 gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt tagtttaatt
    34261 gcagcggtgt cctggtagat aaactagatt ggcaggagtc tgattggaga aaggagaggg
    34321 gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt aaatgaactg
    34381 tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa atgtcttatt
    34441 tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtgtt caagaacgta
    34501 agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt gtaggagcag
    34561 tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa cctctggcaa
    34621 atgaaactca actttcgggg gagagctcaa ccctaactga tacagaaaag agccagcctt
    34681 cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat aagcaagaag
    34741 aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca gtgatagaaa
    34801 aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca agtgaactag
    34861 ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca gatgccaagg
    34921 ctccagcatt ctataatctc ttttctgtgt caagtgctac taaaaaagat gagtacttca
    34981 ctatggcagt ttacaataat actgctactc tagaggggcg tggttcggat gggaaacagt
    35041 tttacaataa ttacaacgat gcacccttaa aagttaaacc aggtcagtgg aattctgtga
    35101 ctttcacagt tgaaaaaccg acagcagaat tgccaaatgg tcgagttcgc ctgtatgtta
    35161 atggtgtttt atctcgaaca agtctgaaat ctggcaattt cattaaagat atgccagatg
    35221 taacgcatgt gcaaatcgga gcaaccaagc gtgccaacaa tacggtttgg gggtcaaatc
    35281 tacagattcg gaatctcact gtgtataatc gtgctttaac accagaagag gtacaaaaac
    35341 gtagtcaact ttttaaacgc tcagatttag aaaaaaaact acctgaagga gcggctttaa
    35401 cagagaaaac ggacatattc gaaagcgggc gtaacggtaa accaaataaa gatggaatca
    35461 agagttatcg tattccagca cttctcaaga cagataaagg aactttgatc gcaggtgcag
    35521 atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc agacgtagtg
    35581 aagataatgg taaaacttgg ggtaaccgag taaccattac caacttacgt gacaatccaa
    35641 aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg gttcaagatc
    35701 ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag ggaatctttg
    35761 gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc tatcaaatcc
    35821 tctatcgtga aggagaaaag ggagcttata ccattcgaga aaatggtact gtctatacac
    35881 cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca gcctatagcg
    35941 acaagggtga tctatacaag ggtaaccaat tactaggcaa tatctacttc acaacaaaca
    36001 aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac agtgatgacg
    36061 acgggaagac atggtcagcg cctcaagata ttactccgat ggtcaaagcc gattggatga
    36121 aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct cacaagggac
    36181 ggattttgat accggtttat acgactaata atgtatctca cttaaatggc tcgcaatctt
    36241 ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa gcggtcaacg
    36301 ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat agacgtgcgc
    36361 aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc tttatgcgtg
    36421 gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact tgggagaagg
    36481 atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct atccatacga
    36541 tgcataatgg aaaagaatac attatcctca gcaatgcagg tggaccgaat cgtgaaaatg
    36601 ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc aaacacaatc
    36661 caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat ggggagtatg
    36721 gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca tttagaaaat
    36781 ttaattggga atttttgagc aaagatctga tttctcctac cgaagcgaaa gtgaagcgaa
    36841 ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag tttgactcag
    36901 aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca gcgactttcc
    36961 taacccagta tgatagcaaa accttgttgt ttgcagtaga taaggaagat atcggacagg
    37021 aaattattgg tatagctaaa ggaagcatcg aaagtatgca taatcttcct gtaaatctag
    37081 caggtgccag agttcctggc ggagtaaatg gtagcaaagc agcggtgcat gaagttccag
    37141 aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca gagtataagg
    37201 gatctgattc gcttgtaact cttactacaa aagaagatta tacttacaaa gctcctcttg
    37261 ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct tcactaggac
    37321 taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa taagagaaga
    37381 attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa gcctgctatc
    37441 tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact actttcagag
    37501 tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct atcaggaaag
    37561 tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga ttcaatatat
    37621 tatgtgacta ttaaccttct cttctcctaa aattgacttt cttgttttct tatcttgtcc
    37681 actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa tatacttgat
    37741 atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa atactaaaaa
    37801 aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg aaatatagag
    37861 tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt agccaaagag
    37921 tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg agcagcttat
    37981 aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa agggcgactt
    38041 ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa cttatttatt
    38101 ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac tgaatgaaaa
    38161 tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcctt gaggttgtag
    38221 ataagactga cctatataat ccaaggtgaa gcgactgtgg tttgaagaga ttttcaaaga
    38281 gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag acagaagaat
    38341 ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg attattacaa
    38401 aaattagcca tttaggaact tatgtgggag taaatccaca ttttgcaaca ttaatagatt
    38461 ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc gatggtaatc
    38521 gattgtttgg gaattgcttt acttatctag cagatggtca agcaggggct ttctttgaaa
    38581 cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc atggctgtta
    38641 catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat attgaattat
    38701 acacagggaa agtggaacag ttggttcagt tgagagctgg cgaatgcctc atcacttttc
    38761 cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa aaagttgtct
    38821 ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg agaaagtttt
    38881 tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca ggaaaaaaag
    38941 aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca atgtggcact
    39001 cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct ttcatgcaaa
    39061 agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc tatactaaat
    39121 ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt cctaaccaag
    39181 taatggaaat ggtcaactca gatgctttgg ttccgctaaa tgattctatc aagcgtattg
    39241 gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat gattactact
    39301 ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg ttaaaagaac
    39361 ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa aaattgaaag
    39421 aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg gcaacacgtt
    39481 tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat cttaaagcag
    39541 acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg tataaagaaa
    39601 tctcacctca agattctttg aactttaatg tccttcaaca agctaccttg ttctatcaag
    39661 gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat gccaacagtc
    39721 ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag tctgataaag
    39781 accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca aaacatccag
    39841 aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt aaattccttg
    39901 attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct gcagcctata
    39961 aagaaaatga aactcgtaag aagtttaaac atgctgaaga agtaattact gaagctgtta
    40021 aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt atgttgacta
    40081 accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca gatcctatga
    40141 aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt cagtagatgt
    40201 aaaagactag aaaataggtg ggctagtgag ctgaaaagct ctagcccaat cttgtaaaag
    40261 aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt gttttgccag
    40321 ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt ttttatagct
    40381 ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct aactataaag
    40441 ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag tggaccgttt
    40501 tctcattagt tggtcaagtt ttagtagggt ttgtattggc tttagctctt cacagagtac
    40561 gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt cctaccatcg
    40621 ttattgcctt ttcttggcag tggattctaa acggggttta tggctactta cctaatctaa
    40681 tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt acatgggcat
    40741 tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg gttaatgtgc
    40801 tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata gatggtgctt
    40861 caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt gtaggacttc
    40921 tagttgtttt gagaactgta tggatcttta ataactttga cattatctac ctcattactg
    40981 gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac ctgggctggg
    41041 gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc ttcttggtgg
    41101 cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt agaaaataat
    41161 gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag ttggtgcgac
    41221 catcgttgca attttcccat tggtatggat tatcatatct tctgtcaaag ggaaagggga
    41281 attaactcag tatccaacac gattttggcc tgaacagttt acattagatt atttcactca
    41341 tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca ttgccttggc
    41401 tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg ttcgattctt
    41461 tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctacattt tcccaccaat
    41521 tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa atagtttatt
    41581 tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc tcttagttgg
    41641 atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg gtgcaaataa
    41701 atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg tagcaacagc
    41761 tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt tgattaacaa
    41821 tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag aaatactaga
    41881 ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta ttttcttctc
    41941 tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt agacgaaaga
    42001 aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt tgtaggcatt
    42061 agtcttttaa tgggagtccc cactttgatt catgcgaatg aattaaacta tggtcaactg
    42121 tccatatctc ctatttttca aggaggctca tatcaactga acaataagag tatagatatc
    42181 agccctttgt tattagataa attgtctgga gagagtcaga cagtagtaat gaaatttaaa
    42241 gcagatgaac caaactctct tcaagctttg tttggcctat ctaatagtaa agcaggcttt
    42301 aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt agaaataaga
    42361 gacgcccaaa agggaataaa ttatttattt tccagaccag cttcattatg gggaaaacat
    42421 aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga taaaacatac
    42481 acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt tttgccaatt
    42541 tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga aggcaaggaa
    42601 cattacctcg caaaaagaag tattgatgaa atcagtctat ttaacaaagc aattagtgat
    42661 caggaagttt caaatattcc cttgtcaaat ccatttcagt taattttcca atcaggagat
    42721 tctactcaag ctaactattt tagaataccg acactatata cattaagtag tggaagagtt
    42781 ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa gattaatatt
    42841 gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt tgctatgaag
    42901 tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt aaagaatagt
    42961 caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa aaaatctggg
    43021 aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa tgcaaataaa
    43081 gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa gaagaatgga
    43141 gataacgatt tccgttatac agttagagaa aatggtgtcg tttatgatga aacaactaat
    43201 aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg aaagtcttta
    43261 acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaag gcataatgga
    43321 aaacaggttc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac tcctactaat
    43381 tatatagcaa tgacaactag tcagaataga gaagagagtt gggaacaatt taagttgttg
    43441 cctccgttct taggagaaaa acataatgga acttacttgt gtcctggaca aggtttagca
    43501 ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact aacctatctc
    43561 atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc gtttaaaaat
    43621 gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac attctttaga
    43681 accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac atggtcggaa
    43741 gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc tgcaattaaa
    43801 tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa ttctagaagt
    43861 ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga tagtattgat
    43921 tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc tgcgattaca
    43981 gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg gtcgagaaat
    44041 gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga tttaacaaaa
    44101 taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt ggagctgaat
    44161 tggctcgcta catgcaaaag aatgatggag cagagattac tcttctctat gatccagata
    44221 atgcagaggc gattgcagaa gaattgggag caaaagtagc aagttcctta gatgagttgg
    44281 tttctagcga tgaagtagat tgtgttatcg tcgcaactcc aaataatctt cataaggaac
    44341 cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca attgcgcttt
    44401 cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta acctttatgg
    44461 caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc attaatcaag
    44521 gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa gaacaacaac
    44581 cgtcagtgtc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat caccacatcc
    44641 atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta accatgacag
    44701 gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg atttttgtca
    44761 atatggaatt ttctaataag cgttttgcct tgttagaatg gggttcagct tatcgttggg
    44821 gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac ttattcaact
    44881 gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac gaatcgcaag
    44941 aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga gcaattgctt
    45001 atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat aaagaaatgc
    45061 gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca aaacttttga
    45121 caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag tctatgtttg
    45181 aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc tcctatttat
    45241 aggtcgactt gctcctctga aagtactttt agaggagctg tttgactttg ctagtttttg
    45301 aaactgaaat ctattatact acaaactatt gaaagcgttt taattttaag gtataataat
    45361 ctcatagaaa taaagaaaag gaggaaagag gatgccacag attagcaaag aagccttgat
    45421 tgagcaaatc aaagatggaa tcatcgtttc ttgtcaggct cttcctcatg aaccgcttta
    45481 tacagaagcg ggaggggtga ttcccttgct ggtcaaagcg gctgagcaag gtggagcagt
    45541 cggtatccga gcaaacagtg ttcgcgatat caaggaaatt aaggaagtca ctaaacttcc
    45601 aatcattggg attatcaaac gtgattatcc acctcaggaa cccttcatca cggctactat
    45661 gaaagaagtt gatgaattgg cagaactgga catcgaggtg attgctctgg attgtaccaa
    45721 gcgtgaacgc tacgatggtt tggaaattca agagttcatt cgtcaggtta aggagaaata
    45781 tcctaatcag cttttgatgg ctgatactag tatcttcgaa gaagggctag cagctgtaga
    45841 agcaggaatt gactttgtcg gaacaacctt atcaggctac acatcctaca gtccaaaagt
    45901 agacggtcca gattttgaat tgattaagaa actctgtgat gccggtgtag atgtcattgc
    45961 agaaggaaaa attcatacac cagaacaagc caaacaaatc cttgaatatg gagtgcgagg
    46021 catcgttgtt ggtggcgcca ttactagacc aaaagagatt acagaacgct tcgttgctag
    46081 tcttaaataa gatgtgaggg ggagttttat gtttaaagtt ttacaaaaag ttggaaaagc
    46141 ttttatgtta cctatagcta tacttcctgc agcaggtcta cttttgggga ttggtggtgc
    46201 actttcaaac ccaaccacga tagcaactta tccaatacta gacaatagta tttttcaatc
    46261 aatattccaa gtaatgagct ctgcaggaga ggttgtattc agtaatttgt cactacttct
    46321 ctgtgtggga ttatgtattg gcttagcgaa acgagataaa ggaaccgctg cgttagcagg
    46381 agtaactggt tacttagtta tgactgcaac gatcaaagct ttagtaaaac tttttatggc
    46441 agaaggatct gcaattgata ctggagttat tggagcatta gttgtcggaa tagttgccgt
    46501 atatttgcac aaccgatata acaatattca attaccttcc gctttaggat tctttggagg
    46561 ttcacgcttc gttcctattg ttacatcgtt ctcttctatc ttgattggct ttgtcttctt
    46621 tgttatttgg ccacctttcc aacaacttct tgtttctaca ggtggatata tttctcaggc
    46681 gggtccaatt ggaacttttc tatatggatt tttaatgaga ctttctggag cagtaggctt
    46741 acatcatata atttacccta tgttttggta tactgaactt ggtggtgttg aaactgttgc
    46801 aggacaaaca gtggttggag ctcaaaaaat attttttgct caattagccg atttggccca
    46861 ttctggatta tttacagaag gaacaaggtt ttttgcaggt cgtttctcaa caatgatgtt
    46921 cggtttaccg gctgcctgtt tagcgatgta ccatagtgtt cctaaaaatc gtcgtaaaaa
    46981 atacgcgggt ttgtttttgg gagttgcttt aacatctttt attaccggta ttacagaacc
    47041 aattgaattt atgtttctat tcgttagtcc ggttctatat gttgttcacg cattccttga
    47101 tggtgttagc ttctttattg cagacgtctt aaatatttca ataggaaaca cattttcagg
    47161 aggtgtaatc gatttcactt tatttggaat tttgcagggg aacgctaaga cgaattgggt
    47221 tcttcagatt ccatttggac ttatttggag tgttttgtat tatattattt ttagatggtt
    47281 cattactcaa ttcaacgttc taacgccagg gcgaggagaa gaagtagatt ctaaagaaat
    47341 ttctgaatcc gcagattcaa cttcaaatac tgcagattat ttaaaacagg atagcctaca
    47401 aattatcaga gccttgggtg gatcaaataa tatagaagat gtagatgctt gtgtgacacg
    47461 tttacgtgta gctgtaaaag aagttaatca agttgataaa gcacttttaa aacaaattgg
    47521 tgcagttgat gtcttagaag tgaagggtgg cattcaagca atatatggag caaaagcaat
    47581 cttatataaa aatagtatta atgaaatttt aggtgtagat gattaagtac ttactgactt
    47641 aataaaaaac agaggagagt gatggatgag taggatgaaa tgaaatcgca tacaagaaat
    47701 aaagaactca ttatccaagt tggatacgct tattacatag gagaatacaa atgaaattta
    47761 gaaaattagc ttgtacagta cttgcgggtg ctgcggttct tggtcttgct gcttgtggca
    47821 attctggcgg aagtaaagat gctgccaaat caggtggtga cggtgccaaa acagaaatca
    47881 cttggtgggc attcccagta tttacccaag aaaaaactgg tgacggtgtt ggaacttatg
    47941 aaaaatcaat catcgaagcg tttgaaaaag caaacccaga tataaaagtg aaattggaaa
    48001 ccatcgactt caagtcaggt cctgaaaaaa tcacaacagc catcgaagca ggaacagctc
    48061 cagacgtact ctttgatgca ccaggacgta tcatccaata cggtaaaaac ggtaaattgg
    48121 ctgagttgaa cgacctcttc acagatgaat ttgttaaaga tgtcaacaat gaaaacatcg
    48181 tacaagcaag taaagctgga gacaaggctt atatgtatcc gattagttct gccccattct
    48241 acatggcaat gaacaagaaa atgttagaag atgctggagt agcaaacctt gtaaaagaag
    48301 gttggacaac tgatgatttt gaaaaagtat tgaaagcact taaagacaag ggttacacac
    48361 caggttcatt gttcagttct ggtcaagggg gagaccaagg aacacgtgcc tttatctcta
    48421 acctttatag cggttctgta acagatgaaa aagttagcaa atatacaact gatgatccta
    48481 aattcgtcaa aggtcttgaa aaagcaacta gctggattaa agacaatttg atcaataatg
    48541 gttcacaatt tgacggtggg gcagatatcc aaaactttgc caacggtcaa acatcttaca
    48601 caatcctttg ggcaccagct caaaatggta tccaagctaa acttttagaa gcaagtaagg
    48661 tagaagtggt agaagtacca ttcccatcag acgaaggtaa gccagctctt gaataccttg
    48721 taaacggatt tgcagtattc aacaataaag acgacaagaa agtcgctgca tctaagaaat
    48781 tcatccagtt tatcgcagat gacaaagagt ggggacctaa agacgtagtt cgtacaggtg
    48841 ctttcccagt ccgtacttca tttggaaaac tttatgaaga caaacgcatg gaaacaatca
    48901 gcggctggac tcaatactac tcaccatact acaacactat tgatggtttt gctgaaatga
    48961 gaacactttg gttcccaatg ttgcaatctg tatcaaatgg tgacgaaaaa ccagcggatg
    49021 ctttgaaagc cttcactgaa aaagcaaacg aaacaatcaa aaaagctatg aaacaatagt
    49081 ccttagttat tctataaaaa gtagtttttt aaagaaccta agagtgtata cccccttttc
    49141 cctctacaca gatagtgtaa gaaaaggggg cttttgttta aaatgtaaga aactgtcacg
    49201 aaattaaaat gaagttctta cataagcgaa tcataaaaaa tttcattttg attttaaaac
    49261 agttcaagaa agtcaaaaaa ttattctatt tgaaagagag gtgccgactg tgaaagtcaa
    49321 taaaatccgt atgcgggaaa cagtgatttc ctacgctttc ctagcaccag tattattctt
    49381 ctttgtcatc tttgtgttgg ctccgatggt gatgggcttc attacaagtt tctttaacta
    49441 ctcaatgact aaatttgagt ttgtaggctt ggataactat atccgtatgt ttaaagatcc
    49501 tgtctttaca aaatctctga ttaacacagt tattttggtt attggatctg taccagttgt
    49561 tgttctattc tcactctttg tagcatctca gacctatcat caaaatgtca ttgccagatc
    49621 cttctaccgt ttcgtcttct tccttcctgt tgtaacgggt agtgttgccg tgacagttgt
    49681 ttggaaatgg atttatgacc cactatcagg gattctaaac tttgtcctta agtccagcca
    49741 catcatcagc caaaacattt cttggttggg agataaaaac tgggcattga tggcgattat
    49801 gattattctc ttgaccactt cagttggtca gcccatcatc ctttatatcg ctgccatggg
    49861 gaatattgac aattcactgg ttgaagcggc gcgtgttgat ggtgcaactg agtttcaagt
    49921 tttttggaag attaaatggc caagccttct tccaacaact ctttatattg caatcatcac
    49981 aacaattaac tcattccagt gtttcgcctt gattcagctt ttgacatctg gtggtccaaa
    50041 ctactcaaca agtaccttga tgtactacct ttacgaaaaa gccttccaat tgacagaata
    50101 cggctatgcc aacacaattg gtgtcttctt ggcagtcatg attgctatcg taagctttgt
    50161 tcaatttaaa gtacttggaa acgacgtaga atactaaaga aaggagacag ctatgcaatc
    50221 tacagaaaaa aaaccattaa cagcctttac tgttatttca acaatcattt tgctcttgtt
    50281 gactgtgctg ttcatctttc cattctactg gattttgaca ggggcattca aatcacaacc
    50341 tgatacaatt gttattcctc ctcagtggtt ccctaaaatg ccaaccatgg aaaacttcca
    50401 acaactcatg gtgcagaacc ctgccttgca atggatgtgg aactcagtat ttatctcatt
    50461 ggtaaccatg ttcttagttt gtgcaacctc atctctagca ggttatgtat tggctaaaaa
    50521 acgtttctat ggtcaacgca ttctatttgc tatctttatc gctgctatgg cgcttccaaa
    50581 acaagttgtc cttgtaccat tggtacgtat cgtcaacttc atgggaatcc acgatactct
    50641 ctgggcagtt atcttgcctt tgattggatg gccattcggt gtcttcctca tgaaacaatt
    50701 tagtgaaaat attcctacag agttgcttga atcagctaaa atcgacggtt gtggtgagat
    50761 tcgtaccttc tggagtgtag ccttcccgat tgtgaaacca gggtttgcag cccttgcaat
    50821 ctttaccttc atcaatactt ggaatgacta cttcatgcag ttggtaatgt tgacttcacg
    50881 taacaatttg accatctcac ttggggttgc gaccatgcag gctgaaatgg caaccaacta
    50941 tggtttgatt atggcaggag ctgcccttgc tgctgttcca atcgtcacag tcttccttgt
    51001 cttccaaaaa tccttcacac agggtattac tatgggagcg gtcaaaggat aatactctgc
    51061 gaaaatcgaa tgcaaactac gtcagcttca ccttgccata cttaagtatt gcctgcggtt
    51121 agcttcctag tttgttcttc aattttcatt gagtatagga aaatcaatct atcaagatac
    51181 agaagtatat tttatagatt tagagaatat agaagttata agtgtctaca aaatggaggg
    51241 tatgcagtta ctttatgaag ttttgtcaga cacttatcaa cttaagaatg attttagtta
    51301 attatcagaa acgaaggaaa gagtatgatt tttgacgatt tgaaaaacat caccttttac
    51361 aaagggattc atcccaattt agacaaagct atcgactacc tctaccaaca tcgtaaagat
    51421 tcattcgaat taggaaagta tgagattgat ggagataagg tctttctagt tgttcaggaa
    51481 aatgtcctca atcaagttga gaataatcaa tttgaacacc ataagaacta tgcagatttg
    51541 catttgctga tagaagggca tgaatattcg agctacggtt cacgtatcaa agacgaggca
    51601 gtagcattcg acgaagcgac tgacattggc tttgttcatt gtcatgaaca ctacccactc
    51661 ttgttgggtt atcataattt tgcgattttc ttcccaggtg agccacatca gccaactggc
    51721 tatgcaggta tggaagaaaa ggttcgaaaa tatctcttta aaattttgat tgattaaaaa
    51781 taggatgaat tgtttttttg taaagctttg acaatactct accatgaaat tgatctttat
    51841 gaggtagaga aatgagaata aaatatttaa aaattggtat cttctaagca tgctgcaaga
    51901 gctagtttct tagatggaca ggaaattaca gttgatgaga tgtcctggat aattaatggc
    51961 attgtgaatg cattgattgg tagatacata aaattaggta cttatgcagc taagtatggt
    52021 attggtatag cacgctcgat cttaagtagg gcagctgcaa ctgcagcagc aagagtagga
    52081 ttactgacca agatttctgg atggatttta cgagtagctg tgaatgtagc tgatgtatat
    52141 ggtaatttcg ccaacaatat tgctgcagct tgggatgcat atgataaaat tcctaacaat
    52201 ggtcgtataa acttttaaaa tacgagaatg aaagcacttt gtattttttt attgaatatg
    52261 ttagcttgga cagtgcttgc aatgataatt cgtggagggc tagatggatt tgataggcat
    52321 acttggagta ctattttaat tgcttcgctg ttcggggtat atgattataa gcccatagat
    52381 aaaaatagaa aaaagtccaa aagaaaaaag aaaaaataga tttgttcatg gtagggactt
    52441 atgaaagctt tactgacaaa aaagaaaaca gtttacaaag aaaaatgatg gaggagcaaa
    52501 catggcacaa aaaggagtaa gccttatcaa ggcagcattt gatacagata actttctcat
    52561 gcgttttagt gagaaggtct tggacatcgt gacagccaat cttctttttg tcgtctcttg
    52621 tttacccatc gtgacgattg gagtggctaa aatcagcctc tacgagacca tgttcgaagt
    52681 taagaagagc agacgggtgc ctgtttttaa aatctatcta agatctttca agcaaaatct
    52741 gaaactaggt cttcagctgg gtttaatgga gttaggaatt gtgtttctta ccctttcaga
    52801 tctctatctt ttctggggtc aaacagctct gcccttccaa ttgctgaaag ccatttgttt
    52861 aggtattctg atttttctta ctatcgtgat gctggctagt taccctatcg cggcacgtta
    52921 tgacctatct tggaaagaaa ttcttcaaaa aggattgatg ttggctagtt ttaactttcc
    52981 ttggttcttc ctcatgttag ccattcttgt cctcattgtg atggttcttt atctgtccgc
    53041 cttcagtcta ctcttaggtg gctcagtctt cctacttttt gggtttggac tattggtctt
    53101 tatccagact ggattgatgg agaaaatttt cgcaaaatac caataggagc tttatttctg
    53161 aaactacttt caaaggctcc aaacgctatt ctataagcga gaaactaaaa tctaagtgtc
    53221 tataagatat tgaaagcctt ttcggtaaag tgtatactaa agaagtaaag aaaaatctgc
    53281 tttagcagaa aataaaaata ataggagaaa atctatgtca gatttgaaaa aatacgaagg
    53341 tgtcattcca gccttctacg catgttatga tgagcaagga gaagtaagtc cagagcgtac
    53401 gcgtgccttg gttcaatact tcattgataa aggtgttcaa ggtctttatg tcaatggttc
    53461 ttctggtgaa tgtatctacc aaagcgttga agatcgcaag ttgattttgg aagaagtcat
    53521 ggcggtagct aaaggtaaat tgaccattat tgcccatgtt gcctgcaaca atactaaaga
    53581 cagtatggaa cttgctcgcc atgctgaaag cttgggagta gatgctattg caacgattcc
    53641 accaatttat ttccgcttgc cagaatactc agttgccaaa tactggaacg atatcagttc
    53701 tgcagctcca aacacagact acgtgattta caacattcct caattggcag gggttgcttt
    53761 gactccaagc ctttacacag aaatgttgaa aaatcctcgt gttatcggtg tgaagaactc
    53821 ttctatgcca gttcaagata tccaaacctt tgtcagcctt ggtggggaag accatatcgt
    53881 ctttaacggt ccagatgaac agttcctagg tggtcgcctc atgggtgcca aagctggtat
    53941 cggtggtact tatggtgcta tgccagaact cttcttgaaa ctcaaccaat tgattgcgga
    54001 taaagattta gaaacagcgc gtgagttaca gtatgctatc aacgctatca ttggtaaatt
    54061 gactgctaca catggaaata tgtacggtgt catcaaagaa gttttgaaga tcaatgaagg
    54121 cttgaatatt ggttctgttc gttcaccatt gacaccagtg actgaagaag atcgtccagt
    54181 tgtagaagcg gctgctgcct tgattcgtga aaccaaggag agcttcctct aatctaaaag
    54241 gaggtattta tgacatacta cgttgcaatt gatatcggtg gaaccaacat caagtatggt
    54301 ttggttgatc aagaggggca acttcttgaa tcgcatgaaa tgccaactga ggcgcataag
    54361 ggtggacctc atatcttaca aaagaccaaa gatatcgtag ctagttattt agaaaaaggc
    54421 ccagtagcag gtgttgccat atcttctgct gggatggtgg atccggataa gggtgagatt
    54481 ttctatgctg ggccgcaaat ccctaactac gcaggcaccc agttcaaaaa ggaaatcgaa
    54541 gaaagcttta ctattccttg tgagattgaa aatgatgtca actgtgcagg tcttgctgag
    54601 gcagtatctg gttcaggcaa gggagcaagt gtgacacttt gcttgaccat tggaaccggt
    54661 atcggtggtt gcttgattat ggataggaaa gtcttccatg gttttagcaa ttcagcctgt
    54721 gaagtcgggt atatgcatat gcaggatgga gcttttcaag acttggcttc tacaacagct
    54781 ttagtgaaat atgtagctga agcccatgga gaagatgttg atcagtggaa tggccgtaga
    54841 attttcaaag aagccactga aggaaacaaa atctgcatgg aaggtattga ccgtatggtt
    54901 gactatctag gaaaaggtct ggcaaatatt tgctacgttg ccaatccaga agtggttatt
    54961 cttggtggtg gtatcatggg gcaagaggct atcctcaaac ctaagatccg cacagccttg
    55021 aaagaggctt tggtaccaag tttagcagaa aaaacacgat tagaatttgc ccatcaccaa
    55081 aatacagcag ggatgttggg tgcatattat cattttaaga caaaacaatc ctagtttggc
    55141 tcagccaaac taggattttc ttacacgttt ttgtctacga tagccgttga gttttttatt
    55201 ttcccagtag ctattaaaga ttttttcctt gctttcgcga ttgatttcca aaaagtaggc
    55261 ataaatcaaa tcgataaaga agagcatagg aagttgagcg gatattcgtt ggatatagga
    55321 gggttggctg tgggtggcta caagaacagt ctctgtatag gtctggctat ctttattggg
    55381 aacacttgta aagagtacag tctttgcccc catctccttg gcatctaata gactatctaa
    55441 aatagaagga gttgagcctg aaagtgagaa gcccagtact agacaatttt catccatgat
    55501 gctggttgtc caggcaaagc cgtcttggtc tgtcaaagct tcgcagacca cacctagtcg
    55561 cataaaacgt aatttcattt cacgggcgac gaggccagaa ctccctgttc caaagaagta
    55621 gatacgctca gcatcttcga ttagctgggc aattcgctct agttggattt cgtcaatcaa
    55681 gtcttgtgtt tgttccctca tattgctata acttctgagg actcgtttgg tcagtggact
    55741 gtgcttggag actcggttgg cttgattttc tgcctgatgt tggtattgga aaataaattc
    55801 tcggtagcca gtaaagccac actttttagc aaagcgggtc aaagcagctt gagaaatatg
    55861 taatttttgg gtgacttgtt gagaagataa atcatctgta atcgtttcag cttgcaaaaa
    55921 atagcgagcg atttcttgct ctaggtctgt catttcttca aaatgtgaat caatgatagt
    55981 tgcgatatct ggtttgtcca tagggaaagc tcctttacat gagtcatact ggaagactag
    56041 atcagggaat agtcacactt cattataaca cataatataa ggatagataa ataaaaacgc
    56101 atctctgttt taaaaacgaa aaaatcgaaa aagcttctct cttttccata attttctact
    56161 caaattgtgg tacaattaag agtaagattt taagttagaa atgagactga tttgtatgag
    56221 aaaatttaac agccattcga ttccgattcg gcttaattta ttgttttcaa tcgtcatttt
    56281 actctttatg accattattg gtcgtttgtt gtatatgcag gttttgaaca aggattttta
    56341 cgaaaaaaag ctagcctcag ctagtcagac caagattaca agcagttcag cccgtgggga
    56401 aatttatgat gctagtggaa aacctttggt agaaaatacg ttaaagcagg ttgtttcctt
    56461 tacgcgtagc aataaaatga cggctacaga cttaaaagaa acagctaaaa agttactgac
    56521 ttatgtgagc atcagttctc caaatttgac aaaacgccag ctggcggatt actatttggc
    56581 tgatcctgaa atctataaaa aaacagtgga agctctccca agcgagaaac gcttggattc
    56641 agatggcaat cgtctatccg aatcagaact gtataacaat gcggtcgata gtgtccaaac
    56701 aagtcaacta aactatacag aggatgaaaa gaaagaaatc tatcttttta gtcagttaaa
    56761 tgctgttgga aactttgcga caggaaccat tgctacagat cctctaaatg attctcaggt
    56821 ggctgttatt gcctctattt caaaggagat gcctggcatt agtatttcta cttcttggga
    56881 tagaaaggtt ttggaaactt ccctttcttc tatagttggg agtgtatcca gtgaaaaagc
    56941 tggtctccca gcggaagaag cagaagccta tcttaaaaaa ggctattctc taaatgaccg
    57001 tgtaggaacc tcctatttgg aaaagcaata tgaagagacc ttacaaggaa aacgatcggt
    57061 aaaagaaatc catctggata aatatggcaa tatggaaagc gtggatacaa ttgaggaagg
    57121 tagtaaggga aacaatatca aactgaccat tgatttggcc ttccaagata gcgtggatgc
    57181 tttgctgaaa agttatttca attctgagct agaaaatggt ggagccaagt attctgaagg
    57241 tgtctatgca gtcgccctta acccaaaaac aggtgcggtt ttgtctatgt cagggattaa
    57301 acatgacttg aaaacgggag agttgacgcc tgattccttg ggaacggtaa ccaatgtctt
    57361 tgttccaggt tcggttgtca aggcggcgac catcagctca ggttgggaaa atggagtctt
    57421 gtcaggaaac cagaccttga cagaccagtc cattgtcttc caaggttcag ctcccatcaa
    57481 ttcttggtat actcaggctt acggttcatt ccctatcaca gcggtccaag ctctggagta
    57541 ttcatcaaat acctatatgg tccaaacagc cttaggtctt atggggcaaa cctatcaacc
    57601 caatatgttt gtcggcacca gcaatctaga gtctgctatg gagaaactgc gttcaacctt
    57661 tggcgaatat ggcttgggta ctgcgacagg aattgaccta ccagatgaat ctactggatt
    57721 tgttcccaaa gagtatagct ttgctaatta cattactaat gcctttgggc agtttgataa
    57781 ctatacgccg atgcagttgg ctcagtatgt agcaactatt gcaaataatg gtgttcgtgt
    57841 ggctcctcgt attgttgaag gcatttatgg taataatgat aagggaggac tgggtgactt
    57901 gattcagcaa ctgcaaccga cagagataaa taaggtcaat atatccgact ccgatatgag
    57961 catcttgcac caaggttttt atcaggttgc ccatggtact agtggattga caactggacg
    58021 tgccttttca aatggtgcct tggtatccat tagcggaaaa acaggtacag ccgaaagcta
    58081 tgtggcagat ggtcagcaag caaccaatac caatgcggtg gcctatgccc catctgataa
    58141 tccccaaatc gctgtcgcag tggtctttcc tcataatacc aatctaacaa atggtgtagg
    58201 accttccatt gcgcgtgaca ttatcaatct gtatcaaaaa taccatccaa tgaactagaa
    58261 aggaaattat gctttatcca acacctattg ccaagttgat tgacagttat tctaagttac
    58321 caggtatcgg gattaagacg gctacgcgtc tggcctttta tacgattggg atgtctgctg
    58381 atgatgtcaa tgaatttgca aaaaatctcc tttctgctaa gagagaattg acatattgtt
    58441 ctatttgtgg acgtttgaca gacgacgatc cttgttctat ctgtactgat ccgactcgtg
    58501 accagacaac aattttagtt cttgaggata gtagagatgt ggcagccatg gaaaatatcc
    58561 aagaatacca tggactctat catgtcctgc atggcctcat ttctcctatg aatggtatca
    58621 gtccggacga tatcaatctc aagagcctta tgactcgtct tatggatagt gaggtttcag
    58681 aagtgattgt ggcgactaat gctacagcgg atggtgaagc gacttccatg tatctttcac
    58741 gtttgctcaa gccagctggt atcaaggtta cgcgtctagc acgaggtctc gctgtgggag
    58801 cggacattga gtatgcggac gaagtgacac tcttacgagc gattgaaaat cggacagagt
    58861 tgtaagtgta ggcaaattta cgaactccct tcatttataa aaaatcaaag aggctgaaaa
    58921 tcgttcctat cggcctcttt ttgtatagtg tgatgagtag gatcgggttc aagttttaaa
    58981 aaaccaagca aatatgatat actaaagagc gagtattcta gtagaattag gacaaataat
    59041 atgaaacaaa cgattattct tttatatggt ggacggagtg cggaacgcga agtctctgtc
    59101 ctttcagctg agagtgtcat gcgtgcggtc aattacgacc gtttcacagt caagactttc
    59161 tttatcagtc agtcaggtga ctttatcaaa acacaggaat ttagtcatgc tccggggcaa
    59221 gaagaccgtc tcatgaccaa tgaaaccatt gattgggata agaaagttgc accaagtgct
    59281 atctacgaag aaggtgcagt ggtctttcca gtccttcacg ggccaatggg agaagatggc
    59341 tctgttcaag gattcttgga agttttgaaa atgccttacg ttggttgcaa cattttgtca
    59401 tcaagtcttg ccatggataa aatcacgact aagcgtgttc tggaatctgc tggtattgcc
    59461 caagttcctt atgtggctat cgttgaaggc gatgatgtga ctgctaaaat cgctgaagtg
    59521 gaagaaaaat tggcttatcc agtcttcact aagccgtcaa acatggggtc tagtgtcggt
    59581 atttctaagt ctgaaaacca agaagaactc cgtcaagcct taaaacttgc cttccgatat
    59641 gacagccgtg tcttggttga gcaaggagtg aatgcccgtg aaattgaggt tggcctcttg
    59701 ggtaactacg atgtcaagag cacgctacct ggagaagttg tcaaggacgt tgccttttat
    59761 gactacgatg ccaagtatat tgataacaag attactatgg atattcctgc caaaatcagt
    59821 gatgatgtgg tagctgtcat gcgtcaaaat gcagaaacag ccttccgtgc cattggtggc
    59881 cttggtctat ctcgttgcga tttcttctat acagataagg gagagatttt tctcaacgag
    59941 ctcaatacca tgccaggttt cacccagtgg tctatgtacc cactactttg ggacaatatg
    60001 gggatcagct acccagaact aatcgagcgt ttggttgacc ttgccaagga aagttttgac
    60061 aagcgcgaag cgcatttgat ataaaatgaa agagagggta gaagccagaa ccatcactgc
    60121 aaggtgacta gagttctcgg acttcagccc tttttaaagg agtagaaatg aaattaacaa
    60181 tccatgaagt tgcccaagtt gttggagcca aaaatgatat cagtatcttt gaggacaccc
    60241 agttagaaaa agctgagttt gatagtcgtt tgattggaac tggagattta tttgtgcccc
    60301 taaaaggtgt gcgtgacggt catgacttta tcgaaagagc ttttgaaaat ggtgcggcag
    60361 caaccctgtc tgagaaagag gttgcaaatc atccctacat tctagtagat gatgttttga
    60421 ctgcctttca acaactagct gcctactatc ttgaaaaaac agctgttgat gtctttgcgg
    60481 ttacgggttc aaatggcaag acaacgacta aggatatgtt ggcgcattta ctgtcaacaa
    60541 gatacaagac ctacaaaaca caaggcaatt acaataatga gattggcctt ccttacacag
    60601 ttctccacat gcctgaagga acagaaaagt tggtcttgga gatggggcag gaccacttgg
    60661 gagatattca tctcttgtct gaattggctc gtccaaaaac agccatcgtg accttggttg
    60721 gagaagctca tttggccttt ttcaaagatc gttctgagat tgctaaagga aaaatgcaaa
    60781 ttgcagacgg aatggcttca ggttccttgc ttttagcgcc ggctgaccct atcgtagagg
    60841 actatttgcc aactgataaa aaggtggttc gttttggtca aggagcagag ctggaaatta
    60901 ctgacttggt tgagcgcaaa gatagtctga ccttcaaggc caatttctta gagcaagtcc
    60961 ttgatttgcc agtaactggc aagtacaatg cgacaaatgc tatgattgca tcctatgttg
    61021 ccttgcaaga aggagtttca gaggagcaaa ttcgtttggc cttccaacat cttgaattga
    61081 cgcgtaaccg taccgagtgg aagaaagcag ccaatggagc agacatcttg tcagatgttt
    61141 acaatgccaa tccaactgct atgaagctga ttttagagac cttctctgcc attccagcca
    61201 atgaaggtgg caagaaaatt gcagtgttgg cggatatgaa ggaacttggt gtccagtctg
    61261 ttcaacttca taatcagatg attttgagcc tttcgccaga tgtgcttgat actgttattt
    61321 tctacggaga agatattgct gaattagccc aacttgctag tcaaatgttc ccaatcggac
    61381 acgtttatta cttcaagaaa acagaagacc aagaccaatt tgaagaccta gttaagcagg
    61441 tcaaagaaag ccttggggct catgaccaaa tcctgctcaa aggctctaac tctatgaatc
    61501 tagccaagtt ggtagaaagt ttagaaaatg aagacaagtg attttgtcaa gtatttgcaa
    61561 agaatgattg ccattacaga tactggatta acctttacaa aagatccgtt tgaccgtgag
    61621 cgctacgaag acttgcgaga ccttctatct gaaatgttga atcaagcatc agaccttgat
    61681 tccgaagaag tggcagaagt cttgaagcca acttctgctt atgcgactcc cttaatggac
    61741 gtccgtgctt ggattgttga ggacgaaaag atttgtctgg ttaggggaca aggagaggat
    61801 agttgggctt tgccaggtgg ctttggtgaa gtcggctatt ctccaactga aaatattctc
    61861 aaggaaattg aagaagaaac cggttttaaa gccaaagttg aaagactgct agctgttttt
    61921 gataccaatc gtttccaact acagagcaaa caatatgcaa agtttgtttt tgaatgtaag
    61981 cttctcgatg gacaattcca agaaaatcaa gaaatcgctg accttcaatt ttttgcaatt
    62041 gacccactgc cgaatttatc tgaaaaacgc attaccaagg agcaaatcga gattctttgg
    62101 caggtttatc aaggtcagag ggagcaatat cttgactaag aagatgatta tcgtatttct
    62161 aaattcattt ttcttaagta gcatggtata ataaaatgca ggaaaatttt gaatcatgag
    62221 gaagactaga tgaatttatg ggatattttc tttacgactc aggcaaccga gccgcccaaa
    62281 tttgaccttt tttggtatgt tagcctattt acgctcttag ccttaacctt ttatacagcc
    62341 catcgctatc gtgaaaagaa ggtttaccaa cgatttttcc aaatcttgca gactgttcag
    62401 ttaatccttc tttatggttg gtactgggtc aatcatatgc cactgtcaga aagcctaccc
    62461 ttttaccatt gccgtatggc tatgtttgtg gtactcttgc ttcctggtca gtccaaatat
    62521 aaacaatact ttgcattatt gggaacattt gggacattag cagcctttgt ttatccagtg
    62581 ccagatgctt acccttttcc acatatcacc attctatcct ttatctttgg tcatttagca
    62641 ctcttgggga actctctagt ttatctattg agacagtata atgcgcgatt gctggatgtg
    62701 aagggaattt ttctcatgac ctttgcccta aatgccttga tttttgtggt caatttggtg
    62761 acaggtggcg attacggatt tttgacaaaa ccgccattgg ttggggatca cggtctagta
    62821 gctaattatt tacttgtttc aattgtgctg gtagctacta tcagtttgac taagaaaatc
    62881 ttagaattct ttttagctca agaagcagaa aaaatgattg caaaggaagc ttaacacaga
    62941 gctttctttt ttgctcttag agagttttta caagcagctt ataaaataag aatttctgaa
    63001 tagacaaact caaaaaatgg ctgggaaatt taggaaaaaa gcaagcacga ttaaattttt
    63061 tgtgttataa tattttgtga atagctatgc ctatgtttag ctatggaata atacgaagtg
    63121 cgaaacttgg aagatagaga ggaagcgatg taatggctag agaaggcttt tttacaggtc
    63181 tagatattgg aacaagctct gtcaaggtgc ttgtggccga gcagagaaat ggtgaattaa
    63241 atgtaattgg cgtgagtaat gccaaaagta aaggtgtaaa ggatggaatt attgttgata
    63301 ttgatgcagc agcaactgct atcaagtcag ccatttccca agcggaagaa aaggcaggca
    63361 tttcgattaa atcagtaaat gtcggcttgc ctggtaatct tttgcaggta gaaccaactc
    63421 aggggatgat tccagtaaca tctgatacta aggaaattac ggatcaagat gttgaaaatg
    63481 ttgtcaaatc agctttgaca aagagtatga cacctgaccg tgaagtcatt acctttattc
    63541 ctgaagaatt tattgtggat ggtttccaag ggattcgtga cccacgtggc atgatggggg
    63601 ttcgccttga aatgcgtggt ttgctttata caggacctcg tactatcttg cacaatttgc
    63661 gtaagacggt tgagcgtgca ggtgttcagg ttgaaaatat tatcatttca ccactagcaa
    63721 tggttcagtc tgttttgaat gaaggggaac gtgaatttgg tgctacagtg attgatatgg
    63781 gggcaggtca aacgactgtc gctacaatcc gtaatcaaga actccagttc acacatattc
    63841 tccaagaagg tggagattat gtaactaaag atatctccaa ggttttgaaa acctctcgca
    63901 aattagcgga aggcttgaaa ctgaattacg gggaagccta tccgcctctt gcaagcaaag
    63961 aaaccttcca agtagaggtt attggagaag tggaagcagt cgaagtgacg gaagcctact
    64021 tgtcagaaat tatttctgca cgaatcaagc acatccttga acaaatcaag caagaattag
    64081 atagaaggcg tctattggac ctccctggtg gtattgtctt aatcggtggg aatgccattt
    64141 taccaggtat ggttgagctt gctcaggaag tctttggcgt ccgtgtcaag ctttatgttc
    64201 caaatcaagt tggtatccgt aatccagcct ttgcgcatgt gattagttta tcagaatttg
    64261 cgggtcaatt aacagaagtt aatcttttgg ctcagggagc gataaaaggt gagaatgact
    64321 taagtcatca gccaattagt tttggtggga tgctgcaaaa aacagctcag tttgtacaat
    64381 caacgcctgt tcaaccagct cctgctccag aagtagagtc ggtggcgcct acagaaccaa
    64441 tggcggattt ccaacaagct tcacaaaata aaccgaaatt agcagatcgt ttccgtggct
    64501 tgatcggaag catgtttgac gaataaagag gaaaaataaa ttatgacatt ttcatttgat
    64561 acagctgctg ctcaaggggc agtgattaaa gtaattggtg tcggtggagg tggtggcaat
    64621 gccatcaacc gtatggtcga cgaaggtgtt acaggcgtag aatttatcgc agcaaacaca
    64681 gatgtacaag cattgagtag tacaaaagct gagactgtta ttcagttggg acctaaattg
    64741 actcgtggtt tgggtgcagg aggtcaacct gaggttggtc gtaaagccgc tgaagaaagc
    64801 gaagaaacac tgacggaagc tattagtggt gccgatatgg tcttcatcac tgctggtatg
    64861 ggaggaggct ctggaactgg agctgctcct gttattgctc gtatcgccaa agatttaggt
    64921 gcgcttacag ttggtgttgt aacacgtccc tttggttttg aaggaagtaa gcgtggacaa
    64981 tttgctgtag aaggaatcaa tcaacttcgt gagcatgtag acactctatt gattatctca
    65041 aacaacaatt tgcttgaaat tgttgataag aaaacaccgc ttttggaggc tcttagcgaa
    65101 gcggataacg ttcttcgtca aggtgttcaa gggattaccg atttgattac caatccagga
    65161 ttgattaacc ttgactttgc cgatgtgaaa acggtaatgg caaacaaagg gaatgctctt
    65221 atgggtattg gtatcggtag tggagaagaa cgtgtggtag aagcggcacg taaggcaatc
    65281 tattcaccac ttcttgaaac aactattgac ggtgctgagg atgttatcgt caacgttact
    65341 ggtggtcttg acttaacctt gattgaggca gaagaggctt cacaaattgt gaaccaggca
    65401 gcaggtcaag gagtgaacat ctggctcggt acttcaattg atgaaagtat gcgtgatgaa
    65461 attcgtgtaa cagttgttgc aacgggtgtt cgtcaagacc gcgtagaaaa ggttgtggct
    65521 ccacaagcta gatctgctac taactaccgt gagacagtga aaccagctca ttcacatggc
    65581 tttgatcgtc attttgatat ggcagaaaca gttgaattgc caaaacaaaa tccacgtcgt
    65641 ttggaaccaa ctcaggcatc tgcttttggt gattgggatc ttcgccgtga atcgattgtt
    65701 cgtacaacag attcagtcgt ttctccagtc gagcgctttg aagccccaat ttcacaagat
    65761 gaagatgaat tggatacacc tccatttttc aaaaatcgtt aagtaaatga atgtaaaaga
    65821 aaatacagaa cttgtttttc gagaagttgc agaggctagt ctgagtgctc atcgagagag
    65881 tggttcggtc tctgtcattg cagttaccaa gtatgtagat gtaccgacag cggaagcctt
    65941 gcttccgcta ggtgttcatc atatcggtga aaatcgtgta gataagtttc tggaaaaata
    66001 tgaagcttta aaagatcgag atgtgacttg gcatttgatt ggtaccttgc aaagacgtaa
    66061 ggtgaaagat gtcattcaat acgttgatta tttccatgca ttggactcag taaagctagc
    66121 aggggaaatt caaaaaagaa gtgaccgagt catcaagtgt ttccttcaag taaatatttc
    66181 taaagaagaa agcaaacacg gtttttcgag agaggaactg ctggaaatct tgccagagtt
    66241 agccagacta gataagattg aatatgttgg tttaatgacg atggcacctt ttgaggctag
    66301 cagtgagcag ttgaaagaga ttttcaaggc gacccaagat ttacaaagag aaattcaaga
    66361 gaaacaaatt ccaaatatgc ctatgaccga gttaagtatg ggaatgagtc gtgattataa
    66421 agaagcgatt caattcggtt ccacttttgt tcgtataggt acatcatttt ttaagtagga
    66481 gagaaccatg tctttaaaag atagattcga tagatttata gattatttta cggaggatga
    66541 ggattcaagt ctcccttatg aaaaaagaga tgagcctgtg tttactccag taaattcttc
    66601 acaggaaccg gctctcccaa tgaatcaacc ttcacagtcg gctggtacaa aagagaacaa
    66661 tatcaccaga cttcatgcaa gacaacagga attggcaaat cagagtcagc gtgcaacgga
    66721 taaggtcatt atagatgttc gttatcctag aaaatatgag gatgcaacag aaattgttga
    66781 tttattggca ggaaacgaaa gtatcttgat tgattttcag tatatgacag aggtgcaggc
    66841 tcgtcgttgt ttggactatt tggatggagc ttgtcatgtt ttagctggaa atttgaaaaa
    66901 ggtagcttct accatgtatt tgttgacacc agtgaatgtt attgtaaatg ttgaagatat
    66961 ccgtttacca gatgaagatc aacagggtga gttcggtttt gatatgaagc gaaatagagt
    67021 acgataatga tttttttaat tcgtatgatt tataatgcag tggatattta ctccctgatt
    67081 ttggtagcct tcgctgtcat gtcttggttt ccaggtgcct acgaatccag tttaggtcgt
    67141 tggattgtag cgttggtgaa accagtgctt gctcccttgc aacgcctgcc tttacagata
    67201 gcgggtcttg atttatctgt ttgggtcgcg attgttttgg ttcgattttt aggagaaaac
    67261 ctagtgcgtt ttctggcgat gataggatga ataaagggat ttatcagcat ttctccatag
    67321 aagatcgtcc atttcttgac aagggaatgg aatggataaa gaaggtagaa gatagctatg
    67381 ctcctttttt aactcctttt atcaatcctc atcaggagaa gctattaaag attttggcca
    67441 aaacctatgg tcttgcttgt agcagtagtg gggaattcgt ctcgagtgag tatgttcgag
    67501 ttttattata cccagattat ttccaaccag agttttcaga ttttgaaata tctctccagg
    67561 aaattgtgta ttccaataaa tttgaacatt taacgcatgc taagatttta gggacagtca
    67621 tcaatcaatt agggattgaa cggaaacttt ttggagatat cctagtagat gaagaacggg
    67681 cgcagattat gattaatcag cagtttcttc ttctctttca agatggacta aagaaaattg
    67741 gtcgtatacc tgtttcgctg gaggaacgtc ctttcaccga gaaaatagat aagctagaac
    67801 agtatcgaga actggattta tctgtgtcta gttttcgatt agatgttctt tgttcaagtt
    67861 ggagacttga ttagtgtgag aaaatttggt cgcttgagat tacttcaaga taagggacaa
    67921 acgaaaaaag agaagaaaaa aataaccgtc cagttattat taagtaagtg aggaatagaa
    67981 tgccaattac atcattagaa ataaaggaca agacttttgg aactcgattc agaggttttg
    68041 atccagaaga agtcgatgaa tttttagata ttgtggttcg tgattacgaa gatcttgtgc
    68101 gtgcgaatca tgataaaaat ttgcgtatta agagtttaga agagcgtttg tcttactttg
    68161 atgaaataaa agattcattg agccagtctg tattgattgc tcaggataca gctgagagag
    68221 tgaaacaggc ggcgcatgaa cgttcaaaca atatcattca tcaagcagag caagatgcgc
    68281 aacgcttgtt ggaagaagct aaatataagg caaacgagat tcttcgtcaa gcaactgata
    68341 atgctaagaa agtcgctgtt gaaacagaag aattgaagaa caagagccgt gtcttccacc
    68401 aacgtctcaa atctacaatt gagagtcagt tggctattgt tgaatcttca gattgggaag
    68461 atattctccg tccaacagct acttatcttc aaaccagtga tgaagccttt aaagaagtgg
    68521 ttagcgaagt acttggagaa ccgattccag ctccaattga agaagaacca attgatatga
    68581 cacgtcagtt ctctcaagca gaaatggaag aattacaagc tcgtattgag gtagccgata
    68641 aagaattgtc tgaatttgaa gctcagatta aacaggaagt ggaaactcca actcctgtag
    68701 tgagtcctca agttgaagaa gagcctctgc tcatccagtt ggcccaatgt atgaagaacc
    68761 agaagtagct ccagtgcatc cgacaggtcc aacaccagct acagaaactg ttgattcagc
    68821 accgggattt gaagcaccgc aagaatctgt tacaatttta taagaaatat tctgagaaca
    68881 atatcttatc cttatattcc cagcgagcag gagatggtgt gagtcctgca ttccctatcg
    68941 ataagattat cctctcaaac tatcaagtct gaatctagta agatttgacg ttccccacgt
    69001 tacgggataa gagggagaaa gactaaaact ttttccgaat aaaggtggta ccacgatttt
    69061 cgtccttttt ggaagtcgtg gtttttaatt tgttattatt tataaaggag ataccatgaa
    69121 actcaaagac acccttaatc ttgggaaaac tgaattccca atgcgtgcag gccttcctac
    69181 caaagagcca gtttggcaaa aggaatggga agatgcaaaa ctttatcaac gtcgtcaaga
    69241 attgaaccaa ggaaaacctc atttcacctt gcatgatggc cctccatacg ctaacggaaa
    69301 tatccacgtt ggacatgcta tgaacaagat ttcaaaagat atcattgttc gttctaagtc
    69361 tatgtcagga ttttacgcac catttattcc tggttgggat actcatggtc tgccaatcga
    69421 gcaagtcttg tcaaaacaag gtgtcaaacg taaagaaatg gacttggttg agtacttgaa
    69481 actttgccgt gagtacgctc tttctcaagt agataaacaa cgtgaagatt ttaaacgttt
    69541 gggtgtttct ggtgactggg aaaatccata tgtgaccttg actcctgact atgaagcagc
    69601 tcaaattcgt gtatttggtg agatggctaa taagggttat atctaccgtg gtgctaagcc
    69661 agtttactgg tcatggtcat ctgagtcagc ccttgctgaa gcagagattg aataccatga
    69721 cttggtttca acttcccttt actatgccaa caaggtaaaa gatggcaaag gagttctaga
    69781 tacagatact tatatcgttg tctggacaac gactccattt actatcacag cctctcgtgg
    69841 tttgacggtt ggtgcagata ttgattacgt tttggttcaa cctgctggtg aagctcgtaa
    69901 gtttgtcgtt gctgctgaat tattgactag cttgtctgag aaatttggct gggctgatgt
    69961 tcaagttttg gaaacttacc gtggccaaga actcaaccac atcgtaacag aacacccatg
    70021 ggatacagct gtagaagagt tggtaattct tggtgaccac gttacgactg actctggtac
    70081 aggtattgtc catacagccc ctggttttgg tgaggacgat tacaatgttg gtattgctaa
    70141 taatcttgaa gtcgcagtga ctgttgatga acgtggtatc atgatgaaga atgctggtcc
    70201 tgaatttgaa ggtcaattct atgaaaaggt agttccaact gttattgaaa aacttggtaa
    70261 cctccttctt gcccaagaag aaatctctca ctcatatcca tttgactggc gtactaagaa
    70321 accaatcatc tggcgtgcag ttccacaatg gtttgcctca gtttctaaat tccgtcaaga
    70381 aatcttggac gaaattgaaa aagtgaaatt ccactcagaa tggggtaaag tccgtcttta
    70441 caatatgatc cgtgaccgtg gtgactgggt tatctctcgt caacgtgctt ggggtgttcc
    70501 acttcctatc ttctacgctg aagatggtac agctatcatg gtagctgaaa ctattgaaca
    70561 cgtagctcaa ctttttgaag aacatggttc aagcatttgg tgggaacgtg atgccaaaga
    70621 cctcttgcca gaaggattta ctcatccagg ttcaccaaac ggcgagttca aaaaagaaac
    70681 tgatatcatg gacgtttggt ttgactcagg ttcatcatgg aatggagtgg tggtaaaccg
    70741 tcctgaattg acttacccag ccgaccttta cctagaaggt tctgaccaat accgtggttg
    70801 gtttaactca tcacttatca catctgttgc caaccatggc gtagcacctt acaaacaaat
    70861 cttgtcacaa ggttttgccc ttgatggtaa aggtgagaag atgtctaaat ctcttggaaa
    70921 taccattgct ccaagcgatg ttgaaaaaca attcggtgct gaaatcttgc gtctctgggt
    70981 aacaagtgtt gactcaagca atgacgtgcg tatctctatg gatatcttga gccaagtttc
    71041 tgaaacttac cgtaagattc gtaacactct tcgtttcttg attgccaata catctgactt
    71101 taacccagct caagatacag tcgcttacga tgagcttcgt tcagttgata agtacatgac
    71161 gattcgcttt aaccagcttg tcaagaccat tcgtgatgct tacgcaaact ttgaattctt
    71221 gacaatctac aaggccttgg tgaactttat caacgttgac ttgtcagcct tctaccttga
    71281 ttttgccaaa gatgttgttt acattgaagg tgccaaatca ctggaacgcc gtcaaatgca
    71341 gactgtcttc tatgacattc ttgtcaaaat caccaaactc ttgactccaa tccttcctca
    71401 cactgcggaa gaaatctggt catatcttga gtttgaagcc gaagacttcg tccaattgtc
    71461 agaattacca gaagttcaaa cttttgctaa ccaagaagaa atcttggata catgggcagc
    71521 cttcatggac ttccgtggac aagcacaaaa agccttggaa gaagctcgta atgcaaaagt
    71581 tatcggtaaa tcacttgaag cacacttgac agtttatcca aatgaagttg tgaaaactct
    71641 actcgaagca gtaaacagca atgtagctca acttttgatc gtgtctgagt tgaccatcgc
    71701 agaagaacca gctccggaag ctgcccttag cttcgaagat gtagtcttca cagttgaacg
    71761 cgctgcaggt gaagtatgtg accgttgccg tcgtattgac ccaacaacag cagaacgtag
    71821 ctaccacgca gtcatctgtg accactgtgc aagtatcgta gaagaaaact ttgcagatgc
    71881 agtcgcagaa ggatttgaag agaaataaga ttgaaaagtc taggtaaaac tcaatttgag
    71941 aagaaaagac aactaatttt atagtctatt aaacgcattg tatcacgttt ttgaacacct
    72001 gatatgatgc gttttttatt tattttaaaa atttgcgagg tatgactttt tatactcaac
    72061 aagaatcaaa gagaaactta gcaagctaac agtagtaata taaaatagga atttgatatt
    72121 agggataaga ttggtaaata gtgtaatatt tttacaacaa taaatttata tagttatttc
    72181 tggtttctga aaagtattat attatatttt atttcatatt atacaaattt ttattttata
    72241 atatcagaaa atactttttt taaaaagcaa atatgataca attttatttg aaaaaaaata
    72301 aaaaaggaga ttttattatg aaatcaagtg gtatcgtcgg tcttgtggga ggaattttac
    72361 ttcttatttg tccttttgtc ttgttgggaa cagcggtaaa tacagctgct acaactctta
    72421 atggaggagc tactgcaggg gctttttcag gtgttgcctt actcttgaat gccttgaaga
    72481 ttgcaaatct tgttcttggt atcattgcta ttgtttacta taaaggagat aagcatgtag
    72541 gtgcagctcc gtctgtacta atgattgttt ctggtgaagt tagtctcatt ccattcttag
    72601 gatgggttgg ggggattctt gctattatcg gaggatctct attccttgca acattgaaga
    72661 aattcaaatc agaagaataa aaggtatttt agcatgaaaa gaacaaaaaa gtttatcggt
    72721 ataggagtag ctctattatc tctttctctt ctagttgcat gtggaacata aagttcaaag
    72781 aatacttcaa caagtaatga tgagaagaca gtagcaacat ccaatagttc aaaagaaaca
    72841 atcactttcg atacaccggt tgtaacagac gatgcgattg aatcaatacg cacttatgca
    72901 gattatatag atctttataa aaatattttt gatgattatt ttactaaagc tgaggaaggt
    72961 ttcaaaggca caactatgga aaataatgac tcgtttacta aactaaaaga gtcaactcaa
    73021 aaattattcg atgcgcagaa aaaaaggtta aataatgaag atagaataga aacaaccaaa
    73081 aacaatgtga ttgccaaaca ttgtcaaaca gtcctttcct ttttggtttt gactagcttt
    73141 tttgtgaaaa attgtgtaaa atagaataga taaacgaggg gaaacctcgg aaaatttaaa
    73201 ggagaatcca tctaatggta aaattggttt ttgctcgcca cggtgagtct gaatggaaca
    73261 aagctaacct tttcactggt tgggctgatg ttgatttgtc tgaaaaaggt acacaacaag
    73321 cgattgacgc tggtaaattg atcaaagaag ctggtatcga atttgaccaa gcttacactt
    73381 cagtattgaa acgtgctatc aaaacaacta acttggctct tgaagcttct gaccaattgt
    73441 gggttccagt tgaaaaatca tggcgcttga acgaacgtca ctacggtggt ttgactggta
    73501 aaaacaaagc tgaagctgct gaacaatttg gtgatgagca agttcacatc tggcgtcgtt
    73561 catacgatgt attgcctcca aatatggacc gtgatgatga gcactcagct cacacagacc
    73621 gtcgttatgc ttcacttgac gactcagtca ttccagatgc tgaaaacttg aaagtgactt
    73681 tggaacgtgc tcttccattc tgggaagata aaatcgctcc agctcttaaa gatggtaaaa
    73741 acgtattcgt aggagctcac ggtaactcaa tccgtgccct tgtaaaacac atcaaaggtt
    73801 tgtcagatga tgagatcatg gacgtggaaa tccctaactt cccaccattg gtattcgaat
    73861 tcgacgaaaa attgaacgtt gtttctgaat actaccttgg aaaataaaaa attgtaagcc
    73921 taggattgat ttctaggctt tttatgttag tatggaagta tgataaggaa taaaaaacaa
    73981 gattatgtac tggcctacaa gcaaccagct tcaaccactt acatgggttg ggaagaagaa
    74041 gctttaccga taggcaatgg ttctttagga gcaaaagtat ttggccttat aggggctgaa
    74101 cggattcaat ttaatgaaaa aagtctctgg tctggaggtc cacttcctga tagttcagat
    74161 tatcagggtg gaaatcttca ggatcagtat gtttttttag ctgagattcg gcaggctttg
    74221 gagaagagag attacaatct ggctaaggaa ctggctgagc agcacctaat tgggccaaaa
    74281 acgagtcaat atgggaccta tctgtctttt ggggatattc acattgagtt cagccagcaa
    74341 ggtacgactt tgtctcaggt gacggactat cagagacagc tgaatattag taaggcactt
    74401 gcgacgactt cttatgtcta taagggaacg cgatttgaac gtaaagcttt tgcgagtttt
    74461 ccagatgatc tcttgattca atgttttact aaggaagggt tggaaactct agattttact
    74521 atagaactat ccttgacctg tgatttggct tctgatggaa agtatgagca ggaaaaatct
    74581 gattacaagg agtgtaagtt ggatattact gattctcata tcttgatgaa gggaagagtt
    74641 aaggataatg atctgcggtt tgctagttat ctagcttggg aaacggatgg agatattaga
    74701 gtttggtcag atagggttca gatatcagga gccagttatg ccaatctctt cttggccgct
    74761 aagacggatt ttgcccaaaa tcctgctagc aattatcgca agaaactaga tttagagcaa
    74821 caggtgatag acttggtgga cacagctaaa gaaaagggct atacccaatt gaaatcaagg
    74881 catatcgagg actaccaagc cttattccag cgtgttcaat tggatttgga agctgatgtt
    74941 gacgcatcca ctacagatga tttgttaaaa aattataagc cacaagaagg gcaggctttg
    75001 gaggagctgt tcttccagta tggacggtat ttattgatta gttcgtccag agactgccca
    75061 gatgctctac cagctaacct acagggagtc tggaatgcgg tcgacaatcc tccttggaat
    75121 tcggactatc acttaaatgt caatctgcag atgaattatt ggccagccta tgttaccaat
    75181 ctcctagaga cggtctttcc agtcatcaac tatgtagatg atttgcgtgt ctatggtcgt
    75241 ctagcggctg taaagtatgc aggaatcgtc tctcaaaaag gtgaggaaaa tggttggttg
    75301 gttcatactc aagcgactcc ctttggttgg acggcacctg gttgggatta ctattggggt
    75361 tggtcaccag ctgccaatgc gtggatgatg caaaccgttt atgaagccta ttcattttat
    75421 agggaccaag actatctcag ggagaaaatt tatcccatgt tgagggaaac ggttcgtttt
    75481 tggaatgcct ttttacataa ggatcagcag gcgcagcgtt gggtctcttc tccgtcttat
    75541 tccccagaac atgggccgat ttcgattggc aatacctatg accaatctct gatttggcag
    75601 ttatttcatg attttattca ggctgctcag gaattgggac tggatgagga cttgttgact
    75661 gaggttaagg agaagtctga tttactaaat cctttgcaaa tcactcaatc tggtcgaatc
    75721 agggagtggt atgaggagga agagcagtat tttcaaaatg agaaagtgga ggcccagcat
    75781 cggcacgctt cccatctagt gggactctat tctggcaatc tctttagcta caagggacaa
    75841 gagtatattg aagcggcgcg tgctatcctc aatgatcgtg gagatggcgg cacaggctgg
    75901 tccaaggcta ataagatcaa tctctgggcg cgtttgggag atggcaatcg agcccataaa
    75961 ttattggcag agcagttaaa gacatccacc ttgccaaatc tttggtgtag ccatcctcct
    76021 tttcagatag atggtaattt tggtgctact agtggcatgg cagaaatgtt actccagtct
    76081 catgcagctt atctggtacc tctagctgcc ctacctgatg cttggtcaac aggttctgtt
    76141 tcaggcttaa tggcacgtgg acattttgaa gtgagcatga gctgggaaga taaaaaactc
    76201 ttacagttga ccattttatc aaggagtgga ggagatttgc gagtttctta tccagatatt
    76261 gagaagagtg tgattaaaat gaatcaagaa aaaataaaag cgaaatgcat ggggaaagat
    76321 tgtatttcgg tggcaacagc agaaggtgat cttgttcaat tttattttta agaagatgtt
    76381 ataaggcagt aatttgaaac ttccttttaa taaggatttg agaatatagg cagtttccaa
    76441 ctagttgaaa aagcgttata atgataatag gaagtaatac tcaatgaaaa tcaaagagca
    76501 caaactagga agctagccgc aggttgctca aaacagtgtt ttgaggttgt agatggaagc
    76561 tgacgtggtt tgaagagaga ttttcgagga gtataatttg tttgatagag ggtgggtctg
    76621 atggcttata ttgagatgaa acactgttac aagcgttatc aggttgggga cacggagatt
    76681 gtggccaatc gtgatgtgaa ttttgagatt gaaaaggggg agctggttat tatccttggt
    76741 gcttcaggtg caggcaagtc aacagttctt aaccttcttg ggggaatgga taccaatgat
    76801 gaaggggaaa tctggattga tggtgttaat attgcggatt atagttccca ccagcgtacc
    76861 aattaccgta gaaatgatgt ggggtttgtt tttcagtttt ataatctagt ttctaatctg
    76921 acagctaagg aaaatgtgga actggcttct gaaattgtga cagatgcctt gaatcctgat
    76981 caggtcttga cagatgtagg tctggctcat cgtctcaata actttccagc ccagctttct
    77041 ggaggggagc aacagcgagt ctccattgca cgcgcggtag ccaaaaatcc taaaattctc
    77101 ctttgtgatg aaccgactgg agccttggat tatcagacgg gcaagcaggt tttgaaaatt
    77161 ctccaagaca tgtctcgtca aaagggagcg acggtgatca tcgtgactca taatggagct
    77221 ttggcgccca ttgctgatcg cgtgattcaa atgcacgatg ccagtgtcaa ggatgtggtg
    77281 ctcaaccagc atcctcagga tattgacagt ttggagtact agcatgatca agcgaaaaac
    77341 ttattggaag gacttaattc agtccttcac aggctccaag gggcgttttt tatccatctt
    77401 gatcctgatg atgttgggat ctctagcctt agtaggcctc aaagtaacca gtcccaacat
    77461 ggaggcgaca gctaatgctt atttaacaac tgctcaaacc ttggatttgg cagtcatgtc
    77521 taactatggc ttggatcaag cagaccaaga agaactaaaa cagacggagg gcgcagaggt
    77581 cgagtttggc tatttgacag atgtgactat ggataatggg caggatgcca ttcggctgta
    77641 ctccaaacca gagcgaattt caacctttca gctaagaaag ggacgacttc ctcagtcaga
    77701 caaggaaatc gctttggcca ctcatttgca aggccaatac agcgtgggac aggagattag
    77761 ttttaaagaa aaagaagagg gtcattcctc tttaaaagac catacttata ccattactgg
    77821 ttttgtggat tcggctgaaa tcctctccca gcgagatatg ggctacgcag gaagtggaag
    77881 tgggactctg acagcctatg gggtgatttt acctagtcag tttgatcaga aagtctacaa
    77941 tatagctcgt ttgaaatatc aagatttagc aggtttaaat gccttttcat cagcttatga
    78001 agaaaaatcc aagcaacatc aggaagacct tgaacaaact ttatcagata atggcaaggt
    78061 acgtctgcaa cttttgaaaa aagaaggaca agagtctcta gacaaggggc aagagaccct
    78121 tgacaaggct cagactaatt tgcaggaagg caagcgtcgt ttagcagctg ctcaagctcg
    78181 tatacaggct caagaaagtc aactagcctt gtttcctcaa gttcagagag agcaggctag
    78241 tgctcaactt acccaagcca agcaggaatt gggcaaggaa gaggataaac taaagcaagc
    78301 tgaacaaaat ctagcccaag aaaaggaaaa attagaaaaa catcagcaag tcttggacga
    78361 tttggcggag ccaaggtatc aggtctataa tcgtcagacc atgccaggtg gtcagggcta
    78421 tcttatgtat agcaatgctt catccagtat tcgagcagtg ggcaatatct ttcctgtggt
    78481 actttatgcc gtagcatcca tggtgacctt tacgaccatg actcgctttg tagacgaaga
    78541 gcgaactcat gcagggattt ttaaggcctt gggttaccgt agtaaggata ttatcaccaa
    78601 gtttctcctt tatggactag tagctgggac tgtcggaacg gctctaggta gtatacttgg
    78661 tcattatttg ctagccagtg taatttcaag tgtcattaca aaaggcatgg tggtgggaga
    78721 aacccagatt cagttctatt ggacctatag cttactagct cttgtcttga gctggttggc
    78781 gagtgtgtta ccagcctatc tggtggcttg gagggaactt catgccgaag cagcccagct
    78841 tctacttcct aaacctcctg tcaaaggagc taaaatctta ttggagcgta tcggttttat
    78901 ctggcgtcgt ctcagtttta ctcataaggt aacagcccgc aacatctttc gttataagca
    78961 gagaatgttg atgacaatct ttggtgtggc aggttctgta gctctgctct ttgcaggttt
    79021 gggaatccaa tcttctgtag caggagttcc gtctaaacag tttcaacaaa tccaacagta
    79081 tcagatgctt gtctctgaaa atcctagtgc gaccaatcag gacaaggtag agctagcaga
    79141 agtgttgaaa gggcaggaga tactagccta ccagaaaatc tattctaaaa cgctagacaa
    79201 ggatttcaaa ggcaaggctg gtcttcaaaa cattactctt atgatgatag agaaggaaga
    79261 tttgactccc tttatccatc ttcaacatca tcagcaggag ctgacattaa aagatggcat
    79321 cgttattaca gctaaactcg cccagctggc aggtgtcaag gttgggcaga ctttagaaat
    79381 tgaaggtaag gaactaaagg tcgctgctat tactgagaac tacgttggtc actttattta
    79441 tatgagtcag gctagctatg agcaacttta cggacagcta ccccaagcca acacttatct
    79501 ggtctcatta agggatacca gtgcaactag tatcgaaagt caggcgggct tgcttatgaa
    79561 tcaatctgcg gtgtccagcg ttgtccaaaa tgcttcagcc attcgactct atcgctagct
    79621 cactcaatca gaccatgacc atcttggtca tcgtatcagt tctattagct attgtcatcc
    79681 tttacaatct gaccaatatc aacgtagctg agagaatccg tgaactctcc actatcaagg
    79741 ttctcggttt tcataataat gaagtcaccc tctacattta ccgtgagacg attgtgctgt
    79801 cccttgtggg aatcgtactt ggtctggtag ctggtttcta tttacaccaa tttttgattc
    79861 aaatgatttc gcctgcgact attctctttt atccgcaggt aggctgggaa gtctatgtaa
    79921 tcccagtggc aacagtaagc atcattttga ccttgcttgg tttcttcgtc aattattatc
    79981 tgagaaaggt tgatatgtta gaagccctga aatctgtaga gtaaggtagt tatttttagc
    80041 tgattgaact tctatttact aatattcaaa aatcctctgt cacaaagagc agggagctct
    80101 ttgtgacaga ggattttttc tatagggctt tagcagctgc aattgcggct tcgaagtttg
    80161 gctcagaatt gatattatcc acgtattcaa cgtagcgaat cgtattgtca gtatcgagga
    80221 caaagactgc gcgtgctaat aggtgccatt cgttgatcaa gagggcataa tcgcgcccga
    80281 aagaatggtc aaagtagtct gaaagcataa tggcattgtc aaggccttca gcaccgcacc
    80341 aacgtttttg agcaaaaggt aggtccattg aaacagtcaa tacgaccgtg ttgtccagtc
    80401 cagccaattc ttcattaaaa cgacgtgttt gagttgagca gatgcctgta tcgatagaag
    80461 gaacgacact caagactttt ttcttgccat caaaatcagc cagagatttt ttagaaagat
    80521 ctgttgtagt aagagaaaaa tcaagcgcct tgtcgccgac ttgtagttgt ttacctgtaa
    80581 agctcacagg atttccgaga aaagttacca taggatactc caatcttttt tcttccattg
    80641 tatctgaaac agtcagaatt ttccaatgat ttgaccggaa atgtgggcat agaaaaaacg
    80701 ccagctcaca tgagaatgac gtttttcaga ggcttatttt gccaatcctt cagcaatctt
    80761 gtcaaggttg tatttcatca tgctgtagta gctgtcgcct tctttacctt gttctgcgat
    80821 agagtcagta aagatttgtg cgtagattgg gatgtttgtg tcttgagaaa cagttttcat
    80881 tggacggtca tccacacttg attctacaaa gagtgatgga acttttgttt ggcgaagttt
    80941 ttcaaccaag gtcttgattt gttcaggagt tccttcttct tcagtattga tttcccagat
    81001 gtaagcactt gggacaccat aggctttaga gaagtatttg aatgctcctt cgctggttac
    81061 aatgagtttc ttttcagcag ggatcttatt aaatttatcc ttactttctt tatcaagttt
    81121 gtctaactta tcagtatatt ctttgagatt tttttcatag aattctttat tgttagggtc
    81181 tttggcgctc aattgtttgg cgatattttt agcaaaaata ataccgtttt caaggttaag
    81241 ccaagcgtgt gggtcttctt ttcctttttc attttgacct tcaaggtaga taacatcaac
    81301 gccgtcgctg actgcgaagt agtctttgtt ttcagttttc ttggcatttt ctaccaattt
    81361 tgtaaaccaa gcattgccac ctgtttcaag gttgataccg ttatagaaaa tcaaatcagc
    81421 ctcagaagtt ttcttaacgt cttcaggaag tggttcgtat tcgtgtgggt cttgcccaat
    81481 cggaacgata ctatgaaggt caattttgtc accagcaata tttttagtaa tatcagcgat
    81541 gattgagttt gtagcaacaa cttttagttt ttgaccagaa gttgtatctt tttttccgct
    81601 agcacatgct acaagaatga ttgcagaaag aaagagaacg agtaatgtac ctaatttttt
    81661 cattagatcc tccaaattat tagggctttg ccccttattt taacaaatgt ttatttttca
    81721 gtttcaaata tcgttgtttg ggagcgataa agaagctaat gagaaagaaa ctagcagctg
    81781 taagcacgat actagaacct gccgcaacat taaaactata gccaataaag agtcccaaaa
    81841 ctgaagcagt agctccgaag gttgaggaaa ggaaaatcat gcttttcaga ctattagcat
    81901 acagataagc agttgcagct ggggtaatca gcatggctac aatcaggata gttccgacac
    81961 tttgcatggc tgtcacagac acgagagtca ggagtaccat gagaaggtag tgatagaaat
    82021 tgacaggcat tcccatggct ttagccaaga gttcatcaaa ggaagttatc aagagttgct
    82081 tgaagaaaat ccagattaac aagaggatgg ctgcccccac acccatagta ataaacatat
    82141 ccgtatcttg gacggccagg atattaccaa aaaggatatg gaaaaggtca gttgaacttt
    82201 tagcgacacc aatcaagatg ataccgaggg ctaagaaaga agaaaaggta atgccgatgg
    82261 cggtatcgct tttgataatc gagtttcctt tgatgtaggt aatgatgatg gcagctagca
    82321 atccaaagac aatggctccg ataaagaagt caaggcccaa gatgaaggag agggctacac
    82381 ctggtaagac agcatgtgaa atggcatctc ccatgagtga catcccgcgt agaataatga
    82441 aacatcccac agctccagct acaatcccga cgacaatagc tgttatcaag gcattttgta
    82501 ggaaatggaa tttttgcaat ccatcgataa attctgcaat cataggtcac ctccattgaa
    82561 aaagagttga ttaccgtaag cttcttttag attggtttcg gtaaaagttt cttttgttgg
    82621 accaaaggca atcacttctc gattgacaag taagacttga tcgaagtagt ggggaatctt
    82681 gctgaggtcg tggtgaacga tgagaaccgt cttcccagct tttttcaaat ctctcagcgt
    82741 attcatgatg atttcctcac tgacagagtc aatcccagca aagggttcat ccaagaggat
    82801 atagtcggct tcctgcacca aacatctggc aatcaaaacc cgctggaatt gacctccaga
    82861 cagttgacta atttgacgtt cagcgtagtc agctaggccg acgatttcaa gggcctcttg
    82921 cactttcttc caatgtttag cctttaaact tcgaaagaga ggaatagagg gaaatagtcc
    82981 taacgagacg cattccttga ccttgatggg aaagttgtag tcgatattga ttttttgttc
    83041 gacataggca attcggtgta aggatttttt aacttccttg tcatcgagaa atgcctgacc
    83101 ttgatgtggg ataattccca gcataccttt taatagtgtt gatttcccag cgccgtttgg
    83161 accaatgatg ccggtaattg ttggtccatg gagcactagt gaaatatcct taagtgccaa
    83221 cgtttctttg taggagacac tgaggttttc gatacgtatc ataaacttgt attcctcctg
    83281 tctcttaata tacattaaaa aaaaaattaa gtcaagttaa tttttgaaaa aattaaaata
    83341 ataactgaaa aataga
//
LOCUS       DAVAZV010000002        80397 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVAZV010000002 DAVAZV010000000
VERSION     DAVAZV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 80397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80397
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.002"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            134..1153
                     /locus_tag="VQT46_000077"
     CDS             134..1153
                     /locus_tag="VQT46_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HET2370189.1"
                     /translation="MLYVGIDIAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     LRQLNQDCLIALENTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTNKK
                     DAHGIALKLLSDPNREQFQHDNRQVELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVEKHSEYTYQLLTCYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGNRLEAVILAEIRNIHAF
                     DNPAQLQAFAGLDSSIYQSGQIDLAGRMIKRGSPHLRWALIQAAKACPRFSPAFKAYL
                     KTKLE"
     gene            complement(1454..3343)
                     /locus_tag="VQT46_000078"
     CDS             complement(1454..3343)
                     /locus_tag="VQT46_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET2370190.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGGEKALQVGMG
                     ALTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDQAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSLFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            3481..5046
                     /locus_tag="VQT46_000079"
     CDS             3481..5046
                     /locus_tag="VQT46_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2370191.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKKPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKAIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            5046..5810
                     /locus_tag="VQT46_000080"
     CDS             5046..5810
                     /locus_tag="VQT46_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2370192.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEEIAKENLEKVGMGERYWQARPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLILNENQRAN"
     gene            complement(6009..6224)
                     /locus_tag="VQT46_000081"
     CDS             complement(6009..6224)
                     /locus_tag="VQT46_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370193.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNHEKFED"
     gene            complement(7095..8345)
                     /gene="ilvA"
                     /locus_tag="VQT46_000082"
     CDS             complement(7095..8345)
                     /gene="ilvA"
                     /locus_tag="VQT46_000082"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET2370194.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(8395..8751)
                     /locus_tag="VQT46_000083"
     CDS             complement(8395..8751)
                     /locus_tag="VQT46_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2370195.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(8989..9225)
                     /locus_tag="VQT46_000084"
     CDS             complement(8989..9225)
                     /locus_tag="VQT46_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370196.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(9332..10354)
                     /gene="ilvC"
                     /locus_tag="VQT46_000085"
     CDS             complement(9332..10354)
                     /gene="ilvC"
                     /locus_tag="VQT46_000085"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET2370197.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVVEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(10420..10896)
                     /gene="ilvN"
                     /locus_tag="VQT46_000086"
     CDS             complement(10420..10896)
                     /gene="ilvN"
                     /locus_tag="VQT46_000086"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET2370198.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(10889..12589)
                     /locus_tag="VQT46_000087"
     CDS             complement(10889..12589)
                     /locus_tag="VQT46_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET2370199.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(12790..14457)
                     /locus_tag="VQT46_000088"
     CDS             complement(12790..14457)
                     /locus_tag="VQT46_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET2370200.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(14460..14825)
                     /locus_tag="VQT46_000089"
     CDS             complement(14460..14825)
                     /locus_tag="VQT46_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2370201.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(14982..15170)
                     /locus_tag="VQT46_000090"
     CDS             complement(14982..15170)
                     /locus_tag="VQT46_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET2370202.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(15286..15462)
                     /locus_tag="VQT46_000091"
     CDS             complement(15286..15462)
                     /locus_tag="VQT46_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2370203.1"
                     /translation="MDSDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     DGMWRAENVTQDLI"
     gene            complement(15573..15722)
                     /locus_tag="VQT46_000092"
     CDS             complement(15573..15722)
                     /locus_tag="VQT46_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HET2370204.1"
                     /translation="MDKVETTIKSLCVHHYNLKFYVFNDDLPREWFQLMEKRLETLNS
                     EIVNV"
     gene            complement(16034..17578)
                     /locus_tag="VQT46_000093"
     CDS             complement(16034..17578)
                     /locus_tag="VQT46_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET2370205.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVINAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            17791..18093
                     /gene="gatC"
                     /locus_tag="VQT46_000094"
     CDS             17791..18093
                     /gene="gatC"
                     /locus_tag="VQT46_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET2370206.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            18093..19559
                     /gene="gatA"
                     /locus_tag="VQT46_000095"
     CDS             18093..19559
                     /gene="gatA"
                     /locus_tag="VQT46_000095"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET2370207.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDANNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDTKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            19559..21001
                     /gene="gatB"
                     /locus_tag="VQT46_000096"
     CDS             19559..21001
                     /gene="gatB"
                     /locus_tag="VQT46_000096"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET2370208.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDLHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMIAIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            21130..21690
                     /gene="efp"
                     /locus_tag="VQT46_000097"
     CDS             21130..21690
                     /gene="efp"
                     /locus_tag="VQT46_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET2370209.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            21712..22101
                     /locus_tag="VQT46_000098"
     CDS             21712..22101
                     /locus_tag="VQT46_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2370210.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGVYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            22094..22516
                     /gene="nusB"
                     /locus_tag="VQT46_000099"
     CDS             22094..22516
                     /gene="nusB"
                     /locus_tag="VQT46_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET2370211.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTNVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKVGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(22565..22942)
                     /locus_tag="VQT46_000100"
     CDS             complement(22565..22942)
                     /locus_tag="VQT46_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2370212.1"
                     /translation="MVLSNGQPTFLSTILSFVLLVIIGPVFEETLDRGYFMNTFFPKS
                     KYYLDVILSGLIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDNLRLTILCHSFF
                     NFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(23283..23468)
                     /gene="briC"
                     /locus_tag="VQT46_000101"
     CDS             complement(23283..23468)
                     /gene="briC"
                     /locus_tag="VQT46_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET2370213.1"
                     /translation="MTGTETFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRTG"
     gene            complement(23627..24394)
                     /locus_tag="VQT46_000102"
     CDS             complement(23627..24394)
                     /locus_tag="VQT46_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET2370214.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(24391..25257)
                     /locus_tag="VQT46_000103"
     CDS             complement(24391..25257)
                     /locus_tag="VQT46_000103"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET2370215.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(25294..26661)
                     /gene="accC"
                     /locus_tag="VQT46_000104"
     CDS             complement(25294..26661)
                     /gene="accC"
                     /locus_tag="VQT46_000104"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET2370216.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(26673..27095)
                     /gene="fabZ"
                     /locus_tag="VQT46_000105"
     CDS             complement(26673..27095)
                     /gene="fabZ"
                     /locus_tag="VQT46_000105"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET2370217.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(27092..27577)
                     /locus_tag="VQT46_000106"
     CDS             complement(27092..27577)
                     /locus_tag="VQT46_000106"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET2370218.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(27580..28815)
                     /gene="fabF"
                     /locus_tag="VQT46_000107"
     CDS             complement(27580..28815)
                     /gene="fabF"
                     /locus_tag="VQT46_000107"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET2370219.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(28837..29568)
                     /gene="fabG"
                     /locus_tag="VQT46_000108"
     CDS             complement(28837..29568)
                     /gene="fabG"
                     /locus_tag="VQT46_000108"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET2370220.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVIAIDGGLSM"
     gene            complement(29602..30522)
                     /gene="fabD"
                     /locus_tag="VQT46_000109"
     CDS             complement(29602..30522)
                     /gene="fabD"
                     /locus_tag="VQT46_000109"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET2370221.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(30515..31489)
                     /gene="fabK"
                     /locus_tag="VQT46_000110"
     CDS             complement(30515..31489)
                     /gene="fabK"
                     /locus_tag="VQT46_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET2370222.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVE
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(31608..31832)
                     /locus_tag="VQT46_000111"
     CDS             complement(31608..31832)
                     /locus_tag="VQT46_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2370223.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(31892..32866)
                     /locus_tag="VQT46_000112"
     CDS             complement(31892..32866)
                     /locus_tag="VQT46_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET2370224.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGEELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANNRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(32866..33300)
                     /locus_tag="VQT46_000113"
     CDS             complement(32866..33300)
                     /locus_tag="VQT46_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2370225.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(33394..34179)
                     /locus_tag="VQT46_000114"
     CDS             complement(33394..34179)
                     /locus_tag="VQT46_000114"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET2370226.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            34504..35868
                     /locus_tag="VQT46_000115"
     CDS             34504..35868
                     /locus_tag="VQT46_000115"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET2370227.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            35871..36242
                     /locus_tag="VQT46_000116"
     CDS             35871..36242
                     /locus_tag="VQT46_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET2370228.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIAREKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            36456..37730
                     /gene="serS"
                     /locus_tag="VQT46_000117"
     CDS             36456..37730
                     /gene="serS"
                     /locus_tag="VQT46_000117"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET2370229.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGTDEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(37755..38654)
                     /locus_tag="VQT46_000118"
     CDS             complement(37755..38654)
                     /locus_tag="VQT46_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET2370230.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPALSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(38764..39312)
                     /locus_tag="VQT46_000119"
     CDS             complement(38764..39312)
                     /locus_tag="VQT46_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET2370231.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(39530..40852)
                     /locus_tag="VQT46_000120"
     CDS             complement(39530..40852)
                     /locus_tag="VQT46_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET2370232.1"
                     /translation="MLELLKSIDAFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPAITALVLSVFVAIAVFGGLKSISKVSTTVVPFMALIYI
                     LGTLTVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGARFIWLYRVFFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(40943..41031)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(41195..43531)
                     /locus_tag="VQT46_000121"
     CDS             complement(41195..43531)
                     /locus_tag="VQT46_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET2370233.1"
                     /translation="MNKKILETLEFDKVKALFDPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QSFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVHFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(43635..44183)
                     /locus_tag="VQT46_000122"
     CDS             complement(43635..44183)
                     /locus_tag="VQT46_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET2370234.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIFYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(44180..44482)
                     /gene="zapA"
                     /locus_tag="VQT46_000123"
     CDS             complement(44180..44482)
                     /gene="zapA"
                     /locus_tag="VQT46_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET2370235.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            44569..45450
                     /locus_tag="VQT46_000124"
     CDS             44569..45450
                     /locus_tag="VQT46_000124"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET2370236.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQLVEENRGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TSDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLSFC
                     AKLHFKNTEKAKKRLER"
     gene            45454..46068
                     /gene="lepB"
                     /locus_tag="VQT46_000125"
     CDS             45454..46068
                     /gene="lepB"
                     /locus_tag="VQT46_000125"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET2370237.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            46127..46270
                     /locus_tag="VQT46_000126"
     CDS             46127..46270
                     /locus_tag="VQT46_000126"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HET2370238.1"
                     /translation="MFIDKYSTKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVA
                     DGS"
     gene            46347..48713
                     /locus_tag="VQT46_000127"
     CDS             46347..48713
                     /locus_tag="VQT46_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET2370239.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTHLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(48761..50044)
                     /locus_tag="VQT46_000128"
     CDS             complement(48761..50044)
                     /locus_tag="VQT46_000128"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET2370240.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     EDGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(50238..50597)
                     /locus_tag="VQT46_000129"
     CDS             complement(50238..50597)
                     /locus_tag="VQT46_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2370241.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(50896..51525)
                     /locus_tag="VQT46_000130"
     CDS             complement(50896..51525)
                     /locus_tag="VQT46_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2370242.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPTVSPSQEPFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYPSYNFKVHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(51570..51809)
                     /locus_tag="VQT46_000131"
     CDS             complement(51570..51809)
                     /locus_tag="VQT46_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370243.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPGSNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(51959..52225)
                     /locus_tag="VQT46_000132"
                     /pseudo
     CDS             complement(51959..52225)
                     /locus_tag="VQT46_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(52250..52558)
                     /locus_tag="VQT46_000133"
     CDS             complement(52250..52558)
                     /locus_tag="VQT46_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2370244.1"
                     /translation="MDWDFADTCWEKEPRKYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHPELEEIILILFENLFKPRQLYLQPQNSVLRLQIAS
                     "
     gene            complement(52483..52725)
                     /locus_tag="VQT46_000134"
     CDS             complement(52483..52725)
                     /locus_tag="VQT46_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET2370245.1"
                     /translation="MSLADLLEELEAAKDSKKARPMEAYMRHQFSFLGIAVPERNKLY
                     KNIYQKRKKQRLSIGILQTLAGKRSLENTNMWLLTI"
     gene            complement(52726..53358)
                     /locus_tag="VQT46_000135"
     CDS             complement(52726..53358)
                     /locus_tag="VQT46_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2370246.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(53372..54367)
                     /locus_tag="VQT46_000136"
     CDS             complement(53372..54367)
                     /locus_tag="VQT46_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2370247.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLYDVEKTEK
                     FVFLLLVFSMSMTCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVVDPDLDASFKS
                     LSGKLNLLTEALQKAENHSLDQEEEIIEKERKRIARDLHDTVSQELFAAHIILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFRLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(54364..55062)
                     /locus_tag="VQT46_000137"
     CDS             complement(54364..55062)
                     /locus_tag="VQT46_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET2370248.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(55140..56150)
                     /locus_tag="VQT46_000138"
     CDS             complement(55140..56150)
                     /locus_tag="VQT46_000138"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET2370249.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSKQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKAVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(56134..57141)
                     /locus_tag="VQT46_000139"
     CDS             complement(56134..57141)
                     /locus_tag="VQT46_000139"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET2370250.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLTPNPDYSLIQETIALMGDFLAVRGQNLRSFSLEICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYDVSVDQELLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFSISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKSEKIIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(57128..58081)
                     /gene="mvaD"
                     /locus_tag="VQT46_000140"
     CDS             complement(57128..58081)
                     /gene="mvaD"
                     /locus_tag="VQT46_000140"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET2370251.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVIADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YSVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(58063..58941)
                     /gene="mvk"
                     /locus_tag="VQT46_000141"
     CDS             complement(58063..58941)
                     /gene="mvk"
                     /locus_tag="VQT46_000141"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET2370252.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(59063..59392)
                     /locus_tag="VQT46_000142"
     CDS             complement(59063..59392)
                     /locus_tag="VQT46_000142"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2370253.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFSKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMIPHDFPLYLTVWSFFRRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVQ"
     gene            60054..60390
                     /locus_tag="VQT46_000143"
                     /pseudo
     CDS             60054..60390
                     /locus_tag="VQT46_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
     gene            60290..60877
                     /locus_tag="VQT46_000144"
     CDS             60290..60877
                     /locus_tag="VQT46_000144"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370254.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCEIAY
                     ALFAYSKVLEPSMFYNDLHTFHAELKKLLEKVTSNTENLGNLQLSWCEGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVILA
                     CSERDDHGLLMFQGDSGKADLFDFGIGSRGYIGVY"
     gene            60920..62152
                     /locus_tag="VQT46_000145"
     CDS             60920..62152
                     /locus_tag="VQT46_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2370255.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVHIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLFALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFVTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(62270..63226)
                     /gene="cbpC"
                     /locus_tag="VQT46_000146"
     CDS             complement(62270..63226)
                     /gene="cbpC"
                     /locus_tag="VQT46_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET2370256.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLRSSGAMA
                     TGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSSGAMATGWYQDGSTWYYLNAGN
                     GDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYNGEWVR"
     gene            complement(63324..64013)
                     /locus_tag="VQT46_000147"
     CDS             complement(63324..64013)
                     /locus_tag="VQT46_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2370257.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            complement(64025..65449)
                     /gene="gndA"
                     /locus_tag="VQT46_000148"
     CDS             complement(64025..65449)
                     /gene="gndA"
                     /locus_tag="VQT46_000148"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET2370258.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVSDVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEDQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            complement(65525..66919)
                     /gene="mapZ"
                     /locus_tag="VQT46_000149"
     CDS             complement(65525..66919)
                     /gene="mapZ"
                     /locus_tag="VQT46_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET2370259.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTNSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLVTQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            complement(66932..68089)
                     /locus_tag="VQT46_000150"
     CDS             complement(66932..68089)
                     /locus_tag="VQT46_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET2370260.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARLPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERKLELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            complement(68174..68554)
                     /gene="rnpB"
                     /locus_tag="VQT46_000151"
     ncRNA           complement(68174..68554)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQT46_000151"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(68575..68904)
                     /gene="gpsB"
                     /locus_tag="VQT46_000152"
     CDS             complement(68575..68904)
                     /gene="gpsB"
                     /locus_tag="VQT46_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET2370261.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            complement(68974..69501)
                     /locus_tag="VQT46_000153"
     CDS             complement(68974..69501)
                     /locus_tag="VQT46_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET2370262.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            69567..70163
                     /gene="recU"
                     /locus_tag="VQT46_000154"
     CDS             69567..70163
                     /gene="recU"
                     /locus_tag="VQT46_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET2370263.1"
                     /translation="MINYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            70160..72319
                     /locus_tag="VQT46_000155"
     CDS             70160..72319
                     /locus_tag="VQT46_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HET2370264.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGIYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(72486..77789)
                     /locus_tag="VQT46_000156"
     CDS             complement(72486..77789)
                     /locus_tag="VQT46_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HET2370265.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATANENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLFSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKTPGNSTWYKGNRVVAPEPGSVNRLSITLKSDGQLNASNNDVNLFDTVTLPGAVN
                     DNLKNEKKILLKAGTYGNDRTVVSVKTDNQEGVKADDTPAQKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVFLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVNDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDQAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLVSDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLASVSLALSALFVVKTKKD"
     gene            complement(78090..80072)
                     /locus_tag="VQT46_000157"
     CDS             complement(78090..80072)
                     /locus_tag="VQT46_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370266.1"
                     /translation="MKSSKLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDDQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQGSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
BASE COUNT        23431 a        18282 c        14855 g        23829 t
ORIGIN      
        1 tctaaccaca gcttttgttt caattggtaa tgagtttgat aacgcataga cgtttgatct
       61 cgtctaaggt aacaaggcaa aaaattcgtg gataaccaag tagacttgaa atactatatc
      121 tggaggtact cccatgcttt atgtgggcat tgatatcgct aaaaataaac acgatgttac
      181 agccttgaat gttccaggaa aaactgttct taaaccactc actttttcaa ataataaagc
      241 tggttttgaa ctcttagatc tgtctcttcg acagctcaac caagactgtc tcatcgctct
      301 tgaaaatacc ggacattatg cctttaatct actgaacttc ctgcatgaac aaggatataa
      361 agtttacacc tacactcctt tgctcatcaa ggaatttgcc aaatcattat cacttcgcaa
      421 gactaaaacg aataagaaag acgctcatgg catcgctctt aaacttcttt ctgaccccaa
      481 tcgtgaacaa tttcaacacg ataatcggca agtagaacta aaaatactgg ctagacatat
      541 tcatcgtctc aagaaaaaac agtctgattg gaaagtacaa tacactcgtt gtcttgatat
      601 catctttcct gagttggata aaatcgttga aaagcattca gaatatacct accaactctt
      661 gacatgctac cctaatcctc agaaaaggct tgaggcagga tttgataagc tgatagaaat
      721 taagcgattg accgcttcta aaattcagga tatcctctca gttgcacctc gttctatcgg
      781 aacaacatct cctgctcgtg aattcgaaat catcaaacat tacaagaggc tcattgacaa
      841 ggcggaaaca tgtgtcaatg acttgatggc tgagttcaac tcggtcatca cgacggtcac
      901 tgggattggg aatcgtttag aggcggtcat tttagccgag attcgaaata ttcatgcctt
      961 tgataatcct gctcaattac aagctttcgc tggactggat tcttctattt atcagtcagg
     1021 tcagattgat ttagctggaa gaatgatcaa acggggttcc cctcatctgc ggtgggcact
     1081 catacaagct gccaaagcat gccctcgctt ttcacctgct tttaaggcct atcttaagac
     1141 taagttagaa taaggaaaac attacaatgt agccatcatc caccttgcaa aaaaacttat
     1201 ccgaaccctg ttttatatcc taaaaaagag ctgccatttg acgaacaaaa agtgatgtaa
     1261 tttctgaaat taacacagga ttacctttga aaaaatggac tttttcaagg gctttttgcc
     1321 gtgctctaaa atcatcgcca aatcatcaaa ttgaaataag aaatagttta gataaaacta
     1381 ttgacttttc ttatagtttg tcttttttct atcttccatt atatcatact ttttcagtct
     1441 atggtagctc tctttaaaag gcaccgatac tgccgccacc tccgcctcca gagaagccac
     1501 caccagaact tccacttcca gaagatacag agtaggtgct tgctgtattt gcgacactag
     1561 cataatggct catttgcgcg cttgaatgat aaaacagact gtgccagcca taagctacat
     1621 agagattgat atctggattt tccacttgaa tctgatgaac cttcatcaaa tgactaacct
     1681 tgtccgcata gccaaataag gtcgcataga ccaagaggcg attccagacc acaatacttt
     1741 ccagttcagc ctgatccaat cgtgcaatct cacgcaacat attttcaaaa ctggtccaga
     1801 gatagtagac ctcagctccc gcttcattta gaacaccatc acgattatct agtcgaagct
     1861 tccaataata gaaaacagac aaaactaacc ctagaaaacc aagtattggc aaagggaggt
     1921 aaagatagcc atgaacgtct aaactgtaca agaacaaacc aaatccgata aataggggca
     1981 ggatagtcaa ggcacccata cccacttgca aggccttttc cccaccagtt aaaggacgat
     2041 aataatctgg gagcccccag aaggaaactc gttttctcac tccttcttgc atctggttca
     2101 atacctcttc aaaagaagat ttgagttgaa gccctcttgc ttgaatccgt ttttcatcag
     2161 aaactttggc tctacgataa agactatcag ataccttgta atccgcaaac aaattggaaa
     2221 gagtttcttc ttttttacct gaaaaagcta gatttaggca gtctttctca aagcttgaca
     2281 aaccatcttc ttttactagc ctcaaaccaa ctgcatctcc ttctgaaatg atagagacat
     2341 tcccacggtc tatcacatct agcaaggtag cttgaataag ttgatcaaag gtgaattttc
     2401 cagctccctt gaccaaggga ctcacttcct ccaaggaggt cgagtagact gcttctgata
     2461 aaaccatagg ctctaattcc attggtggtt catagagacg atgatttttg gcatatttga
     2521 ctgaaggagt ggtctttctt ctataaataa aatagaagca gacactcaat aacaaggaga
     2581 tagaaaggat cgaagggagg acccaagtaa caagttgttt actctgatct ttttctctaa
     2641 caatcgagtc ttctatctta ttaaactctt ctaaacgatt ccctttcaat ccctgatccc
     2701 tagcgctagc aaaatcggtc cgaggccaat aggcatgcaa ctcaactcca cgcttagccg
     2761 gaagattgtc taaacggata gtataatcaa ggttactctt ttcaatcgtt ccctctctaa
     2821 aaagtttccc tgtatggaaa aagagttttt cagctccctt gtctcccctt acatgaaatt
     2881 caaacttttc aatagactct gaactatctg tcagaggttg ccaatttaat tcagcgatat
     2941 catcataaag gaaaagtaaa ttttttaagt tccagacgag gtcaacttca actatgtcgc
     3001 cctcctgacc tggattatag actctcacag tataaccatc cgcttcttct gttacttcgc
     3061 tagtcacatc tgctagttct gcaccgtttt tcgcggcctg aacctttgga tgagggtcaa
     3121 tgtcaaaccc gctaggcatc ttaccagcac gtccaagtcc cacgatttgt cccttaaagt
     3181 cctcctcaaa ctggtaaact atcttctgtc taaactctgc cgtattatct gcatgaatat
     3241 acaaatcccc ttgataagag tttatcttga aatcaatggc aaaaacagag agtggaagaa
     3301 ggcaaaacaa gcctaacacc agtaagaaaa aagttttttt catcaactaa gccccctttt
     3361 tatctttctt atcattatag cattttttcg taagtaaagg cttacttatg ttgaaaaatt
     3421 acgcattttt cgataaaata ggagacagtt attttttaat agatcagaat aggagaaatc
     3481 atgagaaaaa tatacttatc tattttcaca agtctcttgc tgatgctagg acttgtcaat
     3541 gttgctcaag ccgatgaata tttacgcatc gggatggaag cagcatatgc tccctttaac
     3601 tggacccagg atgatgatag caacggagct gtcaaaatcg atgggaccaa tcagtatgcc
     3661 aacggatacg atgttcaaat cgccaagaaa atcgctaagg acttaggtaa aaaacctttg
     3721 gttgttaaaa ccaagtggga aggtctagtc cctgccctta cttctggtaa gattgacatg
     3781 attatcgcag gtatgagtcc aactgcagaa cgcaaacaag aaattgcctt ttcgagcagt
     3841 tactacacta gcgaaccagt tttgcttgtc aaaaaagatt ctgcctacgc aagtgctaaa
     3901 tctttggatg actttaacgg tgcaaaaatc acttctcaac aaggggtcta cctctacgac
     3961 ttgattgcac aaatcccagg tgctaaaaaa gaaacagcca tgggagactt cgctcaaatg
     4021 cgacaagctc ttgaggctgg tgtcattgat gcttatgttt ctgaacgtcc agaagcactg
     4081 actgctgaag ctgcgaactc taagttcaag atgattcaag tagaacctgg tttcaaaact
     4141 ggggaagaag atacagctat cgctatcggg cttcgtaaaa atgacaatcg tattagccaa
     4201 atcaatgcca gcattgaaac catttcaaaa gatgaccaag ttgccttgat ggatcgtatg
     4261 atcaaggaac aacctgccga agctacaaca actgaagaga ctagcagtag tttctttagc
     4321 caagtcgcta aaattctttc tgaaaactgg caacaactct tgcgtggtgc tggtatcact
     4381 cttttaatct ctatcgtcgg aaccatcata ggtctcatta ttggacttgc cattggtgtc
     4441 ttccgtactg ctcctctctc tgaaaacaaa gccatttatg gccttcaaaa actagtcggc
     4501 tgggttctca atgtctacat tgaaattttc cgtggtacgc caatgattgt tcaatcgatg
     4561 gttatctact atggaactgc ccaagctttc ggtatcaacc ttgaccgtac actagctgct
     4621 atcttcatcg tttcaatcaa taccggtgcc tacatgactg aaattgtccg tggtggtatc
     4681 ctggcagttg acaagggaca atttgaagct gcgactgctc ttggtatgac tcataaccaa
     4741 accatgtgta agattgtcct acctcaggtt gtccgcaata tcctaccagc aactggtaat
     4801 gaatttgtca tcaatatcaa agatacatct gtattgaacg ttatctctgt tgtcgaactt
     4861 tatttctcag gaaataccgt ggcaacacaa acctatcaat acttccagac atttacaatc
     4921 atcgccgtga tttactttgt cctcaccttc accgtaacac gtatcctacg ctttatcgag
     4981 cgcagaatgg acatggatac ctacactaca ggtgctaacc aaatgcaaac ggaggatttg
     5041 aaataatgac acaagcaatc cttgaaatta aacacctcaa aaaatcctat ggacaaaacg
     5101 aagtgctaaa agacatttct ctcactgtcc acaagggaga agttatttct atcatcggaa
     5161 gctctggaag tgggaaatca accttcctac gctccattaa cctacttgaa acgccaactg
     5221 atggacaaat cctttatcat ggacaaaacg tcctcgaaaa aggctatgac ctcacgcaat
     5281 accgtgaaaa gttagggatg gttttccaat cctttaacct ctttgaaaat ctcaacgttc
     5341 ttgaaaacac aatcgtcgct cagacaactg tccttaaacg cgaacgcaca gaagctgaag
     5401 aaattgccaa agaaaacctg gaaaaggtcg gcatgggaga acgctactgg caagcgagac
     5461 ccaaacaact ctcaggtggt caaaaacaac gtgtggccat cgctcgtgcc ctttcaatga
     5521 atcctgacgc cattctcttt gatgaaccaa catcagctct cgatccagaa atggttggag
     5581 aggtcctcaa aatcatgcaa gatctggctc aggaaggctt gaccatgatt gtcgtaaccc
     5641 atgaaatgga atttgcccgt gatgtctctc accgtgttat ctttatggat aagggtgtga
     5701 ttgctgaaga aggtaaacca gaagacctct tcactaatcc taaagaagac cgtacaaaag
     5761 aatttcttca acgttatctc atactcaatg aaaatcaaag agcaaactag gcagctagcc
     5821 gcaggttgct caaaacactg ttttgaggtt gcagatagag ctgacgtggt ttgaagagat
     5881 tttcgaagag tatcaaataa aaagaaaagg ctgcatcaac cgtgcagtct ttttgctgtc
     5941 ctcaaaatga aaaggcagat tctctatctc tactacttga aggtcaagaa tccaccgtta
     6001 tccaaagatt aatcttcaaa tttttcatga tttttttcat agaaatcaat taagcctagg
     6061 gctgtttcaa atgaaatatt ttttactttt gcacgaccct gcgccagagc aatgatagac
     6121 atttcacgcg cattcgtttc tttagagata cggtagcctg tgattttctt atcacgaacc
     6181 cagccaacaa ctgattctac tttttcaaag tttgacttag ccatgttttt ctcctatttt
     6241 cttctttata atatttaatt gtatacgttt ttactacttt tgtcaataaa aaaaacatat
     6301 attcaacgaa aataattagt tcagaatttt cttacttcct ttttaaatcc gataatatat
     6361 aggttttgct agcctctaca ccataaatat ttgctaataa aaatactgta ttattaccct
     6421 cttaaggtgc aaaattattc aagttcttaa aaaatgcttc tctatttccg taagatagct
     6481 tatttcttcg atttaagaac tgaagatgat agttctaacc tttagaaatc caagccttct
     6541 ctagctcaaa aactcctatc tttcttcctc aataaatcat ctgagagata ggtattcctt
     6601 atatccttca aattcatcac tcctttggat attgaggtgc tagcctagaa gcagacaccc
     6661 gattatctaa accatcctta atagagatga caagacagat aagctcagtt aattacttat
     6721 atatcttttt aatatggtat atttgtcaac aaaaagaaat caaatcatac cttatactca
     6781 atgaaaatca aagagcaaac taggaagcta gccgcaaatt gctcaaaaca ctgttttgag
     6841 gtttcagata gagctaacgt ggtttgaaga gattttcgaa gagtattaaa gacagtatga
     6901 ctatgcttgt caatagatag gaaatcaaaa tgaaggatgg aaatctgagc caaacatcat
     6961 aagtgctata atgaacagaa gtaagaattg cacgataagt tttctaaaac cataggaatc
     7021 gtcccctttc ttcatcttca ttatagcaca tatacatcag ttgtacaaat aatatgatat
     7081 ttttttatta gtcctcagac aagcatatta taaagcgttt cattaccatt taagttaata
     7141 taagctggat caaaaccttc cattctacgg atcaaacctg cataatcatg cttatctgcc
     7201 aaagcgatcc caatcaatac tgggcctgtt cccttgctag ctcgtttgat atactcaaaa
     7261 cgtgtgatat catcatttgg ccccaggata tcatttacaa actcacgcaa agctcctgga
     7321 cgctgtggga aattgaccac aaagtaatgt ttgataccat cataaatcaa ggcacgctct
     7381 tccatttctg gcatacggtt gatatcatta tttcctccag aaatgataca acaaatggtt
     7441 ttccccttaa tatattcagc taaaacctct aaagaggcga tactagccgc tccagcaggt
     7501 tctgcgacta tcccttgctt agagtaaagg tcaatcaagg tttcagaaat caatccctca
     7561 tcgacaccta ccaaagtttg aatatgttga cgagttgctt cataggtcaa ctgacctacc
     7621 ttttgcacag caatcccatc cgcaaattta tcaatttcct tgagtttgac tggacctcca
     7681 gcctcaaagg cagctttcat ggaacgcgct ccattcgcct ctactccgat aacctcaatc
     7741 tctggacttg tttccttgat ataggtagaa accccggcaa tgagaccgcc accaccaaca
     7801 ggaaccaaga cagcatcaaa atcaatcgat tcttttcgag cttcttctaa aatctcataa
     7861 gcaactgttc cttgacctgc ttgaacatga gcatcatcaa aaggatcaat aaaggtacga
     7921 ttttcagaga ctgtaaattc ttgagctgct ttggctgagg catcaaaggt atctccaact
     7981 agtttaatag ttacaaaatc cccaccaaaa aagcgaacct gaccaatctt ttgttgtggc
     8041 gtagtaatag gcataaagat agtagcagga attttcattt cattacaagt ataggctact
     8101 ccctgcgcat gatttcccgc agaagcgcag actaccccac gttcacgttc ttccttgctg
     8161 agctgggaaa tggcataata ggcaccacga attttaaagg agcgaacacg ctgggcattt
     8221 tcttttttca aataaatctt agcaccatac ttctccgata aataatgatc gtaatccagt
     8281 ggagtattca caaccacacc gttcaagacc ttgtgagcct tgattatatc ttttgaactt
     8341 aacatataaa acctcttttt ctataaaaaa cagtcactaa tgactgtttt ttagttattc
     8401 atctccgaaa acttcagtaa cactttcatg gtatttatga gccatacgaa tcgaaaactc
     8461 tttaggaagt tcataacgat ttgtggaaat ccaatcatat aaccattcta ccaaactttc
     8521 ttcactatca ttacgatgga agataaaata gtttaaaatt tctttatatt ctacatcatt
     8581 caaatccaac gtgtctacaa attgactacg aggaacaaaa ttagaatcta attttcttag
     8641 ttgatctgtc aattctccca attgtaaatc caactgaaaa aatagttttt gcagttgcct
     8701 atcagtttca tcacatcctg tcttgataga aaacaaattg gtaatattca tatgatttca
     8761 acccctaaat aagtacatct aatatcccac gaatagctga agctaaagtt ttcgcagtcc
     8821 agtcatttaa acccgattct ttcaatccag atgcaataat ttgctctatt tgatataaac
     8881 cgccatctat cgtctcattt attctgcgaa gaggaccttc aatataggat aaagcttctc
     8941 cgaatctaac agctgattta ggtcctaatg atttaccaac tatatttgtt aatgtttttt
     9001 atttctcaaa atccatttcg ctatataacg agcagattta gtcgcaccag ctctctcaaa
     9061 cggagaatga atttcaagac cttcttctct agctatttgt gccaatttga agaattgttc
     9121 aaaggtcata tgcaacctac catcttcaaa attagcatca tcataaatgt taattacagc
     9181 attttcatca tacgaccaat ctgctttatt ttggtctgct agcactatta ccgacggtgt
     9241 aattacatta tacaactaga accaataata acgatgcaat ttttctcata atctttttca
     9301 taaaatcatc tccagcgcta tatatttcta attagttata gattttgaat gcatcatcgt
     9361 cgtttttacc aacaaatggc attgctttac gcaattctgc accaactttt tcaatttcaa
     9421 ggttagctgc ttgttcacgg taagcagtca attttggacg tccagcttta tagtcattta
     9481 caaagtcatt tgcaaattta ccattttgga tgtctgccaa gacagccttc atattttctt
     9541 taacttgttc agtgattaca cgtggacctg atacatagtc accgtattca gcagtgtttg
     9601 aaatagattg acgcattttc ttgaatccac cttcgtagat caagtcaacg atcaatttca
     9661 tttcgtgaag aacttcaaag taagccaatt ctggagcgta acctgcttct gtcaagactt
     9721 cgaaacctgc ttcgataagg gcagtcaaac caccacaaag tacagcttgt tcaccaaaca
     9781 aatcttcttc agtttcttct ttgtaagttg tttcaagaag acctacacga gccgctccaa
     9841 cacctttaca ccagtccata gcaatgtttt tagcatttcc tgttgcatct tggtatactg
     9901 cataaagagc tggaacacca aatccttctt cgtaagtacg acgtaccaag tgtcccggtc
     9961 ctttaggagc acacatgaag acatctacat ccgcaggaac tttgataaat tcaaagtgga
    10021 tgttgaaacc atgggcaaat ccaactgcgt ttccagcttc caagtttgga gcgatttctg
    10081 cttcgtacaa ttcttgttga atttcgtctg gcgccaagat catgataaca tcagccaact
    10141 tagtagcttc tactactgtg taagtatcaa atccatcttc ttttgcttta tcaaaagatt
    10201 tacctggacg tacaccgata ataacgtcac gacctgaatc acgcaagttt tgagcatgcg
    10261 catgtccttg tgaaccataa ccgataacgg cgattttttt accgtcaagt gctgctactt
    10321 taacatcttt ttcatattcc atttgaactg tcatagcttt tctctctttt ctattattta
    10381 ttgcctttta ggctggttta ataaatttaa gttggatttt taatcgcggg taaatccagt
    10441 tgcacccgtt cgagcaatat tgcgaatacc gtatgggcga atgactcgca atagggcttc
    10501 gctcttttct gcatttcccg tcatctgaat ggtaatcgag cttggcgcta cgtctaccac
    10561 tgttgcacgg aaaggttgaa taatcgctaa aatctcagct ctcttctcag ctggcgctga
    10621 catcttaacc aaaatcacct cgcgctccaa atgaggcttg tctgtaatat ctcgaatgcg
    10681 aatcacatca atctgacgat tgagctgttt gatgatttgc tccacttcat catgagaagc
    10741 aacatcaata ataatagtga tacgcgatac attcggatct tctgttgctc caacagagat
    10801 gctttcaata ttaacctgac gacgagatag gacacctgta aagcgattga ggactcctga
    10861 acgattttgt agttttgctg ttaacattct acgcatggaa ctgcaccccc aacatctcat
    10921 gattactctt accagccggt accattggta acacctgttc cttacgagaa atatctacct
    10981 caattagcat aggaacatcc tcagtgatga cttcaaggtc ttgagccaag gtctcaggat
    11041 tgtcaaactt atagttttta ataccataag cctgcgccat caattggaaa tcaggaaggg
    11101 tatcaaagac cgactctgat gttctgcctt catagaagga ttcctgccac tggcgaacca
    11161 ttccaagtga atgattgttc agcataacca ccttgattgg caccttgtaa atattcaaaa
    11221 tagccaactc ctggttggtc atttggaaac caccatcccc aacaaacaag actacttcct
    11281 tatctgggtt agcaatttta gcaccgattg ctgctggaat tccaaagccc attgttccca
    11341 aaccacctga agtcactaac tgacgctcat tttggtaggg ataatactga gctgtccaca
    11401 tttggtgttg accaacgtct gttaccacaa tggcatctcc attcgtcaat tcaccaattc
    11461 gttcaataac tgcttgcggt tgaaccacac gctctttctt gtcataagaa cgaacacgat
    11521 tcttgtcttt agtgactttc tcaatccact tttcagtatt gttgtgaact gttggttctg
    11581 ctagcaacat ttgcaaggcc ttcttagcat ctccaactac aggaatgtct gcactgataa
    11641 tcttgccaat ctcagctggg tcaatatcaa tgtgggcaac cttagcattc ttagcgaaag
    11701 tcttaggatt ccccgtcaaa cggtcatcga aacgagaacc aatactaatc ataaagtccg
    11761 cttccgtcat ggcaatattt gctgcgaatg acccgtgcat gcctcccatt ccaagaaaga
    11821 gtgggtgact cgttgcaatc gttccttgtc ccaaaagact ggttaccact ggaatttgat
    11881 agcgttctgc aaattcattt agttccgtag cagcctcagc ataactaatt ccaccaccag
    11941 ctaacaagac tggcttttta gccttggaca attgcttcaa gattttcttg atttgcatat
    12001 cattcggctc aagagtcggc tgataacttg gtaaattcac ttctggtgaa taaatgaagt
    12061 ctgtttctaa agcagatatg tcttttggta ggtcaattac aactggccct ggacggcctg
    12121 tagttgcgat atggacagct tccgtaatga tacgcggaat atcagctgtc tcacgaactt
    12181 ggtaattgta cttagtgatt ggcatggtaa ttcctacgat gtctgcctcc tgaaaggcat
    12241 ccttcccaat ccctgctcgc gccacctgac ctgtaaagac caaaagggga acgctatcgc
    12301 tcatagcatc cgcaatccct gtaatggcat ttgttgctcc tggtccacta gtgacgacgg
    12361 caacacccaa ctttccagtt gatttggcat aaccttcagc ttcatgcaaa caaccttgct
    12421 catggcgccc tagaatgtgg cgaatgcctt taaaattata tatcgcatca taaaaaggca
    12481 aaaccgcacc accaggataa ccaaagatgg tatcaactcc taaatcacga agtgtttcca
    12541 aaactaggtc cgaccccgtc ttaggagatt ctaaactgat tttctccatt gttccccttt
    12601 ctttcctctt aaaaataact tgttactatc ataccatttt ttcaaaattt ttcaagataa
    12661 aagaagaaat tttctgaatt ttctatttta acgtttattt atgaatgtta tttttgtttt
    12721 tattaaaaag ataccgattt catttactaa aaaagaaaaa agaactgatt tctcagtcct
    12781 tcattaatct tattccacac taaataggta tgggtaaaca ggttgttgac cttggtgaat
    12841 ctcgacttca acgtcttcga attcttctac gatttcttga gcgatttcat tggcaagttc
    12901 ttcgcttccg tcttcaccga catagaaggt tacgatttca ctatcttcat ccaacatatg
    12961 tttcaaggtt tcagtcaatg tttggtgcat atcagggttt gacacaagaa tttttccatc
    13021 caccatacct agattatcgt tttcatggat ttctaagcca tcgatcgttg tatcacgcac
    13081 ggctgttgtg acgcttccgc taacgacatc gctaagagca gctgtcatac gctcttggtt
    13141 ttcttcaatg gacttgcttg gatcaaaggc aagaagactt gtcatacctt gaggaagagt
    13201 gcgagcctct accactactg ctggttgctc caaaacttct gccgcagatt gagctgccat
    13261 gaagatgttc ttgttgtttg gcaagaagat gatgttacgg gcattgacct gttcaacagc
    13321 cttgataaag tcttctgttg aagggttcat ggtttgaccg ccttcgataa cataatccac
    13381 gccttgagaa cagaagatat ctgctagacc tttaccagcc accacagcaa tcaaagcata
    13441 ctctttttct tcagccgact tgataacttg agtagcttct ttctcaacct gtgcttcgtg
    13501 ttggttacgc atattgtcaa cttttacctt gaccaagcta ccatatttga gaccttcttg
    13561 cataacaagt cctggatctt ctgtatgaac atggactttg acaatttcat catcgttaac
    13621 aacgaggaga gaatccccaa gctcatccaa gtagttacgg aattcatcgt agtcaaaatc
    13681 tttagcatag gttggacctt gcttaagagc taccatgatt tcagtacagt aaccaaacgt
    13741 gatgtcctca gtcgctacgt gaccagctac agacttatga tgctctacat tgatcatctc
    13801 actcatgttg gcaggagtcg ctacaaagtc ctcagatgca atatattcgc cagtaagggc
    13861 tgaaaggaaa ccttcgtaga tgaagaccaa tccttgacca cctgagtcca caacgccaac
    13921 ttctttcaat actggaagca tgtctggtgt tttagctaga gctgttttag caccttccaa
    13981 ggctgcgcgc atgacttcaa cagtgtcatc tgtttgctca gcttttttct tagcaccgat
    14041 agcagctcca cgagaaactg tcaaaatcgt tccttcaaca ggtttcatca ctgccttata
    14101 ggcaacttcc acacctgatt ggaaggccag agccaagtct tgacctgtta actcgtcttt
    14161 atccttgata gcttgggaaa atccacggaa aagctgagac gtaatcactc ctgagttccc
    14221 acgcgcaccc atcaaaagcc ctttggcaag aatgctcgct acttctccaa ctgtagaagc
    14281 tggcttgtct gcaacttctt tagcaccatt ttcaatggtc attcccatat ttgtcccagt
    14341 atctccatct ggaactggaa agacgtttaa tgaattgaca tattcagctt gcttattcaa
    14401 gcgagttgat gcagcctgca ccatttcttg aaataagcta gtagtaattt ttgacacggt
    14461 tattctccta caactttgat attttgaatg tagacattta cagtctgagc agtaattcca
    14521 agctggtttt ccaagctaaa ggcaacacgc tcttgaatgt tttttgacac ttcactaatc
    14581 tttgttccgt agcttaacac ggtatataca tcaactgcaa tactgccatc ttcggctgcc
    14641 tttacgacga cacctttaga ataattttcc ttacctagca gggcttggaa attatctttg
    14701 agggcatttt tactagccat accgaccaca ccaaaaatct cagttgctgc tccacctacg
    14761 acggttgcaa tcacttcatc tgttagttcg atttgaccat cttttgtatt aatttttaca
    14821 gtcatccttt ttacctcaac tagttgatac tctattttat catatttcag cccaagtgta
    14881 aaagcagaat gatgtatcag cggatattta ctctattttt caaacgatgt tatacccaca
    14941 ataaaagaaa aaagacccta aggtctcctt tgcttttatt attaaacgcg ttcaacttta
    15001 cctgatttca aagcacgagc tgaagcccaa acttttttag gtttaccatc gataagaaca
    15061 gtaacttttt gaaggtttgg ttttacggca cgttttgttt ggttcatcgc gtgtgaacgg
    15121 ttgtttcctg atacagtctt acgacctgta aagtaacata ctttagccat tgtgttttcc
    15181 tcctattaga tctaatatag cggatgtgct agcaccacat accgtactat gttatcacac
    15241 tttcttgttt tttgcaaggg aattggaaga ttttttattt gtgtcttaaa tcaggtcttg
    15301 cgtgacattt tctgctctcc acatgccatc gttgattaac agaacaccag aattaaaatt
    15361 atgtgtataa aaatcatctc taactgcagc taagggtata gccgtcaagt ccaaatccca
    15421 cagctcatct atcgattttc ttacaacaat atctgaatcc aaatacagta cacgagactc
    15481 gcttacatac tttggaataa aatacctaaa aaagccgcat atgaaagtcc ctcaaagggg
    15541 agacgataac ctttcagaat attactgtca atctaaacat tcacaatctc actattcaaa
    15601 gtctctagtc ttttttccat caattggaac cattctcgcg gaaggtcatc attaaaaaca
    15661 taaaacttaa gattataatg atgaacacaa agagatttta ttgttgtttc aactttatcc
    15721 atataagcat tatctgcacc taagacaatc gcttttttct cttttttctc ttctttcact
    15781 ttttatctca tttcttttta ttcccatcat atgtttctac gtaaccatta ttttcgccta
    15841 ttcgttcgta aaaccatacc agtggagatt ttagatgaag tcccattacg gtttacaatt
    15901 tttacattac gacacggagt tttacaaatc gatttcattt gccaaacgta gttagtgagg
    15961 cagttagcta gttcgccaaa tagcgactag cgtccaacaa tttggaactt tagttccaat
    16021 tgttggtact gagtcacatc ttctcctcta actctacgtc tggatacttg tcagcaaacc
    16081 agcggagggc aaagtcattt tcaaagagaa agactggttg gtcaaaacgg tctttggcta
    16141 agatattgcg acttgacgac atccgttcat ccaagtcctc aggcttgatc caacgaacgg
    16201 tctttttacc cattgggttc ataactactt ctgcattgta ctcgccttcc atgcggtgtt
    16261 taaagacttc aaactggagt tgacctacag cgcctagcat gtactcacct gtttggtaat
    16321 tcttataaag ctgaacggct ccttcttgca ccaattgctc aatccccttg tggaaggatt
    16381 tttgcttcat aacattctta gcagaaactt tcatgaaaat ttcaggagta aaggttggca
    16441 gtggttcaaa ttcaaacttg tttttaccaa ctgtcaaggt atccccaact tgataagtac
    16501 cggtatcgta aaccccgata atatcacctg ccacggcatt gatcacattc tcacgacttt
    16561 ccgccataaa ctgggtaaca ttagatagtt tggccccctt accagtacga gggagattga
    16621 cactcatgcc acgctcaaat tcgcctgata cgatacggac aaaggcaata cggtcacggt
    16681 gacgaggatc catgttggct tggattttaa agacaaagcc tgagaaatcc ttgtcataag
    16741 gatccacaat ttcaccgtct gttttcttgt gaccatgtgg ttctggagca aacttgagga
    16801 agatttcaag gaaggtctgc acaccaaagt ttgtcagggc tgaaccgaaa aagacaggcg
    16861 tcaattctcc agccagaata gcttcctctg aaaactcatt cccagcttca tttaaaagct
    16921 caatgtcatc cttgacttgc tcgtagaaag gattgctacc aaagagtttg tccccgtctt
    16981 ctagactggc aaaacgctca tcccctttgt aaagctctaa acgttggtta tagaggtcat
    17041 acaagccctc aaaggctttc cccatcccga taggccagtt catagggtag ctagcaatgc
    17101 ccaagatttc ttccaattct tgcaagagat ccaaaggctc acgaccgtca cggtccagct
    17161 tgttcataaa ggtaaaaact ggaatgccac gatgtttcac aacctcaaac aatttcttgg
    17221 tttgagcctc gatccccttg gcagagtcca cgaccatgac cgcagcatcc accgccatca
    17281 aggtacgata ggtatcttct gagaagtcct cgtgccctgg cgtgtctaag atattcacgc
    17341 gcttgccgtc gtagtcaaat tgcataacag atgaagtaac agaaatccca cgttgcttct
    17401 cgatatccat ccagtcagat ttagcaaaag tccctgtttt cttccctttt accgtaccag
    17461 cctcacgaat ctcaccccca aagtagagta actgctcagt gatggttgtt ttccccgcgt
    17521 ccgggtggga gataatggca aaggtacgac gtttcttaat ttcttcttga atattcataa
    17581 gttctctttc tttgattctc tatttttctt gtttcaatag ctgagaatga tttttacatt
    17641 ggattttacc attcctttca acattccatt atatcggatt ttagcatttt tttcaatttc
    17701 tatttctttt cacttccccc tcccttattt ataggaaaat atggtaaaat agaacagact
    17761 aaaaatcatc atttcacgaa aggatgcaag atgaaaatta cgcaagaaga ggtaacacac
    17821 gttgccaatc tttcaaaatt aagattctct gaagaagaaa ctgctgcctt tgcgaccacc
    17881 ttgtctaaga ttgttgacat ggttgaattg ctgggcgaag ttgacacaac tggtgtcgca
    17941 cctactacga ctatggctga ccgcaagact gtactccgcc ctgatgtggc cgaagaagga
    18001 acagaccgtg atcgcttgtt taaaaacgta cctgaacaag acaactacta tatcaaggtg
    18061 ccagctatcc tagacgatgg aggagatgcc taatgacttt taacaataaa actattgaag
    18121 agttgcacaa tctccttgtc tctaaggaaa tttctgcaac agaattgacc caagcaacac
    18181 ttgaaaatat caagtctcgt gaggaagccc tcaattcatt tgtcaccatc gctgaggagc
    18241 aagctcttgt tcaagctaaa gccattgatg aagctggaat tgatgctaac aatgtccttt
    18301 caggaattcc acttgctgtt aaggataaca tctctacaga cggtattctc acaactgctg
    18361 cctcaaaaat gctctacaac tatgagccaa tctttgatgc gacagctgtt gccaatgcaa
    18421 aaaccaaagg catgattgtc gttggaaaga ccaacatgga cgaatttgct atgggtggtt
    18481 ccggtgaaac ttcacactac ggagcaacta aaaacgcttg ggaccacagc aaggttcctg
    18541 gtgggtcatc aagtggttct gccgcagctg tagcctcagg acaagttcgc ttgtcacttg
    18601 gttctgatac tggtggttcc atccgccaac ctgctgcctt caacggaatc gttggtctca
    18661 aaccaaccta cggaacagtt tcacgtttcg gtctcattgc ctttggtagc tcattagacc
    18721 agattggacc ttttgctcct actgttaagg aaaatgccct cttgctcaac gctattgcca
    18781 gcgaagatac taaagactct acttctgctc ctgtccgcat cgccgacttt acttcaaaaa
    18841 tcggccaaga cattaagggc atgaaaattg ctttgcctaa ggaataccta ggcgaaggaa
    18901 ttgatccaga ggttaaggaa acaatcttaa acgcggccaa acactttgaa aaattgggtg
    18961 ctatcgtcga agaagtcagc cttcctcact ctaaatacgg tgttgccgtt tattacatca
    19021 tcgcttcatc agaagcttca tcaaacttgc aacgttttga cggtatccgt tacggctacc
    19081 gcgcagaaga tgcgactaat cttgatgaaa tctatgtaaa cagccgtagc caaggttttg
    19141 gtgaagaagt gaagcgccgt atcatgctgg gtactttcag tctttcatca ggttactacg
    19201 atgcctacta caagaaggct ggacaggtcc gtacacttat cattcaagat ttcgaaaaag
    19261 tcttcgcgga ttacgatttg attttgggtc caactgctcc aagtgttgcc tatgacttgg
    19321 attctctcaa ccatgaccca gttgccatgt acttagccga cctcttgacc atacctgtaa
    19381 acttggcagg actgcctgga atttcgattc ctgctggatt ctctcaaggt ctacctgtcg
    19441 gactccaatt gattggtccc aagtactctg aggaaaccat ttaccaagct gctgctgctt
    19501 ttgaagcaac aacagactac cacaaacaac aacccgtgat ttttggaggt gacaactaat
    19561 gaactttgaa acagtcatcg gacttgaagt ccacgtagag ctcaacacca attcaaaaat
    19621 cttctcacct acttctgccc actttggaaa tgaccaaaat gccaacacta acgtgattga
    19681 ctggtctttc ccaggagttc taccagttct caataaaggg gttgttgatg ccggtatcaa
    19741 ggctgctctt gccctcaaca tggacctcca caaaaaaatg cactttgacc gcaagaacta
    19801 cttctaccct gataatccca aagcctacca aatttctcag tttgatgagc caatcggtta
    19861 taacggctgg attgaagtcg agctagaaga cggtacgacc aagaaaattg gtatcgaacg
    19921 cgcccactta gaggaagacg ctggtaaaaa cacccacggt acagacggct actcttacgt
    19981 tgaccttaac cgccaagggg tacctttgat tgagattgta tctgaagccg atatgcgttc
    20041 gccagaggag gcctatgctt atctgacagc cctcaaggaa gttatccagt acgctggcat
    20101 ttctgacgtt aagatggaag aaggttctat gcgtgtggat gccaacatct cccttcgtcc
    20161 ttatggtcaa gagaaattcg gtaccaagac tgaattgaag aacctcaact ccttctcaaa
    20221 cgttcgtaaa ggtcttgaat acgaagtcca acgccaggct gaaattcttc gctcaggtgg
    20281 tcaaatccgc caagaaacac gccgttacga tgaagcgaat aaagcaacca tcctcatgcg
    20341 tgtcaaggaa ggggctgctg actaccgcta cttcccagaa ccagacctac ccctctttga
    20401 aatttctgac gagtggattg aggaaatgcg gactgagttg ccagagtttc caaaagaacg
    20461 tcgtgcgcgt tatgtatctg accttggttt atcagactac gatgctagtc agttgactgc
    20521 taataaagtc acttctgact tctttgaaaa agctgttgcc ctaggtggtg atgccaaaca
    20581 agtctctaac tggctccaag gggaagtcgc tcagttcttg aatgctgaag gtaaaacact
    20641 ggaacaaatc gaattgacac cagaaaactt ggttgaaatg attgccatca tcgaagacgg
    20701 tactatttca tctaagattg ccaagaaagt ctttgtccat ctagctaaaa atggcggtgg
    20761 cgcgcgtgaa tacgtggaaa aagcaggtat ggttcaaatt tcagatccag ctatcttgat
    20821 cccaatcatc caccaagtct ttgccgataa cgaagctgct gttgccgact tcaagtcagg
    20881 caaacgtaac gccgacaaag cctttacagg attccttatg aaggcaacca aaggccaagc
    20941 caacccacaa gttgccctta aactacttgc acaggaattg gcgaagttga aagaaaacta
    21001 gacagaacaa aaccagccct aaggttggtt ttttcttctc taccaactcc caataactat
    21061 tttggcttta tttccagagt attttatggt aaaatgaaga gtaataatat ttattaaaga
    21121 ggtaaaaaca tgattgaagc aagtaaatta aaagctggta tgacctttga aacagctgac
    21181 ggcaaattga ttcgcgtttt ggaagctagt caccacaagc caggtaaagg aaacacgatc
    21241 atgcgtatga aattgcgtga tgtccgtact ggttctacat ttgacacaag ctaccgtcca
    21301 gaggaaaaat ttgaacaagc tattatcgag actgtcccag ctcaatactt gtacaaaatg
    21361 gatgacacag catacttcat gaatacagaa acttacgacc agtacgaaat ccctgtagtc
    21421 aatgttgaaa acgaattgct ttacatcctt gaaaactctg atgtgaaaat ccaattctac
    21481 ggaactgaag tgatcggtgt caccgttcct actactgttg agttgacagt tgctgaaact
    21541 caaccatcta tcaaaggtgc tactgttaca ggttctggta aaccagcaac gatggaaact
    21601 ggacttgtcg taaacgttcc agacttcatc gaagcaggac aaaaactcgt tatcaacact
    21661 gcagaaggaa cttacgtttc tcgtgcctaa tctctagaaa gaggtcattc tatgggaatt
    21721 gaagaacaac ttggcgaaat cgttatcgcc ccacgtgtac ttgaaaaaat cattgctatc
    21781 gctactgcaa aggtagaggg tgttcactct ttttcaaaca gatcagtgtc tgataccctt
    21841 tcaaaacttt cactcggccg tggcgtttat cttaaaaacg tggacgaaga actcacagca
    21901 gatatctatc tctaccttga gtacggagta aaagttccta aggtagcggt tgctatccag
    21961 aaagctgtca aagatgccgt ccgtaatatg gctgatgtag aactcgctgc tatcaatatt
    22021 cacgttgcag gtatcgtccc agataaaaca ccaaaaccag aattgaaaga tctatttgac
    22081 gaggacttcc tcaatgacta gtccactatt agaatctaga cgccaactcc gtaaatgcgc
    22141 ttttcaagct ctcatgagcc ttgagttcgg tacgaatgtc gaaactgctt gtcgtttcgc
    22201 ctatactcat gatcgtgaag atacggatgt acaacttcca gcctttttga tagacctcgt
    22261 ttctggtgtt caagctaaaa aggaagaact agataagcaa atcactcagc atttaaaagt
    22321 aggttggacc attgaacgct taacgctcgt ggagagaaac ctccttcgct tgggagtttt
    22381 tgaaatcact tcatttgaca ctcctcagct ggttgctgtt aatgaagcta tcgagcttgc
    22441 aaaggacttc tccgatcaaa aatctgcccg ttttatcaat ggactgctca gccagtttgt
    22501 aacagaagaa caataaaaag aaaaagtgtt tgatagatat caaacacttt ttctttgcct
    22561 cccactatct aaaaaaatga taatagatat aattgtaaac aaaaatccag ataggttttg
    22621 catgattgag aaagttaaaa aaactatggc agagaatcgt taatctcaga ttgtcggtag
    22681 aacgataaac aagggcaaaa aagaaaccaa tcagactata atataataaa ctaattggat
    22741 ctctgtgaga tagtatcaaa tggctaatcc caaagataag gcctgataag atgacatcta
    22801 aatagtactt tgacttagga aagaaggtat tcataaaata ccctctatca agagtctcct
    22861 caaaaacagg accgatgatt acaagcagga caaaagataa gatagtcgat aaaaaggttg
    22921 gttgtccatt tgaaagaacc acggtaaaat actcatcatg aatattccta tggttaatca
    22981 aatgagcata gcgtgcctaa aaattaccga gaatctgata aaccacataa gttgcaaata
    23041 aggagaagac aaatgaccag tcccagctct ttttcttttt taacctccaa attaatagaa
    23101 aaggaaactt cccactaatc ccactgttaa aataagagaa tagacatcag ctcctaaccc
    23161 taaaatgatc gtcacataca atccaattgt ttgtggtaaa taggtagata gtaaaataat
    23221 aagcaaaaat attccaaatt gtcttagttt ctttgtgttt ctcatcgtac ttttttgaaa
    23281 gattaccctg ttcggaagcc gtacttccaa gcatctatat aagaattaag tgccccttgc
    23341 ctcatatagg gagcaaattc tctataatat aaccatctac tatatccatc ttcccaaaca
    23401 gcaagaccac ctgaagtttg ctccaagtcc tcagttgaaa gaactgtaaa tgtttctgta
    23461 cctgtcattg caagtacctt cttaaaatag attgttgtag gctcacattt atagtatatt
    23521 tctttttttg tctattttat agtctatctc ctcaactggc aatttttcga cctgaattgc
    23581 atttttccat aaaaaatgag acctttctag tctcatttag tcattcttag tattttctaa
    23641 atcgttgata gcgttcttcc agcaactctt ctagcggttt ttgtgaaagt ctagccagct
    23701 ccgtttggag ttcttttttg acactcttaa ttagttcttt actagaaagt cctacttcag
    23761 aaatcacctt atccaccacg tccatttcta acagttcatg cgaagtgatt ttcatcagtt
    23821 ctgctgcttc catggcgcga gtaccgtcct tccataaaat ggaagcaaag ccttctggac
    23881 tgagaatggc atagatagaa ttttccagca tccagacacg gtccgcgaca gctagagcca
    23941 gagccccgcc tgaaccacct tcaccgataa taatggcgat aataggaact ttcaggtcac
    24001 tcatttccat gagattgcga gcgatagctt ccccttgacc acgttcttcc gctccgacac
    24061 caggataagc acctgctgta ttgataaagg tcacaactgg acggccaaat ttctcagcct
    24121 gtttcatcaa ccgcagtgcc tttcggtagc cttctggatg tggttggcca aaattccgtt
    24181 tgaggttgtc ttgcaaactc ttgccttttt ggataccaac cactgttaca gcttggtctc
    24241 caagccaacc aataccacca acaactgcac catcatcacg aaaagaacgg tcaccatgta
    24301 attggataaa ttcatcaaaa atgcctgtcg caaagtccaa ggttgtcaag cgactctgct
    24361 cacgcgcttc tctgactatt tttgcaatat tcatctagga ctccctccat gcaatctgac
    24421 taggctagca atcgtatctg gtaagtctct tcttttgaca atagcatcca caaagccatg
    24481 ttctaatagg aattctgcct tttggaaatc ctcaggcaag ctttcacgaa ccgtattttc
    24541 aatcacacga cgcccagcaa aaccaaccaa gctctgtggt tcagccagaa tgatatcgcc
    24601 ttccatagcg aaagaagctg tcacaccacc agtcgttgga tctgtcaaaa tggtcaggta
    24661 aaagagacca gcatttgaat ggcgtttaac cgctgcagag atcttagcca tctgcatgag
    24721 actcatgatt ccttcctgca tacgggctcc accagaggct gtgaatagga caactggtaa
    24781 tttttcgaca gtcgcatact caaacaaacg agtgattttt tcacctacaa ccgtacccat
    24841 agaagccatg ataaaattag aatccataat cccaagagcc acagtctgac ctttaataag
    24901 agcagttcct gtcacaacgg cttcatgcag acctgttttt tcacgcatag atgccagttt
    24961 cttttggtaa ccagggaaat gcaagggatc cttgctttca atccctgtaa acaattcttt
    25021 gaaggttccc atatcaatcg tcaaagccaa gcgttcttgg gcagaaatac gaaaggtata
    25081 gctacagtgc ggacagatac gttcacttcc cagatccttc tgatagatgg tatgcttaca
    25141 gcctggacac tgggaaaata attcatctgg aacctctggc ttagcttgag gtttttccct
    25201 aaccgaacga ttgggattga ttcgaatata cttatctttt ttactaaata gagccattga
    25261 ttcccctttt cggtttaaac tcttaaagtc attttattct ttttcttgat atttaggtaa
    25321 gaaggtttcc atcaagaagg aagtatcata atccccagca atgacattgc gatctgaaat
    25381 gagatcaagc tggaaatctg cattggtctg cactccttca atctctaatt catagagggc
    25441 acgttgcatt ttcatcaagg cgtcaaaacg attttcgccg tgtactatga ttttggcaat
    25501 catactatca taataaggcg gaatggtata acctggataa actgctgaat ccacgcgcaa
    25561 gccaactcca ccacttggca gatagagatt agtaatctta cctggacttg gagcaaagtt
    25621 aaaggctggg ttttctgcat tgatacgaca ctcgatggca tgaccgcgta ggacaatatc
    25681 ttcttgctta acagacaaag gctgacctgc cgcaatgcaa atctgttcct taacgatatc
    25741 aacacctgaa acaaactctg ttactggatg ttctacctga acacgagtat tcatctccat
    25801 gaaatagaaa ttgctacttg cttcatcaag aagaaattca atggttcctg cattctcata
    25861 gccaacaaac tctgccgctc gaacagcagc agcacctatt tcatgacgca gcgtttttcc
    25921 gattgcaatc gagggacttt cttccaaaac cttttggtta ttcctttgaa gagaacaatc
    25981 ccgttcaccc aagtgaatca catgtccatg ctcatcacct aggatttgaa cctcaatgtg
    26041 ccgagctgga tagataaccc gttctatgta catggcacca ttgccataat tggccttggc
    26101 ctcactagag gcagtttcaa aggcagaaac gaggtcatct ggtttttcaa ccttacgaat
    26161 ccctttacca cctccacctg ctgaagcctt gagcataaca ggatagccaa ttttttcagc
    26221 aacaatcaaa gcttcttcag agttatgcac ttctccatct gaacctggta taacaggcac
    26281 acctgcttta atcatctgag cacgcgcatt gatcttatcc cccatcatat ccataacatg
    26341 accagatgga ccgataaact tgatacctac ttcttcacac atggtcgcaa atttggaatt
    26401 ttcactgaga aatccaaaac cagggtgaat agcttctgcc tcagtcaaga ctgcagctga
    26461 tagaactgca ttaatattga gataagactc tgttgccttg ccaggaccaa tacaaactgc
    26521 ttcatctgcc aacagcgtat gaagagcttc cttatcagca gttgaataaa ccgctaccgt
    26581 cgcaatcccc aattcacgtg ccgcacggat aatacgaacc gcaatttcac cacgattggc
    26641 aattaaaatt tttcgaaaca tggagaacct ccttagttcc caattgcaaa agtaagggta
    26701 ccactggctg caagcttgcc atccacttca gcctttgctt caaccacagc tatggtgcca
    26761 cgacgtttta caaaagtcgc tgtcataacc aattggtcgc ctggtacaac ttgcttcttg
    26821 aacttaacct tatccatacc agcgtaaaag accagttttc ctttattttc aggttttgat
    26881 aactccaaca caccagcagt ttgcgccaag gcttccataa tcagaacacc tggcataact
    26941 gggtattgag gaaagtggcc gttaaagaaa ggctcgttga tggtcacatt tttgatagca
    27001 acaatggtat cctcgctcac ctccaagaca cggtccacta gaagcatagg ataacggtgg
    27061 ggaagggctt ctttgattcc ttgaatatcg atcatttgat acgtaccaat cctttaccaa
    27121 actcaaccat ttcttcgtta gagacgagaa tttccgttac cacaccatcc ttaggagctg
    27181 ggatttcatt catgactttc atggcttcga taattaccaa tgtttgacct tttttgacac
    27241 tatcaccaac tgtaacgaag gcaggtttat ctggtccagc agccaagtaa accactccaa
    27301 caagtggact ctctacaaga tttccctcac tagccacact tgcttcagct ggagctggaa
    27361 cttcttctgc tacagtctct gctggagcag atgtaggagc tactggactc ggtgttgcta
    27421 gaacgggtgc tggagcgact tgagttgcaa cttcaggcac aggtctcgct tcattcttgc
    27481 taaactgcaa ctcatccgtc ccatttttat aagaaaattc tctcaaactt gactggtcaa
    27541 attgagtcat caagtcttta atatcgttta aattcatact tatctattct cccaacgttt
    27601 gaaagcaaga actgcattgt ggcctccaaa accaaaagta tttgaaatag cgtatggaat
    27661 ttctttctcc aagccttgtc cataaacgac attagcttcg atataatctg atacttcact
    27721 tgtcccagct gtcattggta caaagttatg acgcatagct tcgatggtga cgatagcttc
    27781 tactgcaccc gcagccccca gcaaatgtcc tgtaaaagac ttggttgatg atacaggtac
    27841 ttccttacca agaacagcta cgatagcacc actttctcct ttttcattgg caggagttga
    27901 cgttccgtga gcattgacat aggctacttg ctctggagaa atctcagctt cttccaaggc
    27961 tagtttgatg gccttgatag ctccctgacc ttctggatgt ggagaagtca tgtggtaggc
    28021 atcacaagta tttccgtaac caaccacttc agccaggata gtagctccac gtttttcagc
    28081 gtgttcaaga ctttctagaa ccaacatccc tgaaccttca cccataacaa acccattgcg
    28141 atccttatca aatgggatcg aagcacgagt tggatcctct gtagtagaga gagctgttaa
    28201 ggcttggaaa ccagcgatgg caaaaggtgt gatagaagct tctgttcctc ccaccaacat
    28261 cacatcttgg aaaccaaact taatggagcg gaaggcatcc ccaatcgcat catttgatga
    28321 agagcaggca gtattgatag atttacaaac accgtttgca ccaaaacgca tggctacatt
    28381 cccagaagcc atatttggta aagcttttgg aagagtcatt ggtttgacac gtttgggtcc
    28441 tttttcatga aggcgaagta cctgatcttc aatttccttg attccaccaa taccagatgc
    28501 aacgataaca ccaaaacgat ccctattaag agcctctaca tcaagattgg catgatttac
    28561 agcctcttgg gctgcataca aggcatataa agaatagtta tcaaaacggt tggtatcttt
    28621 ttttacaaag tatttatcga acggaaaatc ttggatttct gccgcattat gcacatcaaa
    28681 gtcactatga tcaaattttg taatgccacc aatgccgatt ttcccagttg ctaaactatt
    28741 ccaaaattct tctggtgtat ttccgattgg agatgttact ccataacctg ttaccactac
    28801 tcgatttagt ttcattcttt tcacctctag ctttcgctac atacttaagc caccatcaat
    28861 ggcaatcact tgaccagtta gataatcttg gcctgctaaa aatactgtca aatctgcaac
    28921 ctgctctgcc tgcccaaatt ctttcatcgg aatctgagct agtgtagctt ccttaatctt
    28981 atctgataag atagctgtca tatcagactc aatcattcct ggagcaatca cattgactcg
    29041 tatattccga ctagcgacct cgcgtgccac agacttggta aagccaatca agccagcctt
    29101 agaagcagca tagttagctt gaccaatatt ccccatcaaa ccaacaacac tagacatatt
    29161 aatgatagca ccttctctgg ctttcatcat cggtttcaag actgattgtg tcatattaaa
    29221 ggcaccagtc agattgacct tgagcacttt ttcaaaatct gcttctgtca tcttgagcat
    29281 aagagtatct tgggtaatcc ctgcattgtt gaccaaaaca tctactgaac ccagttctgc
    29341 aatagcttga tcaatcatac gcttagcgtc tgcaaaatct gatacatctc ctgaaatggg
    29401 aaccaccttg ataccatagt ttgaaaactc agcgagcaat tcttctgaga ttgccccacg
    29461 actgtttaag acaatgttgg ctcctgcttg agcaaacttg tgggcgatgg caagaccaat
    29521 tccacgactc gaacctgtaa taaagatatt tttatgttct agtttcattt ttttcctttc
    29581 aaaacttcta cttattttag tctatttttc taaaagtgct actaaactcg cttgatcttc
    29641 cacatgagct aagtgagcag tttgatcaat ttttttaaca aaacctgaca agactttccc
    29701 cggtccaatc tcgataaagt tgcttatgcc tgcttcttgc atgaccccaa tactttcata
    29761 gaaacgaacg ggttccttga cctgacgcgt caagagctga gcaatgtcct ctttttgcat
    29821 cacagcagct tctgtattgc cgactagggg acaagtaaaa tctgaaaaac ttacctgagc
    29881 tagagtttca gctagtttct ggctagcagg ctcaaggaga gcggtgtgaa agggacctga
    29941 caccttaaga ggaatcaagc gtttggcacc tgcttcttgc aaaagttcaa ccgctcgatc
    30001 aactgcaacc acttctccag caatgacgat ttgtgcaggt gtgttatagt tggctggagt
    30061 aaccactcca agttcagaag ctttttgaca ggcttcttca atgacctcta ctggcgtatt
    30121 gagaactgct accatcttgc cagagtcagc aggagccgct tcttccatat aggctccacg
    30181 cttagctacc aaggcaaccg catcttcaaa atccaaggcg ccgcttgcca ccaaggcaga
    30241 gtattctcca agagacaaac cagcaaccat atcaggctga tagccctttt cttgcaataa
    30301 acggtagata gcaaccgaag tcgctagaat ggctggttgc gtatagcggg tctgattgag
    30361 tttgtcttct tccgtatcga tgagataacg taaatcataa ccgagcacct gactcgctcg
    30421 atcaatcgtt tctttaacaa tcggatactg atcatagaaa tcccgtccca tccctagata
    30481 ctgggcacct tgaccagcaa ataaaaaggc tgttttagtc atttcttaca actcctgccc
    30541 agcgagaggc ttcttcttga attttcttag cggctccgta atacaaatct tttaggattt
    30601 cttcagctgt ttcttcttta gaaacaagcc ctgcgatttg acctgccatg acagagccac
    30661 cctccacatc accgtgaaca actgctttgg ctagggcacc tgctcccatt tgttcaaaga
    30721 tttctaaatc aggatcttcc tgcttaaagg catctttttc agccagttca aaatctctag
    30781 tcaactgatt tttaatagca cgaacagcat gaccaaagtg ctgagctgaa atcgtagtat
    30841 caatatccct tgcttttaaa attttctctt tgtagtttgg atgggcattc gactcttttg
    30901 caactacaaa ccgtgtcccc acctgtacag cctctgcacc tagcataaag ccagccgcag
    30961 caccttcacc atccgcaatt cctcctgcag caataacagg aatagatata gctgtggcta
    31021 cctgtcgcac caaggtcatg gttgttaatt taccgatatg ccccccagct tccattcctt
    31081 ctgcaataac agcgtctgca ccgatttttt ccatgcgttt agctaaagcg acactaggaa
    31141 caacaggaat aacgattatc ccagcttcat ggaaacgttc catatacttg cttggatttc
    31201 ctgctcctgt tgtgacaact ttaacacctt cttcaataac gagatccacg atatcttcca
    31261 caaagggaga taagagcatg atgttgaccc caaagggttt atcagtcaat gatttgattt
    31321 tatcaatatt ggccttgaca acttctttcg gggcatttcc cccaccgata attcctaatc
    31381 ctccagcctt ggaaacagcc cctgccaaat caccatcagc aacccaggcc atccctcctt
    31441 ggaaaatagg atagtcaatc ttcaataatt ctgtaatacg cgttttcata gtgcctccaa
    31501 ccttccttgc ttacgtaata gttcgatttc accataattt gacagtcaaa ctattaccta
    31561 aacaagaggg agtgggtttc tccctactcc ttctactaat attctgctta ttttgcttgc
    31621 tcttcaacgt aagcaaccaa gtcaccaact gttttcaagt cattttctgc ttcgatttgg
    31681 atatcaaaag catcttcgat ttctgagatt acttggaaca agtccaatga atctgcgtcc
    31741 aaatcatcaa aagttgattc aagtgttact tctgatgcgt cttttccaag ttcttcaacg
    31801 ataatttctt gtactttttc aaatactgcc atgataggac tcctttaaaa taaatagttt
    31861 ttttataaca atgtgttcac cacatgatta cctaaattgt aagaatgagc gtgccccagg
    31921 tcaagcctcc accgaagcct gatagaagaa cagtttggct accatctaaa gggatgagac
    31981 cttgttctac acactctgaa agtaaaatcg ggatactggc tgcactggta ttgccatatt
    32041 ccatcatatt agctggaagt ttggctcggt caacaccaat ttttctagcc atcttatcca
    32101 aaatacggtt attggcttga tgaagtagca gataatccaa gtctgtcacc tctataggag
    32161 attcatcaat agtctgcttg atagacttgg ctacatctcg aatggcaaaa tcaaagactg
    32221 tgcgtccatc catcttcaaa aatgaatctg cactttcttg atctgaaaat ggagaatgca
    32281 aacctgaatg cccataagtt aaacactcgc tgcgacttcc atcgctattg agactctcag
    32341 ctaagaaatg ctcttgctcg ctagcttcta acaagacacc accagcacca tctccaaaca
    32401 acacagctgt tgatcgatcc gaccaatcga ctgccttaga gagggtttca ctaccaatca
    32461 ccaagccttt ttgaaagcga ccagaagcga taaacttttc agcagttgaa agagcaaata
    32521 caaatccact gcaagccgcg gttaagtcaa aagcaaaggc tttattagca ccaatattag
    32581 cttgaacacg agcagctgta gagggcatca tcgaatctgg agtaatggta gctaggatga
    32641 taaaatccag ttcttctcct gttattccag cttttgccat cagtttctta gcaacctctg
    32701 tagccaaatc actggtagat tctgttcttg aaatatgcct ttgtcgtatt cccgttcgac
    32761 ttgaaatcca ctcatcattg gtatccataa tctgagccaa gtcgtgattt gtaaccactt
    32821 gctctggcac ataatgagca acctgactta tttttgcaaa agccattatt tcaaatcctc
    32881 caaaaattgg taaagattag tcaaaccttt acccatgaca gcaatttctt cctcgctcat
    32941 gccatcaata attttttcta ccatggcctt gtggaagcgt ttatgcagtc tatgaatcaa
    33001 gcgacccttc tttgtcaaat gcagatgcac cacacgacga tcctgttctg accgaactcg
    33061 ctcaatgtag cccttacgct ctaaattgtt caaacttgtc gtaacagttc caagagttac
    33121 catcaactct tttgacactt gacttggagt cacatctgga gccttaccga tgacatcaat
    33181 cgtatgcatt tctttgatgg agatatcctt aaaacgacta cctctcaagt tcacttcctc
    33241 aattacaagg acattgttaa atatagatgt taaatattca ttgattcgtt ggtagtccat
    33301 ttttcatatc cctccttctt caaaaaactt ttacaatcaa aacatttgac agaaagaatt
    33361 atatcaaaat tcaaagaatg atgcaagtat tttttatttt cctgtaaatt taggtcttct
    33421 tctctccgaa tgagctcgca ctccttcttt gaaatcctct gtttgagcta aggatttctg
    33481 taggttcagt tctaaagtag cgtaaccctg ccagtcttta aattggctct cccaaaccaa
    33541 cttcttaatg gcagcatagg aattacttga agcacgtctt aattttttaa gaagctgttc
    33601 tctcgtcttt tcaagttttt cagcttcaga aacgcggtaa accaaccccc attctagggc
    33661 tttttctgcc gttaaagcct ctcctgtcat agctaattga gcagcacgcg tcacaccgat
    33721 actgcggctc aagagatgaa ttccccctgc atctggagcc aaaccaacac caacaaaggc
    33781 ttggataaac ttagccttat ccgtcgccaa acagaaatct gccgcaacag ccatattcgc
    33841 tgcggcacct gcaacagcac cgtcaacttc cattaaaaca ggtttggcta tttgcttgat
    33901 tttataagaa atcgtattga ccaactctgc gatttttgtc aatgatggaa tatcatcctc
    33961 atccactgcc cgcttcatct ctaccaaatc tcccccaact gagaagacct ttccattggc
    34021 attgattaag ataaaatgca cagctggatt ttcttctgcc aaagtcagag cttctaaaat
    34081 ctcctcacac atgggaatat gaaaaccatt tgcgacctca ggacggttca aggtaaggat
    34141 tgccaagtcc tcttcaagct gataaataat gtgttccatc agggctcctt tttattttat
    34201 aagcagttta tactcttcga aaatctcttt aaaccgcgtc agcttccatc tgcaacctca
    34261 aaacagtatt ttgagctgac ttcgtctagc ttcttagttt gctctttgat tttcattgag
    34321 tgttaaatta tttcactgtc aaagtatatc ttttttagga gcagaaagca agaaaaaatc
    34381 gactgaaagt gtctcagccg ataagaaagg ctcgctttag gctagaaagc atcttatttt
    34441 cttcattgaa aaaagccttt ctttctgcta taatcgtata aaatacttac tttaggagtt
    34501 cttatgaaag ttgttaaatt tggaggtagt tctcttgcct ctgctagtca attagaaaaa
    34561 gttttaaaca tcgtcaaaag cgattcagag cgtcgttttg tagtcgtttc tgcgcctggt
    34621 aaacgcaatg ctgaagatac taaggttacg gatgccctga ttaaatacta ccgcgactat
    34681 gttgcgggta acgatattag caagagccaa agctggatta tcgaccgcta tgctgctatg
    34741 gttagtgaat tgggactaaa accagctgtg ctagaaaaaa tttctaaaag cattcacgcc
    34801 ttggccactc ttcctattga agaaaatgaa tttctctacg atactttcct agcagccggt
    34861 gaaaataaca atgccaaatt gattgctgcc tactttaacc aaaatggtat cgatgcacgc
    34921 tatatgcacc ctagagaagc tgggattgtg gtcacaagtg aacctggtca cgctcgcatc
    34981 attccatcaa gttatgacaa gattgaagaa ttgacaaaca ccaatgaagt ccttgtcatt
    35041 cctggtttct ttggtgtcac taaggaaaat caaatctgta ctttctcacg tggaggttct
    35101 gatattacag gttctatcat tgctgctggt gtcaaagctg acctctatga aaactttacg
    35161 gacgttgatg gtatctttgc agcccaccct ggtattatcc accaaccaca ctcgattcct
    35221 gagttgacct accgtgaaat gcgcgagttg gcctatgcag gcttctcagt ccttcatgac
    35281 gaggctcttc ttcctgccta ccgtggaaaa attcctctgg ttatcaagaa taccaacaac
    35341 cctgaccatc caggtactcg tatcgttcta aaacacagta atgatgaatt tccagttgtg
    35401 ggaattgctg gtgactcagg ctttgtcagc attaacatgt cgaaatacct catgaaccgt
    35461 gaggttggat ttggccgcaa ggttctgcaa atcctggaag aacttaacat cggttgggaa
    35521 catatgccaa caggtatcga cgatctttct atcattctcc gttctcgcca actaactccc
    35581 atcaaggaag aagaaatcct gcgtcagttg gttcaaaagg ctaaagtaga tcatgcagaa
    35641 atcgaacacg acctttctat cattatgatt gttggtgaaa aaatgaagag ccatatcgga
    35701 gtgactgcta ctgcgacacg cgctctatct gaaaacaaaa tcaacatcca gatgatgtct
    35761 caaggttcta gtgaagtttc tattatgttt gttgtcaata aagaccaaga gaaagcagca
    35821 attaaagccc tctacaatgc cttttttgga gaaagtaagg aagactaagc atggcccaat
    35881 cacttaacaa aacagtactc ctcagtacga caggcacttc ctacctctct atcgctggga
    35941 aagttgggaa attccttgtc ggagatcagg ctttggaatt ttacccagat gtcaatgtcg
    36001 aacaatttat ccagattcct tggagccata tcaatcagat tggagccaat gtcactggac
    36061 gcaaaatcag ccgccacttc gaagtcttta cagacaaagg aaaattcctc tttgcttcaa
    36121 aagactcagg tgccattctc aaaattgcac gcgaaaaact aggcaatgac aaggtcgtca
    36181 aacttccgac cctgattcag acaattagcc aaaaatttaa aaatctattt gcaaaaaagt
    36241 agaaacttta gtataatcat agcaacggat aagtaggtta tcttcttctt tcagaaagtc
    36301 tgcgggtact gcgagcagat aggggggata ggtgaaattc taccgttagt aacaattaca
    36361 tacacaatca agtgcacacc tgtgaagttg gatggaaccg tggccctgcc actccaacgt
    36421 tttgtcaggc gtgctttttt cataaaggag ttcttatgtt agatatcaaa cgtattcgta
    36481 cagattttga agctgtcgca gaaaaattag ctacacgtgg tgtagatgct gctgtcttga
    36541 atgaaatgaa agaaatcgat gctaaacgtc gtaacatctt ggtcaaggtt gaaactctca
    36601 aagcagaacg taacacagtt tctgctgaga ttgcccaagc taagcgcaac aaggaaaata
    36661 cagatgacaa gattgctgcc atgcaaaatc tatctgctga ggttaaagcc ttggatgctg
    36721 aattggcaga aatcgatgct aaattgacag aatttacaac gactcttcca aatatcccag
    36781 ctgacagcgt tcctgttggg actgacgaag acgacaatgt ggaagttcgc cgttggggta
    36841 ctccacgcga gtttgacttc gaacctaaag ctcactggga tctcggtgaa gaccttggta
    36901 tccttgactg ggaacgcggt ggtaaggtaa caggcgctcg cttcctcttc tataaaggcc
    36961 tcggtgctcg tttggaacgt gctatctaca actttatgtt ggatgaacat ggaaaagaag
    37021 gctatactga agtcatcaca ccttacatag tcaaccatga ttctatgttt ggtactggtc
    37081 agtatccaaa atttaaggaa gatacttttg aactcagcga taccaacttt gtcttgattc
    37141 caactgctga agttcctctg acaaactact accgtgatga aatcttagac ggcaaagatc
    37201 ttccaatcta cttcactgcc atgagtccgt cattccgttc tgaggctggt tctgccggtc
    37261 gtgatacgcg tggcttgatc cgtttgcacc aattccacaa ggttgaaatg gtcaaatttg
    37321 ccaaaccaga agaatcttac gaagaattgg aaaaaatgac agccaacgct gaaaacattc
    37381 ttcaaaaact caaccttcca taccgtgtcg ttgctctctc tactggagat atgggcttct
    37441 cagctgcgaa gacttacgac ttggaagtgt ggattccagc acaaaacaat taccgtgaaa
    37501 tctcaagctg ttcaaacaca gaagatttcc aagcccgtcg tgcccaaatc cgttaccgtg
    37561 atgaagcaga tggcaaggtg aaactccttc ataccttgaa cggctctgga cttgcagttg
    37621 gacgtacagt ggctgcaatt cttgaaaatt accaaaatga agatggttct gtgaccatcc
    37681 cagaagcact tcgtccatac atgggtggag ctgaagtcat caaaccataa aaaataaggt
    37741 ttagctattt ctagctagac cttttttcgt aaccaaatca gataagcacc tagtacaaag
    37801 aataaaatag ttaggcatat aatggtttca gccaatacca ggtaatccag aaatggaagt
    37861 ttcaaaattc cctgagccat cttgagcgag gtcgctgtga taatggttgg gaaggtgagg
    37921 gctgagaggg ctggttgaaa accttgtttt aaaatgttgg gcagacgagt taaaacaaag
    37981 aaaaagaagg attgagaagc caaaatcatg acaatcaaga cccaagtcgg caggctggtt
    38041 cctcctactc gaactagaga agccaagagt agagagaaag gagcacagta gattccttct
    38101 tgtccaagca aggctagtgg gagtggatgt ttctttaaat cgctataaat aaggggatag
    38161 agatagaagg tcaagagaaa accaaaactc aaggtcgcat aggcaatttc gataatacct
    38221 accagaggat aggtcaaggc agccactgct atccccacat agagaaccgt ccaacttgga
    38281 gtggcatgaa ccctccgccc tgaacaagca aacttgatgg taaaaccagc aatcaaggtc
    38341 aaatccaaga gaaatgaaaa ccaccaaatc ccttgtgcta ccaaaggaag ataagagaat
    38401 acgcgaaaga cataggtcga taaaatcatc ccagccatag gaaaggttgc cattcctgac
    38461 aaaagagggg gcttggtcaa ttcttgcttg gtttctttcc aattaaagag atgcagaatt
    38521 agaaagtaaa tccataaaac caaaccagtc agactaaaaa gatgggatag aaccggcaac
    38581 gtatctaaaa taagatttcc agctcctgcc aaacctagca aacaacctga aaatactaag
    38641 gggagttttt tcatcctaac ctccaataat catgttagtt tcagtataac ataaaagcgc
    38701 ttaaatgagg atttaaaaaa acgaagtccg cttatttcag acttcatttt actcagatat
    38761 gaattaggca taaggttgca attctggatt aattggtgta ttagctaagt tgttggcata
    38821 gttacagagg attgctaggc tgacaccaaa aaccacatcc aaggcatttt gttgagtgta
    38881 gccagcttct aaaaactcag acaaggcttc atctcctaca cgacccttgg tattgataac
    38941 tgccaaggta aacttagcta gggtatccaa tttaggatct gtttcaattg gagtacgatt
    39001 gcgaagagct tgaatcaagt catcattcat ctggatttgt ttgatggaaa aggctgtgtg
    39061 acctgcgaca cagaaggcac aaccattggt cacggctgcc gtgatttgca ccacttcacg
    39121 ctcaacgggt gtcaggctgt tgcgacggtg gatagatgag acaatttggt aggcttctaa
    39181 aacagtcggg gcattggcca agagaccgat taggttggga atatagccat tgttgtcttt
    39241 ttctactgtt tcaagaattt ctttcacttc tgctggtgct gactctactg tatggatagt
    39301 aaatgttgtc ataagatacc tcttttctta ttattgacac taatattatt ggaaaatctt
    39361 ataaaatcct gattcctaag tttatctaag ataaagcttt attctctcat aagattttcg
    39421 ttgttatatt agtttatcac acttccaatc acttgcataa tatatattat atatcaggct
    39481 gataaaaatt atttataggc aaaaaaatca cacgagctgt gtgattccat tatttgtcaa
    39541 aatacttttt agtttcagca ataacgactg gcgacaagac caagagggca atcaagtttg
    39601 gcagagccat caaggcgtta acgatatctg cgataatcca gaccatatcc aactcgataa
    39661 atcctcctaa caagaccatg agcacaaaaa acacacggta gagccagata aagcgagccc
    39721 caaagaggaa ctcaaaacag cgttctccgt aatagttcca acctagaatc gttgtaaagg
    39781 caaaaagtac aaggaagatg gtcaagaggg caggcccaaa gtgtgaaaag actgttgaga
    39841 aagctgactg agtcaaggca accccattca agtcaccact ccaaactcca gttaccaaga
    39901 tggtcaaacc agttagagta caaatgatga gggtatcaat aaaggttcct gtcatggaaa
    39961 tcaaaccttg ctctactggt tcatttgtct tggcagctgc agctgcaata ggagcagaac
    40021 ccagaccaga ttcgtttgag aacacaccac gcgccacacc attttgaata gccatccgaa
    40081 cgctagcacc agcaaatcca cctaccgcag caaggggact aaaagctgag gtaaagacta
    40141 aagcgattgt gccagggatt tttccgatat taaagaaaat aactgtaaga gttcctaaga
    40201 tataaatgag ggccataaaa ggaacaacag tagttgaaac cttagaaata gacttgagtc
    40261 caccaaagac tgcaatcgct acaaagacag acaagacgag agctgtgatg gctggcgaaa
    40321 tcgtcgttgt attttggata gattctgtaa tcgagttgac ttgggtgaag gttccgattc
    40381 ccaagagagc aaccaatact cctgctactg caaacaaaac agcaagtggt cgccactttt
    40441 ctcccatccc tagaaggata tagtgcatgg gacctcccgc tactgcacca tggtcgtcct
    40501 tggtgcggta tttgatggcc aagagtcctt ccgcatactt ggtagccatt ccaaagaaag
    40561 ccgccatcca catccaaaat agagctcctg gtccaccaac cttgatagcc gtcgcaactc
    40621 ctatgatatt tcctgttcca acagttgatg ccaaggctgt acacagagct gcaaaactgg
    40681 atacatcacc atgtccctta tcctggataa aaataagctg aaaggccttg ggcagacgca
    40741 aaacctgcaa gagtcctagc cgcatggtta ggtaaatccc tgttccgacc aataaaatca
    40801 agaggggcgg tccccaagca aaagcatcga ttgatttaag caattctaac atttccttct
    40861 cctatcgttt caaccccaaa agaaagagca catgcaagat acatgtactc tggaatgctt
    40921 agataaatgc taaaaagcgg tctatcctag ctctgtcctt ttacctgaga gtttgagcag
    40981 ttgcctgcct tgccccttcg gtgcctttac ggtctctcca gagttccgtc catttacagt
    41041 catggaaaat caaacgattc cccacttcta ttaaacttca ttcggtgttg gtatttaatt
    41101 gattctaatt ttacaaaaaa tgttggcttt tgtcaatgtg tttattagta aaaattagtt
    41161 caacagtttt tactttataa agtccagaat actgctatcc tttaaaagtg acaatagtcg
    41221 caccactgcc tccagcattt tgtggggcat agccgaaact cttgacatgt ttgtttcttt
    41281 gcaagtattt ggtaactcct tcacggatga ctcctgttcc gataccatgg atgatatcaa
    41341 cttgagccat attgttaagc aaggcttggt cgatgaaggt atctagctca ttcatggctt
    41401 cttcatagcg cttgcctcga agatccagtc tagcttgagg tcctcgccca gaagttcgtt
    41461 tcacaacatt gacctgtttc ttcttgactg gtttttcttg ctgggcttga acaagatcaa
    41521 actctttctc ttccaaggtc atcttaatca agccaacttg ggcttcccag cgaccgtcct
    41581 tgagttgact ggtcaaggta ccacgctgac cataactgag aaccacgata tcatctccca
    41641 cctttggagc tcgttttttc ttggcctttt gaaggacctt atttttagac aagtccactt
    41701 tttcaggagc caattttttc aacttggcct tggcttcaat gatttcgtgg ggcttgagtt
    41761 gggatttact gtggagattt ttgagaatct ggtcactttc acttagggcc atatccacaa
    41821 tctcagcagc ctgttcacgc gccttgttaa gctcggtttc cttttcacga ttaagctcgt
    41881 tgtagagttt ttttagcgca cggttcatct tgagattttc ttgctccacc tcacggatat
    41941 tgtccaaacg tttgcggctt tccagcgtct gctcttctaa ttgctcaatg atacgattga
    42001 cgtcattgtc ctgatcgatc tgctgactgg catctcctac gataacttca gataggccta
    42061 gacgtttggc aatttcaaag gcattacttc ggccaggaac accctgcata aagcgatagg
    42121 tcgggcgaag agttgcagta tcaaactcca tactggcatt ttgcacaaag gctgtctcaa
    42181 taccgtaggc cttgagttct ggatagtggg tcgtcgccat ggtcttgatt tgacgcaggc
    42241 gaaggtcctc cagaatagcc atggcaaggg ctgctccctc ttggggatca gtaccagccc
    42301 ccaactcatc caaaagtaag agtgaatgtt ggttgacctt gccaagaata tccacgatat
    42361 tggtcatatg gctagagaag gtagacaagc tctgctcaat agactgctca tctccaatat
    42421 cagcaaagat ttcttcaaaa ataccaacac gacttccctt gtctgctaaa atcggcaatc
    42481 ctgactgggc catgacctgt gtcaagccca gagttttgag catgatggtc ttcccacctg
    42541 tattgggacc tgtaatgaca atagctgtta aatcttgacc aaaatggaca tcatttgcga
    42601 cggcattttt gaccaaagga tggcagacat ggagcagttg aatctcttga ttttctgaca
    42661 gctgaggcac gactgcttgt ctttcttgga taaatcgaac cttggcacga atcaagtcca
    42721 gatgaccgat aatccaagcg tcattagcaa tctcagccgc atgagggcgg acacgctcag
    42781 aaatttcttg gagaatgcga agcatttcat agcgctcatc tgctcgcaga ctagcaattt
    42841 cttcgctcag tttgactacc tcacgtggtt cgatatagac ggtgtttcca ctagcagaaa
    42901 tatcatgaac gacacctgca atcttattgc ggtaggtgtt tttgactggt aaaacctgac
    42961 ggccatttct gctagcaaca attccttccg tcaacatctg cgctttttgc ttgagcaagt
    43021 cttgtaaaac atcgcgtacc tgactctcgc tatcatgtat ttttcgacgg attcgcgcca
    43081 attcttcact ggcaaaattt tcaatgaaac ccgcatcatt aaaggcctga agatttcctt
    43141 gtaattgcgg aaaatcatgt aatttctcaa accaaagggc taattcttcc aagctgacat
    43201 tttccagatt ggcataaaaa ctttgaagtt ctcggctggc aagaagcacg cgtttcaaga
    43261 gtaggaactc ctcgatattg agatccgctc ccatctccaa cctcttgcag actcctgcaa
    43321 tttccttagt tgagagaata gtaaaatgcg gttgctcgac gaaaagagcc tgcatttctt
    43381 tcatctcagc aaaagcctgt ttgattttat ctgctttggc agtcggagcc agctgtctca
    43441 attgctccaa gccctgctcg gtcaacaaat gaggatcaaa caaggccttg accttatcga
    43501 actctaatgt ttctaatatt ttcttattca tctttatttc cttgtctttg aatgtctagg
    43561 tgtggtagct ttttacattc tgatagattc gagtcaaatc tgtaaacaaa gggctaggaa
    43621 aactcctgcc ctttttatcc gattaaattt gtcacccaga tttgtttgag ccaactggtt
    43681 gttatcggta tgctctggat gatgtgtttt gcgacgatac tcttttcaag aggattttgt
    43741 ataactgcca tggggatggt cgccaagatt gtcaaggcca tttgcaagac aaataaggtc
    43801 accaacatgg acaagatacc tgctgaaact tggaacaact taccacccag ttttttgcta
    43861 ggaatcaagt gtaagagaag accaagcaaa cgaccaatgc tatagaaaat cccaaataca
    43921 agcaagtagc cgatacctgc ataaaagacc ttatccagct gaaagagttg atccgatggg
    43981 aaaaagaaag tcccctgacc ttcctgcgaa tttgcataag ggagcaataa atggaattgc
    44041 tctccaagcc ccttataaaa ctggccagcc ataaaagccg atgccatggc tgaaatcagg
    44101 taataaacct gtaagagcag gcctctccga tagccgatat aaaatcccca aaccaagacc
    44161 aatagaagaa ggaatgaaat cataaggaat cctcaatctt gctctgttct tgcttacaag
    44221 tcacaagctt gtgacggagt tcttctagct cttgctcctt atcgtcaaat tcaatctcac
    44281 ggctgagctg agttgataaa cagttgactg ccaacaaaag agcgattgtt tcatcatctg
    44341 cgctaggcat ttgttcttta attgcttggt atttttctgt cgcaacctta gcgatttcct
    44401 ccataaaaag gttatcatgt tcgcttgtca aggttaacga ttttttcccg aatgtaaatt
    44461 tgaatcgatt tagatttgcc ataaaattca cctcacgata ttataccaaa attcgctaat
    44521 tttgtcagtt tttacaaatt ttactgcttt tgtggtacaa tagaaactat ggcaagtatc
    44581 acactcacac caagcgaaaa ggatattcag gcttttcttg aacactatca aaccagtctg
    44641 gctcccagta agaatcccta tatccgctac tttttgaaac tacctcaagc aacggtttct
    44701 atctatactt ctggaaaaat cttgcttcag ggtgaagggg ctgagaaata cgctagtttc
    44761 tttggctatc aacttgtaga ggaaaacagg gggcaaaatc ttcctttaat tgggacagat
    44821 gaggtgggaa atggttccta ctttggtggg cttgcagttg tggctgcctt tgtcacatct
    44881 gaccagcacg actttttacg aaaactcggt gtgggggatt ctaagactct gaccgaccaa
    44941 aagatccgtc agattgctcc tattctcaag gaaaaaatcc agcaccaggc actccttctc
    45001 tcacccagca agtacaacga ggtcatcgga gaccgctaca atgctgtttc ggttaaggtt
    45061 gccctccata atcaggctat ctatctcctc cttcaaaaag gtgttcagcc tgagaaaatt
    45121 gtgattgatg cctttaccag tgctaaaaat tatgacaagt acttggcaca agaggccaat
    45181 cgtttcagca atcctatcag cttagaagaa aaggctgagg gcaaatactt gtctgtcgca
    45241 gtttcttctg tcattgcgcg tgatctcttt ctggaaaatc ttgaaaattt gggacgagaa
    45301 ctgggttatc agctcccaag tggagctgga acggcttctg acaaggtggc tagccagatt
    45361 ttgcaagcct atggtatgca gggactcagc ttctgcgcca aattgcactt taaaaacact
    45421 gaaaaagcga aaaaacgctt agaaaggtaa gttatgaatt catttaaaaa tttcttaaaa
    45481 gagtggggat tgttcctcct aattctgtca ttactagctt taagtcgtat ctttttttgg
    45541 agcaatgttc gcgtagaagg acattccatg gatccgaccc tagcggatgg cgaaattctc
    45601 ttcgttgtaa aacaccttcc tattgaccgt tttgatatcg tggtggccca tgaggaagat
    45661 ggcaataagg acatcgtcaa gcgcgtgatt ggaatgcctg gcgacaccat tcgttacgaa
    45721 aatgataaac tctacatcaa tgacaaagaa acggacgagc cttatctagc agactatatc
    45781 aaacgcttca aggatgacaa actccaaagc acctactcag gcaagggctt tgaaggaaat
    45841 aaaggaactt tctttagaag tatcgctcaa aaagcccaag ccttcacagt tgatgtcaac
    45901 tacaacacca actttagctt tactgttcca gaaggagaat accttctcct cggagatgac
    45961 cgcttggttt cgagcgacag ccgccacgta ggtaccttca aagcaaaaga tatcacaggg
    46021 gaagctaaat tccgcttctg gccaatcacc cgtatcggaa cattttaaga gacctaagag
    46081 gccgagaatc accaatctca gcctcttctt ctatcgtgag aagtgattgt ttattgacaa
    46141 atactcaacg aaaatcaaag aacaaactag gaagctagcc gtaggctgct taaaacagtg
    46201 ttttgaggtt gtggatagaa ctgacgaagt cagctcaaaa tactgttttg aggttgcaga
    46261 tggaagctga cgtggtttga agatattttc gaagagtata aaataaaaac aatcccaact
    46321 ctcacctatt catgcaaagg aattttatgg aagtttattt ttcaggaacc attgaacgga
    46381 ttatttttga aaatcccagc aatttttatc gcatcctcct cctagaaatc gacgatacgg
    46441 acgcagagga ttttgatgat tttgaaatca ttgtcacagg aaccatggct gatgtaattg
    46501 agggcgaaga ctatactttt tgggggcaaa ttgtccagca ctccaagtat ggagaacaac
    46561 tgcaaatcag tcgttatgat cgcgcaaaac caactagtaa gggcttggtc aagtactttt
    46621 caagtagcca tttcaagggg attggtctca agacagctca gaaaatcgtg gatacctatg
    46681 gcgaaaatac cattgacgaa attttgcaac acccagaaaa gttagaaggc atcgcaggac
    46741 tctctgccaa aaatcgcgag gctttcgtct ccactctccg tctcaactac ggaacggaga
    46801 tggttttgtc caaactagcc aactacggca ttcccaacaa actagccttt cagattcaag
    46861 acttttacaa ggaagaaacc cttgatgtgg ttgaaaatta tccctaccag ctggttgagg
    46921 atatcaaggg tttgggcttt accattgctg accaactagc tgaggaacta ggcatcgaaa
    46981 gtcaggctcc tgaacgcttc cgcgccggtc tagttcacag tctttttcag gcctgtatgg
    47041 aaacagggga cacctatgtt gaagcacggg atttgctgga acaaaccctt actctccttg
    47101 agtcttcccg tcccgtggaa ctagacccca gccaagttgc ccaagagctc tcctacctga
    47161 tcgaagaaga caaggttcag cagattgata ccaagatctt tgacaacagc ctctttttcg
    47221 ctgaggaagg catccgcagt cacttggttc gtatccttga aaaaggaaaa cagaagagtc
    47281 atgatttaga aaccattcaa aaacatatca ctactatcga ggaagagctg ggaattgagt
    47341 atgataacat tcaaaaacag gctatctgtg atgctatcca gaataaggtc tttatcctga
    47401 caggtgggcc tggtactggt aagacaactg ttatcaatgg aatcatcgct gtttatgccc
    47461 tgttagaggg acttgacttc aggaagaaaa gcaatctgcc tattcttctt gctgctccaa
    47521 ctggtcgagc tgctcgtcgc atgaatgaat tgacaggttt gcctagcgcg accatacatc
    47581 gccacttggg aatgacaggt gacgatgata ccagtcatct ggaagattac ctagatgctg
    47641 actttatcat cgtggatgaa ttctctatgg tagatacttg gctggccaat caactcttct
    47701 ccaatatctc ttctaacagt aagatcctca tcgtaggtga cagtgatcag ctaccttctg
    47761 tcagtcctgg acaggttcta gcggatctgc ttcatattcc tttgattcct cagactcact
    47821 tggaaaaaat ttatcgacaa agcaaagaat caaccatcgt caccctagct agtcagattc
    47881 gacagggcat cttgccagct gatttcaccc aaaaaaaagc tgaccgttcc tactttgaaa
    47941 ttgctagtgg ccatattcct gccaccattg aaaaaatctt aggtgccgcc ctcagaaatg
    48001 gtattcctgc ccgtgatatc caagttctgg ctcctatgta ccgagggacg gcagggattg
    48061 atgctatcaa tcagctcatg caagacctgc tcaatccccc acaaaaagat caactcagtt
    48121 ttgaagctcc tcagtgccac tatcgtaagg gagacaaggt cattcatttg gttaacgatg
    48181 ctgaaatcaa tgtctttaat ggggatttag gagctatcac agacctgatt cctggtaaat
    48241 acaccgaatc gaaacaagac gagattgtca ttgattttga tggtaatgaa gtctcttacc
    48301 cccgtaacga atggtacaag attcgcttgg cctatgccat gagtattcat aagtctcagg
    48361 gaagtgagtt cccagttgtc atcctaccga ttactagtgc tagccgacgt atgctggagc
    48421 gaaatctcat ctacacagcc attacacgtg ccaaaagcaa actcatctta ctaggcgaat
    48481 tacaagcctt cgactatgct acccaacaca tcggaactgc ccgaaaaacc tatctgattg
    48541 aacgcttcag tgatctactg gagaatgttg aagaaaagca acaagctgtc tctgaaacag
    48601 tcacatcaag tgcctctgaa caatcctaca tcctaaccga agaaaactgg gacagcattc
    48661 cagccatgat tgggattaca gacacagacc tcaaagagat ttttggaaaa tagtgcatca
    48721 gaaaaaccac caattcaggt gggttttctg tttattaaga ttattttact gttgctgtgc
    48781 ttgtaatcaa ttcaacagct tttttgatag tgatatcatg tttcaacatg tcagctgaaa
    48841 gcaagttttg aacttgtgca acttccatgt tgtagtctgc tgccaattgc tcaacttctt
    48901 tttggatttc ttcttctgaa gcatcaaatc cttcagcttt ggcaactgct tcgataacaa
    48961 ggttagtctt agtacgtgac tcagcttctg cttggtattg gttgtgaagg tcttcttgag
    49021 tagttccagt aatttggaag tacatgtcag ggttgatccc ttgacgttgc aagttcccaa
    49081 ggaattcatt tactgaacgg tgaacttctt cgtggatcat ttcttctgga agttctacga
    49141 tttcagcatt ttctacagct gtatcaattg ctgcaccttc aactgcatct ttgtaagctt
    49201 cttctttagc agcagccaat tctttgcggt atttttcttt caagtcagca agtgtttcaa
    49261 cttcttcatc aatgtctttt gcaagttcat cgtcaagagc tggaacttct ttagctttta
    49321 cttcgtggat agttgtcacg aatttagctt ctttacctgc aaggtcttct gcttggtagt
    49381 cttctgggaa tgttacgata acatcaacgg tttcgccagc tgagtgacct accaattggt
    49441 cttcgaaacc agggatgaat tgacctgaac caagtccaag tgagaagttt tcaccttttc
    49501 caccgtcaaa ttcaacaccg tcgatagaac caacgaagtc gatcacaaca gtgtcgccgt
    49561 cttcagcagc agcttccttg ataaccaatt cagccaggtt gttgcgttca cgttcgatac
    49621 gctcttcgac atcagcgtca gttacttctt tttctacatc aactgatact tcaaggtttt
    49681 tgtagtcacc caattttact tcaggttttg taacaacttc agcagcgata acccagtctt
    49741 gacctttttc cattgaagtt acgtcaattt ttggttgggc aaccacttca agaccagcct
    49801 cttttacagc tgcttcataa gcgtttggca aaagagcgtt cataacgtct tggtaaagtg
    49861 attcttcacc aaatttttta tcgaagatag gacgtggaag gtgaccttta cggaaacctg
    49921 gaacattaag agatttcttc actgacttga agacacggtc caattctggt ttgatttggt
    49981 cttgagagat agtgaaagtc aagacaccac ggtttgtttc tttgttttca aatgatacag
    50041 acattctgtc atttctcctt aaaatttttt aaatacagtc tattataaca ttttctataa
    50101 ataaaatcta gactaatgca gacaattata gacaacaagc ctttttccta actaaaacac
    50161 tcataaagta tagacaattt tagactactt tggatatctt ttggttagtc attttccaaa
    50221 actaatttat ctaattttta agttatattt gacttcatct tctcagtaac atgagtataa
    50281 acacttaaaa tctttgtttc attagtataa tctacacgat ccattatcgc tgttataggt
    50341 acttccaatt cagcaagcaa acttatatgc gaatatctaa aaacatgagc agtcaataca
    50401 aaatcatctt tcttaatttc acttttccta aacctgtttt tcaaaaagta attgaaacaa
    50461 gttatcatta agggagaacc attatttgta aatatataat caccttcttc taaaagaaga
    50521 tattctttta aaatttctaa cactctatca ctaataccaa ttactctata tgaagctaaa
    50581 cttttcggac tatccaaaaa cacttcgtta ttggacgatt acattatagt aaaacgaaat
    50641 aagaacagga caaatcgatc aggacagtca aatcaatttc taacaatgtt ttagaagtag
    50701 aggtgtacta ttatagtttc aatctactat acaagacgaa attgaagaaa tctttccatt
    50761 ataaaacgca tattatcaag gtttttaaac acctaataat atgcgttttt tcctatttta
    50821 aagactttta tccacctatt atacaaagtt aagtatccat cacagtttac aattagcctt
    50881 cattacctaa cccattcacc atccttcaag agagtaacct ttaagaaccg aataaataaa
    50941 tggcaaattt cgttcattta atttaactgc actgttaatt tgattagctc catctcctaa
    51001 agtatgcact cctactacac ggtgactagc atcataaact gtagatccac tagacccctc
    51061 taaagtatca acttggtaat ccaagaacat gccatcatca cttaaaactt gttttttatc
    51121 tgtatacatt tgatgaactt taaaattata tgatggatag cctgtgatag tcacagttat
    51181 tcctgtcaaa tttttttgac tagtaggaag acccaaagtc cctaattttg caccaatggg
    51241 ctcttctaga attaataaag ccaagtcata ttcccttgca tccttagaat ttaaatttct
    51301 aaattccttc aaataacgaa cttcctttac tttgatcttt ccaaatggtt cttgacttgg
    51361 actaacagtc ggaagaacat aaatatcatc cgcttctttc ccatagtcat gtctgtagta
    51421 gttgtgagcc gctgtaatta acacattatc tttaataaaa ttcgcacttc ccctcccttc
    51481 tacattcatt ccatcggcta ctccataata cttagataaa accatagctg aagtcgaata
    51541 cggatactgt aaagtattat caattttaat caaatcatca ttaccgataa tacttctgat
    51601 tgcttttggt agtatgaacc atatgttggt gaaatctcag ataatgaaga atcattagat
    51661 cctggacctt tttctagtgt ctcacttacc tcatattctt cacccgtact agaaataaca
    51721 ctcaaagcag atactgtcga taactggcta gccaataaag tactcgcaat aattgaaata
    51781 cccaattttt tataaacagt tttcttcatt attgtatcct cctaatgtaa ttatagcgta
    51841 ctattctaaa tttcttaatc tactatagaa tcaagaaatc taccaccttc tttaaatacc
    51901 ctccattatc acataaacag gtaaactttt caattaatga ctgcgctttt caatcacgct
    51961 agaggtactt acttgcttct ttgatactaa gttcagccat tctttccttg tttttctcaa
    52021 taaagcatgt tacccaagtg ggattcgttt tggagtagtc tcgcagagtc cagccaatgg
    52081 ctttattgat aaaaaattct gtttggttca agttatgaag tagaatcttt tccattaatt
    52141 gagtattggt cttctctttt cttaacaact ggtggtcaat agcgacacgt ctcagccaga
    52201 tattatctga taggctccat tttatactca atgaaaatca aagagcaaac taggaagcta
    52261 tctgcaacct caaaacactg ttttgaggtt gcagatagag ctgacgtggt ttgaagagat
    52321 tttcgaagag tattaagatt atttcttcta gttcagggtg ttcatacacc aaactcccta
    52381 ctactcgatc taggatatct accgtgtccc accaggattt tgtcacgact aactgctcta
    52441 gcttaggcaa atcggtttcc tttagataag actgcattgc tttcaaatag ttagcagcca
    52501 catattggta ttttctaggc tccttttccc agcaagtgtc tgcaaaatcc caatcgataa
    52561 tctttgtttt tttcgcttct ggtaaatatt tttatagagt ttatttcttt caggcaccgc
    52621 aatacctaga aaagaaaatt gatggcgcat ataggcttcc atgggccttg cttttttaga
    52681 gtcttttgct gcttctagct cctcaagtaa atctgctaaa ctcatctaaa actcctcttg
    52741 ccccaccaaa tggtgctgaa aggcatagac agccgcctgg gtacgatcgc tgacttcaag
    52801 tttggcaaga atattggaca cgtgggtctt gaccgtcttg agagagataa agaggtcatc
    52861 tgcgatgcgc tgattttcgt agcccttggc gatgagttgg agaacatctc gctcacgcgc
    52921 agtcaattct tcatgaagtt ccatatgatt gcggtggtat tcaaccttct tgctaacctc
    52981 ttgctcaatg gccagctcgc cagcagctac cttactgacg gcatgaagca attcatctgc
    53041 actagaagtc ttgagcatat agcctttggc accagcatct aagactggca tgattttttc
    53101 attgtccaaa taagaggtca caatcaaaat cttggcttca ggccattctt taaggattgc
    53161 taaggtcgcg tcaatcccat tcatctcagg catgacaata tccatgacaa tgacatctgg
    53221 acgcagttcc aaggccaagt caatcccttg agacccgttg gacgcctcac ccacaacttc
    53281 tacatcgtct tggaggtcaa agtagctttt caagcccaaa cggaccattt catggtcatc
    53341 tactagtaaa attttcatct ttactccttt atcattcctt atctaacagg ggaatacgga
    53401 tatcaactgc cagcccttgc ttgggagctg ttaataactg aaccgtccct gccatatctt
    53461 caacccgctc cttgatattt cgcagtccat aactcaagtc gtctaagctt cctaaccgga
    53521 aaccaatccc attgtccacc accttcagtt gcaattcaac atctgtctga tagaggtaga
    53581 catctaggca agatgcctgg gcatggcgga gggtattgct aatcaactct tgcaggatac
    53641 ggaagatatg ctcctcgatt ttcttaggca atttcgtcat attctgcttg agactaaccc
    53701 taagatcact cttgtcctca agctctttta agagaatctg aatcccttct atcaagctct
    53761 tctgctccag ttcaactggt cgcaaatgca agagcaaaac ccgcaaatcc ttctgggcag
    53821 tttctaaaat agctgtgaca ctctgcaact gggtctgcat cttttctcta tccaatttca
    53881 aagcctgctg actgataccc gataaaataa tgtgggccgc aaacaactcc tgactgactg
    53941 tatcgtgcaa atcccgagca attcgcttcc gttccttctc gataatttcc tcttcctgat
    54001 caaggctatg attttcagct ttttgaagag cctctgtcaa aaggttaagt ttacctgata
    54061 aggacttgaa actggcatcc aaatctggat ctacaacctg aactacttct tgccctgcca
    54121 ataaacgctt gagattagcc tgcatttttc ttagagaaag ctcttcgatc cctcgccaaa
    54181 acagggctaa gagacaggtc atggacatgc tgaaaaccaa caataaaaag acaaattttt
    54241 ctgttttttc gacatcgtac aaaaagatag accagtcaaa atcaagtatt tccagcaagc
    54301 tgtgggagaa aaaaaagaca aataggaagg aggtgagagc aataatgaca taggcttgtt
    54361 ttttcatcct ctaaccacct ccacatcacc aatcatagtg gtcaagaaaa tcttgacact
    54421 cttgttactc ttgagatagt cttttgtttc ttgatgatag tgttcattgc ggagggctcg
    54481 cttgggctgg ttgaaaaaag tcaaatcccc atagagacag ttaacgctga gactgacttc
    54541 cacatctaca ggtacgatga ttttggtcgt tcctaccatc tttctgagga taatgacatt
    54601 gtcatgattg gttaagatga ctctctccag atgaatagtg tccttgccca tgaagcgaaa
    54661 gagattgata tcatcaaatt ggcaagtctg gtagcttgaa aaatgatgaa gatttccaaa
    54721 ccaacgattt ttctccttct taaccgtcac aacctcttca aaaaccaaat tggtctgctc
    54781 tttttcctgg ttcatcatcg ggtaaagaag aaagagacta tagataaccg caacaaaaat
    54841 agctagaatc acaaaaggat tgagcataac gatgaaaaag aagagaatgg ttgccgctac
    54901 taaaagaaga ttattcccct ctttaccagt atagtagcga atcaaaagca aaaagaggaa
    54961 tagtatcagc agaaaacgcg aaaaatgctc tgataccatc aaaatcagag ctcctgtcag
    55021 aagacaggct tcgataaata aaaagatttt aaattttctc ataggttcat cctctccctt
    55081 ctattttatc acaattcaaa aaagtcacct cagtctgagg atggaaaaaa aggcgctggt
    55141 tacgcctttt tcatctgatc ctttgcttct tttaattttc cataaagaag atagtctact
    55201 ttttgtagat ctgctatggt ggcacagtta agggaacaca taatcaagcg tagatctgct
    55261 ttccagcctt ggacaatgcc aatcacttct tcaactgtgt aggtttcaac caattccaga
    55321 acggttcgtg acaatcccac agccttagca ccaaaaacca agcacttaat catatccagc
    55381 ggattccgaa cccctccact aaccaagagt tcgaccttat ctttccattc ttgggcattg
    55441 agaagggcct gcatggtaga ctgaccccat tgattgaggt aatcacgctg gccactacga
    55501 cggttttcga tataggcaaa gctggtgcca ccacgacccg ataggtccac tgtacgaaca
    55561 ccgaattcat aggctctttc gattgtcttg gcatccattc caaagcccac ttccttgagg
    55621 acaataggaa cgggaatttg cttgctataa tctgctagat gcgattgcca gcttctaaac
    55681 ttcctttctc cctcgggcat gagtaattcc tgcatgacat tgacatgcac ttgcaataga
    55741 acaggattca tctcttctac agtctgaagt cctaactcga caggtttgtc caatccaata
    55801 ttggttccaa ggaggagatt gggatgacta gacttgacag aaaaagaatc atccgttgga
    55861 tttttgaggg ctgcgctata agaacccgtt acaaataaaa taccacagga ttccgccacc
    55921 tgagccagct tttgattgat ttctcttccc ttattacttc caccagtcat ggcattgata
    55981 taaaaaggaa agtcccactt tcgaccagca aactctgtcg aaagatcgat ttcatccaga
    56041 ttgtaaagag gcaaggaaga atgaatcagc tccacctcat caaagctatt ataggaactt
    56101 ttctgctcaa gggcatagag gatatgctcg tccttacgat ttgtcgtcat gtcctatcct
    56161 ttcttgatat aagagctcaa tccccagatc ggcccaacga ttttttaagg ttttggttga
    56221 ttgcgcatca aaactcaggg cgatgccaca gtcaccacca ccagcaccac tactcttggc
    56281 aacggcctgc aaatcttgac tggcttcttt caactgtcta agcaaaggcg tgtaaatatc
    56341 tgtactcaag ccttctaaaa gcttgctggc tacttctact tgctcgataa tcttttctga
    56401 tttcccctgt tccaaggctt cgaccaaaga aaccaccgtt tcttttgagg aacttaaaaa
    56461 attttgattg atattttgct tgatttgctg gaccatgtga ctcgatacag ccacttcctt
    56521 ggtccatccc actaagaaat cacattctaa agttggtttc acttgtgaaa ttgaaaagcc
    56581 ccaatcacgc tccagaactg tcgccaagtt ttcttcttct aaccaagcag ccaccttctg
    56641 gcgatcaaat gactggtaga gaaccaaatc ctctgccaca atacaggcaa ggtcgcccat
    56701 ggaaccattg tctcctcgct tgagcaagac agcgctagtc agcttgaaca agagctcctg
    56761 atcaacagaa acatcataca gagccagtaa agccttgaca accaagacaa cgacgctgcc
    56821 actagaacct agaccaaact ttttcccttc tcgttccatt ttgccacaga tttctaggga
    56881 aaaagatctt aaattctgac cgcgaacagc gaggaagtct cccatcaaag caatcgtttc
    56941 ttgaatcaag ctgtagtcag gattgggcgt taagtccact gcgaaatcaa acatatctga
    57001 atagatacgg tagctgtcag aaaaagcaat ctcagccctc atatagatgg gaatatcctt
    57061 tatcaaagct aactgccctg gctctaaaat agcatattca cctgcccaat agagttttcc
    57121 gcaagtttta acagcaatca tcttgactca aatcctttgt ttttgacaca atcaagcgat
    57181 aacgctgacc gaaaatttct gacaaatgct ccaagtcttt ctcctgacaa aagaccttaa
    57241 cattgggacc agcatccatg gtaaagtagc aggcctctcc tttctcacga agctggcgaa
    57301 caaagtccat agcctcataa gaggcatccg tcagataaga aaaggctgga ctagcagtct
    57361 ttgtcgtagc atgcatagcc agggcatttt tctccgttaa ttctccaatc ttggcaaaat
    57421 cattttcctt gagataaatc agcatatcct gatagtcctt ctcagactga cgaacccagt
    57481 cgtcaaaagt cgtcgaggtt tccacacaaa gtttcatccc gtcacggcta gagattggtt
    57541 ttttcttgtc ctctagcacc aacataatca tagctagttt caagtctgtc tctacagagt
    57601 aaatttctcc actatcctta tcccaggctc ctagcggtcc ataaaaactc cgagaagaag
    57661 agcctgaggc aaacttggct tcctgcgcta actgacttct atccaatcca agcttgaaat
    57721 aagcattaca agccttgacc agggcggaca aaccactaga acttgaggac aggcccgctg
    57781 cagtaggcat attgttttga gtatcgatac ggacaaagcc ctcaccagct ggacgataac
    57841 ggtcaataat cttactcatc ttggcatgct cgacctcatt ttgtagctga ccattgatgt
    57901 aaaattcgtc agctattaca ttggctggta aaggcgacaa ggtcgtctct gtatacatat
    57961 tttccaaagt tagagaaata ctgctagtag caggcaccat ctctttttct tttttctttc
    58021 cccaatattt gataatagca atatttgcgt aggaacgtac tgtcacaggc tctctatcca
    58081 tgtctgaaca gctcctttct cttctaatct ttctgctagt tcttgtgcgt gtgtcaaatt
    58141 ggttaccaag gctatgatac aacctcctag cccaccaccg ctcatcttgg cacccagagc
    58201 accatggcta agagtcgttt caaccaaaaa gtctgcctca gggctactga ctccaatttc
    58261 ttttaaatgt aaatgcgctt gactgaggat ttgtcccagt ccttcagcat ctttttgtga
    58321 aatcgcaact tctgcttgct gggttaattc tcccaaggca tgcaaaaacg gtagggcatc
    58381 cttgccctta ttttgaacca cttggatggc ttcacgagta tgaccataaa cacccgtatc
    58441 ggcaatcacc aaataggcgg ataaatccat ctcaagttct gtaaatccta cgttcttgat
    58501 aaagcgaata ggttggtcac tgagacaggt cttagcatcc aaaccactag gattcatatg
    58561 ggcaatcatc tcagctcgat tgaccaagat ttctagtaca tcatgaggca gatcagcctg
    58621 atagtagtca aataccgcac gaatggccgc tatgctgata gccgctgacg aacccatccc
    58681 ccgtttctca gggatagccg agtcaatctc acaacgaatg caggcttctg tgatatccaa
    58741 atactccagt gaggcataaa ccgccatgga caaggtatcc tcctcataaa ggcgccaagg
    58801 actctctgca ggaactacct tacaggtcac ctccacctcc aaaagaggca gggaaatggc
    58861 aggataaccg taaacgaccg catgttcccc tattaaaatt atcttactat gtgcctgacc
    58921 gacaccaact ttttttgtca ttttttcctt ttactagacg aaaaaacgtc ttatttttca
    58981 tacaagtatt aattctttcc tatctatttt attatatttt cacaaaaaaa gcgattgttt
    59041 ccattcacaa tcgcttcttt cattattgaa cccattcgcc attatagttg acagaatagc
    59101 catctacggt cgtattcact gccaaggcac ctgagctata agcgtagtac catctgccat
    59161 tgacctggaa ccaacctgtc gtcatagaac gacgaaagaa actccatacc gttaagtaaa
    59221 gaggaaagtc gtgagggatc atgcgccatt gacaacctgt tttagtgacg tacaaagtct
    59281 cattaacaag tactcgtttc ggccatttat aggtgcggtg tttggagaaa tagggttcaa
    59341 tcttagccca ttcttgatcg tttaaatcag tatcatatgc tttgcgtgtc ataactctag
    59401 tttaacattt tttgtgaata caagttctaa ataatcgacc acgaaaattt cttaagtgga
    59461 aaacgcctta tgaagtatgc tacgggaaac ttatgcactt aatttgacaa ttcaagatgt
    59521 aaaaatatat actatagtag attgaaacta gaatagtaca cctctacttc taaaacattt
    59581 ttagaaatcg atttgactgt cctgatcgat ttgtcctgtt attattttat tttactataa
    59641 tatttgacaa gttatcctaa aagtattatt atgttgttgt gttatagatt gattgaatct
    59701 aactaaagga tcctattcaa ttactagaac tatcacatac tcaaggtcag ctcacagatg
    59761 agcaactatt ttggttacaa tgtctactaa atttaagtca aacaaataat ttagtcaaaa
    59821 ttaaaaaaat agaggaacat aaatatgatt acaaaacaga atgtaatagt gttctacgat
    59881 ttttactaga taaaactgta aattctgaag gaaggatcac ttcttcaaca gaatttggaa
    59941 atttcgtaag taatttatca ttccaacacg gaatagctgg actactgttt cctctaaata
    60001 aattgtaccc cccagaactg gattctaaaa tactctctat catcaagaag gcagtgacaa
    60061 ttagaacgac acacatatga atatcaatac tcactgctat ttggtgatgc aggctatcta
    60121 tggttactcc tacatttatt ttctatcagt aaaaatcaat actatctaca attagcaaac
    60181 gtcaccgcta agaaattaat agagaattat gatactctag aagaaataga ctttgcattg
    60241 ggaaaatctg gtgtcctatt atcattaata aaatactatc aatttaccaa tgacaatact
    60301 cttaaaactt tcatccacaa tagtatatgg ggaaatttat cattatttcc tacaaagaga
    60361 tacagccaaa gaaagcattt tagactatag ctttgctcat ggatattgtg aaattgcata
    60421 tgctttattt gcctattcta aagtcttaga accttctatg ttctataatg atctccatac
    60481 attccatgct gaattaaaaa aattattaga aaaagttact tctaatactg aaaatttagg
    60541 aaatttacaa ctttcttggt gcgaaggaat ttccggaata atcttatatc tttgtatgta
    60601 cgattgtgac ggaaacaaag atattattag taaatatcaa gaatttgttt ttaaccatca
    60661 tctaaaaatg atgacaggat attgccacgg aataactagc ttactacaaa ccactgtcta
    60721 caatcaaaac aaattactga tgaaaaaaat ccaacaggta attttagcat gttctgaacg
    60781 agatgatcac ggtttactga tgtttcaagg agatagtggt aaagcagatt tgtttgactt
    60841 cggaatagga agcagggggt atattggtgt ctattaaata ataaattccc attcgatgtg
    60901 caaacataag gagaaatgta tgaaattatt ttggacaaac aacatatata gacagttgct
    60961 gctaaacagc tgtttttcat cattcggcga cagtattttc tacctcgcca ttatcaatta
    61021 tgtggctcag tacaatttcg ctccgctagc gattttactg atttccattt cagagatggt
    61081 tcccctacta tcgcaactct ttctcgggat tctaggagat tttcaagaaa atagagtcaa
    61141 acacgcactc tgtattgcca aaatcaaaat cctgctctac gctattttga cagtatttct
    61201 cgtcttgtcg cccttttcat tagtttcagt cattatgatt gtcatcatca acctcatctc
    61261 tgacaccttg agctacctgt ctgcctacat gatgaacgcc ctctacatca gtgtaattaa
    61321 ggatgacctg catgatgcca tggggttcag gcagtctctg atgagggttg tccacattgt
    61381 cgccaatctg gctggcgcat tccttatcaa tgttataagt attcaaacta tttcccttat
    61441 caacactctg acttttgtca ttgccttttt gggcctgtat gttattcgac ataccttgta
    61501 tgaggttgaa aaaaggattg aaatgtcaca tacagcactg agttttaaga aatattttca
    61561 acatcttaaa cagtcgctgg ctgtgctcct gaggttaaaa gataccgtca tactactgtt
    61621 tctgacgacc agtatgattg ccatcttgga tgtgtcccct cggctgattg ccctccgctt
    61681 catccaacag acactagcac aactgagcat tgggcaactc ttcgccctgc tctccatcat
    61741 catgtcttgt ggagctatcc ttggcaatat gaccagcagt aatctattta aaaatatccg
    61801 tttcacgcac ctcttggttt tctgtgagat ttccctattg gctctaataa ctagtatcct
    61861 ttgtcaagcc tatatcgtaa ttttcgtgac cagtttcatc agttctacga ttatcggcat
    61921 tctcagccct cgcctacaag cagctgtctt tgcccatatc cccagtgaca agatggggac
    61981 ggtgggctct gctctgagca cagtagacat tctcgccccg tccctgctct ccctattagc
    62041 cctatccata gcatcgggcg tttcggtgca gttagcattg atatttttgt atcttatttt
    62101 gattgctctt atcttttgtc aatggttagt caagttcaac actcataact aacgaaaaag
    62161 catgtgtaga tttcacatgc ttttaatctc cccaatcgtc aggtcaagta caacaaagtc
    62221 acttctttga ttaagcgagt gttctaatat aattataagc gccctgtcat taccgaaccc
    62281 attcgccatt atagttgaca gaatagccat ctacggtcgt attcactgcc aaagcacctg
    62341 agctataagc atagtaccag ttgccattga cctggaacca acctgtcttc atgtctccat
    62401 tacctgcatt taggtagtac caagttgaac catcttgata ccaaccagtt gccatagctc
    62461 ctgatgaacg gagatagtac catttgttcc caaggttttg ccaacctgtt ttcatatcgc
    62521 catttggctg gtctaaataa taccaagtgg taccttcctg ataccagcca gtggccattg
    62581 ctcctgagga acggaggtag taccatggag caggtttgct tctatcaatg tcaatagtaa
    62641 catgaaaatc ttgagtccaa cccttagcaa cttcaccaat tggtagtgga ttgtaagaat
    62701 catcaccaaa atttcctagc ttatttaaat aataccaatt gccgtcttca taaatccagc
    62761 ctgtctttac agcataatta ttatcaaaat aataagttct cttttcagca gatagaggat
    62821 attgttcacc gtatactttt cctgtatttt cagacgtttt tgcctctagt acttgtttat
    62881 ctgtttgttc tagcaaagca ccatcttgtc caaaatagta ccacttctcc tgaaggccaa
    62941 tttcgaagac tggacgatta tcaaataaat catcacgata acctgttcca ggaatttcta
    63001 agtattgcca accgacaacc atctctccaa tatcaccaaa atagtaagtt ttaccgtcta
    63061 ttttatgcca atagattgct ttatgatcat cttttacata atattttcta ttatccttat
    63121 caacaaatcg gccacctgtg gtattcgcaa ataccgtatt tgtagctagc aaaccaaaga
    63181 aaaagactgc tagtagaact tgcatcattt ttttcaaaag tttcatttat atatcctcct
    63241 aaaacgattg tagcaaagac acgactgcat gtcaatatat aaaaactcct caaaaaagca
    63301 gttacacaac tgcaactgct tttctattct tgcatggtgt aaccaacacc acgcacggtt
    63361 ttaatgtagc ttttttgtcc tttaacatca agcttgctcc gtagatagcg gatatagaca
    63421 tctacgatat ttgtctcggt cgcactttca tacttccaaa cactttccaa caattgctca
    63481 cgagtcaata ctttcttgct tcccataagt gtcgccaaaa ggtcatactc acggcgggtc
    63541 agagcaatca tctcttcacc acgataaacc gtgtgatgtt caacatctat cctaagattg
    63601 cggtaggtcc ttggaacttt catcagactg cagtgttgat caatgaagtc ccgacctcgg
    63661 aagatcgccg aaatacgcgc taccagattt tcgataaaga ctggcttata gatgtatgaa
    63721 actgcaaaac gctgaacaac ttccagctct tcttgcaagt cttcccaatg atctaaaatc
    63781 atgatgactg aggcaggttt agttcgactc aatttttctg caaaatcctg agccatcata
    63841 tctcccagat taacgttcaa taaaatcaaa tcatagtctg tctgaagagc catggaaagg
    63901 gctttttgcc cctcctctac cagatcaacc cgatactgct ctttctggag ttccaaactt
    63961 aaaaaatgag ctagatttcg ttctttctca agtaataaaa tccgtttccc catggctgac
    64021 ctacttattt ttcgtcatac caagagtagt ggaaggttcc ttctttgtct ttacgttggt
    64081 aagtgtgagc accaaagtag tcacgttgtg cttggatcaa gttagccgga aggtcagctg
    64141 aacggtagct atcaaagtaa gtaatagctg ctgagaaagt tggcactggc acaccagctt
    64201 gaaccgcaag agctacgata tcacgcactg cttgttgata cttagcagta acatccaaga
    64261 agtactcgtc caaaagaagg ttggcaagat ctgcatcgcg gttgtaagca tctgtaatct
    64321 tttgcaagaa acgagaacgg atgatacagc catcacgcca gatagatgcg atatctgcaa
    64381 atggcaagtt ccagttgttt tctttagagg ctacacgcaa ttgagcaaat ccttgtgcgt
    64441 atgaaatgat ttttgagaag taaagggctt gacggatttt ttcaatcaat tcagccttgt
    64501 ctccttcaaa gttgaaggca gctggttttg gaagcacctt gctagcatgt acacgttctt
    64561 ctttgtaagt tgaaatgtag cgtgcaaaca ctgactcagt aatcagtgac aatggtacac
    64621 caaggtcaag agatgattgg ctcgtccatt taccagttcc cttgttacct gcagcatcaa
    64681 ggatgtagtc tacgattggt ccatcttggt cttcatcgtc tttacggctc aagatatcag
    64741 ctgtgatttc gatcaagtag ctatccaatt cacccttgtt ccactcagta aagatttcag
    64801 ccatatcctc tgcagaaagg cctagcaagt gttgcatcaa gtcatagctt tctgcgatca
    64861 attgcatatc accgtactcg ataccgttgt gaaccatttt cacatagtga ccagctccat
    64921 caggaccgat ataagtcaca catggtttgc catcttctgg tgctttagct gagatttctt
    64981 caagaacatc cgaaaccaat tcgtaggcct ctttttgtcc accaggcatg atagaaggac
    65041 cttcaagggc acctttttca ccaccagaaa ctccagtacc gataaagttg atacctgagt
    65101 ttgccaattc ttcattacga cggatggtat ctttgtagaa agtgtttcct ccgtcaatca
    65161 agatatcacc tttgtcaagg tgtggaagaa gggcttggat agtagcatct gtaccaggtc
    65221 cagcttgaac catcagcatg atacgacgag gtttttcgat tgagtttaca aaactttcaa
    65281 cgtcatagct tggtacaaaa ttcttttcag gatggcaagc aatcacatct tccgtttttt
    65341 ctttactacg gttgtagata gcaactgtgt aaccacgtga ttcaatatta agggcaaggt
    65401 tacgacccat tacggccata cctacgacac caaagttagc ttttgtcatt tgacactcct
    65461 cttgtttcat ttgttttatt ttatcatttt tacttttgaa aagaaagaat tttgtaacga
    65521 ctgcttagta gtccaagtca tccgcatgac cagcgccatt tccgacaaag tagcctgtct
    65581 tacagttaag ggtaaagaga taggttccat ctggcttata gaggttgtaa taaccattgc
    65641 cgttaacgat attgacacgt tcaaggatat attggtctcc agtgatatag ccacgtgaac
    65701 gtgaagttgc tagaatttgt tccaaaacac catccgcaaa atcccaggca gagttattac
    65761 tatcatcaat agcagactga ttataggcaa cacgactggc acttctttga acagcaaccc
    65821 ctgcactcga gagacccata ttgacttcac tgcgactact tctagtctca tttgaactac
    65881 ttggttttgg ctcactagtc gtatttgaac ttgcttgact tgaacttgag ctgctagttt
    65941 gacttgaact tgagctagaa gtacttgttt gctggctctt accaagactg atagccttat
    66001 ctagcacttt atcaagctcc gtatttccag ttttaatatc cgtaaattta gcatccgatt
    66061 tggctttggc attggtatcc aacacaccat ccacaatagc tggtttttca aattgtgcat
    66121 tgacatcttg aatggccttg atttgcgtta ctagactatc atatttagat ttggcaagcg
    66181 tatgttcacg actaccttcc agcttatcaa gtaaagtctt gagttgactc agtttatcaa
    66241 actggctatt tttcaaagcc gttttattgc tatttgtgta aaaggcgtca taaagtgtat
    66301 taaaatcatc cacatccgat tgattggctg tagttgattg agaagtttca atttccttgg
    66361 tcgaacgagc cacttgacga tagacataat aagcactgac acaaataatt actgatacaa
    66421 gcgccaaaac ggtcaaaata aagccttttt tacttttctt ttctgagtcc tcttgatcca
    66481 gacgagaaag gttttgctcc tcttccactt cttcagtcat ttctgttgga ttttcatcat
    66541 ctagcaatag aggatccaag ccttgctcct catcgtccag aggcaagggt agtaagatgt
    66601 cttcagaaga tggaacttcc tccgaagaag cttctgactt ctctacagcc tcacgcatct
    66661 cttgaattaa atcatccaga ctctgagttt caacgaactc ctcttttttg tattgacgag
    66721 tcgcaaactt atccgcctca atttcatctc tgtgttgctt aacatacttg tccaaaatgg
    66781 aatcctcagg caagactcct gcttccactt cttcattttt acgaatagct tgaccaactg
    66841 ttagctcttt tgcttcatca aaatcaaatt gcggttcttg accttctttt ttatgacgat
    66901 ttcgtctttt tttactcatg agtatccctt tctattttac ctcttgccgt ttgacacgct
    66961 gaccaaaata ttgatataga tccactttca aggttccgtt gtataactta cgcttcttat
    67021 ctgcttggct accatacttg ctttcaaaag cttcatcact agtcaggata aatttgctcc
    67081 aagttttcag cggtgcaaat acttgcccca tctcagcata gagcttggtc actcctgcat
    67141 catctgacaa acgttcacca taaggcggat tggaaatgat tactccattg attttatcgg
    67201 aacgtaaatc ctgcacgcgc atctgcttaa aagtaatatc tcctgcaaca ccagctgcct
    67261 gagcattggc cttagcaatt tccaccatgc gagcatcaat atcacagccc atgatatcca
    67321 actcaagctt acgttctact tttttagccg cttctgtgcg cacttcttga atcaagcgat
    67381 cgctgatcca gttccattcc tcaaatgcaa aagagcgacg aagacctggc gccatctttc
    67441 tagcaatcat aactgcctca atacagaaag tccccgaacc acaggtcgga tcaatcaaag
    67501 gcttgtctgg ataccagtta gaaagttgta aaatggctgc tgccatattt tccttgatag
    67561 gagcgccacc tttttcggta cgataaccac gtttaaagag gctagacccg gtcgtatcaa
    67621 tcatgacagt tgccacatct ttgagaatag agacctcaat cttaaactct gggccattct
    67681 ccatcagagg aaccccttct gggcgagcat agtgtttctg caatttcttg acaacagctt
    67741 tcttagaaat agcctgaaca ctgggctcat tgtgaagttt ggacttaaca catttagctt
    67801 ttgaaatcgg taaccgagct ccaagtggta aataattttc ccaatctaaa gcgaaaactc
    67861 cctgaaatag ctcttcaaaa gtcttagctg ggaacgttcc tacgataatt ttgatacgat
    67921 ctgctgcccg aagccaaagg ttggtttcga taatagctct cacgtctcct tgaaaacgaa
    67981 cacgtccatt ttcaacctga caatcgtagc ccaactctcg cacttcacga ccaacgacag
    68041 cctcaagccc tgctgccaca gttgcaatta aattaaattc ttttttcatg ttacagtctt
    68101 gcaagacctt tctatatgtc cactttaaaa aatgaggttg agaaaatttc tcagccccaa
    68161 cctatatgca attttctata agccatgttt tgttccagaa gtgactagga ccacttcctt
    68221 cgataatcat ctgtctacca ctaacagctc tagctgatag cagtcagaat actacgttcg
    68281 tttccgcata ctccatgccc cgaccaaaat ttgggttgct agcttgaggg gtttaccgcg
    68341 ttccactctc tctgtttcca gaaagactcc gtcactgtgg cactttcaag cctactctgg
    68401 cctatccaag gacttagcca tttcaactgc cgtaacgatt tctcgtccct aggcttatgg
    68461 tttcgcctag cacaaacact acaggcatca cagcctgtgc tagcatggac tttcctcatg
    68521 agaagcaatt ctcctcacgc gattatccaa aaattgcaca tctcaaataa ctacttaaaa
    68581 atctgagtta tctaaaattt gtttaccaaa aacttctttt tccaatctat tcaggcgttt
    68641 caaaatatca aaattcgtca tagaacttgt aattgccgct tcaaggggtt ctgcttgaac
    68701 tggtgaaggt ttcggtttac gagttaattc ttccttcaaa tccgcaattt cctgacgaag
    68761 tgacttgacc aaggcagcat aggtttcata gtccttgatg acatcgtcta aaaactcgtc
    68821 aacttctact ttattatagc cacggacttc acgtccaaac tcttgttcaa aaatatcttt
    68881 cgctgaaaaa ataatacttg ccatgtctct ctccattctc gcttgctagt attattatat
    68941 aaaaaaaggc aaacaaaaat caaggtcaaa gcttcaattt tcggaaaaat tttcagcaag
    69001 ttcatttaat tgatcaaatg ttaatctctt tataaaatag tcctcttgat ttttcatctt
    69061 ttggtaaaaa taagctagtt ttgtttcatt ttcttcatca taaaaaagat aggaactagt
    69121 cgtgttttcc agcaaaaact gctggtaatc tcttaactgc cccttgtgtt catagcgagg
    69181 ataagcatat ttgacaaagt ctacctgctt aaagcgactc agtttcatct gattgccttc
    69241 attccaattt tccccatggg tttcaaaagc aaaaatggtg gccaactgga aaccgtattc
    69301 ggttttcatc tcctgagcaa cctctaaaac ccaatattca aaacccaaac tccctgtaaa
    69361 cacaagccaa gacaccccat ctgctgccat agcctctaaa tctttacgta tcgctttttt
    69421 aatcaattta agacgaggat ccttatcaga aaataaaccc aaatcaaaag cagaatagcc
    69481 taaaaccaaa gctgtagcca tttttaaccc tttctgtgca aattatggta taataaagtg
    69541 atgttattgt accaataagg agaattatga tcaactatcc acataaagtt tcatcacaaa
    69601 aaagacaaac atctctttct caacccaaaa atttcgcaaa tcgaggaatg tcttttgaaa
    69661 agatgatcaa tgctaccaac gactactatt tgtctcaggg cttggctgtt atacataaga
    69721 aaccaactcc tattcaaatc gtacaagtgg actatccaca acgaagtcgt gccaagattg
    69781 ttgaagccta ttttcgacaa gcttcaacga cggactattc tggcgtttat aatggatatt
    69841 acatcgactt tgaagtcaag gaaacaaaac aaaaacgtgc gattccgatg aaaaattttc
    69901 atccacatca gattcagcat atggaacaag tccttgccca acaaggaatc tgctttgtcc
    69961 ttcttcactt ttcttctcag caagaaacct acttattgcc ggcattcgat ttgattcgct
    70021 tctatcatca agataaggga caaaaatcaa tgccacttga atatattcga gaatatggat
    70081 atgaaatcaa ggctggtgcc ttccctcaaa ttccttatct caatgttatc aaagaacatt
    70141 tattaggtgg taaaacaaga tgaacaaacc aacgattctg cgcctaatca agtatctgag
    70201 cattagcttc ttaagcttgg ttatcgcagc cattgtctta ggcggaggag tttttttcta
    70261 ctacgttagc aaggctccta gcctatccga gagtaaacta gttgcaacaa cttctagtaa
    70321 aatctacgac aataaaaatc aactcattgc tgacttgggt tctgaacgcc gcgtcaatgc
    70381 ccaagctaat gatattccca cagatttggt taaagcaatc gtttctatcg aagaccatcg
    70441 cttcttcgac cacaggggga ttgataccat ccgtatcctg ggagctttct tgcgcaatct
    70501 gcaaagcaat tccctccaag gtggatcaac tctcactcaa cagttgatta agttgactta
    70561 cttttcaact tcgacttccg accagactat ttctcgtaag gctcaggaag cttggttagc
    70621 gattcagtta gaacaaaaag caaccaagca agaaatcttg acctactata taaataaggt
    70681 ctacatgtct aatgggaact atggaatgca gacagcagct caaaactact atggtaaaga
    70741 cctcaataat ttaagtttac ctcagttagc cttgctggct ggaatgcctc aggcaccaaa
    70801 ccaatatgac ccctattcac atccagaagc agcccaagac cgccgaaact tggtcttatc
    70861 tgaaatgaaa aatcaaggct acatctctgc tgaacagtat gagaaagcag tcaatacacc
    70921 aattactgat ggactacaaa gtctcaaatc agcaagtaat taccctgctt acatggataa
    70981 ttacctcaag gaagtcatca atcaagttga agaagaaaca ggctataacc tgctcacaac
    71041 tgggatggat gtctacacaa atgtagacca agaagctcaa aaacatctgt gggatattta
    71101 caatacagac gaatacgttg cctatccaga cgatgaattg caagtcgctt ctaccattgt
    71161 tgatgtttct aacggtaaag tcattgccca gctaggagca cgccatcagt caagtaatgt
    71221 ttccttcgga attaaccaag cagtagaaac aaaccgcgac tggggatcaa ctatgaaacc
    71281 gatcacagac tatgctcctg ccttggagta cggtatctac gattcaactg ctactatcgt
    71341 tcacgatgag ccctataact accctgggac aaatacccct gtttataact gggatagggg
    71401 ctactttggc aacatcacct tgcaatacgc cctgcaacaa tcgcgaaacg tcccagccgt
    71461 ggaaactcta aacaaggtcg gactcaaccg cgccaagact ttcctaaatg gtctcggaat
    71521 cgactaccca agtattcact actcaaatgc catttcaagt aacacaaccg aatcagacaa
    71581 aaaatatgga gcaagtagtg aaaagatggc tgctgcttac gctgcctttg caaatggtgg
    71641 aacttactat aaaccaatgt atatccataa agtcgtcttt agtgatggga gtgaaaaaga
    71701 gttctctaat gtcggaactc gtgccatgaa ggaaacgaca gcctatatga tgaccgacat
    71761 gatgaaaaca gtcttgactt atggaactgg acgaaatgcc tatcttgctt ggctccctca
    71821 ggctggtaaa acaggaacct ctaactatac agacgaggaa attgaaaacc acatcaagac
    71881 ctctcaattt gtagcacctg atgaactatt tgctggctat acgcgtaaat attcaatggc
    71941 tgtatggaca ggctattcta accgtctgac accacttgta ggcaatggcc ttacggtcgc
    72001 tgccaaagtt taccgctcta tgatgaccta cctgtctgaa ggaagcaatc cagaggattg
    72061 gaatatacca gaggggctct acagaaatgg agaattcgta tttaaaaatg gtgctcgttc
    72121 tacgtggagc tcacctgctc cacaacaacc cccatcaact gaaagttcaa gctcatcatc
    72181 agatagttca acttcacagt ctagctcaac cactccaagc acaaataata gtacgactac
    72241 caatcctaac aataatacgc aacaatcaaa tacaacccct gatcaacaaa atcagaatcc
    72301 tcaaccagca caaccataac atttatcacc cagatttttc tgggtgattt tgtcatagca
    72361 ctattgtatt tatgtgctta acaaaagcct gagaagatgt cttctcaggc tttttctgta
    72421 ctataaacct cattggaaaa gatagagact gcttccgtaa tcttgttaag aggttttact
    72481 aaatactagt ctttcttcgt ttttactaca aagagagcag atagggctag actaacactt
    72541 gctaggaaga gggctgtgtc agattgactc tcacctgttg ctggcaagat ttgttcaggt
    72601 gtttctggtc tagctatttc ttgcttataa tctggcgtct taccttgatc ggaaactaaa
    72661 gagctaagtt taaactcagg tttctctaca gttggagcat ctggtttcgt agcagaatct
    72721 tttaattggt tgagataatc tgcaaagtat tccaccattc tttccgtcaa gagatggtta
    72781 tccgtcgcat atttcatgct tgcctgaacg ctagctactt cctcttgatt gtctttgtct
    72841 gttaatttct gagctttagc caaagctgct tcatagcctg acaagtcaag aggtgtttct
    72901 gctacctgtg gacgagtaaa gatgagttcc gctgcagatt ggtatttatc gccaccatct
    72961 ccgtaagtct tagtacctgt aaggacaatt ttcttagcct taattgtctt accaaaatca
    73021 atgtcttttg gcttattgtt atctggccaa tcagttgcag taaaggtatg ctccttgcca
    73081 gactcatctg tcacaacaag tttcacatca cgcaagttac catttgaacc tgatccacgt
    73141 ggaacgtaac gaagtccagt gatttcagtt ggttctttca agaccatggt tgcaggcttg
    73201 cctacatctc caccattcca agatgtatgc cataaactag ataagtttcc atcaaaggca
    73261 tttgcaagac cttcttgagc ctgagcagga gctgtaagac ttgcaaagtc atctgctacc
    73321 aaagccgttt tcttctgaac caaagcattc ttcaaggctt caatcttggc aatctctgca
    73381 cgcgcttctt ccacactgat atcatcatcg gcctgactaa ggttaaagac cgcctctttc
    73441 aaagcatcca tagactcttt ggtgtagtta gtcatggcaa ccgttggcaa gtagttcttc
    73501 agagcatttt ctgtcaacat cttacctgtt agggtaattt cttcgatttg aagattatcc
    73561 atcatgaagt cgttataacc acggaagttg gcatttccac cagaatcacc acgagtatta
    73621 cttgcattgc cagttgagta gatacctacc caagtatccc ctgtttctgc acctgtcaca
    73681 aggaaggttg ccttcttggc tttcttagaa tctgtccaag tatttggcaa ttcatgcatt
    73741 tccaagttgc ttgcttgagt gccacgacga cctgactgga attctccctt accgactaca
    73801 aaagcatagg tattgtctga acctgcttcg tattcaaagg ttacacggta ggtcttacct
    73861 gcttcaaaac ggaagttttg tgggatggtt tggtaaacca agttacgacg gctcactagt
    73921 ccatttgtct tgagtgacca atttccttcg ataacatcat cgactttctt accgttccaa
    73981 ccacgttgtg tatatggatc gtgtttttca gacaagtgag tgcggttgtc ttcgacacct
    74041 tcgacaccac ccactacaaa tgggaagatt ccttgagcta cattttcaaa gtcttgcttg
    74101 aaggttcctt gacctgtatc gtgcttgtct ccatacatgc ttgaattgtt ttcaaaggta
    74161 cgaatttcat caaagtaagt tgcttgatca ccagcttcac gactcaatgt cagagtaaca
    74221 tttgagacgt ccgatcctgt tgtaaagaag gcgtacatgt tttggaagta acttgtatcg
    74281 ttaactgtag cattgttacg acgtgtattg tgggcgtagg cttttacata gttgagggcg
    74341 agagacttat tggtataagt agtcacttct ttttcaccag tattcacagt gatacttgcc
    74401 ttggcattac tacggttatc gacaccgaca taaacggcat acttggtatt tggtttcaag
    74461 ccagttaatt tctgagtgag actaactttt tctttgtttc cttgaatacg aagcatatcg
    74521 tttgcccctt gagacttgac aatttctgcc ttagaagcat cgcctgaaat ggtccaatgt
    74581 ttcaaggtac cactgttaaa tccttggtca tagatgtgca tgccttcact ccatgacatt
    74641 tcaggattgg tttgttttga acgatagaga acgtatggtt gatttgctag aagatctagg
    74701 gtaattttac catcttttac agttagttct tgctcttctg tcttaccttg gtcagttagc
    74761 ttgtaaaggt aaaccttgct ctttgcccaa tcgcttggaa gggtccaagt tgttgcaccg
    74821 gcctgcgtat tgaagtagta catcttttcc ttatcagtag aaagtttctt accatttgca
    74881 tcccagttcc aaggagtcaa gtaagctgaa ccatcttgga tgacacgtcc gttgagagtt
    74941 actgtacgtt cgcgatattg tggactattg acatcatttg acttacgagt tacaactact
    75001 ttattattgt cagcatctac caattccact cgcatttctg gagtccattt ataggtacta
    75061 ccgttatcgg tcatagtcac cggtgtacca ttttcccatt tacttacagt gaagtgttgg
    75121 aagtacttag tcatgacgtc atgggcaaat aagttggtta catagccatt gtagtcactt
    75181 cttccctgcc agccttcaaa gtctttcatg ctgtagccac ctagcagtgg atagttggct
    75241 gcaccaccat aacttctgta gtccccaacc caagcatctt tttggtggtt acggataaag
    75301 cgggtgatgg cactgttgat acctttattg gtgtagccac cgtaggtcaa gtcagctgcc
    75361 cagtgatgga aggtagagtc gtactcacca ccatggcccc actcgatcgc aaagcgccag
    75421 ccttgtttgt taatttcttt agcaagaacg tgggtagccc aggcaccgtt atcacctgat
    75481 tgaccattac cccaaacgtc cacatagata aagtcgagac cgtcaccaag ttttttcttc
    75541 aaatcttccc aacgtgccaa acgaccatga gctaggtcat aggcagcatc aatgttgata
    75601 ccttgatcta gccagttcca accatagcta tagcttccat ctggattctt acggagaatt
    75661 ttttcattga agtatttaga ctcaggataa gtttctgaag cgttaacgtg gatacctaga
    75721 tgagctccat atttcttagc cttctcaatt agggtcttga agtcttcgac accaccgata
    75781 cgcttaccaa tatcagcata gttcaagtga ccagagtcat ggccttcgct accatatcct
    75841 ttaaggaaaa caccttgccc aagaccatct gtgtggagat tgattttctt gataccatcc
    75901 aaggtcataa ggaatggatt ttgtgcttga gaaccaaagt tcatcgcgat acggtaagct
    75961 gtgatatcct taactttttc ccaaccttga ggattgttca taatgctacg ataagcaatg
    76021 gcaccatctt gccaatcgac tttcttgtct gcattggcat cttcagtgat aacaacctta
    76081 gcacttggaa gttccttcgt gtattctggg aaaacaatgc ccttataagc tttttcccat
    76141 tgccattcag agctgtggat tcctacatag ttggcatttc cgactgtttc tttataagct
    76201 gtcaaacgag tccagtcatt cgaaccacca ccatagctat tttgagagtt actccaaaca
    76261 ccagcagcaa gcttatctgt agaaacaaat ccatacatgt aacccttggc taggtctttc
    76321 attggattgg ttacatcgat atgatcatct ccgctgacat gcgtattgtt tgacatggtt
    76381 gccccatcaa acttagcacc agtttgatca ctagaaacag agactaaagc attgccgagg
    76441 aaactaatag aagaaagtag ttttctttcg tcatcaatct tttgacctgg agtgacttga
    76501 ttgtggttga caatcttggt cacatcaaag tgcaattgat tgtccacaac ttgcaagcgt
    76561 actgtcattt ccgcattgat taagtgagca tcatcgcgaa gcttcatcaa gtactctgct
    76621 gttgtctcat tgattttctt ataagtgact tcaggggtga ttcggtggtt attgataaag
    76681 acttggttga actgttgcac ctgtcctggc aaagtatgtc cattcaagct gtattccttg
    76741 acacgaggga aggcttggtc aatcactgct ttgaggacct tagactggat cgtatcataa
    76801 gtcaccttgc tatcgtcaac aaccggacct gtttctttct gggcaggagt atcatccgct
    76861 tttacgcctt cttgattgtc tgttttaacg ctgacaactg tacggtcatt gccataagtt
    76921 cctgccttga gaaggatctt cttctcattt ttaagattat cattgaccgc cccaggcagt
    76981 gtcactgtgt caaagagatt gacatcgtta ttgctggcat tgagttgtcc atctgacttg
    77041 agagtgatag aaagacggtt tacagaaccc ggttctggtg caactacacg gttgccttta
    77101 taccatgtgc tattacctgg agttttgtat tcccagaacc agccatcctt gtcataaccg
    77161 acaaaaacat tattattggt atctttaaat ttcaggaaga caccaaagcg tgatttgccc
    77221 ttttcagaat cttctttgaa ggttaaatca acagttgcat ttccattggc atcaacggtc
    77281 aagcccttct tttcaaacag ggctggtttg cctgcgttat cattttgagc agttgagaat
    77341 agttggttgt agcggacacc tttttcttct cggatagtga ctgttccctg ttgttctttt
    77401 ttctctaccg tttgccattc aggagttacc gtcttaggtg tttcaggttt agcagctgca
    77461 ggtttatcct cttttggttt ttcttcagcc ggtttttctt tttcaagtgc taatagttct
    77521 tcttctgtct taggtccatc tgtaacttct ggagaacctt ggtcttctcc caccttaggc
    77581 gcttcaaaat cacgcccatc attctcgttt gctgttgcaa gagcagtagc taaatcagct
    77641 ggtaagttcg ccgtggaacc agactgcacg ctatctgcaa gaaccggact tgtcccaaag
    77701 aatgcagctc caatcataac agaagcaaca cctaatgaaa atttccgaat actatattta
    77761 caacgttttt caaataatcc tttattcata aacttctaaa tcctttcatt ttttagcaag
    77821 cgtttacatt tcctttttaa aaaatactcc ttcctctgaa agtgcaatgc ttaaccctga
    77881 taaataaaaa ataattgtac ttttaatata acaaataata gctgagaaag caataggaaa
    77941 caagtaaaat taacaaaaat tttctctatt ctgacaaaaa gaggctccaa cttttggggg
    78001 tcagtacatt tagaatcttt ctttacaaat gtaaaaaagg attcagcatt caagagaaat
    78061 actaaatcct ttcttatatt ttgcaacagt tatttcacat gttttgcgag atcttcttga
    78121 gcctttttat tagactcttc tttttctttc atccattttt cctgagcttt ttggtattca
    78181 tctacagtga ctgccttgtc ttgaagttcc aagtatttat acaagactgg ttcacttgta
    78241 cctttatttc ctgacaatgc aaatggtatt gtaaatggta ccatcttaga caagattggg
    78301 cgccctgtac gagatgtagt tggaataatc aaagcactat ctgtcaacca agcttgggct
    78361 gcagcgtatt tatcatagcg tttagcaaca tctgtagcct catcaccagc ctcagtgacc
    78421 aatttttcgt agtcatatag acctactttt ttagcagcta cattatcttc ccctgagtca
    78481 aaccctaaat atgttttagt actttctcct acagaaggtt tgataatatc aaggtaggtt
    78541 gatggatcgg caaagtctgg accccaaccg acattatctg ataaatccca gtcttcgcca
    78601 gcagcatttt cagcaaaata tgtaatattg tttacttcgt ctttttgtag ttgttggata
    78661 tcaataatga cattatcagc tcctaaagtt gcttccaagg attgtttcat agattggacg
    78721 cgctgaactt ttgtagttgc tgtctggtca actggcatat ccaaatgaat tgggaaagtc
    78781 acaccttctg cttgtaaggc tgatttagct ttagcaaatt cagccttggc tttttctgga
    78841 ttgtaaagac catcctgaga atctgcaaga ttaacatcct tccattcatc cccataagtg
    78901 accaatttct ctttgaccat atcgccaaag tttttaccat ctgcttgaac aaatgttggt
    78961 ggaacaaaga tattacgtaa gattttgctt gctccagttt gtccattcaa ctgagaggca
    79021 taggctgtac gatcaaaacc aaaggcaata gcctgacgga aatccttgtt taagagagcc
    79081 tttttagtcg atgccttttg ttcgtcgctg gtcttagatg tatatttata ggactgacgg
    79141 tcaatatttg taccaactag atacgtaata gagccttgtt gagtatagac aatattgtcc
    79201 ttcatactct tctcaagctc tgcgaaactt gcacttgttg gatagagacg agctgctgta
    79261 aggctaccat ctttaaagtt ttctgcaggt ttgctggtat cttgaccatc ccagaatgac
    79321 aatttaactt tgtcaacatg cacattgtcc ttatcccagt agttcggatt tttcgcaaat
    79381 tcaacagagg attttgtcac aatggatttc aacaaataag gaccgttata caagagacta
    79441 cttggatccg tcgctttggc aaaatcatcc ccttttgagt tcaaaaactc ttcattaact
    79501 ggcgcaagca cacccatggt tgtcttagaa ttccagaagc tttctggttt gttcaaagtg
    79561 tactgaactg tctgatcatc caaagcctta attcctactt gtgagaaatc tttgatttcc
    79621 ccttttacat aggcatccaa ccctttgatt gattcttgaa caaggtaaag agcatctgat
    79681 tttttatcag cagcatattt tagtcctgtt acaaagtctt gagctttgac tgccgcgtat
    79741 tcttcacctt cagaagtata ccattttgca tccttacgga tagtataagt gtaagtcaat
    79801 ccatccttgg atacagacca atcctcagcc atagacggca caaagttccc gtagcgatca
    79861 ttttctagca aaccatcaac cacgttactg gtaatatttg ctgtcgcagc cttagcagtt
    79921 gtcaaatagt tgaggttatc agggtctgtc tcataaatgt atgagaatgt cttctcacct
    79981 ttagtgcttg aacctgatcc agagcatgca gctaaagtag tcgccgccaa taatgtcacg
    80041 cccgcaaggg caagtagttt tgaacttttc atccttttct cctttaaaac tttctctcca
    80101 ttatagactc ttttcagaaa gttgtcaaca gaattttcag aatttttgaa aattattttt
    80161 caaataacat ctttgcaaaa aatatgaata tcgtaaccgc ccaataacga agtctattga
    80221 aaaatctcca gactagagaa ctcacggata gttcctaatc tggagatttc ttatttgcac
    80281 ttttcttgta caactttagt ccacggtaaa taggcctcta aaatctcttt gtttacgaga
    80341 gtttcctcgt ttggaagaca ttctagaaga taggatagat atttctcgct atttaat
//
LOCUS       DAVAZV010000003        67435 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVAZV010000003 DAVAZV010000000
VERSION     DAVAZV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67435
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.003"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(134..1882)
                     /locus_tag="VQT46_000158"
     CDS             complement(134..1882)
                     /locus_tag="VQT46_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370267.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTISRVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            complement(1884..3608)
                     /locus_tag="VQT46_000159"
     CDS             complement(1884..3608)
                     /locus_tag="VQT46_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370268.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENLPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQT46_000160"
     CDS             complement(3666..4604)
                     /gene="msrB"
                     /locus_tag="VQT46_000160"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2370269.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4746..4823)
                     /locus_tag="VQT46_000161"
                     /pseudo
     CDS             complement(4746..4823)
                     /locus_tag="VQT46_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4899..5768)
                     /locus_tag="VQT46_000162"
     CDS             complement(4899..5768)
                     /locus_tag="VQT46_000162"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET2370270.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTKGVRVEAK"
     gene            complement(5770..7056)
                     /locus_tag="VQT46_000163"
     CDS             complement(5770..7056)
                     /locus_tag="VQT46_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET2370271.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQT46_000164"
     CDS             complement(7207..7944)
                     /gene="mecA"
                     /locus_tag="VQT46_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET2370272.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8144..9178)
                     /locus_tag="VQT46_000165"
     CDS             complement(8144..9178)
                     /locus_tag="VQT46_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2370273.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9207..10640)
                     /locus_tag="VQT46_000166"
     CDS             complement(9207..10640)
                     /locus_tag="VQT46_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET2370274.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFIAKMLTKEN"
     gene            complement(10656..11642)
                     /locus_tag="VQT46_000167"
     CDS             complement(10656..11642)
                     /locus_tag="VQT46_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2370275.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQIYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11644..12747)
                     /locus_tag="VQT46_000168"
     CDS             complement(11644..12747)
                     /locus_tag="VQT46_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2370276.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDLEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQIIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12737..13582)
                     /locus_tag="VQT46_000169"
     CDS             complement(12737..13582)
                     /locus_tag="VQT46_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2370277.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLTLDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQT46_000170"
     CDS             complement(13861..15135)
                     /gene="psr"
                     /locus_tag="VQT46_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET2370278.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQT46_000171"
     CDS             complement(15132..15980)
                     /gene="pheA"
                     /locus_tag="VQT46_000171"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET2370279.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYIDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(15977..16453)
                     /locus_tag="VQT46_000172"
     CDS             complement(15977..16453)
                     /locus_tag="VQT46_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET2370280.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRHVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQT46_000173"
     CDS             complement(16446..17729)
                     /gene="aroA"
                     /locus_tag="VQT46_000173"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET2370281.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKEYTRNHTEDMLQQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIAPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSATLIVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17821..18159)
                     /locus_tag="VQT46_000174"
     CDS             complement(17821..18159)
                     /locus_tag="VQT46_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET2370282.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18170..19273)
                     /locus_tag="VQT46_000175"
     CDS             complement(18170..19273)
                     /locus_tag="VQT46_000175"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET2370283.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQT46_000176"
     CDS             complement(19283..20449)
                     /gene="aroC"
                     /locus_tag="VQT46_000176"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET2370284.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20459..21526)
                     /locus_tag="VQT46_000177"
     CDS             complement(20459..21526)
                     /locus_tag="VQT46_000177"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET2370285.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21545..22399)
                     /locus_tag="VQT46_000178"
     CDS             complement(21545..22399)
                     /locus_tag="VQT46_000178"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET2370286.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDELSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKKMPTEEIW
                     QSLTEKYQ"
     gene            complement(22389..23066)
                     /locus_tag="VQT46_000179"
     CDS             complement(22389..23066)
                     /locus_tag="VQT46_000179"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET2370287.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23063..24226)
                     /locus_tag="VQT46_000180"
     CDS             complement(23063..24226)
                     /locus_tag="VQT46_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET2370288.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQAFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDERRFIVMDVFEYF
                     KYAKRKNLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24911..26545)
                     /locus_tag="VQT46_000181"
                     /pseudo
     CDS             complement(24911..26545)
                     /locus_tag="VQT46_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26526..27275)
                     /locus_tag="VQT46_000182"
     CDS             complement(26526..27275)
                     /locus_tag="VQT46_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370289.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLTSSDLETSLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSAPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGSVEN
                     LRKDHPDQFLESIYLSLAGRKEEVADASQGH"
     gene            27454..28908
                     /locus_tag="VQT46_000183"
     CDS             27454..28908
                     /locus_tag="VQT46_000183"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET2370290.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKEQGIQPMADVVL
                     NHKAAADNREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNGFHWHWYHFT
                     GTDYDAKRSKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQT46_000184"
     CDS             complement(28998..31616)
                     /gene="alaS"
                     /locus_tag="VQT46_000184"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET2370291.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLISPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNTSQLSSKLVAIVADNAEVGAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKIVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDAVAGKL"
     gene            complement(31638..32123)
                     /locus_tag="VQT46_000185"
     CDS             complement(31638..32123)
                     /locus_tag="VQT46_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET2370292.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLLDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32398..32637)
                     /locus_tag="VQT46_000186"
     CDS             complement(32398..32637)
                     /locus_tag="VQT46_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370293.1"
                     /translation="MKMSTFFNKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILEK"
     gene            complement(32890..33960)
                     /locus_tag="VQT46_000187"
     CDS             complement(32890..33960)
                     /locus_tag="VQT46_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2370294.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNIPAKELLPEETKEDKAFYPDVETMKHLEIYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33957..34730)
                     /locus_tag="VQT46_000188"
     CDS             complement(33957..34730)
                     /locus_tag="VQT46_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370295.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34727..35533)
                     /locus_tag="VQT46_000189"
     CDS             complement(34727..35533)
                     /locus_tag="VQT46_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370296.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35514..36671)
                     /locus_tag="VQT46_000190"
     CDS             complement(35514..36671)
                     /locus_tag="VQT46_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370297.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQT46_000191"
     CDS             complement(36730..37680)
                     /gene="murB"
                     /locus_tag="VQT46_000191"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET2370298.1"
                     /translation="MSVREKMLEILEGIDIRFQEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESLSVAKMYAGGFTPCKR"
     gene            complement(37792..38544)
                     /locus_tag="VQT46_000192"
     CDS             complement(37792..38544)
                     /locus_tag="VQT46_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET2370299.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWFEKKR
                     SLEKADALAYGLGHGGLELIFLGLTSLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLTAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQT46_000193"
     CDS             complement(38554..39285)
                     /gene="budA"
                     /locus_tag="VQT46_000193"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET2370300.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFLHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39427..40698
                     /locus_tag="VQT46_000194"
     CDS             39427..40698
                     /locus_tag="VQT46_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET2370301.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40718..41533)
                     /locus_tag="VQT46_000195"
     CDS             complement(40718..41533)
                     /locus_tag="VQT46_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2370302.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQT46_000196"
     CDS             complement(41690..42343)
                     /gene="phoU"
                     /locus_tag="VQT46_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2370303.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQT46_000197"
     CDS             complement(42355..43113)
                     /gene="pstB"
                     /locus_tag="VQT46_000197"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2370304.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQT46_000198"
     CDS             complement(43126..43929)
                     /gene="pstB"
                     /locus_tag="VQT46_000198"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2370305.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQT46_000199"
     CDS             complement(43940..44824)
                     /gene="pstA"
                     /locus_tag="VQT46_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2370306.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQT46_000200"
     CDS             complement(44814..45731)
                     /gene="pstC"
                     /locus_tag="VQT46_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2370307.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQT46_000201"
     CDS             complement(45731..46609)
                     /gene="pstS"
                     /locus_tag="VQT46_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET2370308.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47183..48487)
                     /locus_tag="VQT46_000202"
     CDS             complement(47183..48487)
                     /locus_tag="VQT46_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET2370309.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48488..49261)
                     /locus_tag="VQT46_000203"
     CDS             complement(48488..49261)
                     /locus_tag="VQT46_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET2370310.1"
                     /translation="MKSKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49251..49529)
                     /locus_tag="VQT46_000204"
     CDS             complement(49251..49529)
                     /locus_tag="VQT46_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET2370311.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGKGKISLEK"
     gene            complement(49529..49930)
                     /locus_tag="VQT46_000205"
     CDS             complement(49529..49930)
                     /locus_tag="VQT46_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET2370312.1"
                     /translation="MITLFLSPSCTSCRKAKTWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50140..50757)
                     /locus_tag="VQT46_000206"
     CDS             complement(50140..50757)
                     /locus_tag="VQT46_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET2370313.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(50747..51520)
                     /locus_tag="VQT46_000207"
     CDS             complement(50747..51520)
                     /locus_tag="VQT46_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET2370314.1"
                     /translation="MKYKGYLIDLDGTIYKGKDQIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKEKPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51531..52268)
                     /locus_tag="VQT46_000208"
     CDS             complement(51531..52268)
                     /locus_tag="VQT46_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET2370315.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIVEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEESISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52273..53403)
                     /locus_tag="VQT46_000209"
     CDS             complement(52273..53403)
                     /locus_tag="VQT46_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET2370316.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53487..53876)
                     /locus_tag="VQT46_000210"
     CDS             complement(53487..53876)
                     /locus_tag="VQT46_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET2370317.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53892..54275)
                     /locus_tag="VQT46_000211"
     CDS             complement(53892..54275)
                     /locus_tag="VQT46_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET2370318.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54276..55064)
                     /locus_tag="VQT46_000212"
     CDS             complement(54276..55064)
                     /locus_tag="VQT46_000212"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET2370319.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55057..55992)
                     /locus_tag="VQT46_000213"
     CDS             complement(55057..55992)
                     /locus_tag="VQT46_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET2370320.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLSETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56122..56298)
                     /locus_tag="VQT46_000214"
     CDS             complement(56122..56298)
                     /locus_tag="VQT46_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET2370321.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56438..57145)
                     /locus_tag="VQT46_000215"
     CDS             complement(56438..57145)
                     /locus_tag="VQT46_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET2370322.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57296..58324
                     /gene="queA"
                     /locus_tag="VQT46_000216"
     CDS             57296..58324
                     /gene="queA"
                     /locus_tag="VQT46_000216"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET2370323.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIINMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(58995..59384)
                     /locus_tag="VQT46_000217"
     CDS             complement(58995..59384)
                     /locus_tag="VQT46_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2370324.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(59438..60145)
                     /locus_tag="VQT46_000218"
     CDS             complement(59438..60145)
                     /locus_tag="VQT46_000218"
                     /inference="COORDINATES: protein motif:HMM:NF019142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2370325.1"
                     /translation="MFRRNLNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGGIIVK
                     VATKPKVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGHVTE
                     QVTVDRKQATDTVIKVPAKSKVEEVLVPCATKYEADNDLSAGQEQEITLGKNGKTVTT
                     ITYDVDGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKSQE
                     VEEVGEIGKLLLLQSIL"
     gene            complement(60845..61396)
                     /locus_tag="VQT46_000219"
     CDS             complement(60845..61396)
                     /locus_tag="VQT46_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370326.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDIEITRNSIRNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQT46_000220"
     CDS             complement(61794..62618)
                     /gene="nadE"
                     /locus_tag="VQT46_000220"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET2370327.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62615..64075)
                     /locus_tag="VQT46_000221"
     CDS             complement(62615..64075)
                     /locus_tag="VQT46_000221"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET2370328.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64191..64679)
                     /locus_tag="VQT46_000222"
     CDS             complement(64191..64679)
                     /locus_tag="VQT46_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370329.1"
                     /translation="MKNRFYYYQLLDEREEQLINKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYVIYLPWVFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64669..64878)
                     /locus_tag="VQT46_000223"
     CDS             complement(64669..64878)
                     /locus_tag="VQT46_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2370330.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65268..65710)
                     /locus_tag="VQT46_000224"
                     /pseudo
     CDS             complement(65268..65710)
                     /locus_tag="VQT46_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000640911.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(66002..66808)
                     /locus_tag="VQT46_000225"
     CDS             complement(66002..66808)
                     /locus_tag="VQT46_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370331.1"
                     /translation="MILKDINFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNI
                     ISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKV
                     KTYSLGTKQKLALLLTLVTEPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILI
                     SSHKLEDIEEICERVLFLENGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGD
                     IVQEEGLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
     gene            complement(67214..>67435)
                     /locus_tag="VQT46_000226"
     CDS             complement(67214..>67435)
                     /locus_tag="VQT46_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET2370332.1"
                     /translation="QVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELLTIKVPQP
                     VQSGDMVRALKEGLINLYKEDGTSVTVRA"
BASE COUNT        20088 a        15177 c        12543 g        19627 t
ORIGIN      
        1 acctacggct agcttcctag tttgctcttt gattttcatt gagtattaca gtaaacaatt
       61 tttctagcta ttgtaacaaa aaagtcactc gaaggcaact tttttcgtcc ataaactttc
      121 aaaagagaat ggcttattca gaactaaaag ccgcagcttt ttgcatttgg taatacttac
      181 cctttctatc catgagttct tgatggttac catattcaac aatatcacca tctactaaga
      241 caagaattaa atccgcatcc tgaatggttg acaaacggtg agcaatgatg aagcttgtgc
      301 ggcccttcat gagttttgca aaggcatcct gtaccagcac ttctgtccgt gtatcaatgg
      361 aagaagttgc ctcgtctaag ataagaatct ttggaatagc cagaaagact cgggatatgg
      421 tcaagagctg agcttggccg acagagagag attctccagc attttccaac ttggtatcgt
      481 atccctgtgg caactgttgg atgaaaaagt ctgcattagc tgctttggca gcagcaatta
      541 cttgctctcg actggcttca ggattgccaa aggcaatatt atcatgaatg gtcccttgtg
      601 tgagccaggt ttcttgaagc accataccaa actgctgtct caatgatact cgtgtataat
      661 cataaatgga ttgcccatcc agcaagatat ctcccgagct aatgggataa aaacgcataa
      721 ggagattgat aagagttgat tttccagcac ctgtcggacc aacgatggct accttactac
      781 cagctggaat atcgatagac aactccttaa tcaaaatttt ttcaggatgg tagccaaaag
      841 agacatgttt aaaggaaata gctcccttaa cttggtcact ggtcaagact tccttacctg
      901 tttcagccac ttcagggcta tctaagaccc catagatacg ctctacgcaa gccagagcac
      961 tttgcaactc agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat
     1021 agttcaaaaa agtcactaaa cgaccgacgg tcaaggttga acccatcatg atacgataag
     1081 ctcctactcc agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga
     1141 ccgttgaaga ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac
     1201 gcaatctttg gataaattct gtttgagcat tgaaggactg gattatagtc tgctggctaa
     1261 gcgattcttc aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat
     1321 gataggatct cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga
     1381 ctaagagagt catgaggaga tgaatttgga gcatggctag aatactaacc aaaatcatca
     1441 aaacaccaat gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatat
     1501 ccgtggttac acgactgacc atctctccat tgccttgccg atccgcaaaa gcaatcggta
     1561 accgatggag tttatggatg attcgctctc gtaaatctct ggtataagag aagattagac
     1621 gattatagag gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca
     1681 tctggagaaa aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga
     1741 cctgcccaat cagaataggt aggtaaattg ataagccaac ttgggcaata gttcctagaa
     1801 aggctaggaa aaggaggaag ggatggtttg ctaaatctac gactaaacgt ttgagcgtct
     1861 ggtttacagt ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca
     1921 cgatagactt gactggattt catcaagtca tcgtgcttgc caacagctag caactcacct
     1981 ttttccaaga ggagaatctg gtccgccatc tggagtgtcg aagtccgttg agaaatcaag
     2041 attaagctca tatttggcag attttcgcgg atagctttca agagcttgga ctctgtaatg
     2101 gtgtccagtg ctgaggtcgc atcatctagg atgagaaacg gagcctggcg caagactgct
     2161 cgtgcgatag acagcctttg tttttgtcca cctgagaaat ttcgccctcc tgcttcaact
     2221 agagcatcca agagtccttc cttatcactg acaaaatcct tagcttgcgc aatctccaag
     2281 gcttgccaga gttcttgatc agtcacttct tgatttaaac ctaaagtcaa gttggaacga
     2341 atagttccct taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc
     2401 tccaaattaa gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga
     2461 taaagtccaa gtaagagttg caccaagctt gatttaccag aaccagtccc cccaatgata
     2521 ccaaggattt gtccttgagt catatcaaag gaaatgtctc tcagagaagg ctgggccgca
     2581 tcaggatagg taaaagtcaa ttcttggact tgtaaaaccc gaccactggt aacttgcttt
     2641 tgttctaatt ctgaatggat gttttcggga gattccgcaa agacctcctc gattctcttg
     2701 gctgagatat aggactggtt gagggaattg atcagcatgg ctagcttgac caattccacc
     2761 aaaatctgta agaggtaatt gataagagca atgagagcac cttgactgag tactcctcct
     2821 tgaattgaaa tatagccttg ccagataata acgagaagag ttccattgac aatcagatag
     2881 gtcagaggtg ttaataaact agacaagaaa cctgtctttt cttgtaatct agcataaact
     2941 tggttaaggg tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc
     3001 cgcatccctt gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga
     3061 ctactgtaga gaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca
     3121 accatgacta agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca
     3181 ccaaaaacga taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga
     3241 atctggtagg tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg
     3301 ctgtcctttg gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa
     3361 cctactgctg cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact
     3421 gcaaagataa ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa
     3481 gattggtcaa caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac
     3541 agcttgaaca agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg
     3601 tgtttcataa atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct
     3661 ctgttttatt tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc
     3721 ttggccacaa agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc
     3781 ggtccatctg tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt
     3841 cgctccattc catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg
     3901 ctaaaacttg gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca
     3961 cctgtcgtaa tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat
     4021 ggagcctctg tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc
     4081 aacacctctt gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg
     4141 gtcacatcga tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct
     4201 tcagccagaa tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg
     4261 cgttcctgct cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa
     4321 atcccagttc gatattggcg accacggtca ttcccttgtt gattgataga tagaggatcg
     4381 ataactcgga aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc
     4441 acttggaccg tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact
     4501 tgaccattag cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc
     4561 tctaggcccc aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta
     4621 tcacgttttt aactaatact cttcgaaaat ctcttcaaac cacgtcagcg tcaccttacc
     4681 gtaggtatgt tactgacttc gtcagttcta tctgcaacct caaaacagtg tcttgagctg
     4741 acttcgtcag ttctatctgc aacctcaaaa cagtgttttg agcagcctgc ggctagcttc
     4801 ctagtttgct ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac
     4861 cctctggtca agagtttccc catcctatct tctattcttt attttgcttc tacacggaca
     4921 cctttggtat caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct
     4981 gccttaattg ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca
     5041 gaaaggtagg ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct
     5101 cttaccaagt cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg
     5161 gtcaccatgt ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca
     5221 acagcttcct tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat
     5281 tcatagtttg gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag
     5341 acttgccctt caacagaact tgcaataacg agattaccat aaatggctgg agccacattg
     5401 tcaggatgcc cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt
     5461 tgacccagtt ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa
     5521 ccgcgcgcca aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca
     5581 atttgcaaag cgattttaag caagagatta cgctcgtcat gtggaatcca tttgccaatc
     5641 tggtgttcaa tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt
     5701 acagctacac cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata
     5761 atcttcatct tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt
     5821 cttcaattca gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac
     5881 gacacgcgcc ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg
     5941 agcattgaag atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga
     6001 gaaatagtag tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc
     6061 gttgaagtct ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc
     6121 tacaacactt gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc
     6181 aataccgata gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg
     6241 cgctttaggt aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat
     6301 agaaccaacc aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt
     6361 gatattgcgg attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa
     6421 ttggctcaaa ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc
     6481 gctttctgca aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc
     6541 ttccaccatc ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt
     6601 aattttatca gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac
     6661 tgctgcttcg tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc
     6721 atggacagct aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg
     6781 agtgataaag gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc
     6841 ctggtctgat aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag
     6901 caagcgattt ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg
     6961 tgctgattga ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac
     7021 ggtaccaaat cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa
     7081 tatagccatt ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta
     7141 taaaaagaaa aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag
     7201 aaaagattag ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc
     7261 atactcttgt aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc
     7321 caacagccaa gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata
     7381 atagcgctcg ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc
     7441 aaaagctacc aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt
     7501 cttactctca gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc
     7561 aagagattga atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt
     7621 tttgataaat tcatctggag acatttgagc caattcttcc atatctggca aatccgataa
     7681 gtcttcaaaa tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc
     7741 aggttttgga gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc
     7801 tagctcatcc aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc
     7861 agcaatctcc attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt
     7921 atcactaatt tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat
     7981 actagatttt tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg
     8041 gtctttctat aggagactcc aagagaaaat ttctgcagac agatagaaaa agccttcaaa
     8101 atcggctaag agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg
     8161 ctacaccgag gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct
     8221 tataacgagt cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg
     8281 atacatcctg taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt
     8341 tatctaggat agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg
     8401 acaaaacatc tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact
     8461 gagaaaaatc acctactcta ttgattgttg gattaaagag ataaactaac acatttccca
     8521 tcacaaccaa aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca
     8581 catttaagcc aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca
     8641 gtttttcaat tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt
     8701 ttttctctaa caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg
     8761 catcgtcaat catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt
     8821 tcaaggttgt ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta
     8881 catcattgaa aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac
     8941 tataaccacc aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt
     9001 tatagataag ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg
     9061 ctttaattgt aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg
     9121 cttttcgctt tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga
     9181 tttttttctc ctttgtttag tagatactag ttttcctttg taagcatttt tgctataaat
     9241 ataatcacaa gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa
     9301 aagctgcttc ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg
     9361 attgtccttg agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa
     9421 ctaagcagaa agactccaat cataccatag tcggtataca actccatgat ataactactt
     9481 ccgataccat gccctttcag gtattccttg ttcaagacaa gataggatag attgtgggca
     9541 taactattac tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct
     9601 ccgaaaatgg ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa
     9661 ttacggaaat ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca
     9721 aaactagtcc cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa
     9781 acttggacat tatcccgtac ataattgagt actcccatcg ctaacatgag aataggagaa
     9841 cctacaaaaa tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc
     9901 cgcataaagt aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca
     9961 attgccaaat gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat
    10021 ttctttggct tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg
    10081 taggtaaaat aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc
    10141 aaacgataca agagccgttc aaataaccga atgaaataga aaggataagt tagaagaaaa
    10201 actcctagtg atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata
    10261 tttgctactt ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc
    10321 aagcccagaa tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag
    10381 gtatccaaag caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa
    10441 atggttaaat agaaaataaa atggattaag taatacttga tatcattcca acaagcaatt
    10501 aagctactaa ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac
    10561 agatacacaa ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat
    10621 aatcgtttcc catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca
    10681 atatttttca gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta
    10741 attcttctcc ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa
    10801 aaacgatgaa tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta
    10861 tccagaataa agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga
    10921 tagtttttca caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc
    10981 tctgcatagg gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta
    11041 gtattaacca catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg
    11101 taaatcaacc ccttaggaaa ggatagggca gttgcaatct gtctcttgat tagcttattg
    11161 caaatcgtcc caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca
    11221 cagacaaaat agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc
    11281 atgacaccac agcttgaaac atccgcatct tcttgaacta attgctcata taagctctga
    11341 atcatttctg gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc
    11401 tgcttcatcc catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac
    11461 accctgtcat cttgttcagc gattgagtca cacaagcgac cactttcatc tgttgcacca
    11521 tcatcaacaa gaataatttc cagattttga tagatctgct tctgaatgga agctatcgat
    11581 ttttctaggt actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc
    11641 atgctactcc tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg
    11701 aatgaattgg ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat
    11761 cgcctgagct gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa
    11821 ttcctcagcc cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac
    11881 atacactcca ggaaaacctt cttgtttaga catagacaag agaactttcg tctgagataa
    11941 atactgataa ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc
    12001 tttgactcgt tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata
    12061 gttttttccc tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt
    12121 ttcctcaatc cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc
    12181 ttgagatttt tctagaatag tctgaaaatc atatccattg tagattatct gtaatttaga
    12241 agcataatct ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat
    12301 tgtattcgca gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag
    12361 ttcttcaata cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa
    12421 cagtggtgga ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa
    12481 acgacgagtc agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct
    12541 ggtttggcga taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata
    12601 tcccttgtca aagtgctcca tttcaagaat atcaatatca tacttttcta gatccagatt
    12661 tgaaacaatg gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa
    12721 aaataagatt tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca
    12781 tatcagcgat gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat
    12841 aatccccaaa agcagttctg agatagacat catagccgat tggaataggc atctctgttc
    12901 cttcaaatgg caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt
    12961 agccaggacc tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca
    13021 tttctttctc agcttttttc cagatgcgat aacggagaga ttttggagtc aaacccagta
    13081 aaatgcgact tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa
    13141 agagtgaata aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat
    13201 aataatccaa aggcaaaaca tccaaggtca gaccatgtgg caaatctaaa tcctgctgat
    13261 aaggcttgat acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa
    13321 aatccttgtg actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg
    13381 ctaatttctc ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa
    13441 atcccttgtt tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat
    13501 gttctttaca aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt
    13561 ttaaatcagt catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca
    13621 aggggtgaaa atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct
    13681 atcaaacttt gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt
    13741 caccttgccg taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt
    13801 gtttttagca gcctgcggct agcttcctag tttgcacttt aattttcatt gagtattatc
    13861 ttatctcaag cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc
    13921 caagcctcca taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt
    13981 ttcaatacca ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata
    14041 gggtacgttg gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag
    14101 tttagtggga tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt
    14161 acggccgtaa tccgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc
    14221 attcatctgc tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta
    14281 taaatcatct ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc
    14341 atcaatcgtc accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc
    14401 aaccaaggcg tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat
    14461 ttctgcccct ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc
    14521 tgtctgtttt ctaccattaa tcacttgact ataaccatct atatagacca aattatcacg
    14581 catgaaactg actagcttca ttttcttatc tgagcccccg acatttaata ccataataga
    14641 gtcagttcgt gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat
    14701 attaactcca tctctagtgt cctgaccatt aaagacttct acttgagctg cccgggcatc
    14761 agcagttttc tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa
    14821 agccacacag accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg
    14881 tcttttcttt tttggaggga aagagagtgc ttgtgatttg gattgtgagc gactccggtt
    14941 cgcatagctt ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt
    15001 tcccctagca agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt
    15061 gagatagtga atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg
    15121 attttcttta ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca
    15181 cccagaattt tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag
    15241 tccttatcga tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt
    15301 ggacgacttt caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta
    15361 taaagtgcac ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt
    15421 gcttgcaagg gaatactagg cttttcagct cctagaaccc agaaacgtgt gaaattggct
    15481 tccatttcct gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta
    15541 ggtgcaactg ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct
    15601 gtactagctg ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct
    15661 tgagccaagg cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc
    15721 atcaactgct gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga
    15781 aaaagatagt ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca
    15841 gaatagtcca ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc
    15901 tgcaattcct catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga
    15961 cctagataag ctattttcat cttagttcct ctataatttc ctctgggctt agcttggtca
    16021 catccaaaac ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta
    16081 ctagttcttc cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctgcga
    16141 tacgtaggta gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga
    16201 gtaagtcacg atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg
    16261 tttgtagtaa atcagctagg acttctgatt ctacatgacg aaaggctgct tctccctttt
    16321 cagcgaaaaa attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa
    16381 ggtaattagg gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata
    16441 acaccttagc catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg
    16501 atggcttctg cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct
    16561 gtcatcatgc cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat
    16621 ttccctttga taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag
    16681 gcgtctgcca caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg
    16741 ataactgtta caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc
    16801 aatcgtggaa tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacaatc
    16861 aaggtagcag atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca
    16921 cgaatgacat caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga
    16981 cgagaatttg gagcaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct
    17041 ggtacgacca ccttctgtcc tgtcaatttt tgtggcccct ggactgtgat tttcttacca
    17101 tccacactta aatgaccacc aaattgttgc aacatatctt cagtatgatt acgggtgtac
    17161 tctttttcga taataactga ctccccctta gcttgtaagg ctgcaaacat caaggctgac
    17221 ttgacttggg cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct
    17281 tttaagcgaa ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt
    17341 ttcagtggaa gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc
    17401 tctacttcga aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa
    17461 tttcccatat taagggcatt ttgtggcgct tttaagccag ccatgcctac accttgaatg
    17521 gtaataaccc catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc
    17581 gaaagaacgt cttcacctcg cagaatatca taaaccttgg tctcaccctc agccaaactt
    17641 ccaaagataa tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt
    17701 aaatggcgaa tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct
    17761 attttatcat aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc
    17821 ttatttcagc aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat
    17881 ggccaattgt tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt
    17941 accaaagcct tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag
    18001 tttttgaatt tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc
    18061 tgctgcaatc gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc
    18121 gcgactgagt tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga
    18181 cgactgtata gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat
    18241 ttttaaatga aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga
    18301 tgttaaccaa ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat
    18361 caggaacgtc aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca
    18421 tggtctggcg ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct
    18481 tactaatggc ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa
    18541 tggtctcgct attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc
    18601 gggtcatatc tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat
    18661 agaccgcagt ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag
    18721 aagtgacacg atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa
    18781 gcagatcctt catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat
    18841 aataggcatt ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag
    18901 ccatgggatg ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat
    18961 ccacaatggt tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca
    19021 aattggccaa ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga
    19081 catctgccaa aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt
    19141 tcaaggcgat atctctcgaa gcttgactac gattataacc taaaatttca taatctggat
    19201 gatcgcgttt gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga
    19261 ttgtttttgc cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg
    19321 cttcttttag ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa
    19381 ccgttgctac aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc
    19441 tctccacggt tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat
    19501 aaagagtagg aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac
    19561 caccttcaaa accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga
    19621 gaatttcatc cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt
    19681 ccaccccttt aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc
    19741 tatcccattg gacataggaa ccaagaccaa ctggaacgcc tccgacgact gtctccacaa
    19801 ccccaccgat ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt
    19861 ctcgttcttg gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga
    19921 ctgtcagatt ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa
    19981 tctccatatc cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg
    20041 tggtttcacg agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa
    20101 tccccccaac caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa
    20161 ggcggtcttc aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga
    20221 tgacatccat agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga
    20281 caacctggtc actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc
    20341 taagatcctc attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa
    20401 tagctgttag acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt
    20461 attttaccaa gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa
    20521 gctctggcac caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag
    20581 cctgataaag cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac
    20641 acatctctgt gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct
    20701 tggaaatctg taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg
    20761 cagtcgcttc gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat
    20821 tgtccaactc atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg
    20881 tctctgcatg ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca
    20941 gttctggatc ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc
    21001 tttttccgag ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg
    21061 tccccaccat atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat
    21121 caacctgagc tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag
    21181 aggctacaaa gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc
    21241 tacgagtcag accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct
    21301 ttctttcttc accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc
    21361 tgagcttgac cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct
    21421 tttgcggttg ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa
    21481 tctgaatatc ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct
    21541 ttctttattg atatttttct gttaaagact gccaaatctc ttctgtcggc attttcttgc
    21601 ctgtccacag ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg
    21661 ctggattgcc ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga
    21721 tatctgcaac taagagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc
    21781 catccatgcc cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca
    21841 gttcagaaac atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact
    21901 tgtctaggta aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac
    21961 tgacgccatc caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca
    22021 gggtcatctt tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat
    22081 ctgtattata tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca
    22141 agcgcgcttc atcgctcagc tcatccaaat aaggaatcac ctgctcctta tagggcatgg
    22201 acagattgat gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac
    22261 tcgcttcaat ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat
    22321 tgtggatgaa gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg
    22381 tatagccatc aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc
    22441 tgcccagggg cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc
    22501 gcagtgatac gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca
    22561 ggattgagcg ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg
    22621 tgagccatca ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt
    22681 tccatcatgt tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag
    22741 tccagcattt cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt
    22801 tgatagagtt gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt
    22861 tctccacctt cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca
    22921 aaaatggctg gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca
    22981 atgatgtcgg catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt
    23041 ggcattactg aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat
    23101 tactactttc atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa
    23161 tctggtaact tcttcctgca aagcctttat caatttgttc tgtaaatttc tgacgggaaa
    23221 cattggcagc attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct
    23281 gggaaatcaa cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa
    23341 agctaggcgg atctaggaca atcacatcgt aggtcaagtt tttgcgtttg gcatatttga
    23401 aatactcaaa gacatccatg actataaaac gacgctcgtc tgtgctgagc ccatttgcct
    23461 gaaaatgcgc ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc
    23521 tagctcctcc catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca
    23581 aggatttacc catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga
    23641 aaattcctgt catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa
    23701 cagtgaaaaa gtcaggtgct tcttgaccat aaacatgggc agattcatag tccaaaccct
    23761 taaagcggat tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg
    23821 atatagtctg acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc
    23881 cataaaggtc cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg
    23941 cagttgtcaa atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg
    24001 tttcaaagaa agcttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct
    24061 tgttttgctg agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta
    24121 cttcctgatc cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct
    24181 tagcaagctt cttttcaacc cttttgctga ctcttattct attcataact accattatat
    24241 caaactttta gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa
    24301 aaatggtata ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa
    24361 aatgctcttc cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta
    24421 tgaaactagc ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt
    24481 gtctgtcaaa tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcag
    24541 tagatatctg gaaaatttga ttttatagaa aagccttttg ttacaaactc aatatactat
    24601 caataaataa tattatagaa gcaacaataa ttaaaatttc acctatttgc atcattctat
    24661 ttcgaactct aaatatatgt tctatcaaaa atacttggat cacacacatt ataggaatta
    24721 acgtttttga aattgaaaaa tatcccaata aataaactat aaacaacaat aatagaacta
    24781 tattatattt cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt
    24841 tacaactaca ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagca
    24901 accaactatc tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc
    24961 caaaaatagc aagagcaagc aagacgataa gagctcctac tcccaagttg atggcaagga
    25021 taggggagag agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac
    25081 tataaataaa caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa
    25141 tgctactcca attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga
    25201 tgacactggc aatgatccag actacaagaa ggtaaatcat cgaaaggatg gacaagccta
    25261 gatatagaga aagaccgagc aaagtcagaa ctggtaaaaa ggactgaaca gcaaagataa
    25321 tccaaaattt cactttcaca taacgagcaa agtcaaaggg taaactcttc agaaaatcaa
    25381 cattttccct ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa
    25441 ctgctataaa cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa
    25501 ctatctgaga atctcggatt ttggaaatca gactgatcat catgagataa ggaaggaaag
    25561 cacttgtaaa aagcactgta atcacaccag tcccctatcc caagagggtg aggtggtagc
    25621 gtaaaaccat acggaaaaag ccctttttag tagttgaaat cctctccttg ctgcgacgtt
    25681 cttttttgac cttctcctca ctgttaagca ggatcacgtc ataaaaacga ggaaggacct
    25741 tctttttggt cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccacta
    25801 aggcttctgt cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga
    25861 gaaatggaat gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga
    25921 taaatattaa aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat
    25981 actttctgaa gaccctagtc tgagccaaga aatgtactgc cactaccgtc actaaagtaa
    26041 cagagacaaa taataaggtc aaggacagta gcatcaaagg caaacccagc caaagagaag
    26101 gagctagact aatatagagg gctagaaaat aagctaggat tggtacaatt ccagttagag
    26161 ctggcaagag gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg
    26221 gcctatagga ggccaggtcc ttactctcat aaaagacatt gtaaaaggca gtgaaagaag
    26281 ttgaaaaggc cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct
    26341 caaaaggaaa atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa
    26401 tgtaagaact taggactcta gcagaaacat ttactttttt cccaggattc ttagcctgct
    26461 tctttcgtag attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta
    26521 attttttaat gaccttgaga cgcatccgca acctcctctt ttctaccagc aagactaagg
    26581 tagatacttt ccaaaaactg gtctgggtgg tctttcctca agttctctac actaccacaa
    26641 tagatcaaat gccccttttt caaaatagca atccgatcac agacttgctc ggctacctca
    26701 aggacatgag ttgaaaacaa gaccgtcttg cctttttgtg catgttcctt catcatttgc
    26761 ttcaaatcaa aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata
    26821 tcaggagcag acaagagtgc cccaatgaca aagactttct gacgcattcc gtgagaaaga
    26881 gtttcaataa cctgatagcg gttttcagca aaatcaaaaa cgttcaatag cctagctaga
    26941 ctagtctcca agtcagagct agtcagatca taggatgaag cgatcaattc ccaaaattca
    27001 ttggccgtta agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgtttg
    27061 atcgccaagc gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt
    27121 gaaatgatac tgactaggga ttttatggtg gtcgattttc cagccccatt atgaccaatc
    27181 aagcccataa tctctccatt ttcaatctgc aaattgagat tactcaaggc ctctttatca
    27241 ccatacaact tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta
    27301 ttatacatcg ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt
    27361 aaaatagttt ccttctatct tacgcaaacg tttgcgccga gagatacttt atgatagaat
    27421 aaagaacaag attgacaagt aagaggaaac atcatgcaaa atcaaacact catgcaatac
    27481 tttgaatggt atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca
    27541 cacctagctc atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac
    27601 gaaaaagatg tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa
    27661 gggactgtcc gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt
    27721 aaagaacagg gaattcaacc tatggccgat gtagttctca accacaaggc tgctgccgat
    27781 aacagggaag cctttcaggt tatcgaagtt gatcctgtag accgtacagt tgaacttgga
    27841 gaacccttca ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctat
    27901 aatggcttcc actggcattg gtaccacttc accggtacag actacgatgc caaacgcagt
    27961 aaatctggga tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc
    28021 gataacgaaa acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct
    28081 gaagtcatcc aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct
    28141 ggtttccgtt tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc
    28201 gatatgaagg aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac
    28261 aaggaagcca atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt
    28321 cgtctccacc agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc
    28381 attttcacag atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac
    28441 cacgataccc aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca
    28501 gcctatgccc tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac
    28561 tatgggattt caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta
    28621 gccatccgaa aagacttggc ctatggagaa caaaatgact actttgacca tgctaactgt
    28681 atcggttggg tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat
    28741 gaccaagaaa acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta
    28801 gatttacttg gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc
    28861 cctgtctcag ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata
    28921 accaagctag gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg
    28981 gatagatctt tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta
    29041 gcttggttgc ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg
    29101 attggtgcta attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca
    29161 aggacattga ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt
    29221 tgtttccagt tatctgcaaa agtacgaagg gcaccggcat cggatacaga cacttgacta
    29281 gcaatgtaac gatgaccgtt gacttcctta gcatctttga agatatcgcc tgcggctgca
    29341 gctgcggctt tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga
    29401 agtccttcta ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca
    29461 gctttaagag catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc
    29521 aagatacggc gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc
    29581 tcagaagtgt tgccaacatg agtaccacca caaagttcaa tagagtagtc accgatagtc
    29641 acgacacgaa cttccttgcc gtatttctca ccaaagaggg ccatagctcc catttcttta
    29701 gcagtgtcaa tatccgtttc aactgtcttc acttcaagtg cttcccaaat tttctcgtta
    29761 acttgctgtt caatcgcacg aagttcctca gcagttactg cttggaagtg ggtaaagtca
    29821 aagcgaagga attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata
    29881 ttgtgaaggg cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg
    29941 cgattgctat caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca
    30001 actgtatgaa gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaatc
    30061 ttacctgact catccaagat ttgtccgtag tcagctacct gtccacccat ttcagcataa
    30121 aatgacgttt ccgcaaagat aagagaggca gttccttctg aaacagctcc tacttctgca
    30181 ttgtcagcaa cgatagctac caatttagaa gacaattggc tagtattgta gttgaagaca
    30241 ctttctacag tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca
    30301 gctgacgcac gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct
    30361 acagtcatac cagcctcttc agcaatttct tcagtcaatt caactgggaa cccataagta
    30421 tcatagagtt tgaagacatc tgaaccagcg ataacagatt gacctttttc tttcaagtct
    30481 gctacaatgc cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct
    30541 tcgctcttaa cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt
    30601 tccatgattt ttccaacagt tggaaccaat ttgtaaagga aaggctcgtt gattcccaat
    30661 ttttgaccat gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca
    30721 tttcctggaa gggcaccatc accgatggca aatgaaagtg aacggatgtg gtcagcgatg
    30781 accttgaagc tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact
    30841 tcacggataa tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg
    30901 gccaccaaac gctccaaacc agcgcccgta tcaatgttct tatgtggcaa ttccttgtat
    30961 tcgctacgag gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttca
    31021 atataacggt cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca
    31081 aaggcttccc cacggtcaaa gaagatttct gtatctggtc cagaaggtcc cgcaccgatt
    31141 tcccagaagt tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag
    31201 cggttgtaag aatctttatc gtctggatag taggtcatgt aaagtttttc agcagggaaa
    31261 tcaaaccatt cagggcttat caaaagctca taagcccaag tgatagcttc gtcacggaag
    31321 taatccccga tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc
    31381 cctacgtttt cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt
    31441 tcagggataa tggtcccgtc aaagtatttc ttaagggttg ctaccccaga gttgatccac
    31501 aaaagagttg ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg
    31561 gtcgcccaga aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg
    31621 tctccttatt tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg
    31681 acacagaggg aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta
    31741 gaggtcagat ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc
    31801 aatttgaaat tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca
    31861 tacttatctc gccaaaaggt caacttctta cgaatgacaa aactcgagcc atccagaagc
    31921 tgaatctcaa aacgaggaag caaggtcaag atttctttac tgatctgact gacttgttca
    31981 ccagccgcat catagatggt aaaagttttg ggaatcttaa aaaatgatcc ctccacctga
    32041 taggcaattt ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt
    32101 tgtttgacaa gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac
    32161 gaagggcgaa aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta
    32221 tgcaattgta tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt
    32281 tctctggact aagacaagtg aaaatcaatt ctcaactttc ttattatatc gtttttttaa
    32341 tcttgcgtca actggaaatg atctccgttg aattagacca attccctaca tctctgatta
    32401 cttttccagg atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt
    32461 actaaacaca gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga
    32521 ctcagttgtt aggtattgtc gatccaagcc atcctttaaa tggaatagta tagcagtttg
    32581 gttaacaatc ataaaggttg gccagaaact tttgttgaaa aaagtagaca ttttcattat
    32641 ttgttgccgc tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct
    32701 agcctcaagc tgtacttgag tacggcaagg caacgctgac gtggtttgaa gagtataggc
    32761 ttagtatact actaggcaag caaataagca aataaacaac tagaatagaa aaagataggg
    32821 ctctaaaaac tgacttctat tccttaaaaa cgaaccagct tgactgattc gtcttcttac
    32881 gtttatctcc tacttccgat acattttaaa ctgtaggaag aggtcgctat atttccctgt
    32941 ccatttatgg tcaaatttct cataaatttc taggtgtttc atggtttcaa catcgggata
    33001 gaaggcctta tcttcctttg tttcctctgg gagcaattcc ttcgctggta tgtttggtgt
    33061 tgaatagccg acatactccg cattttggag agcattttca ggtttcaaca taaagttgat
    33121 aaaggcatag gctgagtctt ggtttttaac tgttttggga atgaccatat tgtcaaacca
    33181 aagattgctg gcctctgtcg gtaccacata acgtagattt tcattttttt ctaacatttg
    33241 gctggcttca ccagagaagg tcacgccgat tgcaacgtta ttctgaatca tatagccctt
    33301 catctcgtcc gcaacgatag ccttgatatt tggagtcagt ttgtagagct tatccactgt
    33361 ctcttccaac tgctgcagat ccttggagtt gaggctgtag ccgagggaat tgagtcctag
    33421 tcccagcacc tcacgcgccc catcaaagag catgatagaa ttcttatact ccggcttcca
    33481 aaggtcatcc caatgctcag gcgcttcatc taccatggtt tcgttgtaga caattcctaa
    33541 ggttccccag aagtaaggga tggagaattt attacctggg tcaaaggact ggttgagaaa
    33601 ctctggtccg atattttcga ttccttcaat ttttgaataa tcaagcggaa ccaagaggtc
    33661 ttcgtccttc atcttgttaa tcatgtattc acttggaatg gcaatatcgt aggtcgttcc
    33721 accctgcttt atcttagtgt acatggcttc gttggagtca aaagtctcgt actgaacttg
    33781 aattcctgtt tcttctgtaa actgagtcaa gagttcagga tcgatatagt ctccccagtt
    33841 atagataacc aatttttgac tatctcgact attgatttta ctatctaaat gagtcgcaat
    33901 tccccacaag acaaggataa tcgctgcaat tcctgctaaa aatgaataga tttttttcat
    33961 gcttgctcct ccttctcacg agagataaag taataaccta caactaggat aatactaaag
    34021 agaaagacta gagcagacag ggcattgatt tctaaggaaa tccccttgcg agcacgagag
    34081 taaatctcga ctgatagggt tgaaaagcca tttcctgtta caaagaaggt cacggcaaag
    34141 tcatctaacg aataggtgaa ggccatgaaa taaccagtaa tgatagacgg agtcaggtaa
    34201 ggaagcatga tttccttgaa catctgaaat tgactagctc ccaagtcata ggccgcatga
    34261 atcatgtcgc cattcatttc cttgagtcga ggcaagacca tcaagaccac gataggaatg
    34321 gagaaggcca cgtgactaga tagaacggtc aaaaagccaa gtgaaaactt gagttgggta
    34381 aagagaatca agaagctagc accaatcata acgtcaggcg caaccatgag gatattattg
    34441 agtgatagaa aggcttcttg gtatttctta cgagactggt agatgtaaat ggcaccaaaa
    34501 gtcccgataa tggtcgctat caaggctgat aggaaggcca agaaaaatgt ctgagccaaa
    34561 atcagcatga gtctcccatc tccaaacatg gtttcaaagt gagtccagct aaaacctgta
    34621 aagctattca tatcatcacc agcattaaag gcatagccaa tcaagtaaaa gataggcagg
    34681 tagaggacca gaaagaccag tcccagataa aggttggcaa attttttcat cgttctctcc
    34741 tttccttagt cacccacatg gtgatgaaca tggtcaggat gagaatcaca ccgatggttg
    34801 aacccatacc atagttgtca ttggttagaa aattctgctc aatagccgtc cccaaggtga
    34861 taacgcggtt cccaccaatc aaacgggtca gcatgaagag actcaaactt gggataaaga
    34921 ccgactgaac cccacttcgc acaccgttca tagatagagg gaagatgaca tgacggaagg
    34981 tctcccactt agttgcacca aggtcataac tagcattgat gagattatta tccatgtcgt
    35041 ctaagacatt gaaaatcggc aaaatcataa aggggagctc gatgtagctt gcgacaaaga
    35101 taaaggaaaa atcggtaaaa agcaactgtt gtgaaccaat tccgataaat tccaagaatt
    35161 ggttaataga gccattttga ccaaaaatcc cgataaaagc ataggcttta aggagcaaat
    35221 tgatccaggt aggaaggata atcagcatga gccagagttg acggtgcttg agacgggtca
    35281 aaaagagggc tgttggatag ctgataagca aggtcacaaa ggtcacaatc cctgcataaa
    35341 gcactgagtt gaaactcatt ttgaggtagg tcaagttttg tgacgcaaag taagatttat
    35401 aattttctaa actaaactgg ccttcaatgt tgaaaaagga ttgtccgaaa atcaagacca
    35461 agggtgccaa tacaaagagg gcaatccaaa gcatgtaggg cactacaaag agtttagagc
    35521 ttgttttctt catctctttc ctcctcgatc gcattgatca gacctgcttc ttgctcttcg
    35581 atttccacgt attcttcgat acgagcatcg aactcttctt cggtttcatt gagacgcatg
    35641 atgtggatgt cttctgattc aaagtccaga ccgatttcct cacccacgat ggccttacgg
    35701 gttgagtgga tcatccattc atttccaagt tcgtcatagg cgataatttc ataatgaact
    35761 ccacggaaga gctgggtgtc gaccttaact tggagtttgc cttcttcagg aagggtaatg
    35821 cgcaagtcct ctggacgaat aacgacctca acaggttcat ttggcttcat cccaccatca
    35881 accgcttcaa agcgtttgcc gttaaattcg accaagtagt cctcaatcat ggtacctggc
    35941 aagatgtttg actccccgat aaaggtggca acaaagtggt tgattggctc atcgtagatg
    36001 tccacagggg ttccagactg gacaatctcg ccatcattca taacgaaaat ccagtcactc
    36061 atggcaagag cttcttcctg atcgtgagtg acaaagacaa aggtaatgcc caatcgttgt
    36121 tgtaattcac gcaattcgta ctgcatgtct gttctcaatt tcaagtccag cgctgataaa
    36181 ggctcgtcca acaagaccac acggggttgg ttgatgatag cacgggcgat ggccacacgc
    36241 tgacgttgtc ctccagaaag tttgcggatg gaacgttttt cataaccttc caactgaacc
    36301 atcttgagaa cttccgctac acgctgctcg atttctttct tatcaatttt acgcaagcga
    36361 agtggaaagg caacattttc aaacacattc atatgtggga acaaggcata ggattggaag
    36421 acggtatgta cgtcgcgctt gttggttgga atatcattga tacgaacacc gtctagcatg
    36481 atatctcctg tcgtcgcatc cagtaaacct gcaataatgt ttaggatagt tgatttcccc
    36541 gaaccagatg cacctagaag ggtgtagaat ttcccttctt ccaactcaaa gttgatgtct
    36601 ttgagaacct tggtgttgct gtcttcaaaa actttagaga cgtttttgaa ttcgataatt
    36661 ggttttttca attggcataa attccttctt tttcatagat taaccgatcg gggctctgtc
    36721 aggtccccac tacctcttgc agggagtaaa accacctgca tacatcttcg ctaccgatag
    36781 gctttcaccc aagatccgga cttctctttc aagcgtaata cctgagtgtt ccttgacttt
    36841 ttcgataacc gattggatca agtcctcgta gtctttggcc gttccatctg cgacattgat
    36901 cataaatcct gcatgctttt ctgacacttc tacgccaccg atacgatagc ctttcaagcc
    36961 agcttctgaa attaactgac ctgcaaaatg cccgactgga cgcttaaaga ccgagccaca
    37021 agatgggtat tccaaaggtt gcttgagttc acgtaggtgc gtcaagcggt ccatttcctg
    37081 cttgataacc tgatgggttc ctggagctag ggcaaattta actgacaaga caactgcacc
    37141 agactcctga atagctgaat ggcggtaacc aaaagccaag tctttagcag acagggtttc
    37201 gatttctcca tccttggtca agaccttaca agactgcaag atgtgagcaa tctcgccacc
    37261 ataggcaccc gcattcataa agacagcacc gccaacgctt cctggaatac cacaagcaaa
    37321 ctcaaagcca gttaaactat gacggagggc aatgcgagtt gtttcaatca agttagcccc
    37381 agcttctgct tcaatggtat agccatcaac agaaacgtta ttgagcttgt cacacaagat
    37441 gacaaatcca cgaatcccac catcacgaac gatgatattg cttgcattgc caagaaccat
    37501 ccaagggata ttttcttggt tggcaaattt cacaaggcga gccaactcaa aacgatttcg
    37561 tggaaagacc aaataatcag cctctccacc tacttttgta taactatagc tatgcaaggg
    37621 ttcctgaaaa cggatatcaa ttccttctaa gatttcaagc attttttctc ttacagacat
    37681 gtcactcttc cttttccaaa attcattcca ttataccatt tttagagaca tttgacgacc
    37741 ataaaaatac cttgtttgga ttttgcataa gaaaaagagg ttcccccctt tttatgattt
    37801 tttacaaaag atttccttgg ttccataggc gaccagaacg agctccagtg ctagaatcac
    37861 ttcaaccaag actggatttg tcaaccagcc tacttggaaa agagatggtg ccagatcaaa
    37921 gaaggcatgc aagccatagg ctgttaggag ataaatccat ttcttctggc gaacagcttg
    37981 gtaaacccaa actgtcaaaa gtaattggaa accaagcgcc aagattcgct caaaaccaag
    38041 caaataaatc tgccagaccg aaagtgactg aatggttttt aacatatttt cagacagtaa
    38101 ttgcataacc tgtggattct gagtttgaac tgccgaaaga acaatgtaaa gattgagtaa
    38161 actagtaagg cctagaaaaa tcaactccaa gccaccatgc cccagtccat aggccaaggc
    38221 gtctgccttt tccaaacttc tctttttctc aaaccatttg aagaaaacaa gacgagccgt
    38281 ttcctcaaaa aatgctgcca tggctaggcc atagataata tagataagcg gatgatcttg
    38341 caagagggca atactaccgt ctttttgagg gtgcaaaatc aagatatgca ccagtttttc
    38401 caaaatctgc gaagagacaa agaaagcgac tgcacccaag cccaagacag ctagattaat
    38461 ctggtatttc tttttggcaa accaaatgct tcctatcaga aaagctagca acagcaacat
    38521 ggtaataatg atatgaatgg tcattttctt ctcctattct gccttttcaa tatctttttt
    38581 catctcgtca acattgaact tagcaaacaa gtattgacgg tcttggactg ggaaacgttg
    38641 gtccaactgg tcaactgctc ccacctcgat aatgccttcc ttgatgacaa aatccatgac
    38701 atgtccaccg aaggtcaaat catctgatat gaagtgcaga tggtagcctg ccacactgac
    38761 cccatggaaa atctcaggcg tccagaaacc aacaatagtc cccgcaacat tgtcacgact
    38821 atattccggt tgatgggttg cgacatcagc aaacttggta tcgggtgttg acttaggaat
    38881 catacgcaca tgcatatgta aaaattcccc ccgaatcttg atagagcgga aaagattttc
    38941 cccatcataa taagactcaa ttcgttcttt caattccttg tctgtcatct caaagcgctg
    39001 gcggaaaatg acctctgcct gatgcggtac cactgcagcg taaggaataa gggcatctgg
    39061 tgacacttcc acaatttctg gctggtctcc tgaccctttg gcctgataag ccttgccatc
    39121 caagacaatc aattccccat caatggaatc caaggttccc aaaccaaggt caccatgttc
    39181 tagcaattct cctactgtca tagtaccacc ataaaggcca gccatcaagg ctccaagagt
    39241 attgtattga aataatttca ctggttcctg cacgttctta tccattcact ttcttgtctg
    39301 ttattctata aatcttactc ctaagtatac cacatttgcc cctagatgtg aacgagagaa
    39361 acgttctaga cattgccaag aaggaaaaaa aagggtacaa tgtaacaaaa tcaagggagg
    39421 tctggaatga agaaacaaag caagtacaaa gaggtcgttt cctatctgaa aaatggtatc
    39481 gagtctggac gatttccgac gggtagtcgc ctgccttcta tccgtcaact gagccttgac
    39541 tttcactgca gcaaggacac cattcaacga gccctgctgg aattacggca cgaacaatac
    39601 ctctatgcca agcctcagag tggctactat gtattagaac aagggcaaca tcaagaccta
    39661 gaaatcgagg ttaccgacga acatgccagt gcctatgacg atttccgact ctgtgtcaat
    39721 gaaaccttga ttggccgaga aaactacctc ttcaactact atgacaatca agaaggatta
    39781 gaagacctaa gacagtccat tcacaaactc ctctttgagc aagctctcta ctgcaaggct
    39841 aaccaactag tactgacttc tggaacccaa caagccttat ttatcctctc tcaaatatcc
    39901 tttcctagac aagccaagga aatcttggtg gaacagccaa cctaccatcg gatgaatcgc
    39961 ctcttgattg cacaggggct ggactatcaa acgattgaac gaggcattga tgggattgac
    40021 ttggaggagc tggaaggcca cttcaaaaca ggaaaaatta aatttttcta caccattccc
    40081 cgatttcact atcctctggg acattcctat tctgagcaag acaaacgatc tattcttaac
    40141 ttagctgcca agtatgatgt ctatatcgta gaggacgatt atctgggtga tttggactcc
    40201 aagaagggcc aaaccttcca ctatcttgat acagaggagc atgtcattta tatcaagtcc
    40261 ttctcgacca gcctttttcc tgcccttcgt attacagcac tcattcttcc aaatgctatc
    40321 aaagaagcat ttgtggccta caaaaatatc ctagactacg acagcaacct cattatgcaa
    40381 aaggccctgt cactctatat tgacagtcaa ttgtttgaaa aaaatcgttt ggctcgcttg
    40441 accaatcatg aatcttacca aaaacaaatc gaggaaagga taactaaaac accttgtccc
    40501 cttcctcatt atcccctaca cgatggttta ttgctagacc tgagacagta tcctaaaatc
    40561 gccagtctca aacacagtca actgggcttg gacttctttg aagaggccta tttgagcacc
    40621 tgtccttatc aatttgccaa ggtgtcccta gacaatctgg aaaatgtttt aaactattta
    40681 aaagcagaat tggaatgaca tccaactctg ctttttctta ttcttcaact tcagttagac
    40741 ttgctgcttt ttcaagatag ctttggtaag ttccttcatc cttaagtttt tggatgacct
    40801 tgtctaccac ttctttcaaa tcatcactat tttttctaag agcaacggca ttggcgtcgc
    40861 cgtccttcat cttcaagctg acagttgcga cagctaagcc agcgttttta gcagcataac
    40921 taagtgcaac aggctcatcc atatgaacag catctatttt tccagcctgc aattcattga
    40981 ctgcttcacc catattagtt agggaagtta attgagcttt tggcaattgt tccttgacca
    41041 ttgattctgg aacagtccct ttttgggctg caatattagc actttctagg ctagttaaat
    41101 ccttgtattt ttccacatca gccttacgaa ccaagaaact aatcttgttt tcatagtatg
    41161 ggattgaaaa atcaaagact tcttttctct cgtcagtagc actaattcct gcaactgcta
    41221 ggtcagcctt accagtttga agactggtca aaacattgtc aaaactcatg cttaagattt
    41281 ccaacttaac cccaagttca tcagcgatag cctgagccat gtcgatgtct gcaccgacta
    41341 cctggttctt tccatcaacc aatgattgaa attcaaaggg tgcatagtca ggactggttg
    41401 ccacaactaa tttccccttt tgcttaatgg cctcaacagc tgactgagaa ccattagaac
    41461 ctgactggca agctactaag aagaaacttg caagaaaatt acataaaaca aatatccatt
    41521 tttttgattt cataaataaa caacctttct gttaattttg tataattata acgatatcca
    41581 agttacttgt caagtgtttt ttaaattttt atctcaaaaa tattttttcg ttcaaaaaaa
    41641 ggagccatca gttgatttca agctcctttt tatacagaat taaactattt tatagttcga
    41701 caatcttacc tgtttcaaag tagacaaccc attcacagat atttttagca tagtcaccga
    41761 tacgctccaa gtaggaaata acttggaaat aatcacgacc cgtaacaatg gcttctggat
    41821 ttttcttaat ctcttcagtc gcaaggtcac ggatagtttc aaaatagtgg ttaatttgct
    41881 catccatgga ggccacccgg tatgcgtcgt caacagaacc attaagataa agatcaagtg
    41941 ctgcttccac aacgctttta acttcacgtc ccattttttt aatttcttcc tctacagctg
    42001 ggatgcgttc ttcccccttc atacggatgg ttgcctgggc aatggctaca gcgtgatccc
    42061 ccatacgctc cacatctgat acagccttaa ggacagtcaa gactgtacgc aaatcttgag
    42121 agactggttg ttggagtgcg atcatttcaa atgatttctt ttccagtttc acttcgtatt
    42181 catttacttc tgcatcatct tcgatgacct cttttgccag gtcacggtca tgcgtgacaa
    42241 aagcacgtac cgtacgattg atttgtgaga gcacttcttg tcccatagcg tagaactggt
    42301 tatgtaattt ctctaaatct tcttcaaatt gagatcgtaa catctttcat ctccttatcc
    42361 aaattttcct gtaatatagt cttccgtttc cttgtgttgg ggatcaagga acatctgctt
    42421 ggtatcatta aattcaatca aatctccatc taggaaaaat cctgtcttat cagagatacg
    42481 tgaagcttgc tgcatggaac gggttaccag aagcatggtg tacttgtctt ttagaccata
    42541 caaggtttcc tcaattttac cagctgaaat cggatccaaa gccgaagttg gctcatccaa
    42601 gaggatgatt ttaggactag ttgccaagac acgggccacg cagacacgct gctgttgacc
    42661 acctgacaat ccaatagctg aatcatatag acgatccttg acctcatccc agatagaggc
    42721 accttgcaag gctttttcta cggcttcatc cagaacctgc ttatccttaa ttccattgat
    42781 acgaagcccg tagacaacat tctcatagat agtcataggg aaaggattag gttgttggaa
    42841 aaccattccg atttccttac gtaattcaac cgtatctgta cgcggactgt agatgttgtg
    42901 accattgtac accacggatc cagttgtggt cacctctgga ttgagatctc ccatgcggtt
    42961 gagagacttg aggagggttg acttccctga tccagatgga ccaatcaagg ctgtaatttc
    43021 cttaggttgg aaagataggg aaacactatt caaagccttc tttttattat aatatacgga
    43081 caggtctgat acctgtaaaa tcgcatctgt catacggttt cctttctaac caaagtgacc
    43141 agatacatag tcattggtgg actgtagctt ggcattttgg aaaatagttg cagtcttgtc
    43201 atactcaatc aaatcaccca agtaaaagaa gcctgtatag tcacttgcac gagcagcctg
    43261 ctgcatatta tgcgttacaa tgatgatggt aaagtttttc ttgagctcaa acatggtctc
    43321 ttctagttgc atggtcgcaa tcggatccaa ggctgaggct ggctcatcca ttaagaggat
    43381 atctggctta acagagatgg cacgagcgat acagagacgt tgttgctgac cacctgataa
    43441 ggtcaaggct gacttgtgga gatcgtcttt aacctgatcc cagagggcag cctgacgaag
    43501 ggaggtttct acgatttcat ctaggacttg cttatcctta actccagcac gttcatgcgc
    43561 aaaggtaata ttacggtaaa ttgacttagc aaatggattg gggcgttgaa aaaccattcc
    43621 aatgtgttta cgcatttcat aaacgttgat ttctggacgg ttgacatcaa ttccacgata
    43681 gagaatctgc ccagttactt tagcaatatc aatagtatca ttcatgcgat tgagactgcg
    43741 taagtaggta gatttccccg atcccgacgg accaatcaaa gctgtaattt tatttctttc
    43801 aaattgcata tcaatcccct taatggattc atttttacca tagtaaacat ggacatcctt
    43861 agtagaaagg gctacttttt cttcaggaaa ggtaaggata tgcttctcat cccagttata
    43921 tgttgacatg gcttctcctt taggcagcgg ttaatttctt gtgtagatag cttccgaact
    43981 tacgagctcc aaagttaaaa atcaggataa agatcaggag cacagcggca gaacctgctg
    44041 atacaatggt tccatctgga atagtgcctt cactattgac tttccagata tggacagcca
    44101 aggtttctgc ttgacggaag atagagatgg ggctagtcac actgaggata ttccagttag
    44161 accagtcaag agctggcgcc gattgccctg ctgtatagat cagagctgca gcttcgccaa
    44221 agatacgacc agatgccaag acgacacccg ttacaatacc tggaagcgct tctggaataa
    44281 caacatgaac cactgtctcc cagcgagaaa tcccaagagc cagaccagcc tcacgttggg
    44341 tatggtgaac gtgtttcaaa ctatcctcta cattacgcgt catctgaggc aagttaaaga
    44401 ctgtcaaggc caaggcacct gaaatgattg aaaatccata ctcaaactgg actacaaaga
    44461 tcaagtaacc aaagagaccc accaccactg atggtaaaga ggacaagatt tcaatacaag
    44521 tccgcacaaa gttggtaaca ggaccttttt tagcatattc agccaagtaa atcccagctc
    44581 ccatagaaag aggtacagaa ataatcaagg taatgaccaa taggaaaaag gaattgtaaa
    44641 gctgaatgcc aatcccacca cctgcttgaa aagcagaaga ccttccagtc aagaaagacc
    44701 aagagatatg gggcaagccc cgaaccaaga tatagagaat caaggaagcc aagattgtca
    44761 caatgatgct agcaatcgta tagaggacag ctgttgcaag tttatctaat ttcttagcgc
    44821 gcataatttt tctttcctct ttctttcgta atcaatttaa tcacactgtt aaaaactaaa
    44881 ctcatcaaga gcagtaccaa ggccagtgac cagagaacat tattatttac agttcccatg
    44941 acagtgttcc caattcccat agttaatata gaagttaaag ttgcagctgg tgtggtcaag
    45001 gaagttggga taacagctga gtttccgaca accatctgga tagctaaagc ctcaccaaag
    45061 gcacgcgcca tcccaaagac cactgcagtg aaaataccag aacgggccgc cttcaagatc
    45121 acacgccaga tagtctgcca gcgagtggct cccatagcga aacttgcctc acgataataa
    45181 cgaggaaccg cacgcaagct atccgttgtc ataaaggtta cggtcggcaa aatcatgaca
    45241 aagaggacgg aaatccctga caaaatccca aaaccagtcc caccaaagac actgcgaaca
    45301 aagggaacga cgacttgcaa gccaataaat ccgtacacta ctgaaggaat cccaaccagg
    45361 agttcaatag ctggttgcaa aatcttcgcc ccttttggtg atacttcggt cataaaaact
    45421 gctgcaccaa tagcaaaggg tgttgcgata agggctgaga gaatggtaac gataaaggaa
    45481 cccaaaatca taggaagggc accaaattct ttactagaag gattccaagt tcctcccaaa
    45541 agaaagtcaa agatattcac accattgaca aagaaggtcg acaagccttt ttgcgctacg
    45601 aaaaccaaaa tcatggccac aaggatgact atcaaagaaa gacaggcaaa ggtcaaacct
    45661 tttcctaatt tctccagacg agaattcttt gatggaagca acattttctt agctaattct
    45721 tcttgattca ttattgtctc ccttccaaca ctgtcacagt tccggcagca tctttttcaa
    45781 ccttcatttc cttaatcgga atatacttca atcctttgac aatcccttct tgggtctcat
    45841 ccgagagaac aaaattgaga aattctgcag ctaactcatt gggctgcccc aatgtataca
    45901 tatgctcata agaccacaag ggccaattat tgctacttat attttctgga cttaagtcat
    45961 agccattcaa cttcatgctt ttgaccgaat catctatata ggtaagagat aaataagaga
    46021 tagctcctgg actttttgat acgattgatt ttaccgctcc atttgaatcc tgctcctgac
    46081 tttgcatggc agactgacct tccataatga cagtatcaaa ggtagcacga gagccagagc
    46141 cggctgcccg attgataaca gagatgggta agtccttacc accaacctct ttccaattgg
    46201 ttacctcacc tatgaagatt tgacgaagtt gctctgtcgt taggttatca acatcaacct
    46261 ccttattgac aatcagagcc aagccagcta ccgcgacctt gtggtcaaca agagcagaag
    46321 catcaattcc gtctttttcc tcagcaaata catctgagtt tcctatatca actgccccag
    46381 actgaacctg ggacaagcct gtaccagaac ctcccccttg gacattgacc gtttttccaa
    46441 catggatcgt gccaaattca tctgccgcta cttcaaccaa gggttgcaag gcagttgagc
    46501 caacagccgt tatggattct ccacgatcaa tccagctagc acagcctact aaacaagccg
    46561 tcagccaaaa agcgataaga gacagagcaa gcttttttct ttttttcact gtttttctcc
    46621 tcgaaaataa ttatgaatac tgtgaatttt ttaagtagtt ctttatgagt tgacgcatga
    46681 attcttacca aatttctgcg caattgatta tttatataat ataggctata ttactctttc
    46741 ctaacctcct tttttcatat gtggataaaa tctcttgtct atcccttccc ccattgtcac
    46801 ccattatagt catttcgtgt ctctttttcc cctttttaat gcaagggaaa ttactctcct
    46861 tagatgataa tccaaaagct agaaaggtat ctcaaatctc tctactctcc cagactagtt
    46921 tacaactaaa aggaaaagat tctattttat gagaaatcta gtttacaagc ggtaagaacg
    46981 ctaataacta aacttcttgt actctttgaa aatctcttca aagcagtgtt ttgagctatc
    47041 tatggctagc ttcctagttt gctctttgat tttcatcgag tagtaaaact acatgtgatg
    47101 gcaatcaaga tatcaagaat catcctacta aaaaaatcca tactttcact ataacataga
    47161 ataagatatt tgactagcat tttcatttga atctgaggcc ttttggaaaa taatttttca
    47221 aaacatttcc agtaaccttt gcaaagccca agccattgcc tttaaccaaa acttggtacc
    47281 aaccatttgg cagactttct gccagctgaa cggtttctcc agccgcatac ttgacaaact
    47341 cttcttggcc aatttcaacc gactgttcga cctgactcgg tttcaaggct aaaccaagag
    47401 cgaaactggg ctcaaagcgt ttcttcttaa aagtacccag atgcagtcca ttgcgagcaa
    47461 tcttgagctt ccctaaatct ggcaaaagtt ctggcaagag ataaagctgg tctccaaaaa
    47521 tctgcaagat acccggtaga ttgaccttca aatggttttg ggcaaattcc tgccacaagg
    47581 caacttgttc acggctgagg ttactcttac ttgccttaaa tttaggagct ggattgttac
    47641 ccttaaactg tagatgggca acaaactgac cctctccctt aaactgatga gggtacatcc
    47701 gagccgtttc tggcaggtca ataccagcta ccattccatt gatatgctct actggcaaca
    47761 agtcaaaatc atactcttcc agcaaccaat tgacaatctc ttcgttttcc tcgggtgccc
    47821 aggtacaggt cgaataaacc agacgaccac cttcagctaa catggtcact gcatcctcca
    47881 gaatttctct ttgcaagcta gcacattgac tcggataatc taagctccaa tagtccatag
    47941 catcaggttg cttacgaaac attccttcac cagagcaagg ggcatcaaga acgattaagt
    48001 caaaatagcc tttaaagacc ttgaccaagc ggtcggcaga ttcattggtc accacgacat
    48061 ttgtcgctcc aaaacgctcc atgttttcaa ccaaaatctt agcccgtttg cttgaaattt
    48121 cattggaaac aagtagcccc tcccctgcta gataggctgc cagttgagtt gatttgcccc
    48181 ccggtgcagc agccaagtcc aagaccttca taccaggact gggttgggct acttgagcca
    48241 ccatttgagc agcaggttct tgcgaataaa ctaaacctgt agcatgctca ggcgatttcc
    48301 ctgaaacctt cccatagtgg ccccaagggg tttgagtaat ggcatcagaa aaggaaagtt
    48361 gctcttcttt taagggattg acccgaaagg ccgaaaccgc ttcctcctca aaagaggcaa
    48421 gaaaatctct tgcctcatct cctagtattt ctttatattt ttcaacaaat ccttctggaa
    48481 atttcattta agttcttttc ctttcgtaaa tataggactg aatttcctcc tgcatctcaa
    48541 gaggcaccat catgaccggc tgtctggttt gaaaatcagg agcttcacca aaaagggtca
    48601 caacccgata gcccagactt tcccctaaaa tactagctgc ggcataatcc catggttgca
    48661 gataggtgag ataggtcaac aaacgccctg acaaaatctt ggcaaaacta atggccgcac
    48721 ttccatagac acgaacacca agaaccgctc ggctcaaatc agccagcccc cattcattgg
    48781 tttccagcat accactattc cctgcaatga gaaaatctcc aagtggttta gttttaaaag
    48841 aagctagggg cctatcattt agacaaactg gaaattcccc accaccgtgg taacaatccc
    48901 ctttgaccac atcataaatc agaccaaact gtccctgacc attttcaaaa taagccatca
    48961 taacagcaaa atcttcctgc tgggctacaa aattattggt accatcaatg ggatcaatga
    49021 cccaaacctt gccctcttga accgaggctc gcagacaacc ttcttcagca caaatcttat
    49081 cctcaggata acgggacaaa atctcaccaa ccaagagttc ctgaacttct ttgtccagtc
    49141 tggtcaccaa atctgttgga gaggacttgg tttcaacacg caagtcttcc tgcatatggt
    49201 caagaatgta ctgacctgct ttcttaacaa gctctttagc aaattcaaat ttacttttca
    49261 agagaaatct ttcctttccc tttttctttg gcagcctgaa ctgctcggta aagtgaatag
    49321 ccactaaccg tttcaaattc tcgtcccaaa cgtttctctt cgctcttgct tggcacgacc
    49381 gctttgaatc ccttatagga gtccagtaac tttttagcct ctactttgcc ttcataggca
    49441 gcttcaacat cattaaaaaa agaaagcact gaagcaagtt cttcagtgct ccacgacaaa
    49501 tctagtgggt aactatactg tttgttcatt aactaatacc agctctcatt cttgcttctt
    49561 ttagttcttg cttacgataa ctacgaggga gaaaagcacg aatctcatct tcattaaaac
    49621 cgatttgcat acgcttggca tcaataataa ttggacgacg caaaagacta ggatactgct
    49681 caatcaaatg aagcaattcc gataccgaaa tactctctac atcaatattc aatttttgaa
    49741 aaatttttga acgagttgaa atgatgtcat cagtaccatt ttcggtcaag gaaaggatgt
    49801 gttgcaattc ttttcttgtt aaaggactgg tcataatatt gtgttccaca aagggaacct
    49861 tatgtttttc taaccaggtc ttagccttac gacatgatgt acagctcggt gatagaaata
    49921 gtgtaatcat gcttttctct tcttatctat actttgctac ttctattata caaaaaaata
    49981 aggcgcttga ctagggattt ttagaaaaaa agcctatttt ttcaggaaaa ataggctgtt
    50041 tgcgaacgat tgacacaatt ggatttggtt aattcactct taacgatggt tttaaacgat
    50101 atatatattt atatatgtaa attaaaaaca tctttccttt cacttcctac gacttttcag
    50161 acacagatag ccaaagaagc tttcatagag ggcaaaaaag aggaggaagg catgaagaaa
    50221 gaaggtctct ggcaaaatca taataacagg atccttggct ggatcaaaaa gccaggtatc
    50281 atctcccaca aagagaattt gatggaaaag agtaaagaat tggtcaaaac caatcaaaac
    50341 tcccccaagt ccaatcatca caggtaagac tactagagcc aggagacttt ttcgataaag
    50401 agacaaaaag tcctttttca caatcctatt gacaaagaca tagaaacttg gcagtgtcac
    50461 tagagctact agctgaacca aatgaaagag attcttgacc actgcgaaat ggtgcaaacc
    50521 agctgctgac gaacgaaaat caggcatctg taagacctga ctaaaaggat tggtcagata
    50581 attcatcaag atatgaaaat tgtattgaat ggtttctggt tttagataga ctcgattcgt
    50641 taagtttagc cactgaatct ccataggata gaaaatccaa gccagataaa tggtcagaag
    50701 gattgagagg gagaggagaa agagcataga gccccaaaag gtcaatttag ttttcatcaa
    50761 aatcccactc cgcaaggcta gaaaccacat gtgtcggtgc gattggcagg ccagctactt
    50821 cttctgcctt ggtaaaacct gtcgtcacca agagcgttgg aatgccattg tcaatcccag
    50881 cccggatatc agtcaaataa ttgtccccaa ccatgattaa ctcttcacgt tccaaaccta
    50941 agtgctcaac tgccttgtcc ataatgatgg cattgggttt tccgatataa accggcttca
    51001 ctcgtgtcgc tacttcaagc agcgtaatca gtgagccagc acctggcaaa agaccacgtt
    51061 ccgtcgggat gttgaggtca ggattggttc cgataaaatg ggcacccttt tgaatagcaa
    51121 gagttgctgt ggcaaatttt tcatagtcga cttgccaatc cagaccaact accacgtagg
    51181 caggtttttc cttgtcttcc acataaccag ccgccttgat ggcttccttg agtcctgctt
    51241 ctccgacaac atagacggtc ttttcaagcc ccaaatcatt catatagtcg atggttgcca
    51301 aagtcgctgt gtagacagtc gataggggcg tatcgatatt aaaattctga gccaacatct
    51361 ccttaacact ctctggagtg cgggttgtat tgttggttac aaagagatag ggaatgtccc
    51421 gcttttgcaa ttcatgaaca aaagtctctc cagcagggat ttggtctttc cccttataaa
    51481 tggttccgtc taaatcaatt aaatagcctt tatatttcat ctatttctcc ctaagccttt
    51541 tttatttctt gccaagtaat gattgcttgg gcattgataa ccccatcact tgtaatttca
    51601 tgcttgcttt ccagtccagt ccgttcaaca gccgatgtaa tcaccccacc tggtcgaact
    51661 tccttgacat acttgaggtt gattttcttg ggaatatagt gggtcaaaaa atccgctccc
    51721 atgacctcaa aaatccagtc taagtattta ctgttattga catgaccatt catatccaag
    51781 tcgtaaaaac gaacatggta atccttgctg atcgactctt ccaaggactc atacttcggt
    51841 ccacggataa gttttttatc aaaatcagac tggtaaggag ccacaatctc aggttcaaca
    51901 gcatggactt ttcgactgtc gcggtccatg agaacaaagg tcgccatcat atggatgagc
    51961 tcctgccccg cttcattata aatagtaaag cgacggtagc aaaaaagtcg attgtagctc
    52021 aaggcttccg tttcgatggt aatttcttcc gcaaaacgag gcaaacgaac cacctcaata
    52081 tcatattcta cgataatcca gaccagatta tagtcttcca aaatggcctt atcactaact
    52141 cccagttcaa tcgactgcat ccctgaaact tgcagtgaca gcaaaattac atctggaagt
    52201 ttgatatgac cgttcatatc agccatatca aaaggaattt tcattttcat ttgataagtt
    52261 aagcccatga tcctactcca aaataaatcg ttccgctaca gtatctccca aaaagagacc
    52321 tctctttgtc atgcgaacgt ggtcaccctc aatctgcatg aggccttgtt gaaccaaatc
    52381 tctgacaatt tctccataaa gtccagcaaa agactgtcca aatttttcct caaatcgcgc
    52441 catggaaacc ccggatttct tgcggagtcc caagaacatt tcttcttcca tttgctcctt
    52501 ttgactcagg tgatcttctg taatacaagc attgccttcc tcaaccgcac tgagataatg
    52561 acgaatggga ccatgatttt tatagcgtac tccattgaca taaccagatg cccctgcacc
    52621 aataccatag tattcagcat tgtcccagta catgagattg tgacgacttt caaagccggg
    52681 tttggagaaa ttagaaatct cataatgctc aaaacccgct cgctccagct ctgcaatgat
    52741 gtactcaaac atctccgctt ctagttcctc cttaggcaga ggcaatttcc cacgtcgcat
    52801 ccgattcata aagaccgtat ggttttctaa aatcaaacta tacaaactca tgtggggaat
    52861 atccagtcca atggctttag ccacattttc ctttacttgc tccatggtct gaccaggcag
    52921 agcataaatc aaatcaatgg agatgttgtc aaaaccagcc agtttcaggc gatcgatatt
    52981 ttcataaata tccttctcca aatgactgcg cccaatcttt ttcaacatct tatcatcaaa
    53041 ggtctggaca cctagcgaaa cacgattgac agccgaattt ttcaaaacag ctatcttatc
    53101 cgcatccaaa tcgcctggat tggcttcaat ggtcaactct tctaagacag acaagtccaa
    53161 gtttttagtc aagccattca gtaaaacctc cagttgcgga gccgacaggg ctgtcggtgt
    53221 tccaccaccg atataaaggg ttgacaactt ttcaatatca taagaacgaa actcttccag
    53281 cagatgctct aaatagctgt cgactggctg atttttgatg aagacctttg aaaaatcaca
    53341 ataataacaa atctgggtac aaaatgggat gtgcacatag gctgacgttg gttttttctg
    53401 catagtaatt attataccac aaagactaga ttccagataa aaatcaccat ccccagatac
    53461 atagtccgtc cggagatggt gatggtttat tcttctgtta tatcaatcac aatctcttct
    53521 gagtcatcaa gagcttcggc tttttcttgc cattgctcct tgagattatt taattgattt
    53581 tttgatgctt ctgtcgcttg aaaagcatag gatttagctt gagcaagtat actgtccaca
    53641 gtgatttcac ctgactcaac ctgttctttt gttttcagaa caaaatctgt agcctgctcc
    53701 ttaacttctg tcagtttttc acagacttgc tccttggcat actccggatc ttctctcaaa
    53761 tcatctagaa aatcttgagc ctgactgcaa acttgtttgc ccttatcact tgttaaaaac
    53821 aaggcaagag ctgcacctga aacggttcct aaaaggattg aggataattt acccataagg
    53881 attctccttt tttatttttt gaaaaattta cttgcaagac gaagagctga cagacttgca
    53941 ccagtcttga gtgtttttga accagctgat gaagctttct tgctcaagac acgcgcatgg
    54001 tcattgaggt ctgaaacaga tagagataaa tctgcaacag cactgaagag tggatcaatc
    54061 gtagccacct tgacattgat atcatctgcc aagacattga ccttagccaa caactcattg
    54121 gtgtgatgca aggtcacatc cacatctgaa gtcaaggttt taatcgtctt ttctgtttca
    54181 tcgatgacac gaccaagctt ttgtacagta atgatcagat agaccaaaaa gacaatcaaa
    54241 gctagggcaa caagaatata tgcaacttct aacatttagt tttcctcctc tgtaatatag
    54301 taaggggcct tctttcgatt ttgataaata acgatcatta taccgagacc gataaggaca
    54361 actgacagcc attgggacac tcgaaggccg aagaacatga gactatctgt tcgcatacct
    54421 tcgatgacca tacgaccgaa accataccaa atcaagtaaa aggccgtgat atgacctcgt
    54481 ctgagactct tccatttccg tctaaaaatc agaatcaagg caaagccaag cagattccat
    54541 agagactcat aaaggaaagt cggttgacgg tagctcccct caatatacat ctggtcacgg
    54601 ataaagccag gtagataatc cagattatcc actgttgcac cataagcttc ttggttaaag
    54661 aaattacccc aacgccccaa actttgagca atcataacgc taggcgccgc aatatctaga
    54721 aaatcccaag tattgatgag tttacggtca gcaaagatat agagcacaag agccccagtt
    54781 atcaaaccac cgtaaatggc caaaccacca ttccaaatgg caaaaatctc tcctaaattc
    54841 tgactatagt aatcaaatcg gaaaataaca tagtagagac gagctcctaa aatagccaag
    54901 ggaaaggcta ctaagataaa atctaaaata tcgtctggta tgatcttctt tctaggtgct
    54961 tctttcatgg tcaaataaac cgcaagaatc aagcctgtca caatacataa ggcataccaa
    55021 cgaatggcta ggggtcctag ttgaatagca attggatcaa gcattttgca cctcatttcg
    55081 agcgatgaga cttgtcagtc gttcgtcgaa caaacgggtc gcatcaaagc ccatttcctt
    55141 ggcacgataa ttcatggcag ctgcctcaat cacaacagag atattacgac ctgttttaac
    55201 tggaatacga atacgaggaa tggctacgcc agaaacttca agttcctctg cattgtttcc
    55261 aagacgatca aaggtcttat gcgtatcgta attttccaaa tagacagcaa gctgaacctg
    55321 tgaagaatcc ttgacagcac tcgcaccgta gagactcata acatcgataa taccaacccc
    55381 acgaatttca atcaagtgtt tcaaaatttc agctggttca ccccagagag taatctcatc
    55441 cttggcaaag atatcgacac ggtcatctgc taccaaacgg tgaccacgtt tgacaagctc
    55501 aagacctgtc tcgctcttac caattccact atctccctga atcaagacgc ccatcccata
    55561 aatatccatc aagacaccgt gcacactggt acgttctgcc aaacgagaat ccagatagct
    55621 agataactct ccagataaac gactggtagc tgcacggctg gttaaaatag caatcttaca
    55681 ttctctagca gcctttaaca tctcctctgg aaccaccaaa ccacgggcaa caatgactgc
    55741 tggtgtctca gatagaaaca tttttttcaa aacttcataa cggctgttgg aaggcatgct
    55801 gatcagataa gaccactcct tcatccccaa aagttgaatc cgctctggtg tgtagtagtc
    55861 aaaatagcct gtcatttcaa gaccaggtcg cgtaatatcc gctgtattga tttccttttc
    55921 aagcaactct ggttcaccat agacaatatc tagtctaagc ttttcaatca cttcttttac
    55981 taaaaccgac atcatttcct ccttcaaatg agttcttctc tctattatat caaattgtag
    56041 gaggaagttt cagatttttg caggctttgg agtatttatt taaaagaaaa aggactagat
    56101 ttctctagcc tttcattcca attagaattt tttacgttta cgagctactt ctgatttacg
    56161 tttacgtttt acagaaggtt tttcatagaa ttcacgtttg cgtgtttctt gaagagtacc
    56221 agctttagta accgcacgtt tgaaacggcg aagtgcgtcg tcaagagatt cattcttacg
    56281 tactactgtt ttagacattt ttttcactcc cttcaagttc gatatctatt tcattctaca
    56341 cgtaaaagga ataattgtca agcaaaaatg ctgtttaatt ttgatttttt cttccattta
    56401 tacaagagtt gaaagcgttc aatagaacat tgctttttta tttttcgagt aagctaagcg
    56461 cttcagcatc tgcgatgatg gttacatcag ggtgattttg gaggctactt gcaggtaggt
    56521 tctcagtcac tgggccagat actgttccgg caatggcttc tgctttcgac tcaccgtaag
    56581 caaaaagaat aatagacttg gcatccaaaa tgtttttaat ccccattgaa atagcttggg
    56641 ttgggacgtc ttcaatcttg gcaaagaagc gtgcattggc ttcgatagta gactggtcaa
    56701 gttctactag atgcgtttga ctgtcaaatg gagtaccagg ctcattaaag ccgatatgcc
    56761 cattgcgacc gattcccaag atttggaggt caactggatg gtcagccaaa atttggttgt
    56821 agcgttcaac ttcagcttca gcattgtcct taacaccacg aggcaagaaa ctttctttaa
    56881 atggtttttg gttgaacaag ttttcttgca tgaagtaacg ataagactgt ggattgtccc
    56941 catcaaggcc cacatactca tcaaggttga cactggttag atttgaaaaa tcaaggtcac
    57001 tctcaacaat ttccttgtaa aattcaagtg ggctacttcc tgtcgcaagt cctagagttt
    57061 gagctccatt agccaatttt tccttcaaaa tctcaaaagc aacttttcca ccttgaactt
    57121 ggttttcaac tttaataact ttcatctttt catcctccat ttctgtctat atttattata
    57181 tggtatagac caatttttgt caagtgaaaa cgatttaatt tctaaaaaaa gagcgtccaa
    57241 acttgaaacg tgttataatg gataggatta gaacttagaa agaatgaaca gatatatgaa
    57301 tacagctgat tttgatttcc acttgccaga ggaattgatt gcccaaacgc cccttgaaaa
    57361 acgtgatgcc tccaaactcc tcatcgtcaa ccgtgagaca ggagaaatgc aagataaaca
    57421 cttccactct attattaata tgctggaacc tggtgatgcc cttgtcatga acgacacccg
    57481 agttctccct gcccgcctct atggtcaaaa agtggagaca ggaggtcatg tggaacttct
    57541 cctccttaag aacactagtg gagacgagtg ggaagttctg gctaaacctg ccaaacgcct
    57601 caaggtcggt actcgtatca gctttggtga tggccgcctc agcgctgtcg ttacagaaga
    57661 attgacccac gggggacgca ttgtccgctt tgaataccaa ggaattttcc tagaagtctt
    57721 ggaaagtctg ggagaaatgc ctctgccacc ttatatccac gaaaaattag atgaccgtga
    57781 acgttatcaa accgtctacg ccaaggaaag cggctctgct gcagcaccga ctgctggtct
    57841 tcacttcacc aaagaactgc tggcagaaat ccaagctaag ggtgttcatc tagtctatct
    57901 gactctccat gtcggactcg gaacctttag acctgtttct gtggataatc tggacgaaca
    57961 cgaaatgcat tcagagttct atcaactttc tgaggaagct gctgccaccc ttcgctctgt
    58021 caaagaaaat ggtggtcgcg tcatcgctgt cggaaccact tctatccgca ccttggaaac
    58081 tattggttcc aagtttgatg ggcaaatcca agcagattct ggttggacca atatctttat
    58141 caaacctggg tatgagtgga aggtcgtgga tgccttctca accaacttcc atctgccaaa
    58201 atcaactctg gtcatgttgg tttctgcctt tgcaggccgt gaattagtct tagatgccta
    58261 ccaccatgcc atccaagaac actaccgctt cttcagtttt ggtgactcca tgtttattta
    58321 ttgagaaaga atttctctaa atcttctaat accaataaat cgctaagata ttatttcaaa
    58381 gaacatctac aattgaaact ctagctagct gtagaagacg cctagtacat tgaaattaaa
    58441 atgcttcccc ctagcttcga aaatattgcc atagattgcg ttgactctcc aaattgattc
    58501 atctatattt tatttcagct tcctatattt tcttcgctgt ttgtaaatca aaatgcaaga
    58561 cacatgagta gcaccatatt tgttactctt atctgtcctc tcaagagact attatgagtt
    58621 atttcagaat cattcactac tttgaccctg actctcctta gtctcaaaat caaagactta
    58681 tactcttcaa aaatctcttc aaactgcgtc aacgtcacct tggattatat atgtgactga
    58741 cttcgtcagt tctatctaca acctcaaagc agtactttga gcaacctgcg actagttttc
    58801 tagtttgctc tttgattttc attgagtatt aaacaaaaag tgaacaaatc tgaattctaa
    58861 tgtacagaag actaggcttg ttcacttttt tatagtcgct ataagatgac cttatctata
    58921 gctttttata tataattata tataattata tattcagaca tactattatc aattttgtcg
    58981 cagggaggaa tctgttaacg cacccattca ccattatcat tgactctata gccatctata
    59041 cttgtattga ccgctaactc acccgatgca tttacataat accatttacc accaacttgg
    59101 aaccattgat tgactttcat agaaccgttg ctgttgaggt agtaccatga accattaact
    59161 tgtacccaac ctgttgccat ggaaccatca gtattataaa aataccacat accattttct
    59221 tgtttccagt ctgttgttgg agcaactgct ttagctggtt ctactgctac atctgttcct
    59281 tggttagatg taacagatac aggatacgaa ggaatagatg attgctcagg aacaacaact
    59341 ttttcaggtt ctctcgtccc tctccttata cgtcttttta ccatctcttt agtaatttga
    59401 cgagaagtag tttcttcaat tgttccatca cgttcatcta cagtatagat tgtagtaaga
    59461 gtaatttacc aatttctcct acttcttcta cttcttgact tttatcaaga gttgggtcat
    59521 cgagatattc tgtttcgatt ggaatttctt ggacaagaac ttggggcttg gttccttttt
    59581 taacaactct tgtttgagag tcttcttttt gacttaaagt actctcagtt acttgtccac
    59641 tctttccatc tacatcataa gttatcgttg taactgtttt cccattcttt cctagagtaa
    59701 tctcttgctc ctgtcctgca gaaaggtcat tgtctgcttc atatttagta gcacatggaa
    59761 caagaacttc ttcaaccttg cttttagctg gaactttgat aactgtatcc gtggcttgtt
    59821 ttctatcaac agtaacctgt tcggtaacat gaccagtctc tggattaaca tcgtaggtcc
    59881 ttgtcgtagt tacatagcca tcctctccat caattgtaac aggattttca ctacggtctt
    59941 ttgtttcatc tttttcataa cgaattcgcg tacttgaaat tttcttggtt actaccttag
    60001 gtttagtcgc tacttttaca ataatacccc cattgtcagc gtcatcatac tctattccct
    60061 cttctttatc tctagtatca tctctgacat attgaatccc atcagcagca tgaacaaaac
    60121 ttgtattcag attcctccta aaaataaagt tagcccgatt accgcagaac caaaaatctt
    60181 tccgagttta cgtaatgcat agcgcttatt agtattagat tttgccatta catcctactt
    60241 ctagtatagc atcttttcta tcaaacgtta aacaatatac tttatatata aaatagactt
    60301 agaatgatat attgattatt gaactaacac tttaactata tcgtaatcaa tctcatatat
    60361 aaaggattgc agacatctta tctaaataca tgctaatata tttagataca aacattccaa
    60421 cttgataatt ttcactcatc tttcatcatt ccttatacaa ctatgcagta taaatagaat
    60481 agttttctca tcagaatgag actattttaa tattagataa tttgatagaa aaaacatgaa
    60541 taaaattggt tgaatttaat tccctaactc gatagaggat tctattttaa atttaacaac
    60601 agctaggatt acactataaa aagtacatta ccacctgttc ggctggagaa tctagtcgat
    60661 tagctccctc ttagttacaa gcttaaagcg attttttaac taatactaaa ccagattaaa
    60721 gaaggaacta gaacatctgt cttgtactaa tcaatatgct attttaaagt ttcaaataaa
    60781 cttggaatgc taattattat atttacaata aatagttgac ttcgatagaa acagaaaata
    60841 gaattcaaca ttcttcccta cttataccat aataaataag atccgcaaga tagccttttc
    60901 tctctacacc attaacaatg gtttgtagat aggacattcc agccttttcc atgacacgac
    60961 ctgaagctgg gttgagactg gcataacgtg ctctgacctt ttgaaaacct gcttgagtaa
    61021 aacaaaagtc caagatagct ttcaaagtct ctgtcatcat accatttccc cagtaagcct
    61081 tgcctaacac atagccaatt tcacagctta aatcagcctc gtctatctta acgatgctga
    61141 tatctcctat cacttgctct gggttttctt ttagacaaat ggcccattta taatagttga
    61201 gattagtata ggaagcaacc caattgcgaa tcgagtttcg agtgatttcg atatcaggat
    61261 ggggatccca ggtaacatag gtcagattct cagcagatga agcccaattt tgaaacatgg
    61321 cttctgcatc actctccaca aatcttctta aaatcaaacg ttctgtctgt aatatttgcg
    61381 taccgataga tttcatgatg ctacctcact tccttatttc tatgctcgta gtaaaaaggc
    61441 tcaactcagt aacagctaga aaacgagttt gtcttctaat ttcttgacgc agtcgctgcc
    61501 tggtttgaaa tgcgctctag caagcttttt caaacctagt catcgttgca ggggtaagac
    61561 gatgaaatcg aactcttcga gttaccgaat ctgcctcatt ttcttatttc taaactcggg
    61621 gttcaagatc ccccagacct tctctcactt tcttatttca agatgagagg ctgaaaacct
    61681 ccagtggagg tttttcttgc tttttaattt cagggcaaga agctaaaaag gtccccggac
    61741 cttcttcgct ttctcatttc taggctcagg gtaaaaacct ccaatggagg tttttactcc
    61801 caaaagtcat caaatacagt gatgggtaag tggcgtttgt gttggccttt gtgccaccag
    61861 ttttcaatgg tcgcttgagc ttctgggctg attgttttgc cttctaggta gtcgtcaatc
    61921 tctgcgtagg tgactccaag tgcgacttcg tcagctaggc ctggtttatc ttcttctagg
    61981 tctgccgttg ggattttttc ataaagggct ggctctgcgc caagtttctg caagagctgt
    62041 tttccttggc gtttattgag gcggtaaaga gggagaatat ccgcaccgcc gtcaccaaac
    62101 ttggtaaaga aacctgtgat attttccgcg gcgtggtctg ttccaatgac cgctccgcta
    62161 tgggaaccag caagggcata ctgagcaatc atacggcaac gtgccttgat attccccttg
    62221 ttgaagtctg aaacaggact acctgtcgct tcaactgcag ctgtcatggc atcagctgat
    62281 tccttgatat tcacaaccaa gctgacatct ggctggatga aggctagggc tttttgagca
    62341 tctgcttcat cagcttgcac tccgtatggc aggcggacag cgataaattt gtagctgtcg
    62401 tctcccgttt cagctcgcag ttcttccata gctaattgcg ccaaacgccc tgccaaggtt
    62461 gagtcttgtc ccccagaaat ccctagtaca aaggttttta ggaagggatg ttttttcaga
    62521 tatcttttta agaaatcaat agaacgacgg atttcttcct gggcatcaat cactggtttg
    62581 acacccagct cttggataat cgtttcttgc aaactcattc ttcttctcct tcaccaaggg
    62641 cttccttgcg catcttatca atcaagtcca tcttatcttg ccatacatca cgcgccaaat
    62701 ccactggata gtgctgcgga ttgagcacac gcttatactc atcccacaac ttgtcaaatt
    62761 ccttacgggc ataatcctga atgtcagtca aactaggcaa gttgtaaact aatattcctt
    62821 ctttgaagat atccaccaag agaggaacgg catcaaaatt acgaaccgtc ttcttgatgt
    62881 atgtataggt cggatggaac atcttgattt ctgtcatgtc gctaatatcc acaccatcat
    62941 aagtgatata gtcgccttct gacttgcctt tttcacgact ggtaatgcgc cacacctgct
    63001 tcttacctgg cgtagagact ttttccgcat tattagacag cttaatcgta ttgcgcatct
    63061 gaccagtttc atcttcgatt gcaacaatct tgtaaactgc accaagagct ggctggtcat
    63121 aagctgtaat cagcttggta cccacgcccc agacatcaat cttggccttt tgcatcttga
    63181 gattgaggat ggtattttca tctagatcat tagaagcata aatcttagcc tctgtaaatc
    63241 cagcctcatc cagttgctga cggactttct tagaaatgta ggcaatatcc ccagagtcaa
    63301 tccgcacacc cataaagtta atctgatcac ccagctcacg cgccacctga atggcagctg
    63361 gtacaccgat gcgaagggtg tcataggtat ccacaagaaa gacacaattt ttgtgggtcg
    63421 cagcgtaagc cttgaaagct tcatagtcat tgccataaac ctgtaccaag gcatgggcat
    63481 gggttcccaa aacaggaatg tcaaagagct tacccgcacg cacgttgctg gttccattgg
    63541 cgccaccaat cacagctgcg cgtgttcccc agatggccgc atccatttct tgagcccgac
    63601 gtgtcccaaa ctccatcaag ggttcatctt cgataaccga acgaatacga gctgccttcg
    63661 tcgccaccaa ggtctggtag ttgacgatgt tcaaaagagc cgtttcgacc aactgacatt
    63721 gggctagagg tccttccacc tgcacaatcg gttcattagc aaaaaccaaa tccccttctt
    63781 gggcagaacg aacggtcaac tccaacttga aattgcgaag gtaatccaag aacgccccat
    63841 gataaccaag cgactccaaa taggctatat cactatctga aaaacgcaag tcttcaagat
    63901 agttcacaat tctttccaaa cctgcaaaaa ccgcatagcc gttcttaaaa ggctgttggc
    63961 ggaaatacac ctcaaagacc gccttcttat tgtgaatccc ttggtcaaag taaacctgca
    64021 tcatgttgat ctggtacaag tccgtgtgca atgtcaaact atcatctgga tacatacttt
    64081 tcctacttcc ttagctagaa acccatgaaa attttcaaga actttcatgt attccaataa
    64141 attagtacta ttatatcaca ttttagctgg attgagaaaa gagtaacaag ctattctcca
    64201 ctctccaatt catccatatc ttgttcaaat tttttctgag cccattcgcc atagctctta
    64261 agaccaagat tgccaataaa gacccacgga aggtaaatga cataagtaat gacccaagca
    64321 gacaggtatt taaaattcaa aggattgtgc tgataaattt ctatgttgaa ttgataattc
    64381 tgcaacatca aaagagccgt aatagccaag gttaggaaaa aacaacccaa aatcgtaaaa
    64441 tgaaaacgac tatagtaggt cactcccaga taacgggcac ggttaaaaaa gtaaaatgtc
    64501 cctatgatga taacgattag cagcatatta gaattaaaaa ggcttggtgc taatactgaa
    64561 atgatataag ataggagcga caaagcgatg cagatataga aactttcaga gcccgcttta
    64621 ttgatcagtt gttcttctct ttcgtctagt aattgataat aataaaatct atttttcatc
    64681 ttcttcctcc caaaatagtt ggtctagggt tttccctaaa catctgcaaa tagactggca
    64741 gagcgagaga ctgggattgt attttcccgc ctctatcaaa ccaatagtct ggcgtgtcac
    64801 cccgacagcc tctgccagtt gaccttgtgt taaatcacgc tctacccgag ctaattttaa
    64861 ttttaaattt ttagccacct tcgtcctcct tatagtttta atactcatct actctttaaa
    64921 aatccaaact aacacaagct gtcagctatt tattataacc ccattaattt gcactccagt
    64981 attatcttca gccgaaaatc agtattttag gttgtttgaa ataaacttcc tagtttactc
    65041 ttttattttt atttttattt agcattagct ttagtaggat cttttaaacg agtttttatt
    65101 gcttatattt cttgtttagt ttagttggtt tcatatcact attatataat gcttttggaa
    65161 atgagcctag tataagtcaa aaacgtgttg aatagtgaaa gcaggagcat accaatatga
    65221 ctgatttttt actgtatttt aggtatgcaa aataatacta aatgaaacta aaatgaatac
    65281 ttcttgcttt tcttgagagt gaaaaagtac aataaaatga ttgtagtgat tgccacaaga
    65341 tactgactaa tagacatcgt atttgaagcc acaaatacag gtaaagaata aaaaggaaga
    65401 agttcaattg ctttgataaa caaatcatta ctagtattca tcatcgtatt taatatatta
    65461 gggataaaga gtagtaaagc tactaaaata ccaagccact tttcaatttg tataaataga
    65521 aaatgtaaga taatagaaaa taaaacagga ctaacaaaat tgtattgact acaatagcta
    65581 ctataaaatc taatcctaaa tcacctggaa tacccaattt acttactatg actagtaaca
    65641 caatgccatt caaagcataa ataatggaag ctgagatggc atatagaaaa ttagacaaga
    65701 cgtaaatcat ccgattcttc tgttgattat aaaacaaact taccgtattg tgggaaaaat
    65761 ctctactaat gactcgatta gcatgtataa cagccattaa cataccgagc atagcataaa
    65821 agtttgaaat atgcttaata ccaagcgatg tcccttaagt ctttagaata aagaatgtaa
    65881 gcaatatcgg cggtataaac gagataagca aactgagata tattacgcct gatgaatata
    65941 aatttcttat attttcctta agaaaattca atttatttaa tttcatgatt ataaccttcc
    66001 tttattttga acgatttagg taaatatctt taagcgtctc ttttttagtt tcaaaatcaa
    66061 ctactttaat agagttttcg ttaaaaaatt taaaaagctc actactttga atattcccag
    66121 acatagtaat tctcaatccc tcttcctgaa caatatcccc aaattcttgt ttggtaatga
    66181 aaatgtctct atctgtagct gatgaaaaag ctatctcaaa caagaaatta tgactatctt
    66241 ttcctacttt ttgaaatgtc aaaagcccgt tctccaagaa aagaactctc tcacaaattt
    66301 cttcaatgtc ttctaattta tgactcgata ttaaaattcc cacgttttca tttaaagcta
    66361 atttttttag aaccgctaaa actatttgtg atgattcaat atctaaacca ttagtcggtt
    66421 catctaaaat caatatatca ggttccgtaa cgagagttag aagcaaagct aatttttgtt
    66481 ttgtacccaa agaataggtc tttacttttt tattaataga ctgagtcaaa tctaactctt
    66541 ggatcaaact tctaaatctt tcttgattgt agtcaacacc atataaattt gacaaatatt
    66601 ttaaattctc taaacctgtt ttagataaaa ataattttgg ttcttcgatt aaatacccaa
    66661 cattatcact gcttataata ttacctgaag tcggttgatt attttgaaca agaattttca
    66721 tcaacgtact cttaccaact ccatttctcc ctactagacc aacaatttca cccttgttaa
    66781 gtgcaaaatt tatatctttg agaatgattg aatgaccata atgcttactt acatttttat
    66841 tcctacatta atattcatgg tttactcttt gattcttatt gagtttaaaa agttgcgcct
    66901 ctttttaaca atattatatc atatatctaa cttgatgcaa tatataaatg tcattttgta
    66961 aaattttatt aacaaaaaac tctctacaac aaaataatag agagttttct gcttattaat
    67021 ttttttcaaa atatctaaga catcgcttct ttgtttaatt tgataggctt tgatacctaa
    67081 gctccgactt tatcacttaa aaaataaaaa agacagctaa tctcttgcgc atcaagggat
    67141 ttcgccattc tttaatctcg tttaagtgtt gtatatggag ctttgcataa ttttttaaaa
    67201 ctaaacaact acattaagca cgaactgtga cgctggttcc atcttcctta taaagattga
    67261 taagcccctc tttaagagct cgaaccatgt ctcctgattg aacgggttgt gggactttaa
    67321 tagtcaatag ttccattgga tttggagcgc ggtcgatttt attgcctttg gcatcatgca
    67381 aatcttcaat ataggtttca aaatgacgga aacctggacc ataaaactca acttg
//
LOCUS       DAVAZV010000004        64201 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVAZV010000004 DAVAZV010000000
VERSION     DAVAZV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 64201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 64201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..64201
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.004"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(177..524)
                     /locus_tag="VQT46_000227"
     CDS             complement(177..524)
                     /locus_tag="VQT46_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2370333.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(635..2410)
                     /gene="spxB"
                     /locus_tag="VQT46_000228"
     CDS             complement(635..2410)
                     /gene="spxB"
                     /locus_tag="VQT46_000228"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET2370334.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAISKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(2617..4860)
                     /locus_tag="VQT46_000229"
     CDS             complement(2617..4860)
                     /locus_tag="VQT46_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2370335.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQSLHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(4870..5241)
                     /locus_tag="VQT46_000230"
     CDS             complement(4870..5241)
                     /locus_tag="VQT46_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET2370336.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(5252..5647)
                     /locus_tag="VQT46_000231"
     CDS             complement(5252..5647)
                     /locus_tag="VQT46_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET2370337.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      5831..5929
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6013..6804
                     /gene="thiD"
                     /locus_tag="VQT46_000232"
     CDS             6013..6804
                     /gene="thiD"
                     /locus_tag="VQT46_000232"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2370338.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7013..7645)
                     /locus_tag="VQT46_000233"
     CDS             complement(7013..7645)
                     /locus_tag="VQT46_000233"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2370339.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(7638..8441)
                     /locus_tag="VQT46_000234"
     CDS             complement(7638..8441)
                     /locus_tag="VQT46_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2370340.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(8441..8965)
                     /gene="thiW"
                     /locus_tag="VQT46_000235"
     CDS             complement(8441..8965)
                     /gene="thiW"
                     /locus_tag="VQT46_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET2370341.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERID"
     gene            complement(8970..9662)
                     /gene="tenA"
                     /locus_tag="VQT46_000236"
     CDS             complement(8970..9662)
                     /gene="tenA"
                     /locus_tag="VQT46_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET2370342.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(9673..10323)
                     /locus_tag="VQT46_000237"
     CDS             complement(9673..10323)
                     /locus_tag="VQT46_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET2370343.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAIFPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAYGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(10325..11710)
                     /locus_tag="VQT46_000238"
     CDS             complement(10325..11710)
                     /locus_tag="VQT46_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370344.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIVERVQTVGILLQNPNHQFTMESLFEELVFTMENI
                     GYHLQEIDSKIAEVVQQCRCKDILHRLIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELVYDGKTVILCDHDLSDYKAYIDHMVELRDGKLREVFQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGSITWKGSVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(11711..12271)
                     /locus_tag="VQT46_000239"
     CDS             complement(11711..12271)
                     /locus_tag="VQT46_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2370345.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGFVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(12533..12621)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(12830..13459)
                     /locus_tag="VQT46_000240"
     CDS             complement(12830..13459)
                     /locus_tag="VQT46_000240"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET2370346.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(13461..14243)
                     /gene="thiM"
                     /locus_tag="VQT46_000241"
     CDS             complement(13461..14243)
                     /gene="thiM"
                     /locus_tag="VQT46_000241"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET2370347.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVMIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(14486..15154)
                     /locus_tag="VQT46_000242"
     CDS             complement(14486..15154)
                     /locus_tag="VQT46_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET2370348.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVDKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(15369..15457)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15711..16847)
                     /gene="lctO"
                     /locus_tag="VQT46_000243"
     CDS             complement(15711..16847)
                     /gene="lctO"
                     /locus_tag="VQT46_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET2370349.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(17472..18962)
                     /gene="lysS"
                     /locus_tag="VQT46_000244"
     CDS             complement(17472..18962)
                     /gene="lysS"
                     /locus_tag="VQT46_000244"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET2370350.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLITKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLEEAKTIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19090..19236)
                     /locus_tag="VQT46_000245"
     CDS             complement(19090..19236)
                     /locus_tag="VQT46_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET2370351.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAGDTF
                     TSFQ"
     gene            19462..20130
                     /locus_tag="VQT46_000246"
     CDS             19462..20130
                     /locus_tag="VQT46_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2370352.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRILV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFYYVVLPQATAVALPSFSANVIFLIKETSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRLRHAGFGNPST
                     LSRK"
     gene            20090..20767
                     /locus_tag="VQT46_000247"
     CDS             20090..20767
                     /locus_tag="VQT46_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2370353.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIEISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLDFTRIMPQLVLLFIVYFGLARNFNINISGETSAIIVFTLW
                     GAAEMGDLVRGAITSLPKHQFESGQALGLTNVQLYYHIIIPQVLRRLLPQAINLVTRM
                     IKTTSLVVLIGVVEVTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTH
                     LEKHWRN"
     gene            20768..21525
                     /locus_tag="VQT46_000248"
                     /pseudo
     CDS             20768..21525
                     /locus_tag="VQT46_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21537..22398
                     /locus_tag="VQT46_000249"
                     /pseudo
     CDS             21537..22398
                     /locus_tag="VQT46_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765255.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
     gene            complement(22478..23125)
                     /locus_tag="VQT46_000250"
     CDS             complement(22478..23125)
                     /locus_tag="VQT46_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370354.1"
                     /translation="MNEIIILKNIELKLKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23122..23820)
                     /locus_tag="VQT46_000251"
     CDS             complement(23122..23820)
                     /locus_tag="VQT46_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370355.1"
                     /translation="MGKLSSHMWRLNKIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDVGGDLFLQLLFLVFLFQ
                     SIFYFTRQKRRFIE"
     gene            complement(23830..24582)
                     /locus_tag="VQT46_000252"
     CDS             complement(23830..24582)
                     /locus_tag="VQT46_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370356.1"
                     /translation="MKQFVQFYKKDFLSVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLNNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(24582..25346)
                     /locus_tag="VQT46_000253"
     CDS             complement(24582..25346)
                     /locus_tag="VQT46_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370357.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(25442..25845)
                     /locus_tag="VQT46_000254"
                     /pseudo
     CDS             complement(25442..25845)
                     /locus_tag="VQT46_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26025..26657)
                     /locus_tag="VQT46_000255"
     CDS             complement(26025..26657)
                     /locus_tag="VQT46_000255"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET2370358.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYRELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(26691..27392)
                     /gene="pyrF"
                     /locus_tag="VQT46_000256"
     CDS             complement(26691..27392)
                     /gene="pyrF"
                     /locus_tag="VQT46_000256"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET2370359.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQNWN"
     gene            27713..27805
                     /locus_tag="VQT46_000257"
                     /pseudo
     CDS             27713..27805
                     /locus_tag="VQT46_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011516271.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(28127..28840)
                     /locus_tag="VQT46_000258"
     CDS             complement(28127..28840)
                     /locus_tag="VQT46_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370360.1"
                     /translation="MLKRFLALVWLRCQIILSNKSILLQVLVPFAFTYFYKYLMETQG
                     KVNDQQALVLLMMCLPFSLALAVGSPITIILSEEKEKYNLQTLLLSGVKGSEYILSTM
                     FLPFLLTFVIMGTTPLILGVTIVHTFNYITIVLLTSLSIILFYLLIGLTAKSQVVAQV
                     ISLPAMILVAFLPMLSGLDKTVAKITDYSFMGLFTKFFTKWEGFSWNKTLIPNLTLLI
                     WIVLLLTLITITIRKKKIS"
     gene            complement(28833..29528)
                     /locus_tag="VQT46_000259"
     CDS             complement(28833..29528)
                     /locus_tag="VQT46_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370361.1"
                     /translation="MTGQFLADKGQSIILGQKSQNLTSGELKRIGLVSDTSGFYEKMS
                     LYNNLLFYSKFYNISKSRVDNLLKRVGLYDSRKMVAGKLSTGMRQRMLLARALINKPA
                     VLFLDEPTSGLDPTTSRTIHELILELKTAGTTIFLTTHDMNEATLLCDYVALLNKGKL
                     VEQGAPSELIQRYNKDKKIKVTDYNGNQITFDFTSLEQVSQADLENIFSIHSCEPTLE
                     DIFITLTGGKLNA"
     gene            complement(29868..31200)
                     /locus_tag="VQT46_000260"
                     /pseudo
     CDS             complement(29868..31200)
                     /locus_tag="VQT46_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812020.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
     gene            complement(31184..31982)
                     /locus_tag="VQT46_000261"
                     /pseudo
     CDS             complement(31184..31982)
                     /locus_tag="VQT46_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824573.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M50 family protein"
     gene            complement(32772..33971)
                     /gene="divIB"
                     /locus_tag="VQT46_000262"
     CDS             complement(32772..33971)
                     /gene="divIB"
                     /locus_tag="VQT46_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET2370362.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(33981..35039)
                     /locus_tag="VQT46_000263"
     CDS             complement(33981..35039)
                     /locus_tag="VQT46_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET2370363.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VAKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(35041..36393)
                     /locus_tag="VQT46_000264"
     CDS             complement(35041..36393)
                     /locus_tag="VQT46_000264"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET2370364.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(36497..37138)
                     /locus_tag="VQT46_000265"
     CDS             complement(36497..37138)
                     /locus_tag="VQT46_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370365.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(37140..39161)
                     /locus_tag="VQT46_000266"
     CDS             complement(37140..39161)
                     /locus_tag="VQT46_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2370366.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFTYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLSYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLMSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDTENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNLLYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            complement(39232..39531)
                     /locus_tag="VQT46_000267"
     CDS             complement(39232..39531)
                     /locus_tag="VQT46_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2370367.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(39897..40151)
                     /locus_tag="VQT46_000268"
     CDS             complement(39897..40151)
                     /locus_tag="VQT46_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET2370368.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(40171..42012)
                     /gene="typA"
                     /locus_tag="VQT46_000269"
     CDS             complement(40171..42012)
                     /gene="typA"
                     /locus_tag="VQT46_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET2370369.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            42174..42899
                     /locus_tag="VQT46_000270"
     CDS             42174..42899
                     /locus_tag="VQT46_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase"
                     /protein_id="HET2370370.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVQVNELLTPDHIQAFQKGIVFLDGTVC
                     KPAKLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     ESNYRPLNQKELQIIKNYLEMSR"
     gene            complement(42939..43166)
                     /locus_tag="VQT46_000271"
     CDS             complement(42939..43166)
                     /locus_tag="VQT46_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370371.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(43255..43635)
                     /locus_tag="VQT46_000272"
     CDS             complement(43255..43635)
                     /locus_tag="VQT46_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2370372.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(43635..43904)
                     /locus_tag="VQT46_000273"
     CDS             complement(43635..43904)
                     /locus_tag="VQT46_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET2370373.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            43968..44876
                     /locus_tag="VQT46_000274"
     CDS             43968..44876
                     /locus_tag="VQT46_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2370374.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(44930..45685)
                     /locus_tag="VQT46_000275"
     CDS             complement(44930..45685)
                     /locus_tag="VQT46_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2370375.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(45706..46635)
                     /locus_tag="VQT46_000276"
     CDS             complement(45706..46635)
                     /locus_tag="VQT46_000276"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET2370376.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(46650..47273)
                     /locus_tag="VQT46_000277"
     CDS             complement(46650..47273)
                     /locus_tag="VQT46_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET2370377.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(47266..48504)
                     /gene="hflX"
                     /locus_tag="VQT46_000278"
     CDS             complement(47266..48504)
                     /gene="hflX"
                     /locus_tag="VQT46_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET2370378.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(48497..49381)
                     /gene="miaA"
                     /locus_tag="VQT46_000279"
     CDS             complement(48497..49381)
                     /gene="miaA"
                     /locus_tag="VQT46_000279"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET2370379.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTLEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            49502..49672
                     /locus_tag="VQT46_000280"
     CDS             49502..49672
                     /locus_tag="VQT46_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET2370380.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(49720..50559)
                     /locus_tag="VQT46_000281"
     CDS             complement(49720..50559)
                     /locus_tag="VQT46_000281"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET2370381.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPIITLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(50656..51615)
                     /locus_tag="VQT46_000282"
     CDS             complement(50656..51615)
                     /locus_tag="VQT46_000282"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET2370382.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(51742..52740)
                     /locus_tag="VQT46_000283"
     CDS             complement(51742..52740)
                     /locus_tag="VQT46_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2370383.1"
                     /translation="MNKRLFLKMSLVTLPILALFSQPVLAEENIHFSSCKEAWANGYS
                     DLHEGEPGYSAKLDRDHDGVACELKNAPKGAFKAKQAATTQTDTTSSTASGWVKQDGS
                     WYYFDGNGNLVKNAWQGNYYLKADGKMAQSEWIYDSSYQAWYYLKSDGSYAKNAWQGA
                     YYLKSNGKMAQGEWVYDSSYQAWYYLKSDGSYARNAWQGNYYLKSDGKMAKGEWVYDA
                     TYQAWYYLTSDGSYAYSTWQGNYYLKSDGKMAVNEWVDGGRYYVGADGVWKEGQASTA
                     SSSNDSNSEYSAALGKAKSYNSLFHMSKKRMYRQLTSDFDKFSNDAAQYAIDHLDG"
     gene            complement(52790..53407)
                     /locus_tag="VQT46_000284"
     CDS             complement(52790..53407)
                     /locus_tag="VQT46_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2370384.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            complement(53408..55129)
                     /gene="pabB"
                     /locus_tag="VQT46_000285"
     CDS             complement(53408..55129)
                     /gene="pabB"
                     /locus_tag="VQT46_000285"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET2370385.1"
                     /translation="MHRKTVIDFRTLGERYTFAQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDSVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(55198..60885)
                     /locus_tag="VQT46_000286"
     CDS             complement(55198..60885)
                     /locus_tag="VQT46_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2370386.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEETPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKSEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQEDNPKEDRGAEETPKQEESTPDTKAE
                     ETVEPKEETKTAKGTQEEDYVGEALVPEQLPEYKVTEGTLVEESTTELDYKTETTEDP
                     TKYTDEETVLRNGEKGSQVTKTTYKTIGGVKTDQVLSTSTEVTKEPVNQQVIRGTKPI
                     EGTTVETREEIIPFETKEQEDDTLKRGTRQVTQEGVNDKKQITETYKTIRGEKTSDAP
                     TITETVIEKPQDKIIKNGTKELEKPTLEWAKTDKDVLKKSATASYTLTKPAGVEIKSI
                     KVALKDNTGTVVKEVTVEENNLQATLDNLKYYQGYTLSTTMVYDRGNGEETEILEDKE
                     VQLDLKKVEIKDIKETRLMKVDENGNETDSSLLETVPENLTSYYLKITTNHNKVTRLA
                     ITNIEEVTEEETSLFKVTASAPDLIQRDSNNSLSQTYTYYIEKPKASQNNVYYNFKDL
                     VDAMQKNPNGEFKLGSDLNATNVPTPSKSYVTGKFTGHLTSVDGKHFSIHNTARPLFD
                     RVEGGSIKNINLINVNINMPWANQLASLAQTVKNATVENIKVTGTIVGNNNVAGILDK
                     LDDAGIMTNVAFIGKVQSVGDKGWNLAGIASEIYRGNLNKAYADVELKGLNTRAGAIV
                     GHLAHDFNPRDVGAWSNVRNSVAKGTIDVARGDVGGLIGKDWPWGTIDNNISLVNVKR
                     GDIFFGSNDMDDEFVSNWIKPNNATVIGVSSGDKTHKQSSKIKEISQVEADKKIKDMG
                     ITADTFEVTEHLVDKLNRRILRDEEYKTIQDYNANRELVYRNVEKLQPFYNKEWIVNQ
                     GNKLTTDSPLMNKEVLSVTAMKGNDFITDLTDADHIMVHYADKTKDIFTISPKDSQVK
                     QVKEYSVAELGEVVYTPNMVVKDRADLISAIEGILSPIELQSDPIYQRLGRTGDNRVN
                     AIKNLYLEESFKEVKDHLNTFVTKLVENEDHQLNTDEAAKRALIKKIEDNKAAVLLGL
                     TYLNRYYGVKFDNFNIKELMLFKPDFYGKNVSVLDRLIEIGSKEDYIKGSRTQESFRE
                     VVAKNTLSGNLHDFLTYNMKLFTNETDINVWFKKAIENNAYVVEQPSTNPAFANKKYR
                     LYEGLNNGQHGRMILSLLNLKDAHLFMISTYNTISFSSFEKYGKDTEEKRESFKSEIN
                     KRAKEQVNYLDFWSRLATDNVRDKLLKSQNVVPTPVWDNHGAPGGWPDRFGHRKDKPD
                     YAPIREFFGRIDKYHDYKYGYGAYAYIFADPQPMDAVYFVMSDLISEYGTSAFTHETT
                     HVNDRMAYLGGHRHRQGTDLEAFAQGMLQTPAEHGHQGEYGALGLNMAFERSNDGNQW
                     YNPDPTKLQTRDQIDHYMKNYNEAMMMLDYAEAEAVLPKVKGDNSKWFKKIDRETRRP
                     MDRNKLSGPHQWDKVRDLIDAEKTTNLETIDDLVNNNFMTIHGNPGNKVFHPEDFGTA
                     YVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYEHGFIDYVSSKHQGAANKEN
                     NGLLGDDFIIKKVSNNQFSNLEDWKKQWYGEVLTKSKKGFAPIEINGTQISTYEQLKT
                     MFDEAVTKDLTELNDSSIKDKYRNTVVLKSKVFKALLKNTDGFSGDLFTAPQA"
     gene            complement(60907..61470)
                     /locus_tag="VQT46_000287"
     CDS             complement(60907..61470)
                     /locus_tag="VQT46_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET2370387.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(61586..63277)
                     /locus_tag="VQT46_000288"
     CDS             complement(61586..63277)
                     /locus_tag="VQT46_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2370388.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(63274..64011)
                     /locus_tag="VQT46_000289"
     CDS             complement(63274..64011)
                     /locus_tag="VQT46_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2370389.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        19327 a        13922 c        11331 g        19621 t
ORIGIN      
        1 gaggtgataa agtccatcgt taatcggaga tggaatagaa tgctttttga aagcagatga
       61 gtattatatg caatttcttt atataaaaag accggattgc tccgatcttt caatagttca
      121 tattctcaat ttctatttta aaaatagcta aggttaacgt caaatgacta cgcgacctat
      181 ttcatacgat aaaaatcaag cactagacca gcaggtcctt gaactaataa ggactctgtt
      241 ccccaatcgg ttacagttgg tccgtgtaaa acctttatac caagctcatt caaccgtttg
      301 tagttctggt ctacatcctc aacctcgata tgaataatga ttcctgactg aaagttttcc
      361 aaaggaacca aatgattttg tgacaacata aggcagtgac taccaatcgt aaactgagca
      421 aaaccatcat cagcataatc tgccttttta tccaaaatat gctccaagtc agcacagact
      481 tggggaacat ttgaaacgat aatatctaat tgatttaaat tcatttactc tcctccataa
      541 aaagaccgaa ttgctccgat cttttaaagt tctgctctat gaaaatcaaa gaataaagtc
      601 tacaagtttc atatttgatt ttcggcgaga ggaattattt aattgcgcgt gattgcaatc
      661 cttcttcttc caagaagaga cggaatggta cgagttcttc tgcttcgtat ttttccttga
      721 aggctttgat agcttcttct gagtgaagtt ttggatccaa ttcaagtact tctactggaa
      781 gtggacggtg ttgagtgatg cgagcatcga tgacaacagt tttaccttct ttgttcaatt
      841 taacagcttc tgcaacaact gcatcgatgt cttcgatacg gtcaactgtg aatccaacag
      901 ctccttgagc ttccgcaatt ttagcgtagt cagcgtttgt gaagtctaca ccaaacaagt
      961 gtttgtttgt atcttcgtat ttgttcttga tgaagccgta ctcagcattt gagaagacaa
     1021 ggttgataac tggaaggtcg tattgaacgt ttgtgataac gtctgggtag cacatgttga
     1081 atgctccatc acccatgatg ttccatactt ggcgatctgg attgtctttc ttagcagcga
     1141 taccaccagg aagggcaata cccattgtcg caaagagcgg agatgtacgc cacatattct
     1201 taggtgtcat gtgaaggtga cgagtagatg tttgagtagt gttacctacg tcgattgagt
     1261 agatagcgtc ttgatcagca tgtttgttga ttgcattgta aacttgatac aattgcaatt
     1321 caccctcagt tttaccttcg agtttgttca tgtaatcacg ccagttttgg ttgttcttaa
     1381 cgtttgcacg ccaccatgga gttgattcaa ctgggtttac tttgtcaagg atagctttag
     1441 ctgcttgacc agcatcacca aggattgaag cgtcaagggc atgacgttta ccaagtttgt
     1501 aagggtcgat atcgacttgg atgaattttt cagtgttctt gaatgcttcg taaacttcag
     1561 caaatgggaa gtttgaacca aggaaaagaa ctgtgtctgc ttcaaagacc acttcgttgg
     1621 ctggtttcca accaacacgg taagcagaac ctgtcaaacc ttcatagttc cattcgaaag
     1681 cttcaaagtt tttaccagtt gtgatgattg gtgctttgat tttacgtgac aattcagtaa
     1741 tcacttcacc agctttaaca ccaccaaatc cagcatagat aactgggcgt tcagcattgt
     1801 tcaagatttc aacagctttg tcgatttcaa cttcgttcaa agcaggagcg atgaatgagc
     1861 gttcgtatga acctgaaccg tagtatgagt tttcgtcgat ttcttggaaa ccgaagttta
     1921 ctggaatttc aacaacagct ggaccttttt tagaaattgc agcacggcag gcttcgtcaa
     1981 ttacttttgg caattgctca gcgtaagcta cacgtttgtt gtaaacagcg ataccgttgt
     2041 acattgggtt ttggttaagc tcttggaaag catccatgtt caattcgtta actggacgtg
     2101 atccaaggat cgctaggaat ggagtgttat ccatagctgc atcgtaaaca ccgttaatca
     2161 agtgagtcgc acctggacca cctgaaccaa ctgcaacccc gattgagccg ccgaatttag
     2221 cttgcataac cgctgcaaga gcacctgtct cttcgtggcg aacttgtaag aagcggatat
     2281 ctttgtcttc agccaaagcg tccatcaatg agctgagtgt tcctgatggg ataccgtaga
     2341 ttgtatctac gccccatgtt ttcaatacgt taagcattgc tgcagatgca gtaattttcc
     2401 cttgagtcat aatgataact ctccttcaat ttttttagat ttggagaata cgattacata
     2461 gaattggaaa cgttctccaa atttttacta ttccactgta tcatatttat gctgactttt
     2521 ctaaaaatct gctcaaaact ctctattctc tattctaata cagttttgaa agttctgtca
     2581 tttctgtttt ataacaaaga aatctagtca ttacttttag tctattttac taaaatttaa
     2641 cagaagggaa ctggtcagaa cagatacaga actaaaggcc atggctagac ctgccaattc
     2701 tgggttgaga gccagtccaa cacctgaaaa gactcctgct gcaatcggaa ttccgacaac
     2761 attgtagata aaagcccaga aaagattgag tagaattcga tgaaaggttt tcttactcat
     2821 atcaaaggca cgaaccactc ctaaaagatt attggttgtc aacaccaaat ctgctgactc
     2881 gatggcgata tctgttccag ctcccatagc aatccccaca tctgctacac taagggcagg
     2941 agcgtcattg ataccgtccc caacaaaggc tactttccct gactgttgca gtttatggat
     3001 ttcatgggct ttttcttctg gcaagacgcc tgcaatgacc tcttcaattc cgatttgatc
     3061 tgcaatagca cgcgccacac cagcattgtc tcctgtcagc atgactgttc ggagaccacg
     3121 tttttttagc tgactgatgg ctagcttagc attttcctta ggaatatctt gcaaagcaag
     3181 caagcctttg atttcattgt caacagctaa gaacacaact gtcttagctt ctttttctag
     3241 ttcttctagt ttatcttgat aagtattaga aatatccata ccatccagca ttttagcatt
     3301 tccaagtaaa acttgttttc cattgattcg ccctgaaaca cctttcccgt gcaaggactg
     3361 aaaattttca acagtttgaa actcaagtcc agcttcactc gctcgcttaa cgatagcctc
     3421 agccagtggg tgttgagaag catcttccaa ggaggctgcc aatccaaaca cttctacttc
     3481 gtcgccgatg atatctgtta ccacaggttt cccttccgtc aaagtcccgg tcttatcaaa
     3541 gacaagagtt tgaactttct ggatttcctg taagacagtt ccatttttga ggagaacccc
     3601 catcttggca ctacgtcctg tccccaccat aagggctgtc ggtgttgcaa gtcccaaggc
     3661 acaaggacag gcgataatca aaaccgccac tccgtagaga agagaggaca caaagctagc
     3721 tccaagcacg accacactat ccctgagcaa gacgaaccaa acccaaaagg tcatgattcc
     3781 taaaatgaca actactggga caaaaatccc tgaaatctta tccgtcaagt cctgaatcgg
     3841 cgcacgactt gtctgagctt tcttcacaaa atccacaatc tgagccaaaa cagtctctga
     3901 gccaactttt tctgctctaa agacaagcgt tccactatga ttgatggttg agccaatgac
     3961 agtatctcca actgtcttgt ccacaggcag actctcacct gtcaccatgg attcgtcaat
     4021 actagagaca ccttctacta cgacaccatc aacagcaatc ttttcaccgg gacgcactcg
     4081 aatcaggtcg cctaccttga cttgttccaa aggaacttgg acataactat catcactcaa
     4141 gacttctgcg gttttagctt gcaagtccag taatttctcc acagcttggg acgtattttt
     4201 tctcattttt tcctcaaaaa ctgctcccaa aagaacgaaa aagaggataa atccagcact
     4261 ttcgaagtaa acagggagac cagcaaagag agcaactagg ctatagaaat aagccactag
     4321 agttcccagc gcaaccaagg tatccatgtt ggcattgtgc tttttaaaac tggcccaagc
     4381 actctggata tatggcttac ctgcaactaa cataataggc gttgttgcta gaaaggttcc
     4441 ccaatgcatg acttgatgac taatgctacc tgtcaacatc ccaatcatga gaatcacaag
     4501 aggcacagta aagatactag taatccaaaa acgttgcagg agagatagag attttcgagt
     4561 cttctcaacg actatatagc ttcccttttg catcttcatg ccacaagaaa attcatgtcg
     4621 ccctaattct tgaggtgtaa aacgaatgac tttctcctca tctacgccga ttggttccaa
     4681 gataccttct tcttcaaaca gaatttcctt ataacagttt gaaggagtag cacgatgaaa
     4741 ggtaatctca gctggaattc ccttttgaag ctggatatgg gctggatgat agcctttttc
     4801 agctcggata cggatttttt gaatgccatt ttctaagctt gctttcacaa tttctgtcat
     4861 agtctccacc tactctacaa tcatcttgcc gtgcatcatg ttcataccac aagcaaagcc
     4921 aaactctcca acctgctcag gcgtgatttc cactacatac tcttccccca ttggcaggtt
     4981 cgcatgtaca ccaaaatctg gaaaaacaat ttgatccaga catggtgaag gatccttgcg
     5041 gtcaaagaca atgcgtgctg gcactgattt cttgaggaca atcaactcag gagtatagcc
     5101 tcccatgact tccactcgaa tctcttggta tccgtttttt tgctgggctt tttgtccaga
     5161 tttttcaggc tttttgaaaa accaaaacaa gataaacgcg ataagggcaa tacaaataat
     5221 ggttacaata ctatttaaca tgacgtctcc tttacataca attacatctt acttctgtta
     5281 cagcacttga tttcttctct gaaatcacag cttccaagtc ttccaagtca gtctgagtaa
     5341 attcacattc tacaatcaag tcagccaaca aattcctaat cctacgggaa caaaccttgt
     5401 ctttgatatc ttggacaagt aaatcccgac tttggtctag agttaaaagg gctgaataaa
     5461 caaaggactt gccttctttt ttccgagtca gacactcttt ctcaaccaaa cgagccaaaa
     5521 gagtttgaat ggtcgacttg gaccagtcga accgctctgc caaaacccta atcaaatctg
     5581 tactggtctg ctccccctgc atccaaataa tcttcatgac ctgccattct gcatctgaaa
     5641 tctgcattac catacctcca aaatctacat ttgtcaatta cactcatcag tatactctta
     5701 aaatctacat ttgtcaatta tagaaataat attttcttcg aaaaatagaa ttttaatcat
     5761 ttgaaaaacg atttgcagtc aaatattact atataaacaa taaaaatatg ctatactaaa
     5821 gaaaaaagaa aacaaccact aggggtgcgt aaagctgaga ttaacgactg ttagatccct
     5881 ctgactcaat ctaggtaatg ctagctgatg gaagtggaaa tgataatggg gactagcagt
     5941 cttctattgc ctttctaaaa cagactagct tgttcttaag aatacaaact tcagttggtt
     6001 gggaggtttt agatgactta tttacccgtt gctttgacca ttgcagggac tgaccctagt
     6061 ggtggtgctg gcattatggc agatttaaag tcattccaag cgagagatgt ctatggaatg
     6121 gctgttgtaa ccagtcttgt cgctcaaaat accagaggtg ttcagctaat cgagcacgtt
     6181 tctcctcaaa tgttgaaagc ccaattggag agtgtctttt ctgatattcc acctcaggct
     6241 gtaaaaactg gaatgttggc tactactgaa atcatggaaa tcatccaacc ctatcttaaa
     6301 aaactggatt gtccctatgt ccttgatcct gttatggttg ctacaagtgg agatgccttg
     6361 attgactcaa gtgctagaga ctatctcaaa acaaacttac tacctctagc aactattatt
     6421 acgccaaatc ttcctgaagc agaagagatt gttggttttt caatccatga ccccgaaggc
     6481 atgcagcgtg ctggtcgcct gattttaaaa gaatttggtc ctcagtctgt ggttatcaaa
     6541 ggcggacatc tcaaaggtgg tgctaaagat ttcctcttta ccaagaatga acaatttgtc
     6601 tgggaaagcc cacgaattca aacctgtcac acccatggta ctggatgtac ctttgctgca
     6661 gtgattactg ctgaactagc caagggcaag agtctttacc aggcagttga taaggccaag
     6721 gcctttatca caaaagctat tcaagatgcc cctcaactcg gtcatggttc tggtccagtc
     6781 aaccatacaa cttttaaaga ttaagaaaaa aactctctag ttcccacttt aagggaatta
     6841 gagagttttt atactcttcg aaaatctctt caaattacgt cagcttccat ctgcaacctc
     6901 aaaacactgt tttgagctga cttcgtcagt cttatctaaa acctcaaggc agtactttga
     6961 gcaacctgcg actagctttc tagtttactc tttgattttc attgagtatt aattaggaaa
     7021 gaatgtcatg caactttgtt aaaaaggctt gcgtttttgc ctcaatatct tctgcttgca
     7081 tcaaatcacg tacaacagct acaccagcta tgccagtgcc cataagctga tcaatattct
     7141 ccgaagtcaa gcctccaata gcaactactg gaatggcaac cgtttggcaa attgttttca
     7201 aggtcgatat cagagtaatg ggcgcatttt ccttggtggt ggttgggaaa atggctcctg
     7261 tacccaagta atctgcacct gatttctccg cttccagagc tcttttaacc gttttagcgg
     7321 tgacaccgag gattttttca ggacccaaga ctttgcgagc taccgaaact ggtaattcat
     7381 catctccgat atgcagacct gctgcatcaa ccgcaagaca aacatccaac cgatcatcga
     7441 ttatcaaggg gacctgatag gcatctgtta tttccttgac ttgttttgcc agttgataat
     7501 attgattggt tgtgagattt ttttctcgca attggactat ggtaacccct gaacggcagg
     7561 ccgtctcaac ttttgcaaga aagctttcca cggaatcttg atagcgattg gttaccagat
     7621 atagtctaag tgcttctcta ttcataaacc tctcctttga tggtatctag ccaattttca
     7681 tctcttctta ggagcgaaag ctgattgagt acttggtaac gaaattcttc caatcccatt
     7741 ccttgaacaa ctattttctc agcagcgata ttgagataag agactgctaa gcaagaagct
     7801 tcaaaaccag tctttccttg gctgagaaaa acggctgtta aggctccaac caagtctcct
     7861 gtccctgtta tccagtctaa ttcagtacag ccattctcca gtacagcaac ttgattctcc
     7921 gaaacaataa ggtccttggg gccagtaact aagaaagaca taccaggata ggtctgacac
     7981 cagtctttca agacttgaag caaatcctcc gtttcttgat ctttagcact cgcatcgacc
     8041 ccaacgccgt ggtgctttaa tccaacaaga cttcgaattt ctgacatgtt tcctttaagg
     8101 accgtaggtc tatagtctaa aaggtcttta actaagctct tacgaatgga tgaagtcgtt
     8161 acgccaaccg catctactac catcgggaga gaagattggt ttgcatacga agctgccatg
     8221 cggattgctt tttccttctc agctgacaaa tgccccaaat tgatgaagag agcctgactt
     8281 tgcttagtaa aatcaagaac ttcacgggga tcatctgcca tgacaggttt gcatcccaga
     8341 gccaaaatcc catttgccag catctcacaa gaaatctcat tggtcataca gtgaatgagg
     8401 gaactagagc ctataggaaa aggatttgtc aatgcctgca tcagtctatc ctttcagcaa
     8461 agaaatatcc ttgcactttt ttaaagaatt cctgcttgat taaaaatcta aatgcaataa
     8521 aggaaatcgc tgtaccaatc aaggttgctc cgaaaaatcg aggagtgtag ataaaccaac
     8581 taagcttagc agccgatcct gtaaagagca ccataacagg ataggaaaca atagaaccaa
     8641 taatacctgt tcccacaatt tctcccaagg cagaaaagta aaattttcga ccgtacttat
     8701 aaaagagacc tgctagaagg gctccaaaag tcgctcctgt gagagctaaa ggcggaatcc
     8761 cttgagtcgt catacggata aaggctgtca ctgtagccat agccaaggca taaacaggtc
     8821 ccatcatgat tcccgctaga atattgacta cactggacat cggtgccatt ccctcaatcc
     8881 gaaagatagg tgtaaggact acatcaaggg caatcatcat agataaaatg gtcaatttgt
     8941 gaacttgtag ttggtgcttt ctcatgtttc tattcttctc ctttttctaa agactgtaaa
     9001 tcgctcttcc atgtctggtg ttggtaagcc atctcccaaa acttggcttc catatgaaca
     9061 ctgatgtgga aggcatctag cattttttgc ttatctgtct catcactttc tcgataaagc
     9121 tgattgacca gtgctccctc ctctctgatc tgttgctcta actcatccgt aatataagtt
     9181 tcaatccatt gttgatagag aggatttggt gatggtttaa gattaagtga tttgcctata
     9241 tcatggtata accaaggaca aggaagcaag cttgcaaaag ctatggctaa gttcggttct
     9301 gcaaattgcc tataaatatg agaaatgtaa tgataacagg ttggagcgat tggatgttgc
     9361 tccatttcct ggtcgttgat ttccaattcc ttgaaaaatt gttggcgaat aaataactca
     9421 ccctccacta aaccctgagc attttgtttc aagagtcttt tcatctcttg gtttgaagtc
     9481 ttatcagcca aaagatgata gatttctgag aaagccttca gatagtaggc atcctgaatc
     9541 aggtaatagc ggaaaatggc aggttctaaa ttcccctctt gtaattgtaa aataaaggga
     9601 tgatgaaagg aagcctgcca agctttcttg gataattcca tcgcaatatc tgtaaattcc
     9661 ataataactc ctttataaaa atagactggt ttgaagcaat aaaaagaaaa gcaggtagat
     9721 taattttgtt tttttaggaa tataaaaagt ccgatagcta ttcttcaact gtgcatgttc
     9781 gtcatatccg taagcagata gagctctcag gtaaagatgg cgccacctaa agactgtcat
     9841 cagaacctta ctgtaaatca agggcgacca aaaatgtagt ttttgaccac gtaataggca
     9901 agcttctttg agggacttga tttcttgctg aatgagagga aaagaattga ataccacaat
     9961 caaggcatag gaccaagagc gtgatagccc cttttgagcc aagtacaaga gaagctcttt
    10021 tagtgaaata gaggaaacaa agacaaggcc gatacaaact gtcacaaagg ccctcgttcc
    10081 aagcatgact gcctgtgaag catctccgtg taactgaact gcccagtagt tggcaaaaga
    10141 tgggaaaatg gcaagtatga tcatccaagc taacatttta aatcgacggt aatagagcat
    10201 aaagagaata caaaatgcga ctaccgaaag attcagagca atcgaaggaa tgaaagatgt
    10261 ttccaaggat aaaatcagca agaagagact gataatcggt gtctgggttg ctactttgac
    10321 catactatct cacctcccct tgggtattgc tactctgaga tgtaagtggt ttggtaatgg
    10381 tcacttcttt cacatgccga agaccctgac tagtcatctc aatccaataa tcaaccacag
    10441 aaatcaaagg gtctaaacga tgactaatga gcagaaaact tcttccttga ttcctctcct
    10501 ccacaatcca cttgcaaaaa taatggcagg ctctatcatc caaacctgca aaaggttcat
    10561 ctagcaagat cacggaagcc ttactggtca agatggtcag gagctgaaga attttttgct
    10621 gaccaccact taattgatag ggactcttat cgactgcctg ctccaaatca aaatatcgta
    10681 aagcttgaaa aatccgctga tttctttcag aatcaggtcc atctaattga agctcctctc
    10741 gcagactgac tcggataaac tgcttctcag cttcctgaac aacaccagtc agatcacgat
    10801 acaaactctt tttctttttc aggaccgaac ccttccaagt aatgctcccc ttatactttt
    10861 gaaattgaag aatagaccga aagagggttg atttcccgac accattgtca cccaggatac
    10921 aggaaatccc ttgatagaat gtgaaatcag caattgaaaa gagggggcga ttaccaagct
    10981 caccagtcac acggttcata tggaatagtt ccgggctaga agcaacttcc tttgaagcaa
    11041 cctgtgtcat ctcataggaa gggatttgaa acacttccct tagttttccg tctcttagct
    11101 ccaccatatg gtcgatatag gctttatagt cagataaatc atggtcgcac aaaataactg
    11161 tcttcccatc atagaccaac tcttttagaa tctccaatat ctcgattctg ctcttgcggt
    11221 caatggaagc gaagggctca tccaagagat agaccctagg attcatggca aagaggacag
    11281 ccagcgctgc tttttgcttt tccccacctg ataagtgatg gatgagacgg tgcaagatgt
    11341 ccttgcaacg acattgctgg acaacctctg ctattttaga atcaatttcc tgaaggtgat
    11401 agccgatatt ttccatggta aaaaccaact cctcaaacaa gctctccatg gtaaattgat
    11461 gattaggatt ttgcaagaga ataccaaccg tctggacacg ttcgacgata gaaagctgac
    11521 tgacctcgct cccatctatc aggacttgac cgctataggg aagagaacta acttgggcaa
    11581 tcatttgaaa gaggctggat tttccagacc cactactccc aactaacaag gtaaaggctt
    11641 gcgcatgaaa agtaaaatca aacggctcag agaagattgg ggactgaatc gctcgtagtt
    11701 ccagacccat ctatgctttt cctccagttg caaactgatg atagagtttg acaatggcac
    11761 gaaccaagat ggtacagaag aaataaacag aaataaaacg taccacaagc aaggaaagga
    11821 caaacggaag ggaaaaggcg tagtaaccta acttaatgta ttcatagaca aagctaacaa
    11881 gcgtaatccc aatactatta gcagttagag agagccaact ttcatagcga ttcttagtta
    11941 cgataaaacc aaattcactt cccaaacctt gaacaaagcc agacaaaaga gctcctagac
    12001 caaattggct accataaagg acttcagcaa gcgcagctag cacttctcca atcgttgcac
    12061 ttccgactct cggaacaaag atggcagcaa tgggcgcagc catacaccag agaccgaaga
    12121 ggatttcatt ggcaaaggcc tgcaaaccaa gaggtgttaa gagtagactg agaatattat
    12181 acacatatcc tgaaccaacg aaaaccccac caaaaaagat agacaagaaa gcaagcaaga
    12241 taacatcttt taactgccat tttttcaaca taaaaaactc ctttttttaa agaaaagtgg
    12301 ggcactcaag aagaccgacc taaatacttt gtatagcaga ctgaatttag aacagtacac
    12361 aagaacacta aaatatttct agaaattaat ttgaattttc taattgattt gttcgcatct
    12421 tatttcaatc tactatatca tcttcatcca gtttcgtaaa agaaaaaact ctaattacag
    12481 atacaaatta gagttcagct tacaagatta gacagttctt ttcgacatac gaaaaaaaca
    12541 tttcacattt cccttcgcca gtcttaactg tatcaggttc aatgggtatc atctcagcct
    12601 aaagcacccc aaatgtcttt attatttaat tatgtgatta ttataacaca cattttatac
    12661 tagttcaaga aattgaactg gaaatacagc cttgcactca caaagacagc agatctttct
    12721 tttgcaaaaa acaaatgacc tgtttgatga attagccatt caagctgaat ctggacatag
    12781 ctttttaaaa aaggaaaatc ctacttactt agaatccaag gatagatatc tattgttcac
    12841 tcatttcccg aacagttttt tctatatttt ttgcatacga tattgccgaa atgattgaaa
    12901 cgccatccat attggtcttt ataatgtctt taatatgttt cgtctgtatc ccaccaattg
    12961 caactaaagg catttgtggc aatagttttc tcatcaattc aagaccttca taacctatag
    13021 taccaccagc atcatccttt gactgggtac caaatacagg cccaacacct acataatcta
    13081 catattcaac ttttgattgt tgaaattctt cttcgtttct tatagaaaga ccaattattt
    13141 tatctggcat caattttcta atttcatcaa caccaatatc atcttgacct acatgtacgc
    13201 catcggcgtc aatttccatt gctaaatcta tatcgtcatt aacgataaat ggaacattgt
    13261 attttttaca aagttcttta atttggatag ctagctcaag tttttctaag ccttctaaag
    13321 caccctcacc tttttctcga aattgaaata aggttatacc accttttaag gcttcctcaa
    13381 cgactgtata tagatttttt ccttggcaag tagtcgttcc acaaataaaa tatagtttta
    13441 gtaattcttt atgaaacatc ttacttcact cttttgaatt cctttacatc ttcatctgta
    13501 atctcgtata aggcatttat aaattcaact ttaaatgtcc caggaagatg tccatttgga
    13561 cgtttttctg ccatttctcc agcgatattg taaaccaaca ttgctgtttc taatgatttc
    13621 aattcttgac ctttttctag tccgataaag cttgctacta cagctcctaa taagcatcct
    13681 gtcccaatga ctttcggcat catagcacta ccattatgaa tcattaccac ttctccatta
    13741 acagcaatgg catccacttc acctgttact actattggaa tattgaactt ctcatttgct
    13801 gctagagcaa tttcgtcaat attatctacg cccgcactat ctactccttt agatgccaca
    13861 tctattccta ctaaagaggc aatctcgcca gcatttcctc taatcgctgc tagtttataa
    13921 ttgttgatta gatcatctgc tacttttttt ctatattctc ctgctccaca ggctacagga
    13981 tctaaaactg ctgggacatt atatttctct gcaattttca gagcagcttg gtataatttc
    14041 caattttcat ctgtcaatgt tcctatgttt attaataaac caccagcata ctttaacaaa
    14101 tcctctaaat ctgctggaaa ctcactcatg gctggtgagg cgcccagtgc tactaatcca
    14161 tttgctgtga aattttttac tacatcattg gttatacaaa tgaccaatgg tgctttttct
    14221 tttaataatt ttaaacttgt catattgaaa tccttccttt tcactttata cgatctactg
    14281 atttcgattt atttctatct ttcgttaaga atttttttca tttacattga atgatttata
    14341 ctcaatgaaa atcaaagagc aaactaggag gctaaccgca ggttgctcaa aacactgttt
    14401 tgaggttgtg gatagaactg acgtggtttg aagagatttt cgaagagtct tacctcatca
    14461 aatttgtaaa tatcatgagc cttctctaga catcgtaacc aatatcaaaa aaagctaatt
    14521 ctaaagcgac tgcttgattc cagcgttgct gaagttctgt caaatcttct cgatttttat
    14581 cgacacgatt gagttcgtca accagaaatt gaacccactc tgcaaagaaa ggacctctgt
    14641 ggagattgat ccattccgaa tgaatataga cttcaggtaa agccaaatct ttagaacccc
    14701 agtctaaata gagaccttct gcaatgacca gcatgaccaa aagatgggca tagtctgatg
    14761 aagccaccgc cgaatacatt agatcctgaa aggcttttgt tacagggtgc aaagtcactt
    14821 ctagatagtc attctctgct acttttaact ctttaaaagc cttttggaaa taaccatctt
    14881 catctgcttc aagaaagcct agttgcttgg caaaacgaag cttggattca agtttatctg
    14941 cgtgagctac gcaggcaccc agcatggata agaaggcatc aaagaagtga taatcttgaa
    15001 tcagatagtc ctttaagacc ttattctcaa ttgtccccgc aaaaagttcc ttaacaaaac
    15061 gatgattgat tgcagcctgc caatccttct gactgctttt taataattct ccaacagtca
    15121 aacctggctg aaatgcatag tcttgtgttt ccatatttac ttctcctctc tttacttgtt
    15181 agtaattaat aaaacaccaa gaaatatcaa gcaaaatcgt aattccactt gatcctttta
    15241 aagcacatcg agagcatttg cagagagcta actaaacaag cctatccagt ttatataaac
    15301 aaaaaactcc aattacaatc aagaattaga gttgacttac aagattagat cgttcatttc
    15361 gccatacgaa aaaacgtttc acatttccct tcgccagtct taactgtatc aggttcaatg
    15421 ggtattatct cagcctaaag caccccaaat gtctctatta tttaattact gaaccagtat
    15481 agcaaaaaat gaaagcccta gcaagatatt tgaccgaaaa atatctttat atataatata
    15541 ttgaaactag aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactgtc
    15601 ctgattgatt tgtcctattc ttatttcatt ttactatagt tttcgatagc aatttattct
    15661 tccaatacac gaagaaaaac ctccacattc agtggaggca atctgtttta tcaatacaat
    15721 tttaagtcac gagggtcaac tgggaaggtt gggttgtatg gattgtgacg gagcttaaag
    15781 tgtttgacat cttcaatggt ctgagctcca gacaattgca taactgtctt caattccgca
    15841 ttcaagtgtt caaagacttg acgcacaccg acactaccac cgagagccaa gccataaata
    15901 acagggcgac caatagctac caagtctgct cctgaagcca aggctttaaa gacgtgttga
    15961 ccacgacgaa caccagagtc aaagacaatc ggcacacgtc tatcaactgc ttctgccact
    16021 tcttgaagcg agtcaaaggc agctggtcca ccgtcgattt gacgaccacc gtggttggtt
    16081 acccagatac cagaagctcc tgcagcaagt gaacgttcaa cgtcctcacg gcattgtggt
    16141 cccttgacat acacaggaag accagagtat tcagcgataa attctacatc gcgtggagac
    16201 aagcgttgtt tagctgattt gtaaacaaag tccattgatt taccagcacc ttctggcagg
    16261 tattcttcaa caatcggcat gccaactggg aagacaaaac cattacgctt atccacttca
    16321 cgattccccc ctacagtagc atctgccgtc aagacaatcg ctttataacc ttcagccttc
    16381 acacggtcca tgatgtggcg gttgataccg tcatccttac taaagtaaaa ttggaaccaa
    16441 tggggtgtcc cttgaagggc ttcagaaatc tctggaaggt caacagtaga gtaagagctg
    16501 gttgtataaa gagaaccaaa ctcatgcaca ccacgcgcag tcgccacttc cccctgttca
    16561 tttgccaatt tatgagccgc aacaggcgcc ataatgattg gtgaagatag tttttcacct
    16621 gcaaattcaa tctctgtact tggattttca acatcgcaaa gtgtatgagg aacgatgagt
    16681 ttgtggttaa aggcgcggat attctctctt aaagtgaaag tatcttccgc cccactagcg
    16741 atatagccaa atgctgcttt aggaataact tgttgcgcca ttggctccaa atcataggta
    16801 ttgatgaagt ctacatgacc ttctgcattg cttgttttgt atgacataaa atgccctcct
    16861 tgattaagta agcgtttgct ttttactaca caactataat aactcttttt tcaatcattt
    16921 tcaagagttt tgcttaaaaa ccatcttatt ttttcataca atatactagc cctactttcc
    16981 ttaaactcta aactttagtc tatattaagt gaatcgttga gattttttgc tgccaggcat
    17041 ttgaactact tttttatttg cggattctat ctactaatac tataaaaaaa caagtgaata
    17101 agacaccaga acatcctcta ataggaccta tggacttata tcagtcccat atatactgtt
    17161 taagcaagat actatcctag ttgacgctaa cttcctatcc cacttattaa ttttttattt
    17221 atagtgaatc tgaacaaatc aattggggaa tccaagtcaa tttctagtac tttttgaaca
    17281 gtttcagcgt actatcgtaa aatgaaataa aacatgcaca aattgcttag ggaatttaaa
    17341 ccaatttcta acaatgtctt agaaatcaaa gtgtactatt tcaacttcaa tatactacac
    17401 ttcattttct ccttaaattc agtctctttt tgaatcaaaa aatcccctgg taagagccag
    17461 aggataagaa tttatttcat tgttgggaag agcaatacat cacggatagt tgttgtatca
    17521 gtgaggagca tgcagagacg gtcgataccg attcccaaac cacctgttgg tggcataccg
    17581 tattcaagag cttcaatgta gtcatagtcg atgcctgtcg cttcatcatc accaagttct
    17641 ttggctttag cttgggcttc aaaacggcta agttggtcga ttgggtcgtt caactcagta
    17701 aaggcattac cgtactcctt agtcatgata aagagctcga aacggtcagt aaagcgttgg
    17761 tcttcaggat ttttcttagc gagtggagat acagctactg gatgtccata gacaaaggtt
    17821 ggttggatta aagtttcttc aacaaactct tcaaagaagg cattgatgat gtgaccaacc
    17881 tcagtgtagt gtttctcaac tggaactttc ttctcagcag cgatagtttt agcttcttcc
    17941 aaagtcatgt cttgccagaa atcgacacca gtaatttctc tgatagcatc caccatatga
    18001 acacgcttaa atggttcgtt aatcttgatt tcagtacctt ggtagttgac tgggccatca
    18061 cctttgactg atttagcagc gtgttggata atgccttcag tcaagtccat gatgtcttgg
    18121 aagtctgcat aagcttggta aacttcgata gaagtgaact cagggttatg agtagcgtcc
    18181 attccttcgt tacggaagat acggccaatt tcatagacac gttccatacc acccacgata
    18241 aggcgtttca agtgaagctc agtcgcgata cgaagcacca tgtcaatgtt ttgggcattg
    18301 tggtgggtga taaatggacg ggcagcagca ccaccggctt cattatgaag aacaggtgtt
    18361 tccacttcaa ggaatccttt ttggtcaagg taacgacgga tttcagagat gatttttgaa
    18421 cgagtgacaa agcgttcaaa gctttcacga ttagaaatca agtcaaggta acgtttacgg
    18481 taaattgttt caacgtctgt caaaccatgg aatttctcag gaagaggacg aagagcctta
    18541 gacaagtgtg tgatgtgggt tgccttgata gagagttctc ccatatccgt acgcatcact
    18601 tcaccttcga caccaaggaa gtcaccaagg tctgcttttt tgaagatttc gtagttttct
    18661 tcaccgacag catccttacg aacgtagatc tgaatctggc cttcgcggtc ttgaaggtgg
    18721 gcaaaaccaa cttttccttt accacgtttg gttatcaagc gtcctgcgat agtagctgtt
    18781 tcgtttttat cgtgtaattg ttctttatcg aggttggcat atttatcttt taattcttgt
    18841 gaatttgcag tacgttcaaa acgttttccg aaaggatcga ttccttgttc gcggagcgca
    18901 gccatttttt cacggcgaac gatctgctgg tcatttagtt cttccatatg ttctgtagac
    18961 atgggatcct cctagtttta ctcaaaattg aatacgatga gtcatttttt gcgatactcc
    19021 cattttatca taaataagca agaaattcac ggataatctt taaaaactaa aaagaacctg
    19081 acgctaaaat cactggaaag aagtgaaagt atctcccgcc ccactagcga tatagccaaa
    19141 tgctgcttta ggaataactt gttgcgccat tggctccaaa tcataggtat tgatgaaatc
    19201 tacatgacct tctgcattgc ttgttttgta tgacataaaa tgtcctcctt aataagtaag
    19261 cgtttacttt gtgtattaca aaaatatctt aactcttttt caaaactttt aaaatatttt
    19321 gtttggaaat ttcagaaatt ttatgtctat gataaaaatc cttataacgg caataaaaaa
    19381 tagatattat ccaaagaaga ttttaagtgc tacaataact gtattatttc tagatgggag
    19441 gttctatttt tggattgatc cattgttgaa caatatctac cactatatca aaaggcattc
    19501 tttctgacct tgcatattgc agtttgggga attttgggat cctttctgct cggtttaatc
    19561 gttagtatca tccgacatta tcgaatcctt gttttggcgc aagtagcgac agcctacatt
    19621 gaattgtcac gtaatacgcc ccttttgatt caactcttct ttctctactt cggtcttccc
    19681 cgaatcggga ttgtcctatc ttcagaagtc tgtgcaacgc ttgggcttgt ctttttagga
    19741 ggctcctata tggcagaatc tttccgaagt gggctggaag ccatcagtca aacccagcag
    19801 gagattggcc tcgctattgg tctgacacct ctacaggtct tttactatgt ggttcttccg
    19861 caagcaacag cggtggcact cccctccttt agtgccaatg tcattttcct tatcaaggaa
    19921 acctctgttt tctcagcagt ggctttggcc gacctcatgt acgtcgccaa ggatttgatt
    19981 ggtctctact atgagacaga cattgcgcta gctatgttgg tagttgctta tctgatcatg
    20041 ctgctaccca tctcactggt ctttagctgg atagaaagga ggctccgcca tgcaggattc
    20101 gggaatccaa gtactctttc aaggaaataa tctcctgaga atcttacagg gattgggcgt
    20161 tacgattgag atatccatcc tgtctgtcct cttatccatg atgttcggaa cagtcatggg
    20221 aatcatcatg acctcccatt ctagaatcat acgattttta acacgattgt atctggactt
    20281 tacccgtatc atgccccagc tggtgctact cttcatcgtt tactttggct tagctcgaaa
    20341 ctttaatatc aatatctcag gtgagacttc agctattatc gtttttaccc tctggggagc
    20401 agctgaaatg ggagacttgg tacgtggagc tatcacttct ctccctaaac atcagtttga
    20461 aagtggacag gcactcggct tgactaatgt tcaactttac taccacatca tcatcccaca
    20521 agtcttaaga agactgctac cgcaggctat caatcttgtc actcggatga ttaaaaccac
    20581 ttcattagtt gttttgattg gggttgtgga agtgaccaaa gttggacaac aaatcatcga
    20641 tagcaatcgc ctgaccatcc caactgcttc attttggatt tatggaacca ttctagtctt
    20701 atatttcgca gtttgctacc ctatttccaa actatccact cacttagaaa aacattggag
    20761 aaactaaatg tctgaaacta tcttagaaat caaggaacta aaaaaatcct tcggagacaa
    20821 tcccatcctc caaggacttt ctctagaaat caaaaaaggg aagttgttgt catcctaggg
    20881 ccatctggtt gtgggaaaag taccctcctt cgttgcctca acggcttaga aagtattcaa
    20941 ggtggagata ttcttctgga tggtcagtct atcgttgaaa ataaaaaaga ttttcaccta
    21001 gttcgccaaa agattggcat ggtctttcaa agttatgaac tctttcccca tctggatgtc
    21061 ttacaaaacc tcatcctagg ccctatcaaa gctcaaggaa gggacaagaa agaagtaacg
    21121 gaagaagctt tgcaattact agagcgtgtc ggtttgctgg ataaacaaca tagctttgcc
    21181 cgtcaattat ctggtggaca gaagcaacgt gttgcaattg tccgtgccct cctaatgcat
    21241 ccagaaatca tcctttttga cgaggtgact gcttcgctgg atccagaaat ggtgcgtgag
    21301 gtgctggaac ttatcaatga tttggcccaa gaaggccgta ccatgatttt agtaacccac
    21361 gaaatgcagt ttgcccaagc cattgctgac cggattatct tcctcgacca agggaaaatc
    21421 gctgaagaag gaacagctca agccttcttt accaatccgc aaaccaaacg agcccaggaa
    21481 tttttaaacg tctttgactt tagccaattc ggctcatatc tataaaggag attcttatga
    21541 aactattcaa accactctta actgttttag cacttgcctt tgcccttatc tttatcactg
    21601 cttgtagctc aggtggaaac gctggttcat cctctggaaa aacaactgcc aaagctcgca
    21661 ctatcgatga aatcaaaaaa aaagcggtga actgcgaatc gccgtgtttg gagataaaaa
    21721 accgtttggc tacgttgaca atgatggttc ttaccaaggc tacgatattg aactagggaa
    21781 ccaactagct caagaccttg gtgtcaaggt taaatacatt tcagtcgatg ctgccaaccg
    21841 tgcggaatac ttgatttcaa acaaggtaga tattactctt gctaacttta cagtaactga
    21901 cgaacgtaag aaacaagttg attttgccct tccatatatg aaagtttctc tgggtgtcgt
    21961 atcacctaag actggtctca ttacagacgt caaacaactt gaaggtaaaa ccttaattgt
    22021 cacaaaagga acgactgctg agacttattt tgaaaagaat catccagaaa tcaaactcca
    22081 aaaatacgac caatacagtg actcttacca agctcttctt gacggacgtg gagatgcctt
    22141 ttcaactgac aatacggaag ttctagcttg ggcgcttgaa aataaaggat ttgaagtagg
    22201 aattacttcc ctcggtgatc ccgataccat tgcggcagca gttcaaaaag gcaaccaaga
    22261 attgctagac ttcatcaata aagatattga aaaattagca aggaaaactt cttccacaag
    22321 gcctatgaaa aaacacttca cccaacctac ggtgacgctg ctaaagcaga tgacctggtt
    22381 gttgaaggtg gtcattaact cttaaaaggg actggatttt aagctccaat ccctttttaa
    22441 gattttacct ataacatcct gagtctatct aagatgttca atctgaacac agtgtacata
    22501 ctttatcttc tattgcatat actttatcac ataagatacg aatatcctct tcactatgac
    22561 tagcaatcaa aattgttgtc cctttttcac tagagagctt tctaaacaat gttctcatat
    22621 tttctacact tgatttatcc aaggcattca taggttcatc tagtaaaaga atagagggat
    22681 tctccatgat tgcttgagca atccctagct ttttcctcat acctagcgaa taagttttaa
    22741 ctttctggtc tttttgctca tatagaccaa ctattttcag tgtatcattg atttcctgat
    22801 taccaactac tcctcgtatg cttgccaaat attgtaaatt cttaaagcca ctataataat
    22861 ttataaaacc aggttcttca atcaaagctc ccaaattagc tggaattttt ctctcaggaa
    22921 caatattttc cccattgatt aacacttctc cataagacgg actatataaa ccagctatta
    22981 atttaaacaa tacacttttc cctgagccat tcgcaccagt aattcctata atttccccct
    23041 gtttacaact aaagttaagg ttttgaaaaa cacatgtctt ttttaatttc aactcaatat
    23101 tttttaatat aattatttca ttcattctat aaacctcctc ttttgacgag tgaaatagaa
    23161 aatgctttga aaaagaaaga ctaaaaatag caactgaaga aacaaatctc cccctacatc
    23221 cccattccct cgattcaaaa tataaaatag ataattagtt cgatttccta caaatagacc
    23281 accaaacaca atcatgagta aaaagaaact aacgcaagca aagttcattt gtacattcgc
    23341 tcctagtgcg tataacataa agcaaaacaa gactaacaca caagcattca aagaatcaac
    23401 tataaacaaa actcctatat cccagtttgg taactgtaac ataaattgaa tcactagaac
    23461 ttttaccatg attaaaatga gtccataaag aaaacaggtc caaatctgat acctaatcca
    23521 gagcttaata gaagaaaatc gaatcacttc cataaagaaa tcggatgctc ttctacgata
    23581 tacaactgct agaaaaaatg tatgaataat aaaccaatga agcaaccata tagataagac
    23641 taaaaaagag ttttgactca gattaggccc ttttaaaatt tctataacaa gtctatcatt
    23701 tccttctaac caataccata atcctaaaca aatcaatatc caaaaaagaa cataacccca
    23761 aaagtacttg gtatagatta tcttattcaa cctccacatg tgactactta actttcccat
    23821 ttccaacttt tacactctcc tccagtttct atgaacagaa aatacagtca atggaattat
    23881 gatagatagt aatgtaagcc aataaatcaa tgcatacgga ttggaattta ccatatactg
    23941 aaaaattggc aataatccaa ttatcccatt gttcaactga taaatccaga ataaggattc
    24001 tacaaataaa aaagtaaaca gaaatactaa gctcatgttt gattttttaa accaagaaaa
    24061 actgctaata gtaagtaagg ataaaaagaa atagtatgct atataagaga aaaaaaatcc
    24121 tataaagaaa ctagcattgt ttgcaatact tataccataa aattctctta aaaaatcaac
    24181 ctcctttatc tccaaagaga agctaaaacc attactaaat gcaattagaa aaatcaataa
    24241 aaataaagtc gccgtccaaa tccccgtact aagagctgct aatttgaaac taaaactggt
    24301 aaagtgctta attgatttca gacgaatgcg acactccaac ctattaaaat agttattcat
    24361 caaataaaaa aagaacaata tatatgtgaa cggaaagcaa tatactccag tcgtcatatc
    24421 ttgaagtaaa actaaaatcc attctaatac atttggatgg attgaatatt ggcgacagcg
    24481 caataaatat actgtactag ataaaacaca ggatagcagt aatataaaat aaaccaatac
    24541 tgataaaaaa tcttttttgt aaaattgaac aaattgtttc attatacata gtcctctgaa
    24601 tgtagaaaaa atgtaccata aacaaccaaa caactaacaa ataaaataaa agcaagatgc
    24661 ccactaacta aggaaagact gatatctttc tgatatccca aagctaatgt tgtcacaggt
    24721 tctaagtaag atagccctaa aatagcccaa aaaataccac caaccatcat ataggcaact
    24781 gggatgaaaa tagctcctat ttttttcttc actagcaaag cactagctag tccaaaaata
    24841 gagaacacag cgccccaaac tccataccag agagtcgtca caagactata gagcaactga
    24901 ttagaatcaa ataattcttt taaggcacca ctataatctc caatataaat ttcctgataa
    24961 ggagtcacta aaagattaat tcctaataat aataaatagg ggagaaaaaa gactagaaaa
    25021 gaagaaataa ttgcagtact acctacaata gccagatact tctttttaga aattcggcac
    25081 aattgtgctg ttagaaaatg actctcagca tcctctatta tctgactaga atagggcagt
    25141 gtacagataa gtgcagctac taggctaatc ggtgaaaatc ctcgaataga agaagcggca
    25201 aaaaaaatcg ataaaccttc aattttataa ataccattga aagcaaggaa atttcctaaa
    25261 ctcatgcaaa gaagggtcaa aaataaagac atataaaatc gaggtgattg aacgactcgt
    25321 acaagattac aaatgaaaaa ttccatcctt actcctcctt ataataaaaa tagggtgtag
    25381 cattcttttt tcatgctaca cccacaatca accatcttta aggcttactc tgacaagtaa
    25441 gttaataaga atctggactc caagaacctg aagtatgaat tcttacatga tttccaaatt
    25501 gtggcgccat agctaatcta gtaccagaac caatataatt gtcaccacct ccattatagt
    25561 acatgacaat cctagagcca gaccccaatg aatataccgg ggtaatatct gacccactat
    25621 aggcgctacg aatagaggta tttaaccttt taccgccacc agtgctgtca ctattattaa
    25681 ttccagcaga ggcgttttct ttctcaagct cactagttgt atccgaaccc caacgcggca
    25741 acgttaaatc ataatttcca atctgtctag ctaaaactgt agggagaaac aaactagatg
    25801 caattgtaac tacgcaaaaa aggaatatat ttttcttctt ttcatgacat cgtcctctta
    25861 agaagtgata aacaagatag ttgattgatc aatttgatac atattacatt ttcattatat
    25921 caataaaaga aagcgttgtc aattatttta tttaaaatat tgtcatattt taaataaaat
    25981 ggtaaaagag actcggtagc ctcgtctctc tttatcttac tgacctaacc ttcttgccaa
    26041 ttttcttggt cttctttaaa gcgttttaga agatcaaggc cctctggcgt gatgtaacct
    26101 tcttcttggg ctagatggat aagctctcta tagtttgaaa gcgtcacaag tttaacacca
    26161 gcatctgcaa agttcttatc tgcttttggc aattggtagc tgaaaatcgc tacaactcca
    26221 agtacatctg ctccttctcg cttggctgct gctacagctt caagaactga accacccgtt
    26281 gaaataaggt cttcaaccac taccattttt tgaccttgag ctacgcgacc ttcgatttga
    26341 ttaccagctc cgtggtcttt tggtttgcta cggatgtagg caaaaggcaa gtccatctta
    26401 tcagcaataa tggctccgtg tggaatccct gctgttgcag ttcctgcaat cacttctact
    26461 tcaggaaagg cttctttaat agcttccaca aaaccatttt caattagggt acgagtttct
    26521 ggataggcta gtgtcacacg attatcagtg taaatcggtg acttgatacc agatgcccaa
    26581 gtgaagggtt cctctggttt gaggtaaacg gcttggattt tcaagaggtg gctagcgata
    26641 tctttagcaa gtgtcatggt attctccttt tatttttcta atctagttct ttaattccag
    26701 ttctgtgtcc attcatcctt gatggcatga taagctgcaa caggatcctc agcttgggta
    26761 atgggacgtc ccactacgat atagtcactg ccgatttgat aggcatcagc aggtgtcatg
    26821 actcgttttt gatctccaac tgcaacacca gctggacgaa tccctggtgt cagacagata
    26881 aaatctggat tggtagcctg cttgatgact tgtacttcct gagccgagca aacaacacca
    26941 tccaagccag cttcagctgt cttcttggca tagtgaatca cagactcttg cagactggtt
    27001 tggatatttt gaaactcctg catctgagct tctgacgttg atgtgagctg agttacagcg
    27061 atcaatttgg cttgactccc aagaccttca cgcgccgcct tcatcatctc tacaccacca
    27121 gccgcatgga cattagtcat atcgacacca agctgagaca agaccttcat ggctgacttg
    27181 actgtattag gaatgtcatg aagtttgaga tccaaaaaga cactatgacc caaacctttt
    27241 aagtaggaca caatctcagg ccccgctgcg taataaagct ccatccctac cttgagataa
    27301 aggctttctt ctgctgggaa aagagctaaa aattccttga ccgcctcaaa actaggaaaa
    27361 tcaagagcaa tgattggacg atgttctcgc ataggtttct ccttttacct ttactagtga
    27421 gagagtctgg ccaacagaag ccacgaaaaa aggaacctgc caacagcaag gttccacgaa
    27481 aaatgggtag tctccaccct ttcaccgtct aaccttagct gcctctctgg actgctttaa
    27541 aggttttcta ttattctatt atttctacta gcacttgtca agtaaaaact tagtcacgta
    27601 tgtgttgact gctattgaac acctcacaag actctttcca aaagaatagt taaagacttt
    27661 cacttaggac agagaaaaag agtttgcttg ttacccttta attgaacaaa tgggaattct
    27721 gttttatttt gcggatgcct attcatcttg gcaaagggga agtaatgaga atgcgaatgg
    27781 acttcttcgt gagtattttc ttaaaccgat ttggcaacaa ttaccgaaaa aatccttaat
    27841 ggtgctttgc tagcttatta atcaccgtcc ccaaaaatac ttggattaca agacaggttt
    27901 tgaagcactt atagaggaaa tttaaaaatg ttgcattttt tattgcaatt tatcagttat
    27961 cttatcaccc aaaacttctg caattagtat gagcactatt gttatttttc ttttttcgta
    28021 cactcaaatc aaaatatagc aataagacta ttctgtagaa ttgctgtcaa aaagatcagt
    28081 tcatttttcc ttcccacttg tgtttataat cattaaaata actcaattaa gaaattttct
    28141 ttttcctaat agttatcgta attaaagtta atagaagaac aatccaaata agtagtgtta
    28201 gattaggaat tagagtttta ttccatgaaa atccctccca ttttgtgaaa aacttagtaa
    28261 acagtcccat aaaactataa tctgttatct tcgcaactgt cttatccaaa ccagatagca
    28321 tcggtaagaa agcaactaaa atcatagcag gaagactgat aacctgagct actacttggc
    28381 tcttcgcggt taaacctatc aataaataga ataaaatgat ggataaagag gttagaagaa
    28441 cgattgtaat ataattaaaa gtatgtacaa ttgtaactcc taaaataaga ggagtagttc
    28501 ccataatcac aaaagttagc aaaaaaggaa gaaacatcgt tgataaaatg tattcggatc
    28561 ctttaacacc actcaacaga agagtttgta aattgtactt ttctttttct tcagacaaga
    28621 taatagttat aggacttcca acagccaaag ccaaagaaaa aggtaaacac atcatcaaaa
    28681 gaactaatgc ctgttgatcg ttgaccttcc cctgtgtttc cataagatat ttataaaaat
    28741 atgtgaaagc aaaaggcact aaaacttgca ataaaatact cttattggaa aggataattt
    28801 gacaacgcaa ccataccaaa gccagaaacc gtttaagcat ttagctttcc tcctgttaat
    28861 gtgataaaaa tatcttctaa agtaggctca catgaatgaa ttgaaaaaat attttccaga
    28921 tcagcctgag atacctgttc tagtgatgta aaatcaaaag ttatctgatt cccattataa
    28981 tctgtaacct taatcttttt atctttatta tatctttgaa tgagttcaga aggagctcct
    29041 tgctcaacta atttcccttt atttaataag gcaacataat cacataaaag agttgcttca
    29101 ttcatatcat gagtcgttag aaaaatcgtt gtccctgctg ttttcaattc taaaattaac
    29161 tcatgaattg ttcgagaagt tgtgggatct agacctgagg tcggttcatc cagaaagagt
    29221 acagcgggtt tgttgataag agctcgtgct aaaagcattc gttgcctcat tccagtggat
    29281 aattttcctg ctaccatctt gcgactatca tataatccta ctcgctttaa caaattatca
    29341 acacgtgatt tactaatatt ataaaattta ctataaaaaa gaagattgtt atacagagac
    29401 attttctcat aaaatccact tgtatcgcta accaatccaa ttctctttaa ttcaccgctt
    29461 gttaaatttt gagatttttg tcccaaaata atagattgtc ctttatcggc aaggaactgc
    29521 ccagtcagaa tattaatcgt tgtggtcttt ccagaaccag atggtcctaa aaatctaacc
    29581 ttctttaaca gtgaagctta tattatttaa agctatttta tcaccaaaac tttttgataa
    29641 atggctaact tcaatcatac tcattgcacc tcctttatat tctacatttt tacttaacat
    29701 ctatttactt atctttatca aataaacgtc ttaaaaaaaa caataacatt aagcatataa
    29761 ccgttagcaa gattgtttca atattattga taatacgata cattctcaag cagtataaaa
    29821 taattatata tatgcaaatg ctcattatac ctattttttt aaacatacta agcctccttg
    29881 ctaaataata aagttatata ataactaaga cacactatac ctaacataat aaatatccac
    29941 tggtaactga ataaatgttc taaaattaac aagcaaaaat aaaatctcaa acgatgaaaa
    30001 aagccatact atattttcca atgatgtttg aatattttta ttgtagtaag cataatatat
    30061 agcaaaaata atacccaaga acaatactat taattgtgtt tctataacag tgaactgccc
    30121 aatagcagat aaaaaagcta ctcctcctga taataagcaa aaacaaactg aacgaataaa
    30181 tgttttcgct ctaatattgt tatctttcac tttattattt ttttacaaat tggacattct
    30241 ccgttttcca gaacatattt ttcttgactt agagcatgat ttctcatatt ataaacgtaa
    30301 gcgttatcta ttaggatttc attataacat cccagaaata ttttaattat taaattagtc
    30361 attatccctc ccaaaatagc aggcatctct ggtgtagtcg gccactttgt cttatcagat
    30421 aaagtgtact tatttatatc tttgtttata ttccgacaac caaagcaaga accgatggta
    30481 gggatatata ttatcagtaa taagatagca tccattaaac cctcctgata tgtaggatat
    30541 cttatgcgat acagcaaatt gattgacaat ttttataata tcaatgggcg tatcaattgc
    30601 tttaacgata aaatctatac tcccatattc cgcaacaatt ttttctaatt cttctactga
    30661 agaaacttta atagaaatag gtactacctg aacatctgaa ttatacttgt gtattttttc
    30721 agaaagaaca ttaatcttct ccttaccaac atccgactct gtataaagaa tttgcctatt
    30781 taaatttgat ggttctatta tatcgtaatc agcgacaata agtttcctca ctccatacat
    30841 acttagactt agagatatat aacatcctaa ggctcctgct cctaatacta atactgtttt
    30901 attctgtatt ttattatact cttcattata aaataacgaa tagtaacctt tagttctaga
    30961 atatctacta tcaatatcta tctcatccga aattaaaatt tgttcattta atagttcaaa
    31021 tgttagttta ctgcctaata cttcttctat ctctaatagt tccttacaac tattaaatag
    31081 atcgttgata aattcttgcg aaatttgagg ttctatagct atttcccgca tactccgacc
    31141 acgcaaatac attatacctt cttttttata agcaaaaaca taactattta cgtagaacat
    31201 atttcgtcct tcctctcata tataatatag aaagcagtat agaaacaacc acccctccta
    31261 tactacgaac aataatatta ggtgtcaaaa actgtaatag ttgactcaaa gggaaataaa
    31321 taataacaaa tgctattaaa agttgaacta tatattgaaa attcaagtta ttattgttag
    31381 aattcaagta tcttaaaata ataccactat catactgaaa aaaaggaatt gaattaataa
    31441 aaatcatacc taagttaatg ataaaaaata agagtccaag caatttatac gatgtgaaca
    31501 ataaaacaag taaacctgta agtgataaaa tcgaatttga agcaattcct gctaacataa
    31561 ttttcaaaaa ttgtttttta ttttttaaga attgcacccc acttaaatct acaaaaaaaa
    31621 gccaaattaa acaaaagtag cattattcca caatttggga tctcaatttg ataattatta
    31681 gcaattattg catgactaaa ttcatgtatc gttgcagaca taataacaac aagcaaccaa
    31741 aataaaagaa tgtttagcgt tattggaaag ttttggaaat tagtcaaaat atccgcccta
    31801 taaatataca taataaaaca ttgcaaaata agagccaatg ggaaaatacc aaataggatt
    31861 ttttcaaaat tcttattaaa tcttttatag tttaattttt cagataatgt tatattaaag
    31921 tcccaagata ttttaaaaat atttatcttt tttcgtgatt tcatagaatc tataagtccc
    31981 attttactaa gaacaatata aaatcttaaa taatatttct tccctactaa cactaataag
    32041 tccgatatgg taaattcttg acctattagt tgctctaacc atttttttcc tgtttcccaa
    32101 ctaatacatg tttcttacta gatggtatat atagatgata ctgtccctca taaggagtag
    32161 gtaatatctt aatcttatca acaattctca taacaaacct aacctttaat aaataaaaga
    32221 ggggctaagt aaaacatact ctagtccctc agtccgcaat caataaaata atgactaatt
    32281 ctattaatct cttgctgcaa gactaatacg gaaaattcaa atgactgtct aaaatgaaat
    32341 tgaaaaagct tgatgttagt aaatgaacaa acttcaacaa ccagcaagag caaggattgc
    32401 taaaccaaat ccgatacctg ttgcaagtcc agctgaaaaa tcactaactg gtactgaaat
    32461 ttcttcaatt tcctcaaata aaaagttatc ttgcatgatt atcactccct atctttttaa
    32521 caacaggcta ttccaattaa gagaactacc ccagttccaa gtaaaactcc cccaaaaatt
    32581 caccatctgt aggggctacg atttcttcaa tttcttcaaa taagaatgct tcatctgaca
    32641 tatgtgttac cttcttcata aaaaattatt ttgtaatcga ttacattgca aatgtaacat
    32701 aaagaaaaac agatgtcaaa tattaaacgt aagaacatgg tcactaaaga actataagag
    32761 aaaaggtaaa cctagcgacg cgatgagcgc tgggtcgttt gatttcgatt gctctcttcc
    32821 tcttgttttt tctgttcttc ttcctgtttt ttctcggctt ccttggcctc ttgtttggct
    32881 ttttcctcag cctccataat taatttatcc gccacagtgt aactgtaaat tccagcttcc
    32941 atgtcgacca cactcggttc tgacaattgt ggcttaatct tactgtaata tggcagtttc
    33001 ttactcattt cagatagagg aaccaagact tcgtccgaat cattcatggt caatcgaatt
    33061 aaatcggatg tcaccttgct tggggctaat tccacctttt ggatagccgc cttgagttct
    33121 gggctaattt gagcaagttc tgagacaaaa accttgattt gttcactatc attaaagaga
    33181 actgataaat aagtttctgg taaactgttc agactcacag aactagtctc aagctgacca
    33241 ctggaaagaa taggataatg attttcacca gaaatatagt aggccacaat atcatattcc
    33301 ttgaccttaa tagtgaactt agttggaaat tgatagacaa gttgagctga ttcaacccaa
    33361 tagttagact taatctgctt ttcatatttt gccttgtcta gcagaaggtt aatcgtataa
    33421 tccgaatcct gaatgcctga agcctgtcga atatcatcag ctgtagtttg caccgttccc
    33481 tcaacacgaa tatctttcat ggtcgcataa ggactgagca agtaggcaga gacaatcaat
    33541 aaaagcagac ttggaaataa aatcgtgaag gctcgcaaga tatggatacc aggaatcttt
    33601 gctttggctg gtttttcctt tgtagccttt ttagaaagct ttttatcctg ttcctccttc
    33661 tctttagact ctggttcttc tttctcttct ttctctttgt cagcctctga ggatgctact
    33721 ttttcttcag actcttcctt agctgattct gaatcttcct ggtctgtttc actctcctgg
    33781 tcctgtttgt cctctgactt ctcagattct tctcccattc gagcttgtct ttccttttcc
    33841 ttctcctcag ctagagccgc ctcttcttca gccttctttt ttagatattc ttggtttcgt
    33901 ttctgccatt ctgataactc tttcaattct tcgaggattt ctttgtcctc atttttctta
    33961 tcttttgaca tttactttcc ttatgataaa tcttttttca acaattgata aaaatctgct
    34021 agagatttca attccttaga agccttcatc ttagcttggt aatcttcctt gtgacttagt
    34081 aagtgagaaa gcttctcttc caaactatcc aaggtcaaat cgctttcttg aaggtcttct
    34141 gcatagcctt tttttacaaa gtaagctgca ttttcaagct ggtcaccacg actagcttca
    34201 cgaccaagcg gcacaatgac atgcaatttt gctatcgcca agagctcaaa aatcgtattg
    34261 gcaccacctc gtgtcacaac aatatcagcc aattccatca agggttgata gagatcggtc
    34321 acatagtcaa cacgaaaaag attttggctc aactcattca ggctagaatc tccagttaga
    34381 ttgataatat tgtagcgctc tgttagttct ttcttatggt ctgtcaccaa ttggttaaag
    34441 acacgagcac ctgcagaacc gccaacaaac aatacagtcg gcaatttatg attaaagtgg
    34501 ctttgaatat ccaccaattc atctggttct ggattttttt gatctgaaac cttggccact
    34561 gctcccacat gctcaacctt agacaaactc gaagcttgct caaaggttga atacatctta
    34621 gtcgcaaatt tataggcgat tttattggcc aagcccatag acaggtcaga ttcgtgaata
    34681 aagacaggca ctcctgacac acgcgcagcg ataacaggcg gtactgagac aaagcccccc
    34741 tttgaaaaaa gggtctgtgg acgaagtcgc aacatgataa agagcgattg gacgattccc
    34801 cagcaaactt tgaagacgtc cagcatattt tgccaagaga aatagcgacg caattttcca
    34861 gtcgcaatag aatggaaggt gacatccaaa cctgacttaa ggatttcttg gtgttcgata
    34921 ccacgcttgt ccccgatata gtggacttcc caaccatctt cgatgaactt gggcattaac
    34981 aaaagattga gggtaacgtg tccaaccgtc cccccacctg taaagacaat ttttttcata
    35041 ttattctttt aactccgcta ctgtgtcgat aaagaggtcg ccacgtactt caaagttagc
    35101 atacatatcc cagctggcat tggcaggact aagaagaacc acatctcctt gagtcgcaag
    35161 ctcataggcc ttgcgggtcg catctgcaat atctgtcgcc tccacataag cgacaccagc
    35221 cttgtctgct gcccgtttga cacgttctgc agattgaccc aggatgacca tcttcttgag
    35281 tccagtaatg tctggcacca attcgtcaaa ctcattgcca cggtccaaac cacctgcaat
    35341 caagacgacc ttgctgttat caaatcctga caaggctttt tgagtagcca agatattagt
    35401 tgatttactg tcgttataga atttaacacc cttgatgtca tccacaaact ggagacggtg
    35461 tttgacacca ccgaaggctg aaagagtttc cttgatggtt tgattgtcca caccacgaag
    35521 cttggctaca gcaatagtcg caagggcatt ttccacattg tggctacctg gaacaccgat
    35581 ttcattcgct gccatgacta cttcaccacg gaagtagagt tgaccatctt ccagataagc
    35641 tccatcaacc ttttcaagtg ttgaaaatgg tacaacagtg gcttctgtct tggaagtcaa
    35701 gtcttttgcc aagtcttgat taaagttcaa gacaaggaaa tcagctgctg tcatcttgtt
    35761 ctggatattc cacttggctg ctacatattc cgaaaatgac ccatggtagt cgatatgagt
    35821 tggcatgagg ttggtaataa ccgcaatctc tggatggaat tcttgaacac ccatgagttg
    35881 gaaagaagaa agttccataa caagcgtgtc cttatctgat gctatttgag caacctgact
    35941 agctggatag ccgatattcc ctgataaaag accatgttgc ccagcagcag tcaaaacttc
    36001 cccaatcata gtcgttgtgg ttgtcttacc gttcgatcct gtgataccaa taatcggtgc
    36061 ttctgaaatc aaataagcca attccacctc agtcaagact ggaattccct tggccaaagc
    36121 cttttcaatc atgggattgt tgtaggggat acctggattt ttcaccataa gggcaaactc
    36181 ttcatccaag agttccaaag gatggccacc tgtaatgacc ttgatccctt cttccagcaa
    36241 actttgggca gctggattgt cctcgaaagg tttcccatca tttactgtca caatggcacc
    36301 tagcttgtcc aacaaacgag ctgcagattc accagacttg gccaaaccta aaacaaggac
    36361 tttcttattt ttaaattgat ctattacttt catgtctcga actccatttc tactcctact
    36421 attttaccat ttttatggaa ataaaaaagc cacaaagtgt gtttgtgact ctttcttcta
    36481 actgaatctt accatatcat ctatgtgata aatcggtaac tcgaatgacc tgatccactt
    36541 gttcccaaat aagaggattg tgggtcgcaa taataatggt ccgattcgga ttttttaaag
    36601 attctaggat ggaaagtaat tcctcagagt ttttggggtc taaggaagtg gttggttcat
    36661 ctgcgaggat caaaggtgga tcctttaaaa ttatcttcgc taatgcaaca cgttgtgctt
    36721 ctcctcctga taactcaaat ataggttgct tcaaatccaa ataagagagg tttacacagt
    36781 ttagagcttg tttcatcaaa gagattttct ctttttcctt caacttttta ccaactaaac
    36841 ccagattgag attctctttg acggtttggc tttcaattaa gccaaaatct tgaaataagt
    36901 atcccaagta atctctaaag aaaacagaag gcttgatgtc cttaagagaa gtaccatcat
    36961 agatgatttg tcctttgtca tatggctcta atcgtccaat catattcaag aatgttgtct
    37021 taccacagcc acttgtaccg attaaggcat aaattttccc accttcaaaa tgaagatttg
    37081 tatctgaaaa tagctgacgg cttccaaatt ttttagatat attctttagt tcaatcatcc
    37141 tattttcctt tcataattgt catagaaaca cgagattctt tctgcgcttg acggtaaagc
    37201 gtcagaactg cactagctag aaagactaat aaagtgagca agccaatcac caagtctcga
    37261 ctgcttaaaa taaagagact agcaccaaat acaaaactgg caaattgact aaccatatac
    37321 tgagcatgtg tttcaaaaaa tcgtaaacct gaaattcgtt taatcaaaat atctcggcgg
    37381 aattgctcga aatatagaag attgacagaa taaaatagta ataaggaact agctatcccc
    37441 acaatagctc ctaagattaa agttgctgtt tcagtttgaa cttcattata acgagttaga
    37501 taaacacttc ttccttcttt aagataggat acttgctcat aaattccagc tttcttcaag
    37561 agttctagcc cactctcata tcctttgata aagagttgtt ttccagcatt gatagaccaa
    37621 ctagataagg atataaaact atcacctgta gaagtcggcg tgaataccac taaaatcgga
    37681 tcagtcaaat actgagtaga tacgggattc tcaccgttat tataaacaaa ccgcttttct
    37741 cccattgaaa gataactaac gtgcgctttc atctcataat ccaaaggagc acttgcctcc
    37801 tcaccagatt ttccataata actcaatctt tcttcaaaaa ctttcttaag ttctgcttct
    37861 cgagagcgca aatgttctgg gagcaagagg ataaactcac ctttttggag atgggctaac
    37921 ttctgtttgg tctcagcatc taccacgacc ttttccttgt ccaaataact gggactaaca
    37981 tagagcgtat tagcatctgg actataggta tccagtgtct ctccctgttc attttttcct
    38041 tgtggattgg caaaatggag cagattatcc tttacataaa gagcttgttc ttcttcgatt
    38101 gcttccttgg caaaggcata ccacttgctc tgattttctg tatcttttcc tctatcacct
    38161 aagccaaaag aaatttgata atagtctgct ctatcctgcc atgcttgttt tgaaatttca
    38221 agttctttca atcgttggta agacatcaaa cctgtcttaa cagcgtagcc tactgtaaag
    38281 acagcaacca actgacacaa tagggttaaa atcatcaggc gtttaagggg taatctcccc
    38341 ttaataacgg gaactaatgc tttgtaactc aaactcatta gataaagaag cattagtaaa
    38401 attgaaatcg ccaataaaaa caacagatag aaactaatcc caaaaccata ggtggctaac
    38461 aagataggat aaaacaaacc ttgactaaaa agaacgactc ccccacctag gaaggaaagg
    38521 agggctgata gaaggagcca tttgatatca gtagataaag aatgccccat gatggataag
    38581 agagtctgac cagaaaagag ttttatacct gctgctctca tttccttaat ccgagtgata
    38641 atcactaaag caaagaaaga taagccaaat attgctaaac taattaaaat aaggggattt
    38701 agtaatattc gaaaagcaag aaaatagggc ggtatctttc ggtcagcact tgctttataa
    38761 cccaaatctc ctaatttatc ggcaagcttt tctttcgtca aggagcctga caaaaggaga
    38821 taactattta gcggatcact acgttcacga ctttcttggc tagcttcttg gaattctttt
    38881 ggtaaagttc cctgaccata agttgcataa gtaaagtgag tcgtcccatc cttactcggc
    38941 tctacaattc ttctagctat taaactctgt tctgagtttg caaaattctc caattcctgt
    39001 tcaaatacct cacgcgtcgg ttcctgagta tcttttttga cacgaagtaa agaaacggaa
    39061 tcatagcttg catataaata ttgtggcgca cgtaagacaa taatccaagc aaggaagaag
    39121 ctgagaaaaa aagttgataa taatatgaat agtttcttca tagtagactc cttgtaaaca
    39181 aaattccccc tgtaatttct tacaagggga acgatttaaa tcaatgaacg attagtcata
    39241 atcacagtaa aatgctactt gttctcccca tttagtccaa atccatgcat aggaggtttt
    39301 tccagcagaa gcttctcctt tatctgaatg actattccat ctacttacaa gagaagaata
    39361 atgatatttt ttaccatgat agtaatttga aaaagcccaa ccacctcctg aaccttctcc
    39421 atacgtccat actcctccat ctggatattg tacagcagct gatgcagctc ccaataatgt
    39481 aaaacttgaa ataagagcta gagcaagtaa tctatgtttt ttcgttttca ttttattttt
    39541 tctttcaaaa aaagcacacc ttgagcaaca atgcaacaaa ataaaccctc ctctctcttt
    39601 tgttgaaacc gctttcttat gtgataaaaa tatcattttt attatttgtt gtcaaggaaa
    39661 aaatcgaatt ttttagatat tttactacat tgcctctatg aataatatta tatagtagtt
    39721 ttattttaaa ataatatgca accagtacta accaaatata aaatagatgc cattaacgaa
    39781 ttttattcaa gtttttccca ttcatactat ccaagcaaaa gagatgatgt tatagtacaa
    39841 aacaattcaa actattgtaa aattcctagc aaaaaagaga gccaaaactc tcttttttat
    39901 cttcttttac tttttttgac tggcatgagt gtaatgtctc taacactaaa gtaagctagg
    39961 atcaacatgg ctattgctag gaatatttct gttggtaatt gaaaaatttt cagaaaagat
    40021 agaaccaata aaatcaagag tgccactaaa atacatacca tagcgacgat attgactgtc
    40081 cctttaatgc tttctggtgt cgcaaataca tagagtagga gcagtaaaat tcctaggact
    40141 aaatagacca tctttctctc tttctagctc ttattcagct gattttttct tcttgttagc
    40201 tttctcacgc tctgctttgt taaggatttg tttacgcaaa cggatagact caggcgttac
    40261 ttccatgtac tcatcgtcgt tcaagaactc aagagactct tcaagtgtca agatacgagg
    40321 cgtcttgata acagctgttt ggtccttagt agctgaacga acgttggtca tttgttttgc
    40381 cttcgtgatg ttaactgtca agtcattttc acgagagttt tcaccgatga tcattccttc
    40441 ataaacctca gtacctgggt tgacaaagat cgtaccacgt tcttcgatag acatgattga
    40501 gtaagttgta gccttaccag catcgataga aacaagggca ccacggtgac gtccaccaat
    40561 ttcccctgga atcaatggca agtattggtc gaaggtatgg ttcatgatac cgtaaccacg
    40621 agtcattgac aagaactcag ttgagtatcc aatcaaacca cgcgctggaa caaggaagac
    40681 caaacgagtt tgaccattac cagttgaaat catatccaac atttcacctt tacgttcaga
    40741 aaggctttgg ataacagacc cttggtattc ttctggagtg tcgatttgta cacgttcaaa
    40801 tggttcacat ttaacaccgt cgatttcttt tacgataact tctggacgag atacttgaag
    40861 ttcatagccc tcacgacgca ttgtttcgat aaggattgac aagtgcaatt ctccacgtcc
    40921 tgaaacagtc catttatctg gtgaatcagt tgggtcaaca cgaagggaaa cgtctgtttg
    40981 caattctgcc tgcaagcgtt cttccacctt acgagaagtt acccatttac cttctttacc
    41041 agcaaatggt gagttgttga ccaagaaagt catttgaaga gttggctcat cgatgtgtag
    41101 gattggaaga gcttctactg catctgtcgg agtgatggtt tcaccgacaa agatgtcttc
    41161 catacctgaa acggcaatca agtcacccgc tttggcttct tggatttcac gacgttccaa
    41221 accaaagaaa ccgaagagtt ttgtaacacg gaagttttta gttgtaccgt caagtttaga
    41281 aagggtaact tggtccccaa ccttaactgt accacggaag acacgaccga taccgatacg
    41341 tccaacgaag tcattgtagt ccaaaagtga cacttggaac tgcaaaggct catctgagtt
    41401 atctactgga gctgggatat ggtcgataat cgtgtcaaag attggtgcca tagtcgcttc
    41461 ttggtcagct ggatcatctg acaatgaaga agttccgttg atcgctgaag cataaaccac
    41521 tgggaaatca agctggtcgt catctgcacc aagctcgatg aaaagttcca agacttcatc
    41581 cactacttct gctggacgag ctgatggctt atcgattttg ttaacaacca cgattgggac
    41641 aaggtcttgt tccaaggctt ttttcaatac gaaacgagtt tgtggcatgg ttccttcata
    41701 ggcatctacg accaagacaa caccgtcaac cattttcatg atacgctcaa cttctccacc
    41761 aaagtccgcg tgtcctggtg tgtccataat gttgatacga gttccgttgt aagcaacggc
    41821 agtattttta gcaaggatgg taatcccacg ctctttttcg atatcgtttg agtccatagc
    41881 acgctctgcc aattcagtac gtgcatcaag cgtttctgat tgtttcaata attcgtcaac
    41941 cagggttgtt ttaccgtggt caacgtgggc gataatcgca atgttacgga tatcttctct
    42001 taattttgtc atgatttcct ctataatatt caaaatttat tttctaactg aacgattata
    42061 ccataatttc aaataaataa cataactcaa gcaagtgtaa atgttttcac tccgcttttc
    42121 ttttcacgtc aagccttttc aaagcaagcg acttatgata agataggcac agtatgcgtt
    42181 tagataattt attagcccaa gaaaaagtta gccgaaaggc catgaagcaa gcactcctca
    42241 gaggggaaat tctagtcgat ggttgcccag cccgatccct agctcaaaat atcgatacag
    42301 gactacaaga actccttttt caggatcgaa tcattcaagg ctatgaacac acctatctta
    42361 tgcttcataa gcctgctggt gtcgttacag ccaacaaaga caaggaactt ccgaccgtca
    42421 tggacctgct tccatctgac atccagtctg acaagctcta tgccgttggc cgactggacc
    42481 gagatacaac gggactcctc ctcttgaccg ataacggtcc cttgggcttt cagctcctcc
    42541 atccccaata tcatgtcgat aagacttacc aagtccaggt taatgaactt ctaacacctg
    42601 accatatcca agcctttcaa aagggaattg tctttttaga tggtactgtc tgtaaacccg
    42661 caaaactaga gattctatct gcaagtccct ccctcagtca agcctctatc accatttcag
    42721 aaggaaaatt tcatcaaatc aagaaaatgt tcctctcggt tggtgttaag gtgactagcc
    42781 tcaaaagaat ccaatttggg gacttcacat tgaacccaga tttagcagaa agtaactacc
    42841 gccctttgaa ccaaaaagag ttacaaatca ttaaaaacta tttagagatg agtcgataaa
    42901 acaaaaaaag ctttaaaact aaagcttttt tcttttattt accgaaaaat taaggcgatt
    42961 gctacaatcc agttaactac agaaatcaca attcctaaga tattaagaat cttttctatt
    43021 ttatagtcta attgtgactc tttttggtat gaaatagcca agaccaatcc tatgataccc
    43081 aaaatcaagc ctacaattgg aaataacaaa ccaagaataa tcgacaagat acccacaaaa
    43141 agtggatttt tcttcttttc tttcatgttc taagaactct ttaaatttta tacaaattaa
    43201 ttatactata aaacaatagc ttcatcctat cattcgacta atttggaaat aaggttagct
    43261 agtcttcact ttccctttcc aagaatccaa gccataagaa aggatataaa tctcagaaaa
    43321 accttgtttt ttcaagtaaa gagctgcatt tgtaactcgt tgcgcacgtt ggttctcgta
    43381 gagaaggaca ggtttatctt tacgaagggc tgcaagacta gttttcaact gacttgaagg
    43441 aatattgcgt gcaccaagga tatgttttct gtggaattct gctgggtcgc gcaaatcaat
    43501 caattgaccc gtacgaatca aggcttcaaa ctcctcattg tccacaattt tagccgcacg
    43561 acgaatacga agatagttaa agcccatcca cgccaacatt gctagtataa gtgcccacaa
    43621 aatccaagta accattagtt cttttctcca tttttctcaa tataatccaa ttctaccttg
    43681 tgctctctgc gaagaactgc ttctgcctct agatagtcta atttatccat caaccctgca
    43741 tcgtaaatcc gagatagttc caacttcatc agttcaatat catataagcg ttttcccatg
    43801 taaacaataa taccaaatcg tttgaggaat tgctgcacat catagaatgt tttcataaga
    43861 ctcattctag caaaattttg tgtttttttc aagaagagac tcacacaatg ctccttattt
    43921 tcctatcttc tttggcgatt ctaaggcaag tgtggtacaa taaaaacatg agaattcaac
    43981 aattacatta tattatcaaa atcgtcgaaa ctggctctat gaatgaggca gccaagcaac
    44041 tctttatcac tcagccaagt ctttccaatg ctgtgagaga tttggaaaat gaaatgggca
    44101 ttgagatctt tatccgcaat cccaagggaa tcaccttgac ccgtgatggg atggagtttc
    44161 tctcttatgc ccgtcaggtt gtcgagcaaa ctcagcttct ggaggaacgc tataaaaatc
    44221 ctgtcgccca ccgcgaactc tttagcgttt cgtctcaaca ctatgccttt gtggtcaatg
    44281 cctttgtctc tttgctcaag aaaagcgata tggagaaata cgagcttttc cttcgtgaaa
    44341 ctcggacttg ggagattatc gacgacgtca agaacttccg cagtgaggtc ggggtcctct
    44401 tcttaaacag ttacaaccgt gatgttttaa ccaagatgct ggatgacaat cacctactag
    44461 cccaccatct cttcacagcg caaccgcata tctttgtcag caagaccaac cctctggcaa
    44521 agaaagacaa ggtgaaactg tctgatttgg agaatttccc ttacctcagc tatgaccaag
    44581 ggacgcacaa ctccttctac ttttcagaag agattctttc tcaagaacac cacaagaaat
    44641 ccattgtggt cagtgaccgt gccaccctct ttaatctctt gattggtttg gatggttata
    44701 ccattgcgac agggattttg aacagcaacc taaacggaga caatatcgtt tctatcccac
    44761 tggatattga tgacccgatt gagctggtct atatccagca tgagaaaacc agcctatcta
    44821 agatgggcga acgctttatc gactatctac tagaagaagt tcagtttgat agttgagaaa
    44881 tgataagaac caatatgtag gctagcaaca acctgcacat tggttctttt tacttataat
    44941 taaaagtttc ccctgccaac ttatcagcta gcttgggaaa gagagtataa aacttatggg
    45001 ctaggttcaa caaaatcggg agattgagtt ctcgtttatt ttttcctata atcttgacaa
    45061 tctttttagc cactgcatct gcctctaaga ggaagcggtc aaccgattta agataagttc
    45121 catctgggtc agcttggtca aaaaatcctg ttcggattgg acctggattg actgttgtca
    45181 catagactcc atagggcata agttcgagtc gcagagcatt tgaaaaacca atagccgcaa
    45241 acttggtcgc tgagtaaaga ctagacttgc cagtagctat tagacctgcc atgctgacga
    45301 tgttgatgat atgccctttg ctgctttcct tcatacgagc cgcaaggtga cgagacagat
    45361 tcatcagggc aaaggtattg acctcaaaca tctggtgaat atctttatca gcaatctggt
    45421 caaatccctc aaaaatcccg taaccagcgt tgttaatcaa gacatcaatc ttgccatagc
    45481 ggagataaag atcagttacc agagcttcta gggctgaatc gtcggtaata tcaatttcaa
    45541 tcaattctgc atgggaataa tttccgtaga gttgggctaa tttttcctta tttctaccaa
    45601 gcaagatgag ttggtcattg ggcaggagtt tgaccatttc ttgagctaga ccaccgctag
    45661 ctccggtaat gagaatagta ggcatactta tcctttctgt gactgctaga tttccacttc
    45721 ttccaagtct ttgaccacat ggacattttc aaaaattgtg gcagcgtcct tcttgagttt
    45781 gcttatatct tttgagagga aacgggcact gatatggttg agtaggaggc gtttggcacc
    45841 tgcttctacc gctacttgtg cagcttgcat attagttgag tgaccatggt tacgagcaat
    45901 tttttcatca cccttgccat aagtggactc atgaactagg acatctgcat tgacagccag
    45961 acgcacactg gcatccgttt ttcgagtgtc tcctaaaata gtgataatct tacctggacg
    46021 tggcgctgag atatagtctg ctgccttgat ttcagttccg tcttccaaaa caagatcctg
    46081 gccgtttttg attttaccaa aaagcgggcc gaacggaaca ccagcagcct tgagtttttc
    46141 agcatccagc gtcccttcta gatccttttg catgacacga tagccaacac agaaaatagt
    46201 gtggtccagc tcctctgcat acacagtgaa tttatcggtt tcaagaattt tacccagaga
    46261 atcttggtca aactcatgga aatgaatgcg gtagggcaga cgagaacctg acacacgaag
    46321 gctggttaag acaaatgact tgattccttg aggtccgtag atttccaaat ctgtctgctc
    46381 ttcattggcc tgaaaggcac ggctagaaag gaaacctggc aaaccaaaaa tgtggtctcc
    46441 atgcagatga gtaataaaga ttttgctgac cttacgtggt cgaattgtgg tttccagaat
    46501 gcgattttgc gtaccttctc cacagtcaaa gagccaaact tcgttaatct cgtccaaaag
    46561 tttcagggcg agacttgaaa cgttgcgggc tttagagggc tgaccagccc ccgttcctaa
    46621 aaattgaata tccattcgat actttctaat taatcaatat ataacatggc tgtgcggttt
    46681 tccgatcgga aatagcgttt gccagaaaaa gcagcagctt cttgcaataa atcctcttgg
    46741 ctgtagcctt tgagacgttt tcgaccatca gccaatcttt ccaaatcagt caaagctgtg
    46801 agactttcta ggctgacaac ttcctcgtcc ttgacaggct tcatgtaaat cttaccagac
    46861 tcttcaaaga ctaattgatg ggagaaaatt tgcgcaattt caaagagcaa gtcatccgag
    46921 attttctcct cattttcaga gaaaatccga ccaaagccgt cactctcata acaaaaacca
    46981 aaggatttac cagacagatt aagccgaata aaaggcttat tttctagggt gaaacttggc
    47041 tcagtattgt aaagattcag ttcctgactg agttctgcaa aataatccgt cgcagcctga
    47101 ggactttttt tctgatagag ttctgcaaag taggcattaa caacacttgg cggaggtgta
    47161 ataagtgtta actgctcctg ctctgtttta ccagctagaa gctgatccag atagaccttg
    47221 tccagacttg tataacctcc atactttaga gccaaagttt taatatcagt cataaaattc
    47281 ttctaacctc catttatttt tctcggaaat gtagcctgta atcacttcgc cgtcttcctg
    47341 ataatcacgt tcttccagaa ttgcaacact ctctaaatca tgaatcttgt aggactttga
    47401 aaaaggcact cgcagggtaa atgcttcaaa aatttcctta atcttatcta gcaataatgc
    47461 ttgcaagttt tcacgactgt cctcagactt ggcagaaatg agggtatatg gcgtttgggt
    47521 aggcgtgaaa tcctccacca aatccgcttt attataaagc gtcaagtgag gaatatcttc
    47581 catgtccagg tctttcatga tggagagaac cgttttttca tgctcctcgt ggtaaggatt
    47641 gctagcatcg ataacatgaa ccagaaggtc cacatgcttg ctttcttcca aggttgactt
    47701 gaaactggac accaactctg tcggcaaatc ttggataaag ccaacagtat ctgtcaaagt
    47761 tacttggaga ttgcctccca gatgaatact cttggttgtc gcatccagag tcgcaaagag
    47821 ctcatctgct tcatactggg tcttactggt caagatgttc atgatagttg atttcccagc
    47881 attagtataa ccaatcaaac caatcttaaa agtgctagac tccaaacgtt tttctctgac
    47941 agtcgcacga tttttctcaa ccaccttaag ctggcgctcg atatccgtga tttgattgcg
    48001 aacgctacga cggttcagct ccagttggct ttcaccagga ccacgggaac caattccccc
    48061 tgcctgacgg ctgagcataa tcccctgacc aaccaagcga ggcaagaggt atttgagttg
    48121 ggctaggtgg acttggagct tcccttcatg gcttcgagcc cgcatggcaa agatatccaa
    48181 aatcaactgc atacggtcaa tgaccttaac accgagaact tcctctagat tgacattctg
    48241 ccttggggtc agacggttgt tgacgatgac agtagtgatt tcttctgcat ccaccataag
    48301 cgcaatctct tccaacttac cagagccgac gaaggtcttg gaatcatatt tttcacgttt
    48361 ttgtctgtag ctatctacaa cgactgcccc tgccgttttc gctaaactag ccaattcttc
    48421 catggagagg tcaaaactgt ccataccctg caattccaca ccaatcagca ggactcgctc
    48481 ctcttttttc tccgtttcaa tcatctaaaa actcctctat ctggcttaaa atgcggtctt
    48541 gtacaccaga ttctccaatc tgataaaagg tgacctgcat gcgattacgg aaccaggtca
    48601 gctgacgctt ggcaaaacga cgggtcgcct gtttaagact ctcacgagct tcctccaagg
    48661 tctgctctcc acggaaataa ggaaagagtt ccttatagcc aattccttta gcagcctgta
    48721 cattagggga atggtcaaac agccacttgg cctcatccaa aagcccagcc tcaaacatca
    48781 aatccactcg gtggttgata cgctcataaa gttgactacg ttcatcatcc aagcagataa
    48841 tcagcggttc atacaaaatc tcttgatttt ccaaatcctg accaaaatgg gcaatttcta
    48901 aggcacgcat agcacgacga cgattaaact ggggaatctc aaggcctgct tgctccacca
    48961 aatgggctaa ttcctcatct gaatatggct ccaaactagc tcgataagct aaaatctcct
    49021 catgaggagt ctccccacct aggtggtaac cttctagcaa gctctggata taaagtccag
    49081 tcccaccggc gataatggct agcttgccac ggctgtgaat atcctcaata gtcatcttag
    49141 cttctgaaac aaaatcaaaa gccgagtaag actcagttat ctctctaaca tcgattaaat
    49201 gatgaggaac agctgcctgc tcttctggac tagccttggc cgtcccaata tcaagtcctc
    49261 gatagacttg ctggctatct ccactaacca cttcgccatt aaagcacttt gcaacttcaa
    49321 tagctagagc cgtctttcca acagcagtcg gtccaacaat cacaattatt tttgttttca
    49381 tcttttttcc ttgaaaaatt cccatttttt cgttactatt attataacac aaaaaggtca
    49441 gtcagaaaaa tgtgacctct tgaggaggct ggctgattga gaatataaag gaggaagact
    49501 catggctaaa ggattcgcta aaggtcttgt aacaggtgtc gcaggaactg tcgctgccgt
    49561 tgcaggtgca gtatacgcat ttaaaaagaa agtaatcgaa ccagaagagc aaaaagcagc
    49621 tttcatcgaa gaaaaccgta aaaaagcagc tcgtcgccgc gtatcacgtt aagaaacaaa
    49681 agaagttggg attattctca acttcttttt tctattcttt taaatagcta ggtcaaactt
    49741 caactgtggc ttaacagggt cataatccac caactcaaaa tcttctgctt tgatatcaaa
    49801 gaaattagtc ccatcaggaa catttaaaac caagcgtggt tggcagtttg acggctcccg
    49861 acggagcaat tcctgagctt gttcaaattg attatcatag atatggaggt tgttgatgaa
    49921 gtagaagaac ttcccaacct tccagccaaa atgtttagca atcatcatct gcaaagccac
    49981 atactgcata gcgttgatgt ggtgggccac cagcatatca ttggagcgct gggtcaaggt
    50041 cgcatccaga tagatttccc catcaacacg ccgaacatca aacatggtct gaaaggcgca
    50101 cgggagcagc ccatctgttt cttcgaaagc ttggtaatcc cagagagaaa taatattgcg
    50161 gcggttccaa ggattggttt ccaactgttt gagaagctta ttgataatgt cgtgtttctt
    50221 aacaacggca ccatagcgct caccaatggt tcccgtgtct ccaacttccc agtcattcca
    50281 gtagtgaaca ttgtacttgt cattaagcac ttctaagcta tttgactggt cttggtaaat
    50341 ccagagaact tctttgatgg cggatttgat tgcaatggga cgcaaggtta tgataggaaa
    50401 ttctccttta gataagtcgt actcggaaaa ggcaccagtt acatacttgg aattagcaac
    50461 agtcccatcc ttgtacttag gacgagcctg ctctgagaaa acaccttcct ttagaatgcg
    50521 ttcaatattc tctttaaaaa tcgtatctgc ttttgtcatt tactctcacc tcattcattg
    50581 tcctaactag tatagcataa aaaataaaag aggaacatta ctaactctag gttagcattt
    50641 tcctctctca ttatcttatt gcaatacaag tgatgctgct ccgataactc cagcgtcatt
    50701 tcctagagtt gcaagagcta atttagtaga tgtgcgtact tgtgggaaag tattttcgtc
    50761 atagactttt tgaacacctt gtagaaggaa ttctcccgca gctgacacac caccaccgat
    50821 gacgattgtt gatgggttta ggattgaacc aatgttagca caagcgattc ccaagtaacg
    50881 tgagaagtta cggtaaacaa tcaaagcaag gtcgtctcct tcttttgcga gatcaaagac
    50941 agtcttagca gttacttctt ctccgttatc aatcaagcgt ttcaaggctg catcgccttc
    51001 gtattcatcg gcatagcgac gagtcaagtt gacaattcct gttgcagaag cgactgtctc
    51061 aagacagcct ttcttaccgc aagtacatga gattggctgg tcaaagtcaa cagtgatgtg
    51121 acccaactca cctgctgcac cagcaacacc gtgaagcaat ttgccttctg cgacgatacc
    51181 gccaccaaca ccagtaccga gtgtcataaa gacaacatct ggttggttat caccagcacc
    51241 catccagcgc tcaccaagag ctgctacgtt ggcatcatta tcgatgaaaa atggaatgcc
    51301 caaagctttt tcaatctttt gtttgattgg ttgaagggtt ttccagttca agttgtaggc
    51361 accgataaca gtccctttgt cacggtcaac cacacctggt gatcccattc caatgccttg
    51421 gaagtccgct gctgccaatc caagcaagtc caaacgatgt tgaatagact caatcatatc
    51481 atcaacgata tgacttccct catccaaaat gttggtcttg attgaccatt ttccttggat
    51541 ttctcctgct gttgttaaga ttgcaaattt gatagaagtt ccaccaaggt caatcccaat
    51601 aatcttttga ctcattatat tctccttttt cattgtgtag taattgaaaa tgcttacagt
    51661 actagtatat caaaatccat tcacttatgc aaaggtttgc gtaaatgaat tataaggaat
    51721 tttttcgcct accagtatct gttaaccatc taaatgatca atggcatatt gagctgcatc
    51781 atttgaaaat ttatcaaaat cagaagttaa ttgtctatac atacgttttt ttgacatgtg
    51841 gaataacgaa ttataacttt ttgcctttcc taaagcagca gaatattcac tattgctatc
    51901 attactagaa gaagctgtac ttgcttgacc ttccttccaa actccgtcag cgccaacata
    51961 ataacgtcca ccatcaaccc attcattgac agccatttta ccatccgatt ttagatagta
    52021 atttccttgc catgtactat aagcataaga accatctgat gtcaaataat accaagcttg
    52081 ataggtggca tcataaaccc attcaccttt agccatttta ccatctgatt tcaaatagta
    52141 gtttccttgc catgcattgc gagcatatga accatctgat ttcaagtaat accatgcttg
    52201 gtaagaagaa tcataaaccc actcaccttg tgccatttta ccgtttgatt taaggtaata
    52261 agctccttgc catgcatttt ttgcataaga accatctgat ttcaaataat accaagcttg
    52321 ataagaagag tcataaatcc attcactctg tgccattttg ccatcagctt tcaggtaata
    52381 gtttccctgc catgcatttt tcactagatt tccatttcca tcaaaatagt accaagaacc
    52441 gtcctgctta acccaaccac ttgctgtgga tgaagttgta tcagtttgag ttgtagccgc
    52501 ttgttttgct ttaaaagcac ccttaggagc atttttcaat tcgcaagcca caccatcatg
    52561 atcgcggtct aacttggcag aataaccagg ttctccctca tgaagatccg aatatccatt
    52621 agcccaagct tccttacagc tcgaaaaatg gatgttttct tccgccaaaa ctggttgtga
    52681 aaacaaggct aaaattggca acgtcaccag actcattttt aaaaatagac gtttattcat
    52741 ttctttctcc cataattatg atatcgattt caatattatt ttatcaaact tatttcagca
    52801 attcaaggaa acttctggtc ttttctacaa actcctttgg ttttgcctta ttcaagacat
    52861 gagggccatc aggaatgatc tgaaactgcg aatctgttaa cagtctatgg agagctttca
    52921 tagaactaag attcggttta tctttgctgc cacaaattag taaggttgga taggagcaag
    52981 tccctgctat atccgttaaa tcaagtgtct tcaattcctc agaaactccg accataagag
    53041 tcttgtctgc tccctgtttt tcaaatactc ttttgggaag tagtttaaaa atcagcaact
    53101 gaagataaaa taggatattc cctgctaatt taagcgggca tcctgacaga atcaaagctc
    53161 gaagatttgg taaatcgtaa ctggaaagtt ctagtgtcag ggcagcacct aaggacaatc
    53221 caatcaaaac aaaaggttct gtctcttgag ctaggtgctg ataaactcgc tctttagctt
    53281 gttgatagtt actaactcca gaaggaaata actcgatagc ctcagaagga taatctgtca
    53341 gtagattccg aacttctttc caagactctg ctgactgccc taacccatgc aaaaatatca
    53401 atttcatcta gttctcctca aggcttagtt catacaagcc tctcactgca ttacagccgt
    53461 aaatagcttc tgcttgggtt aaatctgcca aggtcaagac tttctcttct acctgtcctg
    53521 tttctagcaa atactgacgg taaattcctg gtaagattcc aagtcggata ggcggtgtgt
    53581 agagttttcc agcgattttc agaaccaaat ttcctataga ggtttcaagc agttctcctg
    53641 acttattgtg gtaaatcttc tcttgttctc ctaggctcaa atgcggtcgg tgagtggttt
    53701 taaagtaggt aaaggattga ttcaaagcag cttcctgaag gcagacttgg gcctgacaaa
    53761 agcttgtact gagaggggtt aatacttgac gattgacttc tatctctcca gatttgctaa
    53821 ggctgattcg caagcggtaa tctcgattag cttcacaatc ctgacactct tcctcaatct
    53881 tgtgtcccaa gtcttctgca tcaaaaggaa aagcaaaata acgactagct tttctcagtc
    53941 tttccagatg ttgatcttca aacagcaggt tcttctggct gatttcccct gtcgtaatca
    54001 gttggaagcg agcttgttta cgataaagaa ctgctgcctt ttgatgaacc tctcggtatt
    54061 cagattccca tgtgctatcc caagtaatcc ctccgccaac tccataaatg gcttgacctt
    54121 tgtgaagttg aatggtacga atggccacat taaaaatccg tcgtccattt ggaagcaaga
    54181 gaccaatcgt tccacagtag actccacgcg gttgaggctc caagtccttg ataatctcca
    54241 ttgtcgcaat tttcggtgca cccgttatgg aaccacaagg aaagagtgag cggaagattt
    54301 caacaaggtc cacatcctct cgcaactgac tcttgatggt cgaagtcatc tgccaaacag
    54361 ttgaatactg ctctacctga cacagacgct ccacgtgctc gctcccaact tcagaaatac
    54421 ggttcatatc attgcgcaag aggtccacaa tcatcatatt ttcagagcga tttttgggat
    54481 cctgttccaa ccaactggcc tgttcaagat cttcttggtc agttacccca cgctgagtcg
    54541 tccccttcat tggtcgtgtt gtcaactcgc gatcattttg ctcaaaaaag agctctgggc
    54601 tcatggaaat cactgccatc tcgtcatgtt ccacataggc attgtagccc gcctcctgct
    54661 ctaccaccat acgattgtag atggcaaaag gattggcact taacttttgc ttgagttgga
    54721 cggtgtagtt gacctgatag gtgtctccct gcctcaagtg atggtgtatc tgggcaatgg
    54781 ccttttcata gtctgctgca gacgtcactt cctgccaatt tgagggcaaa tcaatatcct
    54841 cataagtcag aggaataggg gaagtttcta cgctatcatg aacagtaaag taaagcaggt
    54901 actctcccag taggggatcc ttgtgaactg ctaatttttc ctcaaaagca ggtgcagcct
    54961 cgtagctgac ataccccacc acataataac cttgctcttg gtagctttcc acttgtgcca
    55021 gcaaatctgc cacttcttct acatttctcg ttttcaactc tttaataggc tgggcaaagg
    55081 tatatctctc ccctaaagtc ctaaaatcaa tcactgtttt tctatgcata ccttaagtat
    55141 agcataaaaa ggcagataca gacaaagctg atctaccttt ttacgatttt attcattcta
    55201 tgcttgtggt gcagtaaata gatcaccaga gaaaccgtct gtgtttttaa ggagagcttt
    55261 aaagactttc gatttcaaga caactgtatt tcggtatttg tctttaatac tactatcgtt
    55321 tagttccgtt aaatctttag taacagcctc atcaaacata gtcttcaact gttcataggt
    55381 tgaaatttga gtgccattaa tttcaattgg tgcaaaacct tttttagatt ttgtaagaac
    55441 ttccccatac cattgcttct tccaatcttc aaggtttgaa aattggttat tagaaacttt
    55501 cttaataatg aaatcatcac ctaatagacc gttattttct ttattggctg caccttgatg
    55561 tttgcttgaa acatagtcaa tgaacccatg ttcatatcca tagtaacccc acatacggaa
    55621 ggcgttatgt ttgaaggata gagaaccagg ggcaccttga ctcgtattac cgccataaat
    55681 accagccatc atattaacat tgacatatgc cgtaccaaag tcctctgggt ggaagacctt
    55741 attacctgga tttccgtgaa tggtcatgaa attattattt accaagtcat cgatggtttc
    55801 aaggttagtt gttttctcag cgtctatcaa atcacgcact ttgtcccatt ggtgaggacc
    55861 acttagttta tttctgtcca ttggtcgacg tgtttcgcga tcaattttct tgaaccactt
    55921 actattgtca cctttaacct taggaagaac agcctcagct tctgcataat cgagcatcat
    55981 catagcttca ttgtagttct tcatgtaatg gtcgatttgg tcacgtgttt gaagtttggt
    56041 aggatctgga ttataccatt ggtttccatc atttgaacgt tcaaatgcca tatttaatcc
    56101 aagtgcgcca tattcacctt gatgtccatg ttctgctgga gtttgtaaca taccttgagc
    56161 aaatgcttca agatctgtac cctgtcgatg tctatgacct cccagatatg ccattcggtc
    56221 atttacgtgg gtagtctcat gtgtaaaggc agatgtgcca tattcactta ttaaatccga
    56281 cataacaaaa tatacagcat ccataggctg tggatcagca aagatgtaag catacgctcc
    56341 atacccatac ttataatcat gatacttatc aatacgtcca aagaattcac gaataggtgc
    56401 ataatccggt ttatcttttc gatgaccaaa tctatcaggc caaccaccgg gtgcaccatg
    56461 attatcccat acaggagttg gaactacatt ttgactctta agaagtttat cgcggacatt
    56521 atcagtggca aggcgtgacc aaaaatctaa gtaattaact tgctctttag cacgtttatt
    56581 gatttcactc ttgaacgatt cacgtttttc ttctgtatct ttaccatact tttcaaacga
    56641 actaaatgag atagtattat atgttgaaat cataaataaa tgtgcatctt tcaagttcag
    56701 aagcgataaa atcatgcgtc catgttgtcc gttattaagt ccttcatata gacgatattt
    56761 tttattagca aatgcagggt tagttgacgg ttgttcaact acataagcat tattttcaat
    56821 agctttctta aaccaaacat ttatgtctgt ttcatttgtg aatagtttca tattgtaggt
    56881 caagaagtca tgtaagtttc cagaaagagt atttttcgcc accacttcac ggaaggactc
    56941 ctgtgtacga cttcccttaa tatagtcctc ttttgaacca atttctatta atcgatctaa
    57001 aacacttaca ttcttaccat aaaaatctgg tttgaatagc attaattctt taatattgaa
    57061 gttatcaaat ttcacaccgt aataacgatt taggtatgtt aatcctaaca ggacagcagc
    57121 tttgttatct tcaattttct taatcaaggc acgttttgca gcttcatctg tattcagttg
    57181 atgatcttca ttttcaacta attttgtcac aaatgtatta agatgatctt ttacttcttt
    57241 aaagctttct tctaagtaaa gattcttaat tgcattaact ctgttatccc cagttcttcc
    57301 taatcgttga taaattggat cagattgtaa ttcaattgga cttaaaatac cttcaatagc
    57361 actaattaaa tctgcacgat ctttaacaac catatttggt gtatagacga cttcaccaag
    57421 ctctgcgaca ctgtattctt ttacttgctt aacttgagag tctttaggag aaatcgtaaa
    57481 gatatctttt gtcttatctg cgtaatgaac cataatatgg tcagcatctg taaggtctgt
    57541 aataaagtca ttacctttca ttgcagtcac agacaatact tctttattca ttaatggact
    57601 atcagttgta agcttgttcc cttgattcac aatccattct ttgttgtaga acggttggag
    57661 tttttcaaca ttacgataaa caagctcacg atttgcatta taatcttgaa ttgttttgta
    57721 ttcttcatca cgtaatatac ggcgattcaa cttatcaacc aaatgctcag ttacttcaaa
    57781 tgtatcagca gtgataccca tatccttaat tttcttatca gcttctacct gtgaaatttc
    57841 tttaatttta gacgattgtt tatgggtttt atctccagaa ctcacaccga taactgttgc
    57901 attattaggt ttaatccaat tgcttacaaa ttcatcatcc atatcattag aaccaaagaa
    57961 aatatcacca cgcttaacat tcactaagct gatattgtta tcaatggttc cccaaggcca
    58021 gtctttacca attaaaccgc ctacatcacc tctagcaaca tcaatagtac ctttggctac
    58081 agaatttctt acattagacc aagcaccaac atctcttgga ttaaaatcat gagctaaatg
    58141 tcctactata gcacctgcac gagtatttaa acctttaagt tcaacatctg cataagcttt
    58201 atttaaattg cctcgataaa tctcagatgc aatcccagcc aagttccacc ctttatcacc
    58261 aacagattga acttttccga taaaagcaac attagtcata atacctgcat catctaattt
    58321 atccaaaata cccgcaacat tgttattacc aacgatagta cccgttactt taatattttc
    58381 aacagttgca tttttcactg tttgagctaa tgaagctaat tgatttgccc aaggcatatt
    58441 aatattaacg ttaattaaat taatattttt gatagaaccc ccttcaactc tatcaaataa
    58501 tggacgagca gtgttatgaa tggagaaatg cttaccatca acacttgtta agtgacctgt
    58561 aaatttacct gttacatatg atttacttgg tgtaggtaca tttgttgcat ttaaatccga
    58621 tcctaattta aactcaccgt taggattttt ctgcatagca tctactaaat ctttgaagtt
    58681 atagtaaacg ttattttgcg atgctttggg tttctctatg taataagtgt atgtttgact
    58741 caaactatta tttgaatcac gttggattaa atcaggagct gaagcagtaa ctttaaataa
    58801 ggatgtctcc tcctcagtta cttcctctat attagtaatg gcaagccttg ttactttatt
    58861 atgattagtg gtaattttta gataatatga cgttagattt tctggaacag tttctagaag
    58921 gctactatct gtttcatttc cattctcatc cactttcatc aatcttgttt ctttaatatc
    58981 tttaatctca acttttttaa ggtctaactg aacttcttta tcttctaata tttcagtttc
    59041 ttcaccgtta cctcgatcat agaccatggt tgtggatagt gtataacctt gataatattt
    59101 caagttgtct aaagtagctt gtaagttatt ttcttctacc gttacttctt taacaactgt
    59161 tccagtatta tcttttagag ctactttaat cgatttaatt tctactccag ctggtttagt
    59221 caatgtataa ctagctgtcg cactcttctt caagacatct ttatctgttt tagcccattc
    59281 caaggttggt ttctctaact cttttgtgcc attcttaata attttgtctt gaggtttttc
    59341 aatcactgtt tctgtgatag taggagcgtc acttgttttt tctccgcgaa ttgttttata
    59401 ggtttcagta atttgtttct tatcgtttac accttcttga gttacttgtc ttgttccgcg
    59461 ttttaaagtg tcatcttctt gttcttttgt ttcaaaagga atgatttctt ctcttgtctc
    59521 aaccgttgtc ccttcaattg gttttgtacc acggattacc tgttgattta caggctcctt
    59581 ggtgacttcc gtactggttg aaagaacttg gtcagtttta acccctccta ttgttttata
    59641 ggttgttttt gtaacttgac ttcctttttc accatttcgt aggacagttt cttcgtccgt
    59701 gtacttggtt gggtcctcag tcgtttcagt tttatagtca agttctgtag ttgattcttc
    59761 aacgagtgtt ccttcagtca ccttatactc aggtaattgt tctggaacaa gagcctcacc
    59821 cacgtaatct tcttcttgcg tccccttagc tgttttagtc tcctcttttg gttctacagt
    59881 ttcttcagcc ttggtatctg gagttgactc ttcttgtttc ggtgtctctt ccgctcccct
    59941 atcttcttta ggattgtctt cttgtgatga ttcttttggt gtacttggtt gctcagcttg
    60001 tgtaggttgc acgggttgtt ctgggacttt tgcttgttct actggtggtt caacttttga
    60061 ttcctcagct ggtttgtctg atggttgact ttctggctta actgctactt tttcctctga
    60121 ttttgactca acttctccac ctacttcttc aactggagct ggttctgctg aatcttcttt
    60181 cccctcttct actttaggaa gggtgtcgtc agtaggtttt acctccgatt ttggttcttc
    60241 ctttggactt tcttctgttc taggtgcttc ttcttttgga gtttcctctg tctctactac
    60301 ttggttttct gtcctagctt gctcctgatt tgttgttgat tgaggagtct caacttcgac
    60361 tacagtcacc tctccaggtt ttgctgaggt ttcttctaaa acagtgtcca agccaagcgt
    60421 tttgaggatg tcacctgata gataaccaac atagcgatag ccatccattt caacaacacc
    60481 ctctcgacta gccagcgcta aggtcgcaac tgggtctaca gcccctgcac taggaagaac
    60541 taccaatccc atagctccaa ctagaaagac gctagcaatt ttctttctct tgtagattaa
    60601 aagcaagctc ccaacagtca gcaaaccaaa agctgtcaaa acagatgctt ctgtccctgt
    60661 ttgaggcaac tgatcttttt gatacaccaa accatataca acttcattcc tgtcaggctt
    60721 tcctgtctga attaaatctt tagcttcttg tgaaataatc tctttattta catagtgata
    60781 ggtagctgcg tccactacag aaggagccat caaaaggctt ccaagaaata cagagcctac
    60841 aactccctta atcttacgaa ttgaaaaacg gtctttttta aacactttca tctcctttat
    60901 tcattctcaa gactttctaa tagcatcttg cggatagtgc gcacgcgcac ctccgattaa
    60961 ttttggacga ctagccagtg ccgttacatg ggcatgacca atctctctca aaatagggcg
    61021 aatcggaacc tgaacatgct tgacatgcat gccaattgca gtgtctccga tatccaatcc
    61081 agcatgagcc ttgataaatt caacctcaac tggatcctgc ataaacttaa aggctgccaa
    61141 ctgccccgaa cctcctgcat gaagagtagg atggacactg acaatttcca gatcaaactg
    61201 ctctgccacc tgacgttcaa caacgagagc ccgattgaca tgctcacaac cttgaactgc
    61261 taaatggata cctctactac ctagaatacc caagatagtc tccactatca gctcaccaat
    61321 ctcttgactg gattctttcc caatctgacc acctagcacc tcactagaag atagacctaa
    61381 aacaaaaagg accccctgct tcaaattggt cttttctaaa acatcttcca ctacctgacg
    61441 tgtttctctt tgaatctgtg tctcgttcat ctctgttacc tctgttgtca ctcttctatc
    61501 ataccgtttt ttcttgtttt tagcaagata gacaacctat aaagtctgcc caattacgca
    61561 taaaactccc agaattgact gggagttagc tagtttctat tctatttata tatatttcaa
    61621 ctttcgttcc tttttggggt ctagaatcaa tcttcatctg gtaattggct ccaaaatgaa
    61681 gtttgagccg ttgatcgaca ttttgaagac caactccccc acgtttgagt tgactttgac
    61741 tactatcacc agcatcttgg aagccaacgc catcatcctc aatacggatg accaatcccg
    61801 aatcctgttt ctggacagaa agtttaatat ggccctgacc ttccttttcc ttaatgccat
    61861 ggtaaagagc attttctaca aggggttgta ggaccagctt gggtaagact aaattatcaa
    61921 aggcaacatt ttcattaatt tcgtattcca gcttatctcc atagcgttgt ttctggataa
    61981 agagatactg gcggacatga ttgatttcgt cagagagaca aatcaagtcc ttgccttgat
    62041 tgagcgccaa gcggaaatag gttgccaagg acttggtcac ctgcaccact cgctgactat
    62101 catgaaattc agccatccag atgatggtgt ccaaagtgtt atagaggaaa tgtggattaa
    62161 tctggctcga aagggcttga agttggtact gacgggtcgt ttcttcctgg ctacgaatag
    62221 ctaccatcaa ctgatcaatc tgatccaaca tagcattaaa ttggcgagtt acttctctca
    62281 gttcataggc accaacttcc ttggcacgaa gattttgagc accagaagca atttccaaca
    62341 tggtttctct caaatccttc aaaggagcaa tccagcgttt aagactgaac cacactaagc
    62401 agagacaaac aagaagagat gtgacactgg ccccaagcaa ggtccacaag agctgactcc
    62461 gaacctggtc taacttttcc aatgatgaca cgccaagtac cgtccaatca gttcctgcaa
    62521 tcttctcttg actgacgtag gatttgtgac caggagtata accctgacct gtctcgatgt
    62581 agggtttcat agcctccatt ttgctagacg aactataaac tgtgtgttga ggatggtaga
    62641 caaattcatg gttttcattg ataatgaagg caaagccctg ctgccccaac tggagttgat
    62701 tgagataggc ttccagagtt tcataagaaa tatccaaacg aagcacacca agattggctc
    62761 cctttgcatc aacaagttct tgagtgacag aaatgaccca ctgactatct gatttacgag
    62821 ctggagtcaa aacaggcata gctccctgat gaatagcctt ttggtaccaa tcctcagcca
    62881 tcatatcaga ggaagttttc atctgcacac tgtcatctgt agaaatgacc tgaccagatt
    62941 tggtcaccag cacaacagtt ttcaagtcct tatctgactt caagatggtc aaaaacaaat
    63001 ctcggattcc ctcgaccttg tcttgactgg gattctcagc ataggccaga acatccgtct
    63061 gctgggtcaa accagtcgag gtggtttcta gttttttgat ataagactga ataaagtggc
    63121 tagtctggct gatggtcgtt tggctgttgc cctcaatggt ggcctcaatg gctgaagaac
    63181 ttgattgata gtagaaagtt ccaaccagag ctaggagaat gagaaagacc agaaagatgg
    63241 aaataaccat tctaactaaa agagaagaac gcttcatcgg tcttctccct tcttaaactg
    63301 acgaggtgtc acacctgcaa tctgcttaaa acgttgggta aaatagttca tatcttcaaa
    63361 accaaccttc tctgcgatct cataaatctt cagatctgta gttaaaagca agagcttggc
    63421 ttgtttaaca cgttctctca ccagataatc ctgaaaaggc aagcccaact ctttcttaat
    63481 caaggaactc agataggtcg gactaaaacc taagtcactg gctaaagact ttaaactaaa
    63541 ttggctatca gccagatgag actggatttt ctgggccatg tttccttcaa acctattagt
    63601 caataaatct tgtaactgct cttctttctc ttccttgtct agtttttgtt tgattttccc
    63661 caacatttcc tcaatatcct gacgagaaaa gggtttgagc aggtagtcgt ccacacctag
    63721 tttgacagca gacaaggcat aatcaaaatc atcgtaacct gttaaaaaga ccaaatgaac
    63781 ctgaggatag gtttctcgta ccagactggc caactggatg ccatttagat gaggcatgtt
    63841 gatatcggtt aaaatgatat ctggcacctg cttttggatc aattcccaag cctgccttcc
    63901 attttcagcc tgaccgatga tttccatatc gtaggctgct acattgacca gtttagtcaa
    63961 accttgtctt accagatatt catcttctac gattaagatt gtgtaggtca tgctctgctc
    64021 ctttaccact tactagtatc agtatagcaa aattctcctc taactgctta ggaaagacct
    64081 cttatactca ataaaaatca aaaagtaaac taggaagata gccacaggtt tctcaaagta
    64141 tagctttgag gttgtaaata aaactgacga agtcagatca aagtatagct ttgaggttgt
    64201 a
//
LOCUS       DAVAZV010000005        51752 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVAZV010000005 DAVAZV010000000
VERSION     DAVAZV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51752
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.005"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..151)
                     /locus_tag="VQT46_000290"
                     /pseudo
     CDS             complement(1..151)
                     /locus_tag="VQT46_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            137..622
                     /locus_tag="VQT46_000291"
     CDS             137..622
                     /locus_tag="VQT46_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET2370390.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDYALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            706..1413
                     /locus_tag="VQT46_000292"
     CDS             706..1413
                     /locus_tag="VQT46_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2370391.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1414..2745
                     /locus_tag="VQT46_000293"
     CDS             1414..2745
                     /locus_tag="VQT46_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET2370392.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSALKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2912..3787
                     /locus_tag="VQT46_000294"
     CDS             2912..3787
                     /locus_tag="VQT46_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET2370393.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3905..4768
                     /gene="pstC"
                     /locus_tag="VQT46_000295"
     CDS             3905..4768
                     /gene="pstC"
                     /locus_tag="VQT46_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET2370394.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4761..5576
                     /gene="pstA"
                     /locus_tag="VQT46_000296"
     CDS             4761..5576
                     /gene="pstA"
                     /locus_tag="VQT46_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET2370395.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5578..6330
                     /gene="pstB"
                     /locus_tag="VQT46_000297"
     CDS             5578..6330
                     /gene="pstB"
                     /locus_tag="VQT46_000297"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET2370396.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6345..6995
                     /gene="phoU"
                     /locus_tag="VQT46_000298"
     CDS             6345..6995
                     /gene="phoU"
                     /locus_tag="VQT46_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET2370397.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLADLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7063..7488
                     /locus_tag="VQT46_000299"
     CDS             7063..7488
                     /locus_tag="VQT46_000299"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2370398.1"
                     /translation="MNNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7668..8045)
                     /locus_tag="VQT46_000300"
                     /pseudo
     CDS             complement(7668..8045)
                     /locus_tag="VQT46_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            8257..9273
                     /locus_tag="VQT46_000301"
     CDS             8257..9273
                     /locus_tag="VQT46_000301"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2370399.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9295..10194
                     /gene="galU"
                     /locus_tag="VQT46_000302"
     CDS             9295..10194
                     /gene="galU"
                     /locus_tag="VQT46_000302"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET2370400.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDKTTDMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FQILENQAPGAGNEIQLTDAIDTLNKTQRVFAREFNGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(10266..10943)
                     /locus_tag="VQT46_000303"
     CDS             complement(10266..10943)
                     /locus_tag="VQT46_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET2370401.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            complement(10927..11466)
                     /locus_tag="VQT46_000304"
     CDS             complement(10927..11466)
                     /locus_tag="VQT46_000304"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET2370402.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLTPKTYPKGRMDFVVYDPQQLVKTSFALLEPQ
                     GDLEVVDASQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRALSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(11478..12608)
                     /locus_tag="VQT46_000305"
     CDS             complement(11478..12608)
                     /locus_tag="VQT46_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET2370403.1"
                     /translation="MLDLIQTRRALHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFTSQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(12676..13374)
                     /gene="dapD"
                     /locus_tag="VQT46_000306"
     CDS             complement(12676..13374)
                     /gene="dapD"
                     /locus_tag="VQT46_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET2370404.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVCVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(13604..14515)
                     /locus_tag="VQT46_000307"
     CDS             complement(13604..14515)
                     /locus_tag="VQT46_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2370405.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCLEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(14580..17045)
                     /locus_tag="VQT46_000308"
     CDS             complement(14580..17045)
                     /locus_tag="VQT46_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2370406.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGVGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            17187..18443
                     /locus_tag="VQT46_000309"
     CDS             17187..18443
                     /locus_tag="VQT46_000309"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET2370407.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(18521..20584)
                     /locus_tag="VQT46_000310"
     CDS             complement(18521..20584)
                     /locus_tag="VQT46_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET2370408.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWFSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(20586..20864)
                     /locus_tag="VQT46_000311"
     CDS             complement(20586..20864)
                     /locus_tag="VQT46_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370409.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            21009..21857
                     /locus_tag="VQT46_000312"
     CDS             21009..21857
                     /locus_tag="VQT46_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2370410.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            22479..23051
                     /locus_tag="VQT46_000313"
     CDS             22479..23051
                     /locus_tag="VQT46_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370411.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAINLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(24095..26353)
                     /locus_tag="VQT46_000314"
     CDS             complement(24095..26353)
                     /locus_tag="VQT46_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HET2370412.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIDLDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINPNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(26379..27896)
                     /gene="malQ"
                     /locus_tag="VQT46_000315"
     CDS             complement(26379..27896)
                     /gene="malQ"
                     /locus_tag="VQT46_000315"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET2370413.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            28446..29717
                     /locus_tag="VQT46_000316"
     CDS             28446..29717
                     /locus_tag="VQT46_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2370414.1"
                     /translation="MSSKFMKSTAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            29828..31120
                     /locus_tag="VQT46_000317"
     CDS             29828..31120
                     /locus_tag="VQT46_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2370415.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGNKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            31122..31964
                     /locus_tag="VQT46_000318"
     CDS             31122..31964
                     /locus_tag="VQT46_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2370416.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            32225..33025
                     /locus_tag="VQT46_000319"
     CDS             32225..33025
                     /locus_tag="VQT46_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET2370417.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRIYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            33035..34021
                     /locus_tag="VQT46_000320"
     CDS             33035..34021
                     /locus_tag="VQT46_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2370418.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
     gene            34157..34237
                     /locus_tag="VQT46_000321"
                     /pseudo
     CDS             34157..34237
                     /locus_tag="VQT46_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(34357..35298)
                     /locus_tag="VQT46_000322"
     CDS             complement(34357..35298)
                     /locus_tag="VQT46_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2370419.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(35276..37039)
                     /gene="aspS"
                     /locus_tag="VQT46_000323"
     CDS             complement(35276..37039)
                     /gene="aspS"
                     /locus_tag="VQT46_000323"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET2370420.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGTLRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
     gene            complement(37275..37355)
                     /locus_tag="VQT46_000324"
                     /pseudo
     CDS             complement(37275..37355)
                     /locus_tag="VQT46_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(37346..38635)
                     /locus_tag="VQT46_000325"
     CDS             complement(37346..38635)
                     /locus_tag="VQT46_000325"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET2370421.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(38713..39960)
                     /locus_tag="VQT46_000326"
     CDS             complement(38713..39960)
                     /locus_tag="VQT46_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET2370422.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGVSIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVSVIISSLTGNDYFGKQSLPRLMMWETVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(40151..41001)
                     /gene="rgg"
                     /locus_tag="VQT46_000327"
                     /pseudo
     CDS             complement(40151..41001)
                     /gene="rgg"
                     /locus_tag="VQT46_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398326.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes.; frameshifted;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
     gene            41125..41466
                     /locus_tag="VQT46_000328"
     CDS             41125..41466
                     /locus_tag="VQT46_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2370423.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            41524..41604
                     /locus_tag="VQT46_000329"
                     /pseudo
     CDS             41524..41604
                     /locus_tag="VQT46_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(41810..43513)
                     /gene="ilvD"
                     /locus_tag="VQT46_000330"
     CDS             complement(41810..43513)
                     /gene="ilvD"
                     /locus_tag="VQT46_000330"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET2370424.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(43746..44678)
                     /locus_tag="VQT46_000331"
     CDS             complement(43746..44678)
                     /locus_tag="VQT46_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET2370425.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATNNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(44675..45532)
                     /locus_tag="VQT46_000332"
     CDS             complement(44675..45532)
                     /locus_tag="VQT46_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2370426.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(45536..46882)
                     /locus_tag="VQT46_000333"
     CDS             complement(45536..46882)
                     /locus_tag="VQT46_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2370427.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMVIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSATEE"
     gene            complement(46895..47179)
                     /locus_tag="VQT46_000334"
     CDS             complement(46895..47179)
                     /locus_tag="VQT46_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2370428.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(47183..49213)
                     /locus_tag="VQT46_000335"
     CDS             complement(47183..49213)
                     /locus_tag="VQT46_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2370429.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NSHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLIDQVVKDYYEKLQLVPIVNQLKVYLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKWYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            49405..50412
                     /locus_tag="VQT46_000336"
     CDS             49405..50412
                     /locus_tag="VQT46_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2370430.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            50415..50615
                     /locus_tag="VQT46_000337"
     CDS             50415..50615
                     /locus_tag="VQT46_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2370431.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            50767..50949
                     /gene="rpmF"
                     /locus_tag="VQT46_000338"
     CDS             50767..50949
                     /gene="rpmF"
                     /locus_tag="VQT46_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET2370432.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKITKAASAE"
     gene            50965..51114
                     /gene="rpmG"
                     /locus_tag="VQT46_000339"
     CDS             50965..51114
                     /gene="rpmG"
                     /locus_tag="VQT46_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2370433.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(51606..>51752)
                     /locus_tag="VQT46_000340"
     CDS             complement(51606..>51752)
                     /locus_tag="VQT46_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET2370434.1"
                     /translation="YLNESGSMATGWVTVSGKWYYTYNSGDLLVNTTTPDGYRVNANG
                     EWVG"
BASE COUNT        15897 a        11100 c         9568 g        15187 t
ORIGIN      
        1 ccagaataat tcgctaattc tttttttagg gcgattgatt tgtacttccg tcgcatcaat
       61 cattatcgtg tcctcagagc tgagaggagt tcttgaaatc gtaacaccac ctttgaacaa
      121 gagttacttc aacccattgg ctccgacgga taaagaagac ttgataagaa ctctagagtt
      181 agctccccat gttgaaggtg gctattttag acaaacaaaa aaagcttcag acactataaa
      241 ccttgctggt aagggaaggg cgctttatac cagtatttat ttcttattag aagaaacgaa
      301 tccttcacat tttcaccgat tgacagcaga tgaaatctgg tattttcatg caggatcccc
      361 acttactgtt cacatgatta cagcagatgg tcactacgaa gcagtcactt taggcctgga
      421 catatccaaa gggcaacaac ttcactactg tgttcctaag ggcactattt ggggatcaac
      481 agttgataag gattatgctc tggtttcttg tcttgttgct cctggttttg aatttgagga
      541 ttttgaatta tttgaaaggg tagatctact ggcgacctat ccagagcaca aggagatgat
      601 tgagcgtttg accagatact agtcttgata agcaaattta atctgattta gcaatgttag
      661 gatttctgat aattgtgtta taatgttacc aataggagat aatagatgac aaaacaagtc
      721 ttattagtgg atgatgaaga acacattctg aaattgcttg actaccattt aagtaaggaa
      781 ggcttttcta ctcaattggt aacaaatgga cggaaggcct tagctttggc agaaacagaa
      841 ccctttgatt ttatcttgct tgatatcatg ttaccacaat tagatggcat ggaagtttgt
      901 aagcggctga gagccaaagg cgtcaaaact ccaattatga tggtttctgc gaaaagtgat
      961 gaatttgata aggttttggc cttggaatta ggggctgatg actacctgac caagcctttt
     1021 agccctagag aattgctggc gcgtgtcaag gctgtcctca ggcgaactaa aggagaacaa
     1081 gaaggagatg attcagataa tatcgctgac gattcttggc tatttgggac cttgaaagta
     1141 taccctgagc gtcatgaagt ctacaaggcg aataagttac tgagtttgac cccaaaagaa
     1201 tttgaactct tgctctatct tatgaaacat cccaacatga cactgactag agagcgtctt
     1261 ttggaacgta tctgggggta tgactttggg caggaaacac gtttggtgga cgttcatatt
     1321 ggtaagttga gggaaaaaat tgaagacaat cctaaagccc ctcaatttat tcgaaccatt
     1381 cggggttatg gttataagtt caaggagtta tagatgaaac gctaccttca attttggcta
     1441 gtcaatctaa gtgttagcct cattctgatt gcagggatgg cattaacttg gatcagtaaa
     1501 ggcatcggtc tctttcttct agccctttct ttgggacaag gtggctactg gctcttttgc
     1561 ctttggaaat gggaagttgc ttttgagacc ttgcaccaac ctctcttgac cagtagtgaa
     1621 tactttttag aaaaagggca agaagactta aagtctttgg ctcagtatgt gtctgcccta
     1681 aaaaccaaag tctcccaaca ggatcagcaa tacaaggacc tagccgaaac aatggaggtt
     1741 cttctgtcgc acctaaccat ggggacgttt ttagtttccg ctcaaggtca gatgttatta
     1801 tccagtcgct ctctgcctca ttattttccc gatgtggacg gcgacataag ttcacttgat
     1861 gacctcaaac ggatggatat tcgaaattta gttcaccaag cctttgatca aaaaacaagg
     1921 ttaaaacaag aagtaagtgg gtttcatgag ggtgacttga ttttagaagt gacagcagtt
     1981 cccgttttta gccccaccca atctgtggaa gctgtgctcg tcttgctata tgatttaaca
     2041 acgattagaa cttatgaaaa gttaaattta gcctttgtct caaatgcctc ccatgaattg
     2101 aggacaccag ttacttcgat taagggcttt gctgaaacca ttaaggggat gtcagctgaa
     2161 gaagaagcgc tcaaggatga ctttctagac attatttaca aagaaagctt gcgtcttgag
     2221 catattgttg agcatcttct taccttatct aaggctcaac aaatgcctat acaatggacg
     2281 accctttctt tggcagaatt tgtacaggat ttgactcaaa gcttgcaacc tcagctcaag
     2341 aagaaggatt tacagctaaa ggtgcaggtg ccagatgatg tcaccctcgt atcagatagt
     2401 caattacttt cccaaatctt actcaatctt ttatccaatg ccatccgtta cactgaacaa
     2461 gggggaaaaa ttgaggtcaa gacccaaaag gtgaacgaag gcattaagat ttctgtatca
     2521 gatacaggga ttggtattag tcaattagag caggatcgta tttttgaacg tttttaccga
     2581 gttaataaag gtcgaagcag acaaactggt ggcactggtc ttggccttgc cattgtcaaa
     2641 gaactcagtc aattattagg tggccaagtc acggtgacga gtcagcttgg cagaggcagt
     2701 tgcttcacga tttttcttcc taaccaatct ttcgcacagg actaataatt tttaaagcta
     2761 tttttaggag cagccatttt tcaaaagtgg ctttttttga ttctttacac aatctttaca
     2821 tgaatcaggg ataaaccttt acaaagactt gttagactat aaatgtagta agcctacaca
     2881 agaaaaatac atagagataa aggtgattat tatgaaattc aaaaaaatgc ttactcttgc
     2941 agccattggc ttatcaggat ttgggcttgt tgcctgtggc aatcagtcag ctgcttccaa
     3001 acagtcagct tcaggaacga ttgaggtgat ttcacgagaa aatggctctg gaacacgggg
     3061 tgccttcaca gaaatcacag ggattctcaa aaaagacggt gataaaaaaa ttgacaacac
     3121 tgccaaaaca gctgtgattc aaaatagtac agaaggtgtt ctctcagcag ttcaagggaa
     3181 tgctaatgct atcggctaca tctccttggg atctttaacg aaatctgtca aggctttaga
     3241 gattgatggt gtcaaggcta gtcgagacac agttttagat ggtgaatacc ctcttcaacg
     3301 tcccttcaac attgtttggt cttctaatct ttccaagcta ggtcaagatt ttatcagctt
     3361 tatccactcc aaacaaggtc aacaagtggt cacagataat aaatttattg aagctaaaac
     3421 cgaaaccaca gaatatacaa gccaacactt atcaggcaag ttgtctgttg taggttccac
     3481 ttcagtatct tctttaatgg aaaaattagc agaagcttat aaaaaagaaa atccagaagt
     3541 tacgattgat attacctcta atgggtcttc agcaggtatt accgctgtta aggagaaaac
     3601 cgctgatatt ggtatggttt ctagggaatt aactcctgaa gaaggtaaga gtctcaccca
     3661 tgatgctatt gctttagacg gtattgctgt tgtggtcaat aatgacaata aggcaagcca
     3721 agtcagtatg gctgaacttg cagacgtttt tagtggcaaa ttaaccacct gggacaagat
     3781 taaataaaat gtttgctcca taaatctcta aagagatgca gacgtttcat cgtacaataa
     3841 gataaagaag gcaagtaggg aggtgtcgta tctcccttac tttcttcact agaaaggaca
     3901 agatgtgaca aaacaagcct tcaaagaagc agtttttagg gcaatttttt tcatgagtgc
     3961 aacagtagct gttgtagcta ttttgctaat ctgtttcttt atttttagta atggcttacc
     4021 tttcatggct aactacggct ttgcccgttt tttattaggc agtgattggt cgccaacgaa
     4081 cattccggca agctatggta ttttaccaat gatcgttggt tccttattaa ttaccttagg
     4141 agcgattgtg attggggtgc caacaggcat cttgacatcg gtgtttatgg tttattattg
     4201 tccaaagccc gtctatggct tcttaaaatc agctatcaac ttgatggcgg ccattccatc
     4261 tattgtttat ggttttttcg gcctacaatt attggtgcct tggattagaa cctttttagg
     4321 aaatggcatg agtgtcctaa ccgcttcgtt actattagga ataatgattt tgccaaccat
     4381 tatcagtttg tcagaatctg ctatccgaac agttcccaaa acgtattatt ctggtagctt
     4441 ggctctagga gctagtcatg aacggagtat ttttagtgtc atcttgccag ctgcgagatc
     4501 tggtatttta tcagcagtta ttttaggaat cggtcgcgca gtaggtgaaa ccatggcagt
     4561 tattttggtg gcaggcaacc agccgattat tccaagtgga ctcttttcag gaaccagaac
     4621 cttaacaacc aatattgttc tggaaatggc ttacgcatca ggtcagcata gggaagccct
     4681 tattgcaacc tcagcagttc tctttttcct tattctcttg attaatgcct actttgccta
     4741 cttgaaagga aaatcatctt atgagtaaat acctgctaaa acttctcgtt tattgttttt
     4801 cagctttaac ctttggctct ctctttttaa tcattggttt tatcctcatc aaaggcttac
     4861 ctcatctaag tctatccctc ttttcttgga cttatacttc tgagaacatt tcccttatgc
     4921 cagcgattat ttccaccgtt attctggtct ttggtgctct tcttttagcc ttgcccatag
     4981 ggatttttgc tggtttttat cttgtggaat atacaaaaaa agattccctt tgtgttaaaa
     5041 tcatgcgatt ggcctcagat accttgtctg ggattccttc cattgttttt ggtctgtttg
     5101 gcatgctctt ctttgtagtc ttcttaggtt ttcaatactc tctgttatca ggaatcttaa
     5161 cctcagtcat catggtgttg ccagtcatta ttcgctcaac agaagaagcc cttttatctg
     5221 ttagtgatag catgcgtcaa gcaagttatg gacttggggc aggtaagtta cggactgttt
     5281 ttagaattgt tctaccagtt gccatgccag gtattttagc tggagtgata ctagctattg
     5341 gccgtatcgt tggtgagaca gctgccctca tgtatacatt aggtacctct accaatacgc
     5401 caagtagtct catgtcttca ggtcgttctc tagccctgca tatgtatatg ctgtcaagtg
     5461 aggggctaca tgtcaatgaa gcctatgcta ccggtgtgat tttgattatt actgttttaa
     5521 tgataaatac tctatcaagc ttattatctc gaaaacttgt gaaaggagct tcctagtatg
     5581 ggaacatttt cagtcagaca cctagactta ttttacgggg attttcaagc cttaaaaaat
     5641 atttcgattc aattaccaga aagacagatt actgccttga taggcccatc tggttgtggc
     5701 aaatcaactt ttctaaaaac ccttaaccgg atgaacgatt tggttccttc ttgccatatt
     5761 gaaggccaag tcctcttaga tgagcaagat atttatagta gcaaattcaa ccttaatcag
     5821 ctacgcaagc gtgtagggat ggtttttcaa cagcctaatc cctttgccat gtctatctat
     5881 gataacgtgg cttatggtcc aaggacacat ggtattcgag acaaaaaaca attagatgcc
     5941 ttagtggaga aatctttaaa aggggcagcc atttgggaag aagtcaaaga tgatcttaaa
     6001 aagagtgcca tgtccttatc tggcggtcag cagcaacgcc tttgcattgc gcgagcttta
     6061 gcagtagaac ctgatgttct gttaatggat gagccgactt cagccttaga ccctatctcc
     6121 actttaaaaa ttgaagacct cattcagcaa ctaaaaaagg attatacgat tatcattgtt
     6181 acccataaca tgcaacaagc ttcacgtatt tcagataaaa ctgctttttt cttaacagga
     6241 gaaatttgcg aatttggaga taccgttgac gtgtttacca atccaaaaga tcagcgcaca
     6301 gaagactata tttcaggacg gttcggataa ggaaggaaaa acctatgaga aatcaatttg
     6361 acttagaatt gcatgaatta gaacaatcct ttttaggact agggcaactt gtccttgaaa
     6421 cagcttcaaa agccttactg gccttagcct ccaaagacaa ggagatggca gagctaatta
     6481 tcaataagga tcatgctatc aaccaaggtc aaagcgctat cgaattgacc tgtgcccgtt
     6541 tgttggcctt gcaacagcca caagtgtctg accttcgatt tgtgattagc atcatgtctt
     6601 cttgttcaga ccttgaacgt atgggagacc atatggcagg cattgccaaa gctgttttgc
     6661 aactaaaaga aaatcaacta gcccctgacg aagaacagtt acaccaaatg ggtaaattat
     6721 ccctcagcat gctagccgat ttattggttg cctttccttt gcaccaagcc tcaaaagcta
     6781 ttagtattgc tcaaaaagat gaacagattg accaatatta ttatgcctta tcaaaggaaa
     6841 tcattggact tatgaaagac caagaaacct caattcccaa tggaactcaa tacctttata
     6901 tcataggaca tctggaacgc ttcgctgatt acattgctaa catttgtgaa cgcctagtct
     6961 acctagaaac aggagaacta gtggatttga attaattcaa ctaatcctta aaagagaaga
     7021 gtacgattaa gtgctctttt ttatggttgt aaaaaagttc atttgaacaa tttaagcagt
     7081 gtagatagtg aggagctgtt tcaattctat cgtgaacgag ggaatgctga aaactttatc
     7141 aaagaaagga aagcaggatt ctttggggat aagacagata gttcgaccat gattaagaat
     7201 gaagtacgta tgatgatggg ctgtctggct tataatctct acctcttttt aaagcagcta
     7261 gctggtgatg aagtaaagtc cttgactatc aagcgttttc gacgtctctt ccttcatatt
     7321 gccggaaaat atgtctctac tgctagacga catattctca aattctcaag tctatacgcc
     7381 tattcaaaac agtttcaagc cttatttgat acaatctgcc agataaatct gatactccct
     7441 gttccatata gagctagagg gcaggggaaa acatgcctaa cagaataagt caccttattt
     7501 taaaaatcga gcatcaaacc aagggaggag tctgcccttt tttaggaaaa aatcaagaca
     7561 aatctcctca atcatgtctc gaacatcaga aattaagcaa aatcaccaga aggacagtat
     7621 ttcaactagc ttttctggta atttttgaac tgtgtagttc gctagtgcta gatatgaata
     7681 atttgggatg ataaatcttt cttcctcagg tagcctatca taatactctt caaaaatctt
     7741 agcaaaaaca ctctctttct tttgggcgat agtttcatct tcgtatgtag gagtcctcat
     7801 caagaaatac ttcaattcta ggtattcctt atccaactct atataacttg gcatcaactt
     7861 gtaatcttca ccccccccaa acgttcagcg atatatttta actttgttag tgttggtctg
     7921 gattctccat tttcaattct aattaattga cggatactta attcagactc atcaccacaa
     7981 aattctgaac gactgatttt tttagccaaa cgtaatcttt taattttttc gccaaactct
     8041 cgcaacctac aagaacctcc tgagttgttt acctctattt atagcatata ctgaatcaaa
     8101 ctatctatca gatttcttct cactttaact aaagactaag agtttatccc ttcatctcgg
     8161 tctttgtgta tttttccacc ataccccagt aatgcaagtg caaaatcctc tagaatatga
     8221 tagaataatg gaaagaactc tatcaaggag gaaatcatgg aaaaacaaac cgtcgccgtc
     8281 ttggggcctg gttcttgggg aactgccctt tcacaagtct taaatgacaa tggacacgag
     8341 gtacgtattt ggggaaatct tcccgagcaa atcaatgaaa ttaataccta tcatactaac
     8401 aagcactact ttaaagatgt cgttctagat gaaaatatca ttgcctacac cgacttagca
     8461 gaaacattga aagatgtgga tgcgattttg tttgttgtcc caacaaaagt gacacgactt
     8521 gttgcccaac aagttgcaca aaccttggac cataaggcta tcatcatgca cgcttcaaag
     8581 ggattagaac ctgatagcca taaacgatta tcaactatcc ttgaagaaga aattcctgaa
     8641 cagctccgca gtgatattgt cgttgtttca gggcctagtc atgcggaaga aaccattgtg
     8701 cgtgacctaa ctttaatcac tgctgcttct aaagatttac aaacagctca atacgttcag
     8761 gagctattta gtaatcacta cttccgactt tataccaata cggatgttat cggggttgaa
     8821 actgctggtg ctcttaaaaa tattattgct gtcggtgctg gagctttaca tggtcttgga
     8881 tttggtgata atgctaaggc agccatcatc gctcgaggtt tagcagaaat cacccgccta
     8941 ggggtagcac tcggggccag tccattgacc tatagcggct tatctggtgt gggagatttg
     9001 atcgtaacgg gaacttccat ccactctcgt aactggagag ctggagatgc tctcggacga
     9061 ggagaatccc tagctgatat agaagctaat atgggcatgg taatcgaagg aatttcaacg
     9121 actcgagcag cctatgaact agcccaagaa cttggagtct atatgcccat tacacaggct
     9181 atttaccaag ttatttatca cggaaccaat atcaaagatg ccatttatga catcatgaac
     9241 aatgaattta aagcagaaaa tgagtggtct taaccctcta tagaaaggat ttttatgaca
     9301 tcaaaagtta gaaaggcagt catccctgct gctggactag gaactcgatt tttaccagca
     9361 accaaggccc ttgccaaaga aatgttgcca atcgtagaca aaccaactat ccagtttatc
     9421 gtggaagagg ctctcaaatc aggtattgaa gatattctag ttgtcactgg taaatcaaaa
     9481 cgttctattg aggaccactt tgattcaaac ttcgaattgg aatataacct caaagaaaaa
     9541 gggaaaacag atcttttgaa gctagttgat aaaacaactg acatgcgtct gcattttatc
     9601 cgccaaactc atccacgcgg tctcggagat gctgttttgc aagctaaggc tttcgtcgga
     9661 aatgaacctt ttgtcgttat gcttggtgat gacttgatgg atatcacaga cgaaaaggct
     9721 gttccactta ccaaacaact catggatgac tacgagcgta cccacgcgtc tactatcgct
     9781 gtcatgccag tccctcatga cgaagtatct gcttacgggg ttattgctcc gcaaggcgaa
     9841 ggaaaagatg gtctttacag tgttgaaacc tttgttgaaa aaccagctcc agaggacgct
     9901 cctagcgacc ttgctattat cggacgctac ctcctcacgc ctgaaatttt ccaaatcctc
     9961 gaaaaccaag ctccaggtgc aggaaatgaa attcagctga cagatgcaat cgacaccctc
    10021 aataaaacac aacgtgtatt tgctcgtgag ttcaatgggg ctcgttacga tgtcggagac
    10081 aagtttggct tcatgaaaac atccatcgac tacgccctca aacacccaca agtcaaagat
    10141 gatttgaaga attacctcat ccaacttgga aaagaattga ctgagaagga ataaaataaa
    10201 ataaaaagat aaggttcaaa aaatgcctta tcttttttca ttacacaaat tttctttcaa
    10261 cttcgtcaca ttcccattcc cttgtagaaa agcaaaatgg cgagtcctac gaacaagact
    10321 accgctccta atctctggct ggtattatac atccgttttt ctcctctaac tggaaagata
    10381 actgctagaa atgcgccacc aactgcacca ccgatatggc ctgctaggct gattcctgga
    10441 atcagaacac ttccaataat gttaactaca aaaagtgtca gataggattg ccctagctgt
    10501 tgaatataag gattgcgagt tgcatagcga agaacaataa tcgcggcaaa tagcccataa
    10561 agagaggtag aggcgcctgc tgctaaggat ttaggactaa atacaaaaac aaagagattg
    10621 cccatcattc ctgataaaag atagagaaag aaaaactgct tagaaccgaa aatctcctct
    10681 acctgccttc caagataata aagtgaaagc atattaacaa tgaaatgttc ccacccaata
    10741 tgaacaaaaa tggcagacaa gagacgccaa acctgctcgg gaaagaggcg aatagctggc
    10801 ccatacatgg ctccaaatcg aaataatgta tctgccctgt caaagtttcc gcctgcagtg
    10861 accaacatta gtaaaaatac caaggccgtc actaagagga agaaactcgt cacagggtaa
    10921 cgtctatcaa agatttcctt catcaattaa tacctcctga acaggaatat catggttttc
    10981 aggtataaag tcctgaattt gacaaggata tatcgtactc aaagcacgac cagaaaaatg
    11041 ttccagatag cggtcataat aacctccacc atatccaatc cgatatccat ccgtcgtaaa
    11101 agccaggcca ggaacatgaa tcaaatcaat ctgagatgca tccactactt ccaaatctcc
    11161 ctgtggctcc agtaaggcaa aggaagtttt taccaactgt tgcggatcat agaccacaaa
    11221 atccatgcgc cccttgggat aggtcttagg tgtcaaaacc ttcttgccgt ccttcagcgc
    11281 ctgctcaatc agttcccgcg tttgaaactc atgagaaaaa gagaggtagg ttgcgatgac
    11341 cttggcttct tgataaaagg ggtgttgtaa aattcgctcg gttaaagctt ggtctatagc
    11401 ctgtttttgc tcttgagata tagccttcat ttcatgcaag acttgcttgc gtaattccga
    11461 tttcatagac aagccctcta ttctgctgcc ttctttttca ggaaactaga caccgcagcc
    11521 accccaatag ctaagacttc ttccttagga ctcatttgag ggtgatgaag agcgtaggga
    11581 ctatcgatac ctagccaaaa catcacgcca tcaacctttg aaaggagata accaaagtcc
    11641 tcgcctgtca tagcaggttc gatatcaatc aactcgattc cgtctttctc gtcaaagaag
    11701 tccatcagtt cacgcgccaa ggctggattg ttctcaacag gtaggtatcc accttgtttg
    11761 agttccactt cgacttccat atcaaaggca gctgcaaccc cttctgcaac tgtttttacc
    11821 ctcttttgca ccaagagact catgtcctgt gtcaaggcac gaatagttcc atgtaaaaaa
    11881 gctgtgtctg tgatgacatt gttggtggtt ccagcttgaa aaacgccgaa ggtcaccact
    11941 gctccctcga ttgggttgac attgcggcta acaactgact gcacttgggt cacaaagtaa
    12001 ctagccgcca ccaaggcgtc attggcttca tgaggaaaag ctgcgtggcc acctttacct
    12061 ttgaaacgga tcttcacctc gcaagttcct gcaaagagtg tatgagtatt agtcgcaatc
    12121 tggccgactt tcaaatctgg acgaacatgg agaccataga attggtttgg caaccaatct
    12181 ccaaaagcac cgtcctcata catgagcata ccaccagctt cattttcttc agcaggctga
    12241 aatagaaaga gcagattatt cttgggttgc tcctcaaggg cgcgctcaag acagcctaag
    12301 gcaatggtca tatgaaaatc atgaccacag gcatgcatgc gaccttggtg ttgagaagta
    12361 aaaggtagac ctgtttgttc gacgataggc aggccatcaa tatctgtccg ccaaccaatg
    12421 gttcgctccg gctgacttcc ctgcaggtag accaaaatcc ctgtccgcca agtacgaatt
    12481 tgaacaaaat ccttgcccgt agtcaatttc tcaatcacat ccagcaaata agcctgagtc
    12541 ttgaactcct ccaagccaat ctctggaatc tggtgtaaag ctcgtctagt ctgaatcaaa
    12601 tctaacatct atctgtcctc cgatatagca gaaagaggct ggaaaaaggg ttccgcctct
    12661 tttttacttt tacaattaca aggtacgaag cgcatcctct agcgctgttt tttgttgagt
    12721 ttgggcatca atttctttga taatacgagc tggaacacct gctactacca cgttttctgg
    12781 gacatcttgg gtaacgatag ctcctgcagc gacaactgaa ccactaccga tttggactcc
    12841 ttcgataacc actgcattag ccccgataag aacattgtct ccgacacaga ctggttcagc
    12901 actagctggc tcaatcacac ctgccaaaac tgcacctgca ccaacgtggc tattttttcc
    12961 aacgatagca cggccaccaa ggatggcacc catgtcaatc atggttccag caccgatttc
    13021 agcaccgata ttgataacag ctcccatcat gataacagca ttgtcaccaa tttccacctg
    13081 gtcacggata atagcacctg gctcgatacg agcgttgata gcacgcttat ctagcaaagg
    13141 aactgcagaa ttacgagcat cttgctcgac aacataatct tgattttcta ccaaaccttc
    13201 aagaagcgga gccacgtcct tccagtctcc gaataggaca tttcctagtt tgacaacaga
    13261 gctaggcaca gcagttgcga gttgcccctc aaaggttact ttgacactgg ttttcttttc
    13321 agcattggcg ataaattgga taatttcttg agcgttcatt tttgtagcag tcataggtgc
    13381 ctcctggttc gttataatga tacctattct accaaaaaag gcctcaaatt tgaaaccttt
    13441 ttgtctgttt ttaggtatga ttttttaggg atgtgagata aaacgtgctg tcggtaaaag
    13501 caagccccta ccgatacaac ctaaaaatac tcttcacaac tatctccccg tgttttattg
    13561 actattctag tatagcacac ttttagaatt aagaaaagac tttttatcta ctttctttcg
    13621 cttcttctat agacaaaaat atcatgggta aaataatcaa ggctatagct agaaggaggg
    13681 accaatccac tactaatcct aagaacaaaa cactcaagag agcagaagag agaggttcac
    13741 tggcactgat aacggaaacc accaaaggag aaaccaagga cacagccttc atggaaatga
    13801 aaaaagcaaa agccgttcca aagaaagcga taatgaggca aatcaagata ctccaaatat
    13861 caagagtaaa ggaaagctga taaaccggcg agaggacatt gctaaacaaa cctgccaaaa
    13921 tcatccccca cccaaccgta ggaacaaaac cataacgctt agcaaaaggt tggggcaaga
    13981 taacattaaa cataacaccc atggcactca gcaaacctgt tataagagct agcggcgtca
    14041 tggataactg agagagatct ccctttgtcg ccatcaagca aacacccagc atggcaacca
    14101 aaacatagaa aacagcgctt tttgacgctc gtttttgata aaccaagcga ttgtaaaaga
    14161 ggataaagac agggctaata aactgtaaaa tagttgctgt cgtagcattt gagtattcta
    14221 aacagagata gaaaaaatac tgaactgaaa aaatccccaa aatagcatag gctaaaaagg
    14281 gcaggtaatt tttcttgtct cgccaaatat ctagcacttg cgattttaat tgtattgcag
    14341 accaaatgag tacaagactc cctgccagtg tcaaacgcat agaggtaatc cagcccgaag
    14401 acacctgata atgagtaaag aagtactctc ctaaaattcc acagattccc catattaagc
    14461 cggataggag cgaataaatt tttccgttaa caatcttttt ctgatactga ttcataccct
    14521 tattgtaaca cgaaaggaaa aaagtggcaa tccattgatt ggccacttca tttagagaat
    14581 tatcgtctcg cccttgaaga agaaggtcgt gtagtacttg agttactgct atcgctagaa
    14641 ctactacttg aactgctgga gctggatgga gttggtagac tccccacaat actagaccaa
    14701 gcattctgat aatccgcatc acttccgcca atagcaaagc gataacttgt cgctggcgct
    14761 cctgacttat tagcccaata gctggtaaca gtcgaacctg tgacctctac ctcttttcct
    14821 tcaacagaaa ccttccctgg tttttgacct gttgatttca agacttccga tttcactaca
    14881 ctaggatcta aagcaaagcg ctcgttcccc caaatgcttg gggaagcttg ctgaatcgca
    14941 tttaccagat gagccatgta attagagtta ttagaataac ctgctctacg tgacaatgaa
    15001 tgattatcat catgcccaat ccagccacct agggttaatc taggtgtcga aagcatgagc
    15061 cacatatttt cgtcttggtt ggttgtacca gtcttcccaa tccaatctgc attagccaga
    15121 gtaggattta aagaagtcag gttagacttg aaggttgttg tcacacgaga ggatagaact
    15181 tctcgtagca atccctgcat aatcgtcgca gtagcttttg aatagacttg aaccggttta
    15241 tcctgatact catacaccac tctaccatct gctgcttcaa tctttgaaat cacatgcttc
    15301 tgatgataaa ctccattatt agctaaggtc tgatagccat tggtatgctg ggcaactgtg
    15361 acttcaatac caccacccat tggcaagctc tcaataccgt actcaggaat ctcgtaaccc
    15421 atcttttcca tataaccctt gacatcaaca cccttttcac ggagcatacg ataggtccag
    15481 taagcaggga tattccatga atagttcaga gcttctccca aggtcatcat tcctgttccc
    15541 ttgctattag catacataat cggattgcca ttagcaaagt ttgttggata gttagataga
    15601 atcgtttcac ttcccatcaa gccctggtca atagcaatac cgtaggccag caagggcttg
    15661 gtagtagaag ctggcgaacg ttttgtatca aaggcatgat tattttgatt ttcttgataa
    15721 ttacgaccac ctacaaagcc tagaatagca cctgtttggt tatccatcaa gacattccct
    15781 acttctacac gacctgttcc atcgtctaaa agatagccat aatcagcaac cgcactttgc
    15841 atggcagaat gaattttctg atctatggta gtagtaatct tataaccacc attttcaatt
    15901 tccttggctg ccaaatctcg ataaaacttc tgagttgcct catttttcaa ctccttagcg
    15961 gagacattgt ctctctgagc tagatagtca tacatacgtt cttgagcttc tgccaaagtt
    16021 gtaaagtata aatagtctcg tgaaattcct gtaaccgtgc ccgatggtaa aaagtcctgt
    16081 ttaaggtcat aatccttgta ctgagaatac tcgtctttgc ttaatgcacc tgtacgatac
    16141 atactgtaaa gaactgcctt agcccgtctt aagccaattt ctaggtcttc atcactcttc
    16201 aactccccag tattttcata aggagagtaa gtaatgggac tctgtggaag tcctgctaaa
    16261 aatgctgctt gaggaacagt caactgactg gcatctacac cgaaaattcc ctcagctgct
    16321 tgccgagccc ctgcaatatt ctgtccctta ttatttcggc caaagggagc cacattgaga
    16381 taggtcgtta aaatctcatc tttattcatg gcgcgttcca aggcaagagc atccacaatc
    16441 tctgccgcct tacgagccaa ggtcggcgca tccccaacaa cctgctgttt aattagttgc
    16501 tgggtcaagg ttgaaccccc actagaggaa cccaaaccta caaatttccc caaggtcgca
    16561 cgaatcaccg ccttgggtac tacaccctta tgttctttaa agtgttcatc ttctgtcgca
    16621 atgatagcct tcttcagatt ttccgaaatt tgctcagatg agatagaagt gcgcaacaaa
    16681 tcactctcta tggaagcaat caccgtcccg tccgaatagg taatctctga aatagaagag
    16741 atgtccttga cctgattcac caattcttct gtctgaggca cccgaacctt gtcaaataag
    16801 gccactccgt accccaaagc aatcccaact cccaacattc ctcctagaaa accgagtaca
    16861 aagagtaagt taaataaggc ttttatactc agtaaaatag ctgggaaaat ggctgactta
    16921 tctaaggttt tagatttttt ggtacttgaa cctttcttgc caggtctagc tgatttttta
    16981 tttttttgtt tttgctggaa aaattccagc atttttcgtt ttaattcatt taattgattt
    17041 tgcatggatt tcctcacttt atctattata ccacaaaagg gaaattttca ataaaatagc
    17101 cactttcttc cctattctgc taggctattg cccaagtttg tgatacaata ggtagaaaca
    17161 ataattttaa aaaggagaaa agacacatgc acatttttga tgagctaaaa gagcgtggtt
    17221 tgatatttca aacgactgat gaagaagctt tgcgtaaagc cctagaagaa ggtcaagttt
    17281 cttattatac tggctacgat ccaactgctg acagccttca cctaggccac cttgtcgcaa
    17341 tcttgacaag tcgtcgcttg caactagcag gtcacaaacc ttatgcgctc gttggcggtg
    17401 ctacaggtct catcggagat ccgtccttca aagatgctga acgtagtctc caaacaaaag
    17461 acacagtaga tggctgggtc aagtctatcc aaggacaact ttctcgtttt cttgactttg
    17521 aaaatggcga aaacaaggct gtcatggtca acaactacga ctggtttggc agcatcagct
    17581 tcattgactt cctccgtgac attggaaagt acttcacggt caactacatg atgagtaagg
    17641 aatctgttaa aaaacggatc gaaacaggaa tttcttacac tgagttcgct taccaaatca
    17701 tgcaagggta cgacttcttc gtccttaacc aagaccataa tgtcactctt caaatcggtg
    17761 gttctgacca gtggggaaat atgacagctg gtaccgaatt gcttcgtcgt aaggcggaca
    17821 agactggtca cgttatcact gttccactaa tcacagatgc aactggtaaa aaatttggta
    17881 aatcagaagg aaatgccgtc tggctcaatc ccgaaaagac ttctccatac gaaatgtacc
    17941 aattctggat gaacgtgatg gacgctgacg ctgttcgctt cttgaaaatc tttactttct
    18001 tgtcacttga tgagattgaa gatattcgta aacaatttga agcagcgcca cacgaacgct
    18061 tggctcaaaa agtcttggct cgtgaagttg ttacacttgt tcacggagaa gaagcctaca
    18121 aagaagcact taacatcact gagcaactct ttgcaggaaa catcaaaaac ctttctgtca
    18181 aagagctcaa acaaggactt cgtggtgtgc caaactacca agtacaggca gacgaaaaca
    18241 acaatatcgt ggaactgctc gtctcatctg gtatagttaa ctcaaaacgc caagcccgtg
    18301 aagacgtcca aaacggagcc atctacgtaa acggcgaccg catccaagac cttgactatg
    18361 tcttgagtga cgctgataag ttagaaaatg aactgactgt tatccgtcgt gggaagaaaa
    18421 aatactttgt attgacttac taaactattc aacatttatc tataaacaaa ggagttaacc
    18481 tcgagaaagg taactccttt ttgctgttaa taactctcat ctatctattt ttaatagaca
    18541 ggctacgcag gacaatgcgc aaggttgtta gattatgtaa gatagagaga tttgaaggac
    18601 tgaaccaatt aaataagcca aagccaatca aactactatt tacgacaacg gtatcctgaa
    18661 tatttttctt gatgagtgtt tgcaaagatg atgataacga atccaactct tggaagaaat
    18721 ccaaacgatt atctaacaat aagatatcac tcatctgctt agaaatatct gcactctcat
    18781 tcatcaccac accgatatct gatagagtta aagccgctga gtcattcaat ccatctccaa
    18841 ccatcaaaat agtgtgacct gctttctgca gtttctctac taactcaaat ttcccatcag
    18901 gtttcaagtc tgtatagacc tgatcaaagg gcaaatcttt gactaattcc tctgtcctaa
    18961 tcaaggtgtc tcctgttgcc agaatcaatt ttttcccctg tgccttaagt ttatccaagg
    19021 ctgtttttgc ttcttttctc aaaggagtat gaatgcagaa cattccaatc aattcatttt
    19081 gataagccaa gaataagaga ttgtagtgac tcttgtactc ttcaattaaa gcattttgtt
    19141 ctgaactgat atgaatctgc tcatcctgca tcaagacata attcccaata agaactggtt
    19201 ggccatctat atgagatttg atccccttgc ttgcgatata ttggagtttc ccatgcattt
    19261 cctcatgttc aattccctct atctcagctt gcttgacgat ggcattagca ataggatgat
    19321 aaatgtgttc ctcaagacag gcactgattc tgagaatatc ttcctcacta tagtctccaa
    19381 aaggtaacac cttttcaact ataggataac tagttgtgat tgttcctgtc ttatcaaaca
    19441 agaaagtatc aacttccaga tatttctcca gaacatctcc atccttaatc accatttcac
    19501 ggttcaaccc ttccttgata actgtcaaat aagctacagg agtagagatt ttcaaagcgc
    19561 aggagaaatc gaccaatagg aaagaaatag ccttagaaaa agaacctgtc aataggtaag
    19621 tcagcccagc ccccaagaaa ttatatttga cgactttatc cgccatcttg atgaaatagc
    19681 gttgtttcgt tttcttgttt tcttcagatt tcttcatcaa ctcaatcagc tgtaaaatac
    19741 ggctgttcat ctgattatct gttacacgaa tgcgtaactc tccagtttct aatactgtat
    19801 ttgcacaaac caaatcagac tctctttttt caactggaaa actctctcct gtcaaggaac
    19861 tttcgttgac catacctaaa cctgaaacta cttgtccatc aaacagaatt tcatttcctt
    19921 gagataagat caagacatct cctatttgaa catcggaact cttgatacta acaaccgtat
    19981 cgccctgtac taggaataca tcgctctctt ttgcaagaag actctgttct aaatctgttg
    20041 cagttttttt caaggaccac tgatctaaat gattccccaa atcaagcata aacatgatat
    20101 tgctagctgt cttggattgg ttcataaaca aggacaataa aatagccgaa cagtccaaga
    20161 cttccatcgt tagttcctta cgcgctagtg tttgataggc ttctctaata taacccaaag
    20221 cctgataaca agtccatata tagcgaatag gatacggcac aaaactacga aaaagtacac
    20281 gcttaaccgc tgcacctgaa acaatagaat aagcactctc ttctctacga atgggaagag
    20341 tcatcaactc agaaactttc cctttatcaa ttctttttaa aaaggcttct gcattatcta
    20401 atacagaaaa gccttctttt atgcgtagag taaagtgctg ttgatccatg taaaactgga
    20461 tagactcaat ccccttttca tctctcgcca aggaacgaag atagtcttga atatccaagg
    20521 taagtgaaaa agaagatgat agtcggatat gttggtatcc tctatgtagc actttaaaag
    20581 acatattatt cacctataag gctatctaat tgctcttctt ttttctcttg ctcgtacaaa
    20641 tatttggcat cttgcaagac atcgtctcca tgttgcttca caacagaaac agatgcatct
    20701 agctcgtctt tcaacttgta agccttagcc aaagctttag aataaccttt tttagcttcc
    20761 ttacttgcta agattttcaa accaagggta ccaaatgcga caccacccaa aaataatgaa
    20821 gattttttcg caacttttgc aacggttaat acttctttta acatacttat ttcctcctta
    20881 tcattattat atagcaattt agatataaaa gcaatttcat tctataaatt ggagaattag
    20941 ttttatttct actgaatcta cttattccta aagttgcttt catttgcctc ttttgataca
    21001 cttaaactat gaatacaaat ctcaagccca aacttcagcg ttttgcttct gcgactgcct
    21061 ttgcctgtcc tatctgtcaa gaaaatctga ctctgttaga gactaatttc aagtgctgca
    21121 accgtcattc ttttgacttg gcgaaatttg gctatgtcaa tctagcacct caaatcaagc
    21181 aatctgctaa ctatgacaag gaaaattttc aaaaccgtca acaaatccta gaagccggct
    21241 tttaccaagc tatcttagat gctgtatctg acttgcttgc aagctcaaaa actaccacaa
    21301 caattttgga tatcggttgt ggtgaaggat tctattctcg caaactacaa gaaagtcact
    21361 ctgaaaaaac tttctatgcc tttgacatct ccaaagattc agtccaaatc gctgctaaaa
    21421 gtgaacccaa ctgggcagtc aattggttcg ttggcgactt ggcacgactt cctataaaag
    21481 acgctaacat ggatattctg cttgatatct tctcacctgc caactatgga gaatttcgtc
    21541 gcgttttatc caaagacggt atcttgataa aggttatccc aactgaaaat cacctcaaag
    21601 aaatccgtca aagagtacag gaccagctga caaacaagga gtattctaac caagatatca
    21661 aggagcattt ccaggaacac tttaccatcc tatctagtca aactgcctct ctgactaaga
    21721 ctatcacagc agaacaactc caagccctac tcagtatgac tcctctcctc tttcacgttg
    21781 accagagcaa gattgactgg agccaactga cagagattac catcgaagca gagattttgg
    21841 ttgggaaagc attctaaact agacttccca aaggtataaa acttaccgaa aatcttcaat
    21901 attataaaaa cgcataagaa caggtacaca aaccttaatc ttatgcgttt tgttatagtt
    21961 tccatacaca ttaaggggaa atagttgaaa tcagttctct taataaccat tgaataccat
    22021 atactacatt taccccaaat atgatatagg ccgtataaat caagtatttc gatttttccc
    22081 gcctcaaaga atagatctta tacaaaataa ataaatttaa aataataaat aatagagaca
    22141 aaatcttcct ccaaaatcaa tcctaaaagt acacagtcaa gcatagctct aatctttatt
    22201 ttcgattcga tataacaaac ttatcaatga atagtaagtg atataaggcc agtaccagac
    22261 cccaaacgct accacgaaaa gagaattctt gatgattgag agtaaacaaa tcatggttac
    22321 caatatagag gcaggtcaaa ataacaaata aaatccaaaa taaatccgtc catttatatt
    22381 ttgaaaaata tttttttaac ataatagcat atttttttga ctataataac agcatatgat
    22441 aaaatgtaag cagatacaaa taaaaaggag aaaagctcat gaacaaatta atgaaattta
    22501 tttcggtttt tttgacgtca attgtgttaa ttgtatcagc gattccaagt gtttcagctg
    22561 tatacgcttc tgaacaagta tcacaaattg aaacaaatat ggaacttcaa cctgtcactt
    22621 ctctaacaga agaacaaatc aatacacttg caaacgaaat ccaatctttt catccagacg
    22681 tctcacaaca atggatcaaa gaagtaatta accgacaatt acaaggcgat tatacaatcc
    22741 cacctacata ctctccattt agagcagctt ggcaaggtat tacagttaat caaatgggtg
    22801 ctctattaga tactgcaata gctttagcat taggaggaac tactgcaggc cttgcaaatc
    22861 taattaaagt aaaaggaaaa catgcagcaa aaagtgctat tcgttcagca atttctagat
    22921 atctaggtag ttggtttgta aatgatgttg ctttagaatt tgctataaat ttattatcac
    22981 cggggactta tttagcacaa ttatgggata aaaatgatgc cattcctaac aacggaagga
    23041 ttaactttta atcatgagat atacaataaa attaattggg tataacgtat tttcgttgtt
    23101 tatattcttt atcttatcaa tgttgtttaa agtttccttt aggtggtgga tcagcattgc
    23161 aatgacgact tcgtcgtaca ttgtatataa ttacttaaag aaaaagagag aaaaggaatg
    23221 atcttatacc agatcattcc ttttctgctt tctgtaaatc cctcggagtg tgtttggcgc
    23281 tttgatacga agtgtcaaag ctgtataaac gttactattt ccaaaaaagt aacagaaaat
    23341 tcctgctttg taggactgct ttgggtgagt aatagacatg tcgactcacc ctatctcctg
    23401 atggcgaaaa gaatttagca atggtgcaag ttgttctgaa ctcgagaaaa aacatgccga
    23461 aatcgaagaa aagcgtgcag aacttgaagc gaagaagcaa gaaatgttga agcgcttgga
    23521 taaatagaat ttagaaaaca gaaaaaacta aaaagaatgt agggtttatt tccctacatt
    23581 cttaaaataa cttagtacat aaatgacaat gctgccactg ccgtcaatat tgcaaaaact
    23641 attttccaaa tttttttatt ttttccaaaa atcttatcag gtaacaagct tattacaaga
    23701 aaggtaataa acaacaccaa tttaagtgtg tatatcataa aaacaccttc tttcctacaa
    23761 ttatattata atactttatg taagcgaata caagaggtat gaggtaatca actacgaaaa
    23821 aatataaggc tgaggacagt aaaaaccagc atttaaagcc ttcactgtat ctaggatttc
    23881 cctattttta gacaagattg acccaaatct acatcattaa aaaagcgaat ttcaatcgaa
    23941 actcgctttt ttacaagatg tattagtata aatttgtatc ttatactcaa tgaaaatcaa
    24001 agagtaaact aggaagctaa ccgcaggttg ctcaaagcac cgctttgagg ttgcagataa
    24061 agctgacgtg gtttgaagag attttcgaag agtattagtt caagtgccag atgtcttcgt
    24121 tatactgagc gattgtacgg tcagatgaga agaatcctgc tttagaaatg ttaacgatga
    24181 ctttatccaa ccatgcgtca cggtcttcgt agtcagcaag catttgctct ttgactttga
    24241 tgtagtcttc caagtcaaga agagtcatga accagtcttt gttgatcaat tcattgtaaa
    24301 gacgttccaa gcgctctttg tttccagctg caagaactgc atcactaacg atgaagtcaa
    24361 ccaatggttt gatagcttca cgagcgtaga attcgcttga tttgtaagct gcttttgcgt
    24421 aaaggtcgat aacagtttct gaatcttcac cgaagatgta gatgttttct tctccaacca
    24481 actcagcgat ttccacgtta gcaccgtcca tagtaccaag tgtcaaagct ccgttcaaca
    24541 tgaatttcat gttaccagta cctgaagctt ctttagaagc aagtgagatt tgttctgaga
    24601 tatcacatgc tgggataagg aagcttgctg cagtaacgtt gtagttttca accataacta
    24661 cttgcaagtg tggagctact gctggatcgt tagcaataac ttctgacatg caaaggatca
    24721 agtgaatgat atcttgagcg attgtgtagg ctggagctgc tttaccacca aagaagattg
    24781 tgattggacg agcagggatg ttaccagctt tgatgtcaag gtatttgtgg atcacgtaca
    24841 aagcgttcat ttgttggcgt ttgtactcgt gaagacgttt gatttggata tcaaagatag
    24901 aatttggatt gatttccaca ccttggtgtt ctttcaagtg acgagccaat ttacgtttgt
    24961 tgtgagcctt gatgctttcc aatttttctt tgacagctgc tttgtcttca taagacaaca
    25021 gtttttcaag ctcatctgct tcatggtgcc aaccatctcc aagaatctca tccaagtagt
    25081 gagacaatct tgggttagca tgcataagcc aacgacggaa agtgataccg tttgttttgt
    25141 tgttgaactt ttctgggtaa aggtcgtaga aggctttcaa ctcagaattt ttcaagattt
    25201 cagtatggag tgctgcaacc ccgttaacac tgtatccgta gtggatatcc atgtgagcca
    25261 tgtgaacacg tccgctctca tcgatgattt gaacagctgg atctttgtac tctgccttca
    25321 cacgacggtc caattcttcg atgattggta ccaagtgagg aaccacttct tgcaagaatt
    25381 caagaggcca tttttcaagc gcttcagcaa ggattgtgtg gttagtgtag gcagtcatgc
    25441 tacgaacaat tgagattgct tcgtcaagat cgataccacg tgcagtcaaa agacgaatca
    25501 attcaggaat caccattgat gggtgagtat cgttgatttg gacaactgcg tagtcagcaa
    25561 ggtcatgcaa gttgcttcct ttttcgattg cttcgtcgat gatcaattgc gcaccgtttg
    25621 aaaccatgaa gtattgttgg aagatacgga gcaattcacc ttgacggtca ctatcatctg
    25681 ggtaaaggaa gagagttaag ttgcgagcga tatctgtctt gtcaaagttg ataccatctt
    25741 taataataga agaatcaact gaatccaagt caaacaaacg caagcggttt ttagtcgctg
    25801 tttcataacc agtaacatca atatcgtaaa gagttgatgt caaagtaaag tctgcaaatg
    25861 gtacttggta gctacggctt gagcgaacca accagttttg ctctgtcaac catgcatttg
    25921 gaattgtttc ttgttggttg tttttaagaa cttgttggaa aagaccaaag tggtagttaa
    25981 gaccaacacc gtcaccattc aaaccaagag tagcaattga gtcgataaag caggcagcca
    26041 aacgtcccaa accaccatta ccaagagatg gttccaattc aacttcttca acttcgatca
    26101 agtctttacc tgcagctgca agttcttttt taacatcgtc gtaaagacca aggttaatca
    26161 agttgtttga caagagttta ccaatcaaga actcagctga gatgtagtaa acttttttct
    26221 taccagtgtt gactggtttt tggctgcttg caagcttgct gtagttaaga agagcaaggt
    26281 aaagctcttc attgctacat tctgcaatgg ttttattgta acgattttgt acaaattctt
    26341 gtagtgataa catgtttagt tgtctcctga ttattgtctt atttctttaa atctaccaaa
    26401 ttttcattaa ttcggcgata aattgttgtc aagtcaagca aaccttcctc gacagctggt
    26461 gtcaattgat cttcagtcat acgccaagac cagtttccac caagggtaga tgggaagttc
    26521 atacgagctg cctcatccaa ttctagtaaa tcttgcatag ttgcaattgc cataaagcta
    26581 actgatgaaa atactgtacg aagcatagcg tgtaccactg tttcgtattc tttacggttc
    26641 gtgtaacgag ccatgtactc acgagtcgca tcatcaatct cattacggta ccaaccaaga
    26701 accgtattgt tatcgtgtgt tcctgtgtac ataactgagt tagcaggtgc caagtgtggg
    26761 ctatcaatgc tttcgtcttc tgggttgaag gcaaattgaa gaatcttcat tcctgggaag
    26821 ccagtacgtt cacgcaattc gatcacttca tctgtcatga agccaaggtc ttctgcgatg
    26881 atgtttagct caccaagttc ttccttaacg gctgcaaaaa gcttgtagcc tggacctttc
    26941 acccactcac caggtgctgc tgtatcggaa ccagcaggga tttcccagta agattcgaag
    27001 ccacggaagt ggtcgatacg aacgatatcg tagattttga agctttcacg caagcgttca
    27061 atccaccatt tgtagccgtc tttgtccatt gcttcccagt catagattgg gttaccccaa
    27121 agctgaccag ttacagaaaa ctcatctggt gggcatcctg cgatacaagt agccttacca
    27181 ttgacatctg ttttgaagag atgtggattt gcccacatat cacttgaatc ttccgctacg
    27241 tagattggca tgtccccaac gatttcgatg tggttgtcgt tagcgtaagc tttcaatttc
    27301 aaccattgtt ggaagaagaa gtattgagtc acacggtggt aaaccaactt gtctgccaat
    27361 tgctcacgat agctttcaag tgctgaagct ttacgagcac gagcatctgc atctggccat
    27421 tcagtccaag caagattgtc aaaatactct ttgatagcca tatactcagc aaagagctca
    27481 agccatgatt ggttgtcttg agcaaatttc tcaaaatctt taacatctcc gacttcaaag
    27541 aaacgtttca ccgctttttc taaaagagga cgacgtgcat agtagatttt agcatagtca
    27601 acttcagacg catcgctacc aaagtcaact ccttcaaggt cacttgcttc caacaaacct
    27661 tgctccacca agatatctaa atcgataaaa tgagtgtttc ctgcgaaggc tgagaaagat
    27721 tggtaaggag aatccccgta actagttgct cctaatggaa ggatttgcca gtaacgttgt
    27781 tttgtacgga ccaagaaatc aacgaagtcg taagcacttt gaccaaatga tccgattccg
    27841 taagctcctg gaagagaaga gatgtgcatc aacacaccac tttgacgttt tttcataata
    27901 gcacctcgtg tgttaaaata atggaacgtt gcgtattttg cagacgcaaa cgtttgcgtt
    27961 acttataagt atactccttt tcaagcataa ttgcaagcgt ttttaaaaaa cttttttgat
    28021 tatttttaag gaaactaact cattttagca aagataactt aaaactatct aatcctaagg
    28081 tttgactctc acgagacagt ctacaaagta taaaacctcc ttagggagct tgaatttata
    28141 tgtaacaaag cacaaacgtc tatagaaaat agatatagat tagaaacagg gaggtagccc
    28201 ctcctgattt ccctctttag acagattcca tatattttta ttaaaaatac tgtattctta
    28261 tctatttcat acttttcttc tattaaaatg caaaattatg ctatcaaatc aagcttaaaa
    28321 attttttaaa atttttacaa aaaatacttg caaccgtttt ctatttgtgc tatactaagc
    28381 tcataaagga aaacgtttgc gtttccttat caataaaact tgctattctt taggaggaat
    28441 acactatgtc atctaaattt atgaagagca ctgcggtgct tggaactgct acacttgcta
    28501 gcttgctttt ggtagcttgc ggaagcaaaa ctgctgataa gcctgctgat tctggttcat
    28561 ctgaagtcaa agaactcact gtatatgtag acgagggata taagagctat attgaagagg
    28621 ttgctaaagc ttatgaaaaa gaagctggag taaaagtcac tcttaaaact ggtgatgctc
    28681 taggaggtct tgataaactt tctcttgaca accaatctgg taatgtccct gatgttatga
    28741 tggctccata cgaccgtgta ggtagccttg gttctgacgg acaactttca gaagtgaaat
    28801 tgagcgatgg tgctaaaaca gacgacacaa ctaaatctct tgtaacagct gctaatggta
    28861 aagtttacgg tgctcctgcc gttatcgagt cacttgttat gtactacaac aaagacttgg
    28921 tgaaagatgc tccaaaaaca tttgctgact tggaaaacct tgctaaagat agcaaatacg
    28981 cattcgctgg tgaagatggt aaaactactg ccttcctagc tgactggaca aacttctact
    29041 atacatatgg acttcttgcc ggtaacggtg cttacgtctt tggccaaaac ggtaaagacg
    29101 ctaaagacat cggtcttgca aacgacggtt ctatcgtagg tatcaattac gctaaatctt
    29161 ggtacgaaaa atggcctaaa ggtatgcaag atacagaagg tgctggaaac ttaatccaaa
    29221 ctcaattcca agaaggtaaa acagctgcta tcatcgacgg accttggaaa gctcaagcct
    29281 ttaaagatgc taaagtaaac tacggagttg caactatccc aactcttcca aatggaaaag
    29341 aatatgctgc attcggtggt ggtaaagctt gggtcattcc tcaagccgtt aagaaccttg
    29401 aagcttctca aaaatttgta gacttccttg ttgcaactga acaacaaaaa gtattatatg
    29461 ataagactaa cgaaatccca gctaatactg aggctcgttc atacgctgaa ggtaaaaacg
    29521 atgagttgac aacagctgtt atcaaacagt tcaagaacac tcaaccactg ccaaacatct
    29581 ctcaaatgtc tgcagtttgg gatccagcga aaaatatgct ctttgatgct gtaagtggtc
    29641 aaaaagatgc taaaacagct gctaacgatg ctgtaacatt gatcaaagaa acaatcaaac
    29701 aaaaatttgg tgaataaaaa atttgttcaa ggggggtgga aatcaaatcc ccctttgaat
    29761 ttatcaatag agacacaaat aatttagctt tcttataaaa aagtagtatc ctatgaaagg
    29821 agttaatatg gaaaagcaac aacctagtaa agcagccctg ctgtctatca ttcctgggtt
    29881 aggacagatt tacaataaac aaaaagccaa aggttttatc ttccttggtg taaccatcgt
    29941 atttgtcctt tacttcctag cacttgcaac ccctgaattg agcaacctca tcactcttgg
    30001 taacaaacca ggtcgtgata attccctctt tatgctgatt cgtggtgcct tccatctaat
    30061 ctttgtaatc gtttatgtac tcttttattt ctcaaatatc aaagatgcac atacgattgc
    30121 aaaacgcatt aacaatggaa ttccagttcc acgcacactc aaagacatga tcaaagggat
    30181 ttatgaaaat ggcttccctt acctcttgat cattccatct tatgttgcca tgaccttcgc
    30241 gattatcttc ccagttatcg taaccttgat gatcgccttt accaactacg acttccaaca
    30301 cttgccacca aacaagttgt tggactgggt tggtttgacc aactttacaa acatttggag
    30361 cttgagtacc ttccgttctg cctttggttc tgttctttct tggactatca tttgggcttt
    30421 ggcagcttct actttacaaa tcgtaattgg tatcttcaca gctatcattg ccaaccaacc
    30481 atttatcaaa ggaaaacgta tctttggtgt tattttcctt cttccttggg ctgtcccagc
    30541 cttcatcact atcttgacat tctcaaacat gtttaacgat agtgtcggtg ctatcaacac
    30601 tcaagtattg ccaatcttgg ctaaattcct tcctttcctt gatggagctc ttattccttg
    30661 gaaaacagac ccaacttgga ctaagattgc cttgattatg atgcaaggtt ggctcggatt
    30721 cccatacatc tacgttttga ctttgggtat cttgcaatct attcctaacg acctttacga
    30781 agcagcttat attgacggtg ccaacgcttg gcaaaaattc cgcaacatca ctttcccaat
    30841 gattttggct gttgcggcac ctactttgat tagccaatac accttcaact ttaacaactt
    30901 ctctatcatg tacctcttca atggtggagg acctggtagt gtcggaggtg gagctggttc
    30961 aaccgatatc ttgatctcat ggatctaccg tttgacaaca ggtacatctc ctcaatactc
    31021 aatggcggca gctgttacct tgattatctc tatcattgtc atctcaatct ctatgatcgc
    31081 attcaagaaa ctacacgcat ttgatatgga ggacgtctaa gatgaataac tcaattaaac
    31141 tcaaacgtag actgactcaa agccttactt acctttacct gattggtcta tcaattgtaa
    31201 ttatctatcc actgttgatt accattatgt cagcctttaa agcaggtaac gtctcagcct
    31261 ttaaactaga tactaatatc gacctcaatt ttgataactt taaaggcctc ttcactgaaa
    31321 ccttgtacgg tacttggtac ctcaacactt tgattatcgc cttaattacc atggctgttc
    31381 aaacaagtat catcgtactt gctggttatg cttacagccg ttacaacttc ttggctcgta
    31441 aacaaagttt ggtcttcttc ttgatcatcc aaatggtgcc aactatggcc gctttgacag
    31501 ccttcttcgt tatggcgctt atgttgaacg cccttaacca caactggttc ctcatcttcc
    31561 tctacgttgg tggtggtatc ccgatgaatg cttggctcat gaaaggctac ttcgatacag
    31621 tgccaatgtc tttagacgaa tctgcaaaac tagacggtgc aggacacttc cgccgcttct
    31681 ggcaaattgt tctaccactt gttcgcccaa tggttgccgt acaagctctc tgggccttca
    31741 tgggaccttt cggggactac atcctctcta gtttcttgct tcgtgagaaa gaatacttta
    31801 ctgttgccgt aggtctccaa accttcgtta acaatgcgaa aaacttgaag attgcctact
    31861 tctcagcagg tgctatcctc atcgcccttc caatctgtat tctcttcttc tttctacaaa
    31921 agaactttgt ttcaggactt acaagtggtg gcgacaaggg ataatttatc cccgccaccc
    31981 tttttcattt tatactcttc gaaaatctct tcaaaccacg tcagctttat ctccaacctc
    32041 aaagttgtgc tttgagcaac ctgcagctag cttcctggtt tgcactttga ttttcattga
    32101 ttattagcaa ttgtcactgt aaataatatc cttgtagcaa gcaatttttc tcctagactt
    32161 gaaataaagc gcatttctct atataataat actcatatag aaaacacctt ttagaaagat
    32221 acctatgctt ccatatccat tttcctattt ttcaagtatt tgggggtttc gtaagcccct
    32281 gtccaaacgt ttcgagctca actggtttca acttctcttt accagtatct tccttatcag
    32341 cttgtctatg gtacccattg ctatccaaaa cagctcccag gagacctatc cgctagaaac
    32401 ttttatcgat aatgtctatg aacctctgac aaatgaggtt gtccaggatc tctctgaaca
    32461 tgctacaatt gtcgatggca cattaactta tactggaaca gctagtcaag ccccttctgt
    32521 tgtgattggt ccaagtcaaa tcaaggaatt acctaaggac ttgcaactgc atttcgatac
    32581 aaatgaacta gtcatcagca aggaaagcaa ggaactgacc cgcatctctt accgagccat
    32641 tcagactgag agtttcaaaa gcaaagacag cttgacccaa gcaatttcta aagactggta
    32701 ccaacaaaat cgtatctata tcagcctctt cctagttctc ggtgcgagct tcctctttgg
    32761 tttgaatttc tttatcgtct ctctaggagc tagtcttctc ctttatatca ctaagaaatc
    32821 acgcctcttt tcatttagaa cctttaaaga gtgctatcac tttatcttga actgtttagg
    32881 attgccgact ctgattacac ttattttggg attatttggc caaaatatga caaccctgat
    32941 tactgtacaa aatattcttt ttgttctgta tctggtcact atcttttata aaacacattt
    33001 ccgtgatcca aattaccata aataggagat ttttatgccc gttacgatta aagacgtggc
    33061 caaggctgct ggtgtttcgc cttcaaccgt aacccgtgtt attcaaaata aatcaaccat
    33121 tagcgacgaa acaaaaaaac gcgttcgcaa agctatgaag gaactcaact accacccaaa
    33181 cctcaacgct cgtagcttgg taagcagcta tactcaggtt atcggattag ttcttcctga
    33241 tgactcagac gccttctacc agaatccttt ctttccatcg gttctacgtg gcatctctca
    33301 agtcgcatct gaaaaccact atgccattca gatagcaaca gggaaagatg agaaggagcg
    33361 tctcaacgct atttcacaaa tggtctacgg caagcgtgta gatgggctaa tctttctcta
    33421 tgcccaagaa gaagaccctc tcgtaaaact cgtcgcagaa gaacagttcc ccttccttat
    33481 cttaggtaaa tctctatctc ctttcatccc acttgtcgac aacgacaatg ttcaagctgg
    33541 ttttgatgcg actgaatatt tcatcaaaaa aggctgcaaa cgcattgcct ttatcggagg
    33601 aagtaaaaag ctcttcgtga ccaaagaccg tttaacaggc tatgaacagg cgcttaaaca
    33661 ttacaaactt accactgaca acaatcgcat ctactttgcc gacgagtttc tggaagaaaa
    33721 gggctataaa tttagcaagc gattattcaa gcacgatcca caaattgatg ctatcatcac
    33781 aaccgatagc ctcctagctg aaggcgtttg taactatatt gccaaacacc agctggatgt
    33841 ccctgttctc agctttgact cggttaatcc caagctcaac ttggcagcct atgtcgatat
    33901 caatagttta gagcttggtc gtgtttccct tgaaactatt ctccagatta ttaatgataa
    33961 taaaaacaat aaacaaattt gttaccgtca attgatcgcc cacaaaatta tcgaaaaata
    34021 agagactggg caaaaagtcg ttaaaagcaa aaacgcatac tatcaggtat tgaaaaaact
    34081 tgatactatg cgttttaatg tgggaagatt tacttccttt tctactgaaa ttgagtcttt
    34141 tcccaagatc tttttatact caatgaaaat caaagtgcaa actaggaagc tagccgcagg
    34201 ttgctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagct caaaacatgg
    34261 ttttgaggtt gcagatagaa ctgacgaagt cagtaacata tatacggcaa ggtgaagctg
    34321 acgtggtttg aagagatttt cgaagagtat taatcactaa ttatctatct caacaaatct
    34381 tcctagaata tgaacatttt ccgagacaga gacaaaggag cttggatcca cttgtgtcat
    34441 aatctgttta aattcattaa actctgcacg tgtaatgaca gtgattaaaa ctgcctttct
    34501 ctcgtgatta taggttcctt ctgcatcgtg gatcatggtt gctccgcggt gcaatttttt
    34561 atggattttt tcaattacct tctctggatg atttgtcaca atcatggcct gcatacgctt
    34621 ttgcttagta aagactgcgt ctgtcacacg gctagagaca aagatggtaa tcatagaata
    34681 aagagcgtat ttccaaccaa aggtcaaacc tgctatcagc atgatagttc catttaccaa
    34741 gaaagaaata ctaccgacat tcttacccgt tttcttacga atagtcaggc tgacgatatc
    34801 cgtcccacca ctggagatat tgtttcgaag agcaaaacca atccccaaac ccataacaac
    34861 acccccaaaa agggaattga taatgggatc ctccgtcaag gttgccacag ggacaaactg
    34921 gataaagaag gaactcatag ataccgtgat aaaggtaaag acggtgaact tatggccaat
    34981 ctgataccaa gctaagacca tcaaagggaa gttaatggcg tagaagctta gcgaaatcgg
    35041 aatatgaaaa ccaaaccagt gattactcaa ggcagagata atctgtgcca gacctgttgc
    35101 accactcgaa tacacatgcc ctggttggaa aaagaaatta actgctactg ctgataaaaa
    35161 accatagacc agagaggccg aaatcttctc atcatacttt tctcgagaga tactttgtaa
    35221 gacacgtaaa atttttatct gataagcaaa gcggcgcaga taatagcgcc accgcttaat
    35281 tcgttttgtt tgtttcatct tcttctactt gtaagctgag ttcctctagt tgtttgagag
    35341 cgactgttga tggagcttgt gtcattgggt cagttgcctt gttgttctta ggaaaggcaa
    35401 tgacttcacg gatattttct tctccagcaa gcaacatgac aaaacggtca agcccgatag
    35461 ccaaaccacc gtgcggtggg aaaccatagt ccatggcttc aagaaggaaa ccaaactggt
    35521 cattggcttc ttcagttgag aaaccaagag ccttgaacat gcgttcttga aggtcttttt
    35581 ggttgatacg aaggctacca ccaccaagct cataaccgtt caagacgata tcgtaagcaa
    35641 tggcacgaac cttagccaaa tcaccttcta attcgtgagc agtctcttcc tgtggaagtg
    35701 tgaatggatg gtgggcgctc atgtagcggc cttcttcttc agaccattca aacatcggcc
    35761 agtcaaccac ccaaaggaag ttgaacttat cattatcaat caagccaagc tctttagcaa
    35821 tacgtccacg aagggtaccc agtgttgcat taaccacttc aagcgtatcc gccacaaaga
    35881 gaaccaagtc cttatcttca agagcaagcg ctgttgtcaa ttcttcttgg ataccagtca
    35941 agaacttggc aactggtccg tttaattctc catcaaccac cttgacccaa gcaagacctt
    36001 tggcaccata ctgtttggct acttccgtca tcttgtcgat gtctttacgt gaatagttgt
    36061 ccgcagctcc tttgaccaca atcgctttta cagcaggtgc ttctgaaaag actttaaagt
    36121 ctacaccttt gaccacttct gtcaagtcct gaagcaacat gtcaaaacga gtatctggct
    36181 tgtcagaacc gtaaagagcc atagcatcat cgtatttcat acgagggaac ggtagcgtta
    36241 cttcgatgcc ttttgtttcc ttcatcacgc gcgcgatcaa gccttctgta atatcttgga
    36301 tttctttctc agtaaggaag gacgtttcca agtcgacctg agtaaattca ggctggcggt
    36361 ctccacgcaa gtcctcgtca cggaaacatt taacgatttg gtagtaacgg tcaaaaccag
    36421 cattcatcaa gagctgtttc gtgatttgtg gactttgagg aagagcgtaa aaatgcccct
    36481 tattaacacg agacggcact aaataatcac gcgccccttc aggcgttgac ttagaaagga
    36541 atggtgtctc cacgtcgata aactccaact catccaaata gttgcggata gagtgggtca
    36601 ccttggcacg aagtttaaga ttttccaaca tttctggacg acgaaggtca aggtaacggt
    36661 aacgcaaacg tgtatcgtca tttgcctcaa tgccatcctt aatctcaaat ggtgttgtct
    36721 tagctgtgtt aagcacaata agagctgtca cgtttaactc aaccgcacca gttggcaact
    36781 tatcattggc ttgctcacgc gcagcgacct gaccagtcac ctcaataaca aattcgctac
    36841 gaaggctttc agctgttgcc ataacctctg cagatacttt ttcagggttg ataaccaact
    36901 gcatgattcc ttcacggtca cgaagatcga taaagatcaa accaccaagg tcacgacgac
    36961 ggccaaccca tcctttcaag gttatttctt gtccgatgtg ttcctcacga acacgaccag
    37021 catacatact acgtttcatt atttctctcc tcttttattc tgttactatt ttaccataaa
    37081 agcgcaggct cttcatgaaa atcatcagaa aagtttgcca gtctttaaaa gtcaggtgaa
    37141 agccctaaaa attagcgcta atactcttcg aaaatctctt caaaccacgt cagcgtcgcc
    37201 ttaccgtagg tattgttact gacttcgtca gtttcatcta caacctcaaa accatgtttt
    37261 gagctgactt cgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct
    37321 agcttcctag tttgctcttt gatttttatt gagtataaaa tcctagtttt tcaaagattt
    37381 ctgagaagtt ttggctgatt gtctcaagtg acacttgcac ttcttctcgg gtttggttgt
    37441 tcttgaccgt cacttgtccg ctttcgactt cgctctctcc tagggtgatg agggtcttag
    37501 ccgcaaagac atcggctgac ttgaactgag cttttagttt acggttgagg taatcacgct
    37561 ctgctttgaa accttgttgg cgaagagcct gtaccaattc caaggccttg atatttgccc
    37621 cttcgcccaa gactgcgata tagacatcta gggcgttttc gatagggagg gtcacacctt
    37681 gcttttcaag gatgagaagc aggcgctcta caccaagtcc aaaaccaaat ccagcagttt
    37741 cagggcctcc aaagtaagca accaaaccat cgtagcgacc acccgcacag acggtcaggt
    37801 cattgccctc aatctctgtg ataaactcga aaatggtgtg gttgtagtag tccagaccac
    37861 gcaccatatt ggtatcgatg atgtaatcta ctccaagatt ttccaacatc tgacgcacag
    37921 catcaaaatg agcttggctt tcttcatcaa gaaagtccaa gatagacggc gcattctcta
    37981 ctgccacctt gtcttctttt tccttagagt ccaagacacg aagaggattt tcctccaagc
    38041 gacgttggct atccttagac aaggtctcct tgagcggtgt caaatagtca atcaaggctt
    38101 ggcggtaggc tgcacggctc tcaggatttc caagagtgtt gaggtgcaat ttgacacctt
    38161 gaataccgat ttccttcaaa aaatgggctg ccatagcgat tgtttccaca tcggtagctg
    38221 gattgctaga gccaaaacac tcaacaccaa tctggtggaa ttggcgcaag cgccctgcct
    38281 gtggacgctc ataacggaac ataggtccca tgtagtagaa cttgcttggc ttttgcactt
    38341 ctggggcgaa aagtttattt tccacatagg aacggacaac gggtgcagtt ccttctggac
    38401 ggagggtaat atgacggtca cccttgtcat aaaaatcgta catttccttg gttacgatat
    38461 ccgttgtatc tccgacagag cgactgataa cctcgtaatg ctcaaaaata ggcgtgcgca
    38521 cttctgcata gttgtagcgt ttgaaaatct cacgggcaaa gccctcaacg tactgccact
    38581 tagcagactc agcaggtaaa atatcctgcg ttccttttgg tttttgtaat ttcataggga
    38641 atcctcttta aacttaatag tcttatttta ccataaatag agggattaaa acagtaagaa
    38701 aaaaattagg atttagatat catttttgag attaagaatt gtcaaaaaaa tagctagcaa
    38761 ggaaagacca acaaatagca tccaagtcaa ctgtatattc catacggcta ctagtgaaaa
    38821 acaagctgtt cccacaggta tggataaggt aaacaataga cctaaaaaat tactagtacg
    38881 agctagaacc tctggagcta gatttttcat gagcatggca ctaatctttg gttgaacttt
    38941 accagacaca tacagagtaa agaagagaaa tagcaaacca agcacgactt gattgaataa
    39001 attagccaaa ccaactagac taagtcctac ggtctcccac atcatcaatc taggcaagga
    39061 ctgcttccca aaataatcat tgcccgtaag gctactgatg atgactgata ctaaaacaca
    39121 gaattgattg ataaatagtg cctctgtata agaaaaattc aagagagaat ggctcaaaaa
    39181 gaagatatta taaattccac ccaaagcgcc acccaaggaa ttaataagca agacagcaaa
    39241 gagcataaaa ccaaagtttt tctgtccact tttaagaaaa acgagacgta aatttcggta
    39301 aattgttagg aactggtctt tgatagaaag cttctcattt tttaagtttt caccatcagc
    39361 agatgacatt gacaggctca atttgctttt tcctaaaaag aggatagtgg ctgatactag
    39421 gaaaaagcag gcattgattc ccgcaacgag agaaaaattg ttgaccgata gagctaagag
    39481 ccagactccg aaagcttgac caccaatagc tgaaatatag gtgatgaact gtgaaaaaga
    39541 ataagcctcc atcagatcat cttcagctac tttttcctta ataagaggca tacgcaggcc
    39601 acctgcaaaa tcactgatga tatcactaat gacattgatc aaacacaggc tagaaaaggc
    39661 aaagagacta gcttgctgaa caactagggc tgctagaaaa aatagaaccg cctgaaacaa
    39721 accgctatag accatccatt tgaccttgtc cctcgtgtaa tctgcccgaa tccctgcaaa
    39781 aactgtaaag agggtcggaa gaatcatgac aatattcgcc atagcaacag caaaagatgc
    39841 ttgtgacaag gtcgatgcat agacgataaa gaccaggttg aaaatcgaaa caccaaaagc
    39901 attgaagaag cgtgataaag tcaaaattct ataagctgga tttctaaaca atagtttcat
    39961 agataatctc cctccttgtt ctaagttcta catcaagaat agctttagta tagcacttat
    40021 gaatttgcga aacgattctt ttgaatatat gcaacaaaca aaatgagcaa aaaaacgata
    40081 gaacttttgt aatgacctga gagagggcaa cagttctatc gcttcaaatt ttttcttggt
    40141 ttgcagatat tcaagaatcg ggagtttttc tatagtattc ggcagattta ttacagccaa
    40201 gcatctcaaa aatacggaca gcatcctcca tctttttctg gccttccttg actctacctt
    40261 gcttgctatc aaggagacct tctgcccaca gataaacaat tcggaaatag gtctcatttt
    40321 ccttgtagaa atgctcttcg ataacacgtt taaaataata ggcattggta aattcttcac
    40381 actcaatact agctaaaaag ccattcaata gtatagtatg aaaaaggttt cgattgccag
    40441 acatttccat tagaaaatcg gatttacgta ccatttctcg tacatatcta gtaaaaagag
    40501 aaacagataa aaatggagaa ctgactgaaa ataaattgag ttcatagatt ccccagatct
    40561 cggtagaaaa caaataatca tgaaggactt ttccttcctc tgctgttaag tctacccttt
    40621 catctatgct cttcatataa gacttgataa taatggcatt tagaatatgt ttctgtttgt
    40681 tgtgagaatg ggcatgcttt tatactccct gcgatataag tcctcaagag gtgctatatt
    40741 ctttggttcc aagacatctg taatttcttt tctcaactca gaatctgtat catactggaa
    40801 acctcttgcc agaaagagga tctcctccac actggcagat atattttcca gagcaaatag
    40861 aaacttttcc accgaaagct cactctgacc tgtttcaaaa cgggacaaca tagacggcga
    40921 aaattgtcct ccggttgctt gtctcagtga gatatttctt gactctcgta attgtctaaa
    40981 gacttttcca atctgctcca tagacttccc cttgattccg tattttcttc attttatcat
    41041 atttttcaga aaattcatca aaaacttgcc aaattgtcag aattatgaga aaatagagga
    41101 tatttatcac gtggagggac tgctatgaga gacgatatca aaatcaatga ccgtgctttg
    41161 gccttgcaag accaaattat cgaaaaacta gagaaagttt ttgatacaga tgtggaattg
    41221 gatgtttaca atctaggtct gatttatgaa atcaatctgg atgaaacggg gctctgcaag
    41281 attgtcatga ccttcaccga tactgcctgt gattgcgccg aaagcctgcc tattgaaatc
    41341 gtggcaggtc tgaaacaaat cgagggtatc aaagatatca aggttgaagt tacctggtcg
    41401 cctgcttgga aaatcacacg aatcagtcgc tatggccgta ttgcccttgg actaccacct
    41461 cgttaagcag accaatcact tttaaagatg aaaaaagcaa gccgaaaatg gcttgctttt
    41521 tgatactcaa tgaaaatcaa agggcaaact agaaaactag ccgcaggttg ctcaaaacac
    41581 tgttttgaag ttatggatag aactgacgaa gtcagctcaa aacactgttt tgaggttgtg
    41641 gatagaactg acgaagtcag ctcaaaacac tgttttgagg ttgtggatag aactgacgaa
    41701 gtcagcccaa aacactgttt tgaggttgtg gatagaactg acgaagtcag taaccatacc
    41761 tacggcaagg cgacgttgac gtgatttgaa gagattttcg agtatgagtt tattttttac
    41821 ctgacttgtc catattccag aagtctgtca cggctccgcg tgaagcagat gatacgatgt
    41881 gggcatattt accgaggaca ccacggctgt aaagtggtgg caaggttgtt tctgccttgc
    41941 gtttttcaag ttcttcttcg gatacggcca tagaaatttc tttggtatct tggtcaaccg
    42001 taacgatatc gccggtacgg agataggcaa ttggtccacc atcctgagct tcaggagcga
    42061 tatgtccaac aaccagacca taagtaccac cagagaaacg tccgtccgtc aagagggcca
    42121 ccttatctcc ctgaccttta ccaacaatca ttgaagaaag tgatagcatc tcaggcatac
    42181 caggaccacc tttaggtcca acaaaacgaa caacgactac atcgccatca acgatttcat
    42241 ctgtcagaac ggcctgaatc gcatcttctt ctgagtcaaa gaccttagct ggcccaacgt
    42301 gacgacgcac tttaacacct gataccttgg caactgcacc gtcaggagca aggttcccgt
    42361 tcaagatgat aagcggacca tccgcacgtt ttggattttc aagtggcatg ataacttttt
    42421 ggcctggagt caagtctgca aagtcagcca agttttcagc tacagtctta ccagtacatg
    42481 tgatgcgatc tccgtgaagg aaaccatttg ccaacaaata cttcataacc gcagggacac
    42541 caccgacttc gtagaggtct tggaagacat actgaccaga tggtttcaag tcggccaagt
    42601 gaggcacacg ttcttgaatc gtattgaagt cctcaagtga caagtcaaca tttgcggcat
    42661 gggcaatggc gagcaagtga agagtggcgt ttgtagaacc accgagagcc atcgttacag
    42721 tgatagcatc ttcaaaggct tcacgagtca agatatctga tggtttgaga ccaagttcca
    42781 acatcttaac aacagcacgt cctgctgctt cgatatcttc tttcttatca gctgattcag
    42841 ctgggtgaga ggatgaccct ggcaaactca tccctagaac ttcgatagca gttgccatgg
    42901 tattagcagt atacatacca ccacaaccac cagggccagg gcaggcatta cattcaagac
    42961 gtttcacgtc ctcagctgtc atgtcaccgt ggttccattt tccgatacct tcaaagacag
    43021 aaaccaagtc gatatcttta ccatcaagat ttcccggtgc aatagttcca ccataggcga
    43081 aaatagctgg gatatccata ttagcaatag caatcataga tccaggcatg ttcttgtcac
    43141 agccaccgat agcgacgaag gcatccacgt tgtgaccact catagccgcc tcgatggagt
    43201 ccgcgatgat gtcacgagat gttagagaga aacgcatacc aggcgttccc atagcgatcc
    43261 cgtccgctac ggtaatggtt ccaaactgta caggccaagc gcctgcagat ttgacacctt
    43321 ctttagccag tttcccgaaa tcatgcaagt gaatgttaca tggtgtattt tccgcccaag
    43381 tcgaaatcac tcccacaatc gatgtttcaa agtccttatc tgtcatacca gtcgcacgaa
    43441 gcatagcacg gttaggtgat ttaaccatgc tgtcataaat gctactgcgg tgacgtttat
    43501 ctaattcagt catcttatcc ctcccatttc agtttttact attatagcac aattttcgca
    43561 tgaagaacag aataaaattc ttgaattttc agaaaattct atacacatgt gaaatattta
    43621 aaattaaaaa caacaaagcg gattagtgca ctttctgatg accagaatat gctttttaat
    43681 ccgctttctt taaataacgt actgtaattt ttacagaaat tctttcaaat aagtgtattt
    43741 aacatctatc ttgcattata aatttctaga accttctctt ttatattcga ttcactcaaa
    43801 ccatactcat taagaagata atccattttc cctacttgac cgaatctttc ttgaacaccc
    43861 atccgatgaa tttttgttat tccatcatca gagaataatt cacataaagc actgccaatt
    43921 ccacctatct gattgtggtt ttctacagta aatatagttt ttccacttaa cattgttttt
    43981 atctgttctg gtatcggttt gattctaaat aaatctatca cacctactga ataacctaat
    44041 ttagacagtt catctgcaac tcgaatactt ggagcaacca ttatgccaga agcaacgatt
    44101 acaagatctt caccatgcct taactcaatg tagcctttag aaaaatcttc tccaccttga
    44161 tacacaggaa ctggagcttt tctaattgtt cgaatatatt ttagtccttt taagtctaat
    44221 gtctggttca atatttcacg aaattggata tcatcagttg cttcgaaaat gattgattta
    44281 ggaattaaac gtaacaatcc aatttcttca aatggcatat gtgttccacc attcatctct
    44341 gccgttactc ctgcatctga tccaatcaca gtggcatcca attgtgcgta tccaagagaa
    44401 ataaataatt gatcaaatac tcttcgtgaa gcaaaaggac caaatgtatg aagataaggt
    44461 ctaaacccct gaatagacaa gcctgctgca aggccgacca tttctgcttc cataatccca
    44521 acattcacat aacggtctcc aaagtccttt tcaagattat tagtagccat cgaacttgac
    44581 aaatcggctt ctaagactac tatatcagaa tcactttgat tagcctctaa aaggaagtct
    44641 ctatatacat gccgtaattc tttcgtactt ctcatcattc tgtttcctcc aattcctgac
    44701 ttaatctttc tacaactgaa gttaacattt gtttctcctc tacagtaggg cgaagatgat
    44761 gattggattt catttcttcc agctcttgaa ccccttgacc tttaatagta tctaatacaa
    44821 tgcacttagg tgatgaatta tttgactgtt ttaattggac aatcccttca taaatttctc
    44881 taatatctga acccttgacc ctaatggatt caaatccaaa tgctgaaaat ttttctacga
    44941 aatcacctgg attacaaata tcctttgtaa aaccatctaa ttgttttttg ttatcatcaa
    45001 caaatacaat taagttggat aactgttgat gagaagcaaa ctgtatagcc tcccaacatt
    45061 gtccctcatt taactcacca tctccaacaa tagcgtaagt ataaaaggga ctctttctta
    45121 ttctctgacc atatgcaagt ccagttgcaa cactaattcc ttgtcctaaa gagcccgttg
    45181 tcatatctat gcctggcgtt agatttctat caggatgaga cggtaatttg gttccatttg
    45241 tatttaaaga atataagaat tctttgtcaa agaaaccatt caaatagagt gtactgtata
    45301 gagctggtcc tccgtgacct tttgataata tgaaataatc tctatctcgt gctgcaaata
    45361 tttctggagt cattggcatt atttcaccat aaagcaccgc taaaacttct acgatagaca
    45421 gacttcctcc gtaatgtccg aatccaagat gattcaatgt tctaagagta tttaatcgga
    45481 tgttagtcgc aaattttctt aacccatctt ctctattttt acttaaaatc atcccttatt
    45541 cctccgttgc agatggcttt ttaataaagg atactccaaa cataactgct agaataagaa
    45601 caagaccaat cacaatgcct gcttgtgagc caaattgatt taacattcct aaaataattc
    45661 ctgatagacc aaaatctgca tctgagaaag ttgatccttg gaaaccaagt cctcccaaaa
    45721 ctggcattaa aaagactgga agaaaactga ttaaaatacc ttgtaaaaat gctccaatag
    45781 tggctccacg aacaccacca gatgcattcc caatgacacc tgcagtcgct ccacagaaga
    45841 aatgaggcac aacacctggt aagataacaa ccgttcctga agcaatcata attaccatac
    45901 ttactaaacc accaacaaaa ctagagataa atccaattag aactgcattg ggtgcataag
    45961 tataaacaat cggacaatcc aaagcaggtt ttgaattagg tacaagacgc tctgaaatac
    46021 ctttaaaggc tggaacaatt tcgcccaaaa taaggcgaac acctgctaaa ataacaaata
    46081 cccctgctgc aaattgacct gctaattgta aagcataaac tagaccactt gtaccactac
    46141 tgatttcttt ttctatatat tctgaccctg caaagatagc tacaataatg taaataactg
    46201 ccatggataa agtaatacta acagtactat cacgtaaaaa agctaaactc tttggaaatt
    46261 taatgtcctc tgttgatttt gatttgtcac cgataaggct accagtaaaa ccactcaacc
    46321 aatatcccaa agaactgaaa tgacctaaag ctaccttgtc atttccagtt aattgaacca
    46381 tatatttttg cacaaatgct ggggaaatac tcataataat accgagtgct aatcctccta
    46441 gtaagatgag aggcaagcta gtaaagccag caactgataa aatgaccgca atcatacatg
    46501 ccatatatag agtgtggtgc cctgttaaaa aaatatattt aaatcgagta aaacgagcga
    46561 ttaagatatt gaacaccatg cctgcaaaca taatcattgc agtagctgag ccatatgttg
    46621 ttaaagctac agctacaatt gcttcattat tcggcacaac gccagataaa tgaaaagcat
    46681 gctcaaacat ggtaccaaat ggatttaaag aattttgtac aattcctgca ccaccagata
    46741 caactaagaa accaacaaag gtcttaattc cacctttaat aatatcaggt aatttcttct
    46801 tctgaagaac taatcctaag attgcaatta aagctactaa aatagctggt gtactaacaa
    46861 tatccaatat gaacttcatc atgacgctag cctcctatat aagtcctttt tcttcacaaa
    46921 gtttagtaat taattctcgt agttcatcca tatcaataat actatttaag atacgaacat
    46981 ctccaagatg actagctgaa tcagctagat cacgaccaac aatccaaata tcagctgcat
    47041 ttggatctgc tccacctaaa tcataatgtt caacttctac atccgaaaca ttcaaatcac
    47101 tcaatacaga ttcaatattc atctgtacca taaaacttga acctaatcct gaaccacaag
    47161 ctgtaccaat ttttaacatt atctaatcct cctgtttaat tatcatttta atgtcatcat
    47221 agttttttga tgatattaaa gtttgaacat gatttttatc tcttaaaatt gttgttaaat
    47281 gtgacaaagc ctttaaatga ctctcattat caatggctgc aatacaaatc aacaatctta
    47341 cctcttgttc tggattatcc aataaataaa tcggttcttc caaaactaac attgacattc
    47401 ctatttcatt cacaccttca tctggccgag cgtgaggaat tgctactccc ttccctaaat
    47461 taataaaagg tccaaactct tctacttttt gaatcattgc ctcagggtag ttctcagtta
    47521 tcttatcttg atccaaaagc ggtttagctg ctaaacgaat cgcctccttc catcctaatt
    47581 tttgcgaact aacctgatag gtttctttgg taataagttg ttctagcact ggtacaattt
    47641 cctttctatc atttttttgg taaagataat tctttaacgc caatcttaat tccaattctt
    47701 gtgtaataat tccatatctt ttgacaatat tcaggatttg ttcaatctca aaatctccat
    47761 actctaaatt cggaaaatct tttaacacta gttctactag ttgtattgct tgctcttcag
    47821 tcatcataac cgaaactaga taatttggct tttctgtctc cacctttatg gtagaaaaaa
    47881 ccatatcata gtcactacta gctttcacct gtaaatcatc aatctttgag gttcctataa
    47941 actcaatttg aggaaataat gctaatagat tctcttttaa catcaatgaa gaactaacac
    48001 cattaggaca aatgattgct gctttatacc atttttgagg caaagtatct gctttcttta
    48061 aataacctcc gaaatggata acaaaatatg ctgtttcact atcaggtatg ggattgtcaa
    48121 tagcgtccat caagggcatc aaagaatctt tgactaattc aaataaatca ggataatgtt
    48181 ctttaacatg caatacatat tcatttgaac taggtaggcc gaactttaat ctatagtaag
    48241 ccggtataag gtggcggcga agattttctc tcaatccttc cctttgttta aaatgtaaca
    48301 aagaaatatc ttccattcta cttataatag cctctgttaa ttgattaaag taaaccggag
    48361 caacatctac ttcaccttca aagcaacttg ataataaaac ggtgatatag cgataatcat
    48421 cctcagaaaa caccgtatct ataattccca aatcaaccac tgtatccaat aaaatagtgg
    48481 ttatatcttg aataacagga gatactaatg tctctgaaag acatactctt tcaacatccc
    48541 tttgatacct acacagaatg aatactaaac cgaaaaggta aacttttaat tgattaacaa
    48601 taggtactag ctgtagcttc tcataataat ctttaactac ctgatcaatc aaatcataag
    48661 ttaatgaata cccccaactg gataaaacat aatccaaacc ccaaatccct atggaggatt
    48721 ccagcaactc actaaccatt tgaaaagcta agcggtgctt attccactct gaaccgtgta
    48781 aagtataacc ttttgctcta ctgtacccta gctccaaatc attatctaac ataatctttc
    48841 ttaatgattg aatatcagat aaggttgtat tcttacttac tttcaaaaag tcttggtaat
    48901 gactattcga tataaaatct aatcggcaaa aagtgtaaag atagattaaa gctaagcgag
    48961 tcgactttgg taaaaccaat tcatccgact taataatatc tgtcaaagac tgcttcgtac
    49021 gatttgataa actatagcga ccttgctttt tatccagcac tatcccttta ttagctagat
    49081 aaggcactaa ataatctatt ccttctttga cttcctttat aggtaagctc accttaacag
    49141 ataattcata taatgatagc tcacaatgat ccatcaaagt catcaaaata actagtgctc
    49201 tataatcaaa catttctctt cctttctaac tacaattata gtgtaaaaat tataagaata
    49261 aaagagtatt tgagcacaat ataatctcac cttttaaaag aaattattgg gctgaaagtt
    49321 tttagtgatt atttttcaac tttctattga ctttataaat taaagtgata tcatttagat
    49381 atcaaataac aggaggtcat tcttatgact gaaaaactaa tcaattcaaa accaaatggt
    49441 gtattcgcat tgattctcat tgagttgaca atcgtacttg gtatctttat atttataatg
    49501 ggggttggtt cggaaaacat ttttggaatt attatcggac ctttactaat cgtaattgca
    49561 ggtctagctc atgctggttt aaaagttgtc aaacctcaag aagctctggt tctgacactc
    49621 tttggtaact atacaggtac catcaaagaa cctggctttt actttgtcaa tcccttcagc
    49681 gtagcagtca accctgcaaa ccacactcga cttggacaaa gtggtgatgt tagcacaaaa
    49741 tctccttttt taggagctaa atcatcaaat gacaatgatg taaatcttga aattggcaag
    49801 aaacagattt ccctcaaagt catgaccttg agcaattctc gtcaaaaaat caatgattgc
    49861 ttaggaaacc ctgtagaaat cggtatcgcg gtaacttgga gagttgtcga taccgctaag
    49921 gcagtcttca acgttgataa ctacaaagaa tatctttcat tgcaatgtga tagcgccctc
    49981 cgtaatattg tccgcatcta tccttacgat gtgtctccta atgtggatac tacgggtgat
    50041 gggcaagcag atgaaggtag tctccgtggc tctagcgaaa ttgttgctaa ccgtattcgt
    50101 gaagaaatcc aaagtcgtgt tgaggatgct ggcttggaaa tccttgaagc acgtatcact
    50161 tacctagctt atgctccaga aattgctgcc gttatgcttc aacgccaaca agcatctgcc
    50221 attattgatg cacggaagat gattgtagat ggtgctgtag gaatggttga aatggcacta
    50281 gaacggctca atgaagggga attggtagaa cttgacgaag aacgaaaagc tgccatggtt
    50341 tcaaatctcc ttgtcgttct ttgtggcaat catgatgcac aaccaattgt caacacagga
    50401 agcctttact aaagatggct gaagctaaaa aaaagcagat cccccttcga ctctcaacaa
    50461 agttatacgc tgcactcgca tcatgggcag aagacgactt tcgttcagtc aatgggcaaa
    50521 tcgaatatct cctcacagag tgtgtcaagc aacggaagaa agacggaaaa tacgtatcag
    50581 aaaccattga cgaaccattt gagattgata tttaacacct tctcctgtct gccgtgtcgg
    50641 ataggagaat tttttcatct ttttttgtca agtaacttta ctttacaaaa aaaatgtgtt
    50701 atcctagtat ggttgatgaa aatcagtaga ttgaatcgaa tataaatacc taaaggagaa
    50761 atcaaaatgg cagtacctgc acgtcgcact tcaaaagcga agaaaaacaa acgtcgtaca
    50821 cactacaaag taacagctcc atctgtaaac tttgacgaaa ctactggaga ttactcacgt
    50881 tctcaccgtg tatcacttaa aggatactac aaaggacgta aaatcactaa agctgcatca
    50941 gctgaataat agaagggaga taccatgcgc gtaaatatta cacttgaaca caaagaatct
    51001 ggtgaacgct tgtaccttac ttctaaaaac aaacgtaaca ctccagaccg ccttcaattg
    51061 aagaaatact caccaaaact tcgcaaacac gttgtgttta cagaggttaa ataagcattc
    51121 aatacgaatc aatacagaag aaaaacgctt gatcagcgtt ttttcttttt gttaatttca
    51181 ctacattgta agggaaatca ttcgaatgac tacatttttc actacctttt ttgaaataag
    51241 aatacggatt cggacaatta aaagcaagag gaactcaaat gtaagttggg gttccttttt
    51301 tgtatatttt tcaaataacg cctctacact atttgtagca aattcaccaa ctacagttgt
    51361 atcttagtta aaataagtta gaatatgtaa gtgagtacca gatataccaa gacatcgtca
    51421 ccatctaagg tatattcaaa atacaaaagt tgaccaacta gatttctgaa tatccttata
    51481 tatccattct taaaattggt ttaaatagcg tagtctttta aactagtttt gagaatccaa
    51541 aaaatcttcc tacatatgta agaagatttt ttagttcaga atgattagat ttagctaatg
    51601 gatacctatc ctacccactc accgttagca ttgactcgat agccatcggg tgtagtcgtg
    51661 tttactaata aatctcctga attataggta tagtaccatt taccagaaac tgtaacccaa
    51721 ccagtagcca ttgaacctga ttcatttaag ta
//
LOCUS       DAVAZV010000006        51676 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVAZV010000006 DAVAZV010000000
VERSION     DAVAZV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.006"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(54..362)
                     /locus_tag="VQT46_000341"
                     /pseudo
     CDS             complement(54..362)
                     /locus_tag="VQT46_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            complement(604..900)
                     /locus_tag="VQT46_000342"
     CDS             complement(604..900)
                     /locus_tag="VQT46_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370435.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQT46_000343"
     CDS             complement(884..3043)
                     /gene="pfbA"
                     /locus_tag="VQT46_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET2370436.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVISTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRESGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKESVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(4173..5399)
                     /locus_tag="VQT46_000344"
     CDS             complement(4173..5399)
                     /locus_tag="VQT46_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET2370437.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(5442..6134)
                     /locus_tag="VQT46_000345"
     CDS             complement(5442..6134)
                     /locus_tag="VQT46_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2370438.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(6320..8071)
                     /locus_tag="VQT46_000346"
     CDS             complement(6320..8071)
                     /locus_tag="VQT46_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370439.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(8061..9806)
                     /locus_tag="VQT46_000347"
     CDS             complement(8061..9806)
                     /locus_tag="VQT46_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2370440.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(10012..10308)
                     /locus_tag="VQT46_000348"
     CDS             complement(10012..10308)
                     /locus_tag="VQT46_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET2370441.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(10461..10917)
                     /locus_tag="VQT46_000349"
                     /pseudo
     CDS             complement(10461..10917)
                     /locus_tag="VQT46_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            11051..11878
                     /gene="xth"
                     /locus_tag="VQT46_000350"
     CDS             11051..11878
                     /gene="xth"
                     /locus_tag="VQT46_000350"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET2370442.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11890..12033
                     /locus_tag="VQT46_000351"
     CDS             11890..12033
                     /locus_tag="VQT46_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2370443.1"
                     /translation="MDYNAVIPEFLVSNIEQSRSFYCGLLGFRIEYQRSEENFLFLLK
                     SVN"
     gene            12033..12272
                     /locus_tag="VQT46_000352"
     CDS             12033..12272
                     /locus_tag="VQT46_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET2370444.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVPKLYQKVMEANYPI
                     YRPLTKRKFRVSDPYIYPHKFAVLDPDGYFLRFSE"
     regulatory      12656..12751
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            13151..13732
                     /locus_tag="VQT46_000353"
     CDS             13151..13732
                     /locus_tag="VQT46_000353"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET2370445.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAAAGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13732..14994
                     /locus_tag="VQT46_000354"
     CDS             13732..14994
                     /locus_tag="VQT46_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET2370446.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LSAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(15081..15947)
                     /locus_tag="VQT46_000355"
     CDS             complement(15081..15947)
                     /locus_tag="VQT46_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET2370447.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15934..16704)
                     /locus_tag="VQT46_000356"
     CDS             complement(15934..16704)
                     /locus_tag="VQT46_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2370448.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16730..17584)
                     /locus_tag="VQT46_000357"
     CDS             complement(16730..17584)
                     /locus_tag="VQT46_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET2370449.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYLNNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17741..18145)
                     /locus_tag="VQT46_000358"
     CDS             complement(17741..18145)
                     /locus_tag="VQT46_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET2370450.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERRVRI"
     gene            complement(18215..19696)
                     /locus_tag="VQT46_000359"
     CDS             complement(18215..19696)
                     /locus_tag="VQT46_000359"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET2370451.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIVYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSADHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFARVLEDAGVYKQTEQGQTAFMRFVEHVGILLD"
     gene            complement(19715..20893)
                     /locus_tag="VQT46_000360"
     CDS             complement(19715..20893)
                     /locus_tag="VQT46_000360"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET2370452.1"
                     /translation="MAQHLTTEALRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVFENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            21058..22065
                     /gene="galR"
                     /locus_tag="VQT46_000361"
     CDS             21058..22065
                     /gene="galR"
                     /locus_tag="VQT46_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET2370453.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQNLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHDRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(22111..23148)
                     /locus_tag="VQT46_000362"
     CDS             complement(22111..23148)
                     /locus_tag="VQT46_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2370454.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAVEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(23149..23502)
                     /locus_tag="VQT46_000363"
     CDS             complement(23149..23502)
                     /locus_tag="VQT46_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET2370455.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23746..24636)
                     /locus_tag="VQT46_000364"
     CDS             complement(23746..24636)
                     /locus_tag="VQT46_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET2370456.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDA
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24769..25305
                     /locus_tag="VQT46_000365"
     CDS             24769..25305
                     /locus_tag="VQT46_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2370457.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNLPTSYLQHLVMSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(25472..26278)
                     /locus_tag="VQT46_000366"
     CDS             complement(25472..26278)
                     /locus_tag="VQT46_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET2370458.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26623..28143)
                     /locus_tag="VQT46_000367"
     CDS             complement(26623..28143)
                     /locus_tag="VQT46_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET2370459.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPNLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLAALIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLVQKEKENLVIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGKTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMEPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(28136..28864)
                     /locus_tag="VQT46_000368"
     CDS             complement(28136..28864)
                     /locus_tag="VQT46_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370460.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKAPATDFVADLFGGSVHD"
     gene            complement(28879..29643)
                     /locus_tag="VQT46_000369"
     CDS             complement(28879..29643)
                     /locus_tag="VQT46_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET2370461.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVVDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHDIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29647..30090)
                     /locus_tag="VQT46_000370"
     CDS             complement(29647..30090)
                     /locus_tag="VQT46_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2370462.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKFQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30772..31068)
                     /locus_tag="VQT46_000371"
     CDS             complement(30772..31068)
                     /locus_tag="VQT46_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2370463.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQT46_000372"
     CDS             complement(31090..32154)
                     /gene="pepA"
                     /locus_tag="VQT46_000372"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET2370464.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            32555..33256
                     /gene="galE"
                     /locus_tag="VQT46_000373"
     CDS             32555..33256
                     /gene="galE"
                     /locus_tag="VQT46_000373"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2370465.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            33679..34638
                     /locus_tag="VQT46_000374"
     CDS             33679..34638
                     /locus_tag="VQT46_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370466.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKEISESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLGFILLLWRGGRKDAD"
     gene            34628..35584
                     /locus_tag="VQT46_000375"
     CDS             34628..35584
                     /locus_tag="VQT46_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET2370467.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLTLQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRSRQ"
     gene            35581..36333
                     /locus_tag="VQT46_000376"
     CDS             35581..36333
                     /locus_tag="VQT46_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370468.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            36429..37394
                     /locus_tag="VQT46_000377"
     CDS             36429..37394
                     /locus_tag="VQT46_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370469.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTKFEDSRHGQEVSFESVKEINPAILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQT46_000378"
     CDS             complement(37619..37861)
                     /gene="yidD"
                     /locus_tag="VQT46_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET2370470.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37861..38583)
                     /locus_tag="VQT46_000379"
     CDS             complement(37861..38583)
                     /locus_tag="VQT46_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2370471.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(38570..39139)
                     /locus_tag="VQT46_000380"
     CDS             complement(38570..39139)
                     /locus_tag="VQT46_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET2370472.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKSQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(39158..39886)
                     /locus_tag="VQT46_000381"
     CDS             complement(39158..39886)
                     /locus_tag="VQT46_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET2370473.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQT46_000382"
     CDS             complement(39886..40626)
                     /gene="xerD"
                     /locus_tag="VQT46_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET2370474.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGEKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40617..41078)
                     /locus_tag="VQT46_000383"
     CDS             complement(40617..41078)
                     /locus_tag="VQT46_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2370475.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(41075..41596)
                     /locus_tag="VQT46_000384"
     CDS             complement(41075..41596)
                     /locus_tag="VQT46_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET2370476.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(41572..42543)
                     /locus_tag="VQT46_000385"
     CDS             complement(41572..42543)
                     /locus_tag="VQT46_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET2370477.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYKTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGKSSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQT46_000386"
     CDS             complement(42540..43334)
                     /gene="racE"
                     /locus_tag="VQT46_000386"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET2370478.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIYVEHVEL"
     gene            complement(43541..43789)
                     /locus_tag="VQT46_000387"
     CDS             complement(43541..43789)
                     /locus_tag="VQT46_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET2370479.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQT46_000388"
     CDS             complement(43931..45556)
                     /gene="treC"
                     /locus_tag="VQT46_000388"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET2370480.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTGNGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKDINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQT46_000389"
     CDS             complement(45734..47701)
                     /gene="treP"
                     /locus_tag="VQT46_000389"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET2370481.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGNDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47886..48596
                     /gene="treR"
                     /locus_tag="VQT46_000390"
     CDS             47886..48596
                     /gene="treR"
                     /locus_tag="VQT46_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET2370482.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            complement(48629..49432)
                     /locus_tag="VQT46_000391"
     CDS             complement(48629..49432)
                     /locus_tag="VQT46_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2370483.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFISVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKHLSVRKRAKDIARVFQDPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKLKLLLLDEHTAALDPKTSQMVMDLTQKIVEYHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(49445..49873)
                     /locus_tag="VQT46_000392"
     CDS             complement(49445..49873)
                     /locus_tag="VQT46_000392"
                     /inference="COORDINATES: protein motif:HMM:NF014684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370484.1"
                     /translation="MKTEIGLVLRSTGDNIPMSEANGVNVNTMKIVGYMISTGLIALC
                     GSLFAQNDGFSDVTSGTGTIVVGLSSEVLIHDLTIGGRLLSIGIGAIVYRLIILNIYE
                     IPNLDQNLVRLFNAILLALVLFAPALQKRLKIRGLKLRNE"
     gene            complement(49882..50322)
                     /locus_tag="VQT46_000393"
     CDS             complement(49882..50322)
                     /locus_tag="VQT46_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370485.1"
                     /translation="MNFVLSSLSEGLLWSIMAIGVYLTFRILDIADMTAEGAFPMGAA
                     IVVSQIQAGANPWLATLLALLAGMVAGLISGMLHTKMKIPALLTGIVTLTGLYSINIK
                     IMGSVPNLSLGDSATVFKQLASLGLTNEGAVFSLSLVCLLLVWF"
     gene            complement(50367..51272)
                     /locus_tag="VQT46_000394"
                     /pseudo
     CDS             complement(50367..51272)
                     /locus_tag="VQT46_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512061.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
BASE COUNT        15175 a        11736 c         9477 g        15288 t
ORIGIN      
        1 attaaaaggt taagtaattt ttccaaaata cagcactcat atagacagta tcatcaatta
       61 tagccattgg gattttttga ttgccaattc catgtatctc tacacatgtc ttcaatcgat
      121 tttgttgtcc tccaatttaa ttccttatat gctttgtctg catttgcata ataagttgca
      181 acgtctcctg aacgtcttgg aactatttta taaggaatag ggatcttatt aacactttca
      241 aatgtattta caagttgtaa tacactagtg ccttctcccg agcctaggtt atagatataa
      301 acatctgttt tttcagatac tttttctaaa gcttttatat gtcctattgc taaatctact
      361 acttgaatct tttatctcat ttttcccttt ttcaaataag ttatctactc tatgatcagt
      421 tatttccatt tcgtttacta acatgacgca gtcacctagc atcatatact ccaacttttt
      481 ttctgaaagt ttagcaaata ttggtaagcg ataatatagt atattgaaac tagaatagta
      541 cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgattg atttgtccta
      601 ttattatttc attttactat actctgttaa ttcatatgag tttaaaccga tttcatcttt
      661 aacctcgagt aaagcagttt caaatatttg tttaagagtt tttgattctt tacaattaac
      721 cgacaaactt tctgataaaa tatgtacaac ttctgagact gaataaccta tctcctcttt
      781 agaattatat aaatctgtag ctccaccaat aatccaaaaa tactgatttt gtgaacctac
      841 aatatcctca ttttctacgg aacttccttg tatcgaacaa attttattta tctttaccat
      901 aatacttcaa cccttttagt gtcaaaagta aaccaattcc tgtcactgtt aagaatagtt
      961 ccataatctt gttcgaacca gtctttggta atttttgttt tacatctact atttctttag
     1021 atttattaat atgattttca gtttctctgc catctccaac tattttatag tttacttctt
     1081 ctgtcttatt atcttgttta ttgtcgatct tgtcattcat ttgtctatta tctttacttg
     1141 agttaaactc tccgttcttc tggttactat caattacatt atttgaatta gattgttttt
     1201 cctctttgtt tttttctttt tcgtttttat cacttaaatt atttgttaca attttgtaaa
     1261 gcccattctc cgttacaata ttgaaattac catcgctatc acgtataaca gattctttcc
     1321 catttgcatt agatttgatg aatgatatat acttaccgga taaattataa aattggttat
     1381 ttaaaacggt tattttaccc tttgaatcct caataacaat tccttcttta ccaccgaata
     1441 tactattctc tgagactact aaattatcac taactcgtaa taattcaata tttggttgtt
     1501 ctgtttcctt agaattatta ttaattacat tttttgttac agtaatatct gatacttttc
     1561 ctaaatattc tgcactatct tttgcaactc gtatcgcttt tgttttagga tcggcaatat
     1621 taaatatatt ttcggcgata accacctgtt tatttaaatc taataggtct ttagtgtttt
     1681 tatagctata agcatttact aaagctgctc cgctttctcg ataatgtaca ctctctcctt
     1741 taactttctt atcaaagcga tttcctttga ttaatacatc agtgaatcct gtaaaacgta
     1801 cacctgcata catcatgtta tcaaaatgat tatttaaaat tttaatatta gaggggttct
     1861 gtgtcgacaa tgtttgatag tgtgtgccaa ttgctgttac taattcccca gatttatcac
     1921 ttttgccaaa ataggaattt tgaatagtca cattttcaga ttttttccca tcatcattca
     1981 aggcataagg aaaacctttt ctagttaatg gttcaatctg aatgctctcc ttacttatga
     2041 tttgcccatc cttcatcgtt ttgggtaagg cttgcccaag aaaacgagaa ttatcaacta
     2101 atacattttt cgaacctgca atttgaatag catgcccttg ataactatcc ttgaatgtta
     2161 cattttttat agttacgtta tttgaattcc caatagcaaa tgcacctgaa gaatttataa
     2221 gtggtagatt ttttgcttta gttccttctt cattcaaagc accgttcata tcaatcgtac
     2281 caccagaata actaatatct tctgttgggc cccattctac ttgcgcacca tcatccgtaa
     2341 ataaacctgt cataaaaaca atggaagggt gattcttaat atttatacca tttagaattg
     2401 tagctttctc attcaattct aagtgtgtat gactttttaa aaaaacaatt tcttttacta
     2461 aataagttcc ttcaggaaaa tatacatttc ctccacctag cccttgagct gcagcatcta
     2521 ttgcatcttg aattgcttgt cgatcatcat gaatcccatc acctaccgca ccataatctt
     2581 ttacacttaa agcagtatct tcaaattctt ttttgataat tctgtcactt ataacatctt
     2641 ccttataact cttattttca ttagtagata ttactgtaga ttcaactgtt ctgttgtcta
     2701 attgtgaatt ggaacgaata gtaccattag agctgatact attaacactt aacgaattat
     2761 ctaaaccatt agtggttgaa ttagaggcaa tcatttcagc agaacgattt tgattaacag
     2821 ttggtgaatt atctaaatca ttagtgattg cattagaaga ctcttttgta gccatcggtg
     2881 aagaactagt aacaacttca tccgataaaa taccttggct tcccaaaatt gaaattgcca
     2941 atagtaccga gcaagtcccc acctttaatt tacgaatact gaatacctca ttaggaacaa
     3001 aatatttcat cagaacctcc aattttttta ctatttttaa caattgatta ttacttttct
     3061 taaaatagat agaatgacac cgctgtcatt atctttatca tatattttcc aaattgaatt
     3121 gtcaaggaat aacacaagaa aatattaaaa tttatactct tcggaaatct cttcaaacta
     3181 ggtcagtgcc gccttgccct aagtctaggt tactgacttg gtcagttcta tagtagactg
     3241 aaactataat agtacacctc tacttctaaa acattgttag aaatcgattt gactgtcccg
     3301 atcgatttgt cctattctta tttcatttta ttatatctac aacctcaaag cagggttttg
     3361 agctatctat ggccaacttc ctagtttgct ctttagcctt ccattcaaaa gtgatgctat
     3421 ctttcttagc ttgaatataa aatatcccat ttactatatt taaatttgtt gatatgttgt
     3481 aaattataaa tgaaagaaca aatatcttgt catacaagca ttcgccaggg atatttacat
     3541 gaatatcgct catatggcgg attgaaacta aaacactaca atatatttct taaatagacc
     3601 ttctataaaa gctagattta acctcgataa aaatagatgc agtgcttcta aaatactgga
     3661 atagggcata taggtaatcg tagacaagtg ttttatagat tgtctcgcgg gagatctaat
     3721 gatgtatagc aagcatcact aaacatatag aatatttgtg ttattataat gtcaatatgc
     3781 tataaattct atcatgcaaa agaatgacta gaacatgaaa gacaggcaca aaactttgaa
     3841 caatattctg aaaacaaaaa aagacgcgag tttccacaat ctcactcatg gaaactcacg
     3901 tctttcaaaa aatagggtga attaaaaact agaacaagac actagatttt ctaaatgatg
     3961 tctagtaagg attctaaatg ctacaccaaa ttgctcacat cttatttcaa accacgggac
     4021 tcccacaaga aaggaaaatc ctataaaaat tctctctctg aggagagaga ggcctcaact
     4081 acaggtgtaa actattatca attgaaaaca acagttttta cactcaatta gactttttag
     4141 ggacaggatc actttcgctt gactgtagtt tgtcattttt ttgataaagt tagcactttt
     4201 tcagaaactg ttttgaaagt ctcaatgata tagtctactt cttcatcgct taatttagta
     4261 tgaagaggga gggtaatttc attctcaaag aaggcatagg ccttaggata gttcgtcata
     4321 tcaaatccaa gattcttata ggctgtcaag agaggaagcg gtttgtagtg aacattactt
     4381 gcaattcctg ctttagccaa ttcttggatg atgaggttgc gttcttctag gcttgctcct
     4441 tctacacggg tgatgtagag gtggcgtgaa gattcgacag tttcagtctt gtgtgccaaa
     4501 ggatggatgc gagaacctgc aaaaccacta tcatagcggt ccacaatgtc cttacggcgt
     4561 tgcaacaaac ttggatagcg gtccaattgt accaaaccaa gtgaagccat gatatcggtc
     4621 atgttgcact tataggctgg tgtaacgata tcgtattccc atgaccccag ttgcatcttg
     4681 gcaagagcat ccttagtttg cccgtgaagg gaaaggattt ggaattcctt gtacatctct
     4741 tcgtcatcaa tcactggatt ggctttccaa gtcgcacttc caccttctgc cgttgtaaag
     4801 ttcttaacgg catggaatga gaaggaagta aagtcagcga tagaaccaga aggttgtcct
     4861 ttataagtag atcccaaagc gtgggcacta tcagagacaa tgacaatacg gttaaaggcc
     4921 ttttgccact tgcttgaagc ggtaaagaag tcacgttttt tctccacgac ttggaacaaa
     4981 cggtcataat cgcaaacaat ccctgcgagc tctactggga taatcacctt agttttctca
     5041 gtgatagctt gctcaagcag gtcatagtcc atctcaaacg tatctgcttg gatatccacc
     5101 atgacagggg ttgctcccac gtgcgtaatg acactacatg aagccgtata ggttatggct
     5161 ggaacgatga cttcatcacc aggtcccact tcaaaaacgc gtaaaatcaa ctccagagcg
     5221 gctgtcgcag agttgagaca aacagtctta ggtgtctgtg tgtaaagaga caagcggcgc
     5281 tccagttctt ttgttttagg acctgttgtg atccaaccag aacgcagggt atccgctact
     5341 tcagcaattt ctgcttctgt gatatcaggc ggtgaaaatg gaatattgta atttggcatt
     5401 gatttgctcc ttttatctgt actcattctc ttatgactac tttattttag taccttaaac
     5461 acggtttgaa acatgatttt gatgtcccca aagaaactaa actctcggag ataggcgagg
     5521 ttatagcgca tcttttcagg aagaacatgc tccacatagg cctgatcaac tgacagacct
     5581 ttctctgtca tttgactgat gatggtgtcc tcatccttgt agttgatgct ggctggagag
     5641 gtaattcctg cttgcaagag caaggttgcc atcatttcag tgctatactg ctctgtataa
     5701 cgtggcactt caggtcgtgt accgacaaag gacatctcac ctttaaggac attgaccaac
     5761 tgaggcagtt cgtccaaacg gacacgtcgg atgaaatttc caaccttggt aatacggcta
     5821 tcgttagcag aagtcaccag atttcctttt ttatccgcat ccgtcaccat ggtacggaac
     5881 ttccaaatct tgaaccgacg gttgtactgg gtcacacgct cttgcttgta aatcactggc
     5941 cccttgctat ccaacttgat ccaaatgctc aagatgagaa agatgggaga ggtcagaacc
     6001 agtaagacca aggccaaaac ccagtccaag caacgcttga aaatcagcga acccttcctt
     6061 ttagagacaa gctggtagta agactcaacc tcgcttgatt tcatttccac aggcaagtct
     6121 tcccatttca gcatgctgtt ctcctttgtt tttattatac tatttgtcaa cactttttgt
     6181 caacactttt cattatacca caaaatggaa aaggcggtga aaaaaatctg taatttgaag
     6241 gatttccttc tagtactcaa tgaaaatcaa agtacagctt tgagattgca gataaagctg
     6301 acatggttta aagagatttt caaagagtat aggccatggc ccctgcctgc aaactataca
     6361 tcttgtgata ggttcctccc agagccaaga gttcctcatg ggttccactc tcgataatgc
     6421 gtcccttatc caagacatag atgcagttgg cgtcttgaat agtagaaagg cggtgagcta
     6481 tagcaatagt tgttcggccc tgtctcatct tcgccagaga agcttgaacc aagctttctg
     6541 tttcagagtc aatattggct gtcgcttcat ccaaaatcag gattttaggc tggctggcga
     6601 ctgttctagc aaaggcaaga agctggcgtt gcccagtaga gaagctcgaa ccacgctcgg
     6661 aaacagggga gtcgtacccc tgaggaagtt cttgaataaa ggaatctgca tccacaaagg
     6721 ctgccgcagc ctgaacctgc tcatcactga tttcttggta catggcgata ttggacttaa
     6781 tagttccatg atagaggaag ggttcctgca agaccaaacc gatgtttttt ctcagctctt
     6841 cttgactgaa atccctgata tccacatcat ccaagagaac tctccctgac tggaattcat
     6901 aaaagcgcat gaggacattg ataatagacg atttccctga acctgtatga cctacaaagg
     6961 caatggtttc acccttatta acagagaaag aaatgtcatc cagaatcgga tgtttaccgt
     7021 catatgagaa acacacatgt tcaaagcgga tattgccttc ttggactttg gcttgcccat
     7081 tttcttgaag aggttcatag gtcctctcgt ctaccagggc aaagacacga cctgcagaaa
     7141 ccatagacgt ttgcagtgtt gaaaagtttt gcgtcacctc aatcaaaggg tcaaagaggc
     7201 ggttgatgta ctggataaaa gcatacatgg tcccggccgt tatcccgata gaaagaccac
     7261 gatagccaaa ataggccatc aagacagcat aacctagaag tttcaacaaa ctcatggcag
     7321 gtctcaaaaa gagggcatcc aaggctacag aacggttggc atagaccaag tgctcttggt
     7381 tgatttcatc aaattctgcc tgcaggcgct tctcttgatt aaaggcctgg attattctga
     7441 ttccctcgat gttttcagcc agcttgctat tgatatctga caagagactt ctggttttct
     7501 caatgatttt cactgatttt ttccgataga gattgaccaa aaggaaaatc aaggggagaa
     7561 agagcaagac taatgctgtc aaacgaaaat ccaataccaa catggtataa agggttgtca
     7621 gaaagatgaa aactgctgag ataaagctag ataaaatccc agaaaacata tcactaatcg
     7681 tctcggtatc gttggtcaaa cgagaaacga tagaacctgc tggcgtcttg tcaaagtaag
     7741 acatgcccag tttctccata ttggcaaagg catcccgacg aatatcccta acaatactgt
     7801 aagacacgcg cgcaaagaga agattgccga catactgaac tacagtttgt aggatgtaga
     7861 gaccatagta gaccagcaaa acggtaacgg ctagttggtt aagattgctg agatactggt
     7921 cgataaagtg ggaagccacg aggggtatga cacttttaat gaccgtcgtc gctaggagaa
     7981 aactgagtgc caaaaaggtc aggagtctat aaggcttgag ataagacatc aagcgcttca
     8041 atacagccca ttgttcttgt ttattctgca tcttcttctc ctttcatttc taactgctga
     8101 gactggtagg tttgggcata ccagccatcc atcgctagca agtcttcgtg cctgcctcgt
     8161 tcgataattt gaccattttg tagaactaaa ataaaatctg catggacaac agcactgagg
     8221 cgatgggcag ttataatggt tgtcttgtcc tttcgcgtct ccttgagatt gtcgataatc
     8281 gcatactctg tcttggcatc tacggcggat aaggaatcat ccaaaatcaa gatatcaggg
     8341 tttaaaatca tagcccgact catagccaac cgttgctttt gaccaccaga aagactgact
     8401 cctttttcac caatcagcgt atcaaatcct tgaggcatgt ctacaatatc ttggtaaact
     8461 cgggctagct tagtagcttc ctcaacctct gaaaggggca agttaggatt gccaaagcgg
     8521 atattgtcta ggattgaagt cgcaaagaga aactggtcct gaggaacata gcccatgaga
     8581 ctgcgaagtt ctgtcaaacg atagtcccga atatcgtgac cgtttagata aatggcaccc
     8641 ttatccacat cgtattcacg caagaggagc ttgattaagg acgttttccc agagcctgtc
     8701 tgcccaacca agcccagtgt ttgccctttt gccaaactaa agtgaatatc cgtcagtgtt
     8761 tcctcatttt caaaagcaaa gctgtcaatg gcatactcca aacgcccatt ttcaatacca
     8821 tccagaggaa actcagggtc ttgtacagga gattcctgag acaaaagatt ttcaatccgc
     8881 tggtaagaaa ccttccctcg ctgagtagta ttaaagagga agccgatggc cataagaggc
     8941 cagaccagca tatccaaata gctgataaag gtgactagat taccaactgt aatctgccct
     9001 tcctgaacca tcaaggagcc aaccaaaagc gttaaaacat aggacgaacc aacaaacaag
     9061 agaaccatag ggtcaaagag actatcatat ttcatggttt gcaggttctt ttggaaggtt
     9121 aattcattga ctgcctgaaa agacttcaac tcgtctgcct gataaccgaa agacttggtc
     9181 actttgatac ctgatacgga ctcctgtacc ttgttattga gttcagaaaa agcagcttgg
     9241 gattcgccaa aggccttatg agtctttctc cctaggcgac tagtcgcata ggccatgaaa
     9301 ggtaggggga gaatggcaac aagagtcatc tgccatgaga tgctaaagag catggtcaac
     9361 aaagtcacca gagccgtgat agaggcatcc accgcagaca tgacaccgcc acctgctaaa
     9421 cgagtcaagg cattgatatc attggttgcg tgtgccatca gatcacccgt ccgataggtt
     9481 tgataaaagg ctggcgacat ttttgtgaaa tgcttaaaca agcgagaccg catgatctgt
     9541 cccaagcaat aagaggtccc aaggatatac atacgccaca catagcgcaa atagtacata
     9601 ccaaaggctg caagtagcaa gtaaaatagg ctaagaagga ggtcctgctg ggttaattgc
     9661 cccgatgtga tggcatcaat gactcgcccc ataaccatag gaggaatgag attgagaacg
     9721 gaaaccaaga ccagggccac aatcccgact agataacggt gtttttctaa cttgaaaaac
     9781 caccagagtt tttgaataat ggacataaaa tccctttctg attgcaaatg gaaacctgag
     9841 gccaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc tgctcaaagc
     9901 actgctttga ggttgtagat agaactgacg aagtcagtaa cctacatacg gcaaggcgac
     9961 gttgacgcgg tttgaagaga ttttcgaaga gtacaagacc ccaggttttt cttattcata
    10021 agttacgact gtaacagcac ccttgtcata ttcagcaata aagatattgg ctacattgtc
    10081 atgcccttgt ttgctgaggt tatcaagcaa ccactcttcg ctacgaccaa tcgattccaa
    10141 gacgtctact tgaatcacac cgtcagtcac aactggatac ttaggatttt catctcccat
    10201 ttgcacaacg atgagttgcc cattttgctc ttgcacagct cgtttgactt gcttcatctg
    10261 gaaaatccct tggctacgaa gtttgagggc tacatccgat gcagacaaac caactgaacg
    10321 acaggcttat gggtcaatat tcccattttt gataaggaga gttggcttac catcaatcaa
    10381 acgtttcaca aagtgaacat tgttgttgag ctatttgaga gtcaagatca gtttgattaa
    10441 aatttcgata taattaagtg tcatttgttc acatccacca gttcaattgc gtctgtctta
    10501 tacaattcga ctttctctaa caggtacttg tctggctcac ttccgtttag ggcacgataa
    10561 tagcgatctc ccaccttgat aagtgcgcca tctgtgtttg tggaagtatt aacatggact
    10621 tctgacttgt ctactcccaa atctttggaa acaacctcga tgaaatgaag tgaagtttga
    10681 aatttattgt tagaaacttg attgttttga taagtcgtga tgctgaccaa aagcatagct
    10741 aaataaggcc agagctgaaa tcatgaccaa ctcacgaaat ttggttcctt ttttatcatg
    10801 gtatgccttg aaagcaaaaa aaactgtcac agctaataga acaatcccaa agccaaccat
    10861 gataccattt tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta
    10921 ttttcactcc ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa
    10981 ccatacgttg gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa
    11041 aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg ccctaactag
    11101 tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg ctgaaaatgc
    11161 tgatatcatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa agaaacacgt
    11221 ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgctctt cccaagagcc
    11281 tgcccgtaaa ggctatgctg gaaccatgtt cctttataag aaagaactta cacccactat
    11341 cagcttccca gaaatcggtg ccccttctac catggacttg gaaggccgta tcatcactct
    11401 agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg acggtctcaa
    11461 acgcttggaa gaacgccaag tctgggatgt caaatatgcg gagtatttgg ctgaactaga
    11521 caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg aaatcgacct
    11581 tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac gtgctggatt
    11641 taccaaccta ttggcaactg gatttactga taccttccgc catgttcatg gcgatgttcc
    11701 tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca atacaggctg
    11761 gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta aatctgatat
    11821 gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg acttgtaagg
    11881 attttctata tggactacaa tgcggtcatt cccgagtttc ttgtatcgaa tatcgaacag
    11941 tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg ttcagaagaa
    12001 aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca aaggatcaac
    12061 tagctgaact gacctacccc tttggtcgtg gagtcaatct ctcctttggc ataaaggatg
    12121 ttccaaaact ctatcaaaaa gtgatggagg caaactatcc tatttatcgt cccttgacca
    12181 aaagaaagtt tcgtgtcagt gatccctata tctatcctca taaatttgca gttttggatc
    12241 cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa aagtctttaa
    12301 aagttagaaa aaggcatatt gtcaggtgtc taaaaacttg atagtatgcc ttttatgatg
    12361 gaaaaatctt ctaatactct tcgaaaatct cttcaagcca cgtcaacgtc gccttaccgt
    12421 aggtatataa tactgactct gtcaattcta tccacaacct caaaacagtg ttttgaggtt
    12481 gtggatagct tcctagtttg ctctttgatt ttcatttagt ataaatgtta gcttacaatg
    12541 gagtttttgt tcaccctctc ttctgtttgt tcgtttttta aaccaaaaca ctaacaaaat
    12601 agttgatttc taaagttatt tagtgtaaaa taaaaacatt ggctcaagcc tatttaaaat
    12661 tgaatatcgt tttacttgtt tatgtcgtga attggcacga cgtttctaca aggtgccgga
    12721 acacctaaca ataagtaagt cagcagtgag atatggccgt ttttgccatg cctatttggg
    12781 ggacttactt agagattaag taggtctttt ttgaatattt ttaatatttc ccttaattag
    12841 tgcggacggg aggtgaaatt atcctgtgaa taatttcagg aatccaggga atttcatccc
    12901 taatttttga gcccctagct ctttcatttc taggcttagg ctaaaatagt tccccgaact
    12961 attttactct caaaaatccc gtcatagaca ataacaagat tattgtctat gataccacta
    13021 caacgggaaa tatttgataa gactcgcttc gctcgtaata gttttatcaa atatatagca
    13081 ttagcaaaag ggatcactat agaaacattt aaacaacaag taaattaact tttagacttt
    13141 aggaggtctt atgaaattat tagaagagcg catcctcaag gatgggcata tcttgggtga
    13201 taacatcctc aaggtagatt cctttttaac ccaccaagtt gactttagct tgatgcgaga
    13261 gattggtaag gtttttgcgg aaaaatttgc tgctgccggc attaccaagg tcgtaaccat
    13321 tgaagcgtcg ggtattgccc cagccgtttt tacagctgaa gccttaaacg ttcccatgat
    13381 tttcgccaaa aaagctaaga acatcaccat gaacgaaggc atcttaactg ctcaagtcta
    13441 ctcctttacc aagcaggtga ccagcaccgt ttctatcgct ggaaaattcc tctcaccaga
    13501 ggacaaggtt ttgattatcg acgatttcct tgctaatggc caagctgcta aaggcttgat
    13561 tcaaatcatc gaacaggccg gtgccacagt ccaagctatc ggtatcgtga ttgagaaatc
    13621 cttccaagat ggccgtgatt tgcttgaaaa agcaggctac cctgtcctat cacttgctcg
    13681 tttggatcgt tttgaaaatg gtcaggtcgt atttaaggag gcagatctct aatgcaaact
    13741 caagaaaaac actcgcaagc agccgttctt ggcttgcagc acttactagc catgtactca
    13801 ggatctatcc tggttcccat catgattgcg acagcccttg gctattcagc tgagcagttg
    13861 acctacctga tttctacaga tatcttcatg tgtggggtgg caaccttcct ccaactccaa
    13921 ctcaacaaat actttgggat tggactccca gtcgttcttg gagttgcatt ccagtcggtc
    13981 gctcccttga ttatgattgg gcaaagccat ggtagtggcg ctatgtttgg tgcccttatc
    14041 gcatctggga tttacgtggt tcttgtttca ggcatcttct caaaagtggc caatctcttc
    14101 ccctctatcg taacaggatc tgttattacc acgattggtt taaccttgat ccctgtcgct
    14161 attggaaata tgggaaataa cgttccagag ccaactggtc aaagtctctt gctttcagct
    14221 attactgttc tgattatcct cttgatcaac atctttacca aaggatttat caagtctatc
    14281 tctattttga ttggtctggt tgttggaact gccattgctg ctactatggg cttggtggac
    14341 ttctctcctg ttgcggtagc tccacttgtc catgtcccaa ctccactcta ctttgggatg
    14401 ccaacctttg aaatctcatc tattgtcatg atgtgtatca tcgcaacggt gtctatggtt
    14461 gagtcaactg gtgtttatct agccttgtct gatatcacaa aagatccaat cgacagcacg
    14521 cgccttcgca acggttaccg cgcagaaggt ttggccgtac ttctcggagg aatctttaac
    14581 accttccctt acaccggatt ttcacaaaac gttggtttgg ttaaattgtc aggcatcaaa
    14641 aaacgcctgc caatctacta cgcagctggt ttcctggttc tccttggact gcttcctaag
    14701 tttggtgccc ttgcccaaat cattccaagc tccgtcctcg gcggtgccat gctggtgatg
    14761 tttggttttg tatctattca agggatgcaa atcctagccc gagttgactt tgctaacaat
    14821 gaacacaact tccttatcgc agctgtttca atcgctgcag gtgtcggtct caacaacagt
    14881 aatctctttg tcagcatgcc gacagccttc caaatgttct tctcaaacgg aatcgtcgta
    14941 gccagcctac tcgccattgt cctcaatgcc gtattaaatc ataaaaagaa ataagaaaaa
    15001 gaggtgcgag cctctttttt gtttatcaca aattgattat aaatacaatc aatcccaatt
    15061 cccatctaat tgaattggac ctatttcaaa ttctttaaaa tattatgttc caaatcgtta
    15121 atattatata agaatggtaa aatatcaaat gtttctcgta aattattctt agccttatac
    15181 caaccttgtc catcagtaat ccacataaac tcaacattag gaatagcttt aatttcttca
    15241 gcaatcattt tgtaagatct agccgtctca tttaattttg aaccacttcc tgaataaaaa
    15301 ttaacctcaa tcagataaag cacttgttca ttttttatga caaaatcaaa acgtttcaca
    15361 gtattcccat cattcgtaat agcagataaa tcgacagaaa aaatttcctc tatttcattt
    15421 tgttcaatct ctttaaataa attctctcct aaaatatacc cttcagcttc aagataactt
    15481 tgaacaatat tttccatcgc atctccagtc cgatttttgc gcccattagt atccatacca
    15541 acctcaacac ctgtaacgta gtcaactaaa tttgatacta aatgattttg caataaatca
    15601 aatatacctg atttttccaa aaacatagta tattcttcaa tactatagtt tcgtttacta
    15661 aaatcaaaat agaaatcttt tatcggatcc ttaacaataa tcgtatctct caaacgttta
    15721 gcaataagta gaggcacaac tttcaaaatt tctggataat tttgatataa gtctaaaaaa
    15781 tcctcttgta tatttttact accaataaga ctattcataa tatttagagc aacttttata
    15841 ctagatacat ttttataaac cttgggaaaa tctgtataat aagtccagtc agctactgtg
    15901 tcggtcatcg ttgacaacca ctcatcaaaa tttctagttt gtttcatttt ctgcctccaa
    15961 cctcttcctt gcaattttta aatattcttt ttcagcatcg atacctataa atcttctacc
    16021 taaccgcttc gcaacaacac ccgtagtgcc actaccaaca aatgggtcta gaatatagtc
    16081 accctcttta gtagaggcta aaataatgcg ttctaacaaa tactctggtt tttgagttgg
    16141 atgtttccca gcccattttt caactttctt tgttaaagaa cccgtccaga catctttcat
    16201 ttgttttcca tcattcaatt ctttcattaa atcataattg tagtaatgac gagctttttt
    16261 atcatttttt ctggcccata aaatggtttc agtagaatgg gtaaaataac gacaagataa
    16321 attgggggca gggtttgttt tctgccaagt aatattattc agaattttaa aaccttcttg
    16381 ttctaatgcc attccaactg agtatatgtt gtgcaaacta cctgaaatcc ataccgtccc
    16441 attaggcttc agaacttctt ttgctaggcg aatccattta cgattaaact catgtttttc
    16501 ttcgaatgaa gaaattttat cccaatctcc tttatcaaca gaaacaactt gtcccccaga
    16561 attagatatt ccaccattac ttaaaaaata aggtggatca gcaaaaatca tatccatact
    16621 ttctggtttc atttttgata agaacttgaa cgtatctgaa tgaacaagaa tcatcttatt
    16681 tttattgtag tatggttttg tcataagaac acctccatac ttatattcgt tatttttcat
    16741 aatttgtgac tataatttca gaaatttttc ctcgacttga agattttgct ccattagttc
    16801 gggtagcttc aacataatgt atattaaaat ccttatacaa ctcctctact aaagcactag
    16861 aagaatttga taacataaca taagctcctg tatcactcaa tctcttaaag gcatctctta
    16921 atcttacttg atctgcaaaa gagaatccct catgagtata agacgtaaat gcactcgtct
    16981 cagacaatgg aatatatgga gggtcaaaat acacaaaatc tcctgttcga acatctacaa
    17041 ttgccttttc aaaatctccc actttaattt ctagttgatt gttatttaga taaactgaaa
    17101 tagcagatat caattcctca tcaacaattt taggattctt ataacgtcca tatggaacat
    17161 taaattggtt cttagaattc acacgatata gaccattaaa gttcactctc aacatatata
    17221 gaatacgtgc agctctttgt acttcggaca tcatatctat tctttcatca cgatctgcag
    17281 aacgtaaatc taaataatat tcttttgaat tatattcctg atgaactttc aaaatttcaa
    17341 tcaattcttg aggattgtcc ttaatttgtt gatagcaatt tattagttca gcgttaaaat
    17401 cattaataac tgcatcttta ggagccaaat caaaaaataa agctccacct ccaacaaaag
    17461 gttcgaaata cctgttatag gttttaggca ttaattctct aataacaggc aataattgtc
    17521 ttttaccacc tgtccatttc gtgaacggtt gtaaagtaac tttctttatt tcttttatct
    17581 tcatgctttt aattatacca tagaaattaa aacacaactc ttgtattttc taccacatta
    17641 ctaaattttc tattttagaa ttaaatcata tcaatataaa aaaatgagta aggcaaatct
    17701 tataaattcc aaaattcacc tcactctatt aaattactct ttatatcctt acccgtcttt
    17761 cctcagacct ttggcctgtg acaaacatag taaaggttgc tttgcagaca tttctgccct
    17821 cttgattggt gatatccaca tccatcacac aggttgtacg accttgatgg acacattctc
    17881 ctttaatggt caatacatcg tcgagttttc ctgccttaag gtagttgata gaggattgga
    17941 gtgtcacccc atcaagtccc agcgagataa ccaccaaacc actgatttgg tcacatagtg
    18001 tgaatagata gccaccatgg gcattgccat agtagttgag cgacgagttc actactttgg
    18061 tcgtcaccac aacgtgacca tctctcattt tttcaatttc gtaattttca aaggcagata
    18121 tagcgtcaaa atgaaagtct ttcatcgttt cctcctgata tttcaaatga cactatgata
    18181 ctacttttta taggactgtg caaggagaaa gctcctagtc tagtaaaatt ccgacatgtt
    18241 ccacaaagcg cataaaggct gtctgccctt gttctgtctg cttgtagact cctgcatcct
    18301 caagtacacg cgcaaagata gcacccacag agtccttgac gattgcaagg gctttttctt
    18361 tatccgttag gtctggatgt tgggatttga gttggtctgc ccactcctga tgataatcgg
    18421 caactgtaac agcttctcct acaagatagc tagcgacttg ctctacttct tctttcagac
    18481 gtggtggcaa gattgccaag cccatgacct caatcaagcc gatattttcc ttcttgatat
    18541 gttggacatc cttgtgggga tgatagatgc catcaggatg atctgctgaa gtctgattgt
    18601 ctcgcaagac caagtccaac tcaaactgtc catcacgctt acgcgctatt ggtgtgatgg
    18661 tgtgatgcgg tgtcccgtct gtctctgcta aaatctgcac actagaatct gaatactgac
    18721 gccattcctg gaaaatctta tcagctaagt taatcaaatc ctctttggaa tccgaagtca
    18781 agcgtaggac agacattggc cacttgataa ttccagcctt gacctgctca aaaccagcaa
    18841 atcggaaggt cttttgcaag ggagccaatt ccataggaaa tacgtgacgg cctccctgat
    18901 aatgatcatg agttagaata gagcccccca caatcggcag gtcggcatta gatccagcaa
    18961 aatatcctgg aaactgctct acgatagcca acagacgttc aaaactctga cgactaatgg
    19021 ccatgggacg atgctggcca tctaaaaaga tacaatgctc attaaagtaa gcatagggcg
    19081 aatactggaa accccattcc tgaccaacca tttcaaaacg gataatccgg tggttgctgc
    19141 gagctgggtg gttgacccga ccatggtaac cctcattctc taaacaaagt tgacactgag
    19201 gataattact agcttgcacc aacttggcta ccgcaatctc tttcggatcc ttttcaggct
    19261 tagagagatt gatggtaatt tcaagttctc cataatcaga tggaacacga taaacgatat
    19321 ttttagcaat ggccttgagt ttgatgtagt catttttctg actgagttga taaaaatcct
    19381 ctatcgcttg ctcaggagag taggcatagg cttcccagaa gtcacgattg acctgactcg
    19441 gacaaggagt caccaagtcc atcaattcag taccaaggat ttcacgcgca gtctgactat
    19501 cctcaatcgt ctctaatcga acggcttcct caactagctg gtccttgagg tcaatcaatt
    19561 tatccagatt ggtctcaact tccaaaacac cttctcccac tcgtgccaaa acacgattgg
    19621 tcaggtagat tcgatccatt tcctcaaatg aactttcaga aatgacatgt gttacaaatt
    19681 tatctactaa ggtcactata gagcctcctt ttgactagtc aaggacgcga gtgccacctg
    19741 caacttcagc gatatagaag cttggagcgt atccaactac ttcctcgtag tgtttgccta
    19801 cagcttcctt aaaggcctca acagtatctt tttgaaccaa ggcaatggca cagccaccaa
    19861 aaccagcccc tgtcatacga gcaccgagaa ctccttcttg tgcccaagct gtgtgaacaa
    19921 gagtatccaa ttccaaacca gttacttcat aatcatgctc cagagaaacg tgtgacgcat
    19981 tcatcaaacg accaaatgtt tccaaatcac ctgcttgaag ggctgcttga gctttaaggg
    20041 tacgttggtt ttcaaacaca gcatggcgag cacgtttcaa acgattttca tctttaatca
    20101 gatagctata ttggtcaacg gcccactcgt ccaattcacc cagggtctga atatccaagg
    20161 caacttgcaa ttcttccact gctttttcac actcagcacg acgttcattg tatttagagt
    20221 ccgccaattc acggcgtttg ttggtgttca tgataacaac gacattgtcc ttcaaatcaa
    20281 gtggcaccaa gtcgtattct aaagtattgg tatctaagta aatagcacgt tggtcagccc
    20341 ccataccaat agcaaattgg tccatgatac cagagttgac tccgataaag ttattttctg
    20401 tttgttttcc gattttaacc aaatcgagac gctctagttt taaatcaaag agatgctctg
    20461 ccacgactcc tgtcaagagc tccaaggatg ctgaagaaga caaaccagca ccatttggga
    20521 tattcccata aacataaaaa tcaaaacctt tgtcaatcac gtgcccagct tcttgcaaga
    20581 aatgaaggac accttttgga taattggtcc agttgtgctc tttttcaaac ttgaggtcag
    20641 cgagaggcac ttcgataatg cccttgtcct caaagttagc tgagtagaaa cgcaagactt
    20701 ggtcgtcacg cttacgagct gcaccgtaag ttcccaagga aatagcagca ggaaaaacgt
    20761 gcccaccgtt gtagtctgtg tgttcaccaa tcaaattaat gcggcctggt gaaaagaagg
    20821 tttggtctgc ttcttgacca aaaacagcaa gaaagtcttt gcgaagggct tcagtagtaa
    20881 gatgttgtgc catatgaatt ctcctttgac tgtccgttaa gccaccttaa cgtataatcg
    20941 ttttctttct attgtatcca aggaattttc caagatcaat cctttttact aaaattttag
    21001 taaaatatca gtaaaaagaa gaaaaacatg atatactaac ctaatcaagg aggatttatg
    21061 gctaccttaa aagacattgc acagctagcc tctgtctcta tcgcgaccgt atcccgcgtc
    21121 ctcaatcgcg accagagcct atctgttaca gaagaaacca gacaccgtat tttaaccgtt
    21181 gctgaagagc tgggctacac caagcacctc aagacaggcg agtcccacaa acccaagcaa
    21241 aagattgcca ttatccaatg ggtcagcgaa caaggggagc tggacgacct ctactactac
    21301 cagattcgcc taggaataga aaaaagagcc caagagttgg actatgatat cttgcgctat
    21361 tttaatgacc atccttttac cttaagcgag gaagtgattg ggattctctg cattggaaaa
    21421 tttagccgag ctcagatttc tgcctttgaa gaataccaaa aacccctggt ctttctagac
    21481 agtgatacac tttctctggg gcatacttgt attattacgg atttttacac tgccatgaaa
    21541 caggttgtcg attatttcct cagccaagga atggaccgta tcgggattct aacaggcctt
    21601 gaagaaacaa ctgaccaaga agaaatcatt caggataagc ggctggaaaa tttcagaaac
    21661 tacagtcaag caaaaggaat ctatcatgat gaactggtct ttcaaggaaa ctttactgcc
    21721 cagtctggct atgacttgat gaaggaagcc attcagaact tgggagacca actcccacca
    21781 gcatttttcg cagccagcga tagtttagct atcggtgccc ttcgtgccct ccaagaagct
    21841 ggaatcagcc taccagaccg tgtcagcctc atttccttta acgacaccag cctgaccaag
    21901 caggtttatc ctcccctctc cagcatcaca gtttatactg aagaaatggg gcgagcaggt
    21961 atggatattc ttaacaagga agtcctccac gatcgcaaaa ttcctagcct gaccatgctg
    22021 ggaaccagac tgacattaag agaaagtacc ctaaatcaag aataggataa cataaaaaac
    22081 gaatagagtt ctaaaactcc tattcgtttt ttattcgatt acaatcatag acttaatggt
    22141 cttacgttca tccatatctt tgtaggcttg gtcgatatct tccagtttat aacttgaagt
    22201 aaagacgcga cctggattga tatcaccatc aaggacggct tttagtaaaa attgcttatc
    22261 gtatgttgta gcagaagctg ccccacctgc tacagagata ttttgcataa atgtcgaacc
    22321 aagagcacga ttattatagt gtgggactcc tacaaagccc atacgccctc cattatgaag
    22381 aacacctagc gcctgttcta tagcagcctc cgtaccaaca cattcaagtg ctgcgtctgc
    22441 tcctccaccg aggatttcac gcaccttggt aattccttct tgaccacgtt ctgcaacaac
    22501 agctgtcgca cctgactcca tagccatctt ttgacggtct tcatgacggc tcataaggat
    22561 aatttgtgat gctccacgca tcttagccgc gatgacagca cattgaccaa cagccccatc
    22621 accgataaca acaaccttgt cccctttttg aacatttgca acacgcgccg catgatagcc
    22681 tgtcggcatg acatctgcaa gagtcaaaag ggactggagc atcccttctg tatagtcaga
    22741 aggttgacca gggattttaa ccagcgccca gtttgcatag tggaagcgaa tatattctgc
    22801 ctgaaaatca ccccccaaat tattgccaat atgattgtcg caagaaccgt caaatccagc
    22861 aagacaggca tcacactcac cacatccatg tgtaaaaggg acaatcacaa aatcacctgg
    22921 tttcaccgtc gtaatggctt ccacagcttc ttcaacaatc ccaatcgctt cgtgtccact
    22981 atttttgtgt ccagctttcg tttctggatt acggtacctc cataaatctg aaccacaaac
    23041 gcacgcacga accacacgaa taatcacatc atccgcttct attatttgcg gacgttcaat
    23101 gctagcaagt ccaacctgac ctgcctttgt atatactgct gatttcattt aaaattttcc
    23161 ttccttataa agtttaattt tgagatttaa acgatttaaa gctgtctgta gctgagacaa
    23221 gcgctcctct aatttttgct tttcctcttc taaaatacca agcctctcct ctctcgtttc
    23281 atctcccttt tggtagagcg acatatagtc aactaaacta tctacagaga cacccgccga
    23341 acgaaaacac ttaataaatt ccagcgcttc gatatcctga tcttgaaaat cacgaatccc
    23401 agtagcagta cgagtaatcg gtggcacaag accaacccgt tcataatacc gaatcgtatc
    23461 cgctgaaatt cccaacaaat cactggcaga tttaatattc acacgctaac ctcctctcat
    23521 ttcattcact gaattcacgc tattctaact cacttatctt attatataac tttgagttga
    23581 ctccaagtca agcattttgt atctaatcga aaaattttta tcattaacaa tcatatatct
    23641 ggagtttata caatgctctt ctcttaccaa tttttgaaat atttaaataa taaagaaatt
    23701 actctattcc aaataagata gtacccaagt atttttcact tttttctaat gttgatgctc
    23761 ataactccgt tccaagtcac acacctttcg cttatgggtt tggtgagttt ctaggtcagc
    23821 atcaatttca atggtaatat tttgaaaacc acaatctttt aggaaaattc gaatagactc
    23881 tttacaagtt tccatatgtt ccatttcttt tagacaaaca tggacaatgg catttttttc
    23941 caaagcatcc atagtccaga gattaagctg attaaggctg gccacattgt ccaatcgctc
    24001 caggccactc tttacttgct tgatatcaag accttctggc acagcatcca agaaaatctt
    24061 gagtgtagac caaaaacgtg gaagggcttt tgaaagaata aagaaagaaa tgacaaggga
    24121 caaaagagga tctaggatat accagtccgt aaatcgaaga acaatcgcca tcaggataac
    24181 agctacccac cctagcgtat cttccagaaa atgcagactc agaatagact cattctttgt
    24241 ctttccctta ccaaccacca gactcgctaa cagattgata gtaatcgcaa taattcctaa
    24301 ccagagaatc ccctcatcat tgactggttg cggatgcaaa atcttcgtga cattttccaa
    24361 aatgactaga acagagcccg ttacgagaat cacagctgtt accaaggctc ctagcaggct
    24421 aaaccgctta tagcccaagg tgtactgatt gtcttcttca cgattggaga ttgtttctag
    24481 aaaagctgat attccaattg caatcgcatc tcccaagtca tgcacagagt cagcaagaac
    24541 agcgctagaa ccaaatactc cacctgcaat aaactcaaca atggcataag tcaaatttaa
    24601 gaaaaaagcc acccaaacag catattttgc cttcatattt ctcattcctt tgttataata
    24661 gatttatgaa caccttgttc attatcatta tccactaaaa ctcaaagaaa ggatagaagc
    24721 aaaacgtcag ctttattcag ttctgaacaa tttgccttaa gtgtccatat gactaacatt
    24781 gaccgccgta tcagcaaaac caaaaaagcc atctatcaag cttttataca acttttgaat
    24841 gctaagggct acgaggccac tactgttcag gatatcattg atctcgcaga tgtgggacga
    24901 tccacctttt actgtcacta tgagagtaag gagcttcttc tggaccagct ctgccgctac
    24961 ctcttccatc atctttttga aagagagcaa gccatttcaa ccgaggacta cctcgcccac
    25021 ctctttctcc attttcataa aaaccaagac catatcacca gtctgctatt ttccaaaaat
    25081 gactacttcc tccgtcaact ccataaagag ctagaacacc atgtctattc cgtgctagct
    25141 gataatttaa aagaagccca ccctaatctg cctacttctt acctccaaca cttggtcatg
    25201 tccaacttta tcgagacatt gacctggtgg ctcaaaaaag gtcaagattt cacagaccag
    25261 gaagttgtcc aattttatct agaccttctc attcctaaaa attgaatata gagtaaagct
    25321 tcagttgtct tatttctagg ttactgagtt ttttatcttt tcaacaacaa aagaggaccc
    25381 gccgatcctc tttttcatac tataaatcct tgattatcaa ctatatctgt tttaatcgaa
    25441 atctcaaaac agcactttca aacatctttt cctagttaag taaatcagta ttctgcttag
    25501 ctgccttgct ccattgatac caaccaacta gactgttaat gagataaatt agatatttcc
    25561 cttgaatttg caggctttct ccccaccaga gatagattga aaagacattg gtagccgccc
    25621 agaatatcca ctgttcacgg taaacagctg tcatgaggat ttgccctacc ccattggttg
    25681 catctgtgat tgaatcacga tagggacgat tggcaccaat agactgataa atgaagccaa
    25741 aggccaacca ccaaagcaca ctaatggaaa gatactttgt ccagcccttg ccgtccagtt
    25801 tacgcgcgac aaactcctgc ttttccttct taaactgtgc ctgataaatc caaactagaa
    25861 gtccaattgg ctgcatgact gtgaagtaaa gtgtcgtcag cacctcacca taaaagcctt
    25921 tctgtagggc caaaataagg taaataacag agttaatcaa gccaaaaaga taattacttg
    25981 ctcgaccttc cgatacaaag attacacaga taatccctgt caagctacaa atcatcccaa
    26041 tccagtcaac aatacgatgt tcgtaaacca actccagcca gagaggaaaa cttcctaaaa
    26101 ccagcaaata aatccactgg gcaaaactac gatgggcaaa gaggtcatcc cagatagcct
    26161 tcatagttcc tgaaaatcct aaatcagcca tagccgcaac catacgacgg taaccacctg
    26221 acatttcacc tagggttgtt ttgatatttt caattttctt ttgcaaataa gtatgcatca
    26281 tttctccttt tgtttttaaa gagccgtgtc tggatagact ttcggacgca acgctctatt
    26341 agataatgaa ctgcctatac acaagatttc taaccttagt cgacatgagc tgaaacctct
    26401 tatttgttaa gtagttcaca aaatattata cacctatttt atgaatagtc aactgtcttt
    26461 acagtaaaat tttagaaaat catgaaaatt ttctctttct ttccatttta agtgacattc
    26521 agtcattctc acatcaaaaa agcccagacg aaattgtctg agcattcttt tatctagtcg
    26581 tttaaggaag ttgagttcag tatgtttaaa gtctctgtcc catcatttct tcaacaaacc
    26641 ttgttcttgg agaaactcct tggctacttg ctttgctgac ttgccttcaa caccgacttg
    26701 gtagttgagc tggctcatct ggctttctgt aatcttacca gccaatgtat taagaactct
    26761 ttccaactct gggtgtttct tgagaagagc ttctttcatg agtggagccc cttgataagg
    26821 tgggaagagt tgcttgtcat cttccaagac ctgtaaatca taacgctcca attccgcatc
    26881 agtcgaatag gcatccgtga tttgaatatc ccctgactga atagcctgat agcgaagggc
    26941 tggctccatg gtcgctacat tgagattgag accatacatt gattgcaagc ccttatttcc
    27001 atcttcacgg tcgttaaact cgagtgtaaa acctgccttc aactgccctt ccactttttt
    27061 caagtctgaa atggtcttca agccatattc ttgagcaatc tttttcggaa cagctacagc
    27121 ataggtgttt tgataagaca tgggtttgag ataggctaga tgatcctgct tagcaatgcc
    27181 atcacgcgcc acctgataaa cctgttctgg ttcatgactc accttgggtg atggttgaag
    27241 caaactttca gtcaccgtac cagtaaattc aggatagatg tcaatatcgc cttttttcag
    27301 agcttcataa aggaagcttg tcttcccaaa attcggttta acagtcgcag tcatgctggt
    27361 attttcttca atcagcaact tatacatatt ggccaaaatt tctggttctg gacctatttt
    27421 cccagcaata accaagtttt ccttctcttt ttgaaccaaa agagctggac tataagacag
    27481 acccagtaat aaagccacca aggcaaaacc tgagaaaatc gtccgtaatt ttgctttttc
    27541 catcactttt agtaggaagt taaaggcaat ggctagcact gcagaagaaa gtgccccaat
    27601 caaaatcaaa ctggcattat tacggtcaat tcccaaaaga ataaaggaac ctagtccccc
    27661 tgcaccaatc aaggccgcca aggttgccgt accgataatc aaaacagctg ccgtccgaat
    27721 cccagacatg ataacaggca tggcgagtgg aatttcaaat ttcttgagac gttcccatct
    27781 ggtcatccca aaggcaatcc cagcctcttg caggttcgga tcaattccct tcagcccagt
    27841 gatagtattt tgcaaaatag ggaaaatcgc ataaatcact agagctgtca aagccggcaa
    27901 ggtcccaatt cccatcaaag ggataaagag ccccaacaag gccagagacg ggatggtctg
    27961 gaaaatacct gcaatctgca agacccagtc ggccagcttc tcatgatagc gaagaaaaac
    28021 agccaaggga atcgcaagca aaatagctag taacaaggtc aaaagcgaca actgcaaatg
    28081 ttgagataga gctgtcaacc aatcactaaa acgatcctga aaagttgcaa ttaaattagt
    28141 catgaacact acctccaaac aagtctgcta caaagtctgt tgcaggcgct tttaaaattg
    28201 tctcgggatt cgctacctgg cgaatttctc catcctgcaa gacagcaata cggtccgcca
    28261 acttcaaggc ttcatccgta tcatgggtta caaaaatcgt tgtcatccca aactctttat
    28321 gcaattcttt tgtcagaacc tgcaactgtt ttctcgaaat agcatccaag gccgaaaagg
    28381 gttcatccat gaggaaaatc ttgggctgac caatcatagc tcggacaata ccgacccgtt
    28441 gctgttctcc accagataat tcactaggta agcgatgccc atactcggct actggtaaac
    28501 caaccttagc caaaagctct tctgttttct tcgtaatttc ttccttgctc caccccttca
    28561 tttcaggaat gagagcaata ttttccgcaa ctgttagatt tggaaaaaga gcaatagcct
    28621 gtaaaacata accagtagaa agacgaagtt cacgctcatc atagtctttg atgcgcttcc
    28681 catccatata aatatttcca tcagttggtt ccaaaagacg gttaatcatc ttgagcatgg
    28741 tcgtcttacc tgacccagaa ggccctacta aaaccataaa ttccccatcc tcaatctgta
    28801 agttgacatc tctcaagaca tccttttctg tgtagcgcag tgctacattt ttgtattcaa
    28861 tcattctttg tcctcaattt aaaacttccc tcgattggtc aagtcttcta ccttaggcat
    28921 aacttcctta ttatcccaat gctccacaat tttcccgttc tctaaacgga agatatcgta
    28981 ctgggcataa gcaacgccat caatctgagt ctgaccatag ctaaccacat agtttccttg
    29041 tcctaagagt tggaaaacaa agtcaaaagt gacactatat tcagccacat agtttttata
    29101 agcagcactt ccttgtccaa tatcatgatt atgctgaatc aaatcgtctg ccacataatc
    29161 actccactgc tctagctccc cattttggaa aatttctgtc aagaaacggc gaaccagctt
    29221 tttattttct gctttcttgt ccaaatcctt gatttcaaaa tctccaaaaa tttgatctag
    29281 ttggtcattt tcaggtgttc gatagtagtc aacgacatcc caatgctcaa caatacgacc
    29341 attctcatcc gcacggaaag tatccgtcgt cacccattga gcttctccac cattcagata
    29401 ttgatgaaca tgaacaaaga ccagattgcc atcctcaatg gtgcggacaa tcttaatctg
    29461 acgctctgga tgacgctcaa agaaatctgc aaagaaggct gcaaatcctt ctttcccgtc
    29521 aggaacacct gtcgaatgtt ggatataggt atcccctaca gactgggctt gagcctcagc
    29581 aactcgcccg tcttgaatgg catggatgta taggttgtga gcatttttca cttgttgtga
    29641 catattctaa acctcatttc ccttctcttt cagattcgcc aaaattcttt cttgaaaacc
    29701 ttcaaattgg tgaatttctt cctctgaaaa tcctttgtaa aagatagtat ccaatttctg
    29761 actgacacga tgccccactt ctttctggaa cttgcctaac tccgttaaaa ctaaatactt
    29821 cttacgcttg tcttttccac acggactaac aattacaagc ttttgttcct ctagcttttt
    29881 tatcatagtc gtcagcgtat tattcgcaag cccagtcgca agcgcgatat ctgtcgcagt
    29941 tgcgcagcca gtttcactat tccataaaac cgctaaaatc ttgccctgtt cacccctata
    30001 aagagcctca ggatcttgac tcagtaactt ttgaaaaatc cgcccattca acaaacgaat
    30061 atgatgggct agcaaatgac tatctttcat aacacctcca atttatttcg atatcgaaat
    30121 gaataaaata attgtaacac tcatcgttct aactgtcaac tatttcgatt tggaaataat
    30181 ttttgataat tatccacacc accatactcc ggctcaacta acttttaacg agagtttcta
    30241 aactccttcg tcctccagtc tacaaaagcc ttccattcgt actatcctat attttatgag
    30301 gggacacatt tttcctatca gaccatttat tttaaagata gaagtaaatc ataattgctt
    30361 ccatctgttc ttttatagta tattgaagtt agactagagc actgtatctt ctaaaacatt
    30421 gatagaaagc gatttgaatt tcccaatcaa tttgttcgta tttatagcat tttgaaacta
    30481 gaataggaca ccatgactgc taaaagattt ctataaattc atttgatttt cctaatcaat
    30541 ttgttcatat cttatttcat tccgctataa tttcacctta ccctatcttt ttcgtagcac
    30601 ccttcaaaca gcctatcccc taccgtttga cgattcctca cttcgctcca cttccattac
    30661 agaagtttct tcactactat gggctcggct gacttctcat gattccttgt tactactatt
    30721 tgaacgctca cgagatagat cttacaaaaa atgctttgat ccacaatgga atcaaagcat
    30781 tttaaagagt tcctcataca taagcgcaga agtcgcagtt cctctgtact tggcttcttc
    30841 tcttttgata aagcgagcca agttgagcaa ctcaggtgct ggatgtttgg gatttaggag
    30901 caattcacga ttgaccaggc ctgagagacg aactgcctgc aattgctcat ttgtagtagg
    30961 cagtttttta gcagtctcta ggagagcagc aactaaatct tcactcaaat catgtcgagc
    31021 atgattgtaa agatctttta taaggctttc taggtttggt tctgccatcc ctaccacctc
    31081 ccttatggtt taataatgtt taatcaaatc aaccgttgaa cgatccaatt tcttcaccaa
    31141 ggcttgtaag aaagcttgcg cttctaggaa gtcatccatt gcatagaggg tttggtgaga
    31201 atggatataa cgagcgcaga caccgatagt tgttgatggg acaccaccat ttttcagatg
    31261 agctgcacct gcatctgttc cgcctttacc acagtagtat tggtacttga taccagcttc
    31321 ttcagccgtt gtcaaaagaa aatccttcat ccctgggaga agcaagtgac ctggatcata
    31381 gaaacgaatc aaggttccat ctccaatctt gccttgacca ccgtagacat cacctgctgg
    31441 tgagcaatca actgcgagga agacttctgg gtcaaacttg gttgtagagg tatgagcgcc
    31501 acgcagacca acttcttctt ggacgttaga acccagatag agttcattgc cgagtttttg
    31561 acctgataaa gcttcagcta gctcgcttac catgaggaca ccgtagcggt tatcccaagc
    31621 ttttgagatg atattttttt cattggctgt caaaattgca gaactatctg gtacgatggt
    31681 atcaccagga cggatgccaa aactttctgc ctcagccttg tccgcaaaac caccatcaaa
    31741 aacgatatcg gcaatggctg gcatggttgg tccccccttt ccacgagtca aatgcggagg
    31801 aacagaacct gaaatcacag gaatttcatg accatcacga gtcaagagtt tgaaacgttg
    31861 gctgctaacc accatggggt tccagccacc gatttctacg acacggaagg taccatctgg
    31921 cttgatttcg ctgaccataa aaccaacttc gtccatatga gaagcgacca agacgcgcgg
    31981 tgcatccaca gcttctgaat gtttgatacc aaaaatacca cccaagccat ctgtcaccac
    32041 ttcatccaca tgcggtgtca acttttcacg aagataagca cggacaggcg cttcatgacc
    32101 tgagactgca gcaagttctg ttacttcttt aatttttgaa aataatgttg tcatttcagt
    32161 tccttctttc tttcatccat tttaccactt tttataggag aaggatagtg ggaaggtgga
    32221 tttctaagtt agtatcttag tcctgctcta tcttagaaaa ggatagtatt ctcttgcatg
    32281 tagtgcaaaa tctagtaaac attccaaaat taactcgaat atttatttcc aaacaaaaaa
    32341 acaatacacc atcaaagttg tttgtatttt tcatgaaatt tacagaaaat agttgacttc
    32401 cctttcttct ttctttaaat atatagttgg ttgagtttgg aatagtacgc tgtagctgct
    32461 gaaacatttc tagaaattaa tttgactttc ctaatagagt tgttcatatc ttatttcaat
    32521 ttactatagt acaaaactag aaaaggaaaa aatcatgacc aaaacaattc ttgttacagg
    32581 tgggactagc tacattggct cccataccgt taaagctctt ttaaatgctg gctataaggt
    32641 gcatgtcctc gataatctct ccacaggaaa tcgagcggct gtggatagtc gtgctagctt
    32701 taaagaactg gatgtttatg atgctagcgc cttaaaggct tacttagaag aaaatcagat
    32761 tgatgctgtc ctccattgtg caggtgaaat tgttgtgagc gaaagtattg aaaatccaag
    32821 taaatacttc actgccaacg ttgctggtat gaaccaagtt ctcaaagtct tatctgaagt
    32881 tggcattcaa aaaatcatgt tctcttcgac tgcttctctc tatggaaata actgtattga
    32941 caagccagtg actgaagata ccctgctcga ccctgtcaac ccttatgcag agacaaaact
    33001 gatgggcgaa cgaatgattt actggatggc caatcgctac gactggaaat atgttatttt
    33061 ccgttacttt aatgttgctg gggctgaaat ggatgcttca aacggtctgc gtgtgaaaaa
    33121 tccaactcac atcattccaa atatcaacaa gaccgcattg ggacaaaatg atagcttaaa
    33181 aatatttgga gatgactacg atacacgtga cggttcatgt attcgagatt acatttatgt
    33241 cttggacctt gcataggctc atgttaaagg aatgaactac ctatttcaag aagacagttc
    33301 ttctcaaatc tttaacttag gaactaaaaa aggctatact atcaaagaaa tctttaaaac
    33361 tgctgaagaa ttactaaatt aaaaaatccc acacgagatt gttgctcgac gtgctagtga
    33421 cccagccagt gtcctagcag atgcttcaaa agctaaacaa tatcttgatt ggacggctag
    33481 ctactccctc gaagatatta ttttatcaga ttaaggtaaa aacattttag aataggataa
    33541 caaaggagaa agtcttgttg ctctctcctt gttgtattta ttaaattgtc agaaatttta
    33601 ttgacagatt agaaaaataa tgttacattt atatccgcag atatctttcg ataccaaatc
    33661 tacatgaaag gacggggtat gaaactttct cattatttaa ttggcttact tctactccta
    33721 gtctttctct ctattagcat tgggaccagt gatttttcat ggggaaagct atttgatttc
    33781 gaccagcaga catggctcct ctttcaagag tcccgtctcc caagaactat cagtattctc
    33841 ctgactgcct ctagtatgag tatggcaggc cttctcatgc agactattac ccaaaatcag
    33901 tttgctgcac cgagtacagt tggaacgact gaagccgcca aactgggaat ggtgctgagc
    33961 ctttttgtct ttccatcggc tagtctgacc caaaagatgc tcttcgcttt tgtttcatcc
    34021 atcgtattca ccctcttctt cctagccttt atgaccattt ttactgtaaa ggaaaggtgg
    34081 atgttgcctc tgattgggat catctatagc gggattatcg gctcagtcac agaagttatc
    34141 gcctatcgtt tcaatctggt tcagagtatg actgcctgga cccagggctc cttctccatg
    34201 attcagaccc atcagtatga gtggctcttc ttaggcctca tcatcctgat aaccgtttgg
    34261 aaattatccc aaaccttcac catcatgaat ctggggaaag aaatcagcga gagtttgggg
    34321 atttcctact ccctacttga aaaactggcc ctctttctgg tggcgctaac gacaagcgtc
    34381 accatgatta ccgtgggtgg cctaccattt ctcggagtta tcgttcccaa tcttgttcgc
    34441 aagcgctatg gagataatct aagtcaaacc aaactcatgg tcgcactggt tggtgccaat
    34501 ctagttctgg cttgcgatat cctatcccga gttctgatta ggccctatga gttgtctgtc
    34561 agtctcttgc taggaatcat cggtagtctc ggctttatcc tacttctctg gagaggggga
    34621 cgaaaagatg cagactaaaa gcaaacatac caagctcttc tggattctca ttattcttgc
    34681 catcggagct tgtcttctct acttttggcc catcactcac ttgtcagcct ttgcttggaa
    34741 gttgcgttcc caaaagatca tcgtttatct cttggtagcc atcgcgactg ggatttcgac
    34801 cattagtttt caaaccctga cggaaaatcg cttcctgacg cctagtattt tgggaattga
    34861 atccttctac gtcctactac aaaccctact actggttttt gaaagcaagt ttcttcaact
    34921 tggcaaatcc cctatcttag aattcctagt cttacttctt gtccagtccc tcttctttct
    34981 caccttacaa ggttacttga agacactgat gaagcaagac ctggtcttca tcctgctgat
    35041 ctgtctagcg ctcagaagtc tctttcgaaa tatcagcacc ttccttcaag tcctaatgga
    35101 tccaaacgaa tacgataaac tgcaaaatag tctttttgcc tcctttcaac atctcaacac
    35161 ttccatccta gccatcggtt ctctgatcat cctcgctttg acaatctttt tctttcgaaa
    35221 agcagtcgtt ctagatgtct tgcacctgca aagagaaacg gctcagatat tgggactcga
    35281 tgttgaaaaa gaacagaaag agctcctctg gggaatcgtg cttttgacct caacggccac
    35341 tgccttggta ggacctatgg ccttcttcgg ctttatgctg gccaacctca cctacctgat
    35401 tgtcaaagac tatcagcaca agttactctt tatagtggcc attctggttg gatttattag
    35461 cttaaccttg gggcaagcct tgattgaacg agtctttgca ctggaaattc gtatcagtat
    35521 gatcattgag agtgtgggtg gcttcttatt ctttatctta ctatatagga ggtctcgtca
    35581 gtgaaactgg aaaacattga caaatccatt caaaaacagg atattttgca aggcatttcg
    35641 cttgaagtca gtcctcaaaa actgacagcc tttattggtc caaatggtgc tggaaaatcg
    35701 actctcctct ccatcatgag cagactaacc aagaaagatc agggagttct cagtatcaaa
    35761 ggacgtgaaa tcgagagctg gaattcgcaa gaactggccc aagaactaac catcctaaaa
    35821 cagaaaatca attaccaagc caaattgact gttgaagaac tggtcagttt tggacgtttt
    35881 ccctacagcc gaggtcgact tagatcagaa gactgggaaa aaatccgaga aactctgaac
    35941 tatttggaac tgaccaactt aaaagaccgc tacatcaata gcctgtcagg ggggcaactc
    36001 cagcgcgtct ttatcgctat ggtactggcc caggatacgg actttatctt gctggacgaa
    36061 ccactcaaca atctcgatat caagcaaagc gtcagcatga tgcagattct tcgacgactg
    36121 gtggaggaac tcggcaagac cattatcatc gtcctccacg atatcaacat ggccagtcag
    36181 tatgcagatg aaattgtcgc cttcaaggac ggccaggtct ttagcaaggg aagcaccgat
    36241 caaatcatgc aggctgacct gctcagtcaa ctttatgaga ttcccatcac gctagctgat
    36301 atcaatgaca aaaagatctg tatctatagc tagtaacata aaagctcaag ttagagaacc
    36361 ttcagtctct tagtcaataa gattaagaga ctccctaaat cgttatcaca ttttaaaaag
    36421 gagaaattat gaaaacatcc cttaaacttt atttcactgc cctagtggcc agcttcttgc
    36481 tcctacttgg tgcatgtagt acaaactcaa gcactagtca gacagagacc agtagctctg
    36541 ctccaacaga ggtaaccatt aaaagttcac tggacgaggt caaactttcc aaagttcctg
    36601 aaaagattgt gacctttgac ctcggcgctg cggatactat tcgcgcttta ggatttgaaa
    36661 aaaatatcgt cggaatgcct acaaaaactg ttccgactta tctaaaagac ctagtgggaa
    36721 ctgtcaaaaa tgttggttct atgaaagaac ctgatttaga agctatcgcc gcccttgagc
    36781 ctgatttgat tatcgcttca ccacgtacac aaaaattcgt agacaaattc aaagaaatcg
    36841 ccccaaccgt tctcttccaa gcaagcaagg acgactactg gacttctacc aaggctaata
    36901 tcgaatcctt agcaagtgcc ttcggcgaaa ctggtacaca gaaagccaag gaagaattgg
    36961 ccaagctaga caagagcatc caagaagtcg ctactaaaaa tgaaagctct gacaaaaaag
    37021 cccttgcgat cctccttaat gaaggaaaaa tggcagcctt tggtgccaaa tctcgtttct
    37081 ctttcttgta ccaaaccttg aaattcaaac caactgatac aaaatttgaa gactcacgcc
    37141 acggacaaga agtcagcttt gaaagtgtca aagaaatcaa ccctgccatc ctctttgtca
    37201 tcaaccgtac ccttgccatc ggtggggaca actctagcaa cgacggtgtc ctagaaaatg
    37261 cccttatcgc tgaaacacct gctgctaaaa atggtaagat tatccaacta acaccagacc
    37321 tctggtatct aagcggaggc ggacttgaat caacaaaact catgattgaa gacatacaaa
    37381 aagctttgaa ataagccact tcaaactcaa tttaatactc aatgaaaatc aaagagcaaa
    37441 ctaggaaact agccgcaggt tgctcaaaac actgttttga ggttgcagat gaaagctgac
    37501 gcggtttgaa gggattttcg aagagtataa aattttgaca ttctaaaacg catcctatca
    37561 agttcactca aacctgatag gatgcgtttt tatcattttg aaatctattt accccacctc
    37621 attccccttc ttgatttcgt ttaagggaaa agtggtctgg aacggggtcc ttacctgttt
    37681 tcgaccaggg atgacaacgt aaaatccgag ccaagcccat caataccccc ttaaaaccat
    37741 gtttttcaat agcctgaatc atgtagttgg aacaagtcag ctcaaagcga caagagggtg
    37801 gaaagactgg tgagataaaa cgttggtaaa agcgcacagg cgctattaaa attcgtttca
    37861 ttatttctta gttacagcca tggtgtgtag ttggctgatt tcttttttat taagacgacg
    37921 ggattctcct ggacggagtc ctgtcaagtc taggtgtccg aaacgagtcc gagacaactt
    37981 atctacttgg agaccaacag cttcaaacat ctttttaacc tgatggttac gcccttcatg
    38041 gatggtcaac tgcaccacag agcgattttt gactgggtcc actttgagaa tttcataaac
    38101 agctggcttg gttttcttac catcaatctc aagaccacgg gtcaaggggc ggagattgtc
    38161 cttattggcc acacccttaa cacgcgcgac ataaaccttg tcaatctcat tacgagggtg
    38221 aatcatctcg tctgtaaagt ccccatcatt ggtcaaaatc aagacacctg atgtatccca
    38281 gtccaaacga cccacagggt aaatacgctc tttgacattg ggcaagaggt cgacaaccgt
    38341 cttgcgaccc ttatcatctg tcacactgga aatcacaccg cgtggtttgt taagcagata
    38401 gtagaccttt tcttcgttgt agataggttg accttcaact tcgaccttgt cgcctgactt
    38461 gatagtggtt gctagttcac gcaccacttg gccgttaacc gtcaccaagc cttgcttaat
    38521 cagctcttct gcttttctcc tactggccac acctgcgtgg gcaatatact tattgattct
    38581 catcttcttc tatcctttca ccaaataatt ggctttcttg ggcttgaatc tcaagctcat
    38641 caatcactgg taattcttct aaatggttta tccccatgta atctaggaaa taatccgtag
    38701 tcacatagag gttggggcgc cccaatactt cctttttccc gtcttccttt atcaggtcaa
    38761 aagcctgcaa ctttgccaag gctccactcg agttaactcc acggatggca tcaatttcta
    38821 tccgcgtaat cggctgtttg taggcaataa tggacaaggt ctcaagggca gcccgagaca
    38881 agctctggtt gataggcgcc ttagagtatt ccttcaaaat ctctgcaaat tgagacttgg
    38941 tcaccaatct ataagcacca cttgtctcaa tcaaagccaa actggaatct gggtcctttt
    39001 catacttctg ggctaatttt cctaaactct gctggatgcc tgtcggtggc agagagagga
    39061 gttcagctaa ctggcggacc cgaatcccat cttcacccgc tacaaacaag agcgcttcta
    39121 tttttgctaa agtactcatc tttcctctct atcaagtcta gctttgaggc acttgacttt
    39181 cttccttctt ttccatgaga tagatatctc caaaactctc ctcttgcacg aggatcagct
    39241 cctgggtttt gattaactct agggttgcca aaaagagggt gatgacctct tggacattct
    39301 gggcttcctt gaacaaatcc tgcaagcgca attgatctcg tccaatcaag gactctttca
    39361 cgataatcat catgtcctca atcttatact catcccgcaa gatagtcgtg tgattttgtg
    39421 caaactcctc ttttttcttg gctaggatat ttgaaaaagc caaaaagagg tcaatggtcg
    39481 tcttgtcatg cacaagctcc gcatcttcgt aaatcaactc tgtcggcgct ttggaataat
    39541 actgggcccg ttcttggtgc ttggcttcca agtgctcacc caagagcttg aacttgcgat
    39601 attcttcgat ttgagagagg aggtcctgct ccaggtcatc ccccaagtct gtcacttctg
    39661 ctaccttcgg aaggagttta cgactcttaa tcagcatgag ctgactagcc atgaccatgt
    39721 actcacccgt cacttccaga cgcatggcct gcagggttga aacataggct agatactgtt
    39781 cgatgacttc cgtaatgggc acatcgtaga tatccatctg gtacttagaa accagatgca
    39841 agagcaagtc cagggggcct tcaaaatctt ttaatttaat atccattatc tatatttttc
    39901 taaggtcagg actgttttta atcctaattt ttttgcaatt tcgtacaaat cgaccttgtt
    39961 ttctatttgt cttagaataa actgttcacg taagacttga gctgataagg atggaaaacc
    40021 tttctccttg acaaaagatt ctaactgacg aaaggcccac tgacgagaat agggtttctc
    40081 tcctctttca aaaagatagg tctgccccat caagggttcc aattctgaaa gcaaggccgt
    40141 gggaatggtg acaatcctct gttgggaagc cttgctgatt cgcaacacct gaaaatccag
    40201 attgatgtcc gcaaccttga tggctaaaat ctcactgggc aagagcccca tttctaggat
    40261 taagagcgct agcaagcggc cctctggatg gtcgctttcc tgccaaaaag agtctaggta
    40321 tagaatctct ggcttttccg tcttcttttc agcttgtttg gctaattcca agcggtaaaa
    40381 gctgtccacc tctccttttt gatagagaaa gtatagaaat tggttacagg ccgaaatctt
    40441 tcgcttctgg gcgctgattt ttagattggc tagctgggct tggtaaatct tgagactggt
    40501 ctcagaaatc cgctcaccta ccatgtctaa aaattgctcc aaatcatact tataggactg
    40561 cttggaattg acagacaagc cctgcttttc ctctaaaaag gctgaaatcc tgtctctcat
    40621 tggcatcgaa tctcatattc cttactaaag tcatgcaaga gggcattaac ggccttgagg
    40681 atggacttac gcgtaataat cccttggaaa ataccctctg catccacaac cggtaagaag
    40741 gactcatcta ctagcttgtg caagacctcc gtaatggtga aatcaggcga aacaaccgct
    40801 acgtccgttt ttgtcatatg aacgatatcc gtatccgcca tgatttcttg gctcaagtca
    40861 tgctccatct gataagccat aatatctctg agtccaatcg tcccaacaaa ctgtttttca
    40921 tctgtcacaa cgggaacacg ggtataggtc atctgactga gcaagagggt cgcatgatcc
    40981 gcattgtggg tatcaatcaa cacagctaga tttttagcag gggtcaaaaa agtttcctcc
    41041 tgccccaaca agaaagtctc aaactccttg gcaatcatcg gctaaactcc ttggacaaac
    41101 ctggatacac ctcgtgatct cgtgtcaaaa agtccacttt gaagtaacta tcatcaatct
    41161 ccacacgagc atagagacat tctctgatgg tacctcgtgg ttgactgata gaacctggat
    41221 ttagaaagag gatcttgcct tccaaccaag cacttggcac atgcaagtga ccatagaggc
    41281 agatagcggc ctcttcctcc tgagcccagt agtccaactt ttgaaagttg aaattgatgt
    41341 caaacaagtg accatgagtt tggataatct tggtcgaacc aagctcagtc accagacgtt
    41401 ctgggtagcc ggcgtagaag tccatgtttc ctttaacaac gcggatgccc tcccaaagtg
    41461 gagaatccgg acgtagttca gaatcgccgt tatgaaaaac ggcatcgact ttgcccacat
    41521 agcgatcacg gacttcttcc acaatcaagc tatcgccatg ggaatcgctc attacaatga
    41581 tggtttgctt tgccatgatg gaaatacctc caaaagtttc ttaacggcta aggcacggtg
    41641 agattgacta tttttttctt ccagggttaa ttcagctgat gacttacctg tctctcctac
    41701 aaggaagagg ggatcatagc caaagccatt ttcaccctta ggttcaaagt taatataacc
    41761 tgaccagtct gcttcaacaa ctaaactttc cttatttggg ctggctacga ctagggttgt
    41821 gtggaactga gccgagcggt ccttgagttc aaagaccatg gccaattcgt gcaagagttt
    41881 ggcattattt tcacggtcag ttgctcccac acctgcgaaa cgagctgacc agacgcctgg
    41941 taagccacca aggacatcga ctttgagacc agaatcatct gccaaaacca tcttgcccgt
    42001 taattgagaa atggtttctg ccttaaggcg ggcattttct tcaaaggtca tacctgtttc
    42061 tgctacttca ggcaggtcag ggtagtcatt aagattttcc acatcgtagc ctaacttatc
    42121 aaagatagct cggaattcct tggttttgcc ttcgttacga gtcgcaatca acaaggtttc
    42181 tctgaccttg cttgtctcaa agaaatcatg aacattgacc ccttctttag gcaattctac
    42241 atacaagagt tgcccatttt caaccaagag cagggcccca tgacgttgaa taacttccaa
    42301 gtttcgtccc atttcttgat taagcatgtc taccacaaag gagaacaaac ggtaggtaga
    42361 accatagcgt aaaacagtaa ctgaaagcgg gaaaccatac tcttcatctc caaatatttt
    42421 ggagaattca aacagaggaa aatctgtctt atagtcgctc aaactgttaa cgccaccaaa
    42481 aatactataa gacccaacat accaatcctg gtcatcctta tattcataaa ttttatttgt
    42541 cataattcta catgctccac ataaatctct ttttccagcc attcttcacc aatttgtgca
    42601 aaactttggc tactggctgt tgtgtaaaaa cggtgatgga gtggtccagc atcgcgacca
    42661 cgattgattt caaaataatt gagtaagact gagatatccc gtacgcactc tgccccacta
    42721 tcgatgagct gaacctttgg ccccatgaca ttttggataa tagggcgaag gagtggataa
    42781 tgagtacagc ccaaaatcag gctatccacc tttccaacca agggacgcag ggtttcatag
    42841 accaccttct tggtaacact ggttgacagg gcacctgact caaccaaggg agcaaacttg
    42901 ggacaggcca agctctccac ctgtaagtcg ggatccagat catggatttt ctgacggtat
    42961 atgtctgatt gtaccgtcat gggcgttcca atcactccga ttttcccacc ttgactggac
    43021 ttgatggctg ccgaagctcc tggcaaaatt acacccaaga caggaatatc tagttgagcc
    43081 ttgatttctt cccagacgac cgcagtcgca gtgttacaag caatgacaat cattttgaca
    43141 tccttggtca agagaaagtt gaccagctgc caagtatatt cacgaatttg ctcagctgga
    43201 cgggggccat agggcgcccg cgccgaatct ccaatataga cgatttcttc atggggaagc
    43261 tggcgcatga gctcgcgcac aacggtcaag cccccgacac ccgaatccaa aaaaccaatt
    43321 ggtcgattat ccatacagtc ttctttctag tcttttttct gattgatcgt tcattatgat
    43381 tccttgtact gaacgaactg accgacagct tgatagaatg tcaactacct ctctcttaat
    43441 cataatcaaa tatcaataga atgcaaggaa aaagtctcat ccctaaacca taaccaacat
    43501 agtgagaagt ctggaacttt catcccagac ttttccttat ttattttttc tttttattgt
    43561 tagcaagggc tgccttttgt tggcggatga tttggtggta aacttgttgt accttagctt
    43621 cgcttggttt ttgaccattt gcactcaaaa gagtacgaac tgcttcagca ttcaaacgtg
    43681 ggttgtcagc aaattctttt tcgatttgct tacgaaccaa gtacattcct ccaagagctc
    43741 ctcctagaaa agctagcaca atcaatacaa ttgctaaaag taaatccatc atttttctcc
    43801 tgtttctttt tgagtccctt tcattatacc acaaactagc caccctgacc agtttgttct
    43861 acactttcag ggatggaata gacagcaaaa agaaccctgc ttttctgaaa aagaggtctc
    43921 cttgctaagt ttaatttaca taaatagcca gtgtttgata gggttttagt agaattttct
    43981 cagacacttc tgcatcttca tagtttgaaa tcaaaatctg tccattttgg tagactgctg
    44041 gcaagtcgat ttccacttct ttagcataaa agttattgag cactagtaac ttttgatcct
    44101 caaactggcg ttcaaaagcg tagacttgtt tgctatcttc aaaggctggt ttgtaacttc
    44161 cttctgaaat gattggcatt tccttacgca gtcgaatcaa gtcttgatag aaggtaaaaa
    44221 tcggaccctg gatttcattt tctacattga tgtctttata ggatttacca gctttcaacc
    44281 aaggagtgcc tgttgaaaat cctgcatttt ccgaagcatc ccactgcatg ggaatgcgtg
    44341 aattatcacg cgacttagct tgaataatct ggaaggcttc ttgctgactc tttccttctt
    44401 ctaggagcat ctgataggca ttaagcgatt cgacatccac gtaatcagcc atagaatcat
    44461 agtctgggtc aatcatcccg atttcctcac ccatgtagat ataaggtgtc ccacgtgaca
    44521 ggtgaatgct ggctgctagc atggtggctc cttccttgcg gaagttttga atatcgacaa
    44581 aacggttcaa ggcacgtggt tgatcgtgat tgttccaaaa gagggcactc caaccgtctt
    44641 tatcactcat ttccttaccc caactatggt aaagactctt caactcttca aaatcaaagg
    44701 gagccaaggt ccacttttgt ccatccttat agtccacctt gaggtgatga aaattaaagg
    44761 tcatggataa ttcctgacga tcaggcgacg aatagaggac acagttttcc atggtggtag
    44821 aagacatttc cccaactgtc ataaagctat cgtcagatcc aaaagtggct tggttcatca
    44881 tacgcaaata gttatgaacg atgggtttgt ctgtataagc tggcttccct tcattttcag
    44941 gacagtccac tgaaacctcg tccttaccaa tcaaattgat cacatcaaat cgaaaacctt
    45001 tgacaccctt gtcgcgccag aaattaacaa ccttgaaaag ctccttacgg acattgggat
    45061 tgcgccagtt aaggtcagcc tgggtctcat caaataggtg aagatagtat ttcccagtat
    45121 ccccgaaagg cgcccatgca gaaccaccaa acttagactg ccaatctgtt ggttggtctt
    45181 ggatgaagaa aaagtcttga taatacttat caccagctag ggctttctga aaccattcat
    45241 gctctgtcga acaatgatta agtaccatgt ccagcataaa gtcaatcttg tgctctttac
    45301 cgatacacac catttcctca aaatcagcca tatcaccaaa aagaggatcc actgccatat
    45361 aatctgaaat atcgtaacca ttatcccgtt gaggacttgg atagaatgga ttgagccaga
    45421 ccatatccac acctagtttg gctagatagg gaatttttcc gataatccca cggaaatccc
    45481 caataccatt gccagtggtg tctttgtaag attttggata gatttgatag actacttttc
    45541 ctttatcaag tgtcatctgt ttctcctttt ctgataaaag ggaggaagca gtcttccgtc
    45601 cctatttgtg ctatttcaat tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    45661 cacaggttgc tcaaaacact gttttgaggt tgcagataga gctgacgtgg tttgaagaga
    45721 ttttcgaaga gtattagatt cgtgtagcga ccatgagaga tgctccagct tgaatcgttg
    45781 tcggataagt tccgggaata gtcgctgtat aagcatcttg gttggtgatg ataacaggag
    45841 tttctgtcac cagacctgca gccttaatga catccatatc aaaacgaatc agttgctgac
    45901 caactgtaac gtgatctcct tggactacaa gactttcaaa acctttgcca tcaagaccta
    45961 ctgtatccat accgatgtgg atgagcaatt caactccctc gtcagagaca atgccgatgg
    46021 catgcttggt agggaaaaga accgtcactg tcccattaac tggagaggtc aactcacctt
    46081 ggcttggttc aatgactaga ccttgcccca tgacacctga tgcaaaaata ggatccgtcg
    46141 cttgactcaa ttctttcact tggccagtta gtgggctgat aatttctacc gaagtaagtt
    46201 ctactggttc atggttcaca aattctgctt cttcttgagc aacgaattct gcctgcaagt
    46261 tcgtatcgcc ctctgttttt gtaaagagac cagccttgcg gaagaagaaa gtcaagagca
    46321 ttggaacaac aatcgcaact agcatagttc ctgcaaatgg cagcatgtat tgaggttgaa
    46381 tagagagaat acctggcaaa ccaccgatac caatagaagc cgcagttaca ttaaaagtaa
    46441 cggataacat gcctgcaagg gctgaaccag tcatcccagc aacaaatgga taaatatatt
    46501 ttacgttaac cccaaaaaga gctggttctg taacaccgag ataggctgaa atggttgcag
    46561 gaagtgaaac ctgagcctca cgctcatcat ggcgatgcat gaaataatag gcaaacacgg
    46621 ctgagccttg agcaatatta gaaagagcaa tcattggcca tagggcagtg ccaccagcat
    46681 ccgcaatcaa ttgtgtatca atggcattgg tcatatggtg cagacctgtg atgacaaatg
    46741 gagcgtagag ggcaccaaaa attgcaccga agagccattt aactggacca gttaaacctg
    46801 ccaagacaac tgatgaaagt ccttgtccaa ttgtccaacc gattggtccc aaaacagtat
    46861 gagccaaaat caaggctgga atcaatgaca agaaaggtac aaaaatcata gaaatgactt
    46921 ctgggatatg cttgcgccag aagatttcaa gataagatag actcaaacct gcaagcaagg
    46981 ctgggataac ttgggcttgg taaccgatac gattaacagt aaaatagcca aaattccaaa
    47041 cccagtttgc cgcgatatca gctgctggcg ttgaagcaac cgcataggca ttgagcaact
    47101 gaggcgatac caaacagatt ccgagaacaa ttcccaaaat ttggctggtt cccatcttac
    47161 gagaaacaga ccaagtaatc cctactggta agaactggaa gatagcttca ccaggcaacc
    47221 agaggaaatg attaacacct gcccaaaact gagaggattc tgtgatggtc ttgccatcca
    47281 acatcgacca atggacacct tccaagacat tacggaaacc gaggatcaat cctccgacta
    47341 tcaaggctgg aataatcgga gtaaaaatct ccgccagagt ggtcatgaca cgttggacca
    47401 cgttttgatt actcttagct gcagacttgg ctgcttcttt ggaaacaccc tcaatacctg
    47461 aaacagctgt aaaatcatta taaaagatgg gcacgtcatt tccaatgatt acctgaaatt
    47521 gacctgcatt tgtaaaggtt cctttaacag ctggaattga ctcgatagct ttaacattag
    47581 ccttcttatc atttcctaaa acaaagcgca tccgtgttgc acagtgagtt acggcagtca
    47641 cattttcttt gcctccgatt gcctgaagca gatctttggc ttcttgttca aattttccca
    47701 tttgattctc cttatacttg tcaaagcaag tttgatttga taagtatatt gtaaacgata
    47761 ccaaacttgt ctgcaacttg tttggtataa aaagggtgtt tttttgtaaa ttttctagca
    47821 cttgtatggt aaaatagata caggtgttca ttaaactaga ctaaaaacct atttaagcag
    47881 gcaaaatgaa gaaataccaa caattattta agcaaatcca agaaaccatt caaaacgaga
    47941 cttacgctgt cggagatttc cttcctagcg agcacgacct tatggagcaa tatcaagtga
    48001 gtcgtgatac cgtccgaaag gccctgtctc tcctccaaga ggaaggattg atcaaaaaga
    48061 taagagggca aggttctcaa gtcgtcaaag aagaaaccgt caatttccct gtatccaacc
    48121 taaccagcta ccaagaacta gttaaagaac ttggactgcg ctctaaaacc aacgtggtca
    48181 gtctggacaa gattattatt gataaaaaat cctcactgat aaccggtttc ccagagtttc
    48241 ggatggtttg gaaggtggtc cgccagcgtg tggtggatga tctggtatcc gttctggata
    48301 cggactatct ggatatggaa ctcatcccaa atctcactcg ccaaattgct gagcagtcta
    48361 tctattctta tatagaaaat ggcctcaaac tccttattga ttatgctcag aaggaaatca
    48421 ccattgacca ctcaagcgac cgagacaaga ttctcatgga cattggcaaa gacccttatg
    48481 tcgtttcgat taaatcaaaa gtctatctcc aagacgggcg ccaatttcag tttaccgaaa
    48541 gtcgccataa gttagaaaaa tttagatttg tagattttgc aaaacgcaag aaataaaaga
    48601 ctgagacacc agatctcagc ctttttcttt atcccaaaac taattcatca ctgaccagac
    48661 tttggccact atttttctgg aagagatgca taaggtcttc aactgtcaga tgctttttct
    48721 cttctccctt gacatccacc actatcttgc cttgatagag cataatgaga cgattgccgt
    48781 actcaatcgc atgattcata tcatgggtaa tcatcaaagt cgtccactga tggtactcca
    48841 caatcttttg cgtcaagtcc atcaccattt gactggtttt cgggtcaagt gccgcagtat
    48901 gttcatccaa aagcaaaagt ttgagtttca ccagagctgc catgactagg gtcaaagcct
    48961 gtctttgtcc tcctgagaga tattgagtat ctacttttaa gcggttttca agaccaatat
    49021 tcaactcctt caaggcctct tggaactgga ttctatcctt ctccttcacg ccccaaccaa
    49081 gccctctctt ttgcccacgt ctcaaggcaa tagccatatt ctcctcaatc gtcaaacgag
    49141 aagctgttcc catcttagga tcttgaaaaa cacgggcaat atccttggct ctctttctga
    49201 cactcagatg tttaatggat ttccctgcca gtagaaggtc cccttcgtcc accgatagat
    49261 taccagccaa gatattcatc aaagtggatt ttcctgctcc atttccacca atcacagaga
    49321 taaaatctcc ctcttcaacc tctaaatcta atcctttgag gacatggttc tcattgaccg
    49381 tccctgcttc aaatgtcttg tgaatatttt caagtgttaa caaacttgcc ataactttct
    49441 cctcctattc atttctcaat ttcagaccac gaatctttaa tctcttttgc aatgctggtg
    49501 caaataaaac caaagcgagc aagattgcat taaagagacg taccaagttt tgatctagat
    49561 ttggaatttc atagatattt aaaataatca aacggtaaac aatagcaccg attccgatgg
    49621 ataataagcg gcctccaatg gtcaagtcgt gtatcaagac ttccgagctc aaaccaacaa
    49681 caatggttcc tgtcccagaa gtcacatctg aaaatccatc attttgggca aacaaggaac
    49741 cacatagggc aatcaaaccg gttgaaatca tgtaaccaac aatcttcatg gtgtttacat
    49801 tgactccatt ggcctcactc atcgggatat tgtccccagt cgaacgcaag accaaaccaa
    49861 tctctgtttt catcaaaagg gtcaaaacca aacaagtaag agacagacta aactaagtga
    49921 gaaaacagct ccttcatttg tcagacccaa gctcgccaac tgtttaaaga cggttgcaga
    49981 atctcccaag gaaagattgg gtacactgcc catgatttta atattgattg aatagagccc
    50041 tgtcaaggtc acaatccctg tcaagagagc tgggattttc atcttggtgt ggagcattcc
    50101 tgatataaga cctgctacca tacctgccag caaagcaagt aaagtcgcaa gccaaggatt
    50161 tgcccctgcc tgtatctgtg atacaacgat tgctgccccc ataggaaagg ctccctcagc
    50221 agtcatatcc gcaatatcca aaatacggaa agtcaagtag accccaattg ccataatcga
    50281 ccacaacaaa ccttctgata aactagataa cacaaaattc atcttaatcc tccttattcc
    50341 ttgccttcta acttactaat atcaattcac aatgcatctg ccatttcttg attagtatgc
    50401 aattccagtt tttcaggcaa ctcaactgct atattttctg gttcctcacc ttttaaaaca
    50461 cgaatcagca tgcgagctgt ctgtcttccc aattcttcat aattggttcc gtagttatac
    50521 aagccaccaa cagcaatcat ttctgttgaa ccaccgaata ctggaacctt gtgtttaata
    50581 gaaacctgct taactgtttc catggttgac gaaatgatat tatcagttgg gacaaaaacc
    50641 atatccacct ctgccatcaa actctctgct gccgccttga cgttattact gtccaagatt
    50701 gttttttcaa caacggtaaa gcctttttct ttcagaaatc gcttagcttc atccttttaa
    50761 acaaccgaat tgggctcgct ctgagtatag aggattccaa tcgttttagc ctttagcaac
    50821 actttcttta tcaaattgat ttgggttgaa atggcatctg atgactgatc gcttgtccca
    50881 gttacattgc ccccaggatg ttctcttgac tcaaccaact tggcactgac tgggtctgtt
    50941 acagctgaaa agataactgg tgtcgtttgc gtcgtattgg ccaagctctg agcagaaggc
    51001 cttgcgatgg ctagaacgac atcgctggat tctgctagtt gctgggaaat cgtttttaga
    51061 tttctttgtt ctccctgtgc attttgcaaa tcaatctcaa tattttcccc ctcaacatag
    51121 ccttgtttgg ccagctcatc cacaaatcct tctctagtag cgtctaagga ctggtgggta
    51181 ataaactgcg aaataccgat acgaaagaca tctcttttct tatctgcctt caactgatgc
    51241 aaactgatca gagaagtcaa gaggatcccc actaccaaga gggggctagt gattttcgaa
    51301 caactttcat aatgaaactc cttctcagaa aagataaaac aaaaaaacgc ctagatacta
    51361 tctaaacggg tacttgaaat aacctaacaa gttacaactt agctggtcca tttagatatt
    51421 catctatatg gaccacaatc aaaaatctta gccacataga tacaaacaaa ttgcttgaac
    51481 tgtttgcatc catggtgaca tgtctacaaa cactatctaa agtagctaaa gtaaaagttt
    51541 tgattcatag ttacggcttg tctcttattc atttcttttt ctgctttctt ttttgatcct
    51601 tcctatccta ccaccttttt catcacctgt caataatatt tcaaaatttt ttaaaatttt
    51661 tcgaaaattc tttcag
//
LOCUS       DAVAZV010000007        50102 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVAZV010000007 DAVAZV010000000
VERSION     DAVAZV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.007"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..746
                     /locus_tag="VQT46_000395"
     CDS             <1..746
                     /locus_tag="VQT46_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2370486.1"
                     /translation="YELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTD
                     KKFVFIIDEINRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVY
                     IIGTMNDIDRSVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAA
                     IENVQELNSHYHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLK
                     KAFELTNNEQKDQAVADDNESDENDDADY"
     gene            733..2085
                     /locus_tag="VQT46_000396"
     CDS             733..2085
                     /locus_tag="VQT46_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET2370487.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKKQKILETINQEIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLVFPSKDKVIDNEMGNL
                     AGYGALLKKWSIQIPQKSSSYSAFCKMMENSDYSAFCKMMENSEENFKAIIDEEVGRK
                     "
     gene            2260..3246
                     /locus_tag="VQT46_000397"
     CDS             2260..3246
                     /locus_tag="VQT46_000397"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET2370488.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKQMHDQGLIASISVGVKDYEY
                     DFVSQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            3310..3381
                     /locus_tag="VQT46_000398"
     tRNA            3310..3381
                     /locus_tag="VQT46_000398"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3343..3345,aa:Arg,seq:ccg)
     gene            3564..4262
                     /locus_tag="VQT46_000399"
     CDS             3564..4262
                     /locus_tag="VQT46_000399"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET2370489.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFDQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVMIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            4253..7792
                     /gene="smc"
                     /locus_tag="VQT46_000400"
     CDS             4253..7792
                     /gene="smc"
                     /locus_tag="VQT46_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET2370490.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKSEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDNLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDMHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDAITVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDAVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLRSEEAALKTLQDQMATLTERLEVIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEIDRLSEGDWQADKEKCQDRLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEEAKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRYLQSQLTDQYQISYTEALEKAHELENLNLAEQEVQDLEK
                     AIRSLGPVNIEAIDQYEEVHNRLDFLNSQRDDILSAKNLLLETITEMNDEVKDRFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            7789..8583
                     /locus_tag="VQT46_000401"
     CDS             7789..8583
                     /locus_tag="VQT46_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2370491.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGETWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKDQSVIAYMEGL"
     gene            8583..9401
                     /locus_tag="VQT46_000402"
     CDS             8583..9401
                     /locus_tag="VQT46_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2370492.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKATLKAASDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGHEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKAAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            9405..10625
                     /gene="ftsY"
                     /locus_tag="VQT46_000403"
     CDS             9405..10625
                     /gene="ftsY"
                     /locus_tag="VQT46_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET2370493.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAVLEESQDSEPAVGVSQEEIEELPEEEKLEHEGTIEENNSEVLEAERPQTEETVQ
                     EKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEELLIMSDVGVQVASNLTEELR
                     YEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTTS
                     IGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDG
                     MERAVAEGIDILMIDTAGRLQNKDNLMTELEKIGRIIKRVVPEAPHETFLALDASTGQ
                     NALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPVKLIGFGEKIDDIGEF
                     NSENFMKGLLEGLI"
     gene            complement(10671..12158)
                     /locus_tag="VQT46_000404"
     CDS             complement(10671..12158)
                     /locus_tag="VQT46_000404"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET2370494.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPAIFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVGASWKLIDRIEELWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(12307..13047)
                     /locus_tag="VQT46_000405"
     CDS             complement(12307..13047)
                     /locus_tag="VQT46_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2370495.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDNLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(13047..15212)
                     /locus_tag="VQT46_000406"
     CDS             complement(13047..15212)
                     /locus_tag="VQT46_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET2370496.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALAEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            15385..16338
                     /locus_tag="VQT46_000407"
     CDS             15385..16338
                     /locus_tag="VQT46_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2370497.1"
                     /translation="MKNKRIFKDFQASKMNLNLYTSPLLAFVFVFIGEFVAYTLYGIS
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENCLSNLLKGFSLGLALFLLTLLSLVVLGQYRLESIHLNPYYLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            16415..18403
                     /gene="uvrB"
                     /locus_tag="VQT46_000408"
     CDS             16415..18403
                     /gene="uvrB"
                     /locus_tag="VQT46_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET2370498.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAIAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            18413..18976
                     /locus_tag="VQT46_000409"
     CDS             18413..18976
                     /locus_tag="VQT46_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370499.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKTNDGYYQINGNS"
     gene            18942..19430
                     /locus_tag="VQT46_000410"
     CDS             18942..19430
                     /locus_tag="VQT46_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370500.1"
                     /translation="MTVIIKSMETPEEIEGKPLVHWQTWREAYDGLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAMDGMKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LIKAALIALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDEQEKILELGKPIKEKRMVFY
                     SK"
     gene            19503..19970
                     /locus_tag="VQT46_000411"
     CDS             19503..19970
                     /locus_tag="VQT46_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2370501.1"
                     /translation="MSRAQLTILTNICLIEDLEAQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMEASDKSEFFYPRRTEDDWEKKIF"
     gene            complement(19967..20482)
                     /locus_tag="VQT46_000412"
     CDS             complement(19967..20482)
                     /locus_tag="VQT46_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET2370502.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFKPLSELTDGVHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(20494..21021)
                     /locus_tag="VQT46_000413"
     CDS             complement(20494..21021)
                     /locus_tag="VQT46_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2370503.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGSLYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            complement(21299..21862)
                     /locus_tag="VQT46_000414"
     CDS             complement(21299..21862)
                     /locus_tag="VQT46_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2370504.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQT46_000415"
     CDS             complement(21846..22397)
                     /gene="coaC"
                     /locus_tag="VQT46_000415"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET2370505.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQT46_000416"
     CDS             complement(22409..23098)
                     /gene="coaB"
                     /locus_tag="VQT46_000416"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET2370506.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            23328..24998
                     /locus_tag="VQT46_000417"
     CDS             23328..24998
                     /locus_tag="VQT46_000417"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET2370507.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELEIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNALSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            25326..26501
                     /gene="mutY"
                     /locus_tag="VQT46_000418"
     CDS             25326..26501
                     /gene="mutY"
                     /locus_tag="VQT46_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET2370508.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     LIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            26556..27260
                     /locus_tag="VQT46_000419"
     CDS             26556..27260
                     /locus_tag="VQT46_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2370509.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            27253..28602
                     /gene="vicK"
                     /locus_tag="VQT46_000420"
     CDS             27253..28602
                     /gene="vicK"
                     /locus_tag="VQT46_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET2370510.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            28604..29413
                     /locus_tag="VQT46_000421"
     CDS             28604..29413
                     /locus_tag="VQT46_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2370511.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            29504..29746
                     /locus_tag="VQT46_000422"
     CDS             29504..29746
                     /locus_tag="VQT46_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET2370512.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            29748..30002
                     /locus_tag="VQT46_000423"
     CDS             29748..30002
                     /locus_tag="VQT46_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET2370513.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            30049..30822
                     /locus_tag="VQT46_000424"
     CDS             30049..30822
                     /locus_tag="VQT46_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET2370514.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFTTKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLAKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPASIFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLKDELSSQRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(31082..32068)
                     /locus_tag="VQT46_000425"
     CDS             complement(31082..32068)
                     /locus_tag="VQT46_000425"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET2370515.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGLYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            32262..34730
                     /gene="gyrA"
                     /locus_tag="VQT46_000426"
     CDS             32262..34730
                     /gene="gyrA"
                     /locus_tag="VQT46_000426"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET2370516.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            34730..35473
                     /gene="srtA"
                     /locus_tag="VQT46_000427"
     CDS             34730..35473
                     /gene="srtA"
                     /locus_tag="VQT46_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET2370517.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
     gene            35717..36514
                     /locus_tag="VQT46_000428"
     CDS             35717..36514
                     /locus_tag="VQT46_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET2370518.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            36662..36784
                     /locus_tag="VQT46_000429"
     CDS             36662..36784
                     /locus_tag="VQT46_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HET2370519.1"
                     /translation="MTCDFKFETLQLHAGQVVAPATKSRAVPIYQTTSFIFDDT"
     gene            36806..37846
                     /locus_tag="VQT46_000430"
     CDS             36806..37846
                     /locus_tag="VQT46_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HET2370520.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILALAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFVDVDNLEEVEAAIKDNTKLVLIETLG
                     NSLINIPDLEKLAEIAHKHQIPLVSDNTFAIPYLINVFSHGVDIAIHSATKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTCDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKDVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            38017..39291
                     /locus_tag="VQT46_000431"
     CDS             38017..39291
                     /locus_tag="VQT46_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET2370521.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKDFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            39301..40179
                     /gene="truB"
                     /locus_tag="VQT46_000432"
     CDS             39301..40179
                     /gene="truB"
                     /locus_tag="VQT46_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET2370522.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALTLEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            40447..40722
                     /locus_tag="VQT46_000433"
     CDS             40447..40722
                     /locus_tag="VQT46_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET2370523.1"
                     /translation="MEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSVMANLSQGL
                     SLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            40830..41468
                     /gene="udk"
                     /locus_tag="VQT46_000434"
     CDS             40830..41468
                     /gene="udk"
                     /locus_tag="VQT46_000434"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET2370524.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            41596..42936
                     /locus_tag="VQT46_000435"
     CDS             41596..42936
                     /locus_tag="VQT46_000435"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET2370525.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            42914..43126
                     /locus_tag="VQT46_000436"
     CDS             42914..43126
                     /locus_tag="VQT46_000436"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET2370526.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            43123..43998
                     /locus_tag="VQT46_000437"
     CDS             43123..43998
                     /locus_tag="VQT46_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET2370527.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLESLQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            43991..44806
                     /locus_tag="VQT46_000438"
     CDS             43991..44806
                     /locus_tag="VQT46_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET2370528.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHSVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            44799..45230
                     /locus_tag="VQT46_000439"
     CDS             44799..45230
                     /locus_tag="VQT46_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2370529.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            45237..46904
                     /gene="recN"
                     /locus_tag="VQT46_000440"
     CDS             45237..46904
                     /gene="recN"
                     /locus_tag="VQT46_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET2370530.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNKMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            46906..47634
                     /locus_tag="VQT46_000441"
     CDS             46906..47634
                     /locus_tag="VQT46_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET2370531.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYSRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            47713..49536
                     /gene="lepA"
                     /locus_tag="VQT46_000442"
     CDS             47713..49536
                     /gene="lepA"
                     /locus_tag="VQT46_000442"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET2370532.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(49738..49818)
                     /locus_tag="VQT46_000443"
                     /pseudo
     CDS             complement(49738..49818)
                     /locus_tag="VQT46_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
BASE COUNT        15242 a         8948 c        11370 g        14542 t
ORIGIN      
        1 tttacgagtt gtataaagat aaaaattata ataagcaaga atactacaaa agtggtggaa
       61 aaactgtcct agaaacattg agaaagagat ttggtttgaa agactatgtt tccccaacag
      121 aaattgatac tgataagaaa ttcgttttca tcatcgatga aatcaatcgt ggggagattt
      181 ctaagatttt tggcgaactc tttttctcta tcgaccctgg ctatcgtggt gaaaaaggaa
      241 gtgtttctac ccaatatgca aatctacacg aaactgatga aaagttctat atccccgaaa
      301 atgtttacat catcggaact atgaatgata ttgatcgttc agtggatacc tttgattttg
      361 ctatgcgtcg tcgttttcgt tttgttgaag ttactgccga gggtcaagtt ggcatgttgg
      421 ataaagagct gaatatccat gcagaagaag caaaaattcg tctaagaaac ttgaacgctg
      481 ctatcgaaaa tgttcaggaa ttaaacagtc attatcatat tggaccaagt tattttctta
      541 agttgaagga tgtagatttt gactatgaat tactctggtc cgattatatt aagcctctcc
      601 tagaagacta cttgcgaggt tcttatgatg aggttgaaac tttggaaact ttgaaaaaag
      661 catttgaact gacaaataat gagcaaaaag atcaggcagt agctgatgac aatgaaagcg
      721 atgaaaacga tgatgcggat tactgataat caacacaaga ttattaaaga aaaatttgtt
      781 gaagaatatc ctaaactaag caatcttctt ttagacagaa ccttggaaag tctatcccaa
      841 gatgaacgta ttttcatttt tccaaatgat ttgactcata ctccagattt ggataaaaaa
      901 caaaagattt tggaaacgat caatcaggaa atcaagacag gaaatgtgat tggttttctt
      961 ggatatggtc aggaaagatt aacgatttcc tcacgatttt ctgatgagag taatgaccat
     1021 tttttgcatt atctcttaaa caaggttctt catatcaatc tcactagttt agatgttgct
     1081 ttgtctcgtg aagagaggct ttatcaactt ttgatgtatc tcttccccaa gtatctacaa
     1141 gctgctattc gaaaaggtct ttataaggaa tatcatcgat tttctcataa cgacagtcat
     1201 gttaagggag tgattgatgt aagaaaccat ctcaagaaaa atcttccttt cacgggaaat
     1261 attgcctaca caacgagaga gttcacctat gataatcccc tcatgcagtt ggtccgtcac
     1321 actattgaat acattaagaa tcagaaaagc attggtcaag gggtactaga taatctctca
     1381 actagtcgtg aaaacgtatc tgaaatcgtg cgtgtaacgc cctcttataa actagctgat
     1441 cgtgctaaga ttattcgggg aaatcaatct aaacctatac gtcatgcata ctttcacgag
     1501 tacagaaact tacaagaact ttgtctgatg atcctaaacc aagaaaagca cggtttaggg
     1561 tatcaagatc aaaaaatcta tggtattctc tttgatgttg cctggctttg ggaagagtat
     1621 gtttacacct tgttgccaaa aggttttgta catcccagaa ataaggataa gacggatgga
     1681 atttcagtat tttctgttgg gaaacgaaaa gtatatccag atttttatga cagagaacga
     1741 aagattgttc tagatgcaaa atataaaaaa ctggaattga ctgaaaaagg aatcaatcgt
     1801 gaggacttat tccagctgat ttcctattct tatattttaa aagctgagaa ggctggactt
     1861 gtttttccga gcaaggacaa ggttattgat aatgagatgg gaaacctagc aggttatgga
     1921 gctttgttga agaaatggtc tatccaaatt cctcagaagt cttcatctta tagtgcattt
     1981 tgtaaaatga tggaaaattc agattatagt gcattttgta aaatgatgga aaattcagaa
     2041 gaaaatttta aagcgattat tgatgaagaa gtggggagaa aataatttcc cctctttctt
     2101 ttatttttaa cacaagtaaa acccgaacaa tatatttcaa ttcataaaat aatttgacaa
     2161 aaactgtact ttggtttata ataaattaag gaaacgtcgg aaaagacgta gtgatgcgag
     2221 agcataggta ggtcattaca aaagaaacga gacatcgata tgttaaatga atttccaatt
     2281 tttgattacg aagatattca attgattcca aataaatgtg tcattaaaag ccgtgcagaa
     2341 gcggatacaa gtgtcacttt aggaaatcac acctttaaac tacctgttgt gccagcgaat
     2401 atgcagacga ttttggatga aaatgtagca gagcaactgg ctaaaggtgg ttacttctac
     2461 attatgcacc gttttgatga ggcaggacgc attcctttta ttaaacaaat gcacgatcaa
     2521 gggctcattg cttccatctc tgtcggtgtt aaggactatg agtatgattt tgttagccag
     2581 ctcaagactg atgctcctga gtatatcact attgatattg ctcatggtca tgcggatagc
     2641 gtgatttcta tgattcaaca tatcaagaaa gaattgccag atacctttgt cattgctgga
     2701 aatgtgggaa caccagaagc tgtgcgtgaa ttggaaaatg ctggtgcgga tgctactaag
     2761 gtcggaatcg gtcccggtaa ggtttgtatc accaaggtta agactggttt tggtacaggt
     2821 ggttggcagt tggctgctct acgctggtgt gccaaggctg cgcgtaaacc gattatcgct
     2881 gatggaggaa ttcgtactca cggtgatatt gctaagtcta tccgcttcgg tgctagcatg
     2941 atcatgattg gttccctctt tgcaggacac attgaaagtc cagggaaaac gattgaagtc
     3001 gatggtgaac agttcaaaga atattatggt tcagcctcac aatatcaaaa aggtgcttac
     3061 aaaaatgtgg aaggcaaacg tatcttgctt cctgctaaag gtcatctgca agacacttta
     3121 actgagatgg aacaagacct tcaaagtgct atttcttatg caggtggacg tcaggttgct
     3181 gaccttaaac acgttgatta tgtgatcgtg aaaaactcca tctggaatgg ggatgcttcc
     3241 cactaagacg gggtctttga ccaaaaaact tgttattaga gcaaatttct gttataataa
     3301 aacaagtttc cacccttagt gtaatggata tcacgtaaga ttccggttct tgagatgggg
     3361 gttcgattcc ctcagggtgg atgtaaacat cctaaaaagc ctttaatagg gcttttttct
     3421 ttatcctgac ccaaatttgc cgctaaaact gagaatctct gtctaaagaa ttcccaaatg
     3481 ctttccagtc ccgttttaga gtgactcagg gggctttttt tgatataata aaaaggactg
     3541 ttatcagtta gaaagaggtt ggtatgaaag aattacaaac tgtactaaag aatcattttg
     3601 caatcgaatt tgcagacaaa aatttactgg aaactgcctt tactcatacg agttatgcca
     3661 atgagcaccg cctcttaaaa atttcacaca atgaacgctt ggaattttta ggagacgctg
     3721 ttctacagtt attgatttca gaatatctat ataaaaaata tcctaaaaag cctgaaggtg
     3781 acctatcaaa actccgtgct atgattgtcc gtgaggagag tttagctggt tttgcgcgtg
     3841 attgccagtt tgaccagttt atcaagttgg gtaaagggga agaaaaatca ggtggtcgca
     3901 atcgtgacac cattcttggt gatgcctttg aagcctttct tggtgccctt cttttggata
     3961 aggatgtggc caaggtcaag gaatttatct atcaagtcat gattcctaag gttgaagcag
     4021 gcgaatttga gatgattaca gactataaaa cccatctcca agagttactt caggtcaatg
     4081 gtgatgtggc tattcgttat caggtgattt ctgaaacagg gcctgctcac gataaggtct
     4141 ttgatgtaga agttcttgtt gaaggtaaga gcatcggtca aggccaaggt cgttctaaga
     4201 aattagcaga gcaggaagct gccaaaaatg ccgttgagaa ggggctggat tcatgtattt
     4261 aaaggaaatc gaaattcagg ggttcaagtc ttttgctgat aagaccaagg tcgtttttga
     4321 ccaaggtgtg acggcagttg ttggacccaa tggatctgga aagtccaata ttacagaaag
     4381 tctgcgttgg gctttggggg agtctagtgt caagagtctc cgtgggggca agatgccgga
     4441 tgtcatcttt gctggaacag aaagtcgcaa accgctcaat tatgcttctg tagttgtgac
     4501 tctggataat catgacggat ttatcaagga tgcaggtcaa gaaatcaggg tggaacgcca
     4561 tatctatcgt agtggagata gcgaatacaa gattgacggc aagaaagtcc gtctgcgtga
     4621 tattcatgac cttttcttgg atacaggttt gggacgagat tccttctcta ttatttccca
     4681 agggaaggtt gaggagattt ttaattccaa gtctgaggaa cgacgagcta tttttgaaga
     4741 agctgctgga gttttaaaat acaagactcg cagaaaagaa accgagagta aactgcagca
     4801 aactcaggat aatctggacc gcttagagga cattatctac gagttggata atcaaatcaa
     4861 gcctcttgag aagcaagctg agaatgcccg taaatttcta gacttagaag gtcaacgcaa
     4921 ggctatttac ttggatgtat tggttgctca aatcaaggaa aataaggcag aactagagtc
     4981 gacagaagaa gagttggctc aggttcaaga actcttgatg agttattacc aaaagcgtga
     5041 aaaattagaa gaagaaaatc aaactcttaa aaagcaacgc caagatttac aggctgaaat
     5101 ggccaaagac caaggcagtt tgatggactt gactagtctg attagtgatt tagaaagaaa
     5161 attagcccta tcgaaactgg agtctgagca agtggccttg aatcaacagg aggcacaagc
     5221 tcgtttggct gctttggagg ataagagaaa ttcactcagc aaagaaaagt ctgataaaga
     5281 aagctcttta gctctgttag agggaaatct agtccaaaat aatcaaaaac tcaatcgttt
     5341 agaagctgaa ttgctggctt tctcagacga tcctgatcag atgattgagc tcttacgtga
     5401 acgctttgta gctcttttac aagaagaagc ggatgtctca aaccagttga cccgtattga
     5461 gaatgagttg gaaaatagtc gtcagctttc tcaaaaacaa gcagatcaac tagaaaagct
     5521 gaaagagcaa ttagctatag ctaaagagaa ggctagtcag caaaaggaag agcttgaaac
     5581 tgccaaggag caggttcaga aattattggc tgactaccaa gctattgcca aggagcaaga
     5641 ggagcagaaa acttcctatc aagctcaaca aagccaactc tttgaccgtc tggataatct
     5701 caaaaacaag caggccagag ctcaaagttt ggaaaatatc ctgagaaatc atagtaactt
     5761 ttatgcaggt gttaagagtg ttctccaaga aaaagatcgc ctaggtggga ttattggtgc
     5821 agtcagtgag catctgacct ttgatatgca ttatcaaact gccctagaaa ttgcgcttgg
     5881 agcgagtagc caacatatca tcgtagaaga tgaagagtcg gcaaccaagg ctattgactt
     5941 ccttaaacgg aacagagccg gtcgtgcaac ctttcttcct ttgaccacta tcaaggcgcg
     6001 tacgatttct agtcagaacc aagatgctat cactgtaagc ccaggtttcc ttgggatggc
     6061 agatgagttg gtgacttttg atactagact ggaagccatt ttcaagaact tgctagctac
     6121 gacggctatc tttgatgccg tagaacatgc gcgtgcagca gctcgccaag ttcgttatca
     6181 ggttcgtatg gtgacattgg atgggacaga attacgcacg ggtggttcct atgcgggtgg
     6241 tgccaatcgc caaaataaca gtattttcat caagccagaa ctggagcaat tacaaaaaga
     6301 aattgctgca gatgaagcaa gcttgcgttc agaagaagcg gctttgaaga ccttacaaga
     6361 ccagatggct acattgacag aaagattaga agtcatcaaa tctcaaggag aacaggcacg
     6421 tattcaggag caaggcttgt ccctcgctta tcagcaaact agtcagcaag ttgaagaact
     6481 ggaaactctt tggaaactcc aagaagagga aatagatcgt ctttccgagg gagattggca
     6541 agcggataag gaaaaatgcc aagatcgtct tgctgcaatc gccagtgaca agcaaaatct
     6601 ggaagctgag attgaagaga ttaagtctaa caaaaatgcc atccaagaac gctatcaaaa
     6661 cttgcaggaa gagctagcgc aagctcgttt gcttaagaca gaactgcaag ggcaaaaacg
     6721 ttatgaagtt gctgatattg aacgcttagg caaggaattg gacaatcttg attttgaaca
     6781 agaggaaatc cagcgccttc ttcaagaaaa ggttgataat cttgagaagg ttgatacaga
     6841 attgctcagt caacaggcgg aagaagccaa aactcagaaa acaaatctcc aacaaggttt
     6901 gattcgcaag cagtttgagt tggatgatat tgaaggtcaa ctggatgata ttgctagtca
     6961 tttggatcag gctcgccaac agaatgaaga gtggattcgc aagcaaacac gtgctgaagc
     7021 caagaaagaa aaggtcagcg agcgcttgcg ctatttacaa agtcaattaa cagaccaata
     7081 tcagattagc tatactgaag ctctagaaaa ggcgcatgaa ttggaaaacc tcaatctggc
     7141 agagcaagag gtgcaggatt tagagaaagc tattcgctca ctggggcctg tcaatataga
     7201 agctattgac cagtacgaag aagttcacaa tcgtctggat ttcctaaata gccaacgaga
     7261 tgatattttg tcagcgaaaa atctgctcct tgagaccatt acagagatga atgatgaggt
     7321 caaagatcgc tttaaatcaa cctttgaggc cattcgtgaa tcctttaaag tgaccttcaa
     7381 acagatgttt ggaggaggtc aggcagactt aatcttgact gagggagact tgttgacagc
     7441 tggggttgag atttctgttc aacctccagg taagaaaatc cagtcgctta acctcatgag
     7501 tggtggtgaa aaagccttat cagctcttgc tttgcttttt tctatcattc gagttaagac
     7561 tatcccattt gtcatcttgg atgaggtaga ggccgcgctg gacgaagcca atgttaaacg
     7621 ttttggggat tacctcaatc gatttgacaa ggacagccag tttatcgtcg taacccaccg
     7681 taagggaacc atggcagcgg ctgattctat ctatggagtg accatgcaag aatcgggggt
     7741 ctcaaaaatt gtttcggtta agttaaaaga tttagaaagt attgaaggat gacaattaaa
     7801 ctagtagcaa cggatatgga cggaaccttc ctagatggga atggacgctt tgatatggat
     7861 cgtctcaagt ctctcttggc ttcctacaag gaaaaaggga tttactttgc ggtggcttcg
     7921 ggtcggggat ttctgtctct ggaaaaatta tttgctggtg ttcgtgatga cattattttc
     7981 atcgcggaaa atggcagttt ggtagagtat caaggtcagg acttgtatga agcgactatg
     8041 tctcgtgact tttatctggc aacttttgaa aagctgaaaa cgtcacctta tgtagatatc
     8101 aataaactgc tcttgacggg taagaagggt tcatatgttc tagatacggt tgatgagacc
     8161 tatttgaaag tgagtcagca ttataatgaa aatatccaaa aagtagcgag tttggaagat
     8221 atcacagatg acattttcaa atttacaacc aacttcacag aagaaacgct ggaagctgga
     8281 gaaacttggg taaacgataa tgtccctggt gtcaaggcta tgacaactgg ctttgaatct
     8341 attgatattg ttctggacta tgtcgataag ggagtggcta ttgttgaatt agctaaaaaa
     8401 cttggtatca caatggatca ggtcatggct tttggagaca atcttaatga cttacatatg
     8461 atgcaggttg tgggacatcc tgtagctcct gaaaatgcac gacctgaaat tttagaatta
     8521 gcaaagactg tgattggtca ccataaggac cagtcggtta tagcttatat ggagggctta
     8581 taatggcaga tataaaatta atcgcattgg acttggatgg taccttgctg actactgata
     8641 aaaggctgac ggatcgcacc aaggcaactt tgaaagctgc gagtgatcgt ggtatcaagg
     8701 tcgtattgac aactggtcgt cccttaaaag ccatggactt ctttctccat gagttaggga
     8761 ctgacggcca tgaagatgag tataccatta cttttaatgg tggattagtt cagaaaaata
     8821 caggagaaat ccttgataaa acagtctttt catatgatga tgtggcacgt ttgtatgagg
     8881 aaacagagaa attatcactg cctcttgatg ccatctcaga aggaacagtt tatcaaatcc
     8941 aatcggacca agaaagtctt tatgccaaat tcaatccagc tttgactttt gttccagttg
     9001 actttgaaga cctgtctagt caaatgacct acaacaaatg cgtgactgcc tttgctcaag
     9061 aacccttgga tgcagccatt cagaagattt ctccagaatt gtttgaccaa tatgaaatct
     9121 ttaaatcacg tgaaatgttg ctagaatggt caccaaagaa tgttcataaa gcaacaggtt
     9181 tggcaaaact aattagccat cttggaattg atcaaagtca agtgatggcc tgtggtgacg
     9241 aggccaatga cctctctatg attgaatggg cagggctcgg tgttgccatg caaaacgctg
     9301 ttcctgaagt aaaggcagcc gcaaatgtag tgacgccgat gaccaacgat gaggaagctg
     9361 tcgcctgggc tatcgaagaa tatgtgctaa aggagaacta agatatggga ttatttgacc
     9421 gtctattcgg aaaaaaagaa gaacctaaaa tcgaagaagt tgtaaaagaa gctctggaaa
     9481 atcttgattt gtctgaagat gttgatccta ccttcacaga agttgaagaa gtttctcaag
     9541 aagaagctgt gcttgaagaa agtcaggatt cagagccagc tgtaggggtt tctcaagaag
     9601 aaatagaaga attaccagag gaagagaagc ttgagcacga aggaactata gaagaaaata
     9661 attctgaagt tcttgaagca gaaaggcctc aaacagaaga aactgttcag gaaaaatatg
     9721 accgcagtct taagaaaact cgcacaggtt tcggtgcccg cttgaatgcc ttctttgcta
     9781 acttccgctc tgttgacgaa gaatttttcg aggaactgga agaactgttg attatgagtg
     9841 atgttggtgt ccaagtcgct tctaacttaa cggaggaact acgttacgaa gccaagcttg
     9901 aaaatgccaa gaaacctgat gcacttcgtc gtgtcatcat tgagaaattg gttgagcttt
     9961 atgaaaagga tggtagctac gatgaaagca tccacttcca agataacttg acagttatgc
    10021 tctttgttgg tgtgaatggt gttgggaaaa caacttctat cggaaaacta gcccaccgct
    10081 acaaacgagc tggtaagaag gtcatgctgg ttgcagcaga taccttccgt gcgggtgcag
    10141 tagctcagct agctgaatgg ggccgacgag tagatgttcc agtagtaact ggacctgaaa
    10201 aagctgatcc agccagcgtg gtctttgatg gtatggaacg tgccgtggct gaaggtatcg
    10261 atattctcat gattgatact gctggtcgtc tgcaaaataa ggataacctt atgactgagt
    10321 tggaaaagat tggtcgtatt atcaaacgtg ttgtgccaga agcaccacat gaaaccttct
    10381 tggcacttga tgcatcaaca ggtcaaaatg ccctagtaca ggccaaagaa ttttcgaaaa
    10441 tcacaccttt aacgggaatt gttttgacta agattgatgg aactgctcga ggaggtgtgg
    10501 ttctagccat tcgtgaagaa ctcaatattc ctgtaaaatt gattggtttt ggtgaaaaaa
    10561 tcgatgatat tggagagttt aactcagaaa acttcatgaa aggtctcttg gaaggtttaa
    10621 tctaatcaga agcaaaaatc ctgcaaggca taaacttgca ggaaattttt ttattcgaaa
    10681 cgaccatctt gacgataggc gatatctggt tgccaagtcc atttggcacc gaatttttca
    10741 agtaggtcaa agctggcttg aggtcccatg cttccagctt tatagtcatg aagtggggca
    10801 ccattttcag cccagagctc ttcaatacgg tcaatcaact tccatgatgc accaacttca
    10861 tcccagtggc taaagttagt tgagttgtta tttaggacat cataaatcaa tttctcgtat
    10921 ggttctggag aagcaccagt tgcagtcgca tctgtacggt aatcaagtga gttaggagcc
    10981 aagttaaatt cttctcctac ttgcttccca tttaggctaa gagagaagcc ttctgttggt
    11041 tgaatataga tggtcaaaat atttggagca agtggttctc caaagataga atccatttgt
    11101 ttaaagacga tgttgacatg agttcctttt tcagtcagtc gtttacctgt acggaaaaag
    11161 aaaggaacac tacggaatcg atcgctgtct acaaagaagg caccagatgt aaaggtttca
    11221 gttgttgatt ctggattcac atttggctcg ctacgataag agatgtattt catgccatca
    11281 atcttaccag agcggtattg cccacggata aagtgttctt tgagttcttc atcagttgga
    11341 tgatagaggt ttttaaagac cttaatcttt tcagcacgaa tctcgtcttt tgtgaagatt
    11401 gctggtttgt ccatggcgag gagcgaaaga agttgtagag tgtggttttg gaccatgtca
    11461 cggagggcac cggattggtc atagtagcca ccacgttctt ctacacccaa gcgctccgca
    11521 aaggtaattt gaacattgtc gataaaatcc ttgttccaaa cgttttcaaa aatcaagttt
    11581 gcaaagcgaa ctgcaaagat gctttggatc atttccttac caagataatg gtcgatacgg
    11641 aaaatttgtt cttcgtcaaa tgttgctagg agttcgtcat tcaacttgct tgcagttgcg
    11701 taatctgtac caaatggttt ttcaacgatc aagcgctcaa aacctttgcc atcgacaatg
    11761 ttttcagatt tgaggtgttt ggcaatggtt ccaaagaact gaggtgccat agacaagaag
    11821 aagagcttat tgtgttcagc ttggtatttt tcattaagct cagcttgtaa ttgacgcaaa
    11881 gcaatataat gttccgaatc attgacatca tggctttgat agtagaagtg gctagcaaat
    11941 tcttgggctt gctcggtact atctgccaaa tcaaggatgg actcgacaac tacagattca
    12001 aaatattcct tactccaagg tctacgggca gttccaataa cggcaaagtg cttggaaaga
    12061 ttgccggatt gatatagtct aaaaagggaa gggtagagct tgcgtttagc caggtctcca
    12121 ctcgcaccga aaattgtaac aataacctta gatgacatct agctacctaa tttctatttt
    12181 tattcctagt cttgctaggt atgaggaaac ctcatttcat aaacttaatt ctaacataat
    12241 tttccgaaaa atcaaaaatt ccaatacgag gtagaaaaac tgcaaggaaa tccttacagt
    12301 ttgagtttag acgtttaaga ccttatctaa gaactctttc agacgagggt gttgtgggtt
    12361 atcaaagatt tggtcaggtg ttccgtcttc aaggaactcg ccatctgcag taaagataac
    12421 gcggttggca acctgacgag caaatcccat ctcatgggtt acgataatca tggtcatgcc
    12481 ttgctcagcc aattccttca taacgttaag tacgtctcca accatctcag ggtcaagggc
    12541 agaagttggt tcatcgaaga gcatgatgtc tggattcatt gctaggccac gagcgatggc
    12601 cacacgttgt ttttgaccac ctgataggtt atctggattg gcattagctt tatctgctag
    12661 tccaaccttt tcaagcaact ccattcccaa ttcctcagct tcttccttag tcatcaactt
    12721 gtgctcaata ggagcaaagg tgatgttgtc caatacagac atatgaggga agaggttgaa
    12781 gtgttggaat accatgccga tattttcacg gacgtggtca acattggttg ttttttcagt
    12841 taaatcatag ccgttcacag tgatgtgacc gctagtgact tcttctaaaa gattgaggct
    12901 acggaggaaa gttgacttac cagaacctga aggaccgatg atacaaacaa catctccttc
    12961 atagaactta gtcgtaattc cttttaggac ttcatttttt ccatagtgct tgtgtaaatc
    13021 atttacatca atttttaatt ttgccattaa cgaatcctct tttctaagcg tttcgctagt
    13081 ctagtcaaaa gtgtgataat tacaagatag aagatagcaa ggattgcata catcttgaaa
    13141 ctttggtagt tacgagcaat gataatctta ccagtttgga agagttcaac caaaccgata
    13201 gcagatacga tagttgtatc tttaagagcg ataacgaatt ggttgacaaa gtttggcaac
    13261 atcaatttag ttgcttgtgg caagataatc ttacgcatgg tttttccata agagataccc
    13321 aagcttcggc tggcttccat ttggccaact ggaacggcct gaataccacc acgaacgatt
    13381 tcagcgatat aagcagccgc attgagtgag agggcaatgg ttccagctac aaagtcgtta
    13441 attgggcttt gttggcctgt gatagactcg atgaagtttg gaattcccca gaagatgaag
    13501 gctgcaagaa tcatcaatgg aataccacga ataacgtcaa cgaaaatctc agagatgacg
    13561 cgaagagatt tgtatgggct aacgctaaac ataccgaaga taattccgat gacaatggca
    13621 atagcaaatg agataagagc tagagcaaga gtgataccaa gaccgctaag gagttgtttg
    13681 tagttgtttt gaagcaagcc ccagagcgtt gtttcgtcaa cagtacttgt tgaagcagtt
    13741 gaagattcgc tagctaggta tttgtcaaga atcttttgga attcaccgtt tgctttaagg
    13801 tttgcaagtc cgttgttgaa catttcaatc agttctggat ttgctccttt tttaacggca
    13861 aaggctgttt caccgattgg agttccagag attggagttt tcaatttttg accttggctg
    13921 atagaatatt tgagaacagg ttcatcatcc ataacggcat caatggcacc agtgtttaaa
    13981 ctgtcataca ttgaagaacc atcagcaaag gttttgattt tgtaaccgta tttgctttga
    14041 ttttctgtta ggaaggtttg agaagcagtt ccgtttttaa caccgactgt ctttcctttt
    14101 agatcttcat aagaagcaat attgcttgat tctttgacac caagaatggt attagcagtg
    14161 tagtatgatt ctgagaagtc aaaagttgcc ttacgagcat ctgtgacaga cataccagca
    14221 atgataccat cggcttgacc agcttggaca gcactgatag cagcatcaaa accagggttg
    14281 gtgatttcaa tttcaaaacc ttggtcttta gcgattgcct taatcaattc catatcaata
    14341 ccagtgtatt ggttgcttga attttggaaa acaaaaggtg caaaagaaga atcgctggca
    14401 atgatatatt tagccttaac aggaatagct tttaatcctg cgagagtagt tgtagttggc
    14461 actgctgaag atgatgaagc agtccatttc ttgataattt tatcaagact accatctttt
    14521 ttcatttcag ccaaggcttg gttaaattca gtaaccaggt gctcgtattt acttcctttt
    14581 ttcacaccga aagcaaaact tcctacagct tcaccatcca tttcaatatg gaggtcttga
    14641 ccttggttaa tggcatattc gataacaggt ttgtcatcca tcatggcatc gatggcacca
    14701 gcactcaagc tgttgttcat taaatcacca gtgtcaaatg ttttaatagt aaagccgtat
    14761 ttatctttga ttgtttcaag gaaacgttga gcggcagttc cgtttttaac accaacggtt
    14821 ttgccagtta attggtcgta cttgctaatt ttgtgtgact ttgtagtagc aatgacaact
    14881 tttgtatcat agtaagtatc agacatggtg aagacttttt cacgttcttt agtctttgtc
    14941 atccctgcca tgatagcgtc ggcttgccca gcttgaaccg cattgactgc tgcgtcaaat
    15001 ccaggatagg acatctgaat gttccagcct ttaatctcag cgactttgtt aataatgtca
    15061 acatcaattc ctttataagt ttgatctgaa tctttaaact caaaaggtgc ataggcggta
    15121 tcagaaacaa tcttaatcgt ttctgctttg gcaataccta atgagaaaat tgggaataaa
    15181 attagcaaaa atgctagaaa ttttttcttc atttttagtc tccttttccg aatattctct
    15241 cattatatca gaaaaagtaa aaaaaggcaa atttttatat ttttcgtgtc agaaaatata
    15301 acattgattt ttccttttct ttcttgaatt gctattaaaa attgctataa taatactata
    15361 tatagaagaa aagaggacgg ggatatgaag aacaaaagaa tatttaaaga cttccaagct
    15421 tcaaaaatga atttaaacct ttacacaagc cccttgttag cctttgtttt tgtcttcata
    15481 ggagagtttg tggcttatac tttatatggt attagtttgt tagctctcat cggacttgct
    15541 agaaattttg gagaggctgg tcaaaatctt gcaagctact tgcagacctt gcatcagagc
    15601 ttgacggata aaacaagtga ctttcgttta attttaggat tactggcctt tggttttatt
    15661 cttaacactg tgttcagatg gacaagaaaa gttgagaaaa gacctattcg aaccttggga
    15721 ttttatagag agaattgcct cagcaatctt ctgaaaggat ttagtctagg cctggcactt
    15781 tttcttctga ccttgttaag tttagtggtc ttaggtcaat atcgtttgga atccattcac
    15841 ttgaatcctt attatcttgc ctttgtcgtc tttactatcc cattttggat tttacagggg
    15901 acagcagaag aagtggtggc ccgtgcttgg ctacttcctc aattggcctc aagaaccaat
    15961 ctaaaactag ctattcttat atctagcctg ttctttaccc tgcttcatat gggcaattct
    16021 ggcctcaccc ctctatctct agtaaatctc tttttattcg gagttgccat ggctctttac
    16081 cttctcaaaa ctgatacagt ttggggtgtt gcaggtattc atggtgcttg gaattttgct
    16141 cagggtaatc tctttgggat tttagttagt ggtcaaccgt caggaacgtc tctgatgacc
    16201 tttttaccac aaggcaatca agattggcta tcaggtggtt cttttggcat agaaggttcc
    16261 attatgacaa gtctggtatt actactgctg attgtctatc ttgctaataa attaaagaaa
    16321 gaaaatgaaa ggatgtgact tcggtccgtc cttttcttcg tgaaaatact ataagtatgc
    16381 taaaatagga atagcacatg gagagaggat tcttatgatc aatcacatta cagataatca
    16441 atttaaacta gtatcaaaat atcaaccatc aggagatcaa ccccaagcta tcgagcagtt
    16501 ggtggataac attgaggggg gagaaaaagc tcagattctg atgggggcga ctggaacagg
    16561 gaagacctat actatgagtc aggtcatttc taaagtcaat aaaccaactc tggttattgc
    16621 ccacaataaa actctggctg gtcagctcta tggggagttt aaggaatttt tccctgaaaa
    16681 tgcagttgag tatttcgtat cctactatga ttattaccag ccagaggcct atgtcccttc
    16741 tagcgatacc tatattgaga aggatagttc tgtcaatgac gagattgaca agcttcgcca
    16801 ctcagctacc tcagcccttt tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg
    16861 tatctatggt ttgggttcgc ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg
    16921 tctagagatt tctcgtgata aactcttgaa tgacttggtc gatattcagt ttgaacgcaa
    16981 tgatattgat ttccaacgcg gaagatttcg cgttcgtggg gatgtggtag agattttccc
    17041 agcttcccga gatgaacatg cctttcgagt agaatttttt ggagacgaaa ttgaccgtat
    17101 tcgtgaagtt gaggctctga caggtcaggt gttgggagaa gtggatcatt tagcgatttt
    17161 cccagcgaca cactttgtga ccaatgacga ccacatggaa gttgccattg caaagattca
    17221 ggccgagttg gaagaacaat tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca
    17281 gcgtttgaaa cagcggacag agtatgatat cgaaatgttg cgtgagatgg gctataccaa
    17341 tggggttgaa aattattctc gccacatgga tggacggagc gaaggagagc ctccttatac
    17401 gcttctcgac ttcttcccag atgatttctt gattatgatt gacgagagtc atatgaccat
    17461 agggcaaatc aagggcatgt acaatggaga ccgttcgcgt aaagaaatgc tggttaatta
    17521 tggtttccgt ttgccgtctg ctttggacaa tcgtcctctc cgtcgggagg agtttgagag
    17581 tcacgttcat cagattgttt acgtttcagc gacacctggt gactatgaaa atgaacagac
    17641 cgagacagtg attgagcaaa tcattcgtcc aacgggactc ttggatccag aggtggaagt
    17701 ccgtccgact atgggacaga ttgatgacct cttgggtgaa atcaatgccc gcgttgaaaa
    17761 aaatgagcgt acctttatca caactttgac caagaaaatg gcagaggact tgaccgacta
    17821 cttcaaggaa atgggtatca aggttaagta catgcactcg gatatcaaga ccttggaacg
    17881 gacggagatt atccgtgacc tgcgcttggg tgtctttgat gtcttggtcg gaattaacct
    17941 gctccgtgaa ggaattgacg ttcctgaagt gagcctcgta gctattctcg atgctgacaa
    18001 ggaaggtttc cttcgcaacg aacgtggact catccagact attggacgtg ctgctcgtaa
    18061 cagtgaaggc catgtcatca tgtatgcaga cacggttacc cagtctatgc aacgtgctat
    18121 cgatgaaact gcccgccgtc ggaaaattca gatggcctat aatgaagagc atggtatcgt
    18181 accacagaca atcaagaaag aaatccgtga cctgattgct gtgaccaagg cagttgctaa
    18241 ggaagaggac aaggaagtcg acatcaatag cctcaacaaa caagagcgca aagaactcgt
    18301 caagaaacta gaaaaacaaa tgcaagaagc cgtcgaagta cttgactttg aactggcggc
    18361 tcagatccgt gatatgatgt tggaagtcaa ggccttggat taggggaata gtatgattta
    18421 tttaagaaag ttaaagagag aagatttgat gtctttatgg gaaatggctt attcacaact
    18481 taatccagtt tggaaacagt atgatgctcc ctattatgat gattatcagt atttttcaaa
    18541 ttttaaagaa ttcgaactac aaaaatcaga atccatttta agcaactcaa atcgccttgg
    18601 tatttttgtt gatgataaac tagttgggac tgtttcgcgt tattgggtat gtaaacaaac
    18661 aagatggatg gaattgggaa ttggtattta tgataaaaaa ttctggaaca ctggtattgg
    18721 gaaagttgct atgttgcagt ggatagatag gacgtttcag gattacttgg agttggagca
    18781 tctgggtttg acaacttggt cagggaatct tggtatgatg aaacttgctg aaaaattaag
    18841 aatgaaaaaa gaagctcata ttccaaaagt tcgttattat caaggtaaat attttgatag
    18901 tattaaatat ggtattttga gagaagactg ggagaaaaca aatgacggtt attatcaaat
    18961 caatggaaac tcctgaagag atagaaggta agccccttgt tcactggcaa acgtggagag
    19021 aggcttatga tggccttttg cctgcagaat ttcaggagac aatgacatta gaaagatgtc
    19081 gattctttag tcaaaagtat ccagaaaata cattgattgc gatggatggt atgaaggtag
    19141 ttggttttat cagttatggc aactttcgtg atgagactat tcaagctggc gaaattattg
    19201 ctttatatgt tttaaaagac tattatggaa aaggtatcgc acaaaagtta ataaaagcag
    19261 ctttgattgc tcttaatcat ttttctgaaa ttttcttatg ggtattgaaa gataataagc
    19321 gcgcaattgc tttctatcaa aaaatgggct ttacttttga tgaacaagaa aagatacttg
    19381 aacttggaaa gcccataaag gaaaaacgga tggtattcta ttctaaataa ttttaaaaag
    19441 tagaagctaa tggtactggt atcaagtcta aaaatttaat aaattagaaa gtgagtaaat
    19501 ttatgtctcg agcacaatta acgattttaa caaatatttg tctgattgaa gatctcgaag
    19561 ctcagcgcgt ggtgatgcag tatcgcgctc ctgaaactaa tcgctggtct ggttatgcct
    19621 ttccaggagg ccatgtagaa aatggcgaat ctttcgcaga gtctgtcatt cgtgaaatct
    19681 atgaagaaac agggttgact atccaaaatc ctcaacttgt cggcattaaa aattggccac
    19741 tagatacagg tgggcgctat attgtcgttt gttataaggc aactgagttc tctggtaccc
    19801 ttcgctcttc agatgaagga gaagtttctt gggtgcaaaa agaccagatt ccaaacttgg
    19861 atctggccta tgatatgcta cctttgatgg agatgatgga agcatcggac aaatctgaat
    19921 ttttctaccc tcgccgtaca gaagacgatt gggaaaagaa aattttctaa tcctttacta
    19981 aataacctag ctgatccaag gcctcctcga tatagtggag gtcttgttgt gtttcggctt
    20041 cgactaggtg gtaatggaca ccatctgtca attcagataa aggtttaaaa tcagaatgct
    20101 cgacttgttc tagaaaatgt tgaacgtctc ggcggcaaga cagtttaagc aaggtttcaa
    20161 tttctccata aacgggatgg tcaatcaaag tattctggac atgcccacca ttatcgacaa
    20221 tagcaaggag ttcctgaccg atttcttcaa cttcatgttt cactttgaaa agtttgtgaa
    20281 cataaggatt ggtatcaatt tgcttataga tgtagccacg attggtggat aggataggag
    20341 cgccatcggc tctcaaaatt gcaatgtcct gcacaatgac ctgacgtgtg acatgaaaat
    20401 gttccgccaa actttggcca ttaagggctt taggagcttc tttcaagagt tggagcaggg
    20461 cttgtttgcg atcttttgtc atagcttttc cttttaacgg cgttttcgaa gcactttata
    20521 gacagctagt gctaatgtat agtctaccat actatggata attgtgccaa atccaactag
    20581 tacaaataga acatagaaca tgttttctac attggtaccc gaagttgcgt aaaaaaggac
    20641 acaggctaat acttcagcaa gggcatgaac aacagccaaa acaaaattga aaacccagga
    20701 agattttggt ttatctaggg tatcggggaa tttttgtagg taaagagatc ctaaagcacc
    20761 aaaagatata tgggaaaaag cccgaaaaac tataaccatg ggatagccag ccatcaaaaa
    20821 tccaaaacta gaggctagga tgacaaaaac tgccatcaag ggcgacaaga acatggctat
    20881 aaaaatagcg atgtggctcc ccaaagtata ggaagcaggt ggaatgacaa tcttgaaagg
    20941 cataacaatt ggaatcaaaa tcgcaatagc cgttaaaagg gctgtcattg tcataaattg
    21001 tgtctttttc cgtgtattca caagaatctc ctttttaact gcatatacac tagtatggta
    21061 caataaacca gacaataaag caagaattta cttgggttta tagatcattt tttagttaaa
    21121 agttatagta gatggaaact agaatagtcc acctctactt ctaaaacatt gttagcgatt
    21181 tgactgtcct gatcgatttg tcctgttctt atttcgtttt actatagtaa agatttcatt
    21241 aaaaagaaac tgtatagagc aaaatctcca ccttcaggtt tgaaagcgga gattgttttt
    21301 attttttcaa ggtttgtagt cgtggaacaa tggctagggt tagaattgca gaaatgacca
    21361 attcagcaat tgaatttgtt gagataacgg ttgccagaag aagttggata tttccattat
    21421 aaacatttcc aaataggaag aagattcctc caaggacaaa gatagtattt gtcaaggaac
    21481 caagggctcc agctaaaatc agaccagtct tgtttttcat cagtttatag actaagtaag
    21541 gagttaaacc aatcaaaata cgtgggacga tggcaatgat agctgagtag atgtttccgt
    21601 ttggtacgaa gggagagaag aggtagcttg tcggtagaat cgtaatcgtg ttaaccgtca
    21661 agctaagtaa tcccatcaaa aatccaagtg taaccccaac tcgtggacca taaataatgc
    21721 tggcaataat gacaggaata tgaacaatgg tcggtttgat tggaaatgga aaaaggttaa
    21781 agataagtga gctcagaaag tgtatcacga gcatggtagc aaaaaagata gcaatgggtg
    21841 caatattaga gcgttttttc atcgatagtt tcctttattc tttctaaaat aattgtgagg
    21901 tcagctaaag ctcctcgtcc gtggtctcca caagctagta gggattcctt aggagcaatc
    21961 agctgatagc cgtaggtttc taatgttttc agattattct gagttactgg atggtcatac
    22021 atttttgtat tcatagcagg agctattagt ttgggaatat gacttggtag ggctagagct
    22081 gtactggtta ccatgttgtc cgcaaatccg tgagctagtt ttgcaatagt gttagcagtt
    22141 gcaggtacca cgataaataa atctgctttt tttccaagtt cgatatgatt gacctgatca
    22201 ggatagggtt ccttcatgac atccaagtgg acaggattct gtgagagtac ctgtagtgtc
    22261 aaaggttgga taaactctgt agcagcctga gtcattaaga cagtgacttg atggccttgt
    22321 ttttttagag aactgactaa atctgccgac ttataagagg cgattgaacc cgttacagcc
    22381 aagagaatgt ttgccatagt tttcctttct aagaatgata ggcttgaatt ttttcaagga
    22441 ggagttctgc aatttcttct ttagtctgga ctgtttgaag ctgatttttc tcaacaaata
    22501 tagctcggtg ctgatctgct gaaatttgag tcaggtcatt cgcgatgatt aaatctgctt
    22561 gattcttgat aagacttttt cgtgcaatgt caaccagatg atcttcggta acatcaacca
    22621 gcagtttgaa accaatcaga tgaatagtgg gattccattc cttgactagg gatatgattt
    22681 tgggtgtctt tttaaggaac aaaacctgaa cctcatcagt tgaagaaatc ttggcctgat
    22741 gattctgctt gcttaaaaat tcttttagat tggagctagc ctgaacttcc tcaagccctg
    22801 tcatataaac aggagtgtag tcagaaacag ccattgagtg gatcaagacc tgataatcct
    22861 gaacacgttc ttgcatttct attagaaggt ccttggtatt ggtaatttct cgaatactta
    22921 ggttaggatg aggctctggc ttcagagctc gttttgtcgt aattaaacaa acttcatgcc
    22981 ctgcagaaag caaagtctct gtgataattt tccccaagtg acctgtagaa tggttagtga
    23041 tagagcggac gctatcgata gcttcactgg taccgcccga tgtaactaaa attttcatag
    23101 cactattgta cacaaaaata agcggtaagt aaaatgaaag tgataaattt ttggtaaaaa
    23161 cgaagattta ctatagtttc aaactataaa gccatataaa atttaagaaa ggactctaaa
    23221 agccttaaaa acagagatat ttacgaacgt ttagagagtt ttaggatgtt aaaaatcttg
    23281 ttttgtgata taatgaatta tcatataaga ggttagagga attttgaatg aaaacagata
    23341 ttgaaatcgc acagagtatt gagttgaagc caattgttga tgttgtagag aaacttggta
    23401 tttcttatga cgatttggag ttgtacggaa agtacaaggc taaactcagc tttgataaaa
    23461 ttcgtgcagt tgagagcaat ccagtcggta aattgatctt ggttactgcc atcaacccaa
    23521 cacctgcagg tgaaggaaag tcgacgctta ccattggtct tgcggatgcc ttgaacaaga
    23581 ttggcaagaa aaccatgatt gctatccgcg aaccgtctct tggtccagtc atggggatca
    23641 agggtggtgc tgctggtggt gggtatgcac aagttctgcc aatggaagac atcaacctcc
    23701 actttactgg agatatgcat gctattacaa ctgccaacaa tgccctttct gccttgattg
    23761 acaaccactt gcaccaaggg aatgagctgg aaattgatca acgtcgtatc ctctggaaac
    23821 gcgttgtgga cttgaacgac cgtgcgctcc gccatgtgac tgttggtctt ggtggtcctc
    23881 taaacggtat tccacgtgag gatggttttg atattacagt tgcttcagaa atcatggcaa
    23941 ttctttgctt ggcaacggac atcgaggact tgaaacgtcg tttggcgaat atcgttattg
    24001 gttatcgcta tgaccgtacg cctgtttctg taggtgattt gcaggttgag ggtgccttgg
    24061 ctttgatttt gaaggatgct attaagccaa acttggttca gacaatttac ggtacacctg
    24121 cctttgtaca cggtggtcca tttgccaata tcgctcatgg ctgtaactct gttttggcga
    24181 cgacaacagc ccttcacttg gctgattaca ctgttactga agctggtttt ggtgcggacc
    24241 ttggtgctga gaaattcctt gatatcaaga caccaaactt gccaacatct ccagatgcag
    24301 ttgtcattgt cgcaaccctt cgtgccctta agatgaatgg tggtgtggct aaagacgctc
    24361 tgactgaaga aaatgtagag gcagttcgtg caggttttgc taacttgaaa cgccacgttg
    24421 aaaatatccg taagttcggt attccagcag ttgtagctat taacgaattt gtatctgata
    24481 cagaagctga aattgcagtc ttaaaagaac tctgtgcctc aatcgatgta ccagttgaat
    24541 tggctagtgt ctgggctgat ggagcagaag gtggagtagc acttgccgaa acagttgtta
    24601 agacaattgc tgaaaatcca gctaactata aacgtttgta cgataatgcc ctttctgtcc
    24661 aagaaaagat tgaaaaaatt gtcactgaaa tctatcgtgg tagcaaagtg aactttgaga
    24721 agaaagctca aacacaaatt gctcaaatcg ttcaaaacgg ttgggacaaa ttgccaatct
    24781 gtatggctaa aactcaatac agtttctcag acaatccaaa tgcgcttgga gcaccagaaa
    24841 actttgaaat taccattcgt gaattggtac caaaattagg tgcaggcttc atcgttgcct
    24901 taactggtga tgttatgacc atgccaggtc ttccaaaacg tccagcagct ctcaacatgg
    24961 atgttgaaag cgatggaact gtactaggct tgttctagtg gattgaaatt gactttaagt
    25021 gagtttggaa ataatatcca agctcatttt ttctcagact gcaagcagtt catcaataag
    25081 atttatactc ttcgaaaatc tcttcaaact acgtcagctt caccttgccg taggtatatg
    25141 atactgactc tgtcagttct atccacaacc tcaaaacagt gttttgagca acctgcggct
    25201 agcttcctag tttgctcttt gattttcatt gagtataagt agatagaaaa gttatatact
    25261 atctattgaa aatattataa atcagataca aagacaggtg aaaccttctg tgttatacta
    25321 gagatatgtt agatttgaaa gaatacggta tcgtcatgtg gccggaggag aaagtcattt
    25381 ctttccgtga gaaacttctc gcttggtatg atgaaaacaa aagagatttg ccttggagga
    25441 gaagtaaaaa tccttatcac atctgggtat ctgaaatcat gcttcagcag accagggtgg
    25501 atacagttat cccttactac gaaagattcc tggactggtt tccaactgtc gaaagtctgg
    25561 caactgcgcc tgaggagagt ttactgaaag cttgggaggg cttgggctat tattctcgag
    25621 ttcgcaatat gcaggctgca gcccagcaga ttatgactga ctttggtggc caatttccaa
    25681 atacctatga aggaatttcc agcttgaaag ggattggacc ttacacagca ggagccattt
    25741 ccagtattgc ttttaacttg cctgagccag ctgtagatgg taatgtcatg cgggtcttgg
    25801 cgcgtctgtt tgaagtcaac cacgatattg ggattccaag taatcgaaaa atttttcagg
    25861 caatgatgga gatcttgatt aatccggatc gtccgggtga ttttaatcaa gccttgatgg
    25921 acttagggtc tgatattgag tctcctgtaa atcccagacc tgaagaaagc ccagtcaagg
    25981 actttagtgc ggcatatcag aatggaacca tggaccgtta tccaattaaa tctcctaaga
    26041 aaaagccggt tcctatttat cttaaagcat tagttgtgaa aaattctcaa ggacaatttt
    26101 tacttgaaaa aaatgaaagc gaaaagctct tggcaggttt ttggcatttc ccccttatag
    26161 aagttgataa cttttcgcaa gaagagcagt ttgacctctt tcatcaggtt gcggaagaaa
    26221 gtgtgaactt tggccccagt ccagaagaga gtttccagca ggactatgac ctagatgttg
    26281 attggcttga tgtttgtttt gatacagtcc agcatgtttt tagtcatcga aaatggcatg
    26341 tacagattgt agcaggtcag gtgagtgact tccatgattt ttcagatagg gaagttcgtt
    26401 ggctttcacc agaagaattc aagaattacc cacttgccaa accccaacaa aaaatctggc
    26461 aggcttatgc acaagccaac ttagacagta gccaagacta gctattgtgt cttctgacta
    26521 ttttttggta taatagtaga gaaaaaggtg aacatatgaa aaaaatacta attgtagatg
    26581 atgagaaacc aatctcggat attatcaagt ttaatatgac caaggaaggt tacgaagttg
    26641 taactgcttt taatggtcgt gaagcgctag agcaatttga agcagagcaa ccagatatta
    26701 ttattctgga tttgatgctt ccagaaattg atggtttaga agttgctaag accattcgta
    26761 agacaagcag tgtgcccatt cttatgcttt cagccaaaga tagtgaattt gataaggtta
    26821 tcggtttgga acttggggca gatgactatg taacgaaacc cttctccaat cgtgagttgc
    26881 aggcgcgtgt taaagctctt ctgcgtcgtt ctcaacctat gccagtagat ggtcaggaag
    26941 cagatagtaa acctcaacct atccaaattg gggatttaga aattgttcca gacgcctacg
    27001 tggctaaaaa atatggcgaa gaactagact taacccatcg tgaatttgag cttttgtatc
    27061 atttagcatc gcatacaggt caagtcatca cgcgcgaaca cttgcttgag actgtctggg
    27121 gttatgacta ttttggtgat gtccgtacag ttgatgtgac tgtacgacgt ctgcgtgaga
    27181 agattgaaga tacgcccagc cgaccagagt atatcttgac gcgccgtggt gtagggtatt
    27241 acatgagaaa taatgcttga tttactgaaa caaaccattt ttaccagaga ttttatcttt
    27301 atcctgattt tgttaggttt catccttgtt gtgaccctct tattactgga aaatagacgt
    27361 gataatattc agttgaagca aatcaatcaa aaggttaaag atttgattgc aggagattat
    27421 tccaaggttc ttgatatgca aggtgggtct gaaatcacca atattaccaa taatttgaat
    27481 gacttgtcgg aggttattcg tctcactcag gaaaatctag aacaagagag taagaggcta
    27541 aatagtattc tgttttatat gacagatggg gttcttgcga ccaaccgtcg gggtcagatt
    27601 atcatgatta acgatacagc caagaagcaa ctggggttgg ttaaggaaga tgttctgaat
    27661 agaagcattt tggaattgct caagatagaa gaaaactatg aattgcgtga tttgattacc
    27721 caaagtccag aattgttgct agattcccaa gatatcaatg gcgaatattt gaaccttcga
    27781 gttcgctttg ccttgatacg tcgagagtct ggctttattt caggtttggt ggctgttttg
    27841 catgatacga cggagcagga gaaggaagaa cgcgaacgaa gactctttgt ttccaatgtt
    27901 agccatgagt tacggactcc tctgactagc gtaaaatcct atcttgaagc cttggatgag
    27961 ggggctttgt gtgaaactgt agcaccagac tttatcaagg tttctcttga tgagaccaac
    28021 cgtatgatgc gcatggtgac ggatctcctc catctttcac gtattgataa tgctaccagt
    28081 cacctagatg tggaactgat taacttcact gcttttatta cctttatcct caatcgtttt
    28141 gacaagatga aaggacagga aaaggagaaa aaatatgagt tggtgagaga ttatcccatc
    28201 aattctatct ggatggaaat tgatacagat aagatgacgc aggttgtcga caatatttta
    28261 aataatgcta ttaagtattc gccagatggg ggtaaaatca ctgtcagaat gaagacaact
    28321 gaagaccaga tgattttatc catttctgac cacggtttgg ggattcctaa gcaggattta
    28381 ccacgtatct ttgaccgttt ctatcgtgtg gatcgtgcta gaagtcgtgc acaaggtggt
    28441 acaggtctag gactgtctat cgctaaagaa attatcaaac aacataaggg ctttatttgg
    28501 gccaagagtg aatacggcaa gggttcaacc tttaccattg tgctccctta tgataaggat
    28561 gcagtgaaag aagaagtatg ggaggatgaa gtagaagact agaatgagtg aaataggctt
    28621 taaatacagt attttagcgt cgggttccag tggaaattct ttttatctgg aaacctcaaa
    28681 aaagaagctt ttagtagatg caggcttgtc tggcaagaaa attaccagtc tgctagctga
    28741 aattaaccgt aagccagaag acctggatgc catcttgatt acccatgagc attcagatca
    28801 tatccatgga gtaggcgttt tggctcgcaa gtatggtatg gatctttatg ccaatgaaaa
    28861 gacctggcaa gctatggaaa atagtaaata tcttggcaag gtggattctt cgcaaaagca
    28921 tatttttgaa atgggtaaaa ccaaaacctt tggagatatc gacatcgaga gttttggtgt
    28981 aagccatgat gcagtcgcac cgcagttcta tcgctttatg aaggatgata agagttttgt
    29041 cctcttgaca gatacaggtt atgtcagtga ccgtatggcg ggcattgtcg aaaatgcgga
    29101 tggttatctt atcgaggcca accatgatgt agagattttg cgatcaggtt cttacgcttg
    29161 gcgcctcaaa caacgaatcc tatctgacct tggtcacctt tctaacgagg acggtgctga
    29221 agctatgatt cggacgctag gaaatcgtac taagaagatt taccttgggc atttatctaa
    29281 ggaaaacaat atcaaggaac tggctcatat gaccatggtc aatcagctgg ctcaagctga
    29341 tctgggagtc ggagtagact ttaaggttta tgatacctca ccagataccg caacaccatt
    29401 gacagagata tagaaagaac gctgagaagg tgttcttttt atattgactg gacacctaaa
    29461 aagtaataca atggtgttac cattaaaaaa gggagcacaa aagatgacta ctattacatt
    29521 aaaagtttct gaagctgata aaacatttat gaaagcaatg gctaagtttg aaggagtttc
    29581 cctttcggaa cttattcgca ccaaaactct tgaagcccta gaagatgaat acgatgctcg
    29641 tgtggcagat ttagcctatc aagagtattt agaagacttg gaaaaaggag ttgaacccat
    29701 tacttgggaa gaaatgatgc atgatttagg cttgaaggat gaataatttg tataaattag
    29761 ttccaacaag acgttttatc aagcaattga aaaaattgga ccgttatacg cagaagctaa
    29821 ttacaaacta tttacaaacc aatgttttgg aagatccaag acgacacgga aaggctttgg
    29881 ttggtaatcg cgttggtcaa tggcgctata gaattggtaa ttatcgagtt atcgtacaaa
    29941 ttgtagatga tgaattagtt gttgctactc tagaagttgg tcatcggaga gatatttatt
    30001 aaattaaagc tgagtaataa cagtatagaa agtaaggaga gtaaaaattt gaagaaaaaa
    30061 tggttttttg cagattatta tgacacaaca attattttac ttgctttaat ctctgttatt
    30121 ctggtattac ttggatttgc tgagatgatt gatttggaca atccgcctta tagtattatt
    30181 gatttagtaa tctggggtgt ttttgtaatt gattatagtt ggcgcttttt tacgactaaa
    30241 agaaaatggc gctttattct tgaaaatatt tttgatttat tggctattct ccctttaaat
    30301 gctattttta cagtgtttcg attagggcgt atctttcgtt tagctaaact aacaaaatta
    30361 ctgaaactga ctcgtttact tagaataatt ggacttacag gtaaattaga aagaaaaatt
    30421 agtagattct tacggacaaa tggcctgatt tatatcttgt atgttaatat ctttattgtt
    30481 ctagtaggga gttcgatttt atccgttgtt gaagaaaaat ccttctcaga tagtctttgg
    30541 tgggctcttg tgacagtaac tactgttgga tatggggata ttgttcctgc ttccattttt
    30601 gggaaatggc tagcagtttt actgatgctt gtcggtattg gaacaatagg gatgttaaca
    30661 agtgctttga cgaacttttt tgtaaaggat aatccagatg aacagataaa acttgataaa
    30721 ctcaaagatg aattatcgag ccaaagaata ttactagaga aacaatctaa aaagatagaa
    30781 gaactacata aaatgataca agatttgatt gaaaaaacat aataaaaata aagatgagac
    30841 aaagtttgag ctgaggagaa atcaagtaag ttttgacaca atagaacgca tattatcagg
    30901 tataaaaact tgatactatg cgttttatag agaaataaaa taaaatctga acaaatcaat
    30961 taggaattta aagcatttta taacaacgtt ttagagtgat ggggtgctat ttcaacttca
    31021 acctactata atacagaaaa aaacaactcc ctgatgattc aaggagttgt ctatagttaa
    31081 attagttttt agaagcttct tggaattctg gatttttcca tgcttcgtca ataatagctt
    31141 gcaattcttt agcagatgct tgcatttttt gagtttctgc atcgttcaat ggaatgttta
    31201 ctggacgaac gataccatgt gcaccaacaa cagctggttg accgataaag acattctcaa
    31261 ctccgtatag accttcttgg aatactgaaa gtggaagtac tgcgttttca tcgtcaagga
    31321 ttgctttagt gatacgagca agggctactg cgataccgta gtatgttgca ccttttttgt
    31381 tgatgattgt gtaggctgca tcacgaacac cttcgaacaa ttcaatcaat tcagcttctt
    31441 gaacattttg agtgtcttta aggaattctt caaggtttac accagcgatg ttagcgtgtg
    31501 accaaacagc gaactcagag tcaccgtgtt cacccatgat gtaggcgtgc actgaacgag
    31561 catccacatc caatttttca gcaagtgctt gacggaaacg agctgagtca agtgaagtac
    31621 ctgaaccgat aacgcgttct ttagggaaac cagagaattt ccaagttgag taagtcaaaa
    31681 cgtcaactgg gttagcagca acaaggaaga tacctttgaa accagattca acaacttgag
    31741 ttacgattga tttgttgata gcaaggtttt tacctacaag gtcaagacga gtttcacctg
    31801 gtttttgagg tgcacctgca gtaatcacaa caaggtcagc gtctgcacag tcagagtatt
    31861 gagctgcata gattttttta ggtgaagtga aggcaagggc gtgactaagg tcaagcgcat
    31921 caccaacagc tttttcatgc aattgtggaa tttcgataat tccaagctct tgtgcaattc
    31981 cttggttaac aagtgcaaaa gcgtaagatg aacctacagc accatcaccg acaaggataa
    32041 cttttttgtg ttgtttagtt gaagtcattg ttttaaacat ctccttaatt ttattagggg
    32101 attttcccta gacaacttca ttctatcact tttaaaaaac tttgtcacga atatgcctta
    32161 tagttctcga tgtaaacgtt ttagtggttt agaggctgaa atagatggga atttatggta
    32221 taatgttgtt acttactaat tgtgaaatga ggcatttatt aatgcaggat aaaaatttag
    32281 tgaatgtcaa tctgacaaag gagatgaagg caagttttat cgactacgcc atgagtgtta
    32341 tcgtagcgcg agctcttcct gatgttcgag atggcttaaa acctgttcac cgtcgcattc
    32401 tctacggaat gaatgaattg ggtgtgaccc cagacaaacc ccataaaaaa tctgctcgta
    32461 ttacagggga tgtcatgggt aaatatcacc cacacgggga ttcctctatt tatgaagcca
    32521 tggtccgtat ggctcaatgg tggagctacc gttacatgct tgtagatggt catgggaatt
    32581 ttggttccat ggatggagat agtgctgccg ctcaacgtta taccgaggca cgtatgagca
    32641 agattgctct ggaaatgctt cgtgatatca acaaaaatac agttgatttc gttgataact
    32701 atgatgccaa tgaacgggaa cccttggtct tgccagcgcg ttttccaaac cttttggtta
    32761 atggagcaac tggtatcgcg gttgggatgg caaccaatat tccacctcat aatctgggtg
    32821 aaaccattga tgcagtgaag ttggtcatgg ataatcctga agtgactacc aaggacttga
    32881 tggaagtctt gcctggacca gattttccaa ctggtgctct tgtcatgggg aaatcaggta
    32941 tccataaggc ttatgaaaca ggtaaaggtt cgattgccct acgttctcgt acagagattg
    33001 aaacgactaa gactggtcgt gagcgcatcg ttgtaacaga atttccttac atggtcaata
    33061 aaaccaaggt gcatgagcat attgttcgct tggttcagga aaaacgcatt gagggtatca
    33121 cagcagtacg tgatgagtca aaccgtgaag gtgttcgatt tgttattgaa gtcaagcgcg
    33181 acgcctcagc caatgttatt ctcaataacc tcttcaaaat gacccaaatg caaaccaatt
    33241 ttggtttcaa tatgctcgct atccaaaatg gtataccgaa aattttgtct cttcgtcaga
    33301 ttttggatgc ttatatcgag caccaaaaag aagtggttgt tcgtcgtaca cgttttgata
    33361 aggaaaaagc ggaagcgcgc gctcatatct tagaaggtct cttgattgcg ctagaccata
    33421 tcgacgaagt gattcgtatc atccgtgcta gtgaaacgga tgcggaagct caagctgagt
    33481 tgatgagcaa gtttaagctt tctgaacgtc aaagtcaagc tatccttgat atgcgtcttc
    33541 gtcgtttgac aggtttggaa cgcgataaga ttcaatctga gtatgatgac ctcttggctc
    33601 tgattgcgga tttagcagat attcttgcta agcctgaacg tgtttctcaa attatcaaag
    33661 acgaattgga tgaagttaaa cgtaaatttt ctgataagcg ccgtacagag ttgatgattg
    33721 gacaggtctt gagtctcgag gatgaggact tgattgaaga atcggatgtc ttgattaccc
    33781 tttctaacag aggctacatt aagcgtttgg atcaggacga gttcactgct caaaaacgtg
    33841 ggggtcgtgg tgtccaagga acgggagtga aagatgatga ctttgttcgt gagttagtgt
    33901 caactagcac ccatgatcat ctgctcttct tcacaaacaa gggacgtgtc tatcgtctta
    33961 aaggttatga aattcctgag tatggtcgga ctgccaaagg gctaccagta gtcaatctct
    34021 tgaaattgga tgaagacgaa agtattcaga cggttatcaa tgttgagtct gatcgcagtg
    34081 atgatgctta tctcttcttt acaacccgtc acggtattgt gaagagaacc agtgttaagg
    34141 agtttgccaa tattcgtcaa aatggtctca aagcgctgaa tttaaaggat gaagatgagt
    34201 taatcaatgt cttgttggca gaaggagata tggatattat cattggtacc aagtttggtt
    34261 atgcagttcg ctttaatcaa tcagccgttc gtggtatgag tcgtatcgcc actggtgtga
    34321 aaggtgttaa ccttcgtgaa ggagacacag ttgttggtgc cagcttgatt actgatcaag
    34381 atgaggttct tattatcaca gaaaaaggat atggtaagcg tacagtcgct actgaatacc
    34441 caacaaaagg tcgtggtggt aagggaatgc agacagctaa aattaccgaa aaaaatggct
    34501 tgctggccgg tcttatgact gttcaagggg atgaggattt gatgattatc actgatacag
    34561 gtgtcatgat tcgaaccaat cttgccaata tttcacaaac aggacgtgca actatgggag
    34621 ttaaagtaat gcgcctggat caagatgctc agatagtgac tttcacaacg gttgcggtgg
    34681 cagaaaaaga agaagttggg acagaaaacg aaacagaagg tgaagaataa tgtctcaaaa
    34741 aaataataaa aagaaaaaca agcgaaaaaa tctgctgaca aatatcctag caggatttct
    34801 gatattactg tcactggctt tgatttttaa tactcaaatt cgaaatattt tcatagtctg
    34861 gaataccaat aagtatcaag ttagccaggt atcaaaagaa aaattagaag aaaatcagga
    34921 tacagaaggc aattttgact ttgattctgt caaagctatc tcttcggaag ctgttctaac
    34981 ttctcaatgg gatgctcaaa aattaccagt tattggggga attgcaattc ctgaattgga
    35041 aatgaatttg ccgattttta aaggacttga taatgttaat ctcttctacg gagctggtac
    35101 aatgaaacgc gagcaagtaa tgggagaagg aaattatagt ctagctagtc accatatctt
    35161 tggtgttgat aatgctaata aaatgttatt ttctccttta gataatgcta aaaatggcat
    35221 gaagatttat ctaaccgata aaaataaagt ttatacttat gaaatacgtg aagtcaaacg
    35281 tgtgacaccg gatcgtgttg atgaagttga tgatagagat ggggtcaatg aaatcacatt
    35341 agtaacctgt gaagaccttg ctgctacaga acgtattatt gtcaaaggtg atttgaaaga
    35401 aacaaaagat tattcacaaa catctgatga aattctaaca gctttcaatc aaccatataa
    35461 acaattttat taatacaaat cagtgaaatc atggatttca ctgatttttt aagattttca
    35521 taaaaatata gtaaaatgaa ataagaatag gacgaatcgt tcaggacagt caaatcgatt
    35581 tctaacaatg ttttagaagt agaggtgtac tattctagtt tcaatctact ataaactttt
    35641 atgaaataca gaaaacgctt cctaaaacct aaagtttgtg atataattat caagaaaaaa
    35701 gatttaggag tttattatgg tttcttcaga atttatctca aagattgaat ttgcttgcaa
    35761 taagaaagaa agtctttata gtcaaagcaa atttaagtat gcgattcgtt cgatgttcgc
    35821 aggtgcattt ttaaccttca gtactgctgc aggtgcagtt ggggctgact tgattaataa
    35881 aattgcacca ggtagtggac gcttcctctt tccattcgtt tttgcttggg gcttggccta
    35941 cattgttttt ttgaatgccg agttggtcac ttcaaacatg atgttcttga ctgctggtag
    36001 tttcttaaaa aaaatctctt ggagaaaaac agctgagatt ttactatact gtaccttgtt
    36061 caaccttatc ggagccttga tagcagggtg gggctttgct cattcggcag cctatgcgaa
    36121 tctgacacac gatagtttca tctcaggtgt tgttgagatg aagttaggcc gctcaaatga
    36181 attggtcttg cttgaggcga ttttggcaaa tattttcgta aatattgcga ttctgtcatt
    36241 tattttggtc aaagatggtg gtgccaaact ttggcttgtg ttgtcagcta tttacatgtt
    36301 tgtattctta acaaacgagc acattgcggc gaactttgct tctttcgcga ttgtgaaatt
    36361 cagtgttgct gcggattcaa ttgccaactt cggtgttgga aatatgcttc gccactgggg
    36421 tgtgactttc atcggaaact ttatcggagg aggcctcttg atgggtcttc catatgcctt
    36481 cctcaataaa aacgaagata cttatgtaga ttaagaaaat gagcacgatt gagtcgtgct
    36541 tttttcattt tcaaaataag gtaatagcta tttcttatat caaaatatag aaaactgata
    36601 tttgtaaact ataactcaag gtgctacaat atccttaata aaatgatatg gaggtcacct
    36661 tatgacttgt gattttaaat ttgaaactct acaactacat gctggtcaag ttgtggctcc
    36721 agctactaag tctcgtgcag tgccgattta tcaaacaaca tcttttattt ttgatgacac
    36781 gtaggaaggt gctgatctgt ttgccttgag gaaaccaggg aacatttata ctcgtatcac
    36841 caatcctaca acagctgccc ttgaaggtgg tgttgaagcg ctagcaacag catcaggtat
    36901 gactgcagtg acttatacga ttttggcgct tgcccatgct ggtgaccatg tagtggctgc
    36961 ttcgactatt tacggtggaa ccttcaatct tttgaaagaa ccccttcctc gttatggtat
    37021 cacaacaacc tttgtcgatg ttgataattt ggaggaagta gaagcagcta tcaaagacaa
    37081 taccaagctt gtcttgattg aaaccttggg taactccttg attaatattc cagacctgga
    37141 aaaactggca gagattgctc ataaacatca aatcccactt gtgtcagaca atacttttgc
    37201 aataccttat ttgattaacg tcttctctca tggcgttgac attgccattc actctgcgac
    37261 taagtttatc ggtgggcatg gtacaactat tggaggaata attgtcgata gtggtcgttt
    37321 tgactggacg gcttcaggga aattccctca atttgttgac gagggtccaa gctgccacaa
    37381 tttgagttat acttgtgatg tgggtgcagc agcctttatt atagctgttc gagttcaatt
    37441 gcttcgtgat acaggtgcag ccttgtcacc attcaatgct ttcctcttgc tacaaagact
    37501 tgaaacctct tcacttcgtg tggaacgcca tgtacaaaat gctgagacaa ttgttgattt
    37561 tcttgtcaac catcctaagg tagaaaaggt aaattatcca aaacttgcag atagtcctta
    37621 tcatgccttg gctgagaaat acttgccaaa agatgtcggt tcaatcttta ccttccatgt
    37681 caaaggtggc gaggaagaag cacgcaaggt cattgataat ttagaaatct tttctgacct
    37741 tgcaaacgcg gcagatgcta aatcgcttgt tgtccatcca gcaacaacca ctcacggtca
    37801 attgtcagaa aaagacctag aagcagcagg tgtcacacca aactaaattc gtttgtcaat
    37861 cggtcttgaa aatgtagaag atttgattga agacttgcgc ttggccttgg aaaaaattta
    37921 aagtaaaaga agataaacag tgggcttcga ctcactgttt ttgattttcc ctcaggcatg
    37981 atataatggt taaagaagtc tagaaagagg aacgatatga acgaaatcaa atgtcccaac
    38041 tgtggggaag tctttacagt aaatgagagt cagtatgccg aactcttgtc ccaagtgaga
    38101 acggcagagt ttgataagga actacacgat aggatgaagc aggaactggc cttggctgag
    38161 caaaaggcca tgaatgagca acagactaaa ctggctcaga aggatcaaga aattgcgcaa
    38221 ttacagagtc agatccaaaa ctttgataca gaaaaagaat tggccaagaa agaggttgaa
    38281 cagacaagcc atgaggctct cttggctaag gacaaggaag tacagctctt agaaaatcag
    38341 ttggctacct tgcgtttgga gcatgaaaat caactgcaaa agaccctttc tgacctagaa
    38401 aaagaacggg atcaggttaa aaaccaacta cttttgcagg aaaaggaaaa tgaattatct
    38461 ttggcttctg ttaagcaaaa ctacgaagcc cagctcaagg cagctagtga acaagtcgag
    38521 ttttataagg attttaaggc tcaacaatct acaaaagcga ttggggaaag cctagaacag
    38581 tatgcagaga gtgagtttaa caaggttcgt agtttcgcct ttccaaatgc ttactttgag
    38641 aaggataaca aggtctcttc gcgtgggtct aaaggggact ttatcttccg tgagtgtgat
    38701 gaaaatggag ttgaaatcat ttctatcatg tttgagatga aaaacgaagc agacggaaca
    38761 gagaagaagc acaagaatgc agatttttac aaggaattgg acaaggaccg tcgggagaag
    38821 aactgtgagt atgccgtttt ggtgaccatg cttgaggccg ataatgacta ctttaacaca
    38881 gggattgttg acgtcagcca cgagtatgaa aaaatgtatg ttgttcgtcc tcaattcttt
    38941 atccagttga ttggtctctt acgtaatgcg gcgctaaatt ccctaaaata caagcaggag
    39001 ttggccttgg ttcgcgagca aaatattgac attacgcatt ttgaggaaga cttggatgcc
    39061 tttaagctag cttttgctaa gaactataat tcagcttcga ctaactttgg aaaagctatt
    39121 gatgaaatcg acaaggccat caaacgcatg gaagaggtta agaaattcct gactacatct
    39181 gaaaaccaac tccgtctagc taacaacaaa ttggaagatg tctctgttaa aaaattgacc
    39241 cggaaaaatc caacaatgaa agcgaagttc gaagcactga agggggagta gaaagcaaaa
    39301 atgaacggta ttatcaactt aaaaaaagaa gcaggaatga cctcgcatga tgcggttttt
    39361 aaactgcgta agattttggg aaccaagaaa attggtcatg gtggaacctt ggatccggat
    39421 gtggtgggtg ttttgccgat tgcggttggc aaggcgacac gcatggtcga gtttatgcag
    39481 gacgagggta agatctatga gggggaaatc attctgggct attccacgac gactgaggat
    39541 gctagtgggg aagtggtcgc agaaacccct gttttgtctc ccttggatga aaagcttgtt
    39601 gatgaagcga ttgctagctt gactgggcct attactcaga ttccccctat gtattcggca
    39661 gttaaggtta atggtcgcaa gctctatgag tatgcgcgtg ctggtcagga agtggagcgt
    39721 ccagaacgtc aggtgaccat ttatcaattt gagcgaacaa gtccgatttc ttatgatggc
    39781 caacttgccc gattcacttt tcgtgtaaaa tgcagtaaag ggacttacat ccgtactttg
    39841 tcagttgatt tgggtgaaaa gcttggttat gcggctcata tgtcccattt gactcgtact
    39901 agtgctgctg gcttacaatt agaagacgct cttaccttgg aggaaattgc tgaaaaagta
    39961 gaggctgggc aattagattt tctccatcct ttagagattg ggacaggtga ccttgtcaaa
    40021 gttttcctaa ctccagaaga ggctacagaa gttcgctttg gtcgttttat tgagctagac
    40081 caaacggaca aagaactggc tgcctttgaa gatgataaat tgttagccat tctagaaaaa
    40141 cggggcaatc tctataagcc aaggaaggtt tttagctaga tcgtttagga ataaaaatcg
    40201 ggtgatagat aacaattgct tgataaaccc ccatactaat agtagaatgg ttttgggaat
    40261 tataatattc caattgttgc gagttgtaga tactcaaata atctatatag aaatttagag
    40321 gtgtgaaatg aagcaactta aaattctttc agataaatat ttagagtcca tgacaggttc
    40381 tggtgggaac ttaggtctag gatttggtgt gataattcca tgatgtgaaa tgagtttcga
    40441 gaaagggtgg agcaacttct tcaacaaaaa gaaataaatg aaaatagtga gttgagtcac
    40501 ctgtttcgtc ttgctataca aaatttagac agaaatgaaa aataccaatc ggtcatggcc
    40561 aatttgagtc aagggttgtc actttacctc atgacgcatc attaccaggc acctaagtct
    40621 gtcattgatt ttggtttatg gattgccaaa gctcctagcc aggaaagagg gagactggct
    40681 ttcttgcaga tgcttgctca aaccctacag ggctttcgtt aaaactgtcg aacatcagag
    40741 ggaagactct ggtgtttttt gctgatgaga ctataaattt tgtaaaaaat gtgatagaat
    40801 agacgacgga taaaataacg gaggatagca tgcaaaatag accaatcatt attggagtga
    40861 caggtggttc tggtggtggt aaaaccagtg tttcaagagc cattttatcg cattttcctg
    40921 atgaaaagat ttccatgatt gagcatgatt catactacaa ggatcagtct catttgacct
    40981 ttgaagagcg tgtcaaaacc aactatgacc atccttttgc ctttgataca gacttgatga
    41041 tcgagcagat taaggaattg ttggcagggc gtccggtgga catcccgacc tacgactata
    41101 cagagcatac acggagtagc aagacctatc gtcaggagcc tcaagatgtc tttatcgttg
    41161 agggcatttt ggtcttggag gacaagcgtc tgcgcgattt gatggatatc aagatttttg
    41221 tggatacgga tgacgatgtg cgtattattc gtcgtatcaa gcgtgatatg gaggaacgtg
    41281 gccgtagcct tgatagcgtt attaaccagt acttaggtgt ggtcaaacca atgtaccacc
    41341 agtttatcga gtcaactaag cgttatgctg atatcgtcat tcctgaaggg gttagcaata
    41401 ccgtggctat cgacctgttg acgaccaaga ttgcaaagat tttggaagaa gctcgaaaca
    41461 gcaaataatc acatgtggag gccttgcctc ctttttctat ttttccctca taatggtaca
    41521 taaatggaga tttttaggca tatttttggt ataataatac ccataaaaga gcaagtaaat
    41581 gaatagtagg tggagatgga aaagtattta tcggtaacaa ctttgaccaa atatctgaaa
    41641 atgaaattcg ataaagaccc atacttggaa cgggtctatt taactggtca agtttccaac
    41701 tttcgtaaac gacctactca ccaatatttc tccctaaagg atgaccatgc agttattcaa
    41761 gcgaccatct ggtctgggat ttatcagaaa ttagggtttg acctggaaga aggaatgaag
    41821 atcaatgtga ttgggcgtgt acaggtctat gaaccaagtg gtagctactc catcatcatt
    41881 gaaaaagctg agcctgatgg ggttggggcg cttgcgattc agtttgaaca acttaagaaa
    41941 aaattgacag aagaaggcct gtttcaagaa cgcttcaagc aagctctacc ccaattttct
    42001 aagagaattg gggtagtaac cagccgtagt ggagccgtta ttcgagatat tatcacgacc
    42061 gtcagcaggc gattcccagg tgttgacatc cttctttatc ctaccaaggt tcaaggtgaa
    42121 ggggctgcgg aggaaattgc tagaaatatt gcgcgtgcta atcaacggga cgatttggat
    42181 ttgctcatta ttggtcgtgg aggtggttct attgaggatc tctgggcctt taacgaagaa
    42241 attgtggtac gagctatttt tgaatctcgt ttgccagtta tctctagtgt ggggcatgag
    42301 acggatgtga ccttggcaga ttttgtggca gatcgacgcg ctgcaacgcc aacagcggcg
    42361 gctgaactgg caacacctgt gaccaagttg gatgtattag ctcatttgca aaatcaggaa
    42421 aaacggatgg caacggcagt ccgaaatgtt ctatctaaga aacaagaggc tttgaaaaaa
    42481 tgcagtcagt ctgttatctt tagacaacct gagcgcttgt atgacggtta tttgcaacgc
    42541 ttggaccaac tgcaactgcg tttgaaacaa agtttgcgaa ctcggatttc tgataacaaa
    42601 caattagttc aagcaagaac tcatcaatta gtacaattat cacctgttac caaaatccaa
    42661 cgctatcaag accgtttagg acagttggac aagctcttag gtagccaaat ggcgttagtt
    42721 tatgacgcca aggttgctga ggccaagcga ctttcggaag ctttgctcat gttggatact
    42781 agccgaatcg tggcgcgtgg ttatgctatt gtcaaaaaag aagagtccgt tgtagattcg
    42841 gttgagagtt tgaagaaaaa agaccaagta acgcttttga tgcgagatgg tcaagtagaa
    42901 ttagaggtta aagatgtcaa aacaaaagaa atttgaggaa aatctagcag aactggaaac
    42961 cattgtccaa agtttggaaa atggtgaaat tgctctggaa gatgcgatta ctgcctttca
    43021 aaagggcatg gtcttgtcaa aagagctcca agctacgctg gacaaggctg aaaagacctt
    43081 ggtcaaggtc atgcaagaag acggaacaga aagtgatttt gaatgaaaaa gcaagaaaaa
    43141 ttagctcttg tcgagtcggc tttggaagat ttttatggag accagcagtt tgcctctagt
    43201 ttacgggagt ctgttctcta ttctattcat gctggtggca agcgtattcg gccttttctc
    43261 ttgttagaag ttctggaatc cttgcaggtt accatcaaac ctgctcacgc gcaggtagct
    43321 actgccttgg agatgattca tacagggagc ttgattcacg atgaccttcc tgctatggat
    43381 gatgacgatt atcgaagagg gcggttaacc aatcacaaga aattcggtga agctatggcc
    43441 attttggctg gagatgcctt attcttagac ccatatgcct tgattgcgca ggcagatttg
    43501 ccaagtcaga tcaaggtgga cttgattgcc aacttatccc ttgcttcagg tagtctgggt
    43561 atggtggcag ggcaagtttt ggatatggag ggcgaacacc agcacttgtc tctggaagaa
    43621 cttcagacta ttcatgccaa taagactggg aagttactag cctatccctt ccaagcggca
    43681 gctattatag ctgaattgtc acctgaaatg caggtgaagc tgaaaactgt gggtgaattg
    43741 attggacttg cttttcaagt cagagatgat gtactggatg tgacagctag ttttgaggaa
    43801 atcggcaaga cacctcaaaa ggatctgcag gcagaaaaat caacctatcc tgccttgttg
    43861 ggcttggaag agtccattgc cttttgtaac caaaccctgg atcaagctaa tgaaaaatta
    43921 gaagaaattg cccagcagct tccctttgaa acagaatcga ttgtaagtgt agtagaaagt
    43981 ttgagaatca atggctaagg aaagagtgga tgtactagct tataaacagg ggttgtttga
    44041 aacgagagag caggccaagc gaggtgtgat ggctggtcta gtcgtagcag tccttaatgg
    44101 agaacggttt gacaagccag gagagaaaat tccagatgac accgaattaa aactcaaggg
    44161 ggagaaactc aagtatgtca gccgtggtgg tttgaaactg gaaaaggcct tgcaggtctt
    44221 tgatttgtcg gtggatggcg cgactacgat tgatatcggg gcctctactg gaggttttac
    44281 cgatgtcatg ctacagaata gtgccaagtt ggtctttgca gtcgatgttg gtaccaatca
    44341 gttggcttgg aaattacgcc aagacccacg agttgtcagc atggagcagt tcaattttcg
    44401 ctatgctgaa aagactgatt tcgagcagga gccgagcttt gccagtattg atgtgagttt
    44461 catttccctt agtctgattt tgccagcctt gcacagtgtc ttggctgatc aaggtcaggt
    44521 ggtagcactt gtcaaacctc agtttgaggc aggacgtgag cagattggga aaaatggaat
    44581 tattcgagat gctaagattc atcagaatgt ccttgaatct gtaacagcta tggcagtaga
    44641 ggcaggtttt tcagtccttg gcttggactt ttctcccatc caaggtggac atggaaatat
    44701 tgaattttta gcgtatttga aaaaagaaaa gtcagcaagc aatcagattc ttgctgagat
    44761 taaagaagca gtagagaggg cgcatagtca atttaaaaat gaataaaaaa gaaagacttg
    44821 aaaaaattag aagattggtg acagattatc aaatcggcac gcaagaagaa attgtagaac
    44881 atttgaaaga agcaggtatc actgccactc aggcgacggt atcccgagat atcaaagagt
    44941 taggtattgt caaaattcct ttgagagaca acacctatgt ctacgaattg ccaaaatcaa
    45001 tcgtaaaaag tctgcaactg gctgaagaca atatcgaatc ggctgaattg atggataaga
    45061 tgatcaatct ccaagttatt ccaggaaata cggcttttgt aaaagctcag ttaatcgaga
    45121 cttttgcaga caagattttt agctgtttga ctgatgatag ctcgatttta gtcattgcca
    45181 gaagtggaag tctagcagag gaaatctttg aacaagtaaa aaattggtag gtctatatgt
    45241 tacttgaaat ttcgataaaa aactttgcca ttattgaggc tatttccctc aattttgaaa
    45301 aggggatgac tgtcctgact ggtgaaacgg gtgcagggaa gtcgattatc attgatgcca
    45361 tgaatatgat gttgggagct cgtgcgacga cagatgttat tcgtcatggt gcaccaaagg
    45421 cagagattga ggggcttttc tcagttgaga atagtcgtct tttacaggaa atttttgatg
    45481 agcaaggttt agaattaggt gatgaaatta tcatccgtcg ggaaatcttg caaaatggtc
    45541 gtagtatcag ccgtgtaaat ggtcagatgg ttaatctgtc tgttttgcga actattgggc
    45601 aacatcttgt agatattcat ggtcagcatg accatgagga gttaatgcgt ccccaactgc
    45661 atatccagat gttggatgaa tttggtgatg ccgctttttg ggacttgaaa gaaacctatc
    45721 aaacgagttt tgatgcctat cggaaaatgc gcaagcaggt tctggaagtc aagaaaaacc
    45781 aacaggaaca caaggcacgt atcgaaatgt tggaatttca aatggcagag attgaggcag
    45841 caaacttgca ggctggagaa gacttggatc tcaatcaaga gcgagataaa ctcctcaacc
    45901 acaaaaatat tgcggataca ctgaccaatg cctacagtat gttggacaat gaagattttt
    45961 caagtctggc caatgttcgt tcagccatga atgacatgga aagtgtcgaa gagtatgacc
    46021 ctgaataccg tgaaatttca agctctctgt ctgagaccta ctatgtttta gaagacatta
    46081 gcaaacgttt ggaagctatc attgaggacc ttgattttga tggcaatcgc ctcatgcagg
    46141 ttgagaatcg tttggacctc cttcatacta ttactcgtaa gtatggtggg actgttgatg
    46201 atgttttgct ttattttgcc aagattacgg aagaatacaa tctcttgaca ggcaataatc
    46261 tttcgtctga ggacatggaa gcagagctta agaagttgga agtcaatctt gtcaatttgg
    46321 caggtcaact tgcttctgct cgtcataatt tggctcagca actcgaagct gagattaaac
    46381 aagaactgca agatctttat atggaaaaag cccagtttca ggttcgtttt agtaagggaa
    46441 aattcagtcg tgagggaaat aaaatggttg agttttatat ttcaaccaac cctggagaag
    46501 actttaaacc cttggttaag gttgcttctg gaggggaatt atctcgtctc atgttagcca
    46561 ttaagtctgc cttttcacgt aaagaaggca agactagcat tgtctttgat gaggtggata
    46621 cgggagtttc aggtcgtgtt gctcaagcta ttgctcagaa aattcataaa attggtcagc
    46681 atggtcaggt tttggctatc tcccatttgc cacaagtaat tgcgattgca gattatcaat
    46741 tctttattga gaagattagt aatgaccatt caacggtttc gactgttcgt ctcttgacgg
    46801 tcgaagagcg agtggaggaa gttgccaaga tgttggcagg tgatgatgtg acagaagcag
    46861 ccctgacgca agcaagagaa ttgttgagaa acagggagaa ataagatgac agattattat
    46921 gtaattggag atgttcacgg aaaagctggg atgctggaag accttctcaa aacctgggat
    46981 ggtcagcccc agttgctctt tctaggtgat ttgattgaca gaggtgagga tagtcaccgt
    47041 gttcttgaaa tggtcaagga cttggtggac aatcaagggg ctatctgttt gtccggaaac
    47101 cacgagtata tgtttttgac ttggctagat gacccagaag aaagttatga ccattatagt
    47161 cgcaatggtg gagatacaac cattaactct atcctaggtc gtcccttgga tgcaccagtt
    47221 gatggagtag aagatgccaa gcgggttgcc gctgaagcgg cagacttggt cgaattcatt
    47281 cgtcaaatgc catttgtagt agagacagac aagtatatct ttgttcacgc aggtattgat
    47341 ttgaccttgg acgactggca tgaaacaaca gattataaaa aagtatggct tagaaaacca
    47401 ttccacggag ctgaaaatca tactggaaaa accattgtct tcggtcatac accggtctat
    47461 ggtttattac agcaagaacg cggtacatct gagctttgga ctacagaaga tggcaagatt
    47521 ggaatggatg gaggagctgt ttatggtggt gtccttcacg ggattgtctt tacagaccaa
    47581 ggaatgacag aacaccactt tatcgaaaat gacggctttg tcgctgaaga ttagtactcc
    47641 tagcagggta tggtcttgtc aaaatatcaa aaacaattta taataaatag ataccctgaa
    47701 aggaagagaa tcatgaactt agaagaattg aaaaaacgac aggagaagat ccgtaacttc
    47761 tctattatcg cccatattga ccacggaaaa tcaactctag cagaccgcat tttggaaaaa
    47821 acagagacgg tttcaagtcg tgaaatgcag gcccagcttt tggatagcat ggagctagag
    47881 cgggaacgtg gaattactat taagttgaat gccatcgagt tgaattacac tgcaaaagat
    47941 ggggaaactt atattttcca cttgattgac acaccagggc acgttgactt tacctatgaa
    48001 gtttcacgtt cgctagctgc ctgtgagggt gctattttgg tggtcgatgc ggctcaagga
    48061 attgaggctc aaactcttgc caacgtttat ctggctttgg ataatgattt ggaaatcatg
    48121 cctatcatta ataaaattga cctgccggct gcagatccgg agcgcgtgcg tacagagatt
    48181 gaagatgtga ttggtttgga tgccagtgaa gcagttttgg cttctgccaa ggctggtatt
    48241 gggattgaag aaatcctcga gcaaattgta gaaaaagtac cagcaccaac gggtgatgtg
    48301 acggcgccac ttaaggcctt gattttcgac tctgtttacg atgcttaccg tggggttatc
    48361 ctccaagtgc gtgtcatgga cggagtggtc aaacctggtg ataagattca gctcatgagc
    48421 aatagtaaga cctttgatgt ggccgaagtc ggtattttta caccaaaagc ggttggtcgt
    48481 gatttccttg cgactggtga tgttggttac attgcggcgt ctatcaagac ggttcaggat
    48541 actcgtgtgg gtgataccgt taccttggca accaatcctg cggcagaacc attacatggt
    48601 tataagcaga tgaatcctat ggtctttgcg ggtctctacc caatcgaatc aaacaagtac
    48661 aatgacctgc gtgaagcgct tgaaaaattg caactgaatg atgctagtct tcagtttgaa
    48721 ccagaaacat ctcaggcact tggatttggt ttccgttgtg gatttcttgg acttctccat
    48781 atggatgtta tccaggaacg tttagagcgt gagttcaata ttgacctcat catgacagct
    48841 ccgtctgtta tttacaaagt taatttgacc gacggtgagt ctatggatgt gtctaaccca
    48901 tctgagtttc cagacccaac taagattgcg accattgaag agccttatgt caaggcgcaa
    48961 atcatggtac cacaggagtt cgtcggagca gtaatggagc tagctcagcg taagcgtggg
    49021 gactttgtga ctatggacta tattgatgat aaccgtgtca atgttatcta tcaaattcct
    49081 cttgctgaaa ttgtctttga cttctttgat aaacttaagt cttcgacacg tggttatgca
    49141 agctttgact acgaattgtc agaatatcgc ccatctaagc tggtgaaaat ggatattctt
    49201 ctcaatggag ataaggtgga tgccctcagc tttatcgttc acaaggactt tgcctacgaa
    49261 cgtgggaaac tcatcgttga taaactcaag aaaatcatcc ctcgccaaca atttgaagtt
    49321 ccaatccaag cggctattgg acacaagatt gtcgctcgta ctgatatcaa ggcccttcgt
    49381 aagaacgtac ttgctaaatg ttatggtggt gacgtttctc gtaagcgtaa actccttgaa
    49441 aaacaaaaag ctggtaagaa acgcatgaaa tccatcggat cagttgaagt tccgcaagaa
    49501 gccttcctca gcgtcttgag tatggatgaa gaataagtta tcagaaatgc ctttccttgt
    49561 tcacaggaaa tttataagaa tcaatagtaa agcaggctta gatggtctgc ttttttagtt
    49621 tttatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt atgtatggtt
    49681 actgacttcg tcagtttcat ctacaacctc aaaaccatgt tttgagctga cttcgtcagt
    49741 ttcatctaca acctcaaaac tgtgttttga acaacctgcg gctagcttcc tagtttgctc
    49801 tttgattttc attgagtatt agaacagaaa aaatgcttgg agtatttgtt tgtgtgttta
    49861 cttttatata acaaactata aacacaacaa aaatataaaa aaagagacaa aaaagaacag
    49921 aaagtaatta acaacgattt catatagtgt tatacttata gcataaagtt aatggaaaga
    49981 agggaaaacc ttatggtatt agattatttc tttgacaaaa accttgtgtt ttgcttagaa
    50041 gcggataatc aagaataact ctttgatcag gtagcaagct tgttggagga acgagaaatt
    50101 gt
//
LOCUS       DAVAZV010000008        48474 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVAZV010000008 DAVAZV010000000
VERSION     DAVAZV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.008"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQT46_000444"
     CDS             complement(308..1474)
                     /gene="recA"
                     /locus_tag="VQT46_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET2370533.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            complement(1529..2785)
                     /locus_tag="VQT46_000445"
     CDS             complement(1529..2785)
                     /locus_tag="VQT46_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET2370534.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            complement(2869..3885)
                     /locus_tag="VQT46_000446"
     CDS             complement(2869..3885)
                     /locus_tag="VQT46_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2370535.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEKALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            complement(3893..4411)
                     /locus_tag="VQT46_000447"
     CDS             complement(3893..4411)
                     /locus_tag="VQT46_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370536.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQT46_000448"
     CDS             complement(4401..4844)
                     /gene="tsaE"
                     /locus_tag="VQT46_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET2370537.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILTGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            complement(4930..5550)
                     /locus_tag="VQT46_000449"
     CDS             complement(4930..5550)
                     /locus_tag="VQT46_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370538.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            complement(5933..6796)
                     /locus_tag="VQT46_000450"
                     /pseudo
     CDS             complement(5933..6796)
                     /locus_tag="VQT46_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            6961..7155
                     /locus_tag="VQT46_000451"
     CDS             6961..7155
                     /locus_tag="VQT46_000451"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370539.1"
                     /translation="MKKKRVSRMKKNRGIQKLAILVLLGVFMFSNTIPYQQFIQKNRQ
                     LEIRVQSQKKSNGLDVGKAD"
     gene            7470..7766
                     /locus_tag="VQT46_000452"
     CDS             7470..7766
                     /locus_tag="VQT46_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET2370540.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPNNW
                     GAFSNYYHGSQYHWAYVGSNGRNNQKTVYAGARSAAYAFVNTNFGEQVTFDAGW"
     gene            7869..9884
                     /locus_tag="VQT46_000453"
     CDS             7869..9884
                     /locus_tag="VQT46_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2370541.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFIALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            9886..10518
                     /locus_tag="VQT46_000454"
     CDS             9886..10518
                     /locus_tag="VQT46_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370542.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            10659..10937
                     /locus_tag="VQT46_000455"
     CDS             10659..10937
                     /locus_tag="VQT46_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET2370543.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQT46_000456"
     CDS             complement(11446..11859)
                     /gene="ndk"
                     /locus_tag="VQT46_000456"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET2370544.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQT46_000457"
     CDS             complement(11970..15647)
                     /gene="rpoC"
                     /locus_tag="VQT46_000457"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET2370545.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKAEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGEVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQT46_000458"
     CDS             complement(15680..19291)
                     /gene="rpoB"
                     /locus_tag="VQT46_000458"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2370546.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSSLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            19707..19777
                     /locus_tag="VQT46_000459"
     tRNA            19707..19777
                     /locus_tag="VQT46_000459"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19739..19741,aa:Cys,seq:gca)
     gene            complement(19975..21306)
                     /locus_tag="VQT46_000460"
     CDS             complement(19975..21306)
                     /locus_tag="VQT46_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET2370547.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQT46_000461"
     CDS             complement(21597..22421)
                     /gene="endA"
                     /locus_tag="VQT46_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET2370548.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSTANSPKTKLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(22460..22648)
                     /locus_tag="VQT46_000462"
     CDS             complement(22460..22648)
                     /locus_tag="VQT46_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET2370549.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDSW
                     AILSPAKWQELIHKFTGN"
     gene            complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQT46_000463"
     CDS             complement(22641..23924)
                     /gene="murA"
                     /locus_tag="VQT46_000463"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2370550.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(23948..24178)
                     /locus_tag="VQT46_000464"
     CDS             complement(23948..24178)
                     /locus_tag="VQT46_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET2370551.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(24236..25273)
                     /locus_tag="VQT46_000465"
     CDS             complement(24236..25273)
                     /locus_tag="VQT46_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET2370552.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQT46_000466"
     CDS             complement(25257..25745)
                     /gene="coaD"
                     /locus_tag="VQT46_000466"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET2370553.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLCVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATCLVRGLRNASDLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACYVPESILEEIRNEK
                     KD"
     gene            complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQT46_000467"
     CDS             complement(25735..26274)
                     /gene="rsmD"
                     /locus_tag="VQT46_000467"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET2370554.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEVGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKTVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(26339..27331)
                     /locus_tag="VQT46_000468"
     CDS             complement(26339..27331)
                     /locus_tag="VQT46_000468"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET2370555.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(27443..28126)
                     /locus_tag="VQT46_000469"
     CDS             complement(27443..28126)
                     /locus_tag="VQT46_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET2370556.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(28182..28922)
                     /locus_tag="VQT46_000470"
     CDS             complement(28182..28922)
                     /locus_tag="VQT46_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET2370557.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRNQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            28956..29234
                     /locus_tag="VQT46_000471"
     CDS             28956..29234
                     /locus_tag="VQT46_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET2370558.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            29312..30238
                     /gene="yidC"
                     /locus_tag="VQT46_000472"
     CDS             29312..30238
                     /gene="yidC"
                     /locus_tag="VQT46_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2370559.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQT46_000473"
     CDS             complement(30313..31107)
                     /gene="pflA"
                     /locus_tag="VQT46_000473"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET2370560.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(31233..32483)
                     /locus_tag="VQT46_000474"
     CDS             complement(31233..32483)
                     /locus_tag="VQT46_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET2370561.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQT46_000475"
     CDS             complement(32550..33377)
                     /gene="purR"
                     /locus_tag="VQT46_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET2370562.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLHEFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(33644..34585)
                     /locus_tag="VQT46_000476"
     CDS             complement(33644..34585)
                     /locus_tag="VQT46_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET2370563.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            complement(34575..35831)
                     /locus_tag="VQT46_000477"
     CDS             complement(34575..35831)
                     /locus_tag="VQT46_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET2370564.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(35833..36495)
                     /locus_tag="VQT46_000478"
     CDS             complement(35833..36495)
                     /locus_tag="VQT46_000478"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET2370565.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLASYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(36458..37114)
                     /locus_tag="VQT46_000479"
     CDS             complement(36458..37114)
                     /locus_tag="VQT46_000479"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET2370566.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQT46_000480"
     CDS             complement(37125..38003)
                     /gene="rsgA"
                     /locus_tag="VQT46_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET2370567.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(38596..39369)
                     /locus_tag="VQT46_000481"
     CDS             complement(38596..39369)
                     /locus_tag="VQT46_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET2370568.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQT46_000482"
     CDS             complement(40059..40931)
                     /gene="rsmA"
                     /locus_tag="VQT46_000482"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET2370569.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            complement(41182..41400)
                     /locus_tag="VQT46_000483"
     CDS             complement(41182..41400)
                     /locus_tag="VQT46_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370570.1"
                     /translation="MENMTNPLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFFDTQ"
     gene            complement(41468..42109)
                     /locus_tag="VQT46_000484"
     CDS             complement(41468..42109)
                     /locus_tag="VQT46_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370571.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(42111..44141)
                     /locus_tag="VQT46_000485"
     CDS             complement(42111..44141)
                     /locus_tag="VQT46_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET2370572.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMIN
                     QPVASREEVTEVLSHLAVEHNSLIARRIVEPNEAGETLFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLAATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQFICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVYLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSTYYQRLFTDYL
                     QNFSSESVEVMSQKYYLPQVSLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(44410..45309)
                     /locus_tag="VQT46_000486"
     CDS             complement(44410..45309)
                     /locus_tag="VQT46_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2370573.1"
                     /translation="MLIGQKIKEIRIEKGVSRPYFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAK
                     LIGDGFLVKKLTEEWQEDVKKYL"
     gene            complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQT46_000487"
     CDS             complement(45381..45941)
                     /gene="rnmV"
                     /locus_tag="VQT46_000487"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET2370574.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINAQDIERI
                     QRLHQRQGVIVFTDPDFNGERIRRMIMTAIPTVRHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(45941..46714)
                     /locus_tag="VQT46_000488"
     CDS             complement(45941..46714)
                     /locus_tag="VQT46_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET2370575.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYDQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKVTDLQEAAKELPLDKILVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(47019..47912)
                     /locus_tag="VQT46_000489"
     CDS             complement(47019..47912)
                     /locus_tag="VQT46_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET2370576.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLENTPGGDKGGNTGSSDANANAGGGSQAGGSAHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKDKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIVMVTVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQT46_000490"
     CDS             complement(48196..48330)
                     /gene="rpmH"
                     /locus_tag="VQT46_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET2370577.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
BASE COUNT        13991 a        10915 c         9041 g        14527 t
ORIGIN      
        1 taaagctatt atatcagctt tccagaggag cgacaagaaa cagcaaactt atatatagcg
       61 gaatgaaata aggaaagtca aatcgatttt taacaatgtt ttagaagtag atatgtacta
      121 ttctagtttc gatctattat agttggttga gtttggaata gtacgctgta gctgctaaaa
      181 catttctaga aattaatttg actttcctaa tagagttgtt catatcttat ttcaagctac
      241 tatatataat ctaaaaactt gaatcaaaaa tcgaaaaagt agcggatttc tccactgctt
      301 taacagctta ttcttcaatt tcgatttcaa gttcatcgcc taagtcaagc ggaacttctt
      361 cattcactgc ttcttctttc tttggctcat cttttttgtt ttcagtatct tgttctgaaa
      421 cttcttctcc atcaatcaag ccaaatttag aacggacttg cttatcaatt tcatcaaaga
      481 tttctgggtg ctctgccaag tatttcttag cattctcaga accttgccca attttttcat
      541 ctttgtaaga ataccaagcc cctgcttttt tgataatatc caaatcgctt gcaatcttca
      601 aaagctcacc agtcttagaa attccttctc cgtacataat ttcaactacg gcttccttaa
      661 acggtggagc taccttattt tttacaacct taatcttagt ttctttaccg acattggttt
      721 ctttttggtc accagttccc ttaatttgtg tattaccacg aacatccaag cggactgaag
      781 catagaattt caaagcacgt ccgcccggtg ttgtttctgg atttccaaac atcactccaa
      841 ctttttcacg caattggttg ataaaaatgg caattgtttt ggttttattg atagaggcgc
      901 caagtttacg catggcctgg ctcatcatac gagcctgcaa accaacatgg ctatctccga
      961 tatctccatc aatttccgca cgaggaacaa gggcagcaac tgagtcgact acgacaagat
     1021 caactgcacc tgagtcaatc aattttcccg caatctcaag accttgctct cctgagtctg
     1081 gttgagacaa gagcaattcg tcaatattga caccaagggc cgcagcataa gctggatcaa
     1141 gggcatgttc cgcatcgata aaagcagcaa tcccaccttc tttttgcgct tgtgcaactg
     1201 catgaagggc aaccgttgtc ttaccagatg actctgggcc atagatttcg atgatacgtc
     1261 ccttaggata accacctgag ccaagggcaa tgtcaagagc taaagaacct gagctcatca
     1321 cttgcacctt ttgctccgca cgttcaccca aacgcatgat tgatccttta ccaaagtctt
     1381 tctcaatcaa tttaagagcg tcattcaagg ccttttcacg ttctgcccca aatttttttg
     1441 aaatttcttc taattttttt ggttttttcg ccattctatt ctcctacatt ctaatgatcc
     1501 tcagacctat ctactattat atcaaaaatt agtcacttaa taaagccttg cgaactaggt
     1561 taaaggcatg cataaccgca atgtgacgta catctgctcg gcttctgcct ccaatattaa
     1621 ccttgataac ctcagttcct tgatcttgcg ccaagcctat gaagactgtc ccaactgggt
     1681 gtccttctag gctatctggt cctgccactc cagtcaaact aattccaaaa tcagactggg
     1741 tcttgcttcg tgcctgctca gccatcttct gagctgtaaa ttcagacacc acaccatgtt
     1801 cttccaaatt cttggcagga atatccaaca tccttgattt ttcctccaag ctataggtca
     1861 caaaaccacc cttaaatata cttgaaattc cagaaaaatt cgccacggta gcttggaaaa
     1921 gacctgccgt caaactctct gcagccgcga tggttttccc ttgccttttc agttcttcta
     1981 ccacaatgct ggctaaacta gtttcttccc cataaccata gcaaaagtct cgtaaagaaa
     2041 ttccttcgaa agtctggcag tccaagattt gattttccaa gatatccagc gcttgattcg
     2101 cctcttcttg actgctagcc tttgttgaca gacgtagagt gacttctcct gtcttggcat
     2161 aaggggccaa ggtaggatcg acctgattat caattaaatc agccaaaatc gtaaccagct
     2221 ggctctcgcc aatcccaaag aaacgaagaa ctcgggaata cagcttgctc cctgtcatca
     2281 acttgggtag aagtaggttt aagaccatgg gtttcaattc acttggcgga cctggaagga
     2341 cgacataggt cactccgtct acttctaatt ttcctccaac agccagtcct gtttcgtttg
     2401 gcagtggaat cgctccttct acaatttgag cttgtctttc gttattcggt gttcgggcat
     2461 agtctggtcg cagggcaaaa aagatatcca acttctcctg agcctgagga tcaaagacta
     2521 atgctttccc taaaaattta gctagggttt gtttggttag gtcgtcctca gttggcccca
     2581 aaccgcctgt caaaatcacc agactgctac gttgactggc aatctcaagc aaagacaaga
     2641 gacgaacttc attgtctcct acagccgtct gaaaatatac atctacccca atctcagcta
     2701 gtttttccga caaaaactgg gcattggtgt tgacaatctg tcctgtcaaa atctctgttc
     2761 caacagcaat gatttctgct ttcatgtttc ctcctaccta tctattcgta tttttttgaa
     2821 aaaatcgcag gaattttcct acgattgatt ttttatttgt atcaaaagtt aattatcttc
     2881 atcaccaaca ggtgctctgc caaataaatc ttcaaataaa accgcattgg tttcaagctg
     2941 agtaacttct tcttgtccca aagaacgtcg gagtatattt tgcatttcca acatatgtgc
     3001 tcttgaaaca atctggtaag aaacaccttg aagtatctct ccttcaccct gcaactgctg
     3061 agtttcaatg gttttaaatg aatctttata gcctagcaag ttagggatac tttttgcaga
     3121 caaatcaata ttggtctgca tattgtcact caaagctttt agaatctctt gataatgacc
     3181 aacgctattt aaactgagag ctttttccat gactttttga ataacttcac gttgacgttt
     3241 ttgacgacca taatccccct caggatcttg gtaacgcatt cgtgcataga ctagggcttt
     3301 ttctccccca atatgttgct ccccaacacc gatagaaata gtattaaatt cttcttggtc
     3361 actgatagaa attgggaaac ctaggatatt attgactgta atacctccta ctgcatccac
     3421 tagtttttgc aaccctctca tattgaccat cacatagcga tcaatatgga tattcatcat
     3481 tttttgaatg gtttctatag caagctctgc tccaccatct gcatatgctg agttcagttt
     3541 cgcttcatga gcctgaccat tccctgattc aatgcgcgtc agaatatccc gctctaaact
     3601 catcattgtt gtttttttcg ttttaggatt cactgtcatc aagatcatgc tatcacttct
     3661 accgacccaa gtttcagttc gttcaacatt tccggtgtcc actcccatta acagaatggt
     3721 tagaggttca gtcgcttcaa taaccttggt ttcttcgccg atttttttat aggttttagc
     3781 taaggtttct gtcccttgtt gataaatagt ataagcaaaa acacctactc ctactacagt
     3841 tacagaaagt aaagctagca ccattccaat aattttttta accatatttc tactaaccta
     3901 tcagtttacc catcaagtaa acatcgataa atttcccttc ttctatatat gccccacgct
     3961 cttggctacc ttcaatgaca aagccatgct tttgataaag atggactgct gcttgattac
     4021 gagtttggac agtcagttgg agacgacgca gaatgccact tgcttgtgcc cactctatcg
     4081 cttcttctag caacaaactt cccaagccat tattccaata tctttttcca atcacaatga
     4141 agagatctcc aatatgacgg actctcttac gctgatcagc tgtaatattt acaataccag
     4201 caattttgcc atttaagaat gcaagtaagg ttatctgatt gtccgaacta gcttgcttgt
     4261 tgaggaatat ttccatctcc tcactagtca agagaatacc atctccgtct aggctggtaa
     4321 agtctgtctc caaactcaca cgatttaaaa aggccactaa ttcagctgca tctttgggct
     4381 ctgcttccct aatgagcaat tcatactcca tattgaagct cctctaacaa tttctcagca
     4441 cgcaaaccct ttgcctgaaa atttaaacgg cgtccatctg cttcttttag aatttccaat
     4501 tctaaataag catctggcaa ggcatctcct aagagatttc cccactcaat aacagtcacg
     4561 ccgccaccaa agataaactc atccaagtcg atagaatcag catctccttc aatacgataa
     4621 acatctaggt gataaagtgg aagtcgacct tcatactctc tcacgatagt ataggtggga
     4681 cttttaatca tttgagaaat ctgtaatcct tttgcaagtc ctttagtaaa ggtcgtttta
     4741 cctgcaccca gttctccagt taagattaaa acatcattct ttgctaatag atggcccaaa
     4801 cgctccccta aggcttgcaa ctcttcttca ttttttgtgt acatactctt attataccaa
     4861 aaacttttct tttgtgtcta ttttcctact aaacttatca tcataacatc cataaaaaac
     4921 aggctttctc taaaagaaaa tgagcgtaac aatgaccaat acaagatctc ggaaaatatg
     4981 accataaaag gaaacttcct tcttaaccga atttgggaca agataggctg caaaaaacaa
     5041 gcccagtcca atataaatca gaagtgagac aatggtcatt ggatttctta agaaaagaag
     5101 tgttgctaaa atagtcacca acactgtctt ttttctgtct agcatagcaa gaaaatcgcg
     5161 cacgtatttt ttcaagggta aaaaaatcag caaatctagc ccaaatagga aaaagaagga
     5221 tggcaataaa aagtcaacta attcttgctg cagcgtattt ttgatgaaca agttatctga
     5281 caaaacaaga acagctccta acaaattaat taagagtaac atactgtaaa aaagcttcac
     5341 cgacttctta ctggctagga cactatggac ttcttgctta cgggtataaa gataatttac
     5401 tccagcacag attcctgaaa cgaaaaccat gctcccgatg aaaaaagctg tactttgttt
     5461 aaaggacaag atgcattcct tccataggaa acagctactc aaactgattt gaattaaagc
     5521 taacaaaaat aagattctca ttgatttcat cttctctctc ccttcctacc aatcattata
     5581 ctaggagaaa agagagaact gtttctaatc ttctcaaatg tctctttaag acgctaaaca
     5641 aacactagag actaatactc aatgaaaatc aaagagcaaa ctaggtagct agccacaggt
     5701 tgctcaaaac actgttttga gattgcagat agagctgacg tgatttgaag agattttcga
     5761 agaatataaa tttgaaatca tgaaaatccg tcaaacgggt ggttgttttg tctcgcacct
     5821 cacggagcga gacggactca gagtcacata attataaggc tgatagtatt aatctaacta
     5881 tcagccttac aggttattta acgtttcaga aaaactataa tgtcaagatt aactaaacag
     5941 tatctaattc cttcaaataa ttttctatct tcatcagcat taaaggattg ttataaatct
     6001 tgcatagctc tcttgcttct atataataat ttttgacttg ttctctgtct agaaatttgg
     6061 ctccagcatt tcctacaaga ataagtagag gagccaattg gtagcttgtc tgtctttgtt
     6121 tacagagttc gatagtctca agagcttctt ggatggcttc attatatttt tcctttgata
     6181 ctaggtagtg agcgtaattg taacgaactc tgatgtagcc aaataaaaac tcttgatgct
     6241 caaaattttt tgtctgatat aactccatca aatgagagta gtttacctca tattcttgtt
     6301 cacgacccac taaggaatag aaattagata gagtattcaa cgcctttaaa taaatcaaag
     6361 tatttgagga gacttttaat aatatatttt ccaatgaaga aattgcttca cacttactgt
     6421 catattgaca gaagtcaata atagctttaa tccattcaag gtaagttcgg tcttctagtg
     6481 ttagaaaagt acttcgttca atctctattc tataaatata ttccaaattt tcataatttc
     6541 tatcatctaa taggcgagca gataattgct tgaaattaga gaggttagat ttaatttcaa
     6601 tttgttcatt aaaaaaataa tctaatggca cttcgagtcg ttgtgagagt ttgaacaaaa
     6661 ggtctgcgga gggaatgaaa taccctctct caattttact aatctggctc tattcacaaa
     6721 ttccttctgc aagagtttgt tgggagagtc tcaactcttt tcttttcaat ctgaatttct
     6781 ctgcgagtgt attcattaaa gataataaac cttcctattt gcttaatttc attataaaat
     6841 ttttagttca aaatagcaag ttaaaggaat aaataattct ttgcggtaat aaacaaaaaa
     6901 aagtcaaaaa ttacataaaa atgcttggct aaataaaata tatttgttaa aataaggata
     6961 atgaaaaaga aaagggtttc acgaatgaag aaaaatcgtg gaattcaaaa attagctata
     7021 ttagtattac taggtgtttt tatgtttagt aacacaattc cttaccaaca gtttattcag
     7081 aagaatagac aattggagat tcgagtccaa tcgcaaaaga agtccaatgg tcttgatgtt
     7141 gggaaggctg attgatttta tattacttta aaattcaact atttagagaa aggtattctg
     7201 atgagagctt gtaacaatac cagatagata taagaatgga gatgtttgat aaaatgcttt
     7261 catagctaac caactgttga aaattatgag ttacaaaatc taaagtattt aagattggtt
     7321 tataaaatta ggtctctgcc tgtagaaagg aacgtgcagt tagaaaggag gaaaaaatag
     7381 gatactataa ttcagactga gatttctaat taaaatatat agttgcattt cgctcatttt
     7441 cataatattt cattcagagg agtaataata tgttaaaatt tagaaaagta gttgcatcat
     7501 cccttgccgt tttggcattt agtttggctc ttcctgtttt ggcagtttct caccgtggtg
     7561 gcgagtggac ctatggaggc catcatgatc caaataattg gggagcattt tcgaattatt
     7621 atcatggttc acagtatcac tgggcctatg ttggaagtaa tggacgtaac aatcaaaaaa
     7681 cagtttatgc aggagcacgt agtgcggcct atgcgtttgt taatacaaat tttggggagc
     7741 aagttacatt tgatgcggga tggtaaagaa taattgaaga agattctttt atcaatagtt
     7801 cagtaagctt gttagtttat agagggcagg ggtatttctg ccctctgttt tagaataagg
     7861 aatgcactat gaaaaaatta tttatactca tatccaacct gcttgctagt ttgttctttg
     7921 tttgggtatt taccatttgg actgatacat atgtctccta ttattacccc aacgttgttg
     7981 tacatgattc ttcccctgaa acaacttttc agcatgttgc tacacgcttg gaaaaactag
     8041 cagaagaaac agatagcttt attgcgattc aacaccaaga tcctaactca gaaggtacta
     8101 cagttttttc ttatacgacc tttggggacg gaaagttgcc tgatgggctt caggaaaaaa
     8161 aactagaaga tgctcaaagt agtagtgttg aaacaaacta ttttgtattc gatggacacc
     8221 tagatattca cttgctaagg gaggagctaa gtcaacttgg cttgactaac atgaacctga
     8281 caattccatc taaactatct acgttaatgg ctatctttag taacggattt cagttaatca
     8341 gtctattgat tttcatctta acctttatag cactgacttt aattagtcaa attagccaat
     8401 tacggtcgtc gggcattcgc ctcatttcag gagagaaacg gtggtccatt ttccttagac
     8461 cagttggtga ggatttgaaa gggatagctg ttggtttcag tttagctggc gtgctcgcca
     8521 ttcttatgca aaaaattctg tcgcttccaa cgcaatccct aatgaccata ggagcaggct
     8581 tgctcagtta taatctcatc ttgttgtcga tctccctgtt tttcgctcaa ctcttcgcag
     8641 ttgggataaa aaagatacac ctgatgcaga ttataaaagg gcaagtgcct gtcagaggaa
     8701 tcattagttt gattttaatc ggtcaactat tagcgattat tattgtaacg ctgggaatag
     8761 ggagtagctt aaagtattcc caagcctggc aacagcatcg gattggacaa gaggcttgga
     8821 gtcaggaaag gcaactgatt accctatcaa tcagccgtga aggaacgagt cctggttttg
     8881 atgaacaagc tcaaaggaaa ctcagaactt ggtatcaatt gatggatctg gctgtttcag
     8941 aacaaaaggc tttcttatct agacaccagt taattgaccg tactttgcaa aatggcatgg
     9001 cttcctccaa aaacttgata acctctacag aatggcacga ttacaacccg aatggcaatg
     9061 tccttatcgt cacaccgcaa tacttggagc gtcaaaacat tcctgtagat acaactattg
     9121 agcaaaagat gaatcacctt gatgtagggg agtttgtctt attgctgcct gaacacctcc
     9181 gttcagagga agaacattat aaatctgttt ttgaagacga cttaaccagt cgcatgtcta
     9241 gtcaagatga acgacagcaa atgactgcta cggtaggtta tttagaatca ggtcaggatc
     9301 gttttgtgta taatacgacc cctatttctt accagcagtt tttgaaagat ccaatcatca
     9361 ttgttataac accccaatca actggtccac agtccatttt gttttggata gacgcagtac
     9421 agaactacgt tctctttaat caattgtctg atgcccagga gcttatccag agacaaggca
     9481 ttgaaaattg ggtctcagaa atgcaaacag gttaccacaa ctacatcaca ttattggata
     9541 atattcagag ggaacgttgg gtaatgctag caggagctgg gcttgggatt gcaacttcaa
     9601 tcttgttgtt taacactatg aataggctct actttgaaga atttagacgt gccattttta
     9661 tcaaacgcat tgcaggtctc aggttcttag aaatccatcg cacttatctc tttgctcaac
     9721 tgggtgtgtt tttactggga tttgttgcga gtgtatttct tcaggtagag ataggagttg
     9781 ctttcttagt cttgttactc tttactggtc tatctctttt acagttacat gtccaaatgc
     9841 agaaagaaaa caagatgtcc atgcttgttt tgaagggagg ttaatatgat tgaacttaaa
     9901 caggtgagta aatcttttgg agaacgagag ttattttcga atctttcaat gacatttgag
     9961 gctggaaaag tctatgcctt aattggttca agtggtagcg gaaaaacaac cttgatgaac
    10021 atgattggga aattagaacc ttatgatggg acgatttttt accgaggtaa agacttggcc
    10081 aattataaat cgagtgattt tttccgtcac gaattgggct acctcttcca gaactttggc
    10141 ttaattgaaa accaaagtat tgaagaaaac cttaagctag gtctcattgg tcaaaagttg
    10201 agtcggtcgg aacagcggtt gaggcagaag caggctttag aacaggtcgg cctgacttat
    10261 cttgacctag ataagcgcat ctttgagtta tcgggcggag aatcgcaacg ggttgccttg
    10321 gcaaaagtta tcttaaagaa tccacccttt attctggcag atgagccaac agcttcaata
    10381 gacccagcaa cttctcagtt gattatggag attctgctat ctcttcgaga tgataatagg
    10441 ctaatcatta tcgcaacaca taatccagca atttgggaga tggctgatga agtgttcacg
    10501 atggatcgtc tgaaataaaa atccttgttt ttaattgcac gatgagttac tgaaatatta
    10561 tcatgaatca ataattggag ttaatttaga attgtacttt attaatattg aggtaacttt
    10621 ttcttgataa aggaagaaat agtggagagg aagttagaat gaaaaaattc gacaattata
    10681 ttgttgagaa gccttgcgat tctaattcag ataaactgca aaaaatctta ataattgaaa
    10741 atttggtaga tgatattttg caatttcctc tcagaatcaa taatagtgta ggagagattt
    10801 tcctcctaca accgtttcaa aagaaaacta tctttattcc atgttatttt gaggaagata
    10861 ttgtgaaagt caaagatgat gataaagttg agtggaattt gttagaattt caaaaattta
    10921 gagcattttt ggcttagtaa tctgtgttga aggctcaaaa cctatggtaa aaaagtcgct
    10981 ttgaaaacgt attgcctcca aagatttagt taaataatga tttaacacaa aaagaaatta
    11041 ttgaagttct ggaaagatgt tgtttcagta ttgagaaaag gtgggaaaaa cttgcgattt
    11101 tcacagagaa aggaagaaaa agtatagaaa tatagtcaat tgaaacaaga acaggacaaa
    11161 agaacctttt gtgccatatt tttctccttt cgctttacaa ttggcttgaa cacctttatt
    11221 gtatcgcgtt tggagttttt ttggtataac cttcgacgcg cacccgcata gcgggtgttt
    11281 ttttgtctcg cacctaacgg agcgagacga actaatagtc acttaatcaa aaaacgcacc
    11341 atatcaaaaa ctaaaaagtt tgatatcatg cgtcatgtct taaactaatt gactatactt
    11401 tctattcaaa tgagctttta accaattgat tgagccaatc cactcttaaa accaaagagc
    11461 aatttctcgc ttagctgact cttctgaatc tgaaccatgt acaacatttt ggataacctc
    11521 attttctcca gcagcttttg caaaatcacc tcgaatagtg cctggtaaag cttcttctgg
    11581 acgagttgca cccatcatgg tccgccaagt ttcgattact ttgggaccag aaatgacacc
    11641 cacaagaact ggacctgaag tcatgaattc acgaatcggt gggtaaaaac tctgaccaac
    11701 caagtcctga tagtgctggt caatcaactc ttctgaaact tgtgaacgaa actccaattt
    11761 ttcgattgta aatccacgtt gttcgatgcg ctttaacact tcacccacta gccctctttt
    11821 tacaccatct ggtttgatga taaagaatgt ttgttccata cccgtctcct ttgtcagctt
    11881 ctttctttta ttttaccaca tttcgtggaa aaatggagaa agttttcaga atagagaatg
    11941 agagaacccg agggttctct cattctctat tattctactg tttcttccac agtttcaacg
    12001 gcagtatcca caactacttc tgttgtttct tcatttcctt cttcctctac tggaggatta
    12061 aggtattctt cttcgttgac agcatatggt tcaaggttac ggtaacgggc cataccagta
    12121 ccagctggga tgatcttacc gatgataaca ttttctttaa gtccaaggag atggtctttc
    12181 ttaccacgga tagctgcgtc agtaaggaca cgagttgttt cctggaagga agccgctgac
    12241 aagaaactgt ttgtttcaag tgaggctttg gtaattccca taaggactgg gcgacctgtc
    12301 gctggaactc cacctgcgat aaggacatct ttgttggcat ctgtaaagtc attgatatcc
    12361 atgagggtac ccatgagaag atctgtatca cctggatcca tgacacggac tttacggatc
    12421 atttgacgaa ccattacctc gatgtgtttg tcaccgattt ctaccccttg gctacggtaa
    12481 actttttgta cttcaccgag aaggtacgtt tcaactgaca agacatcacg aactgcaagg
    12541 agacgttttg gttggataga accttctgtc agagcagcac cacgcgctac ttggccccca
    12601 acttcgacac gcatacgagc tgtaaatgga acgacatatt caccttcgcc agtttcaccc
    12661 ttaacaaaga ctttcttggt acgagttgat gcatcttctt cgatagcagt aacttctcct
    12721 ttaacctctg tgataaccgc ttccccttta ggattgcggg cttcaaagat ttcttggaca
    12781 cgaggaagac cctgagtgat atcggtattt gaggcaaccc cacctgtgtg gaaggtacgc
    12841 attgtaagct gtgtaccagg ttccccgata gattgggcag caatggtacc aactgcttca
    12901 ccaacttcaa ccgcatcacc agtcgccaag ttgataccgt aacagtgacg gcagacaccg
    12961 tgacgagtgt tacatgtaaa tacagaacgg atagtcactt cttccacacc agcattgaca
    13021 atttcacgcg ccttgtcttc tgtaatcaat tcatttggac caataatcac tgcaccagtt
    13081 tctggatgtt taacagtttt cttagtgtaa cgaccgttga gacgctcttc gagagactcg
    13141 atcatctctt ttccttctgc gatagaacgg atcaagagac cacggtcagt tccacagtcg
    13201 tcctcacgga tgataacgtc ttgggcaacg tcgaccaaac gacgagtcaa gtaacctgag
    13261 tcggctgtct taagggccgt atcggtcata cctttacgag caccgtgagt tgagaagaac
    13321 atttccaata ccgacaaacc ttcgcggaag tttgaaagga ttggcaattc catgatacgt
    13381 ccattcggag cagccatcag accacgcata ccggcaagct gtgagaagtt tgagatgtta
    13441 ccacgggctc cagagtccat catcataacg attgggttct taggatcttg gttagcaatc
    13501 aagcgtttct caagtttttc acgggcagca cgccattcag ctgtaacagc attgtaacgc
    13561 tcgtcgtctg tgatcatacc acgacggaat tgtttggtga tttgctcgac acgtttgtgt
    13621 gattcttcaa tgatttcagc cttgtcatca acgactggga tatcggcaat acccactgtc
    13681 aatcctgcaa gagttgagtg gtggtaaccg agattcttca tgcggtcaag tagggcagaa
    13741 gtttctgtcg tacggaaacg tttgaagatt tcagcgatga tatttccgag gtttttcttc
    13801 ttgaacggag ggttgagctc aagattgctg atagcttcct tgatatctcc accaagtggc
    13861 aagaagtatt tagctggaac accttctgtc aagttggcat tgtttggttc ttgcaagtat
    13921 ggtagcccct ctggcatgat atcgttgaag agaattttac caactgttgt aagcaagacc
    13981 ttatgtcttt gctcttctgt ccaaggcttg ttgaggctgt ctgttgcgat accaacacgt
    14041 gagtggaggt gaacataacc attgcggtaa gccataaccg cttcgtcacg gtctttgaag
    14101 accattcctt caccttcgcg accagcttct tccatggtca agtagtagtt acccaaaacc
    14161 atgtcctgag atggagtaac taccggtttc ccatctttcg gattcaagat gtgctcagca
    14221 gctagcatga ggatacgagc ttctgcttgt gcttcttctg aaagtggtac gtggatggcc
    14281 atttggtccc cgtcaaagtc agcattgtag gcttcacaga caagtgggtg caagcgaaga
    14341 gccttaccat caatcaagac tggctcgaag gcttggatac ccaaacggtg aagggtcggt
    14401 gcgcggttca aaagcactgg gtgttcttta atcacttctt caaggatatc ccagatacgc
    14461 tcatctccgc gttccaccaa gcgtttagct gctttgacgt tttgcacgat atcacgggca
    14521 acgatttcac gcatgacaaa tggtttaaag agttcaatcg ccatttcacg tggcacacca
    14581 cattggtaca tcttaagagt tggaccaacg gcgataacgg aacgtcctga gaagtcaaca
    14641 cgtttaccga gcaagttttg acggaagcgt ccttgtttac ctttaagcat gtggctcaat
    14701 gatttcaatg gacggctacc tggtcctgtg attggacgac cacgacgacc attgtcaatc
    14761 aaagcgtcaa ctgcttcttg aagcatacgc ttctcatttt gaacgatgat acctggtgca
    14821 tttaactcaa gcaaacgagc caaacggttg ttacggttga taacacggcg gtaaaggtca
    14881 ttcaagtcag atgaggcaaa acggccacca tccaactgca acattggacg aagatctggt
    14941 gggataaccg gaagaatgtt aagaatcatc cattcaggtt tgtttccaga cttgtaaaag
    15001 gcatccaaaa catccaaacg acggatggct ttgacacgtt tttgtccagt agctgttttc
    15061 aattcttctt tgagttcagc aatttctttt tcaagatcta cttgcttcaa aaggtcttgg
    15121 atggcttccg cacccatctt ggcaacaaat gaaccataac catattcacg caagcgctct
    15181 cggtattcgc gctctgtcat gatagacttg tgctcaagtg gtgtatcctt aggatcaatc
    15241 accacataag ccgcaaagta gataacttcc tcgagggcac gagggctcat atcaagggtc
    15301 aagcccatac ggcttggaat ccccttgaag taccagatgt gagatacagg agctttcaat
    15361 tcgatatgtc ccatacgctc acgacgaact ttcgtacgcg ttacttcaac cccacagcgg
    15421 tcacaaacaa ttcctctgta acgaatgcgt ttgtacttac cacaagcaca ttcccagtct
    15481 tttgtaggac caaagatcac ttcatcaaag agtccttcac gttctggttt caaggtacga
    15541 taattgattg tttcaggttt tttgacttct ccataagacc atgaacggac tttacttgga
    15601 gaagctaggg tgatttgcat acttttaaaa cgatttacat caaccactat ttcttccctt
    15661 tctattctaa gtgaactgct tattcttgtt cagcagcttc ttctgttgct tccgcttttg
    15721 ttgctttctc agcttcttca gcttcaaagg ctgctttagc ctcttgagct gctttttcgc
    15781 gggctttttc aaggtcatct acgtggatga catcttcgtc cattccttca tccaagtcgc
    15841 gaagttccac ttcttggtca tcttcgtcta ggacacgcat gtcaagacca agagattgca
    15901 attctttgac aagaactcgg aaggattctg gaacacctgg ttttggaatt ggtttgcctt
    15961 ttgtaatagc ttcataggct ttcaaacgtc cgttgatatc gtccgacttg taagtcaaga
    16021 tttcttgaag gacatttgac gcaccgtagg cttcaagagc ccaaacctcc atctcaccga
    16081 aacgttgtcc accaaactga gctttacctc cgagtggttg ttgggtaaca gttgagtaag
    16141 gtccgactga acgcgcatgc aatttatcgt caaccatgtg gtggagtttg atcatgtaca
    16201 tgactccaac agaaacacgg ttatcaaatg gttcacctgt acgtccatcg taaaggattg
    16261 tcttggcatc gctatccata cctgcttctt taacagttga ccaaagatct tcagaacttg
    16321 ctccatcaaa gactggtgtc gcaatgtgaa taccaagagt acgagctgcc ataccaaggt
    16381 gaagctccat aacctgaccg atattcatac gtgatggcac cccaagtggg ttcaacatga
    16441 tgtcgactgg agttccgtct ggaaggtaag gcatgtcttc tacaggaacg atacgagaga
    16501 caaccccttt gtttccgtga cgtccggcca ttttatctcc gaccttaatc ttacgttttt
    16561 gagcgatgta aacacgaacc aacatgttaa cacctgattg caactcatct ccatttacac
    16621 gtgtaaagat cttaacatca cgaacgacac catcggcacc gtgtggtaca cgaagagaag
    16681 tatcacgcac ttcacgagac ttgtctccaa agatagcgtg caagagacgt tcttcagctg
    16741 aaagatcttt ctcaccctta ggtgttactt tacctacaag aatatcacct tctttaacct
    16801 cagcaccaat acggataatc cccatttcgt caaggtcttt gagggcatct tcaccaacgt
    16861 ttggaatttc gcgagtgatt tcttcaggcc caagctttgt atcgcgcgtt tctgattcgt
    16921 attcttcaag gtgaacagat gtgtagacat cgtccttcac caagcgttcg ctcatgataa
    16981 cggcatcctc gaagttgtaa ccttcccaag tcatgtaggc aacgattggg ttttgtccaa
    17041 gcgccatttc tccattttcc atagaaggtc cgtcagcgat gaaatcgcct ttttcaacga
    17101 catcaccaac ttttacgaga gtgcgttggt tgtaagcagt acctgagttt gaacgacgga
    17161 atttttggat gtggtaaaca tccaatgaac catcttcacg acgaacttct accttgtcag
    17221 catctgcgta agtaacttta ccatcatact gagcaatcac agccgcacca gaatcgtggg
    17281 ctgcttggta ttccatacca gtaccaacgt aaggtgcctg aggattaatc aatggcacag
    17341 cctgacgttg catattggct cccatgaggg cacggttgga gtcatcgttt tccaagaaag
    17401 gaatacatgc tgtcgcaacg gcaactacct gttttggtga aacgtccatg tagtcaacaa
    17461 tattagctgg atactcttgg ttgacccctt ggtgacgtcc catgacaatc ttctcagcaa
    17521 aggttccatc ttcattcaga ctagagttag cctgagctac agtatattca tcttcttcat
    17581 cagctgtcaa ccaaacaatt tcgttcgtga caacacctgt ttcacggtca accttacggt
    17641 atggtgtttg aacaaaacca tatttgttca agtgtccgta agatgacaag ttattgatca
    17701 aaccgatgtt aggtccttca ggtgtctcga ttggacacat acgaccatag tgagtgtagt
    17761 gcacgtcacg tacttcatat ccagcacggt cacgagtcaa accaccaggt cctaaggctg
    17821 acaaacggcg tttgtgagac aactcagaaa gcgggttgtg ttggtccatg aactgtgaca
    17881 actgtgatga accaaagaat tctttaactg cagctgttac aggacggata ttgataattt
    17941 gttgtggtgt caagacttca ttgtcctgaa cagacatacg ttcacggaca ttacgttcca
    18001 tacgagaaag tcccaaacgt acttggttgg caagcaattc accaaccgca cggatacgac
    18061 gatttccaag gtggtcgata tcatctacac ggccaagtcc ttcagccaag ttgaggaagt
    18121 agctcatctc agcaaggata tctgcaggag tcaccgtacg aaccttgtca tctgggttag
    18181 cattaccaat gatcgttacg acgcgatctg gatcagttgg agcaacaacc ttgaattttt
    18241 gaagaacaac aggctcagtc acaacggctg catcgtttgg gatgtagaca atcttgttca
    18301 agtcgccatc caaatggctt tcaatgcttt caatcacgct acgagtcata atcgtaccag
    18361 cttctaccaa gatttctcca gtttcagggt ctaccaatgg ctctgcaatg gtttggttga
    18421 gcaaacgtgt tttaacattg agttttttat tgattttgta acgaccaact gctgccaagt
    18481 catagcgacg tgggtcaaag aagcgagcca caagcaagct acgtgagctt tcagctgtct
    18541 taggctcacc tggacgaagg cgttcgtaaa tttctttcaa ggcttcgtct gtacgagagt
    18601 ccattggatt cttgtggata tctttttcaa cagtgttgcg aaccaattcg ctgtcaccaa
    18661 agatatcaaa gatttcatca tcacctgaga aaccaagagc acgaaccaag gttgtaaatg
    18721 gaatcttacg agtacggtcg atacgagtgt aggtgatatc ttttgagtcg ctttcaagtt
    18781 ccaaccaagc tccacggtta gggataacag ttgaaccata gcccacctta ccatttttgt
    18841 ctactttgtc gttaaagtaa acacctggtg agcggaccaa ctgagaaacg ataatacgtt
    18901 caccaccatt gatgatgaaa gtacccattt ctgtcatgat tgggaaatca ccaaagaaaa
    18961 cttcttgggt cttgatttcg cctgtttctt tattgatcaa gcggaaggtt acaaaaattg
    19021 gtgctgagta gctagcatcg tggatacgag cttcttctag cgtgtatttt ggttccttga
    19081 tttcatatcc aacaaattcc aactccattg tgtctgtgaa gtttgaaatt ggcaatacat
    19141 cttcaaacac ttccttaaga ccgtggtcta ggaaagcttt gaatgagtca gtttgaattt
    19201 caatcaaatt tggtaagtca agaacttctt tgattcttga aaaactacga cgggtacgat
    19261 gtttcccgta ttgaacgtca tgtcctgcca agatgattct cctttgtaaa taagttccaa
    19321 gccttgtcaa tcaggctttt ctaatcgcca tatggttgta aaccccttat caccgtgtcc
    19381 tcttgacgaa ttttcagaat ctttaagcct ctgttacaaa tgctcaaaat cttgaaaaaa
    19441 agcacaaaaa gagcagctaa atctgacttt ttcagaagat ttaactgctg tgagccttgt
    19501 ctggacaata tttcagacaa aacctacgac aaatgattac ccatattata ccctatttag
    19561 ctagattttt caaggggatt cagtaggttt ttggtaattt ttttcccata gaaaacttgg
    19621 catcacattc gaatcacgct atggtacaaa aaactgaaaa aactattgac tgaaaatcat
    19681 tttcaaggta taataataaa cgttaaggcg gtatagccaa gtggtaaggc acggctctgc
    19741 aaaagcttga tcgtcggttc aaatccgtct accgccttct ataacttgat ttatcaggtt
    19801 tcaaatgaac agaaagccca atttgaaggg ctttttttat tttccctcga ataaatacgt
    19861 ataactttaa aaacttttgg agcgagtttg tggcagagtt ctttccatgg cataattccc
    19921 ttttgaaatc aattgaaaaa agcttcgtca cgcctggtga caaaagcctc tagtttattc
    19981 tgtttcttct tctatttcga cttctgtgat ttggactttt accttggtaa cacgtccatt
    20041 cttcacttta tcattggtta agataaactg tttgttttgg ctgaccaatt catagctgag
    20101 tttctcagtc gttggaatgg ttcccactcc tgtcaaataa taaccagcga tagtatcaac
    20161 gtcatcactt tccagttcaa cattaaagta attattgaaa tcattgaggg tcatagttcc
    20221 ttgaacaatg taggtatcct cgccaatctg atgaacatct attgctgctt tgtccgtttc
    20281 atcatcaatt tcaccaacaa tttcctctaa gaggtcttcc aaagtcacca aaccagccat
    20341 accaccgtat tcatccagca agattgccat ttgtctttgg gtatttcgca gttcttttag
    20401 caagtcatcc acaaaaatag tttcaggtac aaaaagtgga tcttgtaaaa ttctcttcca
    20461 aacaatattg tcaaaaccgt ccacaaagcc tgccttaagg agactcttgg tgtgaatgat
    20521 tccaattaca ttgtccttat ccccatcata aaccgggata cgagaataat tttgttttaa
    20581 aatactttgg ataatggctt gactatcatc ctgaatatcc accataaagg catccgttcg
    20641 aggaaccata acctctcgtg ccatcagttc atcgagcgaa aagacacctt gtaacatctc
    20701 aatctcatca gcatccaatg tttcttcact atttgtcagc atataggcaa tttcatcacg
    20761 ggtcatcttt tcatccgcat catcgaatga cataggagtc aaatggctca agaaattggt
    20821 cgaagcagct aaaagccaaa caaaaggact gactagtttt ccgatcccaa tgataaccgg
    20881 cgctgtacga attgccaagg catcctttag attaagagcg attctcttag gatataattc
    20941 cccaaaaacg atggaaatat aggtcaaaaa tgccaaggat agaaaagttg ccacggcttg
    21001 tgctgtttcg ccattcccaa gccaagaggc aatcacacgt cctagagtat cagttaaact
    21061 cgcccctgat aagattgtaa tcagggtgat tcctacctga atggttgata aaaagtggtt
    21121 aggattttct agtaccttca gcaggcggat gtagcgtctg tctccttctt ccgccttttg
    21181 ttcaactcgg gcacgattaa gagaaaccat ggccatttct gtggctgaga aaaaggcatt
    21241 taataccgtc aagataaaca ataaaacaaa ttgtagcaac aaattctgac tacttgggtc
    21301 ttccatagtt cttctcctaa aatagtatct tatcctttat tatatcacaa aatttaatcc
    21361 aatacatatt atttttttct tagcgtaact tccatctctc tcccaaaact ggaagttagt
    21421 ctaagacgga tttccactga tttcacgcgt ttttctcata ctaaaagcta ggttgtggga
    21481 aactggaagt tagttttaga agttactatt ttttcttagt acctgttcta gccctgctta
    21541 aactagtaaa aagaactcct acatccataa gtgacatagg agtttaggct tatcttttac
    21601 tgagttacag ttacttctcc agttcggtaa tccagttgaa gtcccttttg aacattggga
    21661 actagaacat tgaattccaa ttctccatcc gaagacttgg cttcaatctg tgaagctgag
    21721 ggaactaaat cctcgtttga agcgtagtaa agggttacac ggtaacggac acgcttgttt
    21781 tggtccaagg ctttacgcac cttgctttca tagtagtttt gaccagtcga atactcggct
    21841 tgtgcctgat ttgcccaggc tgtctgaaca gcaatgtttt taggattgct tgttgaggca
    21901 tcaaaaccat ccaaaccacc gattaaggca tagcctaaca aatgacctct atcgactgca
    21961 tgggtataag agccctttag attcttgacc tgatgccaac ctggaggagt ccaagaagtt
    22021 gaaccattcc cagtttcttt acgattcttg tactgacgag tggccttaga caagagggca
    22081 ttagctacgg ttggaacagt ttccttaccc actgtctttg ttttattgtc agcgtagggc
    22141 ttacttgaaa ccttggcatc tagatttgtt ttattaccat tgacgataaa agcacctgag
    22201 ccattccact ccagactccc ctttatttga ctcttgactg cgtctgttaa gacactctct
    22261 gccaatgctt gactaggagc ttcaggcgct tgttttttct gactaagctt ggttttagga
    22321 ctattagctg tcgactgcat ctgcttgata taatagctcc ctgtagacaa aagcaataac
    22381 actagcagtc cgattagtgt ctgtcttgtt tttttgttca tatttctcct tatctttaga
    22441 aaaaggctgg ttctccagcc taatttcctg taaatttatg aatcaattcc tgccattttg
    22501 ctggagacag gatagcccat gaatcttgac ccttgcccaa gattccataa cctaccatta
    22561 aaccgattcc tagagccaga gtacctaaaa tcagtactat gatgactaaa agtaaacgct
    22621 tgactacgta gcttgatttc ttattcatct tcatcacttg cctcaatccg ctgaatctta
    22681 gcacctagct gcgccaactt ctcatggaaa ccgtagtaac ctctatccaa gtgaaccaat
    22741 ttaccgacca cagtttctcc ctgtgctacc aaacctgtca aaatcaaagc tgcactggca
    22801 cgaaggtcag ttgaaagaac ttctgctccc tgcaaaggct gtccaccaac aatacgagct
    22861 gtatcacgga taatctcaga atgcaagccc atgcggcgca tctcttctag gtgttggaaa
    22921 cgattttcaa aaactgtctc caccatggtt gattcgcctt ttgcaactgt catcaaggct
    22981 gtaaattgag cctgcatatc tgttggaaat cctgggtggg gcaaggtttt cacatgaaca
    23041 gcttttagat tttccagttg agaacgaaca cgaattcctt cgtcttcttc aattacttca
    23101 acacccattt caagtaactt ggcaatcaag ggacggttgt gctcccagac agcgtctcga
    23161 atcaagacat caccaccagt catggcagca gctaccataa aggttcctgc ttcgatacgg
    23221 tcctggacta cattgtgagt cgtaccatga agtttctcaa caccagtaat ggttatagtc
    23281 tctgtaccag cacctttgac cttggctccc atttcattaa ggagaatggc taagtcaaca
    23341 atctcaggct cacgcgcagc attctcaatc actgtcaccc catcagccag agtcgctgcc
    23401 atcatcaagt tctgcgttgc accaacactt ggaaagtcca tatagatatg agcaccatgc
    23461 aagcgttctg cctttgcttc gatgtaacca gctgtctgac taatcttaac ccccatagct
    23521 tccagacctt tcaaatgaag atcaatagga cggctaccaa tcgtacaacc acctggcatg
    23581 gataccttgg catgacccac acgggcaagg attggcccta atacaacgat ggaggcgcgc
    23641 atcttactga catacttgta aggggcttcc tcagtgatgt cgccagtagc atccaccttg
    23701 acaagatgag cttcctcatc aaagtcaacc ttggcattca aaccaccaac tacctgattc
    23761 ataataaaga catccgacaa aatcggaaca ttctgcaaga cggtctttcc ttcacttgct
    23821 agaatagtcg ctgccaacaa gggtaagact gcattttttg ctccctcgat cgtcacgctt
    23881 cctaccagac gattatcgcc accttgaacc acaattttat ccatactcgt ttcctttact
    23941 cttgatttta taataatcct ctaagcgctt cttgccacaa atgatacagg ctaataaaga
    24001 aagaactcag gatgtagcct atgacaatgc taaaaaaggc tactaataca cgaacttttc
    24061 ttgtattctc agctgtcact tttaaaacct tttcccatct aacaagatcc tttaaaaggt
    24121 aaaaactcac ataaataaag agcatatgac tacttagagt gaataataat tgaaccattt
    24181 gactattata ccatcttctc tgtttgtgcg ctagtttgga aacttcactc aaaaattagg
    24241 gattgttttt caagtaatca atcgcatctt gtagggtttt aacgggcacg attttcatat
    24301 ccgtcttgat tgttttagcc gcttctaggg ctgtttggta gttgtttttc gcgtccggat
    24361 gcgccttttg ttcttcttcg ctaacagggt tatcaggagc aaagaaaata gcagcacctg
    24421 ccctagccga agctacaacc ttcttatcaa tacctccaat gtctcccaca ttaccatcgc
    24481 ggtcaatggt acctgtaccg gcaacaatac gaccattacg aagatctggg tgagctattt
    24541 gagtatagat agctagacta aacatgagac cagcacttgg gccgccaata ccagctgttg
    24601 aaaagctaat tgggacattg ctgattacct ctgtacgatc aatcaagccg attccaatcc
    24661 cattttttcc attttccaag gtgataatct tcccttctgc agacttggtt tgcccatcct
    24721 cttcataggt gaccttgacg gaatccccta atttttgaga actgacgtaa tcaatcaagt
    24781 ctttggaact atcaaaggtc tgatcattga ctgctgtgac tgtatcagag atattgagaa
    24841 tccctttaaa ggttgaatta tccgtcacat tcaaaacata aactccaaag tacttgagtt
    24901 cgatatcctt accagctgtt tttagtcctt gatacttggc catattttgc gatgtttgca
    24961 tgtagaattg attgattcgc ataaattcaa catcggaaga accacctgta gtctcctgag
    25021 cactacgaat atctgtaaaa ggtgtcaacc aagcataaat catatgagct aaagtagcat
    25081 gttgaacacc aaccgtaacg aattgatagg caccagcttc cttatcttct gtgtcattta
    25141 ctttaaggac ttggcgaata tcttccgaac cacctggaac ctctatataa taaggcaagg
    25201 gcactacaaa tgccaagaaa gtcacaatca aggccgcaat gacgtataag ggccatctaa
    25261 tctttttttt catttcttat ttcctccaaa atactctcgg gaacatagca ggcaatatcc
    25321 tgaccaaact tcaaaagctc tctaacgcct gatgaactga tatagagatg ttcaggtcga
    25381 ctatgtaaat aaatagtctc tatatcagaa gacagctgat gattgtagta atcaaaactg
    25441 gcttcatatt gcaaatccga cgcattcctc aaaccacgca ctagacaagt agcacccaat
    25501 ctttttgcaa catcgaccac caattcatca tgagaagcca cgacttcaac attttccaaa
    25561 tgtcccaaag ccttttctag cccccgttta cgattttcaa gagggagaaa tccttgtttg
    25621 tggggattaa aaaaaatacc cacacaaagc ttatcaaaaa gtctgctcgc ccgttcaatg
    25681 atatccagat gcccatttgt catcggatca aatgagcctg tgaataagcc aatcttatct
    25741 gacatagact gtcaccttac taattccata aatcttttcc ttccagatac ccagacaggc
    25801 aatttcttct ggaagttcaa cggtcttatc cgtctcgcac acaaccataa catcttcaga
    25861 aaaaagctct ctctcagcca ttttttcaat atctgctacg atttgttcct tggcataggg
    25921 agggtctaag aaaacgaggt caaattcccc agatacctgt tccaatgccc tttctgcatc
    25981 cattttgagg agttgaaatt ttccaacttc cttggtcatc tggatatttt cagccacgat
    26041 ggtctgagcc ttacggtctc gctccaccaa aacagcactg gacatgccac gcgatactgc
    26101 ttcgatagat aaaccaccac tacctgcata aaggtccaag actcgtccca cttcaaagta
    26161 gggaccaatc atgttaaaaa tggctcccct aaccttatcc gaagtaggtc ttgttgtctt
    26221 gccttctagt gtcttgaggg gacgtccccc atagattcct gatacgattt tcatactgtt
    26281 tattatacca aattatagac aaaaagagaa agaaaaccga accttgcggt tcgattctct
    26341 acaaaatatt ttcgtaagta tcgcggactt cttgaggcca aacacttgtt tgcacttctc
    26401 cgatgtgtct cttgcgaagt aggaacatgg ccatacgaga ttgtccaatt cctccaccga
    26461 ttgtcaatgg gaataggcca ttcaacaaag acttgtgcca ttccaattct aagcggtctt
    26521 catcacctgt aatttccacc tgacgtctaa gagtttcttc atctacacga attcccatag
    26581 aagacaactc aaaggctcca cctaaagact cattccagac aagaatatca ccatttagac
    26641 ccttgtagcc attctcagac tcgcttgtcc agtcatcata gtctggtgca cgtccatcgt
    26701 gcggtttacc atctggcaac tcgccaccga taccaatcaa aaagacggct ccaaattctt
    26761 tacaaatcgc attttcacgt tctttaggtg tcaagtctgg gtagcgttct accaattctt
    26821 ctgtatggat aaaggtgatt tgttttggca agatagactc gatgtcatag cgggcttcaa
    26881 cagctagctc agtcaggcga atagccttat aaatcttctc aactgtttct tttagataaa
    26941 cgatgttacg cttaccattt gggataacct tctcccagtc ccactggtca acataaacag
    27001 agtgggttgc atccaaggaa tcctcatctg gacgaagggc tttcatgtgg acaaagagac
    27061 cctctccttc accaaagcca aaacgagcca aggtgtggcg tttccattta gcaagtgagt
    27121 gcaccacttc ataagtagca tcagggattt ggagaacctt gaccgatact ggattttcca
    27181 caccagacag gttgtcctgc attccgtcac cgaccttact caagatagga ccttgaactt
    27241 cgacaacttc tagcttatct ttcaaatact gggtaaaagt gtttttgaca aaggaaattt
    27301 cttcttgttg atggataaaa cttttcttca tagacaactc ctcaaaaatt taataaacgt
    27361 attatacacc tatttccaag aaaagaaaag agaaaatttt aaaaaaatca gtgtcactca
    27421 aaacactgat ttcatagacc ttttagtcat tgcgaccaaa gatacgtaga atacttagga
    27481 aaagattgat aaaatcaaga tagatgctga gagccattga caccacccag cctgtcgcta
    27541 cacgaccttg tgattgttca taggcgaggc gaatcttttg gttatcccaa gcaatcaacc
    27601 ctgaaaaaac caaaaccatg gctacgctaa tcatataatc aaagaagcca ctagccaaga
    27661 aaatattgac taccatagca atcagtaaac caatgagagc tgccatcatt gctcgaccaa
    27721 tcccactcaa gtctttcttg gtaaaaatac caactgccgc catgacaaag aagagaaggg
    27781 cgctcgatac aaaggcagat aaaactgtac ccggagtata gaaagccacc acaaaactaa
    27841 gggtaaagcc gtttaaaacg gagtaaagta aaaatactgg aagagcagct ggactatttc
    27901 ttgaagccat gctactggca acgaaaacca aagccaactc cgcaaaagta gcaatggtca
    27961 accagagacg cccctgcatc aacaagtaaa ccaactgaga ctgaaagacc gtcaacataa
    28021 ggcctgatac caaagcagat agtccgattc ccagaccaac aaaggcataa accttagcgt
    28081 aaaattgatt gagacctgca cggtcatgta taatagtgtg attcatcctt ttctcctttt
    28141 ctgtgaacat ctttccttga ttataacaaa aaaagttaaa attagcttaa atggaagatt
    28201 aaaataccgg ctgcaactgc aacattcaaa ctctcggcct gccccttcat gctaatatgg
    28261 accaactggt ctgcactttc agccataagg ggactaattc cttgaccctc atttcccata
    28321 actagtacaa aattttctat agaaggcagt tctctgtaat caacagaatc tttagatagg
    28381 gttgttgcta gcactgggat agctaccttt ttagtttcgt caagaagcgc ttgactagtc
    28441 atccggtaaa tgggcagatg gaaatgacta ccttgcatgg aacgtagggt tttgagactg
    28501 tagatgtctg ccgacttatc tgaaacaatc actcctgtaa aacctgctgc atccgcagtt
    28561 cgaatgatag ttcctacatt accaggatct tgcacatctt ccaaaaacaa gaacttgccc
    28621 tgactcaaat cagcttgtcc tacttcttct ttttgaacca cggcaacaat tccctgtgga
    28681 gtctgagaat ccgccaaatc tagcaaaata tcctctgaaa tccagacagt ttgcggaaaa
    28741 gcagctaact gatttcgata attttctagg gcaaagattt tctcaatcgt cactccagct
    28801 tggacagctt cttcaaacaa gtgccagcct tcaatcaaat aggcagactt gcggtatttt
    28861 ttttggtgta atttcttggc attttttacc acagaattgg cttttgaggt tataatagtc
    28921 atagaaatat tataacacaa tcaaaggggt ttggtatgca aaaggttaga atgattgccc
    28981 aaggtagggt gcagggagtc ggctttcgtt ggggtgttta tagcctggcc cttgaaatcg
    29041 gtggcatcac aggtcgggta tggaataacg acgatggcac agtggaaatc ttagcccaag
    29101 cagactcatc tgctatcatg gcaaaattta tccaagaaat ccgaaaagga ccgacacctt
    29161 tttcaaaagt aagctactta gatgtcaaac taagcaactt tcctccctac tctgacttta
    29221 aaatcgcaaa ttaggtctcc agaactattg tatattttgt aaaaaaacag tagaatagaa
    29281 aggtataatt tttaaagaag gaataaaaac agtgaaatct attaaacgtt ttgcattctc
    29341 ggctatggga gtggctatgt tgcttgtctt gactggctgt gtcaatgtcg ataaaaccac
    29401 aggtcagcca acaggattta tttggaatac gatcggagcg cctatggctg aagccatcaa
    29461 gtacttcgct actgataaag gtctaggctt tggtgtcgct atcattatcg taaccattat
    29521 cgtacgcttg attatcttac cacttggtat ctaccaatca tggaaggcaa cgcttcactc
    29581 tgaaaagatg aacgctctca agcatgtcct tgagccacac caaacacgtc tcaaagaagc
    29641 aactactcaa gaagaaaaac tcgaagccca acaagccctc tttgccgctc aaaaagagca
    29701 cggcatcagc atgtttggtg gtgtaggatg tttccctatc ctccttcaaa tgcctttctt
    29761 ctctgctatc tactttgctg cccaacatac tgaaggggtt gctcaagcaa gctacctagg
    29821 cattcctcta ggttctccaa gtatgatttt ggttgcctgt gctggtgtcc tttactatct
    29881 tcaatcgctc ctttcacttc acggagtaga agatgaaatg caaagagaac aaatcaagaa
    29941 aatgatttac atgagcccac tcatgatcgt cgtcttctcc ctcttctcac cagctagtgt
    30001 cacactttac tgggttgtcg gtggtttcat gatgattctc caacagttta tcgtcaacta
    30061 tatcgttcgt ccaaaacttc gcaaaaaagt ccgtgaagaa ctagccaaga acccaccaaa
    30121 agcaagtgct ttctctaaac caagtggacg aaaagacgtt acccctgaac aaccaactgc
    30181 tatcacaagc aagaaaaaac acaaaaatcg caacgctgga aaacaacgtt cgagataaga
    30241 agaaaaaggc ttagctgatt tgctaagtct ttttgcaaat caaaagcccg atgtttccat
    30301 caggcttctt ttctatccat gtacacgttt catataatct tgataacttt cggtatccat
    30361 gagtttttta gcgttcttga cgcgatctgc tgttggtggt ttgactcctt cgagggaata
    30421 tggaattcca agttcacgcc acttgaactc acccatggtg tgataaggta gaatttcaaa
    30481 cttatcaaca tttttgaggg tcttgacgaa cttaccaagt tcaatcaagt catcatctct
    30541 gtctgtcaat cctggaacta gcacgtggcg aatccagaca ggttttccaa tatctgatag
    30601 atactgggca caagccaaga tatttttatt agtttggcta gtgacaatct tgtgctgttc
    30661 ttcgttgatt tccttgatat ccaaaagaac caagtcagtg acagccatga gtttgtcaaa
    30721 cttctcaagg taacgtggtt tattacggaa aggaagagca caggtatcca aggtacagtg
    30781 gattccttgt tccttagcct tggtgaagag agcaatcagg aaatcaatct gcaagagagc
    30841 ttctcctcca ctgactgtaa tcccaccctt atttccccag aaaccacggt agcgcaaggc
    30901 ctctgtcaag acatcatcta ccgtccgttc acgtgactta ttggactcca tagcccaagt
    30961 gtctgggttg tggcaatact ggcaacgcat gtgacagccc tgcaaaaaga caataaagcg
    31021 aataccaggc ccatctactg acccaaagct ttctgtcgaa tgcaccattc ctgtcacttg
    31081 tccataatca attgtttctt cagacatatc gttaccttcc ttgaaaacgt tttatagttt
    31141 tattatatca cgacttgaag gaaaaacaag atttttgcct attttttaga aagcaatctg
    31201 tttttcaatt tcattttcaa tctattatca gattattctt caaaatcgaa gccatataag
    31261 gttgcaaaat agtcctcagg gcgctctgca cggcggattt gacgggcttt accttcttcg
    31321 gtatagagga tttccgcaga acgtaatttg gcattatact ggtagcccat tgaaaatccg
    31381 tgggcacctg tatcatgaat taccagcaaa tcaccgattt ctgtatgagg cagttcgcga
    31441 ttgactgcaa atttatcatt gttttcacag agtgaaccaa ccacatctac cgcttcagct
    31501 ggtccatctg gatgggtcac gttgctaata tgatggtaag ctccgtacat agctggacgc
    31561 atgaggttga ctgctgaggc atccacacct agataggtac ggtaggtttc cttcttatga
    31621 gtcactcttg tgactagagc accgtgaggt gccagcataa aacgacccaa ttcggtgaaa
    31681 atcttgacct gaccaagacc tgctgacgta agaacttctt catacacctt acgaactccc
    31741 tcaccaatca aggcgatatc gttcggctcc tggtctggac gataattaac accaataccg
    31801 ccagaaagat tgataaagtc tagcgaaatg cccaactttt ccttgatttc aacagccagt
    31861 tcaaagagct gacgagccaa ctctggataa tagagatggg tcacggtatt ggacgctagg
    31921 aaggagtgaa tcccaaaagt cttggctcct ttttccttca agatagcaaa ggcttcaaag
    31981 agctggtcct tggtcatgcc aaacttagcc tccccaggat tgtccataat gtctgtcccc
    32041 agttcaaaaa cgcctccagg attataacga caagagatga tttctggaat gcctgctact
    32101 ctctccagat gttcaatatc ttcaaaggca tccaagttaa tggtcgcacc caattcacgt
    32161 gcataggcgt attccttgtc tggcgtgttg ttggaagaga acataatctc agaacccaga
    32221 aagtccagtt tatggctcat caaaagctct acataactag agcagtccac accacaacct
    32281 tcttcttgga gaattttcaa aatagctgga gttggagtag ccttaactgc aaaatattcc
    32341 ttaaagccct tgttccacga aaaagcttgg ttgacggctc ttgccttctc acgaatcccc
    32401 ttctcatcat acaagtgaaa gggagtcggg aactcggcaa caatcgcttc taactcttct
    32461 ctattgataa atggtgtttt cataagcttc cttctattct gtttgcaaag aaaggctggg
    32521 acaatcgttc caacctttag ttctatctct tatttatctt cgtcaaagat attgccaacc
    32581 tcaacatcga tggcttggtt cttgacatca atattggtta ccttcaagag tgacttgtag
    32641 tcaaactgct tttcacgttc ttcttgggca ttgtccgcaa agaccgctac acctgccagt
    32701 tctgagtcga actcgtgcaa gagactaatc ataccattga ccgttccgcc acctttcaag
    32761 aagtcatcca caatcaagac acggctgcct gccttaagac tacgttttga aaggaacatt
    32821 ttctcgatac ggtcaccact tgaacctgaa acatagttga cgctaacagt tgaaccttcg
    32881 gtaattttca ggtcacggcg cacaatgaca aaagagacat tgaggacatt ggcaactgca
    32941 tttgcaagtg gcacaccctt agttgctacg gtcataaccg cgtcaatttt ttggtccata
    33001 aagcttttgg caataatacg accaatattt ttcaagatgg ctggtgtgct aagcaaatca
    33061 gacagataga tataaccacc tggcaagata cggtcacttt ctgacaactt ggtacgcaag
    33121 tcttcaacca tttccttagc atcctgactc gaaatagacg gtgtgaagat gacacctccg
    33181 ccagccccag tcactgtctg gatatgaccg atttcaattt cctcaaaggc gcgtttgata
    33241 atgacgatat cttctgagat ggatgattta gcagactcat acttttcagc aaaagtattg
    33301 agactagtta gtttataagg attattaatc aaatagttgg aaatgacaac catccgatca
    33361 cttcttctta atttcatttc tatttcctat tccattttta ttcaaaaaat caaaaagcaa
    33421 actagaaagc tggtcgctgg tggttcaaaa cactgttttg agattgtcaa tagaactgac
    33481 aaaccctgta atatacctgc atatatacat acgacaaggc gatactaccc tagtttgaag
    33541 agattttcga agagtattca tttttgtctt ttacttatta taccatattc acataaaaaa
    33601 acgaacattc ttatcctaaa aaatgctcat ttttcttaaa ttatcaatct aaatctggtt
    33661 tatagaagga acgattatcc atagcgaaga ttttattggt catctctcct ttatccacca
    33721 aagccagagc tgttgacatc atcatcatgc ttgcatccag attgtcaatc atatggataa
    33781 tctctgcctc cataatacgt ggacggactg gacttccata ttcaagcaag ccgtggtgac
    33841 tgaggatgac atgacgaagc aaaacgactt cttccttggt atcatcgatg ccgagttcca
    33901 taactgtctt ggtaatttcg ctatcaatga gagcgatatg tccaagaaga ttacctcgca
    33961 ctgtgtactc tgtctggtct ggccccgtca actcgataac cttagctaag tcatgcagca
    34021 taatccccgc atagagcagg ctcttattga gctgaggata aacttcgcta atagcgtctg
    34081 ccaaacgtac catggtcgcc gtatgataag ccaaccccgt ttcaaaggca tggtggttgg
    34141 tcttggcagc tggataggag tagaattcct tatcatactt ggtgtagaga tttcggacaa
    34201 tccgttgcca gacaggattt tcaattttga aaatcatttg cgacatgtag tcacgaattt
    34261 ccttgacatc aactggtgac ttgaccttga aatcggctgg gtcattgggt tcaccagctt
    34321 gaggcaggcg gagagtaatt tgattgactt gaggggtatt gttataaact tctcggcgtc
    34381 ctttcatgtg gacaacctta cctgcggtaa aggcctcaat gttatgaggt tgggcatccc
    34441 agagcttccc atcaatctcg ccactatcat cttggaaggt aaaggctagg tagtttttcc
    34501 cagctcgagt ttgcctcagg tcagctgatt tgattaggta aaagccttca aatagctcat
    34561 cttttttcat gtgactaatc ttcatattct tcctcatttt cttgaaaatg gagtagatca
    34621 agcgcaggct caccttctga caactcaatg tgacggagcg tccgctcgat agctatggta
    34681 cgacggttta ataattcatc aatattgcca gaggcatgtt ggagatgttt ttgtgccttg
    34741 accagaatac caccaaactt gccaaactcg gtcttgacac tggcaagagt cttgctgata
    34801 tggtcggcac tcttttggat attaagggtc ttgaaaccaa ctgatagaga gttaagaagg
    34861 gctgataggg tacttggtcc tgcaacaata atctgttctt cccgtctcaa atcatcaaag
    34921 aagaccggat tgcgcacaat ctctgaataa agaccttctg tcggaacaaa caagattcca
    34981 aagttggttg tccgaggtgg tgctatgtac ttgttcctaa tatccctagc aaagcgcttg
    35041 acgcttgcta ggagtgactt acgacagcgt tcaatctcat ccttgtcacc tgtctcatag
    35101 gcttcttcca agcggtaata atctgccagt ggaaacttag agtcaattgg cagatagacg
    35161 tattcttggt cgccttgtcc gggtaacttg atggcatact ccactcgttc actagagttt
    35221 tcaaccgttg cgtattctcg ttcgtactgg gcaggtgtca tgatgtcttc aataatttgc
    35281 cccagttgca attctcccag aatccctcgc gtcttggttc cagagagaac cttgttaaga
    35341 gctccgacat cacgggcaac tgtctgcatt tctccaaggc cacgattgac agactccagt
    35401 tgtttagaaa ctgtctcaaa ggaagcctgt aagcgtgtct gcaaggtctt ttctagtttt
    35461 tcctcgaccg tctggcgcat ttgttccaaa cgttgctcat ttgattcctg caaggcttgg
    35521 agacgttggt ctgtcttgtc tctagtttgg aggagattat ctgtcatttc ttgacggact
    35581 tgggtcagac cttggtgcaa ttcaatccgc acttcttgca aacggtcgct gacaaccact
    35641 tccaaatctt tttggtctaa ctggctggct tgtctggctt ggtcaaagcg gtaatccaac
    35701 tggtctgaca aatgatctgc ctgatcctcc aagctcttac ttaagtgttt ctcctgccta
    35761 tcctgccttt gccaaatcag aaagagacca gctagattgg caattaataa tagaataagt
    35821 aaactttcca tcctacctcc tgtccttgct atgcagtacg accacataac catctgggca
    35881 agttaccgac acttccctat ctatatattc gttagaagcg tacacttttt taaagaaaaa
    35941 attttcctct gtcaactcat acttggctcc aagaatagtc agctggctat cccgaactgg
    36001 cataaaggct agatagtcgt agtctgaacg aggttctagc tgactgattc cttctggaca
    36061 ataagtaatc aagttttgcc catcctcaat ttctatttga tgcatatagg atgccaactt
    36121 aggattgcta ggcagaaaga cattggccaa catatggtca atacggccac ccaaggcacc
    36181 gaaaatagta acctgagcct gaggattttg cttaaagatg gtcaagagag ccaattccaa
    36241 atcagtatca tctttttctg gccgggcttg gacaaaatac tgggcacgtt tttgaatcac
    36301 ctgtcgctct tcttccgtca cagaatcaaa atctccgact gctagagcaa gaggcaaatc
    36361 ttcttccaag atccagagcg agcctcgatc cacaccaaca aaaccatcaa agtccgtccg
    36421 ataatgaccg cggtctccgc ctgcaaaaac ggcaacccta gtccagttgt tttctgagag
    36481 tttgtactcg ctcattgaca tctcccttaa agacatagga acctgctaca aaaacggtcg
    36541 caccagcttc tttggcttga gcaatagttt ggtcatcaat cccaccatcc acttcaatct
    36601 caaagttcaa acctttttca tcacgaaggg caaccagctc acgaacctta tccatggttt
    36661 ctggcagaaa ggcttgacca ccaaatccag ggttaactgt catgactagg acttggtcaa
    36721 ctagatgaag cacatgctta atcgcttcaa ctggtgtacc aggattgata acaactgatg
    36781 gcttgacacc gagtgaacga atcttttgga gggcaccatg aatatgaggc gttgcttcca
    36841 catggatact aataatatcc gcacctgcac gcacaaagtc ctctaaatga tgctcagggt
    36901 ttgacaccat caagtggcag tcgaaaacca tcttactatg aggacgaaga gcttcgacca
    36961 cacccgcacc aaaactgatt tgcggcacaa aatgaccatc cataatatcg atatgggcat
    37021 actctgcccc agttgcttct aggcgtttaa tttcacgttc aaagttggca taatctgctg
    37081 ccagaattga cggagcaatc ttgtattgag acataggttt ctccttattt tggaattttt
    37141 ttgctgactt ttttataggt ttctctgcga ttttcaattt cgctgaggaa ttgcaggtag
    37201 ttgtcaaaac ggaagggcgc aatggtacct tcttcaactg ctggcttgac agcacaggac
    37261 ggctcatggg tatgggtaca agtacggaat ttgcagtctc gactgacagt ggcaatctct
    37321 ggaaaggcct gattgaggtc ttcagccgtt gatacttcat aatccagtga tgaaaagcct
    37381 ggtgtgtctg cgattttacc cccattgagg ttgtaaaaac taacagctcg agtggtatga
    37441 cgcccgcgac ccagactgtc tgaaatttct cccgtttcaa gattaagatc tggtgcgatt
    37501 ttattgagaa gagttgattt cccaacaccc gtctgcccca taaagaccgt aaccttgcct
    37561 gttaacaaag gcaggagttc ctctttactg gtcacaaagt catatccgat gtcaccatag
    37621 gtctgctggt aaaaatccag ttctcccccg tcttccaaca aatccatttt agaaatatag
    37681 acgatgggat gaataccctt atgctccaaa agaaccaaga aacgatccag caaattgctg
    37741 ttaaaatcag gttccttgac agacatgatt actacagctt ggtcgatatt gacaataggc
    37801 ggacggacca gactgttttt ccgttcgtga atcttgagaa tatagccttc tgaattttcc
    37861 tcggcagaga aatctaccca gtccccaacg taaggggtat gccctttttt acggaaattc
    37921 ccacgcgcgc gtgtttgata gacttggcca tcactctcta catagtagaa cccagccaag
    37981 gctttaatga tttgtccctg caaaataact cctttaaaat tgttagttcc attataacaa
    38041 aaaaaagcta ttttagctta gcttctcttt acaatttcga taagtctatt ctaaaagaaa
    38101 aagatacact cacgctttag ataccaagtt ttatacaaaa ataacgaatc tacctcctta
    38161 tataaaaaca ggcgaacaga gagcctaaaa ctccctgttc gctttacttt ttctgtgtgt
    38221 aatagaaaaa acctaataaa gcaagacaaa aaatatgaat ataaactcca tacatcatgt
    38281 ggggaaagac agactctata aaatagcctg gtagatagat gattggaaat tgatagaaat
    38341 cataggtcgt tagagatagt aaacaaagaa catacataaa tactgctaca attagaaccc
    38401 atccttgctt tcgccataga aaaatcatca ataagaacag acaaagtaga tagattgacc
    38461 aatttcgcaa cataaattga aaaccataaa tcatactttc agtcgtttct ccatcaatca
    38521 catcaactac tttatagaaa ggtaaacaat agctcactaa aaaaagaagg ggactaatta
    38581 tttttttcat attctctacc atggattatt ttgcaagtaa gctgaccatc tatctccata
    38641 tcgaatcaaa ttaacagtat aattagttac tacccgattt tcacctggtc caaccttaga
    38701 aaaacctgtg ctatactccc aactacttct tgcacctgga tgaaaccatt tttgctggga
    38761 tgaataccaa ccaccttgtc taacttccac acttgaagat tctatttcga tatccctttc
    38821 atggaagtca actcctccac ttattttagt aatatttttt tgtacacctc catcataact
    38881 cacccagtga acaacagtat acaattccac actataagta ctatcaaact gactttgatg
    38941 agtagtaatg ttttgagtat aagcgtgcac tttctgtata ccaaaaatat ggtctaatat
    39001 attcgttggt ttagcaagct tattgtaacc ctcttcaaca aaagtagcct tctctaaatc
    39061 agcggtataa acagtttttc cttgtactac ttgattgttt atagaagtaa tacggctatc
    39121 cacaacaatg ggggccacca tatctccatc gctagtttct attttagctg cctctttcac
    39181 ctcatataca actcgatttt cttcagactg aatcacttct accccatttt tttcaggtat
    39241 agataatcta gtttgcccat tagaaaccgt tatatttgga ccaatattct tctcatttgc
    39301 ataagtcgca ataggaaatc ctgatagaac cactgcacac ataaggctat tgactaattt
    39361 ttttctcatg aatatatcct tcccattttc aagaggagta aaaatagcta atataagatg
    39421 aacgtttcct tatatttcag aataggatat ctatctgaaa gcaattcaca ctcctataga
    39481 taactgttcc aaatcttggc tacatatatt tcaatagttt gctacaaaaa actcctttct
    39541 aagtctattg aacatgccct tattcaccta ctaatatatc acaaaaataa ataaatacaa
    39601 gactgttttt tctactagtt ttatgataga atagtattgt tagggtaaat ttcatatata
    39661 aatgtcgagt gaaaaatcga tggagcagaa atcggtagac aaagactcga tttcgttggt
    39721 ccagccccac aaggctaatc aggtatttca cgagtttaaa aatctaatga agtgcccaat
    39781 caactactga ttcattgatt taatacgaac tatagtggat tgaacctaga aatagtacac
    39841 taaggattct aaaacgtttc tagaaattaa tttgactttc ctaatctctt tgttcatatc
    39901 ttatttcaat ctactatata taccaaaatg ctaggacaaa agtctttaaa atcagagaaa
    39961 cgcatattat caggtgttgg aaaaccttga taatatgcgt tttatcatag aaagatctac
    40021 ttcatttttt actaaaatta agtttttgtc cctgcatctt agagtccttg ccctttaagt
    40081 gcatctgcta ggctggcaaa ctcttccaag ctgagagctt ccccacgcac acttggtgac
    40141 aagcctgctt ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttgccaaag
    40201 taacctgtca agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc
    40261 ttaaagaaaa agttctcgtc ttccactgct acagctggca ctggacggcg caccattttc
    40321 aagatggctg agtctacatt tggtgctggc acaaagactg tacgcggcac gataaaggca
    40381 accttggctg tcatgtaata ctgcacagcg atagacaagc taccgtaagc cttggtattt
    40441 ggttgagccg agatacggtc cgccacttct ttttgcatca tgaccacaaa ctcactaaaa
    40501 ggaatgccac tctcgattaa gtgcatgaga ataggcgttg tgatgtagta aggcaaatta
    40561 gccactacct tgattggcag gtcaggattt ttgaaattct ggatatgttg cgccaaatcg
    40621 accttgagaa tgtcctcgtt gactacagtc acattgtcaa aatcacgcaa ggtatctgcc
    40681 aaaatcggta ccaaacgatg gtcgatctca aaggccataa cttctgctgc acgctcagcc
    40741 aaaaactcgg tcaaggcacc aatacctggc ccgatttcaa tgacattgac ctggtcatca
    40801 atctcagccg tatccacgat tttttgtagg atattggtat ccgtcaagaa attttgccca
    40861 aaggactttt taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct
    40921 gcaattctca tctattctct tttctattat ctgttactac tattgtaaca cattcccctt
    40981 gtattttggg ggtgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct
    41041 tggaaatctt taaaagtggc cttagcgctt ctctcgaaac atacgttcat actcttcgaa
    41101 aatctcttca aaccacgtca gcttcacctt gccgtactca agtacagcct gcggctagct
    41161 tcctagtttg ctctttgatt ttcattgagt atcaaaaaaa tcagcttctt gataacttcg
    41221 attttcgggt agggtcaaat ccacatcctc ctccacatca tccactgtca gttcaaccgt
    41281 ttgaggtaaa tttttcaaac gataatgctt ttgcctttgc ccttcactac tagcaaaatc
    41341 aagcaaatag ccatgcactc ggatttgaac caaaaggaga ggattggtca tattttccat
    41401 gatgaggata tcttataaac cacctctggc actaggataa tcagataccc tgcgaatacg
    41461 gattttttca cacatgagca agtttcctca tatcaatgat ttcatcagcc ttattccaga
    41521 ctaggggatt atgggtcgca atgatgataa ttcgattttc atctttcaaa tccaccaaga
    41581 gattcataac ctcctctgaa ttttcaggat caagagctgc tgttggttca tctgccaaaa
    41641 tcaagggtgg atttttcaaa atagttttcg caagggcaac tcgttgggcc tctcccccag
    41701 ataaagtata aattttttgt tctaaatcca aataccctag attaactttt tctaaagccc
    41761 ccacttgcct ttccaaacgt tctacttttg agattttctg accaacaaaa cccaaatcca
    41821 aattttcttt gattgattgg ttttctaaga ggccaaaatt ttgaaagaga tagcccatct
    41881 gatctcgaaa atactcacga gtgggaatgg tttttaaatc tttcccctga tagagaaccc
    41941 ttcctccatc tatcttttct agctttccca agatattcag cagcgtcgtc tttccgcttc
    42001 cactctttcc gattaaggca taaaccttgc ccttctccag cttgagattc aaaccagaga
    42061 aaatcgcgcg gtcattaaat ttcttttcca atccttgaat atcaatcatc ttattttcct
    42121 ttcaatactg ccatgctacc agcttcttct tttttgtcct gccttactaa aatcaagagg
    42181 gcgttaagcg taaacaaagc tacaactaga gcgctaatca aaccatctct tgtcaaaata
    42241 ctagatagga ctaggccaag caagagaact cctccttgcg ccagtaaata cttgccatga
    42301 agctcataga ttgtcatacc agcaagacgt ttaatcataa gctcccgtct gaactgctca
    42361 aaatagagaa gattcatgga atcaaataac aagatagccg tagacagggt caaaatcgtc
    42421 ccaataagga gagagtaaaa ctctacccgt ttgtcattta gtaccttggc aaaaaatagc
    42481 tggcttttta ccaagtaaga aaccttgtga tacagacctt gctcttttag agctgtgatg
    42541 ctgtctccat atcgatctag tttcaaggca ctattagccg tagttcccca caacatccct
    42601 gcaacaggtc ttgttccagt cgcttgcggc gttagaacta caataatcgg atcttttagg
    42661 tactggcgtg ttgtcttgta cccatcatta tagaggaaac gttcctgtcc tgtttctgta
    42721 aaagctagac ttacctgtgg gaggtagtat ttctgactca tcacttctac actttcagat
    42781 gaaaagtttt gcaggtaatc tgtaaacaat ctttggtagt aggtagactg ctctcgcaag
    42841 ctctcaggca agattagccc aaactctccc tcagacaagt tttgcatctt gtccataaac
    42901 tctgaagaaa cggtaatctt ttcttctatc agatagcgtg gtgagacata gataacattc
    42961 cctgacggtg tgtagtcact gagacgattg ccatctaggt ccacttctgc tccgtctgag
    43021 aaattgtcaa cattgctcat aatataaaaa gagtctgtat tggctaaccg ttcttcagta
    43081 aatgtctgcc actcacgatt atccttacgc gttccttctt catcggcaaa tgcactagac
    43141 caaccaaagg atagacggta acggtctgag gactggctcc atttattgct agctctctcc
    43201 atttcctgca tttcacggta gtggggtagg agagctgtcg cactcgatcc gaccaccaat
    43261 acagctaaga gttgccccac catcatcaat gtcatcatac gtttgagagg gagtttccct
    43321 ttcaatagat ccaccagact attttcctgt aaaccaagta gatagacgac acttagtaag
    43381 gtagaaatcc ctgccagggt caatccataa agtagaagag caatgatgac cagttgcacc
    43441 gttgccataa acaaggcacc ttgataccag agaatcccca atcccaaaag actggatacc
    43501 agcactgagc agataaactg tctcacatct tctaacactg gtctgagagc aactccaaac
    43561 aagctctcac cagctattaa gcgaatccct gcctgacgaa gggatttgat ccgataaatc
    43621 agggtcagac tcataaaggt cagcagaaaa atagctaaac tcagtagcac cataggggtg
    43681 gccgccaata gtaagactat cgaaaatgga tcttctccat tcgaaacaaa gccttgatag
    43741 ccaagttctt tcaaggtggt ctgtaagctc actccatcca aacttcctga cacaatcaag
    43801 taagacccta ataaatcact cgtttctgca ctctccttgg aggaaatggt cagaccttct
    43861 ggaagctctc cctcaccata agtggcatag gtaaagagtg tttctccagc ttcatttggc
    43921 tcaacgattc gacgggcgat gagactatta tgctctaccg ccaagtgact caaaacctct
    43981 gtcacctctt cgcgactagc tactggttga tttatcatca ttcctgtcac atcaacagaa
    44041 ggatagttac caaataaaat ctcttctcga tggtcaacgg aagttatcac catataaagc
    44101 gataccaata ccattgaaat caaaataaat aaacgtttca tcatttcctc caaaaagtta
    44161 cttggtcact tagtgagaag gtgaccacag tcactgcgat gttaagaagc ttattaagtt
    44221 ctttctacta gcaacatctt caaatacatt atatccgttt tttcaagaac tatcaaggac
    44281 atcaatgtcc ttaaaatcta actatttcat attattttta gcttatatct aaaaaaacag
    44341 ttctaaagac gaactttaga actgttttga tacgaggaca aggacatttt tgtcactgat
    44401 tcactatgtt tataaatatt ttttgacatc ctcttgccat tcctctgtca atttctttac
    44461 tagaaatcca tctccaatta gcttcgcaaa tgttttagaa gactgataaa atgattcagc
    44521 taaactaaaa tctctttctt ctcttaatgc ttgcttccac aaaaacataa atacaagagg
    44581 tttcttttga taatcttgag ttttatccat aatttcttgt aaacacgata gataatcatt
    44641 aaaacaatca gttactccta ccttttcaag acaacacatt cctgaaataa gagtatctct
    44701 aattataaag aagttttcta atttagttac ctttttctgt tccaaaagaa agagcattag
    44761 cttttcgatt tgatttataa atttggcaag atcttttcta atgagcattt gataaaaaaa
    44821 caaacgaatc aacaacatat catttgttga ataaacttct ttttctatga tctgagacat
    44881 atgttcctca agtattaact ctgcatattc aggccttcta gttctagaag tatccaaaca
    44941 cgcctgcaat acttcacatg ctaattgttc ttctttagga agattatcaa agtatgtttt
    45001 ataaatctct tccaaacacg cttccttctt atcgtactcc tcttctttac catagattgg
    45061 ttcacgtaaa atctggtatt tcaattctaa ataagcagga ggaagagctg aaaaatccgg
    45121 cataaggcta taaactggaa ctcctagccg gcgagcaata taggctaact tgggcaaact
    45181 cggttgcgaa gctccacttt caattcgcga cagttgacga actgtcagtt cttgctcatc
    45241 tccacaaaaa tatggacgac taactccttt ttctatccga atctctttaa ttttttgacc
    45301 aattaacatc agacgcctcc tcttctacct gcttcgaaaa atactgtgaa acttaaaaaa
    45361 ttgtaacggc tacatctttc ctactcataa gatttcatag cttcttccac ttctgccaaa
    45421 gtaaccccaa acaactctag gcgtttgagg agttgcttgc cgttagaata gccgattcgg
    45481 agagtctctc cgagatattc tctacgctta cggctgtctg cccctgctag aaaaccaagg
    45541 cgaatcaagt cgctacgact aatgtcaaac tgactctcat gttcaaattg ttctgtcacc
    45601 tgagctagag ccgttttcag gtcttcatag ctggcatgct caattcccag agaacgcccc
    45661 ttggtcttgg actttggaac agcttcatct cgcttgagaa aggcatgccg aactgttgga
    45721 atggccgtca taatcatgcg ccgaatccgc tccccattaa aatctgggtc tgtaaagaca
    45781 atgactccct gacgttggtg caggcgctga atccgctcta tatcctgagc attgatggca
    45841 gaacctcgag tctcataggt ctccacatcg aaataacgtt tgagattgac cgtatcatca
    45901 cgcccttcaa ccacgataac ttgagaaatt ttctctttca ttacttgctg tccaatccaa
    45961 aaatgcgttc tgcatttgca gtcgttgcta ccgccagctc ttctgtcgtc ataccacgca
    46021 agtcagcgat aaagtcgacc acatagcgag tataggctgt tttattttca cgaccacgct
    46081 tgggtacagg tgctaagtaa ggcgcatctg tttccaccaa aatcttgtcc aaaggtaact
    46141 ctttagctgc ttcttggagg tcagttacct tcttaaaagt caccactcct gagaaggaaa
    46201 tggtcatacc aagatccaca aacttctctg cccactcaag cgtccctgaa aatgaatgca
    46261 tgataccacc acgaggacca acgccctcac tcttgataat ctcataggta tcttccagcg
    46321 catcacgggt atggacaaca aaaggcaaat ccaagtcctt agatagctga atctgacggc
    46381 gaaaaacctg ctcctgcacc tctttgggcg ctgtcatcca atggtaatct aagccaattt
    46441 cacctaaagc cacaaccttg ggatgtttta acttatccaa caagtaagcc tcaacttcct
    46501 ctgtataagt accagcttct gtaggatgcc aaccaatagt cgcatagagc tgatcatact
    46561 catctaccaa ctccaaggca cgctcaatcg tcggtttatc aaaaccaaca atattcatct
    46621 gtgtcacacc catctcagca gccaaggcaa tttcttctgc ctcacgacct gcaaattctt
    46681 ctacattcaa gtgtgtatgt gtatcaaaaa tcatctcttc taacctcgtt ttctatcttc
    46741 tattatacca aaaaagagga ggggcaccta atttttcggt ttcccctcct ctcttcaata
    46801 gagagctatt ctgctatctt ttctatccga tattgcccat ctcctattcc acagttagag
    46861 acagaagaga ttggctacat tgatagaata ttcctattca gctaaagtat gtgattatct
    46921 tgggttctca cttttctcac ccatcactag gattgatgac ttctcaaaat cccccttata
    46981 atctaacttt aagtagagaa tagaattttc tagctgttct attttctacg tctagtcttt
    47041 cttcctagca aagcaaaacc acttgttgcc accactagac caagactagc aagtgctgca
    47101 cttgatgctg aacctgtgtt aggtaattgt ttgccagcag gtgactggta ggtaacatct
    47161 tgcattgttc ctgcagttgc ttgcggtgca cttgttgtct taggagcagc attaggagcc
    47221 actggtctct taggaactgt aaccatgaca atggcttgca ctccaatcgt ttctgcttcc
    47281 ttcacatctt ccatagtttt cgcattttca atctctttga gagctgcttg tttttctgct
    47341 tccactcttg ctaaaagttc tgctttttct ttatcagaaa gcggtgcgcc tttgatttca
    47401 tcctgcttgt ccttggctgc tttttcaatg gcatttttag ctgattcttt ttcagtagct
    47461 aattgcttag aagcttgtga ttgagctgag ttttgtgaac ctgtgtgagc tgatccaccc
    47521 gcctggctac caccgcctgc attcgcatta gcatctgagc ttccagtatt gcctccctta
    47581 tctccacctg gtgtattttc tagcttatac tctggtgtag cttcttgagt tacagattca
    47641 cctttcgcag attgttgaac tgtatctttt cctagaatcg tcactactga accatctggg
    47701 aatgtgattg ttgctgtacc atctccagct acattgattg tcgctccgtc taatgctgaa
    47761 ccatttgctt gtaaaatagc aaccttaact ttttcttcat ctgttaaatg agttatatct
    47821 tttacatcta ctctttgagc aggtgcttta acagttgatt tttcagcagt cggtttagtg
    47881 ctatcttgtg cttttggatc ttgtgctacc aattgatttc ctggaattgt aatagctgaa
    47941 ccatctttaa agacgattgt cgctgcgcca tctccagcta cttcaacttt atagtaaaat
    48001 gaaataataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    48061 aatagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    48121 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    48181 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    48241 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    48301 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    48361 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    48421 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agcc
//
LOCUS       DAVAZV010000009        47001 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVAZV010000009 DAVAZV010000000
VERSION     DAVAZV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47001
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.009"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..445
                     /locus_tag="VQT46_000491"
     CDS             <1..445
                     /locus_tag="VQT46_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2370578.1"
                     /translation="NRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMPMKFNTIIS
                     EMGSNISGGQRQQIALARALINNPSIVILDEATSALDTINEERITKYIQSQGCTQIII
                     AHRLSTIKDADIIFVMKGGKIVESGNHKYLITLGGEYYSLYTKRK"
     gene            458..628
                     /locus_tag="VQT46_000492"
     CDS             458..628
                     /locus_tag="VQT46_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370579.1"
                     /translation="MKKENEYVILTIASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1134..2480)
                     /gene="gdhA"
                     /locus_tag="VQT46_000493"
     CDS             complement(1134..2480)
                     /gene="gdhA"
                     /locus_tag="VQT46_000493"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET2370580.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGIFYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDGRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            2821..3555
                     /locus_tag="VQT46_000494"
                     /pseudo
     CDS             2821..3555
                     /locus_tag="VQT46_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3552..3770
                     /locus_tag="VQT46_000495"
     CDS             3552..3770
                     /locus_tag="VQT46_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370581.1"
                     /translation="MSISPRFEALEQAIASKDLEKVREAFKKMNSTWTINESVVRDNS
                     TAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(3827..4111)
                     /locus_tag="VQT46_000496"
     CDS             complement(3827..4111)
                     /locus_tag="VQT46_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET2370582.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(4165..5100)
                     /locus_tag="VQT46_000497"
     CDS             complement(4165..5100)
                     /locus_tag="VQT46_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET2370583.1"
                     /translation="MEICQQILEKIKEYNTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQKILKQYNVTDAETAAIVGAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            5204..5647
                     /locus_tag="VQT46_000498"
     CDS             5204..5647
                     /locus_tag="VQT46_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET2370584.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELAAKVG"
     gene            5763..6029
                     /locus_tag="VQT46_000499"
     CDS             5763..6029
                     /locus_tag="VQT46_000499"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET2370585.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVRSRVEDKRYQETIVATFSYILKRSRDYQDQNIK"
     gene            6026..6400
                     /gene="crcB"
                     /locus_tag="VQT46_000500"
     CDS             6026..6400
                     /gene="crcB"
                     /locus_tag="VQT46_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2370586.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIFLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYFSLV
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            6394..6723
                     /gene="crcB"
                     /locus_tag="VQT46_000501"
     CDS             6394..6723
                     /gene="crcB"
                     /locus_tag="VQT46_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET2370587.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            6842..7189
                     /gene="rplS"
                     /locus_tag="VQT46_000502"
     CDS             6842..7189
                     /gene="rplS"
                     /locus_tag="VQT46_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET2370588.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            7232..7303
                     /locus_tag="VQT46_000503"
     tRNA            7232..7303
                     /locus_tag="VQT46_000503"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7265..7267,aa:Arg,seq:cct)
     gene            complement(7470..8468)
                     /locus_tag="VQT46_000504"
     CDS             complement(7470..8468)
                     /locus_tag="VQT46_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET2370589.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(8511..9317)
                     /gene="yidA"
                     /locus_tag="VQT46_000505"
     CDS             complement(8511..9317)
                     /gene="yidA"
                     /locus_tag="VQT46_000505"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET2370590.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYERYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRPMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            complement(9330..10634)
                     /locus_tag="VQT46_000506"
     CDS             complement(9330..10634)
                     /locus_tag="VQT46_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET2370591.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTVTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPVENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKNFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLTSMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESQNPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            10706..11083
                     /locus_tag="VQT46_000507"
     CDS             10706..11083
                     /locus_tag="VQT46_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET2370592.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELMMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            11174..11506
                     /locus_tag="VQT46_000508"
     CDS             11174..11506
                     /locus_tag="VQT46_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET2370593.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDDFLQEQIEI
                     LTSIDNRE"
     gene            11518..13089
                     /gene="ffh"
                     /locus_tag="VQT46_000509"
     CDS             11518..13089
                     /gene="ffh"
                     /locus_tag="VQT46_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET2370594.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(13284..14567)
                     /locus_tag="VQT46_000510"
     CDS             complement(13284..14567)
                     /locus_tag="VQT46_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET2370595.1"
                     /translation="MKQESTVDLLLDVDQRPSAGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(14870..15583)
                     /gene="rsmG"
                     /locus_tag="VQT46_000511"
     CDS             complement(14870..15583)
                     /gene="rsmG"
                     /locus_tag="VQT46_000511"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET2370596.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            15677..16237
                     /locus_tag="VQT46_000512"
     CDS             15677..16237
                     /locus_tag="VQT46_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET2370597.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTSEEEKSVPKVDFSGLGD"
     gene            16239..17138
                     /gene="htpX"
                     /locus_tag="VQT46_000513"
     CDS             16239..17138
                     /gene="htpX"
                     /locus_tag="VQT46_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET2370598.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSSMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(17182..18741)
                     /locus_tag="VQT46_000514"
     CDS             complement(17182..18741)
                     /locus_tag="VQT46_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2370599.1"
                     /translation="MHYRHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEDLSDFTIKGDIQSDYQSLAYIPQKVPEDLKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKTAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLAQELQLTVRGQEKIGIIGPNGVGKSTLLAKLQQLLNDKREISLGFMPQDYHK
                     KLQLDLSSIAYISKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLKLVNLEDL"
     gene            complement(18980..19297)
                     /locus_tag="VQT46_000515"
     CDS             complement(18980..19297)
                     /locus_tag="VQT46_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2370600.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSPLIGLGSLKLNDQARTAWRNYDKIHYEHVKHVLSLYGPV
                     FGF"
     gene            19476..20018
                     /locus_tag="VQT46_000516"
     CDS             19476..20018
                     /locus_tag="VQT46_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET2370601.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            20018..20647
                     /gene="nth"
                     /locus_tag="VQT46_000517"
     CDS             20018..20647
                     /gene="nth"
                     /locus_tag="VQT46_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET2370602.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            20858..21379
                     /gene="pyrR"
                     /locus_tag="VQT46_000518"
     CDS             20858..21379
                     /gene="pyrR"
                     /locus_tag="VQT46_000518"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET2370603.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            21398..22321
                     /locus_tag="VQT46_000519"
     CDS             21398..22321
                     /locus_tag="VQT46_000519"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET2370604.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGAELFFAGPEEWRSQEFADYGKFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            22371..23450
                     /gene="carA"
                     /locus_tag="VQT46_000520"
     CDS             22371..23450
                     /gene="carA"
                     /locus_tag="VQT46_000520"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET2370605.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            23762..26938
                     /gene="carB"
                     /locus_tag="VQT46_000521"
     CDS             23762..26938
                     /gene="carB"
                     /locus_tag="VQT46_000521"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET2370606.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(27213..28022)
                     /locus_tag="VQT46_000522"
     CDS             complement(27213..28022)
                     /locus_tag="VQT46_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2370607.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDQFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(28024..28827)
                     /locus_tag="VQT46_000523"
     CDS             complement(28024..28827)
                     /locus_tag="VQT46_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET2370608.1"
                     /translation="MKQLTVEDAKQIELEILNYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPMDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRLVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSATFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(28837..30324)
                     /gene="tacF"
                     /locus_tag="VQT46_000524"
     CDS             complement(28837..30324)
                     /gene="tacF"
                     /locus_tag="VQT46_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET2370609.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFTDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGDILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SEASLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            30660..31367
                     /locus_tag="VQT46_000525"
     CDS             30660..31367
                     /locus_tag="VQT46_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET2370610.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDSIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            31372..32394
                     /locus_tag="VQT46_000526"
     CDS             31372..32394
                     /locus_tag="VQT46_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET2370611.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPEAEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            32411..33280
                     /gene="licA"
                     /locus_tag="VQT46_000527"
     CDS             32411..33280
                     /gene="licA"
                     /locus_tag="VQT46_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET2370612.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            33270..34148
                     /locus_tag="VQT46_000528"
     CDS             33270..34148
                     /locus_tag="VQT46_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET2370613.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            34160..34849
                     /locus_tag="VQT46_000529"
     CDS             34160..34849
                     /locus_tag="VQT46_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET2370614.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            34947..35795
                     /gene="dprA"
                     /locus_tag="VQT46_000530"
     CDS             34947..35795
                     /gene="dprA"
                     /locus_tag="VQT46_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET2370615.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            36679..37722
                     /locus_tag="VQT46_000531"
     CDS             36679..37722
                     /locus_tag="VQT46_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET2370616.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            37889..39976
                     /gene="topA"
                     /locus_tag="VQT46_000532"
     CDS             37889..39976
                     /gene="topA"
                     /locus_tag="VQT46_000532"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET2370617.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQNGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            40197..40556
                     /locus_tag="VQT46_000533"
     CDS             40197..40556
                     /locus_tag="VQT46_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET2370618.1"
                     /translation="MRIIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQAYVADFRETKSIARERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            40649..41281
                     /locus_tag="VQT46_000534"
     CDS             40649..41281
                     /locus_tag="VQT46_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET2370619.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            41325..41981
                     /locus_tag="VQT46_000535"
     CDS             41325..41981
                     /locus_tag="VQT46_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET2370620.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVYMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            42000..43094
                     /locus_tag="VQT46_000536"
     CDS             42000..43094
                     /locus_tag="VQT46_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET2370621.1"
                     /translation="MNFQLAKYSLLKRFLENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKILLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALVDKKQEITDADI
                     RALVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEFNATGQGSVEAIF
                     NAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNAAGLDFDVLKASA
                     IVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            43106..44143
                     /gene="leuB"
                     /locus_tag="VQT46_000537"
                     /pseudo
     CDS             43106..44143
                     /gene="leuB"
                     /locus_tag="VQT46_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
     gene            44140..44409
                     /locus_tag="VQT46_000538"
     CDS             44140..44409
                     /locus_tag="VQT46_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET2370622.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKSKARRRVWRIPEKILLIL
                     AFTFGGFGAWLAGIIFHHKTRKWYFKIVWFLGMVTTLVALYFIWR"
     gene            44413..44772
                     /gene="leuD"
                     /locus_tag="VQT46_000539"
     CDS             44413..44772
                     /gene="leuD"
                     /locus_tag="VQT46_000539"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET2370623.1"
                     /translation="MAGSSREYAAWALADYGFKVVIAGSFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            44934..45502
                     /locus_tag="VQT46_000540"
                     /pseudo
     CDS             44934..45502
                     /locus_tag="VQT46_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771122.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            45596..45661
                     /locus_tag="VQT46_000541"
                     /pseudo
     CDS             45596..45661
                     /locus_tag="VQT46_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            45824..>47001
                     /locus_tag="VQT46_000542"
     CDS             45824..>47001
                     /locus_tag="VQT46_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET2370624.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELMSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     "
BASE COUNT        14355 a         8375 c        10059 g        14212 t
ORIGIN      
        1 gaaccgaagt attcttgata atataacttt aaagcacgaa gttacttcac aaaagataga
       61 ggaagtttgt aaagcagttc aaatctatga tgaaatcatg gctatgccga tgaaatttaa
      121 tactatcatc tcagagatgg ggtcaaatat ttcaggtggg caaaggcaac agatagcact
      181 ggcacgtgca ttaataaata atcctagtat tgtaatttta gatgaagcaa ctagtgcatt
      241 agacactatt aatgaggaaa gaataacaaa gtatatacaa agtcagggtt gtactcaaat
      301 aattatagct catagattgt caacgattaa ggatgcggat attatttttg taatgaaagg
      361 tggtaagatt gttgagtcag gaaatcataa gtacttaata actcttggtg gagagtacta
      421 cagcttatat acaaaaagga aatgaggtgt aaagaaaatg aagaaagaaa atgaatatgt
      481 aattttaaca atagcctcac taggggtgat gattggaata gtgtttgcaa tttttttaga
      541 ttttccagtt gaatatggta tttctttagg cttgttgaat ggaatagtat tgggttcgct
      601 gattgtttac aaaaacaata agaattaagc ataatttttt gctgtaaact aaggagtaga
      661 gatggctata gttgaaatta taaatctaac aaaaagcttt aaagatattg aagttattca
      721 taacacttaa ataatagagc aactacagta gtagcttaaa aacatgatta aatcgctatt
      781 cttaggagta gcggtttttc tttttgttta atactctttg aaaatctctt caaaccacgt
      841 cagctttgcc ttgccgtact caagtacagc ctgcggctcg cttcctagtt tgctctttga
      901 ttttcattga gtataaaaag ggttaagtaa gtatagtaaa ttgaaataag atatgaacaa
      961 atcgattaga aaagtcaaat taatttctag aagtatgtta gaaattggtt tgaattccgc
     1021 aatcaatttg ttcagttttt atttcatttc attttattta attagatttt ccaatttttt
     1081 aattcaagct aaaaatcccc aatcgtagtg attgaggatt gagtaaataa atcttaaaca
     1141 ataccttgtg caatcatggc atttgctaca ttttcaaagg cagcaatgtt agctcctgca
     1201 aggtagtctt tatcaagacc gtatgtttct gaagtcgttt tagctgtgtt gaagatgttt
     1261 gtcatgatgt ctttgagacg gccatcaact tcttcacgag tccatgagag gcgaagactg
     1321 ttttggctca tttcaagagc tgaaacggct acaccaccag cgttggcagc ttttgcaggt
     1381 ccgtagaaga taccattttc tttgtaaact ttgatggcat caaggtcgct cggcatgttg
     1441 gcaccttcag atacacagat aacgccttga gcaaccaaac gtttagctgc ttcaccgttg
     1501 atttcgtttt gagtggcaca tggaagagca atgtcatagt ttccagcgta agtccataca
     1561 gtaccttcgt ggtaggttgc agttgctttt tcagctgcat actcagtcaa acgagcacga
     1621 cgtttttctt taacatcaac caaaagatcg aagtcgatac cattttcatc gatgacataa
     1681 ccatttgagt cagaaacaga aataacagtt gcaccgagtt cagttgcttt ttgaagagca
     1741 tattgagcaa cgttaccaga acctgaaata acgactttct taccagcaaa gctgttaccg
     1801 ttagctttga gcatttcttc agtatagtaa accaaaccgt aaccagttgc ttctggacga
     1861 atcaagctac caccaaatcc aagaggttta ccagtcaaga caccagcatc aaattggtta
     1921 agacgtttgt attgaccgta aaggtaacca atttcacgtc caccaacacc gatatcacca
     1981 gcaggtacgt caagtgatgg tccgatgtgt ttttgcaatt cagtcatgaa gctttggcag
     2041 aagcgcatca cttcagcatc tgttttacct ttaggatcga agtctgatcc acctttacct
     2101 ccaccgatag gaagtccagt caagacattt ttaaagattt gttcaaatcc gaggaatttc
     2161 aagatccctt ggtttacagt tgggtggaaa cgaagtccac ctttgtatgg tccaacagct
     2221 gagttgaatt gaacacggta accacggttt acttgaattt ttccatcacg gtcaacccaa
     2281 ggaacacgga aagaaaccac gcgctcaggc tcagtaatac gtgccaagat attttcttcg
     2341 atatactcag ggtgtttttc aaatacaggt tctaaagtgt tgaaaaattc ttcaacagct
     2401 tggaggaatt cagcctcgtg cccgttacga gctttcacag tttcaaacac gctttggata
     2461 tattctttag cagatgtcat atcgttctcc ttttattgtc atattttatt acataagaca
     2521 ttatagcaga attttttttc actgtaaaga aaaaacagaa attttctaaa aattctttca
     2581 attcagtttt tggttttttt gaaaatagat aaaaaaacga acgtttttct tggaaatatc
     2641 tttctcaaag acaaaatctt aaagtatggt atgctataag aaaagaaaat gtttagcaat
     2701 tcagaaatca cttgttaatt tatccgtgat atgttagatt tgctagtaaa attatgacca
     2761 ttttggagga aagcaatatt tataccagac taaaatcaaa aatcattata taatagtgat
     2821 atgaaatcaa ctaaagaaga aatccaagcc atcaaaacac ttttaaaaga ctctcgtaca
     2881 gctaaatatc ataaacgcct tcaaatcgtt ctatagtaaa atgaaacaag aacaggacaa
     2941 atcgattagg acagtcaaat cgatttctaa caatgtttta gaagtagagg tgtactatta
     3001 tagattcaat acactataga ctgtaatcaa acaacgattt ggcgaaatgt aaaaaatatg
     3061 aggagttcgg actcgactct ctccttcaag aaacacgtgg tggtcgtaac catgcatata
     3121 tgacagttga ggaagagaaa gcctttcttg cccgccattt gaaggctgca gaggcaggag
     3181 aatttgttac aattgatgcc ttatttcagg cttataaaaa ggagtgtgga tgaacgcctt
     3241 tttagaagag ctttcacaag cttatccaga tgattatctt ttactcgtta tggacaatgc
     3301 tatatggcat aaatcaagtg ccttaaagat tccgactaat attggctttg catttattcc
     3361 tccatacaca ccagagatga acccattgaa caagtgtgga aagagattcg taaacgtgga
     3421 tttaagaata aagcctttta aactttggaa gatgtcatga atcaactcca agatgttata
     3481 caaggactgg agaaggaggt gataaagtcc atcgttaatc ggagatggac tagaatgctt
     3541 tttgaaagca gatgagtata agtcctcgtt ttgaagcctt ggaacaggcc attgcctcca
     3601 aagatttgga aaaagtccga gaagctttta agaaaatgaa ttccacttgg accatcaatg
     3661 aaagtgtggt tcgtgacaat agtacagctc attatggacg tgttgaaaca gctatttcct
     3721 tcctgcctag tagcatggaa accgaaccta cagatgagtc tggaacatga aaacagcagt
     3781 tgatttcaag aaacaaaaaa gaacagtcga aactgttctt ttatcattat ttgagaccgt
     3841 attttttgtt gaaacgatcc acgcgtccat ctgcttgagt gaacttttga cgtccagtgt
     3901 agaatgggtg tgagtctgat gaaatttcca cacggatcaa tgggtaagtt tcgccttcga
     3961 actcaactgt ttcgttagag cgttttgttg aaccgctaag gaattggtaa ccagtagttg
     4021 tgtccatgaa gacaactggg cgatattctg gatggatatc ttttttcatt ttgcaatatt
     4081 tcctttctgc catggtctct ttgcgagcca tagattgtta ccatactagt ctatcagatt
     4141 ctgaaaagtt tggcaagtat tttatcagtt tttaagcaag ttttttaact tttggtagat
     4201 gatttcattt tcttctaggc tataggaatt agcaccactt gctagagggt ggcctccacc
     4261 atcatgctcc ttggcgattt cattgatagg atggatttta ctgcgtaagc gaacgcggta
     4321 gtggccatca gcctgttcca caaaaattcc ccagagacta acactatcaa tacgcccagg
     4381 tgcacctaca atggccgcag tttcagcatc ggttacattg tattgtttca agattttctg
     4441 actcaggata acgcgagcag caccattttc atccacttcc agatggtcgt agatgtagcc
     4501 ttgcagttta gcaattttgt agctcatagt gtccattttg cgagtgagag ccgcaaagtc
     4561 aaagttatgt tctctcaaat aagcagccag gcgaagagtc cgtgcagtgg tagaagggta
     4621 gaggaagcga cctgtatcac cgacaattcc tgcaaagagc aactcagcat cgcgatctgc
     4681 caaggctagt tgggttgttt gggcaaatag ggtaatcatc tcgctagcgc tacttgaact
     4741 agtatcgacc caagacaggt caccgtatac atcatcattt ggatggtggt caatcttaat
     4801 gagaaaatca ccttgactat agcgcttatc atcgatacga gcagtattag ctgtatcaca
     4861 gacgatgaca agtgcgcctt ggtaggctct atcttcaaca agatccatct cagccatcca
     4921 agtaagagtt ggttcatcaa aaccgacggc tttgatggtt ttttctggga aatgatgttc
     4981 cagcaaggct ttcaatccca cctgacttcc caaggcatca gggtctggtt tcatatgacg
     5041 atgaatgata atggtgttgt attctttaat tttttctaaa atttgttggc aaatctccat
     5101 aaataacctc aattctttct catttcattg tagcacaaga atttttattt ttaaaatgaa
     5161 aaagatgtga tataatggag aaagataaat tgaggaggac gatatggcat tagcaaaaat
     5221 tgtatttgcc agtatgaccg gtaataccga agaaattgca gatattgtag cagacaaatt
     5281 acgtgacttg ggcttggatg ttgatgttga tgaatgtaca actgttgacg cttcagactt
     5341 cttggaagca gacatcgcta tcgttgcgac ctatacttat ggtgatggtg aattgccaga
     5401 tgagatgatg gacttctacg aagacctagc agatctcaac ttgaatggca aaatctacgg
     5461 agtggtcggc tcaggagata ccttctacga tgaattctgt aaggctgttg atgactttga
     5521 ccgtgtcttt gtgtcaacag gagcagaaaa aggttcagag tgtgttaaag ttgatctttc
     5581 tgccgaggaa gaagatattg aacgcttgga acaattcgca gaagaattgg ctgctaaagt
     5641 aggataagca taaaagtgcg ctgatgtaat caatcagtgc atttttctta tcgagagttg
     5701 ggattttact agcctaattg atggcttttt gatacaataa ttcaaataaa ggaggagact
     5761 gtatggattt agatattatt cgtcaagaaa tcgatcaaat cgacgaccaa attgtcaaac
     5821 tgttagaaga acgaatgcat ttagttgagg gggtggttgc ttataagaaa gcttcaggta
     5881 aaccgatttt agatactaag agagaagaag ttatttttga aaaggttagg agtcgtgtag
     5941 aggacaagcg ctatcaggag actattgtcg cgactttttc gtacatactc aaacgttcgc
     6001 gtgattatca ggatcaaaat atcaaatgaa aaaagaacaa ttttatccgc taggaatttt
     6061 tctagctgct atgttgggcg gacttgtccg atatctagtt tccacctggt taccagccag
     6121 tccagacttt ccttggggca ctctctttgt caactatctg ggaattttct gcttgatttt
     6181 tcttgtcaag ggctatctgg tctataaggg gactagtaag ggcttgattt tagcactggg
     6241 gacgggtttt tgcggaggtt taacaacttt ttccagccta atgcttgata ctgtgaagct
     6301 gcttgataca gggcgttatt ttagtttagt cctgtatttg cttttgagta tcggtggagg
     6361 cctgctttta gcttactatt tggggaggaa gaaatggtaa tcgtctatct tgcaatcgcc
     6421 tgtggcttgg gagcactcgt acggtatttc ttttctcgct ataatcaagc ttctaaattg
     6481 ccactcggaa cgctcatagc taatctttta ggttgttttt taattggagt attctacaat
     6541 catgtagagt ctaaggaagt atatgctatt ctagcaacag gattttgtgg cggtttaaca
     6601 actttttcga ccttgaatga cgaacttcaa agactgctaa gtgataagaa ggtcttttat
     6661 tcttacctga ctttgactta cataggtggt ttggttgcga tttttttagg aattttgcta
     6721 taaatttctt tacttttttt tagaaatttg gtaaactata tcttgtgtgt aatggacgca
     6781 caaaaataca gtttatccgc tgaggaagat tcctcaagat tgacaaagat aggagaataa
     6841 aatgaatcca ttaatccaaa gcttgactga aggtcaactt cgtacagata tcccatcatt
     6901 ccgtcctggt gacactgttc gtgtacatgc gaaagttgtc gaaggtaacc gtgaacgtat
     6961 ccagattttt gaaggtgttg ttattgcacg taaaggtgct ggcatctctg aaaactacac
     7021 agttcgtaaa atctctaacg gtgtaggtgt tgagcgtatc ttcccaatcc acactccacg
     7081 tgttgaaaaa atcgaagttg tacgttacgg taaagtacgt cgtgcgaaat tgtactactt
     7141 gcgtgctctt caaggtaagg cagctcgtat caaagaaatc cgtcgttaat tcgactaaaa
     7201 aactctgctt tttcagcaga gtttttatct agctccctta gttcaatgga tataacaact
     7261 ccctcctaag gagtagttgc aggttcgatt cctgcagggg gcatgtaatt agatatcaaa
     7321 gaagtttgtc aaagagtctt tgatattaaa agaacgcata atatagggga ttgtctccat
     7381 aatattatgc gttttattat tgaaaaattt gggcaatcat cagataaaat tgagactata
     7441 tcgagtatat aaatgtttgt atagtcaatt tattcaaaat cgtcaagttc taaattattt
     7501 aaaggactat aacattcata tttctttaag taattgttta tttcttcagc agtggaacga
     7561 ggtaaattaa ctcttaaata gtcaatatct tccttagata aaaaatgatt tgcattcaaa
     7621 attgagaagc gaaataatgc ttcatcaaaa gcaaaatcat aatcgtcatc agataatgat
     7681 tccattaatg tttgaatatg ttttagtgag tagtcaggta tcgaatcggg ataatatact
     7741 ggataatcag tggctgaaaa attgttttct aatcctgaaa tagtaattat caaagattct
     7801 atgtaatata ttaaagcatg tttaatatta ccttcttgtt ccaaatgtct tccctgagcc
     7861 tttcgtgtgt tagataagca tccaaaatct cctgatacag tattcctatg agcttgttta
     7921 tttaagagac tccattttat atcaccaaaa gttgctttaa aagagatatt gtttttttct
     7981 ttacaataat cttccatact tatgtcttta tcatagtatg ctttgatata gtcactatgt
     8041 tcgataataa gattttgtgc ttcttttgtt agtttaaatt cgaacggaat atctaaattg
     8101 tcaatgttaa cattattaat tattcttgta attaattctg ctttttttcc agaagtagct
     8161 aaattatgtt tagataatat agtttttaat tctactactg taagatatga taaagtctta
     8221 tttttagtga agtatcctaa tttgtataat tgattgtgtg tagattcagg gtcaatttga
     8281 agagagtatt taaaatatct tgggaaatta taatttctcc ctgttttttg agtccaatct
     8341 atgagtatga gttgcccagg agtaaggcca cattctaatt cgtttaggta aaaattgtta
     8401 caatcagaat ttgtgtctct attatgatta ttttgtttta aattaaatag tttgctaaaa
     8461 aaattcattg gattttattg ctaatcaatt cttattgaaa aatgatactt ttacagtacc
     8521 catgttcgga tggcatgggc aacgccggat tcgtcatttg ttttggtgat gtatttggcg
     8581 atttttttga tttctggatt tccattttcc atgacaacgg ggtttccaac gacttccagc
     8641 atgggacggt cattttcttc atcaccgatt gccatggttt catctttggt caatccgagt
     8701 ttttcagcca agtgagtaat ggctgaaccc ttgtctacat tctttttaag gagttcgagg
     8761 tagaaaggag cagatttgtt gatggagtag cgctcgtaaa attctgctgg aattttttca
     8821 atcgcagcat cgagaatttc tggttcatcg ataaacatac atttaacaat ttctttgcca
     8881 gccatttctt caggggtacg gtagaagata ggcatgctga cgagggttga ttcgtgtaca
     8941 gtgtattttc cgatattgcg atttgcagta tagataccgt ccttggtaat ggcatgcatg
     9001 tggacaccga gcttgcgact gaggaattcc atatccagat aatcctcata ggtcaaggat
     9061 tcgctgataa tctcatggcc agtagcagtt tcttggacaa gggcaccatt gaaggtcacc
     9121 acatagtcac cttggtctct caactgcaag tcgtccagaa gtttggcaac acctgcgatg
     9181 gggcggccag ttgcaatcac gactttgaca ccagcttctt tggcatcttg gatggcagaa
     9241 aagacttcag gagtgatttc cttttggctg ttgactaggg ttccgtcaat atcgacggca
     9301 attagtttaa tactcataaa attcctcttc tagtttttat ttggggtaaa atgatcgttc
     9361 tcaatcaagt gtaaaaattg ctgggtaatg cttgcgaaga tgctgttttg gtctaacatt
     9421 tctttaggga aatagaaacg attatctccg tggcgactgc cagcaaggga ttggacgata
     9481 ggagacaggc tagagagttc ggccagttct ccattttttt gtaaaatctc aatctgtgtc
     9541 cgtggatttt gagattcggg acgatagata tcataaggga ggtcaaagtt cttatgaatg
     9601 gcagtatagt agtcgggatc aaagccgatg tcctcaacca attttctcat gctagtaagt
     9661 tgatcttggt cctcttgtga aaaggtaatg gatttaaaga ccttgcggtt gacaaagcgt
     9721 tgagataaat ctgcaagaat tttgtcagga ctagtcatcc aaagctggaa gtaggtattc
     9781 atcacgccat catccagagc cagatagtca gtcaaggtca catttttttc gaagaaaggc
     9841 aggagatgtg gggaagttcg tgcaaagaaa ttcttgtcct cagggtagag ttccttggcg
     9901 cgcttgagaa gattctgtag gagaacttcc atggcgcgtg ttgctgggtg gaaataaacc
     9961 tgcatgtaca tctggtagcg actgaggacg tagtcttcga tggcgtgcat gccattgcgc
    10021 tgaaaggcga taccattttc gacaggacga atgactcgga ggatgcgagt caggtcaaat
    10081 tccccatagg atgctcctgt aaaataggag tcgcgcaaga gatagtccat gcgatctgcg
    10141 tcaatctgac tagaaatgag ctgcacgacc tgcttattag gataggtatg gtcaatgaca
    10201 ctggccacct tttctgggaa atcaggtgcc acttgtagca ggacttggtg aatctctgtc
    10261 tcaggatttt gaataatctc ctgagtaatg gcttcatggt ctgtatcaaa gagattttca
    10321 aaagtatggg agtaggcacc atgcccaagg tcgtgtagga gagcagcggt cacggtcaag
    10381 agagactcgg caggattcca ttcctcagga tatttttctt cgaaaatctc tgtgatgcgt
    10441 cgtgcaattt catagactcc tagacagtga gagaagcgac tgtgttctcc accgtggaag
    10501 gtataactgg aagttcccag ttgtttgatc cggcgcaaac gctgaaattc ttttgtatta
    10561 atcaagtcat agatgatttg attattgaca tggatgtagt tgtgaactgg gtcacggaat
    10621 actttttcgt tcatatgacc attatagcaa aatcctgctc tttttggtaa aatagtagga
    10681 caagagacaa gaaagagggc ctgatgtgaa gattcggatg cgaaatacaa ttcagtttga
    10741 tgagcagttg gaagtgattg accagcttta tgatgtggaa gtgcatgaaa aaggagatta
    10801 tagctacctg cttttctata atgaggaaaa ggaaaaagta gtgattaaat ttcatggtca
    10861 agaacttatg atgagccgat tttctaatcc caagaccatt atgcgctttc taaaggatag
    10921 cgatagttta gcctatattc ctacacctat gggcatgcag gagtttatca tccaaacgag
    10981 ccattatcaa gttgataggc aaaagattga actagattat caactacaaa atcaagaggg
    11041 acatcctttt gccagctatc aattggaaat tacttggggc taggctcatg tctttttcaa
    11101 atttagctat ctatcttctt ggatcggctt cctagtgtgg tagattaggc taatttttgg
    11161 tataataaaa gttatggaaa tcgaaaaaac caatcgtatg aatgcgctct ttgaatttta
    11221 tgcggcgctt ttgacagata agcaaatgaa ttatatcgag ctctactacg ctgatgatta
    11281 cagccttgct gaaattgccg aggagtttgg tgtcagtcgt caggctgtct atgacaatat
    11341 caagcgaaca gaaaagattc tggaagatta tgagatgaaa ttgcacatgt actcggacta
    11401 tattgtccgc agtcagattt ttgatcagat tttggagcgc tatcccaagg atgactttct
    11461 gcaggagcag atagaaattt taacaagcat tgataataga gaataagagg aagaaaaatg
    11521 gcatttgaaa gtttaacaga acgtttgcag aacgtcttta aaaatctacg taaaaaagga
    11581 aaaatctctg aatctgatgt ccaagaggca accaaagaaa ttcgcttggc cttgctcgag
    11641 gccgacgttg ccttgcctgt tgtaaaggac tttatcaaga aagttcgtga gcgtgcagtc
    11701 gggcatgagg tcattgatac acttaatcct gcgcaacaga ttattaaaat cgttgatgag
    11761 gaactgacag ccgttttagg ttctgatacg gcagaaatta tcaagtcacc taagattcca
    11821 accatcatca tgatggttgg tttacaaggg gctggtaaaa caacctttgc tggtaaattg
    11881 gccaacaaac tcaagaaaga agaaaatgct cgtcctttga tgattgcggc ggatatttat
    11941 cgtccagctg ccattgacca gcttaagacc ttgggacaac agattgatgt gcctgtcttt
    12001 gcacttggaa cagaagtacc agctgttgag attgtacgtc aaggtttgga gcaagcccaa
    12061 actaatcata acgactatgt cttgattgat actgcgggtc gtttgcagat tgatgagctc
    12121 ctcatgaatg agcttcgtga tgtgaaagca ttggctcaac caaatgaaat cttgcttgtc
    12181 gttgatgcta tgattggtca ggaagcagcc aatgttgcgc gtgagtttaa tgctcagttg
    12241 gaagtgactg gggtcatcct taccaagatt gatggcgata ctcgtggtgg tgctgctctg
    12301 tctgttcgtc acattactgg aaaaccaatc aagttcactg gtacaggtga aaagattacg
    12361 gacattgaaa ccttccaccc agaccgcatg tctagccgta tccttggtat gggggatatg
    12421 ctcactttga ttgagaaagc ttctcaggaa tacgatgaac aaaaagccct tgaaatggct
    12481 gagaagatgc gcgaaaacac ctttgatttt aatgatttca tcgatcaatt agatcaggtg
    12541 caaaatatgg ggccgatgga agacttgctc aagatgattc caggtatggc caacaatcca
    12601 gcccttcaaa acatgaaggt ggatgaacgc cagattgctc gtaaacgtgc cattgtgtct
    12661 tcgatgacac ctgaagagcg tgaaaaccca gatttgttaa atccaagccg tcgccgtcgt
    12721 attgctgctg gttctggaaa tacattcgtc gaagtcaata aattcatcaa ggactttaac
    12781 caggctaaac agctcatgca gggtgttatg tctggggata tgaataaaat gatgaagcaa
    12841 atggggatta atccaaataa ccttcctaaa aatatgccaa atatgggagg aatggatatg
    12901 tctgcccttg aaggaatgat gggacaaggc ggtatgcctg acttatcagc tctcggagga
    12961 gcaggaatgc cagatatgag ccagatgttt ggtggcggtt tgaaaggtaa aattggtgaa
    13021 tttgccatga aacagtccat gaaacgtatg gctaacaaaa tgaagaaagc gaagaagaaa
    13081 cgcaagtaag acaagagatt gatgcaaatc tcatttgatg agaaaataaa gtaaaaattt
    13141 ctatgataaa acgtacagta tcaaggtttt agaatatctg atattatacg ttttttgatt
    13201 ttaataattt tgttaagaca cttttattat ggtatacgaa aaatccactc agctgtctga
    13261 gtggattagg tgtatttaga ctcttagtct ttattttcgt atggcaagat caagttcaag
    13321 atgattcctg tcatggctga aagggcagta cctgaaagtg taactggacc aagtttaagg
    13381 atagctcctc caagtccaag aaccaacata gcacttgcga tgatgaggtt tcgcatttga
    13441 gcgaaatcaa cacgttcttt aatcaagact ttcaaaccat tgctggcgat aaccccatag
    13501 agaaggattg acataccacc aagtacagcg tttggaatag ttgaaatcaa ggcagtgaat
    13561 ttaccaagga agctgagggc aatcgcgatg aaggcagcgt tacggataac tgagacagaa
    13621 gcgatacgag tcataccgat aacccctgta ttttctccgt aagttgtatt ggctggtcca
    13681 ccaaggaagg cagaaacaga agttgcgata ccgtcaccaa gaagagtacg gtgaagacct
    13741 ggttctttta agaattgacg accacagatt tgacccaaaa cagtatggtc tccgatatgt
    13801 tcagaaattg ttacgatagc gattggcaag atagcgatgg cttctggacc aaagtaaaga
    13861 ttgtactctt taaaggcacc acctgtgcta aatggcaagt agaaaccagg aatttcgaac
    13921 cagttggctt taagaactgg tgtaaagtca accaagccaa gagttagtgc gaaaaggtaa
    13981 ccaccgataa tggcaaagag gaatggaatg attcgtagga agccttttcc ttttgtattg
    14041 ataaaggcag caattaggaa agtaacaacg gctaccagag catttttcca atttccgtct
    14101 gctacaagac ctgcattggt aacagctgaa cctgcaagtc caagaccgat aacgatgatc
    14161 ataggaccga taatgattgg tggcaagagt ttatcaatcc attttgttcc tacaaatcgg
    14221 atgctggtag caacaaggac atagaccaaa ccagtcaaga taacccctgt ttgggcagca
    14281 gatacatccc cccccatttc tttcatagcc agtgacatag ctgtgataaa ggcaaatgaa
    14341 gaacctagat aaactggaac tttaaaacca gtagcaatca tgtagatgag tgttccaaca
    14401 cctgaagcaa aaagggcaac agatacaggc attcccaaaa tcaatggtac caagatggtc
    14461 gcaccaaaca tggcgaaaac gtgttggaaa ctaaggagaa ttccttttcc agccgaagga
    14521 cgttggtcaa cgtctagtaa caaatcaaca gttgattctt gtttcatata aacctcactt
    14581 ttgggcatca aaaaagagcc cattatttta cagcaatagg ccctcagagt aagacttctt
    14641 taaaatttag attttaaaga gttttaaata tttctgcgtc ttcgtcacct cacgggatga
    14701 cattaaaaac ctttgcttag gatagtatag cagaaaaaaa tgattttgta aatcattttt
    14761 tcccgagcct agaaataaaa gagcgaggct gattttgtaa atcatttttt cccgagccta
    14821 gaaataaaag agcgaggctg attttgtaaa catttgttta ctaaaaaatt taaagtgggc
    14881 gtttatttgg cataccagcc ttacgcggat atttatttgg tgtttctttt ttcttttcta
    14941 ccactgtgat atagcgcgga tctctattcg gtagggcgta gctgagattg tcttcgacct
    15001 tactaaaaag gagattgagg gcattcttag cttctaataa ttcctcaggc gcattgctgg
    15061 ccttgagtgc caatagtttt ccaccaacct taaggtaggg aatggtcaat tcagatagga
    15121 cctgcatacg ggcaaccgca cgagctgtta caaaatcata ttgagcacgg aagttcttgt
    15181 cttgggcaaa atcttcggca cgtccgtggt agaaatgaac tccgttcaaa tccagttctt
    15241 gagccaagag ttgtaggaag ttgatgcgct tattgagtga atcaataatg gtcacatcta
    15301 actccggata gagaattttc attggtagac taggaaatcc tgccccagcc ccgatatcaa
    15361 gaagtttgat agtttcattg ggaatcaaac cttgaagaat gggtgcaatc gaatcgtaaa
    15421 aatgtttgag ataaacttct tccttgtccg taatcgccgt caaattaatc ttctcattcc
    15481 actcgaccaa gagctcaaaa taacgttcaa attgttcttt ttgctggtcc gaaagtggaa
    15541 gattctgctc ggcaagcaag ttgtaaaatg tttttggttt catagttatt tccttcttta
    15601 gtatcatctt attttaccac aatcatagaa aatttgatat actggtacta atctaaaagc
    15661 agaaaggact tatattatga cttggattat tcttggagtt atcgctctta ttgttatttt
    15721 tgtgattgtt agctataacg gtttggttaa aaatcgtatg caaaccaagg aggcttggag
    15781 tcagattgat gttcagttga aacgtcgaaa tgacctcttg ccaaacttga ttgagactgt
    15841 aaaaggttat gccaaatatg aaggttctac ccttgaaaag gtggcagaac tacgtaacca
    15901 agtggcggca gcgacttcac cagcagaagc tatgaaagcc agtgatgccc tcactcgtca
    15961 ggtttcaggt atttttgcag ttgcagaaag ctatccagat ttgaaagcta gtgctaactt
    16021 tgttaaattg caagaggagt tgacaaacac agaaaataaa atttcttact ctcgtcaact
    16081 ctataacagt gttgtcagca actacaatgt aaaattagaa actttcccga gcaatattat
    16141 cgctggaatg tttggattta aagcggcaga tttccttcaa acatctgaag aggaaaagtc
    16201 ggttcctaaa gttgatttta gcggtttagg tgactaagat gttgtttgat caaattgcaa
    16261 gcaataaacg aaaaacctgg attttgttgc tggtattttt cctactctta gctcttgttg
    16321 gttatgcggt tggttatctc tttataagat ctggacttgg tggtttggtt atcgcactga
    16381 ttatcggctt tatctacgct ttgtctatga tttttcaatc gacagagatt gtcatgtcca
    16441 tgaatggagc gcgtgaggtg gatgagcaaa cggcaccaga cctctaccat gtagtggaag
    16501 atatggctct ggtcgctcag attcctatgc cccgtgtttt catcattgat gatccagcct
    16561 taaatgcctt tgcgacaggt tctaatcctc aaaatgcggc tgttgctgcg acttcaggtc
    16621 tactagctat catgaatcgt gaagaactag aagctgttat gggacatgaa gtcagtcata
    16681 ttcgtaatta tgatatccgt atttcgacta ttgcagttgc ccttgctagt gctatcacca
    16741 tgctttctag tatggcaggt cgtatgatgt ggtggggtgg agcaggtcgc agacgaagtg
    16801 atgatgaccg agatggaaat ggtcttgaaa tcattatgct agtggtttcc ctactagcta
    16861 ttgtactggc acctctcgct gcaaccttgg ttcagctcgc tatttctcgt cagagggaat
    16921 ttctggcaga tgcatctagt gtcgagctga ctcgcaatcc ccagggaatg attaatgccc
    16981 tagataagtt ggacaatagc aaacctatga gtcgccacgt cgatgatgct agcagtgccc
    17041 tttatatcaa tgatcctaag aaaggtgggg ggttccaaaa actcttttat acccacccac
    17101 ctatctcaga acggattgaa cgtttaaaac agatgtaaaa gaatccagag gtcgtctctg
    17161 gatttttgct atgttgcaaa tttataaatc ttctaaatta actagcttca aaccgtgttc
    17221 tgtcatgcga tagatgatcg agcagacttc ttttaagaaa cgacggtcat gcgaaacagt
    17281 gatgagaccg cctggatagg ttgcaaagag ttttctgatt tggggttgag aagtgggaga
    17341 aaagtttcgt gtgggttcat ccagcaggag aaagtttggt ttgcgcagaa ctagatccaa
    17401 aagcaggagt tttccctgtt gtccgccaga taaggagcga atttgatgct gcatttctgg
    17461 ataactgaaa ttgagactgg ctaggtgaga ttggattttc tgaagttcct ctttttcccc
    17521 agttttgctg atataagcta ttgaggataa atccaattgc agttttttgt ggtaatcttg
    17581 tggcataaaa ccaagtgaaa tctctctttt atcattcaga agttgctgta atttggctaa
    17641 cagagttgat ttcccaacac catttgggcc gatgataccg attttttctt ggccacggac
    17701 agttagttgc agttcctgag ccaaaacacg gtcgtcaatg gacaaatttt ctttttccag
    17761 ttggactaag actttagaag ctggtaatgg ttggatgtct gaaaagaaaa gttggatttg
    17821 ttcctcttca agtggctttt gagtcatgga ctgagctgtc ttttcgtagc gtttttcttg
    17881 tgagaggaca gttttcatct ttttagccaa taggcgaccg gcagtactat ctttggtagc
    17941 tcgaagcgca gtttctacat tttgcttaac tctccgatgt ttttccatgg ttttatcgta
    18001 ggctctttgg ttgttagcag cttgctgact ttgtttggca aaattagcct ttctctgctc
    18061 actatagcta tcatagtcta aatgctctac tagcgtttcc gcttctttac ggtgtttgac
    18121 cagtcgcaag tgaacaatag tgtctgccgt ttcagaaaga aagtcttcat catgggaaat
    18181 gaaaataacg gtttgcctgg tcttttgaat ctggcctttt agccaatcaa ctgtctcaag
    18241 gtctaggtca tttgaaggtt catctaaaaa tagaatctca aagggtttgg ctaactcatg
    18301 gataagctga attttcaaag cttcgccccc tgatagattg ccaatctctt ggtcacttgc
    18361 gaaacgattg ctatcaaaat gcaattcctc cgccaaacga tagaggatac tgtagtctaa
    18421 atcaatagaa tctaaaaaga agtagtcgtg taaagttttc ttttttaggt cctcagggac
    18481 tttttgagga atgtaggcca gtgactgata atcagactgg atgtctccct tgatagtgaa
    18541 atcagacaaa tcttccccca ttaaagtttt aagtaaggtt gatttaccat ttccttcttc
    18601 gccaataata gctacctttt ccccgtcttg tatggtcatg cttaggtcag agacaaggtc
    18661 tcgtaaatct ttgttttgtg tgatggtcag gtgattgatt tttatcatac tattgccctt
    18721 tctagaatgt cgatagtgca taacaaaaag ctctacttta cctagtagag cccaaagtct
    18781 atgtcaaaaa aactctatta acatgccaga aaaagagcat aaaagagcac acaaaaagag
    18841 acaaaaacaa gatctactaa ataaaggttc tttatttgat agacttagtt gttcatgtct
    18901 cccttacctc cgagtattag tatctttata ctatactttt aaggaaattt tgtcaacaga
    18961 aaactggaaa ttctatgctc taaaatccaa aaacaggtcc atagagactt agtacgtgtt
    19021 tgacatgctc gtaatggatt ttatcatagt ttcgccaagc agtgcgtgct tgatcgttta
    19081 gttttaggct acccagtcca atcagaggac tggtgggttg gtaaaatttc tcaagatcaa
    19141 ttaagatact gttgttcaac ttttccgttt ttttgagctc ttgcatagta gtgtttagca
    19201 gctcttgtag tcgaatatca tctgccgtac cctgtttaca gttttggtag cttttattta
    19261 acttggatag gagttgaatg agtttcttgt cttccatgtc ttccatatga gcatcctcct
    19321 tgatctgatg tactctttcc ctatagtata gcactaaaaa ataaaactgt catagtaaat
    19381 atgttaaaat tttgaatttt aattacaaag tttggtgtgc tgatttgtag ccttttcatg
    19441 gtataatcaa gagagtaaat ctttatggag gaagtatgaa attaaatatt caagaaattc
    19501 gtaagcagtc tgaaggtttg aactttgaac aaacgttaga tttagttgat gacctgcgtg
    19561 cacgtaatca agaaatttta gatgtaaaag atatccttgc agttgggaaa gtacaatatg
    19621 aagaccgtat gtatttctta gattatcaac tatcttatac cattgttctt gcttcgagtc
    19681 gcagtatgga gccagttgag ttagttgaat cttatccagt cacggaagtt ttcatggaag
    19741 gcgcaactaa ccagctagat caagaagttt tagatgatga cttggtcttg cccattgaaa
    19801 atggggagct tgaccttgct gagagtgtat cagacaatat cctgctaaac attcctatca
    19861 aggtcttgac ggctgaagaa gaagctggtc aaggatttat ctcaggaaat gactggcaaa
    19921 tcatgacaga ggaagaatac caagctcaac aagcagtaaa gaaagaagaa aacagtcctt
    19981 ttgctggctt acaaggacta tttgacggag atgaataatg gtcttgtcaa aaaaacgagc
    20041 acgaaaggtg ctagaagaaa tcattgccct cttcccagat gccaagccta gtcttgattt
    20101 taccaatcat tttgaactcc tggttgcggt catgttatca gcccagacga cagatgcagc
    20161 ggtaaataag gccacaccag gtctctttgt tgcctttcca acaccccaag ctatgtctgt
    20221 agcgacagag agtgagattg cttcacatat ttctcgcttg ggattgtatc ggaataaagc
    20281 taaattcctt aaaaaatgtg cccaacagtt actagacgat tttgatggtc aagtccctca
    20341 gacacgtgaa gaattggaga gtttggcagg tgttggtcgc aagacagcca atgttgtcat
    20401 gagtgtagga tttgggattc cagcctttgc agtggatact catgtggagc gtatttgcaa
    20461 acaccacgat attgtcaaaa aatcagcgac gccacttgag gtggaaaagc gggtcatgga
    20521 tatcttgccg cctgagcagt ggttagctgc ccatcaggcc atgatttatt ttggaagagc
    20581 catttgccat ccaaaaaatc cagagtgtga ccagtaccca caattatatg attttagcaa
    20641 tttgtaagat gctacattga aactttttgc ttgattttaa gcatgctttg tgctatagta
    20701 aatgataact aaatattcct ttaaacctgt cccgtgaggc aggcaaggag cgcgataaag
    20761 tagaagggtg aagtctatac tgtttgcagt agggctcgct tggctataaa tttcaagtct
    20821 ccttgtttaa ggagactttt ctttttggag gtttgtcatg aaaacaaaag aagttgtaga
    20881 cgaattgacc gtcaaacgag cgattacgcg tattacttat gagattatcg aacgcaacaa
    20941 agatttgaat aagatcgtct tggctggtat taaaactcgt ggtgtcttta ttgcccaccg
    21001 aatccaagaa cgtttgaagc agttagaaaa tctttcagtt cctgttgtgg aattggatac
    21061 taaacctttc cgtgatgatg ttaaaagtgg agaagatact tctttggttt ctgtcgatgt
    21121 gacagaccgc gaagttatct tggtggatga tgtgctctat acaggtcgta ccatccgtgc
    21181 tgctattgat aatattgtcg gtcatggtcg tcctgcgcgt gtgagtttag cagttctagt
    21241 cgatcgtgga catagagaat tgccaatccg tccagattac gttggaaaaa atatcccaac
    21301 cagtcgttct gaagaaatca tcgtagagat gacagaactt gatgaccaag acagagttct
    21361 gattactgaa gaagcttaga aagttaaagg agtagccatg tcagaaaatc aacaagcatt
    21421 gaaccatgtg gtgtccatgg aagacctcac tgtcgatcaa gtaatgaaat tgatcaagcg
    21481 aggaattgag tttaaaaatg gagcccagct tccctatgaa gaccatccga ttgtttccaa
    21541 tctcttcttt gaggattcta cacggacaca taagtccttt gaagtcgcag agattaaact
    21601 tggattggaa cgacttgact ttgatgtgaa gactagttcg gttaataagg gtgagacact
    21661 ttatgacacc attttgactc tgtctgcttt aggagtggat gtctgtgtga ttcgccatcc
    21721 agaggtcgac tactatagag aattgattgc tagtccaacg attacgactt ccatcatcaa
    21781 tggtggagat ggttcgggcc aacaccctag ccagagcttg cttgatttga tgaccattta
    21841 tgaggaattt ggccactttg agggtcttaa agttgctatt gcaggtgact tggaccactc
    21901 acgcgttgcc aaatccaata tgcagatttt gaaacgcttg ggagctgaac tctttttcgc
    21961 tggacctgag gaatggagaa gtcaagagtt tgcagactat ggaaagtttg taaccattga
    22021 tgaaatcatt gatcaggttg atgtcatgat gtttctccgt gtgcaacacg aacgccatga
    22081 tagtggagct gtattttcaa aagaagacta tcatgcccaa catggcttga ctcaagaacg
    22141 ttacgatcgt ttgaaagaaa cagcaatcct catgcaccca gctccaatca atcgtgatgt
    22201 agaaatagca gaccacttgg ttgaagcacc aaaatcacgg attgtccaac aaatgaccaa
    22261 tggtgtcttt gttcgaatgg caatcttaga atccgtacta gcgagtagaa acgccaacta
    22321 aaacacaaga cgttaaaaga cgccagtgag cgtccacgag aggtgaaaat atgacaaaaa
    22381 gaattctagt attagaagat ggcacagttt ttgaaggcaa ggccttcgga gcagatattg
    22441 atgtaacagg cgaaatcgtc tttaatacag ggatgaccgg ctaccaagaa tccattacag
    22501 accagtctta taatggacaa atcttgacct ttacttatcc tttggtagga aattatggta
    22561 ttaatcgtga tgattatgaa tccattattc caacttgtaa gggagtcgtt gtttttgaag
    22621 aagcgcgtag agctagcaac tggcgcaacc aaatgacctt ggatgaattt ttgaaagcca
    22681 agaaaattcc agggatttca ggaattgata cgcgtgctct taccaagatt atccgtaagc
    22741 atggtactat gcgtgcaacc ttgacccatg ttggggacag tatggaccat gtgacggacc
    22801 agctccaagc aacagtttta ccgacagaca atatcaaaca ggtttctact aaaacgtctt
    22861 atccagctcc aggagttggt ttgagcgtgg tgctagtgga ctttggtctc aagcactcaa
    22921 tcctacgtga actttctaaa cgcaactgta acgtgacagt tgttccttat tcgacaacgg
    22981 ctgaagaaat tctccatctc aatcctgatg gagttatgtt gtcaaatggt ccaggtaacc
    23041 cagaagacgt tccacaagca ctcgacatga ttcgcggtgt acaaggaaaa attccaatct
    23101 ttggtatttg tatgggacac caactctttg caatggcaaa cggggctaag acctataaga
    23161 tgaagtttgg ccaccgtgga ttcaaccatg cggtacgtga aatcgcaaca ggacgagtag
    23221 acttcaccag ccagaaccat ggttatgcag tcagccgcga ggatttgcca gagcacttga
    23281 ttattaccca cgaagaaatc aatgacaagt cagtggaagg tgtgcgccac agataccaac
    23341 ctgctttctc tgttcaatac cacccagatg cagctcctgg gccacacgac gctagctacc
    23401 tatttgacga gtttatcgag atgatggaag tttttaaaca atcaaactaa gaatgagtaa
    23461 aagctcgtcg gagaatttat gtaactgaac atggacggaa agctcagaat ttagagaaac
    23521 caacttggat tgtcaatcct tccttgattt cctaaaattc aatcgctttc tagtcgtcct
    23581 ttgtatctta tttaatgtcg ccctgagagg cgacgaatag aaaggagaag atacattgtt
    23641 cgcggaagtg aacacgccct aagaactgtg tgaaaaagat aaacatcgtc ttgacgctga
    23701 aggcgtctgc gccgagtttc ctattttcac tgtgttcttt acgggctttg tatcataaac
    23761 tatgcctaaa cgtactgata ttcaaaaaat tatggtgatt ggttctggtc cgattattat
    23821 tggtcaggct gctgagtttg actacgctgg gactcaggct tgcttgtcgt tgaaagagga
    23881 aggttatgag gttgttttgg ttaactcaaa tcctgcaacc atcatgacgg acaaggaaat
    23941 tgctgacaag gtttacattg aaccgattac acttgagttt gtgacacgta ttcttcgtaa
    24001 ggaacgtcca gatgccttgc taccaacact cggtggtcag acaggtctca acatggccat
    24061 ggaattgtct aaaaatggta tcttagatga gcttggcgtt gaacttctgg gtaccaaatt
    24121 atctgccatt gaccaagcgg aggaccgtga cctctttaaa caattgatgg aagagcttga
    24181 acaacccatt ccagaatctg aaattgttaa cacagtagaa gaagcagttg cctttgcagc
    24241 gacaattggc tacccagtca tcgttcgtcc agcctttacc ctcggtggta ctggtggtgg
    24301 tatgtgtgcc aacgagaaag aattgcgtga aatcactgaa aatggtttga aattgtcacc
    24361 tgttacccaa tgtttgattg agcgttcgat tgccggtttc aaggaaattg aatacgaagt
    24421 gatgcgtgac tcagctgaca atgccttggt tgtttgtaac atggaaaact ttgacccagt
    24481 tgggattcac acgggggatt ccattgtatt tgcccctgcg caaaccatgt cagactatga
    24541 aaaccaaatg cttcgtgatg cgagcttgag cattattcgt gccctcaaga ttgaaggtgg
    24601 atgtaatgtt cagctagctc ttgatcctaa cagcttcaag tattatgtta tcgaagtaaa
    24661 ccctcgtgta tcacgttcgt cagcccttgc ttctaaagcg acaggatatc cgattgctaa
    24721 gttggctgcc aagattgcag taggtttgac cttggatgag gttataaacc cagttacagg
    24781 ttcaacctat gccatgtttg aaccagccct tgactacgta gttgctaaga ttccacgttt
    24841 cccatttgac aagtttgaaa agggtgaacg ccgtctcggt acacaaatga aggcgactgg
    24901 agaagtcatg gcaatcggtc gtaacatcga ggaatctctt ctcaaggcct gccgctccct
    24961 tgaaattggg gtgcaccaca atgaaatacc tgaacttgca gcagtttctg atgatgcctt
    25021 gattgaaaag gttgtcaaag cccaagatga ccgtctcttc tacgtatcag aagcaattcg
    25081 tcgtggctac acacctgaag aaattgcaga gcttacaaaa attgatatct tctatcttga
    25141 taaactcttg catatctttg aaattgagca agaattgggt gctcatccac aagatctaga
    25201 agttttgaaa acagccaaac ttaatggttt ttcagaccgt aagattgctg aactctgggg
    25261 aacgactgat gatcaagttc gccaacttcg cttggaaaac aagattgttc cagtttataa
    25321 gatggtagac acttgtgcgg cagagttcga ctccgaaacg ccatatttct attcaaccta
    25381 tggttgggaa aatgaatcta tcagatctga taaagaatct gtacttgtcc taggttcagg
    25441 tccaatccgt attggtcaag gggttgagtt tgactacgca accgttcact ctgttaaggc
    25501 tatccaggca gctggttatg aagctatcat catgaactca aacccagaga ccgtttcaac
    25561 agacttctct gtatcagata agctttactt tgagccattg acattcgaag atgttatgaa
    25621 cgtcattgac ttggaacaac caaagggagt tatcgttcag ttcggtggtc aaacagccat
    25681 caaccttgcg gagccattgg caaaagcagg tgtgaccatc cttggtacac aggttgctga
    25741 cctagatcgt gccgaagacc gtgacctctt cgagcaagct ctcaaagaat tggatattcc
    25801 acagccacca ggacaaacag ctaccaatga agaagaagca gctcttgcag ctcgcaagat
    25861 tggcttccca gttcttgtcc gcccatctta tgtacttggt ggacgtgcca tggaaatcgt
    25921 tgaaaacgaa gaagaccttc gttcttacat gcgaactgct gttaaggcta gtccagacca
    25981 cccagttctt gtcgactctt atatcgttgg gcaagagtgc gaagttgatg ccatttcaga
    26041 tggtaaaaat gtactcattc ctggtatcat ggagcatatc gaacgtgctg gtgtccactc
    26101 aggtgactca atggctgttt acccaccaca aaccttgtcg caaaaggttc aggagaccat
    26161 cgcagactac accaaacgct tagcaatcgg tcttcactgc cttggaatga tgaacatcca
    26221 gtttgttatc aaggatgaaa aagtctacgt tattgaggtc aatccacgtg ccagccgtac
    26281 tgttccattc ctatctaagg taaccaatat tcctatggct caagtagcga ccaaactcat
    26341 tcttggtcaa agtttatcag aacttggcta ccaaaatgga ctttaccctg aaagcacccg
    26401 tgttcatatc aaggcacctg tcttctcctt taccaaacta gctaaggtag acagcttgct
    26461 cggtcctgaa atgaagtcaa caggtgaagt tatgggttct gatgctactt tggaaaaagc
    26521 tctctataaa gcctttgaag cttcttatct acacttgcca acttttggta atgtcgtctt
    26581 taccatcgct gatgatgcca aagaagaagc cttgaacttg gctcgtcgtt tccaaaacat
    26641 tggttatgga atccttgcga cagaagggac agcagccttc tttgctagcc atggcttgca
    26701 agcccaacct gttggtaaga ttggtgatga cgataaggat atcccaagtt ttgtacgcaa
    26761 aggaagaatt caagctatca ttaacacagt aggaacaaaa cgaactgctg acgaagatgg
    26821 tgagcaaatt cgtcgttcag ccattgaaca cggggtgccc ctcttcacag cgctagatac
    26881 agctaatgcc atgcttaagg tacttgaaag tcgtagcttt gttacagaag cgatttaaat
    26941 agaaaaataa gatatagcag actgaattta gaacagtaca caggaatact aaaatatttc
    27001 tagaaattaa tttgaatttt ctaattgatt tgttcgcatc ttatttcaat ctactataga
    27061 aaaaagtctt taaaattata aaacgcatca tatcaaggtt tttcaaaaac cttgatatga
    27121 tgcgttttat tgtgggaata tgtatttcat tttctactaa aattatgttt ttgaataacc
    27181 tctatcttag tagtttgtat aatccccctc aatcagtttt tgcgataagc tttaatgcta
    27241 tgactatacc actcttgcat ttcttttgat ggtggtgtca tataatcgcc atacatctgg
    27301 gttaaaaatt ggtcatattt tttgggaaca ggcaacatac ggccctcaaa ctcagttaaa
    27361 atcagttctt taaaggtatc aactgggaag atttctttca tcccttcctt accgatccca
    27421 actcctcctt catattgagg aatgttggtt acagcatttt tgactagttg atcaattttc
    27481 ttgtaaaagt agcgaggatt gacaaatcgg agagcgtacc agctacataa tctaagaaaa
    27541 tcttttagtt tgctatcacc gtgaactgct cgtgattttt tgatgtaagc tagttgacga
    27601 agggccacat acttatagct cttgtcgaca atgctcaagt ctgtaaattg atcaattggg
    27661 aagacatcga tgaaaaggct ggtatcatga cgcttgtact taacatggtc ttctataaca
    27721 gtagaagtat ccaaaatcga tgcgaaatta tggaagtacc aagaagatgt atcgtaggaa
    27781 agaaccttgt agcgagggtg attttcttct tcaataatct tcagtaaacg ctcataatcc
    27841 tcacgataaa gggaaatatc aatatcatca tcccaaggaa tcataccttt gtggcggatg
    27901 gctccaagca tggttccata actgagaaaa taaggaatat catgtttctt acaagtctca
    27961 tcaatatagt ccagcagggc tagttgaatt tctttaattt cttttttttc taaatattgc
    28021 atcctaatcc tccaatttat aagcgtgaaa ttcatgactg tagaagcgtt tttcttctgg
    28081 tggtagggtc atataatctc cataaaattg tgtcaaaata gtatcaaatt tttcaggtgc
    28141 aggaaggctt aaattctcaa agggtaaatc gattgtttta tcaaaggtag cacttgggaa
    28201 gacttccttt tccttaaatt ttgaaggaat aaaagccata tactgcccat tttcacgact
    28261 atatttttga atttctttct cgattttatt tgcaaaataa cgaggagaaa ccagtcgaag
    28321 gagcaaccaa aaggctgttc gtatccaatc ttttaaaagg ctatccttat agacaatatt
    28381 tttatgttta ctgaaagaca gcagtttgaa gctttctagt ttataacaag tatcaatgac
    28441 cttaggatca tcaaagcgat ccatagggaa aatatcgata aagataccag actcataggt
    28501 ttttgtattt cgagtatcaa taattttagt cgtactgtcg gttatcttga taaagttgtt
    28561 aaagtagttc ttatcagttt ctaaggatag gagcttatac ttgctttttt ccttttgaaa
    28621 aatgttaata aatcgttggt agtcttctct aggcatggat aaatcaatat cgtcgtccca
    28681 agggataaag ccctcatgtc gaaccgcccc aatcagagta ccgtagttaa taatatagtt
    28741 gatattgtgc tttttacaga gagtatcaat ataattcaaa atttctaatt caatttgttt
    28801 ggcatcttca acggttagtt gtttcatttt aaactcctaa gattttttaa atttattttt
    28861 taaggctagg acatggttta aaaattcata gaaaatgcta tcttttgtga agacaagtag
    28921 actaatataa gagatagctg atagcaagac aatcaaacca gtattaatca aaaatggcaa
    28981 attaatgacc atatccacag gatacacgaa attaatcagg aaataaattg ctacaaagga
    29041 aagtgaaaag agagagtatc gaacagtata gctaaagata tgtcccaagt ggatgagttg
    29101 ttttctatgg atgaaaatga tatagaaaac aagtagagaa gcctctgata acatagttgt
    29161 cagtaagtag tattcgggag ccacgatatg gttgaaaaag aggagactat tcaagcccaa
    29221 attgagtagc ccagcaaaga ctgtatagac tgtgatacgt ttttcatagc cattggtaaa
    29281 gagaatttgg gaaccaagaa tggtatctaa ggccaggata atcgtacgaa aagcgaagag
    29341 agaggtcaag atgtcgcctc cgatatattt ttcactaccg taaagtagga tggcatttgg
    29401 tcctaaaacc atgagtccaa aactcagtgg aatgataaag aagttaaaga ttcgactacc
    29461 tctattaacc agagaaacat aggcttcttt gtctcctttc cccagatagt aactgagacg
    29521 aggcacactc actccaattg cacctgttac aaccccagct ataacggtca caattcgctg
    29581 agctatggta tagtaactaa cgttgacatc aatccctgtt ttaacgagga agaggcgatc
    29641 taaaaaagtg aagagcatat tggcattggc aaagactaac atggctgtca gagggagaaa
    29701 gagtggttta aaatcactta ggtgaatctt aacaagtttg atgtctcttt taatccaaaa
    29761 ataactaatc aggtagttaa tcagcgtcga taaactcatc acaagtgtat agacaacaat
    29821 atcgtgttca tttttaacaa ataagaaaat agagaccagc atcaggatac ggatgaaggc
    29881 agttttgtaa aagagaaaac tgtaattttc cagagcttca ttgacccatt cgattgaaaa
    29941 aatctgggca atgagttgaa tccccataac aaggtagacc tttttgacga ttggattatc
    30001 agtaaagaag agaggatagg ctaggatata gacagcagtg gtcaaaatcg tacaagcgat
    30061 gcacaaataa aaaagactag aaaaggttct gttaagatct tttttgttat ccttgacatt
    30121 actgatagcc cttaaaccgt agttatagac accataagtt gcaaagggca agaaaaatga
    30181 caaaatagtg tcgactgagt tgaagtaacc atagtcagtt cggtccaaga cacgcgcgac
    30241 ataggttcca gttaggatgg gaaaaataat attcaagaca cgaattccca tgtaagatag
    30301 agcatttaat tttatacttt tcattcaatt tacctcgttt ttcattatat cataaagtta
    30361 gctaataaga aatgaagggc agtaagtcaa gtaatcactt tgaagtttca aatcttaagt
    30421 tttaagtttt ctttaaggaa agtatattat tctgaaggac tctaaaattt cgcagccatt
    30481 tattagtaat tgctacagaa ttcctagtca ttactagaaa tggactagtt tctttgaata
    30541 atagaactgc ataattctcc tattctagaa ggggaggacc agtatttctt ttatgatagg
    30601 actagattgt ggtataatag agagaataag tttttttagt aagacaaagg agaaaataga
    30661 tgatttatgc aggaattctt gccggtggaa ctggcacacg catggggatc agtaacttgc
    30721 caaaacaatt tttagagcta ggtgatcgac ctattttgat tcatacaatt gaaaaatttg
    30781 tcttggagcc aagtattgaa aaaattgtag ttggtgttca tggagactgg gtttctcatg
    30841 cagaagatct tgtagataaa tatcttcctc tttataagga acgtatcatc attacaaagg
    30901 gtggtgctga ccgcaataca agtattaaga aaatcattga agccattgat gcttatcgtc
    30961 cgcttactcc agaggatatc gttgttaccc acgattctgt tcgtccattt attacacttc
    31021 gcatgattca ggacagtatc caacttgccc aaaatcatga cgcagtggac acagtggtag
    31081 aagcggttga tactatcgtt gaaagtacca atggtcaatt tattacagat attccaaatc
    31141 gtgctcacct ttatcaagga caaacacctc aaacattccg ttgcaaggac ttcatggacc
    31201 tttatggatc tctttctgat gaagagaagg aaatcttgac agatgcatgt aaaatctttg
    31261 tgatcaaagg aaaagatgtg gccttggcca aaggtgaata ctcaaatctg aagattacaa
    31321 ccgtaacaga tttgaagatt gcaaaaagta tgattgagaa agactagtaa aatgattaat
    31381 caaatttatc aactaactaa gcctaagttt atcaatgtca aatatcagga agaggctatt
    31441 gaccaagaga atcatatcct tatccgtccc aactacatgg ctgtctgtca tgcggatcag
    31501 cgttactatc agggaaaacg tgatcccaag attttgaata aaaagcttcc aatggcaatg
    31561 attcacgagt catgtggaac cgtcatttct gacccgaccg gaacctacga ggttggtcaa
    31621 aaagttgtca tgattcccaa tcagtctcct atgcagagtg atgaagaatt ctatgaaaac
    31681 tacatgacag ggacccattt cttgtctagt ggatttgatg gctttatgag agagtttgtt
    31741 tctctcccta aagatcgtgt ggtggcttat gatgctattg aagatacggt tgcagccatt
    31801 acagagtttg tcagtgtggg catgcacgct atgaatcgtc tattgactct tgctcatagc
    31861 aagcgggagc ggatcgccgt tattggagat ggaagtttag cttttgtggt tgccaatatt
    31921 atcaactata ctttgccaga agcagagatt gtggttattg gtcgtcattg ggaaaagttg
    31981 gaactcttct catttgccaa agaatgctat attacggata atattcctga agagttggcc
    32041 tttgaccatg cttttgaatg ttgtggtggt gatggtactg gaccagctat taatgacttg
    32101 attcgctaca ttcgtcctca gggaacgatt ctcatgatgg gagttagcga atataaagtc
    32161 aatctcaata ctcgcgatgc cttagaaaag ggcttgattt tggttgggtc atctcgttct
    32221 ggtcgcattg attttaaaaa tgctatccaa atgatggaag tcaagaaatt tgccaatcgt
    32281 cttaaaaata tcctttatct agaagaacct gtaagagaaa ttaaagatat tcatcgtgtc
    32341 tttgcaaccg atttaaacac agcctttaaa acagtgttta agtgggaagt ataagtactg
    32401 gaggttaatt gtggagaaaa tcattaaaga aaaaatttct tccttactta gtcaagaaga
    32461 ggaagtcctc agtgttgaac aactgggtgg aatgaccaat caaaactatt tggccaaaac
    32521 aacaaataag caatacattg ttaaattctt tggtaaaggg acagaaaagc ttatcaatcg
    32581 acaagatgaa aagtacaatc ttgaactact aaaggattta ggcttagatg taaaaaatta
    32641 tctttttgat attgaagctg gtatcaaagt aaatgagtat atcgaatctg cgattacgct
    32701 tgattcaacg tcaatcaaga ccaagttcga caaaattgct ccaatattac aaactattca
    32761 tacgtctgct aaggaattaa gaggagaatt tgctcctttt gaagaaatca aaaaatacga
    32821 atccttgatt gaagaacaaa ttccttatgc caactatgaa tctgttagaa atgcagtctt
    32881 ctccttagag aaaagactgg ctgacttagg tgttgacaga aaatcttgtc atatcgattt
    32941 ggtgcctgaa aactttatcg aatcacctca aggacgactt tatttgattg actgggaata
    33001 ttcatcaatg aatgatccaa tgtgggattt ggctgccctc tttttagagt ctgaattcac
    33061 ttcccaagag gaagaaactt tcttatctca ctatgagagt gaccaaacac cggtttctca
    33121 tgaaaagatt gctatttata aaattttaca agatactatt tggagtctat ggactgtcta
    33181 taaggaagag caaggtgaag attttggtga ctatggtgtg aatcgttacc aaagagctgt
    33241 taaaggtttg gcttcttatg gaggttcaga tgaaaagtaa aaacggagtt ccttttggcc
    33301 ttctctcagg tattttctgg ggcttgggtc taacggttag tgcttatatc ttttcgattt
    33361 ttacagattt gtcacccttt gtggtggctg cagctcatga ttttttgagc atctttatct
    33421 tactagcttt tctcttggta aaagaaggga aagttcgcct ctcaattttc ttaaatattc
    33481 gcaatgtcag tgttatcatc ggagccttgc tagcaggccc tatcggtatg caggccaatc
    33541 tttatgcagt taagtatatc ggaagttctt tagcttcatc tgtatcggct atttaccctg
    33601 cgatttcagt tctattggct ttcttctttt tgaagcacaa gatttcgaaa aatactgtat
    33661 ttgggattgt cttgattatt ggagggatta ttgcccagac ctataaagtt gaacaggtta
    33721 attctttcta cattgggatt ctttgtgctt tggtttgtgc tattgcatgg ggaagtgaga
    33781 gtgttcttag ctcttttgcc atggaaagtg aattgagtga aatcgaagcc ctcttaatcc
    33841 gtcaagtaac ttcgttcttg tcctatcttg tgattgtgct cttctctcat cagtcattta
    33901 ctgcagtagc caatggacaa ttgctaggtc tcatgattgt ttttgcagcc tttgatatga
    33961 tttcctactt ggcttattat atcgctatca atcgcttgca accagccaag gctacaggct
    34021 tgaacgtgag ctatgtagta tggacggtct tgtttgcagt tgttttcttg ggtgcaccgc
    34081 tagatatgct gaccattatg acgtcacttg tcgtcattgc tggagtttat attattatta
    34141 aagaataaag gagattcgtg tgaaagccat catcttagca gcgggattgg gaactcgctt
    34201 gcgtcctatg actgaaaata cccctaaagc cttggttcag gttaatcaaa aacctttgat
    34261 tgagtaccaa attgagtttc tcaaagaaaa aggaatcaat gacatcatca tcattgttgg
    34321 ttatcttaaa gaacaattcg attacttgaa agagaaatac ggtgttcgtc tcgttttcaa
    34381 tgataaatac gctgactaca ataactttta ctctctctat cttgtaaaag aagaattagc
    34441 caatagttat gttatcgatg ccgataacta tctctttaaa aatatgttcc gcaatgattt
    34501 gacacgttct acttatttta gtgtctatcg tgaagattgt accaacgaat ggttcttggt
    34561 ctatggagat gactacaagg ttcaaaacat tattgttgat agcaaggcag gtcgcatcct
    34621 tagtggtgta tccttctggg atgctccaac agcagaaaaa attgttagct ttatcgataa
    34681 ggcttatgca agcggcgaat ttgttgatct ctattgggac aatatggtta aggataacat
    34741 caaagagcta gatgtctatg ttgaagaatt agaaggcaat agcatttatg agattgatag
    34801 tgtccaagac tatcataaat tagaagaaat tcttaaaaac gaaaattaaa agcttccaac
    34861 atctgacaaa atagtcggat gtttttttga ttttttacga acttttacga atagatagat
    34921 gagtagaaaa agaaatggag ttatttatga aaatcacaaa ctatgaaatc tataagttaa
    34981 aaaaatcagg tttgaccaat caacagattt tgaaagttct agaatacggt gaaaatgttg
    35041 atcaggagct tttgttgggt gatattgcag atatatcagg ttgccgtaat ccagccgttt
    35101 ttatggaacg ttattttcag atagacgatg cgcatttgtc gaaagagttt caaaaatttc
    35161 catctttctc tattttagat gactgttatc cttgggattt gagtgaaata tatgatgcgc
    35221 ctgtactttt attttacaag ggaaatcttg acctcctgaa attcccgaag gtagcggtcg
    35281 tgggcagtcg tgcttgtagc aaacagggag ctaaatcagt tgaaaaagtc attcaaggct
    35341 tggaaaatga actggttatt gtcagtggtc tggccaaggg cattgacaca gcagctcata
    35401 tggcagctct tcagaatggc ggaaaaacca ttgcagtgat tggaacagga ctggatgtgt
    35461 tttatcctaa agccaataaa cgcttgcaag actacatcgg caatgaccat ctggttctaa
    35521 gtgaatatgg acctggcgaa caacctctga aatttcattt tcctgcccgt aatcgcatca
    35581 ttgctggact ttgtcgtggt gtgattgtag cagaggctaa gatgcgttca ggtagtctca
    35641 ttacgtgtga gcgagcaatg gaagaaggac gcgatgtctt tgctattcct ggtagcattt
    35701 tagatggact atcagacggt tgccatcatt tgattcaaga aggagcaaaa ttggtcacca
    35761 gtgggcaaga tgttcttgcg gaatttgaat tttaaaaatg acctaagcta gaattctaag
    35821 aaaaaatcaa ttttaagaga aaatgaaccc aacatttcca taataaaacg catattagca
    35881 agtttttaac acttgataat atgcgttttt tctaagtgga ttagtagagt agaggatttt
    35941 tctcatataa tactcttcga aaatctcttc aaactacgtc agcttccatc tgcaacctca
    36001 aaacagtatt ttgagctgac ttcgtcagtc ttatctacaa cctcaaagca gtgctttgag
    36061 caacctgtgg ctagcttcct agtttgcgct ttgattttca ttgagtataa gggaaagtat
    36121 agtgaattga aataagatgt gaacaactct atcaggaaag tcaaattaat ttatagaaat
    36181 attttagcag ccaaggtgca ctgttataga ttcaatacac tataatttag tgtaattgag
    36241 aaaggagaaa tgattgtgat tgatgttggc taggttatgt tcaatgattc ctaccgtctc
    36301 aaatcttgtc agtaaggaaa aataaattct tcaaaagtag agattacaag gcttgtttaa
    36361 gaaagaattc aaagaccttg acaaataaaa ataaaatggt tattataaaa aatggtctga
    36421 aatagatgat gatacttttc gaaaatcttt ttacgtcagc tcagctttgc cttgctgtgt
    36481 tttgagcaag ctacggttag cttccgagtt tgattttcat ttactagaaa tgaaactgat
    36541 gagagatatc agtagacatt tgagtcagga tattatggaa aatgataaaa agagctcgtg
    36601 agattggcat atcagactac taaagtattg agtttgttag gattttagcg actagttagc
    36661 tgggaaagga agatatttgt gacaaataat aaactgtatt cgttgataga atttagaaat
    36721 aaaatatatg aagaattaga actttccaga agtgatttag cgattttact atgtgccatg
    36781 cttatcgcct ctatcggatt aaatatggat tcgactcccg tgattattgg agccatgtta
    36841 atctctcctt tgatgacacc tattctggga gtggggctct ctctagctat atttgatttt
    36901 aaattgttaa gaaaatcttt taaaatatta gctattcaaa ttcttgccag tttaatagct
    36961 tcaacacttt atttttatct ttctcccatt tcgtatgcta gttcggaaat tgttgctaga
    37021 acctctccga ctatttggga tgttctcatt gcttttgtag gagggatagc aggtattatt
    37081 ggtgctagga aaaaagagac caataatatt gttcctggtg ttgctattgc aaccgccttg
    37141 atgcctcctc tttgtacagt aggttatgct attgcttctg ctaatctaaa atttatcata
    37201 ggctcctctt acctattcct catcaattgt agctttattg tcattgcgac ttatataggt
    37261 gttaggttga tgatggttaa gaaacattat tttaaagata atgaagaaga ctctaaaatg
    37321 cgtaggattt tgcttctagt tgctgttttg ctgatgattc cgagtttcat ctctgcaacg
    37381 actttagtga gagaaacgtt gaaaaaagag tcccttaaga aatttatatc agagcagttt
    37441 caggggcata atattttgaa aaaaacctat tctaaaaaga ctcataccct aaagctaacc
    37501 atttcaggaa attatttgac agaagaagaa ctcgatatga tttcaagtaa gagaggtgac
    37561 tatggtttaa gtgatgtttc tgttcaagtt tcacaattgt ctgattcaga acaacttagt
    37621 aaggaagaac tggtggagta tttcttccag tatatcaagg ataaggaagc aaaagaaaag
    37681 gaaaaagcta ataagtttta tacagagtct gaggagcaat aatttcttga gaatagctgg
    37741 tttctctcgt gagtcttcta tgtatatcaa aggaagactg aggttttaag tataaaactt
    37801 ttcttctatt atagtagcta agtcttgaca gggttcaaaa aatggtttac actttataaa
    37861 gtttattact ttgaaaaggt gtgatactgt ggctacggca acaaaaaaga aaaaatcaac
    37921 agttaaaaaa aatctagtca tcgtggagtc gcctgctaag gccaagacga ttgaaaaata
    37981 tctaggcaga aactacaagg ttttagccag tgtcgggcat atccgtgatt tgaagaaatc
    38041 cagtatgtcc gtcgatattg aaaataatta tgaaccgcaa tatatcaata tccgaggaaa
    38101 aggccctctt atcaatgact tgaaaaaaga agctaaaaaa gctaataaag tttttctcgc
    38161 gagtgacccg gaccgtgaag gagaagcgat ttcttggcat ttggcccata ttctcaactt
    38221 ggatgaaaat gatgccaacc gtgtggtctt caatgaaatc accaaggatg cagtcaaaaa
    38281 tgcttttaaa gaacctcgta agatcgatat ggacttggtc gatgcccaac aagctcgtcg
    38341 gatcttggat cgcttggtag ggtattcgat ttcgcctatt ttgtggaaga aggtcaagaa
    38401 gggcttgtca gcaggtcgcg ttcagtccat tgcccttaaa ctcatcattg accgtgaaaa
    38461 tgaaatcaat gccttccagc cagaagaata ctggacagtt gatgctgtct ttaaaaaggg
    38521 aaccaaacaa tttcatgctt ccttctatgg agtagatggt aaaaagatga aactgaccag
    38581 caatgacgaa gtcaaggaag tcttgtctcg tctgactagt aaagactttt cagtagatca
    38641 ggtggataag aaagagcgca agcgcaatgc tcctttaccc tataccactt catctatgca
    38701 gatggatgct gccaataaaa tcaatttccg tactcgaaaa accatgatgg ttgcccaaca
    38761 gctctatgaa ggaattaata ttggttctgg tgttcaaggt ttgattacct atatgcgtac
    38821 cgattcgact cgtatcagtc ctgtagcgca aaatgaggcg gcaagcttca ttacggatcg
    38881 ttttggtagc aagtattcta agcacggtag caaggtcaaa aacgcatcag gtgctcagga
    38941 tgcccatgag gctattcgtc cgtcaagtgt ctttaataca ccagaaagca tcgctaagta
    39001 tctggacaag gatcagctca agctatatac ccttatctgg aatcgttttg tggctagcca
    39061 gatgacagcg gccgtttttg ataccatggc tgttaaattg tctcaaaatg gagttcaatt
    39121 tgctgccaat ggtagtcagg ttaagtttga tggttatctt gccatttata atgattctga
    39181 caagaataag atgttaccgg acatggttgt tggagatgtg gtcaaacagg tcaatagcaa
    39241 accagagcaa catttcaccc aaccgcctgc ccgttattct gaagcaacac tgattaaaac
    39301 cttagaggaa aatggggttg gacgtccatc aacctatgcg ccaaccattg aaaccattca
    39361 gaaacgttat tatgttcgcc tggcagccaa acgttttgaa ccgacagagt tgggagaaat
    39421 tgtcaataag ctcatcgttg aatatttccc agatatcgta aacgtgacct tcacagctga
    39481 aatggaaggt aaactggatg atgtcgaagt tggaaaagag cagtggcgac gggtcattga
    39541 tgctttttac aaaccattct ctaaagaagt tgccaaggct gaagaagaaa tggaaaaaat
    39601 ccagattaag gatgaaccag ctggatttga ctgtgaagtg tgtggcagtc caatggtcat
    39661 taaacttggt cgttttggta aattctacgc ttgtagcaat ttcccagatt gccgtcatac
    39721 ccaagcaatc gtgaaagaga ttggtgttga gtgtccaagc tgtcatcagg gacaaattat
    39781 tgagcgaaaa accaagcgta atcgcctatt ctatggttgc aatcgctatc cagaatgtga
    39841 atttacctct tgggacaagc ctgttggtcg tgactgtcca aaatgtggca acttcctcat
    39901 ggagaaaaaa gtccgtggtg gtggcaagca ggttgtttgt agcaaaggcg actacgagga
    39961 agaaaagatt aaataagagg aggggcccga aagtaaattt caggctcctt ttggttagaa
    40021 cttgacaaaa tacatcattt tatgcgaaac tagaagaaga ttattttata ctcaatgaga
    40081 atcaaagagc aaattagaaa gctagtcgca ggttgctcaa agcactactt tgaggttgaa
    40141 gatggaagct gacctggttt gaagagattt tcgaagagta ttaactagga gaagttatgc
    40201 gtattatcta tctaattatt ggttttttat cgctgacctt ggctattgtt ggggttgttt
    40261 tacccttgtt gcctacaaca cctttccttt tgttgtctat tgcttgtttc tccagaagtt
    40321 ccaagcgatt cgaagattgg ctttatcata ccaagctcta tcaagcatat gtagctgatt
    40381 ttcgtgagac caagtctatt gcgcgtgaac gaaagaaaaa aatcatcgtc tctatctacg
    40441 tcttgatggg aatttctatt tattttgcac ctcttttacc agtcaaaatc ggtctgggtg
    40501 ctttgaccat ctttattact tattatctct tcaaggtcat tccagacaaa gaatagttaa
    40561 aacagtagtt atttgccttg ataaaattga aagcatattc ataacaatat gatataataa
    40621 aattgaagta atattcaagg agaatcaaat gatttacgaa ttttgtgctg aaaatgtgac
    40681 tttacttgaa aaagcgatgc aggctggagc tcgtcggatt gaactctgtg ataatctagc
    40741 agttggtggg acaacaccca gctatggagt gactaaggca gcggttgaac tggcagctaa
    40801 ctacgataca accatcatga ccatgattcg gccacgtggt ggtgactttg tctataatga
    40861 cctagaaatt gctatcatgc tagaagacat tcgtttgact gctcaggctg gaagtcaagg
    40921 ggttgtattt ggagctttaa ctgctgataa aaagttggat aagcctaatc tggaaaagtt
    40981 aattgctgca tcaaaaggaa tggaaattgt ctttcacatg gcctttgatg aactaagtga
    41041 tgaagatcaa ccggaagcta ttgactggct cagtcaagcc ggtgtcactc gtatcctaac
    41101 tcgtgctggt gtgtctggcg actccttaga aaaacgtttt gttcactatc acagaatttt
    41161 ggagtacgct aaaggtaaaa ttgaaattct accaggtggg gggattgacc ttgaaaaccg
    41221 tcaaaccttt atcgaccagg tgggggtaac acaattgcat ggtactaagg ttgtttttta
    41281 aaaaatagaa aggaactgct agctttgggt agcagttttc acttatgttt gaaattttta
    41341 aatcctatca atttaatcaa gaaaaggctc atgattatgg ttttatagaa aatagcgaag
    41401 tctggacata tagttgccag attttgcaag gtgactttgt catgactgtg tccatcactg
    41461 ctgataatgt gaactttcaa gtctttgacc aagagactgg tgacctctat cctcacgttt
    41521 atatggaaag catgagggga agttttgtcg gaaatgtccg tgaggcttgt ctggagattc
    41581 tttaccagat tcggaaggct tgttttgatg tgcaagattt tatctgtcat cagactaagc
    41641 gtatcatgac tcaagttcag gaaaagtatg gaaaccagtt ggagtatctg tgggaaaaat
    41701 cgcctgatac agctgtattg cgccatgaag gcaatcaaaa gtggtatgcc gtcttgatga
    41761 aaatctcttg gaataagctg gaaaagggca gagaaggaca agtggaagca gtcaacctca
    41821 agcatgacca agtagctaat ttgctttcac aaaaggggat ttatccagcc ttccatatga
    41881 gcaagcgcta ctggattagt gtgtcccttg atgatacttt atcagatgaa gaagtactgg
    41941 aattgataga aaaaagttgg aacttaacct ctaaaaaatg aaatatttta ataattttca
    42001 tgaactttca attagctaaa tattctttac tgaagagatt tttagaaaat ataggattta
    42061 ccacactaga ggaatatggt gccatcttca aatacctgat tgagaatgtc aagacggatc
    42121 gtcagatcat ctattcgcct cactgtcatg atgacctcgg aatggcagtg gcaaatagcc
    42181 ttgctgctgt caagaatggt gcaggacgtg ttgaagggac tatcaatggt attagggagc
    42241 gagctgaaaa tgctgctttg gaagaaattg cagtggctct caatattcgc caagattact
    42301 accaagtaga aaccagtatt gtcctaaatg agaccatcaa tacgtcagaa atggtttctc
    42361 gcttctctgg tattccagtt cctaaaaaca aagccgtcgt tggtggcaat accttctccc
    42421 acgaatctgg tattcaccaa gatggagtcc ttaaaaatcc tctcacttat gagatcatca
    42481 cacctgaatt ggttggtgtt aagattctgc ttggaaaatt atctggtcgc catgcttttg
    42541 ttgagaaact gagagaattg gccctagatt ttacagaaga ggatatcaaa ccactctttg
    42601 ctaagttcaa ggcactggtc gataagaagc aagaaatcac agatgcagat attcgagctt
    42661 tggtagctgg aaccatggtt gaaaatccag aaggcttcca ctttgatgat ttacaacttc
    42721 aaactcatgc agataatgac attgaagcgc tcgttagcct agccaatatg gatggtgaga
    42781 aagtcgaatt taatgcgaca gggcaaggtt ccgttgaagc aatctttaat gctatcgata
    42841 agttctttaa ccaatctgtt cgtttggtgt cctacactat cgatgcggta acagatggaa
    42901 tcgataccca ggatcgggtt ttggtcactg ttgaaaacag agatacagaa accatcttta
    42961 atgcagcagg gcttgatttt gatgtgttga aggcttctgc tattgtctat ataaacgcta
    43021 atacctttgt tcaaaaagag aatgcaggtg agatgggacg cagtgtttct taccacgata
    43081 tgcctagtgt gtaaaggaga aggctatggc aaagaaaata gtagctctag caggagacgg
    43141 aattggccca gaaatcatgg aggttggttt agaagttctg gaggctctag ctgaaaaaac
    43201 aggttttgac tatgagattg acagacgacc gttcggaggt gcagatattg atgcagcatg
    43261 acctccctta cctgatgaaa cccttaaggc aagtagggaa gcagatgcta tcctactagt
    43321 agctatcggt agtcctcagt atgatggagc agtggttcgc cctgaacaag gcctgatggc
    43381 tctccgtaag gaactcaatc tttacgctaa tattcgtcct gtaaaaatct ttgacagtct
    43441 caagcatttg tcactactca aactggaacg aattgctggt gtagactttg tcgtggtgcg
    43501 tgaattgaca ggcgggattt actttggaga tcatattctt gaagagcgca atgcgcgtga
    43561 tatcaacgac tatagctatg aggaagtgga gcggattatt cgcaaagcct ttgaaattgc
    43621 aagaaatcgc agaaaaatcg ttactagtat cgataagcaa aatgttctag cgacctcaaa
    43681 actctggcgg aaagtagctg aggaagtcgc acaggatttc ccagatgtaa ccttggaaca
    43741 tcagctggta gactcagctg ctatgcttat gattaccaat cctgctaagt ttgatgttat
    43801 tgtaacggag aatctttttg gagatatttt atctgatgaa tcaagcgtct tatctggtac
    43861 acttggggtt atgccatcag ccagtcattc tgaaaatgga ccaagtctct atgaacctat
    43921 tcacagttca gcacctgata ttgcaggtca aggaattgcc aatcctattt ccatgatttt
    43981 atcagtttcc atgatgttga gagatagttt cggacgttat gaggatgcag agcgtatcaa
    44041 acgtgctgtt gagacaagtc tggcggcagg aattttaacg agagatatag gaggtcaggc
    44101 ttcaacaaag gaaatgacgg aagctattat tgcaaggtta tgaagttaga cgaaaaaatt
    44161 actctagtcc ttttgatttg gaatgtcatc attttcttga tttatggtat tgacaaatct
    44221 aaggcaagga gaagagtttg gcgcatccct gagaaaatct tacttatttt agcctttact
    44281 tttggtggtt ttggtgcctg gctagcagga atcatctttc accacaagac tcgaaaatgg
    44341 tactttaaaa tagtttggtt tcttgggatg gtgaccacac tagtagcctt atattttatt
    44401 tggaggtaat ggatggcagg gtcttcgagg gaatacgctg cttgggctct agcggactat
    44461 ggttttaagg tcgtgattgc aggatctttc ggtgacattc attacaataa tgaactcaat
    44521 aatggcatgt tgccaatcgt tcagcctaga gaggttagag agaaactagc ccagctaaaa
    44581 ccaaccgacc aggtaactgt ggacttggaa caacaaaaaa tcatctcacc agttgaagaa
    44641 ttcaccttcg agatagatag cgagtggaaa cataaactcc taaatagttt ggatgatatc
    44701 ggtattacct tgcagtatga agagttgatt gctgcttatg aaaaacaacg accagcctac
    44761 tggcaggatt agaaaaaata gaaaaggaga tatagtaaac tgaaataaga tgtaaacaaa
    44821 tgaattggag cttaacatcc atttccagca attttttaga aactacagtg gactattctg
    44881 gattcaacac attataaaat tatgacaaaa cacattcaca agaaggctac gacattttaa
    44941 aaggtgaggg cggatgtatc gtttgcccta ctaaagttgg ttacattatc atgaccagtg
    45001 acaaggcagg acttgagcgt aagttcgcag ccaaagaacg taagcgtaac aaaccaggtg
    45061 ttgttctctg cggtagcatg gatgaacttt gcgctttagc gcaactcaac ccagaaattg
    45121 aagcattcta ctaaaaacat tgggatgaag atattcttct tggttgtatc cttccttgga
    45181 aaccagaagc ctttgaaaaa ctcaaagcat acggggatgg ccgtgaagaa cttatgactg
    45241 atgtacgtgg tactagctgt tttgttatca agtttggaaa agcaggtgaa caattggctg
    45301 ccaagctttg ggaagaaggt aaaatggtct acgcctcatc tgcttcaatg acaaaacgat
    45361 tgaaactcgc tatgagcaag gtgtaatggt gtctatggtc gataaggacg gcaaactcat
    45421 cccagaacaa ggaggagcac gttcaacttc accagctcca gttgtgatcc gtaaagggct
    45481 tgacattgat atagtaaaat gaagtaagag caggacaaat taatcaggac agtcaaatcg
    45541 atttctaaca atgttttaga agtagaggtg tactattcta gtttcaatcc actataaaat
    45601 catgatgcac ctgtcagata cttttaactc atgggactac cgtcaggttg agtattatta
    45661 ggatagagaa gaagtctagt gttaaggaca ttacagctca taatactagg cttttttata
    45721 gaaattcttt tctttttcta taggatatgg tattctatgt agaaaatata tgttaataag
    45781 taatgccaat atttaaacat cattagtaaa aggagttaga ttgatgaata aaagaaaagt
    45841 tagtttagaa gatttttata aatggtatag tctaaataaa gaagagttat taaataaggc
    45901 aactgttggt gaaaagttta atgataaatt aaaagaagag tttctccagg aatggccttt
    45961 ggataggatt ttaacaatgt caatcgatga atatgtaata ggaaagggac agcaaaataa
    46021 gtctttatgc tacgctcttg agaagggaaa atacaaaaat ctatttcttg gaatttctgg
    46081 tggctcagct tcaaaatttg gtatttattg gaataaaaaa acaaacaaat ataaagatca
    46141 agctaataat gagatttcag agttggatca gcgattttca aaattaaaat cagatttgta
    46201 tgaaattatc aaagaaggta ttcgttttaa ctttgaaaat cctatttttg atatgaaaag
    46261 atcaacaaat gaatttattg gtcgttctgc tatggtgaca aaattacttt gtatctatac
    46321 tgagggagat cctttctttg gtgtaaatat taatagtcag aaagaatttt ggaaccactt
    46381 tgtttctcag acaaatcaag gtggacctta tctgcaaaat cataaaataa ttgaactgat
    46441 gtccaaaact tatcctgagt tggagccatc gaaattagga actatgcttt ttgagtattc
    46501 taagcttttt atggaaaata aggaagacaa tagtacaatg gattcatcaa acaattttcg
    46561 tcatcaatta actcaatctc tattaaagtc tccaaacctt atccttcgtg gtgctcctgg
    46621 cacaggaaag acttatcttg ctaaagaaat tgccaaagaa ttaacggatg gcaacgaaga
    46681 tcaaatcgga tttgtacaat ttcacccatc atatgattat acggattttg tagaaggttt
    46741 aagaccagta tcaaatgggg atggagctat tgagtttagg ctacaggacg gtatttttaa
    46801 agatttttgt cagaaagcaa aagaaaccca attgattgga ggacaagata attttgatga
    46861 ggcttgggat tcttacttag aatatataaa tgttgctgaa gaaaaagaat atataacaaa
    46921 aacatcttac ttatctgtta atagtagaca aaatttgtca gtaaattatg atagtggtgt
    46981 tccaggatgg tcactaccta g
//
LOCUS       DAVAZV010000010        45891 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVAZV010000010 DAVAZV010000000
VERSION     DAVAZV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45891
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.010"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1194
                     /locus_tag="VQT46_000543"
     CDS             <1..1194
                     /locus_tag="VQT46_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2370625.1"
                     /translation="STSASESASTSASASASTSASASASTSASASASTSASESASTSA
                     STSASASASTSASASASTSASTSTSTSASTSASTSASTSASTSASTSASESASTSAST
                     SASTSASASASISASESASTSASASASTSASASASTSASESASTSASASASTSTSASE
                     SASTSASASASTSASASASTSASASASTSASESASTSTSASESASTSASASASTSASA
                     SASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASASAST
                     SVSNSANHSNSQVGNASGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRK
                     RDEEE"
     gene            1255..3340
                     /locus_tag="VQT46_000544"
                     /pseudo
     CDS             1255..3340
                     /locus_tag="VQT46_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000341103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
     gene            3337..4215
                     /locus_tag="VQT46_000545"
     CDS             3337..4215
                     /locus_tag="VQT46_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide biosynthesis protein"
                     /protein_id="HET2370626.1"
                     /translation="MKKNHLVGDALILTVSDQIEELDYLLESLPNICFYIAAPVQFSE
                     KIRSLETNYNVRLRTITNEEQLNFLVDTCDFLLDINHFQEVDAIVSKFVQAGKSVFAF
                     DNTVHGNQGQEVFLSSTPDKLVSRVRDYLNEVRVGTNHQEKIIQDGTWNVFKIDDKAH
                     FIVGANVICRNFENFHVSSGKLILHDGVFINNSCSFNCMERIEIGAGTMMGEGVRFYD
                     HDHIYTAEKIEKWQWTTAPIRVGRDCWIGSNVTILKGVTIGDNTIIGAGCLIRNDIPS
                     NSVVYNNGNLVVKRRD"
     gene            4255..5130
                     /locus_tag="VQT46_000546"
     CDS             4255..5130
                     /locus_tag="VQT46_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2370627.1"
                     /translation="MENELISIVVPIYNVENYLRQCLDSIQKQTYPNFECIMVNDGSP
                     DHSSKICEEFVEKDSRFKYFEKANGGLSSARNLGIECSGGAYITFVDSDDWLEHDALD
                     RLYGALKKENADISIGRYNSYDETRYVYMTYVTDPDDSLEVIEGKAIMDREGVEEVRN
                     GNWTVAVLKLFKRELLQDLPFPIGKIAEDTYWTWKVLLRASRIVYLNRCVYWYRVGLS
                     DTLSNTWSEKRMYDEIGAREEKIAILASSDYDLTNHILIYKNRLQRVIAKLEEQNMQF
                     TEIYRRMMEKLSLLP"
     gene            5159..6169
                     /locus_tag="VQT46_000547"
     CDS             5159..6169
                     /locus_tag="VQT46_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET2370628.1"
                     /translation="MKLHLTNLYGMAGDSTVILAQNAVQKIASQLGFREVGIYFYNIA
                     SDSPSEMNKRLDGIMASISIGDILVFQSPTWNGFEFDRLLFDKLKDMQVKIICFIHDV
                     VPLMFDSNYYLMKDYMYMYNLSDVLIVPSERMKTRLMEEGLTTKKILVQGMWDHPHDL
                     SLYTPAFKKELFFAGSLERFPDLQNWSQDTPLRVFSNKGEASSSARNLSIEGWKKDEE
                     LLLELSKGGFGLVWGTYQNDGESNQYYTLNISHKVSTYLTAGIPVIVPSSLSTAKFIV
                     DQGLGFVANSLEEVHAIVDKMNLQEYQEMTNRIKTFSYLLKEGYFTKKLLVDAIYHLG
                     VE"
     gene            6179..8623
                     /locus_tag="VQT46_000548"
     CDS             6179..8623
                     /locus_tag="VQT46_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_1767 family glycosyltransferase"
                     /protein_id="HET2370629.1"
                     /translation="MIKTIVLAGDRNYIRQLETTIKSILYHNRDVKIYILNQDIMPDW
                     FRKPRKIARMLGSEIIDVKLPEQTVFQDWEKQDHISSITYTRYFIADYIQEDKVLYLD
                     SDLIVNTSLEKLFSICLEEKSLAAVKDTDGITFNAGVLLINNKKWRQEKLKERLIEQS
                     IVTMKEVEEGRFEHFNGDQTIFNQVLQDDWLELDKEFNLQVGHDVTAFYNKWENYFNE
                     LVPPSIIHFVSYRKPWTTLIANRYRDLWWEFHDLEWTKILQHHIGEFELTSSLDKEFS
                     CLTLTNSQDLEGIEELVTALPDVVFHIAAWTDMGDKLIKLAVYDNVRLHPQIVPPVLD
                     KLKKSTNLYLDINHGSADENFLKSLQEQEKTLLAFQSTQHGELGQIVFENGKVSFMID
                     TIKDFKKNGHLTCFRQLPSLTCLTFTASQDIEQLDYLAGQLPNVVFQVAAWTAMGPKL
                     YDLSNRYPNIQLYPAISRDKLDELKEKMDAYLDINLLTSTSDIVAEMAHLSKPILAFY
                     KSQNGNNGQRLYSSEHPERMLADLQKLITKDMLEKPLDIIQVKGIDETLDYIIEHNSS
                     LVRFGDGEINMLAGHSIPYQDYDEELVSIMRDIIGQESREDLVVCLPDAFTDRFRFTS
                     WAIPFWKDHMDHYMDFYRELCSDSWYGSTFVSRPYIDFEDKSQAKAQFEKLKSIWENR
                     DLLIVEGATSRSGVGNDLFDEANSIKRIICPSHSAFSRVHEIEQEIEKYAGGRLILCM
                     LGPTAKVLSYNLCQMGYQVLDVGHIDSEYEWMKMGAKTKVKFSHKHTAEYNFDQDIEF
                     IDDETYNSQIVARILN"
     gene            8654..9874
                     /locus_tag="VQT46_000549"
     CDS             8654..9874
                     /locus_tag="VQT46_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 8"
                     /protein_id="HET2370630.1"
                     /translation="MRNTKRAVAFAGDYAYIRQIETAMKSLCRHNSHLKIYLLNQDIP
                     QEWFSQIRIYLQEMGGDLIDCKLIGSQFQMNWSNKLPHINHMTFARYFIPDFVTEDKV
                     LYLDSDLIVTGDLTDLFELDLGENYLAAARSCFGAGVGFNAGVLLINNKKWGSETIRQ
                     KLIDLTEKEHENVEEGDQSILNMLFKDQYSSLEDQYNFQIGYDYGAAAFKHQFIFDIP
                     LEPLPLILHYISQDKPWNQFSVGRLREVWWEYSLMDWSVILNEWFSKSVKYPSKSQIF
                     KLQCVNLTNSWCVEKIDYLAEQLPEVHFHIVAYTNMANELLALTRFPNVTVYPNSLPM
                     LLEQIVIASDLYLDLNHDRKLEDAYEFVLKYKKPMIAFDNTCSENLSEISYEGIYPSS
                     IPKKMVAAIRSYMR"
     gene            9883..11079
                     /locus_tag="VQT46_000550"
     CDS             9883..11079
                     /locus_tag="VQT46_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HET2370631.1"
                     /translation="MRKSIVLAADNAYLIPLETTIKSVLYHNRDVDFYILNSDIAPEW
                     FKLLGRKMEVVNSTIRSVHIDKELFESYKTGPHINYASYFRFFATEVVESDRVLYLDS
                     DIIVTGELATLFEIDLKGYSIGAVDDVYAYEGRKSGFNAGMLLMDVAKWKEHSIVNSL
                     LELAAEQNQVVHLGDQSILNIYFEDNWLALDKTYNYMVGVDIYHLAQECERLDDNPPT
                     IVHYASHDKPWNTYSISRLRELWWVYRDLDWSEIAFQRSDLNYFERSNQSKKQVMLVT
                     WSADIKHLEYLVQRLPDWHFHLAAPCDCSEELTSLSQYTNVTVYQNVLHSRIDWLLDD
                     SIVYLDINTGGEVFNVVTRAQESGKKIFAFDITRKSMDDGLYDGIFSVERPDDLVDRM
                     KNIEIE"
     gene            11079..11321
                     /locus_tag="VQT46_000551"
     CDS             11079..11321
                     /locus_tag="VQT46_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2370632.1"
                     /translation="MSELISVVVPIYNTGKYLVECVEHILKQTYQNIEIILVDDGSTD
                     NSGEICDAFMMQDNRVRVLHQENKGGQHKLKIWGLV"
     gene            11306..11983
                     /locus_tag="VQT46_000552"
     CDS             11306..11983
                     /locus_tag="VQT46_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET2370633.1"
                     /translation="MGISVAKGEYITIVDSDDIVKENMIETLYQQVQEKDADVVIGNY
                     YNYDESDGNFYFYVTGQDFCVEELAIQEIMNRQAGDWKFNSSAFILPTFKLIKKELFN
                     EVHFSNGRRFDDEATMHRFYLLASKIVFINDNLYLYRRRSGSIMRTEFDLSWARDIVE
                     VFSKKISDCVLAGLDVSVLRIRFVNLLKDYKQTLEYHQLTDTEEYKDICFRLKLFFDA
                     EQRNGKS"
     gene            12040..13257
                     /gene="secY2"
                     /locus_tag="VQT46_000553"
     CDS             12040..13257
                     /gene="secY2"
                     /locus_tag="VQT46_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HET2370634.1"
                     /translation="MTKIYSSIAVKKGLFTLFLLFIYVLGSRITLPFVDLNTKDFLGG
                     STAYLAFSAALTGGNLRSLSIFSVGLSPWMSAMILWQMFSFSKRLGLTSTSIEIQDRR
                     KMYLTLMIAVIQSLAVSLRLPVQSSYSAILVVLMNTILLIAGTFFLVWLSDLNASMGI
                     GGSIVILLSSMVLNIPQDVLETFQTVHIPTGIIVLLALLTLVFSYLLALMYRARYLVP
                     VNKIGLHNRFKRYFYLEIMLNPAGGMPYMYVMSFLSVPAYLFILLGFIFPNHSGLAAL
                     SKEFMIGKPLWVYVYISVLFLFSIIFAFVTMNGEEIADRMKKSGEYIYGIYPGADTSR
                     FINRLVLRFSVIGGLFNVVMAGGPMLFVLFDEKLLRLAMIPGLFMMFGGMIFTIRDEV
                     KALRLNETYKPLI"
     gene            13267..14847
                     /gene="asp1"
                     /locus_tag="VQT46_000554"
     CDS             13267..14847
                     /gene="asp1"
                     /locus_tag="VQT46_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HET2370635.1"
                     /translation="MYYFIPAWYGSERTWHADITPWYFSHFRLEFDDTFHQIRLFQEQ
                     DIDSRLLVLAYQPHLRYFLYRHGVLETDTYSVFDVMQDFHNLHTQVLSIRDIEWDDDC
                     EFIYSPFTIIVQKNGKKFAKVEHGVEGFISDIQYFEPNGQIHMHHIMDDRGFISSIIF
                     FEDGQAAYQEYLNPKGVWQFRERLKEGGQVEVNPILGYRFKMLTYQNMGDLVAEFFEN
                     YLQTYVKDQDIFMLPSHSHHDQLVLDRLPSTNPKLLSLFIGRNPQDTFRDLDVTFEKS
                     DLILVDREDSLRLLQELYPERMHQCYHLSSFDTRLRLGRSQTKKESIIYFQLDFEQGI
                     DNQALLQVLSFVAENKDTEVIFGAFAASQEQMNEVEGIVESFIQENIQSENLGKAIDY
                     GDAENPLEENQHQDLRLQFVNLNDELDLIKTLEFVRLIVDLNRHPHLYTQIAGISAGI
                     PQINLVETVYVEHLKNGYLLTDVTEFSKAAHYYTDRLKEWNESLIYSIDKIKEHTGQQ
                     FLGKLEKWIEEVKNVKGT"
     gene            14831..16366
                     /gene="asp2"
                     /locus_tag="VQT46_000555"
     CDS             14831..16366
                     /gene="asp2"
                     /locus_tag="VQT46_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HET2370636.1"
                     /translation="MSKELNILQIGLANWENHYDIPENMSWYYFYPNSSKTLREIIEK
                     EDINRFHAVLIEDGQYSRDLFSYVKYFEPYTLFYNQNLQINDREVVDFLKKRCAQAID
                     FLSPQQLINDLSKSLFGGGYGDKLFPPTIQVNPNFTGAISYQGLDYVSLEGEFGQDFA
                     QLAYWAYNIMVQKTLPIELWLEYEKEGNCDFRLVIRKMWSGSVDDFFEEVIVSEKDLE
                     QALFMDSRDGDYFLSISVEARGRGTIKLGNLHQRWSRKQFGKFVLGGNILHDSKRDEI
                     NYFFHPGDFKPPLTVYFAGYRPAEGFEGYFMMKTLGCPFILFSDPRLEGGAFYLGTDE
                     LEGKVKDTITHYLDYLGFDHKDLILSGLSMGTFPALYYGASFEPHAIIVGKPLANLGT
                     IASRGRLDAPGVSNLAFDCLIHHTGGTSSQDMTELDQRFWKIFKQANFSKTTFGLSYM
                     KDEEMDPQAYEQLVSYLCNTGAKILSKGTAGRHNDDTDTNISWFLHFYRMVLETGFGR
                     EKR"
     gene            16363..16803
                     /gene="asp3"
                     /locus_tag="VQT46_000556"
     CDS             16363..16803
                     /gene="asp3"
                     /locus_tag="VQT46_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HET2370637.1"
                     /translation="MIITQRQSIYWGEVGGTYMYGTTVSYYLDKSVRLYNPLLPSGEI
                     LKTWFSSVNYQAARTQPQLPLLKRKQEYQLSLVFDCQPENGVYTKITFFDRYGDILEK
                     KVEKAKDFIFTYPEDSYTYQVSLLSAGFESLTFYHFSIKEIRSV"
     gene            16796..19168
                     /gene="secA2"
                     /locus_tag="VQT46_000557"
     CDS             16796..19168
                     /gene="secA2"
                     /locus_tag="VQT46_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HET2370638.1"
                     /translation="MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFR
                     QRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQVMGAIVMHYGNVAEMNTGEGKT
                     LTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
                     AEEKKLIYASDIIYTTNSSLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQ
                     TPLIIAGSPRVQSNYYAIIDTLVTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGID
                     NLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGTGRLMEMTKLQGGLH
                     QAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRI
                     PTNRPRQRIDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLF
                     REGIAHNVLNANNAAREAQIISESGQMGAVTVATSMAGRGTDIKLGKGVAELGGLIVI
                     GTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKDYQVQDM
                     TQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGS
                     RDLEDVVVDIIERYTEEVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRS
                     FMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDNWVEQVDYLQQLSMAIGGQSA
                     SQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP"
     gene            19180..20691
                     /gene="gtfA"
                     /locus_tag="VQT46_000558"
     CDS             19180..20691
                     /gene="gtfA"
                     /locus_tag="VQT46_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HET2370639.1"
                     /translation="MTIYNINLGIGWASSGVEYAQAYRAGVFRKLNLSSKFIFTDMIL
                     ADNIQHLTANIGFDDNQVIWLYNHFTDIKIAPTSVTVDDVLAYFGGEESHREKNGKVL
                     RVFFFDQDKFVTCYLVDENKDLVQHAEYVFKGNLIRKDYFSYTRYCSEYFAPKDNVAV
                     LYQRTFYNEDGTPVYDILMNQGKEEVYHFKDKIFYGKQAFVRAFMKSLNLNKSDLVIL
                     DRETGIGQVVFEEAQTAHLAVVVHAEHYSENATNEDYILWNNYYDYQFTNADKVDFFI
                     VSTDRQNEVLQEQFAKYTQHQPKIVTIPVGSIDSLTDSSQGRKPFSLITASRLAKEKH
                     IDWLVKAVIEAHKELPELTFDIYGSGGEDSLLREIIANHQAEDYIQLKGHAELSQIYS
                     QYEVYLTASTSEGFGLTLMEAIGSGLPLIGFDVPYGNQTFIEDGQNGYLIPSSSDHVE
                     DQIKQAYAAKICQLYQENRLEAMRAYSYQIAEGFLTKEILEKWKKTVEEVLHD"
     gene            20684..22021
                     /gene="gtfB"
                     /locus_tag="VQT46_000559"
     CDS             20684..22021
                     /gene="gtfB"
                     /locus_tag="VQT46_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HET2370640.1"
                     /translation="MIELYDSYSQESRDLHESLVATGLSQLGVVIDADGFLPDGLLSP
                     FTYYLGYEDGKPLYFNQVPVSDFWEILGDNQSACIEDVTQERAVIHYVDGMQARLVKQ
                     VDWKDLEGRVRQVDHYNRFGACFAKTTYSADSEPIMTVYQDVNGQQVLLENHVTGDIL
                     LTLPGQSMRYFANKVEFITFFLQDLEIDTSQLIFNTLATPFLVSFHHPDKSGSDVLVW
                     QEPLYDAIPGNMQLILESDNVRTKKIIIPNKATYERALELTDEKYHDQFVHLGYHYQF
                     KRDNFLRRDALILTNSDQIEQVEAIVEALPDVTFRIAAVTEMSSKLLDMLRYPNVVLY
                     QNASPQKIQELYQLSDIYLDINHSNELLQAVRQAFEHNLLILGFNQTVHNRLYIAPEH
                     LFESSEVAALVETIKLALSDVDQMRQALGKQGQHANYVDLVRYQEIMQTVLGG"
     gene            22023..22202
                     /gene="asp4"
                     /locus_tag="VQT46_000560"
     CDS             22023..22202
                     /gene="asp4"
                     /locus_tag="VQT46_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory system protein Asp4"
                     /protein_id="HET2370641.1"
                     /translation="MSEEDLFYKDVEGRMEELKQKPIKKEKETRGEKISKTFSLLLGL
                     MILIGLLFTLLGILR"
     gene            22207..22431
                     /locus_tag="VQT46_000561"
     CDS             22207..22431
                     /locus_tag="VQT46_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory secretory protein Asp5"
                     /protein_id="HET2370642.1"
                     /translation="MIEMLIVLAIILSLALIVLVTIQPRQNQLFSMDATSNIGKPSYW
                     QSNTLVKVLTLLVSLALFVLLLTFMVITYK"
     gene            22486..22566
                     /locus_tag="VQT46_000562"
                     /pseudo
     CDS             22486..22566
                     /locus_tag="VQT46_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(22802..23755)
                     /locus_tag="VQT46_000563"
     CDS             complement(22802..23755)
                     /locus_tag="VQT46_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2370643.1"
                     /translation="MSISQRTTKLILATCLACLFAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(23823..25032)
                     /gene="sstT"
                     /locus_tag="VQT46_000564"
                     /pseudo
     CDS             complement(23823..25032)
                     /gene="sstT"
                     /locus_tag="VQT46_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            25171..25731
                     /locus_tag="VQT46_000565"
     CDS             25171..25731
                     /locus_tag="VQT46_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET2370644.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            25788..26696
                     /locus_tag="VQT46_000566"
     CDS             25788..26696
                     /locus_tag="VQT46_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2370645.1"
                     /translation="MVLEKQLGHGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            26648..27238
                     /locus_tag="VQT46_000567"
     CDS             26648..27238
                     /locus_tag="VQT46_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET2370646.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            27241..28347
                     /gene="yqeH"
                     /locus_tag="VQT46_000568"
     CDS             27241..28347
                     /gene="yqeH"
                     /locus_tag="VQT46_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET2370647.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGTAKVAVWAPEGVAVATRKAII"
     gene            28561..28872
                     /gene="yhbY"
                     /locus_tag="VQT46_000569"
     CDS             28561..28872
                     /gene="yhbY"
                     /locus_tag="VQT46_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET2370648.1"
                     /translation="MSLASKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            28924..29553
                     /locus_tag="VQT46_000570"
     CDS             28924..29553
                     /locus_tag="VQT46_000570"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET2370649.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFLAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            29553..30146
                     /gene="yqeK"
                     /locus_tag="VQT46_000571"
     CDS             29553..30146
                     /gene="yqeK"
                     /locus_tag="VQT46_000571"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET2370650.1"
                     /translation="MSYQDYINCSREALLEKMAEFLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSNQEFLALIDRYQLDPDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIANLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            30147..30647
                     /locus_tag="VQT46_000572"
     CDS             30147..30647
                     /locus_tag="VQT46_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2370651.1"
                     /translation="MKTAFIIIDVQNILVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            30660..31013
                     /gene="rsfS"
                     /locus_tag="VQT46_000573"
     CDS             30660..31013
                     /gene="rsfS"
                     /locus_tag="VQT46_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET2370652.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            31333..32073
                     /locus_tag="VQT46_000574"
     CDS             31333..32073
                     /locus_tag="VQT46_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2370653.1"
                     /translation="MATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLELA
                     CGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGKYD
                     FVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHENA
                     EDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQAG
                     FKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            32083..33180
                     /locus_tag="VQT46_000575"
     CDS             32083..33180
                     /locus_tag="VQT46_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET2370654.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKVRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKADQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            33418..33672
                     /locus_tag="VQT46_000576"
     CDS             33418..33672
                     /locus_tag="VQT46_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HET2370655.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMAQVRAGSTQVHVIEE"
     gene            33676..33930
                     /locus_tag="VQT46_000577"
                     /pseudo
     CDS             33676..33930
                     /locus_tag="VQT46_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152757.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            34121..35734
                     /locus_tag="VQT46_000578"
     CDS             34121..35734
                     /locus_tag="VQT46_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET2370656.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            35864..36490
                     /gene="gmk"
                     /locus_tag="VQT46_000579"
     CDS             35864..36490
                     /gene="gmk"
                     /locus_tag="VQT46_000579"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET2370657.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            36515..36829
                     /locus_tag="VQT46_000580"
     CDS             36515..36829
                     /locus_tag="VQT46_000580"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET2370658.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            36895..39291
                     /locus_tag="VQT46_000581"
     CDS             36895..39291
                     /locus_tag="VQT46_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET2370659.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLKSQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGTVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSRSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            39304..40239
                     /locus_tag="VQT46_000582"
     CDS             39304..40239
                     /locus_tag="VQT46_000582"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET2370660.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            40232..41545
                     /gene="rsmB"
                     /locus_tag="VQT46_000583"
     CDS             40232..41545
                     /gene="rsmB"
                     /locus_tag="VQT46_000583"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET2370661.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIASIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            41560..42300
                     /locus_tag="VQT46_000584"
     CDS             41560..42300
                     /locus_tag="VQT46_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET2370662.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVFMNEEDAE"
     gene            42297..44276
                     /gene="pknB"
                     /locus_tag="VQT46_000585"
     CDS             42297..44276
                     /gene="pknB"
                     /locus_tag="VQT46_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET2370663.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            44391..45149
                     /locus_tag="VQT46_000586"
     CDS             44391..45149
                     /locus_tag="VQT46_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2370664.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            45151..45600
                     /locus_tag="VQT46_000587"
     CDS             45151..45600
                     /locus_tag="VQT46_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET2370665.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            45662..45891
                     /locus_tag="VQT46_000588"
                     /pseudo
     CDS             45662..45891
                     /locus_tag="VQT46_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
BASE COUNT        13981 a         8236 c        10308 g        13366 t
ORIGIN      
        1 agcacctcag cgtctgaatc ggcatcaacg agcgcctcag cttcagcaag taccagtgcg
       61 tcagcctcag cgtcaaccag tgcgtcagct tccgcatcaa cgagtgcgtc tgaatcggca
      121 tcaacctcag caagtacaag tgcatcggct tcagcaagca ccagtgcttc ggcttcagca
      181 agcacgtcag catcaacaag cacaagtaca tcggcaagca cgtcagcatc gacaagtgca
      241 agcacatcgg cgtcaacaag tgcaagtacg tcagcatctg aatcggcctc aaccagtgcg
      301 tcgacttcag caagtacaag cgcctcagcc tcagcaagta tctcagcgtc tgaatcggca
      361 tcaaccagcg cctcagcctc agcatcaaca agtgcatcag cttcagcaag cacctcagcg
      421 tctgaatcgg catcaacgag tgcctcagct tcagcaagca ccagtacctc agcttctgaa
      481 tcggcctcaa ccagtgcctc agcttcagcg tcaaccagtg cctcagcttc tgcatcaacc
      541 agcgcctcgg cctcagcaag cacctcagca tctgaatccg catcaacgag tacctcagct
      601 tctgaatcgg cctcaacaag tgcctcggcc tcagcaagca caagcgcctc agcttcagca
      661 agtaccagtg cgtcagcttc cgcatcaacg agtgcttcgg cttcagcctc aacgagtgcc
      721 tcagcttcag cgtcaaccag tgcttcagcc tcagcatcaa cgagtgcttc ggcttcagca
      781 agtaccagtg cttcggcctc agcatcgaca agtgcctcag cttcagcaag tactagcgcc
      841 tcagcctcag catcaaccag tgcctcggct tcagcaagta ctagcgcctc agcttcagcg
      901 tcaaccagtg cctcagcatc agcaagcacc tcagcgtctg aatcggcatc aaccagtgcg
      961 tctgagtcag catcaacgag tgcgtcagcc tcagcaagta catcagtttc aaattcagca
     1021 aaccattcga actcacaagt tggaaatgct tctggatcga caggtaaatc ccaaaaagaa
     1081 ttgcctaata caggtactga gtcgtcaatt ggatctgtgt tacttggagt tctagcagct
     1141 gttacaggta ttggattggt tgcgaaacgc cgtaaacgtg atgaagaaga gtaagacaac
     1201 ctgtaaagtt aggctaaact aactcgcgca cataaatcaa ggagaaaatt gctagtggat
     1261 gataaaatta cggtcattgt accagtatac aatgtagaaa actatctgag gaaatgtcta
     1321 gatagtatta tttctcaaac atataaaaat attgagattg ttgtcgttaa tgatggttct
     1381 acggatgctt caggtgaaat ttgtaaagaa ttttcagaaa tggatcaccg aattctctat
     1441 atagaacaag aaaatgctgg tatttctgcc gcacgaaaca ccggtctgaa taatatgtcc
     1501 ggaaattatg tgacctttgt ggattcagat gattggattg agttagatta tgtagaaacc
     1561 ctatataaaa aaataacaga atatcaagct gatattgcag ttgggaatta ctattctttc
     1621 aacgaaagtg aaggaatgtt ctactttcat atatcaggag actcctatta tgataaggta
     1681 tatgacaatg tttccatctt tgagaacttg ttatgaaact caagaaatga agagttttgc
     1741 tttgatatct gcttgtggta aactctataa ggcaagattg tttgagcagt tgcgctttga
     1801 catgggtaaa ttaggagaag atggttacct caatcaaaag gtatatttat tatcggaaaa
     1861 ggtaatttat ttaaataaag gtctttatgc ttatcggatt agaaaaggta gtctatcaag
     1921 agtttggaca gaaaagtgga tgcacgcctt agttgatgct atgtctgaac gtattacgct
     1981 actagctaat atgggatatc ctctagagaa acacttggca gtttatcgtc agatgttgga
     2041 agtcagtctc gccaacggtc aagctagtgg tttatctgac acagcaatat ataaagagtt
     2101 tgaaatgaaa aaaagacttt taaatcagtt aacggtacaa gaatcaagtg aaaagaaagc
     2161 cattgtccta gcagcaaact atggctatgt agaccaagtt ttaacgacaa tcaagtctat
     2221 ttgttatcat aatcgttcga ttcgttttta tctgattcat agcgattttc caaatgaatg
     2281 gattaagcaa ttaaataagc gcttagagaa gtttgactca gaaattatta attgtcgggt
     2341 aacttctgag caaatttcat gttataaaac ggatattagt tacacagttt ttttacgcta
     2401 tttcatagct gatttcgtgc aagaagataa ggccctctac ttggactgtg atttacttgt
     2461 aacgaaaaat cttgatgatt tgtttgctac agacttacaa gattatcctt tggctgctgt
     2521 tagagatttt gggggcagag cttattttgg tcaagaaatc tttaatgccg gtgttctctt
     2581 ggtaaacaat gctttttgga aaaaagagaa tatgacccaa aaattaattg atgtaaccaa
     2641 tgaatggcat gataaggtgg atcaggcaga tcagagcatc ttgaatatgc tttttgaaca
     2701 taaatggttg gaattggact ttgattataa tcatattgtc attcataaac agtttgctga
     2761 ttatcaattg cctgagggtc aggattatcc tgctattatt cactatcttt ctcatcggaa
     2821 accgtggaaa gatttggcgg cccaaaccta tcgtgaagtt tggtggtact atcatgggct
     2881 tgaatggaca gaattgggac aaaaccatca tttacatcca ttacaaagat ctcacatcta
     2941 tccaataaag gaacctttca cttgtctaat ctatactgcc tcagaccata ttgaacaaat
     3001 tgagacattg gttcaatcct tgcctgatat tcagtttaag atagcagcta gagtaatagt
     3061 tagtgatcga ttggctcaga tgacaattta tccaaacgtg actatattta acggaattca
     3121 ctatttggta gatgtcgata atgaattggt agaaaccagt caagtacttt tagatattaa
     3181 tcatggtgaa aaaacagagg aaattatcaa tcaatttgca agacttggaa aaactatttt
     3241 gtcctttgaa aataccaaaa cctatgaagc aggtcaggag gtatatgctg ttgaccaagt
     3301 tcaagcaatg attgagaaat tgagagaaat aagcaaatga agaaaaatca tttagtagga
     3361 gatgctctga ttttgactgt tagtgatcag attgaagagt tggattatct ccttgaatcc
     3421 ttgccaaata tctgttttta tattgcagca cctgttcaat tttccgagaa aatccgtagc
     3481 ttagaaacga actataatgt ccgtctccga acgattacaa atgaagaaca gctaaacttt
     3541 ctagtcgata cctgtgactt tttactagat atcaatcact ttcaagaagt agatgctatt
     3601 gtctccaagt ttgtacaggc tggaaaatct gtctttgctt ttgacaatac agtccatgga
     3661 aatcaggggc aggaagtttt tctatcaagt acaccagaca aattggtttc tagagtgaga
     3721 gactatctga atgaagtcag agtaggcacc aatcatcaag aaaaaatcat ccaagatggg
     3781 acttggaatg tctttaaaat cgatgataag gctcacttca ttgtaggagc aaatgtcatc
     3841 tgcagaaatt ttgaaaattt tcatgtctct tctggtaagt taatactgca tgatggtgtt
     3901 tttatcaaca actcttgtag ttttaactgt atggaaagaa ttgaaatcgg agctggtacc
     3961 atgatgggag agggtgttcg tttttatgat cacgaccata tttatactgc tgaaaagatt
     4021 gaaaagtggc agtggactac agcgccgatt agagttggca gagactgctg gataggaagt
     4081 aatgtcacga ttttaaaagg agtgacgatt ggggataata ccattattgg agcaggttgt
     4141 ctcatacgca atgatattcc atcaaacagt gtagtttata ataatggaaa tcttgttgta
     4201 aagagaagag attaagaggg aaatagaata aatcaagtct aggaaagtta gtatatggaa
     4261 aatgaactaa ttagtattgt agtcccaatc tacaacgttg agaattattt gcgacagtgt
     4321 ttggatagta ttcaaaaaca aacttatccg aattttgaat gtatcatggt taatgatggc
     4381 tctccagatc attcatccaa aatatgtgaa gaatttgtag agaaagattc tcgtttcaaa
     4441 tattttgaga aagcaaacgg cggtctttca tcagctcgta acctaggtat tgaatgttcg
     4501 gggggggcgt acattacttt tgtagactct gatgattggt tggaacatga tgctttagac
     4561 cgattatatg gtgctttgaa aaaggaaaac gcagatatta gtatcgggcg ttataattct
     4621 tatgatgaaa cacgctatgt gtatatgact tatgttacgg atccagatga ttctctggaa
     4681 gtgatagaag gtaaagcaat catggatagg gaaggtgtcg aagaagtcag aaatgggaac
     4741 tggactgtag ctgtcttgaa gttattcaag agagagttac tacaagattt accatttcct
     4801 ataggaaaaa ttgcagagga tacttactgg acatggaagg tacttctaag agcttcgagg
     4861 atagtctatt tgaatcgttg tgtttactgg taccgtgttg gtttatctga tactttatcg
     4921 aatacatgga gtgaaaagcg tatgtatgat gaaatcgggg ctagggaaga aaagatagct
     4981 attttagcaa gttcagacta tgacttgacc aatcatattt tgatttataa aaatagatta
     5041 caaagagtga tagcaaaatt agaagaacaa aatatgcagt tcacagagat ttatagaaga
     5101 atgatggaaa aattgtcttt acttccgtag atagtaataa aaaatgagat agcgtaatat
     5161 gaaactacat ttaacaaatt tatacggcat ggctggtgat agtacggtta tcttagctca
     5221 aaatgctgtt caaaagatag ctagtcaact gggatttaga gaggttggta tttattttta
     5281 caacattgct tcagatagtc cttctgaaat gaataagcgt ctggatggta ttatggccag
     5341 tatttctatt ggggatattt tagtctttca gtctccaacc tggaatggct ttgaatttga
     5401 tcgtctcttg tttgataagt tgaaggatat gcaggtgaaa attatttgct ttatccatga
     5461 tgttgttccc ctcatgtttg atagtaacta ttatctcatg aaagactata tgtacatgta
     5521 taatctatca gatgttttga tagtgccgtc agagagaatg aaaacacgcc tgatggaaga
     5581 aggattgacg actaagaaga ttcttgttca agggatgtgg gatcatcctc atgatttatc
     5641 cttatacacc cctgctttta aaaaagaact tttttttgct ggaagtttag agcgttttcc
     5701 agacttacaa aattggtctc aagatacgcc tttgagagta ttttcaaata aaggggaagc
     5761 tagttctagt gctagaaatc tcagcatcga aggatggaaa aaagatgagg aattgttgct
     5821 agaattatca aagggtggat ttggccttgt ctggggaact tatcaaaacg atggagaaag
     5881 caaccaatat tataccttaa atatatctca taaggtgagt acctatctga cagcgggcat
     5941 cccagtcatt gtaccaagta gcttgtcaac tgctaaattt atagtagatc aaggcttagg
     6001 ctttgtggcg aatagtctag aagaagttca tgcgatagtt gataaaatga atctacaaga
     6061 atatcaagaa atgacgaatc ggataaaaac ctttagttat ttgctaaaag aaggttattt
     6121 tactaaaaaa ttattggtag atgcaattta ccatttggga gttgaataag agaacaagat
     6181 gattaaaaca attgtattag ctggtgatcg taattacatc aggcagttag aaacaaccat
     6241 aaaatctatt ttataccaca atcgagatgt taagatttat attttaaatc aagatattat
     6301 gccagattgg tttcgcaaac cacgaaaaat agctcgcatg ttaggtagtg agattatcga
     6361 tgtgaagcta cctgaacaaa ctgtgtttca agattgggaa aagcaagatc acattagtag
     6421 cattacctat actagatatt ttattgcaga ttatatccaa gaagataagg ttttatattt
     6481 agacagtgat ttgattgtaa atacttcttt agagaaatta tttagtattt gtttagaaga
     6541 aaaatcactc gcagcagtta aagatacaga tggaattaca tttaatgcag gtgttttatt
     6601 aatcaacaat aaaaaatggc gtcaagagaa attaaaagaa cgactaattg aacagagcat
     6661 tgttacaatg aaggaagttg aagaaggccg tttcgagcat tttaatggtg atcaaacgat
     6721 ttttaatcag gtcttacaag atgattggtt agagctggat aaagaattta accttcaagt
     6781 gggtcatgat gtaactgctt tttataataa atgggaaaat tattttaatg agttagtacc
     6841 tcctagtatt attcattttg tgtcttacag aaaaccctgg accaccttga tagccaatcg
     6901 ttatcgtgat ttatggtggg aatttcatga tttggaatgg actaaaattt tacaacatca
     6961 tataggggag tttgaactga catcgtcttt agataaggaa ttttcttgtt taactttgac
     7021 aaattcccaa gatttagaag gaatagaaga gttagtcaca gctttaccag atgtggtatt
     7081 tcatattgct gcttggacgg atatgggtga taagctgata aaattagctg tgtatgataa
     7141 tgtgagattg catccacaaa ttgttcctcc tgtattagat aagctgaaaa agtcaacaaa
     7201 tctatatttg gatatcaatc atggtagtgc agatgagaac tttttaaaat ctttgcaaga
     7261 acaagaaaaa acgctactag cttttcaatc gactcagcac ggagagttag gacaaatcgt
     7321 tttcgaaaat gggaaagttt cctttatgat tgatacgatt aaagatttta agaaaaacgg
     7381 acatcttacc tgttttcgac aacttccaag tttaacttgt ttaacgttta cggcttctca
     7441 ggatatcgaa caattggatt acttggctgg acagttgcca aatgttgttt ttcaagttgc
     7501 tgcttggaca gctatggggc caaaattata tgatttgtct aatcgttatc ctaatattca
     7561 gctctatccg gcaatttcta gagataagct agacgagttg aaggagaaga tggatgctta
     7621 tttagatatc aacctactga cttcaacatc cgatatcgtt gcagaaatgg ctcatctatc
     7681 taaacctata ctagcctttt ataaatctca aaatgggaat aatggccaaa ggttgtattc
     7741 aagtgaacat cctgaacgaa tgttggctga tttgcaaaaa ttgataacta aggatatgct
     7801 agaaaaaccg cttgatataa tccaggtgaa agggatagat gaaaccttgg attatattat
     7861 tgaacacaac tcttctttag ttcgttttgg agatggggaa atcaatatgc ttgcagggca
     7921 ttcaattccc taccaggatt atgatgaaga gttggtttca atcatgaggg acattatcgg
     7981 ccaagaaagt cgagaagatt tagtagtgtg ccttcctgat gcttttacag atcgttttag
     8041 gtttacatcg tgggcgattc cattttggaa agatcacatg gatcattata tggattttta
     8101 cagagagtta tgcagtgatt catggtatgg ctcaaccttt gtatctcgcc cttatatcga
     8161 ttttgaagac aagagtcaag ctaaagctca atttgaaaaa ttgaaaagca tttgggaaaa
     8221 ccgtgactta ctgatagtcg aaggtgcgac ttctcgttca ggtgtcggaa atgatttatt
     8281 cgatgaggca aattctatta agcgaattat ctgtccttct catagtgcct tttctagagt
     8341 tcatgaaatt gaacaagaaa ttgaaaagta tgctggtggt cgcttgattt tatgtatgct
     8401 gggtcctaca gcaaaagttc tgagttataa tctatgccag atgggctatc aagttttgga
     8461 tgtaggccat attgactcag agtatgaatg gatgaaaatg ggagctaaaa ctaaggttaa
     8521 attttctcat aaacatactg cagagtataa ttttgatcaa gatattgaat ttattgatga
     8581 tgaaacctat aacagtcaga ttgttgcacg aatattaaac tagactattt aaaataaatg
     8641 ataaggattt aaaatgagaa ataccaaacg cgctgtagca tttgcaggtg attacgctta
     8701 tattcgacaa atcgaaacgg cgatgaagtc actctgtaga cacaatagtc atttgaaaat
     8761 ttatctgcta aatcaggaca ttcctcagga atggtttagt caaataagaa tatatttaca
     8821 agagatgggg ggcgacttga ttgactgcaa gttaattggc tcacagtttc aaatgaattg
     8881 gtctaataaa ttacctcata tcaatcatat gacatttgca cgctatttta ttccagattt
     8941 tgtaacagaa gataaagttc tctatctaga tagtgatttg attgtgactg gtgatttgac
     9001 cgatttgttt gaattagact taggtgaaaa ttatttggca gcagctcgtt cttgctttgg
     9061 agcaggagtc ggcttcaatg ctggtgttct cttgattaac aacaaaaaat ggggatctga
     9121 aactattcga caaaaattga ttgacttaac agaaaaagaa catgagaatg tggaagaagg
     9181 agaccagtca attttgaata tgttgtttaa agatcaatat agttcccttg aagatcaata
     9241 taattttcaa ataggatatg attatggggc ggcagccttt aaacatcaat tcatttttga
     9301 tattccgctc gaaccactgc cactaatttt acactatatt tctcaggata agccttggaa
     9361 tcaattttct gttggacgtc taagagaagt ttggtgggaa tactctttga tggattggtc
     9421 tgttatttta aatgaatggt tttcaaagag tgtgaagtat cctagtaaat cacaaatatt
     9481 taagttacaa tgtgttaatt taacgaattc ttggtgtgtc gagaaaatcg attatttggc
     9541 ggagcaattg ccagaagttc attttcatat tgttgcttat acaaatatgg caaatgaact
     9601 actagcttta acgcgttttc ctaatgttac cgtatatcca aattccttac caatgttatt
     9661 ggaacaaata gtaatagctt cagatttgta tttggatttg aatcatgatc gaaaattaga
     9721 agatgcatat gagtttgtgc ttaagtacaa aaaaccaatg atagctttcg acaatacttg
     9781 ctctgaaaat ctttctgaga tttcatatga aggtatctat ccaagctcca ttccgaaaaa
     9841 aatggttgca gcaatcagat cttacatgag gtagagaaca gtatgagaaa atcaatagta
     9901 ttagcggcag ataatgccta tcttattcct ttagagacga ctataaagtc tgtattgtat
     9961 cacaatagag atgttgattt ttatattctc aacagtgata tagctcctga atggtttaaa
    10021 ttattgggga gaaaaatgga agttgtgaat tctacaattc gcagtgtaca cattgataaa
    10081 gaactttttg aaagctataa aacaggacct catataaatt atgcttctta ctttagattt
    10141 tttgcgacag aagtggttga atctgatagg gtattgtatc tggattccga tatcattgta
    10201 actggggaac tagctacttt gtttgagata gatctcaaag gatattcaat tggtgctgtt
    10261 gatgatgtct atgcctatga aggacgaaaa tctggattta atgctggtat gttactaatg
    10321 gatgttgcaa aatggaaaga acactctatt gtcaatagtt tattggaatt agcggccgag
    10381 caaaatcaag ttgttcatct tggggatcag agtattttaa atatttattt tgaggataat
    10441 tggctagcct tagataaaac atataattat atggtgggtg ttgatattta tcaccttgct
    10501 caagaatgtg aacgtctaga tgacaatcca cctacaattg ttcactatgc tagtcatgat
    10561 aaaccttgga atacatatag tatatctaga ctacgtgaat tatggtgggt ttatagagat
    10621 ttggattggt cagagattgc ttttcaacgt tccgatttaa attattttga aagaagcaat
    10681 cagtctaaaa aacaagtgat gcttgtgaca tggagtgcag atataaaaca tttagagtat
    10741 ttagtacaac ggttacctga ttggcatttt catttggctg caccgtgtga ttgttctgag
    10801 gagctgacct ctctatcaca gtatacgaat gtaacagtat atcaaaatgt attacatagt
    10861 agaattgatt ggctattgga cgattctata gtttatttag atattaatac aggtggagag
    10921 gtttttaatg tagttacaag ggcacaagaa agtggcaaga aaatcttcgc ttttgatatc
    10981 acacgtaaaa gtatggatga tggactctat gacggtattt tttctgtgga gagaccagat
    11041 gatttagtgg atagaatgaa gaatatagag atagagtaat gagtgaatta attagtgttg
    11101 tggtaccgat atacaatacg ggaaaatatt tagtggagtg tgtcgagcat attctgaagc
    11161 aaacctatca aaatatagaa attattttag ttgatgacgg ttctacggat aattctgggg
    11221 aaatttgtga tgcttttatg atgcaagata atcgtgtgcg agtattgcat caagaaaata
    11281 agggggggca gcacaagcta aaaatatggg gattagtgta gctaagggag agtacatcac
    11341 gattgttgat tcagatgata tcgtaaaaga aaatatgatt gaaactcttt atcagcaagt
    11401 ccaagaaaag gatgcagatg ttgttatagg gaattactat aattatgacg aaagtgacgg
    11461 gaatttttat ttttatgtaa cagggcaaga tttttgcgtc gaagaattag ctatacaaga
    11521 aattatgaac cgtcaagcag gagattggaa attcaatagc tcggccttta tattgccgac
    11581 atttaagttg attaaaaaag aattattcaa tgaagttcac ttttcaaatg gtcgccgctt
    11641 tgatgatgaa gcaactatgc atcgctttta tcttttagcc tctaaaatcg tctttataaa
    11701 cgataatctc tatctgtata gaagacgttc aggaagcatc atgagaacgg aatttgatct
    11761 ttcctgggca agagatattg ttgaagtgtt ttctaagaaa atatcggatt gtgtcttggc
    11821 tggtttggat gtctccgttc tgcgtattcg atttgtcaat cttttaaaag attataagca
    11881 aactttagaa taccatcaat taacagatac tgaggaatat aaagatattt gtttcagatt
    11941 aaagttgttt tttgatgcag aacaaagaaa tggtaaaagt tgaaataaaa gaattgttat
    12001 ttaccatatc acaaacaatg aaggtgaggg gagtgtttta tgactaagat ttattcgtca
    12061 atagcagtaa aaaaaggact atttacctta tttctactgt ttatctatgt attgggaagt
    12121 cgtattactc tcccttttgt tgacctaaat actaaagatt ttttaggagg ttcaacagcc
    12181 tatctagcct tctcagccgc cctaacaggt ggaaatctaa gaagtttgtc aattttttct
    12241 gttggattgt ccccttggat gtcagctatg attttatggc agatgttttc tttttctaaa
    12301 cggttgggtt taacatctac gtctatagaa atacaagatc gccgtaaaat gtacctgacc
    12361 ttgatgatag ctgtcattca atcattggca gttagcttga gactgccagt acaatcctcc
    12421 tattctgcaa tattggttgt tctaatgaat acaatattgc tgatagcagg aacatttttt
    12481 cttgtttggt tgtcagattt aaatgcgagt atggggattg gaggttctat agtcattctc
    12541 ctatccagta tggttttaaa tattcctcag gatgttttgg aaacatttca gacagtacac
    12601 attccaacag ggattattgt gttacttgct ttattaaccc ttgtcttttc ttatttactt
    12661 gcccttatgt atcgagctcg ctatttggtt cctgttaata aaattggctt acacaatcga
    12721 tttaaacgct atttttatct cgaaatcatg ttgaatcctg caggtgggat gccttatatg
    12781 tatgtgatga gttttcttag tgtaccagct tatttgttca tcttgttggg atttattttc
    12841 cctaatcatt cagggttagc ggctttatca aaggaattta tgattggaaa gcctttgtgg
    12901 gtctatgttt atatttcggt cttattttta tttagtatca tttttgcttt tgttacgatg
    12961 aatggagaag agattgcaga ccgtatgaaa aaatctggag aatacattta tggtatttat
    13021 ccaggtgcgg atactagtcg atttattaat cgattggtcc ttcgtttctc agtcataggt
    13081 ggtctcttta atgtggttat ggcaggtggt cccatgcttt ttgttttgtt tgatgaaaag
    13141 ttattacgat tggcaatgat tccaggtttg tttatgatgt ttggaggcat gatttttacg
    13201 attagagacg aggtcaaggc tttaaggcta aatgagacct ataaaccttt gatttaggag
    13261 acttttatgt attattttat tccagcttgg tatgggtcag aaagaacatg gcatgcagat
    13321 atcactccat ggtatttttc tcattttcgt ctagagtttg atgatacctt tcaccagatc
    13381 cggctctttc aagagcaaga tatagattct cgtctattag tattagctta ccagcctcat
    13441 ctacgttatt ttttatatag acatggtgtg ttagaaacgg atacttattc cgtttttgat
    13501 gttatgcaag attttcataa tctccatacc caagttttaa gcattagaga tattgagtgg
    13561 gatgatgact gtgaatttat ttatagtccc tttacgatta tcgttcaaaa aaatgggaag
    13621 aaatttgcta aggttgaaca tggagttgaa ggcttcatca gtgatataca gtattttgaa
    13681 ccaaatggtc aaatacatat gcaccatatc atggatgatc gagggtttat atcgagtatt
    13741 attttttttg aagatgggca agcagcctat caagaatatt tgaatcctaa gggagtttgg
    13801 caatttagag agcgtttaaa agaaggagga caggtagaag tcaatccaat tttgggttat
    13861 cgctttaaaa tgcttaccta tcaaaatatg ggagatctgg tggcagaatt ttttgagaat
    13921 tatctgcaaa cgtatgtgaa ggatcaggat atttttatgc ttccttctca ttctcatcat
    13981 gaccagttgg tactagatcg tttacctagt actaatccta aactgttgag tctgttcatt
    14041 ggacgtaatc ctcaagatac ctttagggat ttagatgtaa cttttgaaaa atcggatttg
    14101 attttggtgg atagagagga tagtttacga ttgttgcagg agttgtatcc tgaacgaatg
    14161 catcaatgtt atcatttatc atcttttgac acccgattac gattgggacg aagccaaact
    14221 aagaaagaat ccatcattta ttttcaactg gattttgagc aggggattga taatcaagct
    14281 ctgcttcaag tcttgtcctt tgtcgctgaa aataaggata ctgaggtgat ttttggagcc
    14341 tttgctgcta gtcaggagca aatgaatgag gttgaaggga ttgttgagtc tttcatccaa
    14401 gaaaacattc aatccgaaaa tctgggaaag gcgattgatt atggtgatgc agaaaatccc
    14461 ctggaagaaa atcaacacca ggacttacgc ttacagtttg ttaacttgaa tgatgagtta
    14521 gatttgataa aaacactaga atttgtccgt ttgattgtgg atttaaatag acatcctcat
    14581 ctctacacac agattgctgg gattagtgca ggaattcctc aaatcaacct agttgaaacc
    14641 gtctatgtgg aacatttaaa aaatggttat ttgctgacag atgtgacaga attttctaag
    14701 gctgcacatt attacacaga taggttgaag gagtggaatg agtccttgat atattcaatt
    14761 gataagatta aggagcacac aggacaacaa tttcttggaa aattagagaa atggatagag
    14821 gaggttaaaa atgtcaaagg aacttaatat tttacagata ggacttgcca attgggaaaa
    14881 tcactatgac atacctgaaa atatgagttg gtattatttt tacccaaact catcaaaaac
    14941 ccttcgtgaa ataatcgaaa aagaggatat taaccgtttt catgcagttt taatagaaga
    15001 tggtcagtat tccagagact tattttccta tgtaaaatat tttgaacctt atactttgtt
    15061 ctataaccag aatctacaaa taaatgatag agaggttgtg gattttctaa aaaaacgatg
    15121 tgcacaagca attgattttt taagtcccca acaactaatc aatgatttaa gtaaatctct
    15181 ttttggcggt gggtatggtg ataaactctt tcctccgacg atacaagtca atccaaattt
    15241 tacaggagct atttcttatc aaggattgga ttatgtcagt ttggaaggtg agtttgggca
    15301 agattttgcc cagcttgcct attgggctta taatattatg gtgcaaaaaa cactccctat
    15361 tgagttgtgg cttgaatatg agaaggaagg caattgtgac tttcgtttag taatccgtaa
    15421 aatgtggagt gggtctgttg atgatttctt tgaagaagta atagtatctg aaaaagactt
    15481 ggagcaagca ctttttatgg atagtcgaga cggagactac tttctctcga tatctgttga
    15541 agcaagaggt cgtggaacta tcaaactagg taatcttcac caacgatgga gtcgaaaaca
    15601 atttggtaag tttgtacttg gtggaaatat cctacatgat tccaagcgtg atgaaataaa
    15661 ctatttcttc catccaggtg attttaaacc gcctttgact gtctattttg caggttatcg
    15721 acctgcagaa ggattcgagg gttactttat gatgaaaact cttggatgtc ccttcatttt
    15781 attttctgat ccacgtttag aggggggagc tttttatctc ggaacggatg agctagaggg
    15841 aaaagtaaag gatacgatca ctcactatct tgattattta ggctttgatc ataaggattt
    15901 gattttatca ggtctttcta tgggaacgtt tccggctctc tattatggtg cttcttttga
    15961 accccatgcc atcatagttg gtaagccctt ggctaattta ggaactatag ctagtcgtgg
    16021 acgtttggac gcaccgggtg tctctaactt agcttttgat tgtttaattc atcatacagg
    16081 tgggacaagt tctcaagata tgacggagtt ggatcagcgt ttttggaaaa tttttaaaca
    16141 agcaaatttt tcaaagacaa cctttggttt atcctatatg aaagatgaag aaatggatcc
    16201 acaagcctat gaacaattag tgtcttatct gtgtaataca ggtgcgaaga ttttatctaa
    16261 aggaactgct ggacgacaca atgatgatac agataccaat atttcttggt ttttgcactt
    16321 ttatagaatg gtcttagaga ctggttttgg aagggagaaa agatgattat tacacagaga
    16381 cagtctattt attggggaga agttggtggg acttatatgt atggaacaac tgtatcttat
    16441 taccttgaca aaagtgttcg tctgtataat cctctattgc catctggtga gattctaaag
    16501 acttggtttt ctagtgtcaa ttaccaggct gcacgaaccc aacctcagct tcccttatta
    16561 aaaagaaagc aggagtatca actatcactg gtttttgatt gtcagcctga aaatggagtt
    16621 tataccaaga taactttttt tgaccgctat ggtgatattt tagaaaaaaa ggtagaaaaa
    16681 gcgaaagatt tcatatttac ttatccagaa gatagttata cttatcaagt ttctctttta
    16741 agtgctggat ttgagtcctt aactttttat catttttcta tcaaggagat cagaagtgtt
    16801 tagacgttta ggtcaagatt tccagcttag gaaagtgaaa aagattttaa agcagattaa
    16861 tgccctgaaa ggcaagatgt cctctctttc ggatcaagaa ttagtagcta aaacagtaga
    16921 gtttcgtcag cgtctttccg agggagaaag tctagacgat attttggttg aagcttttgc
    16981 tgtggtgcgt gaagcagata agcggatttt agggatgttc ccctatgatg ttcaagtcat
    17041 gggagctatt gtcatgcact atggaaatgt tgctgagatg aatacggggg aaggtaagac
    17101 cttgacagct accatgcctg tctatttgaa cgctttttca ggagaaggag tgatggttgt
    17161 gactcctaat gagtatttat caaagcgtga tgccgaggaa atgggccaag tttatcgttt
    17221 tctaggattg accattggtg taccatttac ggaagatcca aagaaggaaa tgaaagctga
    17281 agaaaagaag cttatctatg cttcggatat catctacaca accaatagta gtttaggttt
    17341 tgattatcta aatgataacc tagcctcgaa tgaagaaggt aagtttttac gaccgtttaa
    17401 ctatgttatt attgatgaaa ttgatgatat cttgcttgat agtgcacaaa ctcctctgat
    17461 tattgcgggt tctcctcgtg ttcagtctaa ttactatgcg atcattgata cacttgtaac
    17521 aaccttggtc gaaggagagg attatatctt taaagaggag aaagaggagg tttggctcac
    17581 tactaagggg gccaagtctg ctgagaattt cctagggatt gataatttat acaaggaaga
    17641 gcatgcgtct tttgctcgtc atttggttta tgcgattcga gctcataagc tctttactaa
    17701 agataaggac tatatcattc gtggaaatga gatggtactg gttgataagg gaacagggcg
    17761 tctaatggaa atgactaaac ttcaaggagg tctccatcag gctattgaag ccaaggaaca
    17821 tgtcaaatta tctcctgaga cgcgggctat ggcctcgatc acctatcaga gtctttttaa
    17881 gatgtttaat aagatatctg gtatgacagg gacaggtaag gtcgcggaaa aagagtttat
    17941 tgaaacttac aatatgtctg tagtacgcat tccaaccaat cgtccgagac aacggattga
    18001 ctatccagat aatctatata tcactttacc tgaaaaagtg tatgcatcct tggagtacat
    18061 caagcaatac catgctaagg gaaatccttt actcgttttt gtaggctcag ttgaaatgtc
    18121 tcaactctat tcgtctctct tgtttcgtga agggattgcc cataatgtcc taaatgctaa
    18181 taatgcggcg cgtgaggctc agattatctc cgagtcaggt cagatggggg ctgtgacagt
    18241 ggctacctct atggcaggac gtggtacgga tatcaagctt ggtaaaggag tcgcagagct
    18301 tgggggcttg attgttattg ggactgagcg gatggaaagt cagcggatcg acctacaaat
    18361 tcgtggccgt tctggtcgtc agggagatcc tggtatgagt aaattttttg tatccttaga
    18421 ggatgatgtt atcaagaaat ttggtccatc ttgggtgcat aaaaagtaca aagactatca
    18481 ggttcaagat atgactcaac cggaagtatt gaaaggtcgt aaataccgga aactagtcga
    18541 aaaggctcag catgccagtg atagtgctgg acgttcagca cgtcgtcaga ctctggagta
    18601 tgctgaaagt atgaatatac aacgggatat agtctataaa gagagaaatc gtctaataga
    18661 tggttctcgt gacttagagg atgttgttgt ggatatcatt gagagatata cagaagaggt
    18721 agcggctgat cactatgcta gtcgtgaatt attgtttcac tttattgtga ccaatattag
    18781 ttttcatgtt aaagaggttc cagattatat agatgtaact gacaaaactg cagttcgtag
    18841 ctttatgaag caggtgattg ataaagaact ttctgaaaag aaagaattac ttaatcaaca
    18901 tgacttatat gaacagtttt tacgactttc actgcttaaa gccattgatg acaactgggt
    18961 agagcaggta gactatctac aacagctatc catggctatc ggtggtcaat ctgctagtca
    19021 gaaaaatcca atcgtagagt actatcaaga agcctacgcg ggctttgaag ctatgaaaga
    19081 acaaatccgt gcggatatgg tgcgtaatct cctgatgggg ctggttgagg tcactccaaa
    19141 aggtgaaatc gtgactcatt ttccataaga ggagaaaata tgacaattta caatataaat
    19201 ttaggaattg gttgggctag tagcggtgtt gaatacgctc aagcctatcg tgctggtgtt
    19261 tttcggaaat taaatctgtc ctctaagttt atctttacag atatgatttt agccgataat
    19321 attcagcact taacagccaa tattggtttt gatgataatc aggttatctg gctttataat
    19381 catttcacag atatcaaaat tgcacctact agcgtgacag tggatgatgt cttggcttac
    19441 tttggtggtg aagaaagtca cagagaaaaa aatggcaagg ttttacgtgt attctttttt
    19501 gaccaagata agtttgtaac ctgttatttg gttgatgaga acaaggactt ggttcaacat
    19561 gccgagtatg tttttaaggg aaacctgatt cggaaggatt acttttctta tacgcgttat
    19621 tgtagcgagt attttgctcc caaggacaat gttgcagtct tataccaacg aactttttac
    19681 aatgaagacg ggactccagt ctatgatatt ttgatgaatc aagggaagga agaagtttat
    19741 catttcaagg ataagatttt ctatggaaag caagcttttg tgcgtgcctt tatgaaatct
    19801 ttgaatttga acaagtctga tttggttatt ctggataggg agacaggtat tggacaggtt
    19861 gtgtttgagg aagcacagac agcacatcta gcggtagttg ttcatgcgga gcattatagt
    19921 gaaaatgcta caaatgagga ctatatcctt tggaataact attatgacta tcagtttacc
    19981 aatgcagata aggttgactt ctttatcgtg tctactgata gacaaaatga agttctacaa
    20041 gagcaatttg ccaaatatac tcagcatcag ccaaagattg ttaccattcc tgtaggcagt
    20101 attgattcct tgacagattc aagtcaaggg cgcaaaccat tttcattgat tacggcttca
    20161 cgtcttgcca aagaaaagca cattgattgg cttgtgaaag ctgtgattga agctcataag
    20221 gagttaccgg aactaacctt tgatatctat ggtagtggtg gagaagattc tctgcttaga
    20281 gaaattattg caaatcatca ggcagaggac tatatccaac tcaaggggca tgcggaactt
    20341 tcgcagattt atagccagta tgaggtctac ttaacggctt ctaccagcga aggatttggt
    20401 ctgaccttga tggaagctat tggttcaggt ctacctctaa ttggttttga tgtgccttat
    20461 ggtaatcaga cctttataga ggatgggcaa aatggttatt tgattccaag ttcatctgac
    20521 catgtagaag accaaatcaa gcaagcttat gccgctaaga tttgtcaatt gtatcaagaa
    20581 aatcgtttgg aagctatgcg tgcctattct tatcaaattg cagaaggctt cttgaccaaa
    20641 gaaattttag aaaagtggaa gaaaacagta gaggaggtgc tccatgattg aactttatga
    20701 tagttacagt caagaaagta gagatttaca tgaaagtcta gtcgctactg gtctttctca
    20761 acttggagtg gtcatcgatg cagatggttt tctgcctgat ggtctgcttt ctccttttac
    20821 ctattatcta ggttacgagg atggaaaacc tctctatttt aaccaagttc ccgtttcaga
    20881 tttttgggaa attttaggag ataatcagtc tgcttgtatt gaagatgtga cgcaggagag
    20941 ggctgtcatt cattatgttg atggaatgca ggctcgcttg gttaaacagg tagactggaa
    21001 agacctagaa ggtcgagtac gtcaggttga ccactacaat cgctttggtg cttgctttgc
    21061 taaaaccact tatagcgcag atagcgagcc gattatgaca gtttaccaag atgtcaatgg
    21121 ccaacaagtt ttactggaaa accatgtgac gggtgatatc ttattgactt tgcctggtca
    21181 gtccatgcgt tactttgcaa ataaagttga atttatcacc ttctttttgc aagatttgga
    21241 aatagatacc agtcagctta tctttaatac tctagcgact cctttcttgg tttccttcca
    21301 tcatccagat aaatctggct cggatgtctt ggtatggcag gaacctctct atgatgccat
    21361 tccaggtaat atgcagttga ttttggaaag tgataatgtg cgtactaaga agatcatcat
    21421 tccaaataag gcgacttatg agcgcgcttt agagttaact gacgagaaat accatgatca
    21481 gtttgtgcac ttgggttatc attaccagtt caaacgtgat aatttcctaa gacgagatgc
    21541 cttaatcttg accaattcag atcagattga gcaagtagaa gcaatcgtag aagccttgcc
    21601 tgatgttacc ttccgtatcg cagcagtgac agagatgtct tctaagctct tagacatgct
    21661 tcgctatcct aatgtggtcc tttaccagaa tgctagtcca cagaagattc aggagctgta
    21721 tcaactgtcg gatatttact tggatatcaa tcacagcaat gagttgttgc aggcagtgcg
    21781 tcaggccttt gagcacaatc tcttgattct tggatttaac caaacggttc acaatagact
    21841 ttatatcgct ccagaacatc tatttgaaag tagtgaagtt gctgccttgg ttgagaccat
    21901 taaattggcc ctttcagatg ttgatcaaat gcgtcaggca cttggcaaac aaggccaaca
    21961 tgcaaattat gttgacttgg tgcgatatca agaaataatg caaactgttt taggaggcta
    22021 acatgtcaga ggaagattta ttttacaaag acgttgaagg tcgcatggaa gagttgaaac
    22081 aaaaacccat caagaaggaa aaagaaaccc gaggggagaa gattagtaaa actttttcac
    22141 ttttactggg cttaatgatt ctgattggtt tgctctttac tttgttggga attttgaggt
    22201 agatcaatga ttgaaatgct aattgtttta gctattatcc tatctcttgc tttgattgta
    22261 ttggtaacta tacaaccccg tcaaaatcaa ctattttcca tggatgccac tagtaatatt
    22321 ggtaaaccaa gctactggca gagcaacacc ttggtcaagg tgctcacttt attggtgagt
    22381 ttggctttat ttgttctact attaaccttt atggtgatta cttataaata aaagaaaact
    22441 tcagatattc accttttgtg gattggtctg aagttttctt ttttatactc aatgaaaatc
    22501 aaagagcaaa ctaggaagct agccgcaggc tgctcaaaac actgttttaa ggttgtggat
    22561 ggaactgacg aagtcagctc aaaacaccgt tttgaagttg tagatagaac tgacgaagtc
    22621 agctcaaaac accgttttga ggttgtggat agaactgacg aagtcagctc aaaacaccgt
    22681 tttgaggttg tggatagaac tgacgaagtc agctcaaaac atcgttttga ggttgtggat
    22741 agaactgacg aagtcagtaa catatataca gcaaggcgac gctgacgtgg tttgaagagt
    22801 attactgtct atatttttgg taaaaatcaa cttttacttg gatgaaggtt ttggcttcac
    22861 gtaggagttg aagaagggtg gcgcgggttt caaattcttc tcttgtcttg ggcagactgc
    22921 ggttccggaa gacttccaga taacgttcaa tttcatctag caaatcagaa gcaggattgg
    22981 tctggctcag ttgacctgca atttttgaaa agagttgcgc taagatcagg ctttcactgg
    23041 cggcaaggtg acaagtgtta atctgttggg ccatgtttct caggatacga ctttgtcgtt
    23101 gtctcatctc aaagtagtgg atatggtagt cggtctggtg aaagaggtgg tcagagtgat
    23161 ccaaatagac cagtctgagg gcttctttca aaagcgtgtc taattctgct accagctgtg
    23221 ctcggttgcg tccgtctcct ctggataaat agtatttgaa gcgctggagg atatctttta
    23281 acttttcttc caccagcgtg tggtagtgct ggatttcctc ttctcgtgaa ggcatataga
    23341 gattaacaag caaggcaaat cctgtaccga tagcaaagag aaggaattcg ttgactagga
    23401 ggtctggaga ggttgactct tgaaccaaga gatggctaac caaaaccgtg cttggtgtga
    23461 tgccaatttc ccagcccatc ttgtaggcta aaggaacgta gaaggccaga tagaggccga
    23521 gactccagat atgaaatccg ctcaagtgaa aagctagaac accgatagcc agagctagaa
    23581 gcatagaaaa aagacgattg cgagccagtt ttaaagtact tctacgcgta tcagataggc
    23641 tcaagagagc gataattcca gccgaaactg ctgacgaaag attgagaaaa taagcaaaca
    23701 ggcaggcaag acaggtagct aagatgagct tggtcgtacg ttggctaata gacataagaa
    23761 tttcctaata agttagaata aaagcgtaaa agacaagaca tgagcaggct tgccttgatg
    23821 agttattttt tacgggttgc tgcgtattcg gcaacggcgg taaagaggac atctgtagaa
    23881 gagttaaggg ctgtttcaca tgagtcttgg atgacaccaa tcacaaaacc aaccccaaca
    23941 atttgtatgg caatatcgtt agaaataccg aaaaggctac aagcaactgg gataagaagg
    24001 agggaacctc cggcaatacc tgaagcacca caggctgaga tagctgctac cacactgagg
    24061 acaaaggctg tggcaaagtc aacaggaatt ccaagagtgt taactgtaac aagggtcaaa
    24121 aggttaatgg taatcgctac tccagccata ttgatagtag aaccgagtgg gatagaaaca
    24181 gaataggtat ctgggttgag tccaaggtca tggcagagtt tcatattgac aggaatgtta
    24241 gccgcagaac tacgagtgaa aaaggctgtc acaccgctga cacggaggca gttccaaact
    24301 agagggtaag gattgcgtct cataaagaag aaggcaatca aagggttgac cacaggggca
    24361 acaaaaagca tagtcgttac taatagaacc aataaaatac cgtagttggc aagccttccg
    24421 actcccttgt cagaaatggt tttaaaaaca agaccaagga ttccaaatgg agtcagattg
    24481 atgatccatt cgacaatttt agaagtcacg tcagcgatag tttttagcaa ttctttacta
    24541 tttttactgg cttctctcat agcgattcca aaaatgactg cccaagataa gattccaata
    24601 tagttagcag taagcagggc gttgactggg ctgtcaacca gtttgagcaa gaggttgctg
    24661 aggacctgcc caatcccatc tggtggtgca atttcagtat tggcactatt tagggtaatt
    24721 tcaataggga cgatgaaact tgctagtaca gctacaagag cagcggcgaa agtccctatc
    24781 ataggatata caagaaaaca acagttttca tattgctatc ttgtcccttt tgatgttggg
    24841 aaagggcatt ggcaacgaga gcaaagacta ggataggagc aacagctttt agacctccaa
    24901 cgaataaatc cccgagtagc ccaatccctg agagattagg aagggtcagt cctaggattc
    24961 cccacaaagc ataccaatca agatacgctt gacaaggctt gccttattcc aagcatgaat
    25021 gattcttttc ataataatct cctttttgtg tagtgattat gattatagta taaatgatag
    25081 acaaaatcaa gaattttctg tctatttttt gaatatttat ggagaatgag actgatgaaa
    25141 atatggtata atgaaataaa ggagttttat atgcaaaaat ttattcaggc ttatattgaa
    25201 aagctagatg tgacaaccat tatcgagaat attctaacca aggtcatttc tcttttactg
    25261 cttttgattg tattttatat tgctaaaaaa atgcttcata ccatggtgca gagaattgtc
    25321 aaaccttctc taaaaatgtc tcgtcatgat gtcggacgcc aaaaaaccat ctcacgttta
    25381 ctagaaaatg tgtttaatta tacgctatat ttctttttac tctactgcat tttgtcgatt
    25441 ttaggtttgc cagtttctag tttgctggct ggagctggta ttgctggggt agcgattggt
    25501 atgggagccc aaggctttct gtctgatgtc atcaatggct ttttcatcct ctttgaacgt
    25561 caactggatg tgggagatga ggtcgttctg acaaatggac cgattactgt atcgggtaag
    25621 gttgtcagtg tgggaattcg tacgacacag cttcgtagcg aggagcaagc ccttcacttt
    25681 gtccctaacc gaaatatcac agttgttagc aatttctcac gcacagacta gacctgttat
    25741 tttaagtaat ttgtggtaca atagagggag tttaataagg agaaaagatg gttttagaaa
    25801 agcagttggg ccatggttgt acctggatag acctagacct aggaaagttg aataaactag
    25861 aagacctttc tgaaatttac ggtttggaca aggaaaccat tgaatacgca ctggatagaa
    25921 acgagcgcgc ccacatggac taccaccgtg aaagtgggac ggttaccttt atctataatg
    25981 tcctagacgt aaaaaaggac aaggcctact atgagacttt tcccatgacc tttatcgtcg
    26041 agcatcgtcg cctgattacc attagtaata ccaagaacgc ctatgtcatt gaacagatga
    26101 ctcgttatct ggagagccat gacacgcttt cgatttataa gtttctcttt gccagtctgg
    26161 aaatcatcag caatgcctac tatcctgtca ttgagcagat ggacaagagt agggatgagg
    26221 tcaatgacct cttgcgccag cgaactacca agaaaaacct ctttgccctg tctgatttgg
    26281 agactggtat ggtttatctg acggcagctg ccaaacaaaa tcggattttg ttagagcata
    26341 ttcaaggtca tgccttgtat cgtagttttg atgagattga gagagaacag tttgatgatg
    26401 ccatgattga ggctcatcag ctggtatcca tgacagacct aatctctcag attttacagc
    26461 agctttcagc ctcttacaac aatattctaa acaataatct gaatgacaat ttgacaacct
    26521 tgactatcat ttcagtcttg ctagctgttt tggcagtcgt gacaggcttt ttcggaatga
    26581 atgttccctt acctttaaca gatgagcccc atgcttggct ctatatcagt ttggctagtg
    26641 caggtttgtg gattgtttta tccttgttac taaggaaaat tgcgaaaaaa agttaagaaa
    26701 aggagccaga atggcgattg aaaattatat accagatttt gctgtggaag cagtctatga
    26761 tctgacagtc ccaagcctgc aggcgcaggg aatcaaggct gttttggtcg atttggataa
    26821 taccctcatt gcttggaaca accctgatgg aacgccagag atgaagcaat ggctacatga
    26881 ccttcgggac gcgggtattg gcattatcgt agtgtcaaat aacaccaaaa aacgcgttca
    26941 acgagcagtt gagaaatttg ggattgatta cgtttactgg gccttgaagc ccttcacatt
    27001 tggtattgac cgtgccatga aggaattcca ctatgacaaa aaggaagtgg tcatggttgg
    27061 cgaccagctc atgacagata tacgagcagc ccaccgtgca gggattcggt caattttagt
    27121 caaacccttg gtccaacatg actcaatcaa aacgcagatt aaccgaactc gtgagcgtcg
    27181 tgttatgaga aaaatcactg aaaagtacgg accgattaca tataaaaaag gaatttaact
    27241 atggaagaaa ttctctgtat tggttgtgga gcaaccattc agacgacaga taaagctggt
    27301 cttggtttta ccccccagtc ggcacttgaa aaaggtttgg agactggcga agtctattgc
    27361 caacgctgtt tccgtctccg ccactacaat gaaatcacag atgtccagtt gacgaacgat
    27421 gatttcctca agctcttgca cgaggtggga gacagtgatg ccttagtggt caatgtcatt
    27481 gatatctttg attttaatgg atctgtcatc ccaggtttac cacgtttcgt ctcgggcaat
    27541 gatgtcctct tggtaggaaa taaaaaagat atccttccta agtcagttaa gtctggtaag
    27601 attagccagt ggctcatgaa acgtgcccat gaagaaggtc ttcgtccagt cgatgtggtc
    27661 ctaacttcag cacaaaataa acatgccatt aaggaagtca ttgataagat tgaacactac
    27721 cgtaagggcc gcgatgtcta tgtggtcggt gtgaccaacg ttggaaaatc aactctaatc
    27781 aatgctatta tccaagaaat cacgggtgat cagaatgtca tcactacttc acgcttccca
    27841 gggacaacct tggacaaaat agagattccg cttgacgacg gatcttatat ttacgatacg
    27901 ccgggaatta tccaccgcca ccagatggct cactacttga cggccaaaaa cctcaagtat
    27961 gtcagtccta aaaaggaaat caagcctaag acctatcagc ttaatcctga gcaaacccta
    28021 tttttaggtg gtttgggacg ctttgacttt atagcaggag aaaagcaagg atttactgct
    28081 ttctttgata atgaactcaa actccatcgt agcaagcttg aaggagctag tgctttctac
    28141 gataagcacc tgggaactct tctgacacca ccaaatagca aggaaaaaga agatttccca
    28201 aggctagtcc agcatgtctt taccattaaa gataagacag acctagtcat ttcaggccta
    28261 ggctggattc gtgtaacagg cacagcaaaa gtcgccgtct gggcaccaga aggcgtcgcc
    28321 gtcgccacac gaaaagcaat tatttaaaac aaaatcgctg agcgaacaaa gtgagctcat
    28381 atagcgatag ttattgccgt ggtgtgattg ccaatctgta gattggcaag gggcacaatt
    28441 gagaccaagg ctcaattgtg aggtcaggaa atccattttt caaagatgaa atctttggaa
    28501 aattagttcc gaccgtccct caccacctaa aataactatc aaaaaacaag gaagaaaatt
    28561 atgtcattag catcaaaaca acgtgccttc ctcaacagcc aggcacacac cctcaaacct
    28621 atcatccaaa tcgggaaaaa tggactcaac gaccaaatca aaaccagcgt ccgtcaagct
    28681 cttgatgcgc gtgaattaat caaggttact ctcttacaaa acacagatga aaacatccac
    28741 gaagtagctg aaattttgga agaagaaatc ggtgtggata cagtccaaaa aataggacgc
    28801 atcttgattt tgtttaagca atctagcaag aaagaaaatc gcaagatttc taagaaagtc
    28861 aaagaaatct aagaccgaaa ctccaaataa ctgtttttat agagaaataa aggggactag
    28921 cctatgacaa tcgaactatt gactcccttt accaaggtag agttggagcc agaaatcaag
    28981 gagaaaaaac gcaaacaagt tgggatttta ggggggaatt ttaaccctgt tcacaatgcc
    29041 catctcattg ttgcggatca agtacggcaa cagttgggac tggatcaagt tcttctcatg
    29101 cctgaatacc aacctcctca cgttgataaa aaggaaacca tccctgaaca ccatcgtctc
    29161 aagatgcttg agttggcaat tgagggaatt gacggcctag tcattgaaac cattgagttg
    29221 gagcgcaagg gtatttccta cacctacgac accatgaaga ttttgacaga gaagaatcca
    29281 gatacggatt attactttat catcggtgcc gacatggttg actatctgcc taagtggtac
    29341 cgaattgatg aactggttga catggttcag tttgtggggg ttcagcgtcc acgctacaag
    29401 gtagggactt cctatccagt tatctgggtg gacgtaccgc tcatggatat ctcgtccagc
    29461 atggtgcggg acttccttgc ccaaggtcgg aaacccaact ttctcctacc tcagccagtg
    29521 ctagactaca tcgagaagga ggggctctac tgatgtccta tcaagactat atcaactgct
    29581 cccgtgaggc cttgttggaa aaaatggcag agtttctacc tgagaaacgt ctaacccatt
    29641 gtctaggtgt ggagcgtgcc gctatggaat tagctcagcg ctttggtgta gatgttgaga
    29701 aagcaagtct agcaggtctt cttcatgact atgctaaaaa gttgtcaaat caggaatttc
    29761 tagccttgat tgaccgttac cagctagacc ctgacctcaa aaactggggc aataatgtct
    29821 ggcatggtat ggtcggaatt tacaaaattc aggaagattt ggatttgcat gattcagaaa
    29881 tcctgcgagc cattgaagtc catacagtcg gtgctggtca aatgacagac ctagataagg
    29941 tcatctacgt cgcagactat atcgagcaca atcgagcctt tcctggagta gatgtggcgc
    30001 gtgagattgc aaatctatcg ctcaataagg cggtggccta cgaaacagct cgtaccgtgg
    30061 agtatctagc tcatcaggga ttccccatct atccccaaac ccttgaaacc tataacgcct
    30121 ttgtgcacta tttgaaagag aactaaatga agacggcttt tataatcatt gatgttcaga
    30181 atattttagt agaaactggg ttccagacaa aaagtctatt gggaaaaatt tcttatttac
    30241 aaaaccaggc tagaagcaag aatattgaaa ttatctatgt tcaacatatt gagaactctg
    30301 aagctcaaac atcagaagat tggcagttat ctgcgctttt aaatcgaaaa cctgctgaaa
    30361 aggtctttca gaagaagtat aacagtattt tcaaagaaac tggcttaaaa gaatacttgg
    30421 ataagcaggg gattgaaaaa ttagttttat gtggtatgca gacagaatat tgtgtggata
    30481 cctctgtcaa ggttgccttt gaatatggct atcagcttat tgttccagaa ggtgctgtca
    30541 caacctttga tggggatgac attccagcag aaacgattaa tgaattttat gaggacattt
    30601 gggaggagcg ctttgcagat gttctagatt acaaacatat tttctaaaaa gaggattaaa
    30661 tgaacgaaaa agaattacta gaactagtcg tgaaagcggc tgatgagaaa cgtgcggagg
    30721 atatcctcgc acttgatgta caagatttga ctagtgtgac ggactacttt gtcatcacta
    30781 gctcaatgaa tagccgtcag ttggacgcta tcgcagctaa tatccgtgaa aaagtagctc
    30841 aagcaggctt taaaggtagc catgtcgaag gcgatgcagc tggaggctgg gtcttactgg
    30901 accttggtgc tgttgtcgtg catatctttt cagaagaaat gcgtgcccat tataatctag
    30961 agaagctatg gcatgaggcg aattcagtag atatttcaga agctcttgct tagaagatga
    31021 actcagttgt agtcaactgg gtttctttgc ttattttaga aaaattgata gaaaggtaaa
    31081 gggcctcgtg tttgtttcat ttcgaaactg aacacgagct aaaagctgag ataaaaagta
    31141 actttctttg tatctgacga tagggaagaa agtttcctat gtactctttg cttttaaggc
    31201 tctttgtatc ttagaaagga tttgaacccg tcctgtaatt ctcggaaaat agatagcctt
    31261 ccttggagct cggctccatc gtaaggctcc taattttcta tcgaattacg ggcggacttg
    31321 gtatcatgtt ttatggcgac ttatgaaacc tttgcggcgg tctatgatgc ggtcatggac
    31381 gatagtttat acgacaaatg gacgaatttt tctctgcgtc atttgcctaa gaccaaggag
    31441 agaaagaaac tcttggaatt ggcttgtggg acaggaattc aatcagtgcg cttttctcag
    31501 gctggttttg atgtgactgg acttgacttg agtgcggata tgttgaagat tgcggagaag
    31561 agagcaactt cagccaagca aaagattgct tttatagaag gtaatatgct gaatttgtcc
    31621 aaggcaggga aatacgattt tgtcacgtgt tattcggact ctatctgcta tatgcaggat
    31681 gaggtggaag taggggacgt ctttaaggac gtgtacaatg cgctgaatga agagggagtt
    31741 ttcatctttg acgtgcactc gacctaccag acagatgaag tattccctgg ctattcctac
    31801 catgaaaatg cggaagattt tgccatgctt tgggatacat atgaggacga agttcctcac
    31861 tccatcgtgc atgagctgac tttctttatc aaggaggctg acggttcctt tagtcgccac
    31921 gatgaagtac atgaggagag gacctatgag atcttgacct atgatatctt gctggaacag
    31981 gctggattta agtccttcaa actctatgca gactttgagg ataaggagcc aacagaaact
    32041 agcacccgtt ggttttttgt ggcgcagaag taggagatta gcatgaccat aacaggtatt
    32101 atcgcggagt tcaatccttt tcataatggc cataaatacc tgctggatca ggcagaggga
    32161 ctgaaaattg ttgccatgtc agggaatttc atgcagcgtg gagagcctgc tattgtggat
    32221 aagtggacaa gggcccagat ggcgctggaa aatggcgcag acttggtagt ggaattgccc
    32281 tttttagtca gtgttcaggc agctgatttc tttggtcaag gagctgtgga tatcttggat
    32341 cgcttgggca ttgatagtct agtttttggg acagaggaag ttctggatta ccagaaaatc
    32401 gctgacttat acacagagaa aggtgctgag atggagaaat ttgtgaaaaa tctgcctgat
    32461 tccctttcct atccccagaa aacccaagct atgtggaagg aatttgctgg tcttgatttt
    32521 tcaggtaata cccccaatca tgttcttgct ctggcctatg ccaaggcggt tgcaggacga
    32581 aatatcaagc tgcatccgat tcagcgtcag ggggcaggtt accattctgt gaataaagat
    32641 gtggactttg cctcggcgac agccctccgt caacatcaga aggaccaaga tttcttagaa
    32701 cgttttatgc cttctgttgc cctatttgag caggccagta aggtgatctg ggaagactat
    32761 tttcccttgc tccgctatca aatcttgtca aatcccgacc taaccaccat ctatcaggtc
    32821 aatcaagaaa tggctgtgcg cattaaagaa gctattaaaa cagcccagtc tgtggaagaa
    32881 ttggtcgagt tagtgactac caaacgttac accaaggcgc gtgtcagacg cctattgacc
    32941 tatattttgg tacaggctag agaaaatgtc ttgccagaag ccattcatgt ccttggattt
    33001 actgaaaaag tcaggcaaca tctcaagtct ctgaaaggac aggtcaatct agtcagccga
    33061 attggcaaag aaccttggga tgctatgacc caaaaagcag accagattta ccaactaggg
    33121 aagccaagta tagcagagca aaattttgga agagtgccga ttagaataga aacaaactaa
    33181 gtctaccgaa aggtaggctt tttgagattt tttacgaata atactcttcg aaaatcaaat
    33241 tcaaatcgcg tcaacgtcgc cttgccgtac tcaagtacag cctgcggcta gtttcctagt
    33301 ttgctctttg attttcattg agtataaata gatagaaaag aaaatcttgt acaagttcct
    33361 gacaatttct ttcttttcgt gtataatagt ggaaaagagc taaaacgagg tatggttatg
    33421 gaagcagtcc tttactcaac attccgaaat catttaaagg actacatgaa gaaggtaaat
    33481 gatgaatttg agcctttgac ggtggtcaat aaaaatccag atgaggacat tgtagttctt
    33541 tcaaagagcg aatgggacag tattcaggaa accctgagaa tcgcccaaaa taaggagtta
    33601 tcagacaagg ttttgcgagg aatggctcaa gtccgtgctg gaagcactca ggtccatgtg
    33661 attgaggagt gatgaatgct actcaagttt acagaagatg cctgggcaga ttattgctac
    33721 tgacaaaacc aagataaaaa aacactaaaa agaatcaata aattaatcaa ggatattcaa
    33781 cgcgatccat ttacaggaat aggaaaacca gagccactca aatatgatta ccaaggagcc
    33841 tggtcacggc gtattgatgc agaaaatcgc ttgatttata tgatggatgg agatagcgtg
    33901 gctttcttgt cctttaaaga tcattactaa gtctactgca aagtaggctt tttctcaagt
    33961 ctctactaaa ctactatttc taaacaacaa gtttattttg gtaaatgtgt tccaaattcc
    34021 ccaaaacata ttctatttta ggtttgtgaa aatcactttt ttatggtaga atgtaaaaga
    34081 atgtatgtca ttcggaataa caataaaatg aggtaaaaac atggaaatca tgtcgcttgc
    34141 gattgctgtt tttgccgtca tcattggttt agtcattgga tatgtcagca tctcagctaa
    34201 gatgaaatca tctcaggaag ctgcagagtt gatgctttta aatgctgaac aagaagcaac
    34261 taatttacgt ggacaagctg agcgtgaagc ggatttactt gttaatgaag ccaaacgtga
    34321 aagcaagtct cttaaaaaag aagcactatt ggaggccaaa gaagaagcca gaaaataccg
    34381 tgaagaagtg gacgctgaat tcaaatcaga acgtcaagaa ctcaaacaaa tcgaaagtcg
    34441 tttgacagag agagctacta gccttgaccg taaggacgac aatttgacga gtaaagaaca
    34501 aacacttgaa caaaaagaac aaagtatttc tgatagagcg aaaaaccttg atgcgcgtga
    34561 agagcaatta gaggaagtcg aaagacaaaa agaagcagaa ctagagcgta ttggtgctct
    34621 gtctcaggca gaagcacgag atattatctt ggctcagaca gaggaaaact tgaccaggga
    34681 gattgccagt cgcattcgcg aagctgagca agaggtcaag gaacgttctg acaaaatggc
    34741 caaggacatc ttggttcaag ctatgcaacg tatcgctggt gaatatgtag cggagtcaac
    34801 aaactcaaca gttcatctgc cagacgatac tatgaaggga cgcattattg gtcgtgaagg
    34861 tcgtaacatt cgtacctttg aaagtttgac aggggtcgat gtgattatcg acgatacacc
    34921 agaagtggtg accttgtcag gatttgatcc gattcgtcgt gagattgccc gtatgactat
    34981 ggaaatgttg ctcaaagatg gtcgtataca tccagctcgt atcgaagagt tggttgagaa
    35041 aaaccgtcaa gagattgaca ataagattcg tgaatacggt gaggctgctg cctatgaaat
    35101 tggtgcgcca aaccttcatc cagacttgat gaagattatg ggacgtttgc agttccgtac
    35161 ttcatatgga caaaatgttt tgcgccattc gattgaggtt gctaagttgg ctggtatcat
    35221 ggcgagcgaa cttggtgaaa atgcggctct tgcccgtcgt gctggattcc ttcacgatat
    35281 cgggaaagcc attgaccatg aggttgaagg tagccacgtt gaaatcggta tggaattggc
    35341 ccgtaagtac aaggaacccc cagttgtggt gaatacgatt gctagtcacc acggagatgt
    35401 tgaagctgag agcgtgatag cagttatcgt cgctgcagca gatgccttga gcgcagcccg
    35461 tccaggtgct cgtagtgagt ctcttgaaag ctacatcaag cgtctccatg atttggaaga
    35521 aattgctaac ggctttgaag gagtgcaaac tagctttgcc cttcaagcag gacgtgaaat
    35581 tcgtatcatg gtcaatccag gaaaaatcaa ggacgacaaa gtcacaatct tggctcacaa
    35641 agttcgtaag aaaattgaaa acaatctcga ttatccagga aatatcaagg taaccgtgat
    35701 tcgcgagctt cgtgcagtag attatgctaa ataaataaga aagagcagtt gaaaaattac
    35761 tgcttttttg ttacactaga tagaaagact gtaaaggata atctggcttt ttgccattat
    35821 tctagagaaa tgttatttca cagattgact aaaaggagac acaatggcag accgaggctt
    35881 actaatcgtt ttttctggtc cttcaggggt tggaaaagga acggttagaa gagagatttt
    35941 tgagagttct gaaaaccaat ttcaatattc tgtatcgatg acgacacgcg cacaacgtcc
    36001 tggagaagtg gacggtgttg actatttctt ccgtactcgt gaagaatttg aagagctgat
    36061 tcgtcaagga cagatgttgg aatacgcaga atatgtcggc aactactatg gaactcctct
    36121 gacctatgtc aatgaaacct tggacaaggg aatcgatgtt ttccttgaaa ttgaagttca
    36181 gggtgctctt caggtcaaga aaaaggttcc agatgctgtc tttatcttcc tgacaccacc
    36241 agatttggat gaattgcaag atcgcttggt aggtcgtgga acagatagtg cagaagtgat
    36301 tgcccaacga atcgaaaagg ccaaggaaga aattgccctc atgcgtgagt atgattatgc
    36361 gattgtcaac gatcaggtgc ccctagctgc tgaacgtgtc aaatgtgtga ttgaagcaga
    36421 acacttctgt gtggatcgtg tcattggtca ctatcaggag atgttaccaa aatctccaac
    36481 tacccgataa aatttagaaa ataggtacaa gcaaatgatg ttaaaaccct ctattgatac
    36541 cttgctcgac aaggttcctt caaaatattc actcgtaatc ttggaagcaa aacgtgccca
    36601 cgaattggaa gcaggtgccc cagcaactca aggtttcaag tctgaaaaat caactcttcg
    36661 cgctttagaa gaaatcgaat caggaaacgt tacaattcac ccagatccag aaggaaaacg
    36721 tgaagcagtg cgtcgccgta tcgaagaaga aaaacgccgc aaagaagaag aagaaaagaa
    36781 aatcaaagag caaattgcta aagaaaaaga agatggtgaa aaaatttaag gttgggggga
    36841 ctcaatctta ttttttctat tgcaagaatg tactgacaag gaggaggtga gaagatggcc
    36901 ctagctaaga ttatcgtaga tgtgcccttg atgcagacgg accagcccta tagttacagg
    36961 attccggagg aatttgaggg aatgctggaa gttgggatgc gggttcatgt gccttttggt
    37021 aagggtaatc gcctgattca agggattgtt cttggtttga agtcccaatc agatggagaa
    37081 gagatggagc aagatttaaa agatattgca gaggtgctgg atttttctcc tgttctcacg
    37141 ccagaacaac tctggctggc tgaggagtta cgcaaatctg tcttctccta caaaatctct
    37201 atcctcaagg ccatgcttcc agggtttctg aattctagct atgacaagat tctctatcct
    37261 ctggaaggct tgagtcagga agaacgagta cgcctgtttg gttcagaaga ttcgctagcc
    37321 ttttcttcac tagaccttgc caagcaagct gaaatgatgc gtttgactag aaaaggcctg
    37381 cttggtctgg aatatcaggc agtcgatcaa aagaaggtca agacccagtc ttggtatgag
    37441 gttgaccatg cccaattaga aggtgttgag atttctacac gtgccaagaa aaagttggaa
    37501 ctgagagatt atctgctgtc tcatccagag agcgcttcct tggctagctt gttagagtcc
    37561 tactcgcgag agcaagtcaa cttctttgtg gatcaaggta ctgttaccat agtccaaaag
    37621 gaagttcaac gctcggctgc ttattttgaa ggaattgaag caagtagacc tttggagtta
    37681 aatccagaac aaagacaggc gcgtgatgcg gttgtgagtt ctattggcag ttctcaacct
    37741 ccctttctac ttcaagggat tacaggaagt gggaagaccg aggtttactt gcagattatc
    37801 caaggtgccc tggataaggg taagacagct attttgctgg tacctgagat ttccttgact
    37861 cctcagatga ccgagcgttt tatagcacgt tttggggaca aggtagccat tcttcactca
    37921 ggattatcca atggcgaaaa gtatgatgaa tggcgcaagg tggagcgtgg cgatgcccaa
    37981 gttgttgttg gtgccagatc tgctatcttt gctcctctga aaaatctggg tgtcatgatt
    38041 attgatgaag agcatgaagc ggcttataag caggacagca atccccgtta ccatgccaga
    38101 gaggtagcta ttttacgggc tcagtataat caagcaactc tggtacttgg atctgcaacg
    38161 ccgagcttag agagccgggc acgtgctggc aaaggcgtct atcaacactt acgtctaacc
    38221 caacgtgcca atcctttggc tacaatccct gaggttcaag tgattgactt tcgagactat
    38281 atcggacaaa atgagacgtc aaactttacg cctcctttgc tagaggctat ccaagaccgt
    38341 ctggttaaaa aagagcaggt ggttctcatg ctcaatcgcc gtggttattc tagctttgtc
    38401 atgtgtcggg agtgtgggac ggtggatact tgtcccaact gcgatatttc tctgaccttg
    38461 catatggata ccaagactat gaactgccat tattgtggtt tctcgaagga tattcctcag
    38521 gtctgtccta actgtaagag ccgcagtatt cgttactatg ggacgggaac tcagaaggct
    38581 tatgatgagc tagcagaact ctttccccaa gctcgcattt tgaggatgga tgtggatacg
    38641 actcgaaaga aaggcagtca ccaagccttg cttgaccagt ttgggcgagg ggaagcggat
    38701 attttacttg gtactcagat gattgcaaag ggtttggatt ttcccaatgt taccctagtc
    38761 ggagttctaa atgcggatac ggccttgaat ctgcctgatt tccgttcttc tgagagaacc
    38821 ttccagctct tgactcaggt ggcaggtcga gcaggtcggg ctgaaaaagc aggtcaagtc
    38881 ttgatacagt cctacaattc gcagcactat gctattcgat ttgccaagga tcaagattac
    38941 gaaggctttt atgcctatga aatgggaatc agacgacaac tcggctatcc accttactat
    39001 ttcacgattg gtattaccct ttctcacaag aaagaagaag aggttttcaa acgtgcctat
    39061 gaagtcatga acattttgcg gtcaggcttg tcagagacca gtcccattct ggggccaacg
    39121 ccaaaaccga ttgcccgtac ccacaacctc tatcattacc agattttaat taaataccgt
    39181 ttagaagatg agctggggcc gaccctcaac caggtcttgg ccttgactca agaacgggaa
    39241 aatagtgagc tccgtctcag cattgaccat gagccgcagc aatttttata agaaggagaa
    39301 gatatgacaa aactaatctt tatggggacc cccgactttt cagcaacagt cttaaaagga
    39361 cttttgacag atgaccgtta cgaaattcta gccgttgtga cccagccaga ccgtgctgtt
    39421 ggtcgtaaaa aagttatcca agaaacccca gtcaagcagg ctgccaagga agcaggacta
    39481 tctatctacc aacctgaaaa attatctgga agtccagaga tggaagaact tatgaagcta
    39541 ggagcagatg gaattgtgac tgctgctttt gggcagtttc tcccaagcaa actccttgat
    39601 agcatggact ttgctgtcaa cgttcatgcc tccctccttc ctagacaccg tggtggtgcg
    39661 cctatccatt atgccttgat tcaaggggat gaggaagctg gtgtgaccat catggaaatg
    39721 gttaaggaaa tggatgcagg agatatgatt tctcgtcgca gcattccgat cacagatgag
    39781 gacaatgttg gcaccttgtt tgaaaaattg gcgctagttg gtcgtgattt gcttttggac
    39841 actctgcctg cctatattgc tggtgatatc aaacctgaac cgcaggatac gagtcaggtt
    39901 accttctctc caaatataaa gccagaggaa gaaaaactgg actggaacaa aaccaatcgt
    39961 caactcttta accaaattcg tggaatgaac ccctggcctg ttgcccatac tttccttaag
    40021 ggcgaccgct ttaagattta tgaagcccta ccagtagaag gtcagggaaa tccaggtgag
    40081 attctctcta tcggcaagaa agaattgatt gtcgcaacgg ctgaaggggc tctatccctc
    40141 aaacaagtgc agccagctgg taagcctaag atggacattg cttccttcct caatggagtt
    40201 ggacgtacat tgactgtagg agaacgattt ggtgactaaa gtagaaacgg ctagaagttt
    40261 agctctagca gtgctagagg atgtttttgt gaatcaagca tattcaaata ttgccttaaa
    40321 taaacacctc aaggggagtc agctctctgc agcagacaag ggcttagtga ccgagctagt
    40381 ctatggaacg gtagcccgta aactgactct ggaatggtac ctatcccact ttatcgaaga
    40441 cagagaccag ttagacagct ggctctatgt ccttcttctc atgagtgcct accaactccg
    40501 ctatttggac aagattccag atcatgctgt ggtcaatgaa gcagtggaat tggccaaact
    40561 ccgtaaaaaa ggcagtgaaa aattggtcaa cgctgtcctt cgccgtatct tgcgtgaagg
    40621 ctggccagat attgctagca tcaagcgaaa aaacaagcgt gactccattg cctattctct
    40681 cccagtttgg ctagttgcca aactcaagga agaatacgga gaggagagag caaaagccat
    40741 ctttgaaagc ctgttagtgc gaaacaaagc cagtattcgt gtaacagacc taagtcgaaa
    40801 agaggaaatc caagccttgt tggaggcgaa taattccctt ttagcaacca ctggtctggt
    40861 taaggagcag gggcattttg cagggcataa tttgtttgcg gatggagcca ttaccatcca
    40921 agacgagtcc agtcagttgg ttgctccgac gcttgattta caaggtgatg agcgagtgct
    40981 tgatgcctgt gcggctccag gtgggaaaac agcccatata gcctcttatc ttacgacagg
    41041 tcaggttact gctctggact tgtacgacca caagttggat ttaattcaag aaaatgccca
    41101 acgtctggga gttgaagatc gggttcaaac tcaaaaattg gatgccagaa aggtgcatga
    41161 gttttttgac caggattcct ttgataagat tttggtggat gctccttgtt caggaatcgg
    41221 tcttttgcgc cgaaaaccag atatcaaata caataaagaa acggcagatt tcgcgtcctt
    41281 gcaggaaatt cagttagaaa tattaggtag tgtttgtcaa atactaggca aaggtggtat
    41341 aataacttat agcacctgca ctatcgtctc agaggagaat tttcaagtcg ttaaggcctt
    41401 tttagagagt catcccgagt tcgagcaggt aaaactagaa catgaatgta aggatatcat
    41461 gaaagacggc tgtatcctca ttacacctga attgtatgga agtgatggat tcttcatcag
    41521 tcaatttcgc aagatatcgg attaggaagg aactgacaca tggaaatttc attattaaca
    41581 gatgttggtc agaaacgaac aaataaccaa gactatgtca accactatgt caatagagct
    41641 ggacgtacca tgattatttt agctgatggg atgggaggtc atcgtgcagg gaatatcgct
    41701 agtgaaatgg cggtcacaga cctgggtgta gcttgggttg atacccagat cgatacagtc
    41761 aatgaagtgc gtgaatggtt cgcccattac ctagaaattg aaaatcaaaa gattcaccag
    41821 cttggtcagg atgaagctta cagaggcatg ggaactactt tggaagtcct tgctattatt
    41881 gataatcagg ctatctatgc tcatattggt gattcgcgta tcggcttgat tcgtggagaa
    41941 gaataccatc agttgacgag cgatcattcc ttggttaatg aattgctcaa ggctggtcaa
    42001 ttgacaccag aagaggcaga agctcatccg caaaaaaata ttatcaccca gtctattggg
    42061 caaaaagatg aaattcagcc tgattttggg acagttatcc ttgagtcagg tgactatctc
    42121 ttgctcaata gtgacggctt gaccaacatg atttcaggca gtgagattcg tgatattgta
    42181 accagtgata ttcctttagc agataaaacg gagacacttg ttcgttttgc taacaatgca
    42241 ggaggtttag acaacattac ggttgccctt gtttttatga acgaggagga tgcagaatga
    42301 tccaaatcgg caagattttt gccggacgct atcggattgt caaacagatt ggtcgaggag
    42361 gcatggcgga tgtctaccta gccaaagact taatcttaga tggggaagaa gtggcagtga
    42421 aggttctgag gaccaactac cagacggacc cgatagctgt agctcgtttt cagcgtgaag
    42481 cgagagctat ggcagatcta gaccatcctc atatcgttcg gataacagat attggcgagg
    42541 aagacggtca acagtaccta gctatggagt atgtggctgg actggacctc aaacgctata
    42601 tcaaggaaca ttatcctctt tctaatgaag aagcagtccg tatcatggga caaattctct
    42661 tggctatgcg cttggcccat actcgaggaa ttgttcacag ggacttgaaa cctcaaaata
    42721 tccttttgac accagatggg actgccaagg tcacagactt tgggattgct gtagcctttg
    42781 cagagacaag tctgacccag actaactcga tgttgggctc agttcattac ttgtcaccag
    42841 agcaggcgcg tggttcgaag gcgactgtgc agagtgatat ctatgccatg gggattattt
    42901 tctatgagat gttgacaggc catatccctt atgacgggga tagcgcggtg accattgccc
    42961 tccagcattt ccagaaaccc ctgccgtccg ttattgcaga aaatccatct gtacctcagg
    43021 ctttagaaaa tgttattatc aaggcaactg ctaaaaagtt gaccaatcgc taccgctcgg
    43081 tttcagagat gtatgtggac ttgtctagta gcttgtccta caatcgtaga aatgaaagta
    43141 agttaatctt tgatgaaacg agcaaggcag ataccaagac cttgccgaag gtttctcaga
    43201 gtaccttgac atctattcct aaggttcaag cgcagacaga acacaaatca atcaaaaacc
    43261 caagccaggc tgtgacagag gaaacttacc aaccacaagc accgaaaaaa catagattta
    43321 agatgcgtta cctgattttg ttggccagcc ttgtattggt ggcagcttct cttatttgga
    43381 tactatccag aactcctgca accattgcca ttccagatgt ggcaggtcag acagttgcag
    43441 aggccaaggc aacgctcaaa aaagccaatt ttgagattgg tgaggagaag acagaggcta
    43501 gtgaaaaggt ggaagaaggg cggattatcc gtacagatcc tggcgctgga actggtcgaa
    43561 aagaaggaac gaaaatcaat ctggttgtct catcaggcaa acaatccttc caaattagta
    43621 attatgtcgg ccggaaatct tctgatgtta tcgcggaatt aaaagagaaa aaagttccag
    43681 ataatttgat taaaattgag gaagaagagt cgaatgagag tgaggctgga acggtcctga
    43741 agcaaagtct accagaaggt acgacctatg acttgagcaa ggcaactcaa attgttttga
    43801 cagtagctaa aaaagctacg acgattcaat tagggaacta tattggacgg aactctacag
    43861 aagtaatctc agaactcaag cagaagaagg ttcctgagaa tttgattaag atagaggaag
    43921 aagagtccag cgaaagcgaa ccaggaacga ttatgaaaca aagtccaggt gccggaacga
    43981 cttatgatgt gagtaaacct actcaaattg tcttgacagt agctaaaaaa gttacaagtg
    44041 ttgccatgcc gagttacatt ggttccagct tggagtttac taagaacaat ttgattcaaa
    44101 ttgttgggat taaggaagct aatatagaag ttgtagaagt gacgacagcg cctgcaggta
    44161 gtgtagaagg catggttgtt gaacaaagtc ctagagcagg tgaaaaggta gacctcaata
    44221 agactagagt caagatttca atctacaaac ctaaaacaac ttcagctact ccttaaaagc
    44281 agatggataa tcaaaatgag taatcaatct ttgtcatgat ttcatggcaa agattttttt
    44341 tgagtccgga tttgtgatag aatagaggga gttgataaaa ggaggaaagc atggaagaat
    44401 caaaagaatt aaatgccgtc attgatgtga ttatgctagc ggggactatt ctccttaaaa
    44461 gtggctcaga aatccatcgt gtagaagata ccatgattcg aatcgcgcat tcgcagggga
    44521 ttgtggattg caatgtcctt gccatgcctg ccgctatctt tttctctatt gaaaatacca
    44581 atatttcgcg catgaagcgc gtgacctcct cttcttataa catcgaaaaa gtctgcgatg
    44641 tgaaccagat ttctcgtcag ctagttgggg ggcagattga cttagaaaca gcctttaagc
    44701 aattgacggc cttgcaagct caaccccttc cctatactaa gttgcaggta actctggctg
    44761 cgacctttag tgctcctttc ttttcagtta tgtttagcgg aaatatctac gacgcacttg
    44821 gggcaggagt ggcgacctta tttggttttg ccttttccct ctatgtggaa aaatttatcc
    44881 gaattccctt tgtgacagcc tttgctggag cctttgtctt tgggataatt gcccagtttt
    44941 gggctcgcta cacaggtttt ccttcaacgg cagatttgat tatagctggt gcggtcatgc
    45001 cgtttgtacc aggtattgcc ttgaccaatg cggtccgtga tattatgacc aaccacataa
    45061 actctggtat gagtaagatg tttgaatccc tgctcattac cctcgcttta ggggcaggaa
    45121 cttctgtcgc cttggtattg atgaactaat atgacactaa caaccttttt attacaagca
    45181 gtagcaagtt ttcttgccat tatcactttt ttaatcgtac tcaatgtgca acggtctatg
    45241 ctcttacctg gagggatttt gggcatgact gtctggctaa tctatctctt gctcaaggaa
    45301 ccgaccaatg tcattgtagc taccttcatt gcagccatta ttggttcttg tgtcagccag
    45361 attttaagta ttctttataa gacacctgct gtggtcttta tcttggccat tttggcaccg
    45421 ctggttccag gttatctctc ctaccgaaca actgcctttt ttgtgacagg ggactataat
    45481 aaagcactgg caagtgcgac cttggttgtc atgttggctt tggtaatctc tattggaatg
    45541 gctagcggaa cagtgattct cagactgtat cattatataa aaacacatcg agtatcgtag
    45601 actttacaga aataaaagaa ttttctgaaa aatgagataa ataaattaac aacgctttct
    45661 atatgtgcga gaataccgca cttatgaaga aattgcggct gattttggta tccacgaaag
    45721 caacttactc cgtcggagcc aatgggttga agtaactctt gttcaaaggt ggtgttacga
    45781 tttcaagaac tcctctcagt tctgaagaca cggtaatgat tgatgcgacg gaagtaaaaa
    45841 tcaatcgccc taaaaaaaac aattagcgaa tgattctggt aaaaagaaat t
//
LOCUS       DAVAZV010000011        42428 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVAZV010000011 DAVAZV010000000
VERSION     DAVAZV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42428
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.011"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(98..739)
                     /gene="plsY"
                     /locus_tag="VQT46_000589"
     CDS             complement(98..739)
                     /gene="plsY"
                     /locus_tag="VQT46_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET2370666.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            875..2818
                     /gene="parE"
                     /locus_tag="VQT46_000590"
     CDS             875..2818
                     /gene="parE"
                     /locus_tag="VQT46_000590"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET2370667.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3238..5709
                     /gene="parC"
                     /locus_tag="VQT46_000591"
     CDS             3238..5709
                     /gene="parC"
                     /locus_tag="VQT46_000591"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET2370668.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            5841..6863
                     /locus_tag="VQT46_000592"
     CDS             5841..6863
                     /locus_tag="VQT46_000592"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET2370669.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            6919..7623
                     /locus_tag="VQT46_000593"
     CDS             6919..7623
                     /locus_tag="VQT46_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370670.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSDM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            7688..8377
                     /locus_tag="VQT46_000594"
     CDS             7688..8377
                     /locus_tag="VQT46_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET2370671.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8374..9297
                     /locus_tag="VQT46_000595"
     CDS             8374..9297
                     /locus_tag="VQT46_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET2370672.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9312..9956
                     /gene="pcp"
                     /locus_tag="VQT46_000596"
     CDS             9312..9956
                     /gene="pcp"
                     /locus_tag="VQT46_000596"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2370673.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10124..10354
                     /locus_tag="VQT46_000597"
     CDS             10124..10354
                     /locus_tag="VQT46_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET2370674.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10404..10484
                     /locus_tag="VQT46_000598"
     tRNA            10404..10484
                     /locus_tag="VQT46_000598"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10438..10440,aa:Tyr,seq:gta)
     gene            10494..10565
                     /locus_tag="VQT46_000599"
     tRNA            10494..10565
                     /locus_tag="VQT46_000599"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10526..10528,aa:Gln,seq:ttg)
     gene            10727..11929
                     /gene="rpsA"
                     /locus_tag="VQT46_000600"
     CDS             10727..11929
                     /gene="rpsA"
                     /locus_tag="VQT46_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET2370675.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12015..12512
                     /locus_tag="VQT46_000601"
     CDS             12015..12512
                     /locus_tag="VQT46_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET2370676.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12512..14167
                     /gene="dnaX"
                     /locus_tag="VQT46_000602"
     CDS             12512..14167
                     /gene="dnaX"
                     /locus_tag="VQT46_000602"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET2370677.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVSLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNVGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14195..14389
                     /locus_tag="VQT46_000603"
     CDS             14195..14389
                     /locus_tag="VQT46_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET2370678.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14539..15309
                     /gene="sufC"
                     /locus_tag="VQT46_000604"
     CDS             14539..15309
                     /gene="sufC"
                     /locus_tag="VQT46_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET2370679.1"
                     /translation="MSVLEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITRLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15337..16599
                     /gene="sufD"
                     /locus_tag="VQT46_000605"
     CDS             15337..16599
                     /gene="sufD"
                     /locus_tag="VQT46_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET2370680.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKINYLERLESRGEGSAKATANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16610..17836
                     /locus_tag="VQT46_000606"
     CDS             16610..17836
                     /locus_tag="VQT46_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2370681.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPASARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            17823..18263
                     /locus_tag="VQT46_000607"
     CDS             17823..18263
                     /locus_tag="VQT46_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET2370682.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18313..19725
                     /gene="sufB"
                     /locus_tag="VQT46_000608"
     CDS             18313..19725
                     /gene="sufB"
                     /locus_tag="VQT46_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET2370683.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(19956..21197)
                     /locus_tag="VQT46_000609"
     CDS             complement(19956..21197)
                     /locus_tag="VQT46_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET2370684.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITAYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFIDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21300..22409
                     /locus_tag="VQT46_000610"
     CDS             21300..22409
                     /locus_tag="VQT46_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2370685.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            22943..23290
                     /gene="ssrA"
                     /locus_tag="VQT46_000611"
     tmRNA           22943..23290
                     /gene="ssrA"
                     /locus_tag="VQT46_000611"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23473..23560)
                     /locus_tag="VQT46_000612"
     tRNA            complement(23473..23560)
                     /locus_tag="VQT46_000612"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23524..23526),aa:Ser,seq:gga)
     gene            23722..24462
                     /locus_tag="VQT46_000613"
     CDS             23722..24462
                     /locus_tag="VQT46_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2370686.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNITVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24459..25370
                     /gene="pfkB"
                     /locus_tag="VQT46_000614"
     CDS             24459..25370
                     /gene="pfkB"
                     /locus_tag="VQT46_000614"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET2370687.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25367..27319
                     /locus_tag="VQT46_000615"
     CDS             25367..27319
                     /locus_tag="VQT46_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2370688.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTDHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27483..29708
                     /locus_tag="VQT46_000616"
     CDS             27483..29708
                     /locus_tag="VQT46_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET2370689.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(29753..30181)
                     /locus_tag="VQT46_000617"
     CDS             complement(29753..30181)
                     /locus_tag="VQT46_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370690.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNIKKEPTTSQTTTIVKEIQKESPKENTSPTKETNTSQEKTQQEETPKSSVKE
                     EKKEDQKTATQDSSTPASSKPATENEKQSNAPTSENKSNQ"
     gene            30319..31461
                     /locus_tag="VQT46_000618"
     CDS             30319..31461
                     /locus_tag="VQT46_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2370691.1"
                     /translation="MIYFDNSATTKPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWLIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFAPVDKKGLVDVEALAGLIRHDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     NYPDIFVFSDEENFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            31470..32684
                     /gene="thiI"
                     /locus_tag="VQT46_000619"
     CDS             31470..32684
                     /gene="thiI"
                     /locus_tag="VQT46_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET2370692.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYTQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            32819..33643
                     /locus_tag="VQT46_000620"
     CDS             32819..33643
                     /locus_tag="VQT46_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2370693.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPGQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYFECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            33665..34404
                     /locus_tag="VQT46_000621"
                     /pseudo
     CDS             33665..34404
                     /locus_tag="VQT46_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            34417..35583
                     /locus_tag="VQT46_000622"
     CDS             34417..35583
                     /locus_tag="VQT46_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2370694.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIGRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMEQMIADFGQRQE"
     gene            36091..37584
                     /locus_tag="VQT46_000623"
     CDS             36091..37584
                     /locus_tag="VQT46_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET2370695.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37597..38643
                     /locus_tag="VQT46_000624"
     CDS             37597..38643
                     /locus_tag="VQT46_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2370696.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKRLITKRK
                     LQLDELNLLVKSRFNEMFGDVILNEKEWKVSKWNEILTIRNGKNQKQVEDADGKFPIY
                     GSGGIMGYAKDWIVKKNSVIIGRKGNINKPILVRENFWNVDTAFGLEPVLEKINSEYL
                     FYFCQLYNFEKLNKAVTIPSLTKSDLLNISIPLPPLALQNEFADFVALVDKSQFACEI
                     AIKVWRNSLKFSII"
     gene            38673..41369
                     /locus_tag="VQT46_000625"
                     /pseudo
     CDS             38673..41369
                     /locus_tag="VQT46_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            complement(41403..>42428)
                     /locus_tag="VQT46_000626"
     CDS             complement(41403..>42428)
                     /locus_tag="VQT46_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1167A family transposase"
                     /protein_id="HET2370697.1"
                     /translation="RRFKCYHCSKMMVAETPLVKKNHQIPRIINQKIAQKLIEKISMT
                     DIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYAFTKGKMSFIAQDFDNLNII
                     TVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYDLAKQLFPCAKIVLDRFHII
                     QHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTN
                     KEILDKILSYSEDLKHHYQIYQLLLFHFQNKDPEKFFGLIEDNLKQVHPLFQTVFKTF
                     LKNKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSQA"
BASE COUNT        12857 a         7608 c         9402 g        12561 t
ORIGIN      
        1 taaaactaaa aggacttagc cctgtgcaat acagaactaa atccttcgga taaattaatt
       61 gtctaacttt tggggtgcag ttcacagaac tggcatttta ttttttagga tcttgatggg
      121 ttaggttcaa tccccaaggg accaaatttt cagttttatt tttgatacga gctatattgt
      181 ccttatgacg aatgataatc aaactagcaa gtgctaagat aatagcgatg aagagagagt
      241 catagttact caggataaaa ccaaaaagtg gaaagagcag aaccccgata acagccgcga
      301 tcgatgctgt gacactagac agtgaaatca tactgccaag atagagagct ccaaagaaga
      361 taatcgcaag gtagagacag aagataggcg caaatccgaa aattactcca gcactggttg
      421 cgacagcctt accaccttta aatcctgcaa agatagggaa ggtatggccg ataacagcca
      481 aaagtccaaa gatgagagga gaaacgcctt gtagatgaaa aataatcgga agcagcgttg
      541 ctagggttcc tttgaaaaag tcaatcacaa aggttgccat accagctttc ttacctaaaa
      601 tgcggaaggt attggtcgtt ccagtgttac cagaaccatg ctcgcgtaga ttgatttgaa
      661 agaatacttg tccaatccag agaccagatg gaatcgaacc cagcagatag gctaggatta
      721 ataaaactat tgtaatcata ctcctattat atcatgaatt gggaaagaaa agcagagaat
      781 ctctgctaaa attgtcacat cggagaaaga aaaattttgc aaaatccttg gaaaacctgt
      841 agaatagtaa agatgaacga ataggaggtt ccttgtgtca aaaaaggaaa tcaatattaa
      901 caattataat gatgatgcta ttcaggtgct agaagggttg gatgcggtcc gaaaacgtcc
      961 agggatgtat attggatcga ccgatggcgc tggtcttcat cacctagttt gggaaatcgt
     1021 tgataatgca gtcgatgaag ccttgtctgg gtttggtgat cgtatcgatg taaccatcaa
     1081 taaagacggt agtctaacgg ttcaagacca tggacgtggg atgccgacag gtatgcacgc
     1141 tatgggaatt ccaactgttg aggttatctt taccattctt catgccggag ggaaattcgg
     1201 tcaaggtggc tataagacat caggtggact tcacggagtg ggttcttccg ttgttaacgc
     1261 cctttctagc tggttagaag ttgaaattac ccgtgatggc gcagtttaca agcaacgttt
     1321 cgaaaatggt ggaaaacctg tcacgacttt gaagaaaatc ggtacagcac ccaagtctaa
     1381 aacaggcacc aaagttactt ttatgcctga cgcgactata ttttctacga cagatttcaa
     1441 gtacaatacc atttcagagc gccttaatga atcagccttt ctcttgaaaa atgtgacctt
     1501 gtctttaacg gacaagcgaa cagatgaagc gattgagttc cactatgaga atggagtaca
     1561 agattttgtt tcttatctca acgaagataa ggaaatcttg acgccagttc tttactttga
     1621 aggggaagac aatggttttc aagtggaagt agccctccag tacaatgacg gattctcaga
     1681 taacattcta tcctttgtca ataacgttcg caccaaggac ggtggaacgc acgagacagg
     1741 actcaagtct gccattacca aggtcatgaa tgactatgca cgtaaaacag gtcttctcaa
     1801 ggaaaaagat aaaaaccttg aaggttcaga ctatcgtgag ggactagcgg ccgttctttc
     1861 tatcttagtt cctgaagaac acttgcagtt tgaaggacag accaaggata aactaggaag
     1921 ccccctagct cgcccagttg tggatggaat agtggctgat aagttgacct ttttccttat
     1981 ggaaaatggg gaattagctt ctaacctcat ccgcaaggct atcaaggccc gtgatgctcg
     2041 tgaagcagca cgtaaggcgc gtgatgagag ccgaaatggg aagaaaaaca agaaagataa
     2101 gggcttgttg tctgggaaat tgaccccagc ccaatctaag aatcctgcta agaatgaact
     2161 ctatctagtt gagggggact ctgccggtgg ttctgccaaa caaggtcgtg accgcaagtt
     2221 ccaggctatt ctacctcttc gtggtaaggt tatcaataca gccaaggcca agatggcgga
     2281 tatcctcaaa aatgaagaga tcaataccat gatttatacc attggtgcgg gtgttggagc
     2341 agacttctct attgaagatg ccaactatga taagatcatt atcatgaccg atgcggatac
     2401 cgacggtgcc catatccaga ccttgctctt gacatttttc taccgttaca tgcgtccgct
     2461 agtcgaggca ggtcatgtct atattgccct cccacctctt tacaagatgt ccaaaggtaa
     2521 aggaaagaaa gaagaagtgg cctacgcttg gacggacgga gaactagaag aactccgtaa
     2581 acagttcggt aaaggcgcta ccctccaacg atacaaagga cttggtgaga tgaatgcgga
     2641 ccagctctgg gaaacaacca tgaacccaga aacacgtacc ctcatccgtg tcacaattga
     2701 agatttagcg cgcgccgaac gccgcgtcaa tgttctcatg ggagataagg tagaaccacg
     2761 ccgtaaatgg attgaagata atgtcaagtt tacgctagaa gaagcgacag tgttttaatg
     2821 aaagaaaata atatgttagt aaactggaaa ttagagtcgg atgtgaatga ctatgtgaaa
     2881 aagcagtttg aaaatcttgg tttgaaaaaa ttgcaggatt attaatgaag aatctgctat
     2941 gagtgcttat ctcaaagagg cgcttaaggg agcggctaag acacaaacta agactaattt
     3001 tggaaaacca gattttcata ttgaaaaata caaacaggat agtttggtta cttatcgtaa
     3061 ctgaacacgg gaggaattcc cgtaaaatat cttttactgc ataaaaacct actctacatt
     3121 ctttgaaagg agttgaacac gccctagata ctgtgtgaaa aagataaatt ctcttgtgag
     3181 tttgcttact tcaagaattt tctattttca cttggtattt tatgggcttt gtatcttatg
     3241 tctaacattc aaaacatgtc cctggaggac atcatgggag agcgctttgg tcgctactcc
     3301 aagtacatta ttcaagaccg ggctttgcca gatattcgtg atgggttgaa gccggttcag
     3361 cgccgtattc tttattctat gaataaggat agcaatactt ttgacaagag ctaccgtaag
     3421 tcggccaagt cagtcgggaa catcatgggg aatttccacc cacacgggga ttcttctatc
     3481 tatgatgcca tggttcgtat gtcacagaac tggaaaaatc gtgagattct agttgaaatg
     3541 cacggtaata acggttctat ggacggagat cctcctgcgg ctatgcgtta tactgaggca
     3601 cgtttgtctg aaattgcagg ttaccttctt caggatatcg agaaaaatac agttcctttt
     3661 gcatggaact ttgacgatac ggagaaagaa ccaacggtct tgccagcagc ctttccaaac
     3721 ctcttggtca atggttcgac tgggatttcg gctggttatg ccacagacat tcctccccat
     3781 aatttagctg aggtcataga tgctgcagtt tacatgattg accacccaac tgcaaagatt
     3841 gataaactca tggaattctt gcctggacca gacttcccta caggggctat tattcagggt
     3901 cgtgatgaaa tcaagaaagc ttatgagact gggaaagggc gcgtggttgt tcgttccaag
     3961 actgaaattg aaaagctaaa aggtggtaag gaacaaatcg ttattactga gattccttat
     4021 gaaatcaata aggccaatct agtcaagaaa atcgatgatg ttcgtgttaa taacaaggta
     4081 gctgggattg ctgaggttcg tgatgagtct gaccgtgatg gtcttcgtat cgctatcgaa
     4141 cttaagaaag acgctaatac tgagcttgtt ctcaactact tatttaagta caccgaccta
     4201 caaatcaact acaactttaa tatggtggcg attgacaatt tcacacctcg tcaggttggg
     4261 attgttccaa tcctgtctag ctacatcgct caccgtcgag aagtgatttt ggcgcgttca
     4321 cgctttgaca aagaaaaggc tgagaaacgt ctccatatcg tcgaaggttt gattcgtgtg
     4381 atttcgattt tggatgaagt cattgctctt atccgtgctt ctgagaataa ggcggacgcc
     4441 aaggaaaacc tcaaagttag ctatgatttt acggaagaac aggctgaggc tatcgtaact
     4501 ttgcaactgt accgtttgac caataccgat gtggttgtct tgcaggaaga agaagcagag
     4561 cttcgtgaga agattgctat gctggcggct attatcggtg atgaaaggac tatgtacaat
     4621 ctcatgaaga aagaacttcg tgaggtcaag aagaaatttg caactcctcg tttgagttct
     4681 ttagaagaca ctgcgaaagc aattgagatt gatacagcta gtcttatcgc tgaggaagat
     4741 acctacgtca gcgtgaccaa ggcaggttac atcaagcgta ccagtccacg ttcctttgcg
     4801 gcttccacct tggaagaaat tggcaagcgt gatgatgacc gtttgatttt tgttcaatct
     4861 gccaagacaa cccagcacct cttgatgttc acaagtcttg gaaatgtcat ctacagacca
     4921 atccatgagt tggcagatat tcgttggaag gacatcggag agcatctgag ccaaaccatc
     4981 acaaactttg aaacgaatga agaaatcctt tatgtggaag tactggatca gtttgacgat
     5041 gcgacaacct actttgcagt gactcgcctt ggtcaaatca aacgggtaga gcgaaaagaa
     5101 ttcactccat ggcggaccta tagatctaag tctgtcaagt atgctaagct caaagacgat
     5161 acagatcaga ttgtagcagt ggctccgatt aaactagatg atgttgtctt ggttagtcaa
     5221 aatggttatg ccctgcgttt caatatcgaa gaggttccgg ttgtcggtgc taaggcagca
     5281 ggtgtcaagg ctatgaattt gaaagaagat gatgtcctcc aatctggctt tatctgtaat
     5341 acttcgtcct tctacctctt gacccagcgt ggaagcttga aacgtgtttc tattgaggaa
     5401 attctagcaa ccagccgtgc caaacgagga ttacaagtct tgcgtgagtt gaaaaacaaa
     5461 ccgcatcgtg tcttcttggc aggagcagtt gcagagcaag gatttgttgg cgatttcttc
     5521 agtacggaag tggatgtgaa cgaccaaact ctgcttgtcc aatccaataa aggaacaatc
     5581 tatgaaagcc gattgcaaga cttgaacttg tcagaacgca ctagcaatgg aagcttcatt
     5641 tctgacacga tttcagatga agaagttttt gacgcttatc ttcaggaagt agttactgaa
     5701 gataaataag tgaaatgaag aatcagttct aagagctggt ttttattgga gaaattttct
     5761 gaaaattaca aaatatactt gctattttag aaaaatagtg tagaatataa gaaataggtt
     5821 tttagaataa ggagtggaat atgacagtaa cgattgattg ggaaaacctc ggtttttcct
     5881 atatgaaatt accttatcgc tatcttgctc atttcaaaaa tggacaatgg gatcaaggag
     5941 agcttacaga ggatgcaact ttgcatattt cagagtcttc tccaagtctt cactatggac
     6001 aacaagcatt tgaaggtttg aaagcttatc gtactaagga tggcagtgtt caactgttcc
     6061 gtcctgatga aaatgctaaa cgtctgcaac gtacatgtga ccgtctcttg atgccacaag
     6121 ttccgacaga catgtttgta gaagcttgta aagcagttgt ccgtgcgaat gaagaatacg
     6181 taccaccata cggaacaggt ggaaccttat atcttcgccc tcttttgatt ggtgtcggag
     6241 atattatcgg ggtaaaaccg gcagaagagt acattttcac catctttgct atgccagttg
     6301 gaaattactt taaaggtggt ttggtcccaa ccaacttctt gattcaggat gagtacgacc
     6361 gtgcagcacc aaatggtaca ggtgcggcta aggttggtgg aaactatgct gcaagtctct
     6421 taccaggaaa aatggccaag tcacgtcatt tctcagatgt tatctatctg gacccatcaa
     6481 ctcatacaaa gattgaagaa gtcggatcag ctaacttctt tggaattaca gctgataatg
     6541 aatttgtaac accattgagt ccatctatct tgccatctat taccaagtat tccttgcttt
     6601 atttggcaga acatcgcttg ggattaactc ctattgaggg tgatgttcca attgataatc
     6661 ttgaccgttt tgtagaggca ggtgcctgtg gtacagcagc ggttatttct ccaattggag
     6721 gtattcaaca tggtgatgat ttccatgtat tctatagtga aacagaagta ggtcctgtga
     6781 cgcgtaaatt atataatgaa ttgacgggta ttcagtttgg cgatattgaa gcgccagaag
     6841 gttggattgt aaaagtagat taaaataaac caaaggagat tttttatgaa atagaaaaag
     6901 tggctcttaa cagcaggagt ggtcctgagc acgtcagcta ttttagtggc ttgtggaaaa
     6961 actgataaag aagcagatgc accgacaaca ttttcttatg tctatgcagt agatccagca
     7021 tcattgggct acagtatagc gactcgaaca tcgaggacag acgttattgg aaatgttatt
     7081 gatggtttga tggaaaatga taaatacggc aatgttgctc cttctcaaaa agactatgat
     7141 ttgaacagta caggatgggc tccaagctat caagatccag cgtcttactt gaatattatg
     7201 gatccaaaat ctggttctga catgaaacac cttggcatta cgaaaggaaa agataaggat
     7261 gttgtagcta aacctggttt ggataaatat aagaaattgt tagaagatgc tgtttctgag
     7321 accactgacc tagagaagag atatgaaaaa tatgccaaag ctcaagcttg gtcgacagat
     7381 agttcattat tgatgccaac agcttcatct ggtggttttc cagttgtaag taacgtagta
     7441 ccattctcaa aaccatactc acaagttggt attaaggggg aaccatatat ctttaaagga
     7501 atgaaattgc aaaaagatat tgttacaaca aaagaatata acgaggtttt taaaaaatgg
     7561 caaaaagaaa aattggaatc caatagcaaa taccaaaaag aactagaaaa atacattaaa
     7621 taaggaatgg tattgatctt gataaaattt ttaaaatact gtcattttga atataaagga
     7681 gtttgatatg gagtggatta gattaatagg aatagcaatc attgttgtgg gttttatttt
     7741 aaaatttgat acaattgcaa cagtagtctt agctggtttg gttacagctt tagtttcagg
     7801 tgtttctctc gttgaatttt tggagatttt gggaaaagaa tttagcaatc agcgagtgct
     7861 cacgattttt atggttacct tgcctcttgt ggggctgtca gaaacctttg gactcaagca
     7921 acgatcaatc gatttgattc gaaagattaa aggtctgaca gttggaaact tctatacagt
     7981 ttatttcttt attcgagagt tagctggttt cttttcaatt cgtctaggag gacaccctca
     8041 gtttgtcaga cctttggttc aacctatggg agaagcagct gcagagtctc aattaggtag
     8101 aaagttaaca gaggttgaag atgagacaat aaaagcgcgt gcggctgcga atgaaaattt
     8161 tggaaatttc tttgctcaaa atacgtttgt aggtgctggg ggagtcctct tgataggggg
     8221 aacattagat cagttaggct atgaaagcaa ttatgcaggg attgcttcta catctattat
     8281 tgttgctgtt ataacactta ttgtagtggg gatttacaat tatttatttg ataaaaaatt
     8341 gatatcaaaa aagactaggg gaggagaaca aaaatgacag agttggcaaa gcaactatta
     8401 gagttgacct atattgtgat tggttgtcaa tttctccata cagcctattg tagttataaa
     8461 gataaaacaa acccagttcg acttgggaca tctgcatttt ggactctatt gtctattacg
     8521 tttataggtg gttcctatat gccaaatatg agtattggta ttattgtaat cctattatcg
     8581 ctgttaacat tgtttaagca agtccgtatc ggaaccttgc catccttaga tgaaatgaaa
     8641 gccaatattg aatctaacag gttgaaaaat aaaattttta ttccagttat gctgatggca
     8701 atacttgcgt tggtcttagc gcaaatgatt ccagaattta gcaagatttc gattagcctt
     8761 gccgccttgt ttgctacaat ttctgttctt gtgattacca atagtcaccc taagagtctg
     8821 ttatcagaaa ataatcgaat gactcagcaa gtttcaacaa gtgggattgt tcctcaatta
     8881 ttaggggctt tgggggctat ttttactgta gcaggtgttg gtgatgttat ctctcatctg
     8941 attagcggta ttgttccttc agatagtcgc tttataggag ttttggctta tgttcttgga
     9001 atggttctat tcacaatgat tatgggaaat gcttttgcag cattcaccgt tattacagca
     9061 ggtgttggag ttccctttgt atttgctctg ggagctaatc caattgtggc tggtgctctt
     9121 gccatgacag caggttattg tgggacctta ttgaccccaa tggctgctaa ttttaacgct
     9181 ctaccagcag cattgatgga tatgaaagat cagaatggcg ttataaaggc tcaagcaggt
     9241 gttgctctag taatgattgt tattcacata ttcttaatgt actttctcgc attttagtaa
     9301 aggaaaataa aatgaaaata ttggttacag gttttaatcc ttttggaggt gaaaagatta
     9361 atccagcttt ggaggctgta aaattattac catctgagat taatggggct gaagttcgct
     9421 gggtagaaat tccaacggtt ttttataagt cgtcagaagt tttagaggca gaaatattac
     9481 gatatcaacc agatgctgta ctttgtattg gacaagcagg cggcaggacc ggcttaacac
     9541 ctgaacgagt ggctattaat caagatgatg ctcgcatacc tgataacgaa ggcaatcaac
     9601 caattgatac accgattcgt attgatggag catcggccta ttttagtagt ttacctatca
     9661 aagcgatggt acaagctatc aaaaaacagg gacttccggc agttgtatcc aatagtgcag
     9721 gaacctttgt ttgcaatcat ttgatgtacc aagctcttta tttagtggat aaaaaattcc
     9781 ctaatatgag agcaggtttc atgcatattc catatatgat ggaacaagta gtaaataagc
     9841 cgaatactgc aggaatgagt ctatgtgata ttgtaagagg catagaggta gctattgaag
     9901 ctattgtaga ctacaaagat aaggatttgc agttagtagg cggtgagact cactgataac
     9961 ctaaaaagga tagtcaatta tgcttgttta ctaactatta actatgctaa atcaattgag
    10021 gttgtttaca taaaactcta tatcagagaa gcctgatata gagttttttc ttgctagttt
    10081 taggattttc ttgtaaaata gaaaaagtga agagaggtat gaaatgagca agaaagataa
    10141 aaaaatcgaa attcaagtag cggatgccaa agttaatgtt ggtaaagaca gttttgaagg
    10201 ttatacattg actatcggta aaaaagttat cggagaaatt gccgaattag acggacaatt
    10261 tgccattata aagaatggga atgtcgatag tttttataaa aaattggaaa aagctgtgga
    10321 aattttgatt gaaaattata atttagcaaa ataagtcttg tttttttgaa attttcatga
    10381 tataatagtc catgttgatt gtaggagaga tagcgaagag gctaaacgcg gcggactgta
    10441 aatccgctcc ttcgggttcg ggggttcgaa tccctctctc tccatttcat taatggggta
    10501 tagccaagcg gtaaggcaag ggactttgac tccctcatgc gttggttcga atccagctac
    10561 cccagttctt aggtaataat caagataaaa agcaaaatat cttagggtat tttattttta
    10621 taattgaaag acgtgaatga tatgaacatg tccttgcggg tgcttaggaa aaaaattata
    10681 agtatgtcaa gtttaagaaa aacttgattg ttggaggatt ttttagatga acgaatttga
    10741 agatttgcta aatagcgtta gtcaagttga gactggtgat gttgttagtg ctgaagtatt
    10801 gacagttgat gcgactcaag ctaacgttgc aatctctgga actggtgttg aaggtgtctt
    10861 gactcttcgc gaattgacaa acgatcgtga tgcagatatc aatgactttg ttaaagtagg
    10921 agaagtattg gatgttcttg tacttcgtca agtagttggt aaagatactg atacagttac
    10981 ataccttgta tctaaaaaac gccttgaagc tcgcaaagca tgggacaaac ttgttggtcg
    11041 cgaagaagaa gttgttactg ttaaaggaac gcgtgccgtt aaaggtggac tttcagtaga
    11101 atttgaaggt gttcgtggat ttatcccagc ttcaatgttg gatactcgtt tcgtacgtaa
    11161 cgctgagcgt tttgtaggtc aagaatttga tactaaaatc aaagaagtta acgctaaaga
    11221 aaaccgcttc atcctttcac gtcgtgaagt tgttgaagca gctactgcag cagctcgcgc
    11281 tgaagtattc ggtaaattgg ctgttggtga tgttgtaact ggtaaagttg ctcgtatcac
    11341 aagcttcggc gctttcatcg accttggtgg tgttgacgga ttggttcact tgactgaatt
    11401 gtcacatgaa cgtaacgtat caccaaaatc agttgtaact gttggtgaag aaattgaagt
    11461 gaaaatcctt gatcttaacg aagaagaagg acgtgtatca ctttcactta aagcaacagt
    11521 accaggacca tgggatggcg ttgagcaaaa attggctaaa ggtgatgtag tagaaggaac
    11581 agttaaacgt ttgactgact tcggtgcatt tgttgaagta ttgccaggta tcgatggact
    11641 tgttcacgta tcacaaattt cacacaaacg gattgaaaat ccaaaagaag ctcttaaagt
    11701 tggtcaagaa gttcaagtta aagttcttga agttaacgca gatgcagaac gcgtgtcact
    11761 ttctattaaa gctcttgaag aacgtccagc ccaagaagaa ggacaaaaag aagaaaaacg
    11821 tgctgctcgt ccacgtcgtc caagacgtca agaaaagcgt gatttcgaac ttccagaaac
    11881 acaaacagga ttttcaatgg ctgatttgtt tggtgatatc gaactttaat caaattgaaa
    11941 attcacaaaa tcctttgttt actaaacaag ggatttttct tttgtctctg ctcctttttt
    12001 gatataatag ttctatgtta aaatcagaaa aacaatcacg ttatcaaatg ttaaatgaag
    12061 aattgtcctt cctattggaa ggcgaaacca atgttttggc taatctttcc aacgccagtg
    12121 ctcttataaa atcacgtttt cctaataccg tatttgcagg cttttatttg ttcgatggaa
    12181 aggaattggt tttaggtccc ttccaaggag gtgtttcctg catccgtatt gcactaggca
    12241 agggtgtttg tggtgaggca gctcactttc aggaaactgt tattgttgga gatgtgacga
    12301 cctatctcaa ctatatttct tgtgatagtc tagctaaaag tgaaattgtg gtgccgatga
    12361 tgaagaatgg tcagttactt ggagttctgg atctggattc ttcagagatt gaggattacg
    12421 atgctatgga tcgagattat ttggaacaat ttgtcgctat tttgcttgaa aagacaacat
    12481 gggactttac gatgtttgag gaaaaatctt aatgtatcaa gcactttatc gaaaatatag
    12541 aagtcaaaac ttctcccagt tagttggtca agaagttgtg gctaagactc ttaaacaagc
    12601 ggtggagcaa gagaaaataa gtcacgctta tcttttttct ggtcctcgtg gaacgggaaa
    12661 aaccagtgtt gctaaaatct ttgccaaggc tatgaactgt cccaatcaag tgggtggcga
    12721 accttgcaat aactgctata tttgtcaagc agtgacggac ggtagtttag aagatgtcat
    12781 tgaaatggat gcagcttcta ataatggggt agatgaaatt cgcgaaattc gtgataaatc
    12841 tacctatgcg cctagccttg ctcgttataa ggtttatatc atagatgagg ttcacatgct
    12901 gtctacaggg gcttttaatg ccctcctaaa gacgctggaa gaaccaacac agaatgtagt
    12961 ctttattttg gccactactg aattacacaa gattcctgct actattctat cccgtgtgca
    13021 acgttttgag tttaaatcaa ttaagacaca ggatattaag gaacatattc actatatctt
    13081 agaaaaagaa aatatcagtt ctgaaccaga ggctgtggaa atcattgcca gacgggcgga
    13141 aggtggaatg cgggacgcct tgtctatttt ggatcaagcc ctgagtttga cacagggaaa
    13201 tgagctgacg actgctatct ctgaagaaat tactggcact attagcctat cagccttgga
    13261 tgattatgtg gcggccttgt ctcaacagga tgttcccaaa gctttgtctt gcttgaatct
    13321 tctttttgac aatggtaaga gcatgactcg ttttgtgacc gatcttttgc actatttaag
    13381 agacttgtta attgttcaaa cagggggaga aaatactcat catagttcag tctttgtaga
    13441 aaatttggca cttcctcaaa aaaatctgtt tgaaatgatt cgcttagcaa cagtgagttt
    13501 agcagatatt aagtctagtt tgcagcccaa gatttatgct gaaatgatga ccgtccgttt
    13561 ggcggaaatc aagcccgaac cagctctatc aggagcggtt gaaaatgaaa ttgctacgct
    13621 gagacaggaa gttgcccgtc tcaaacaaga gctttctaat gtaggtgcgg ttcctaaaca
    13681 agttgcacca gctcctagtc gaccagctac gggcaaaaca gtctatcgtg tcgatcgcaa
    13741 taaagtgcaa tctatcttac aagaggccgt cgaaaatcct gatttagcac gtcaaaatct
    13801 aattcgtttg cagaatgcct ggggagaggt aattgaaagt ctaggtgggc cggacaaggc
    13861 tctgctagtt ggttctcaac cggttgctgc caatgaacac catgctattc ttgcttttga
    13921 gtctaacttc aatgctggtc aaactatgaa acgagacaat ctcaatacca tgtttggcaa
    13981 tatcctcagt caggcggcag gtttttcacc tgagatttta gctatttcca tggaggaatg
    14041 gaaagaagtt cgcgcagcct tttcagccaa agccaaatct tctcaaactg aaaaagaagt
    14101 agaagaaagc ctgattccag aaggatttga atttttggct gataaagtga aggtagagga
    14161 agactaaaga aagatttcgt gatacaataa gtttatgaat aaacaacaat ttattattat
    14221 ggcgctgttt acagctgctg agacctattt tttcaatgaa gcctggatga ctggccgcta
    14281 tattatggca gccttttggg caattttact ctttagaaat ttccgagtca gttatgtgat
    14341 gggcaaaatc gttgatgtca tcgatcagca ttttaatagg aaagactagc cctcagcttc
    14401 cagacaaaat caaagccttt taggcttttt tttgttatac tagaaaagta tatttataga
    14461 atttttgctc tatttctggg gaaatcagac gtttttctag taagtactgt aaaagttttg
    14521 aaaaagaaag gaactatcat gtcagtatta gagatcaaag atcttcacgt tgagattgaa
    14581 ggaaaagaaa ttttaaaagg ggttaacctg accctgaaaa caggagaaat tgccgctatc
    14641 atgggaccaa atggtacagg taaatcgact ctttctgccg ctatcatggg aaatccaaac
    14701 tatgaagtaa ctaaaggtga agttttgttt gatggcgtaa acatccttga gttggaagtg
    14761 gatgagcgtg cgcgtatggg acttttcctt gctatgcaat acccatcaga aatccctgga
    14821 attaccaatg ctgagtttct tcgtgccgct atgaatgcgg gtaaagaaga tgatgagaag
    14881 atttcagttc gtgagtttat tactaggcta gatgaaaaaa tggaattgct caacatgaaa
    14941 gaagaaatgg cagagcgtta cctcaacgaa ggcttctctg gtggtgagaa aaaacgcaat
    15001 gaaattcttc aacttttgat gttggagcca acatttgctc ttttggacga gattgactca
    15061 ggtcttgata ttgacgctct taaagttgtg tctaaaggtg tcaatgccat gcgtggtgaa
    15121 ggttttggtg ctatgatcat cactcactac caacgtcttt tgaactatat cacacctgat
    15181 gtggtacacg tgatgatgga aggtcgtgtt gtcctttctg gtggtccaga attggctgcg
    15241 cgtttggaac gtgaaggata cgcaaaatta gctgaagaac ttggctacga ctacaaggaa
    15301 gaattgtaat ttcctcgtat cttttaggag aagtaaatga ctagagaaaa tattaaactt
    15361 ttttcagaaa tgcacgctga accaagctgg ttggctgatc tccgtcaaaa agcttttgac
    15421 aagattgaga ctttggaatt accagttatt gagcgtgtca aattccaccg ttggaatctg
    15481 ggtgatggaa cgattacaga aaatgagcca tcagcaaatg ttccagattt cacagcttta
    15541 gatcatcact tgaagttggt gcaagtagga actcaaactg ttttcgaaca aactccagtt
    15601 gagttagctg aacagggtgt tgtcttcaca gactttcact cagctttaga agaaattcca
    15661 gagctgatcg aagaattctt catgtcatct gttaagtatg atgatgacaa gttggcggct
    15721 taccacacag cttactttaa cagtggtgct gtactctata ttccagataa cgtagaaatc
    15781 acagagccaa ttgaaggaat tttctaccaa gatagcgata gcaatgtgcc gtttaacaag
    15841 catattatga ttatcgctgg taaaaattct aagattaatt atctggagcg tttagagtca
    15901 cgcggtgaag gaagtgccaa agcaactgct aatatcacag tagaagtgat tgcacgttca
    15961 ggtgcgcaag tcaagtttgc tgctatcgac cgtctaggtg aaaacgtcac tgcctacatt
    16021 agccgtcgtg gtaaattagg caacgatgca agtattgact gggctatcgg tgtcatgaac
    16081 gaaggaaatg tcgttgctga ttttgatagt gacttgattg gtaatggtag ctatgctgac
    16141 ctcaaggttg tagctctttc aagtggtcgt caggtacaag ggattgatac tcgtgtaact
    16201 aactatggct gcaactctat cggaaatatc ctacaacatg gggttatcct tgaaaaagca
    16261 actttgactt tcaatggtat cggccacatc atcaagggtg ctaagggagc agatgcccaa
    16321 caagagagcc gtgttctcat gctttcagac caagcgcgtt cagatgctaa cccaattctt
    16381 ttgattgatg aaaatgatgt cactgcagga cacgcagcgt ctatcggaca agttgatcca
    16441 gaagacatgt attacctcat gagtcgtgga ttggataagg caactgcaga gcgtttggtt
    16501 gttcgtggtt tccttggatc tgttatcgtg gagattccag tcaaggaagt tcgtgatgaa
    16561 atgattgcaa ctatcgaaga gaaattgtca aaacgctaag gggaagccta tgttagatgt
    16621 agaagcgatt cgcaaggatt ttccaatttt agatcagatt gtcaatgatg aacctctggt
    16681 ctatctggac aatgctgcga cgacacaaaa accactagta gttctgaaag ctattaacag
    16741 ttactatgag caggacaatg ccaatgttca ccgtggtgtc cataccttag cggaacgagc
    16801 gacagcttct tatgaagctg ctcgtgaaac cattcgtaag tttattaatg caggctctac
    16861 aaaggaagtt ctctttacca gaggaacgac aaccagcctt aactgggtgg cacgctttgc
    16921 tgaggaaatt ctcactgagg gagaccaggt cttgatttca gtaatggaac accattctaa
    16981 tatcattcca tggcaggaag cttgtcgaaa gactggagca gagcttgtct atgtctatct
    17041 taaagacggt gccttggata tggaggattt gcgagctaaa ttgactgata aggttaaatt
    17101 tgtttcccta gctcatgcct ccaatgttct tggtgtggtc aatccgatca aggaaatcac
    17161 tcaattagcc caccaagttg gggcaatcat ggtagtggat ggtgctcaat ctacacctca
    17221 tatgaagatt gatgtccagg acttggatct ggactttttc gccttttcgg gtcacaagat
    17281 ggctggtccg actggtatcg gtgtccttta cggcaaagaa aagtatcttg agcaaatgtc
    17341 tccagtagaa tttggcggcg agatgattga ttttgtctac gagcaatccg ctagttggaa
    17401 ggaattgcct tggaaatttg aggctggaac gccaaatatg gcaggagcta ttggacttgc
    17461 gactgcagtt gattatctgg aaaagattgg tatggatgcc gttgaagctc atgaacagga
    17521 attgattgcg tacgtctatc caaaactgca ggcaattgag ggattgacca tttacggttc
    17581 tcaggatttg gctcaacgtt cgggtgttat tgcctttaac ctaggtgatc tccatcctca
    17641 cgatcttgcg acggctctgg attatgaagg agtggctgtt cgtgctggtc accattgtgc
    17701 gcaacccttg cttcagtatt tggaagtccc agcatcagct cgtgcaagtt tttatatcta
    17761 taataccaag gcagattgcg acaaactagt cgatgcccta caaaagacaa aggagttttt
    17821 caatggcact ttctaaacta gatagccttt atatggcagt ggtagcagac cattcgaaaa
    17881 atccacatca ccaagggaag ttagaagacg ctgagcaaat cagtctcaac aatccgactt
    17941 gtggggatgt catcaacctc tctgtcaagt ttgatgcaga ggaccgtttg gaagatattg
    18001 cttttctaaa ttcaggatgc acgatttcaa ctgcttctgc tagtatgatg acagatgccg
    18061 ttttaggaaa aaccaaacaa gaaattttag aactggcgac tattttttct gaaatggttc
    18121 aagggcaaaa agatgagcgt caagaccaac ttggagacgc ggcattcttg tcaggtgttg
    18181 ccaaattccc tcaaagaatc aagtgtgcaa ccctagcttg gaatgccctt aagaaaacaa
    18241 ttgaaaatca agaaaaacag taagacaagt ttcttttgtc ttatgaatta ttagaaatga
    18301 agaaaggata ttatggctga agaaagagta gaaccaaaac caattgacct tggtgaatat
    18361 aaatttggtt tccatgacga tgtagagcct gtcttatcga caggaaaagg actcaacgaa
    18421 ggtgttattc gtgaattatc tgctgctaag ggtgagcctg agtggatgtt ggagttccgt
    18481 ttgaagtctt atgaaacctt caaaaaaatg cccatgcaaa cttggggagc agacttgtca
    18541 gagattgact ttgatgactt aatctactac caaaaaccat ctgacaaacc agcccgttct
    18601 tgggatgatg tacctgaaaa gattaaagaa acctttgaac gtatcgggat tccagaagct
    18661 gaacgtgctt atttagcagg ggcttctgcc cagtacgagt cagaagtggt ttaccacaac
    18721 atgaaggaag agttccaaaa attaggtatt atctttacag atacagattc cgcactcaag
    18781 gaatacccag acttatttaa acaatacttt gcgaagttgg taccgccgac agataacaag
    18841 ttggcagccc tcaactcagc agtatggtcg ggtggaactt ttatctacgt gccaaaaggt
    18901 gtcaaggtag atattccact tcaaacttat ttccgtatca ataacgaaaa tataggtcag
    18961 ttcgaacgta ccttgattat cgttgatgag ggagcaagcg tccactacgt agaaggatgt
    19021 acagcaccaa catattcaag caatagcttg cacgctgcca ttgtagaaat ttttgctttg
    19081 gacggagctt atatgcgtta tacaactatc caaaactggt ctgataacgt ctataacttg
    19141 gtaacaaagc gtgctaaggc tcaaaaggat gccactgttg agtggattga tggaaacttg
    19201 ggtgccaaaa cgactatgaa atatccatct gtttatcttg atggagaagg agcgcgtggt
    19261 accatgctct ctatcgcctt tgctaatgca gggcaacacc aagacacggg tgctaagatg
    19321 attcacaatg ctccacatac cagctcgtct attgtgtcta aatccatcgc taaaggtgga
    19381 ggaaaggttg actaccgtgg acaagtcacc tttaacaaga actctaagaa atctgtttcc
    19441 cacattgaat gtgataccat tatcatggat gacttgtcag catcagatac tattccattt
    19501 aatgaaattc acaactcgca agtggctttg gaacacgaag ccaaagtatc taagatttca
    19561 gaagagcaat tgtattatct catgagccgt ggattgtcag aatctgaggc aactgaaatg
    19621 attgtcatgg gatttgtaga accctttaca aaagaacttc caatggaata cgcagttgag
    19681 ctgaaccgct tgattagcta tgaaatggag ggatcagttg gataaaattt gattttatac
    19741 tcttcgaaaa tctcttcaaa ccacgtcagc atcgccttac cgtatgtatg gttactgact
    19801 tcgtcagttt catctacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta
    19861 gtttattctt tgattttgag tattagattt actcaaaatc aaggattttg aagatgaact
    19921 tgtatcaaaa aatcgcggtt taaaatcgcg attttttata atttctcgtt aacaaagcgg
    19981 acaaactgat tccaccaaac ttttaagaag aaggcttttt caattttctt gtctgctacc
    20041 atttcgaaac tagggcgctc tgtggtgatg taaccttgac caatcaagtc cttgtcttca
    20101 taagtcaaat ggccaaccac tgttccagct tcaagtggtg ctgggattgc tttggaatca
    20161 ggtgtgaatt gaacagattg ggaagattga ttcccaacac gttcgattag atagatatcc
    20221 tctggagcca ctgcagttac tgtatcttct tttccatctt gtacaggggc tttgctatct
    20281 tgataggcat cgccttgttg aacgattttg cgaagtgtaa atgtagaaga aatataatcc
    20341 attagggaag atgtagctgt aaatcgagcg taaggattat tgtcttgatg atctgcattt
    20401 aaaacaactg tgatgactct catgcctttt tcgacagtag taccaacaaa agactctcca
    20461 gccttatctg ttgttcctgt ttttagccca tcaaaaccac cacggtaagc aggcatacct
    20521 tctaacatgt agttggttga agtgattgtc atcccagcaa aagtagaaga aggttttttg
    20581 gtgatttcta agacttgtgg gtattttttg atgaggttgc gagcaacgat agcgacatca
    20641 taagcactaa gcttattttc ctcatctttt ttagaacctg ggtaaatgtt atcccctaga
    20701 gtttcattgt taagacctgt cgtattgaca acagtggcat cctgaattcc ccattccaag
    20761 agttttgccc gcatcatatc gatgaaatct ttttctgagc cagcaatttt ctcagctagg
    20821 gcaatagcgg cgctgttggc actagatacc agagttgctt caagcaactc ttcgacagta
    20881 taattacggg cctccatagg aatattactg gcttcagaat ttgtcgtcaa ttgataagga
    20941 taatcagaaa tatctacagg agtggagagg gtaatacttc cgttttccaa agcttcatag
    21001 accagataag cagtaatcaa ttttgttatg gaagcaattt cgacaggttg cgttgcatcc
    21061 ttctcataga gaattttacc agtatttgcc tcaacagcaa tcgcatgttt agcggcaatg
    21121 gtaaaatctt gagcaacagc agtagaagca ccccctaaaa gagagacagt taacaaagtt
    21181 aaaaatattt ttttcatagt agtcttattc tatcataaag aaaaaaaata ttcttgcttt
    21241 aataattcat ctgttaagct ttttgaaaat atggtaaaat aaagtgaggg aggtaactca
    21301 tgtttcgtag aaataaatta tttttttgga ccacagaaat tttactctta accatcatct
    21361 tttacctatg gagacagatg gggtctttga ttaacccttt tgttagcgtg cttaatacaa
    21421 ttatgattcc atttttatta gggggctttc tttattattt gacaaaccct attgttactt
    21481 tcttaaataa agtctgtaaa ctcaatcgtt tgcttggtat tttaattacc ttgtgtactt
    21541 tggtctgggg aatggtcata ggtgttgtct atctcttacc tattttgatt aatcagttat
    21601 ctagtttgat tatatctagt caaactattt atagtcgagt acaagactta atcatagact
    21661 tatctaatta tcctgcgctc cagaatttgg atgtagaagc tacaattcag cagttaaact
    21721 tatcctatgt tgatattctt caaaatatcc taaatagcgt atcaaatagt gtggggagcg
    21781 tcttgtcagc tcttatcagt actgttttga ttttgattat gactccagtt tttttggttt
    21841 atttcttatt agatggacat aaattcttgc ccatgcttga aagaacgatt ctaaagaggg
    21901 atcgcttgca tattgcaggc ttattaaaga atttaaatgc gacgattgct cgctatatta
    21961 gtggagtttc gattgacgca atcattatag gttgtttggc ttatattggc tatagtatta
    22021 ttggtttaaa atatgcttta gtttttgcca ttttttctgg tgtagccaat ttaattcctt
    22081 atgtggggcc aagtattggt ttgattccta tgatcatcgc aaatatattc actgatcccc
    22141 atagactgct gattgcagtg atttatatgc ttgttgttca gcaggtagat ggcaatatct
    22201 tatatcctcg aatcgtagga agtgttatga aggttcatcc aatcacgatt ttagttttac
    22261 ttttgttgtc aagcaatatc tatggtgtag ttggaatgat tgtcgcagtg ccaacctatt
    22321 ctatcttgaa agaaatttct aagttcttat cccgtttgta tgaaaatcat aaaataatga
    22381 aagaacgaga aagagaatta gctaagtaaa agtcaggaga accctgattt ttctttactg
    22441 gaagtggcct ttagattaga agactgaaaa taagttaaag tcttaaacta attttcacag
    22501 ctaagaatag tagaagttaa tctgataaaa atcgaaaaaa ccagtggaat tctgtgtcag
    22561 ggtaagttcc actggttttc atagtctatt aaagttcgaa tgaaacctat ttatagtaga
    22621 ttgaaactag aatagtacac ctctaattct aaaacattgt tagaaatcga tttgactgtc
    22681 ctgatctatt cgttctattc ttatttcatt ttactatatt ttggtgcaat aagtgaaaag
    22741 tagtccgaat aatataagga ttgattttat agtttttaaa ctcaaatgaa ttgaaataaa
    22801 gagagtacga aaattctcat ctgaaagtat tttagaataa ttctcttcgt gaatttcttc
    22861 aaaacagata gcttcatctt aggtatgtga tttctttttg catttttgag ttagataagg
    22921 tataatggtt ttattgtctt ttggggtcgt tacggattcg acaggcatta tgaggcatat
    22981 tttgcgactc gtgtggcgac gtaaacgctc agttaaatat aactgcaaaa aataacactt
    23041 cttacgctct agctgcctaa aaaccagcag gcgtgacccg atttggattg ctcgtgttca
    23101 atgacaggtc ttattattag cgagatacga ttaagccttg tctagcggtt tgataagaga
    23161 ttgatagact cgcagtttct agacttgagt tatgtgtcga ggggctgtta aaataataca
    23221 taacctatgg ttgtagacaa atatgttggc aggtgtttgg acgtgggttc gactcccacc
    23281 ggctccatta ttcctttgca ttcttttgca ttccttggta aaacgttgtt aaatcaacgt
    23341 tttttatttt tatctttggt attcctttgc attcttttgc taaaaaggga gtcacaaaca
    23401 gaccctattt taaaaaaagg atagaaaaaa ggatacaaca tttgtcgcat cctaaaaata
    23461 atcttttttc cacggaagac atgggattcg aacccacgca cgctattaca cgcctaccgc
    23521 gtttccaaca cggcctctta agcctcttga gtaatcttcc aatacttact caaatagtct
    23581 accataaagg ctcttatctt gcaataaaaa ttctagaaat aagaaaaatg atagattttg
    23641 aaagaaaatg ataaaaaatg cttgacttca aaagaaagta tgatagaatg aatagtgtaa
    23701 acgataacag gaggtgattc ggtgttaaaa acagagcgga agcaactgat tttagaggag
    23761 ttaaatcaac atcatgtagt ttctctagaa aaattagtta gtttgctaga aacgtcagaa
    23821 tcaacggttc gaagagactt ggatgagttg gaagcggaaa acaagcttcg tcgtgtgcat
    23881 ggtggagcag aactccccca ctccttacag gaagaagaaa ccattcaaga aaaatctgtc
    23941 aaaaaccttc aagaaaagaa gttgctggct cagaaagcag cctctctcat taaagaaaaa
    24001 gatgtcatct ttatcgatgc tggaacaaca actgcttttt tgattcatga attggtcaat
    24061 aagaatatta cagttgtgac caactccatt caccatgccg ctcagttggt tgaaaagcag
    24121 attccaactg tcatggttgg aggaaacgtc aagacggcga cagatgctag tatcggtggc
    24181 gttgctctta accagattaa ccaattgcac tttgaccgtg cctttatcgg aatgaatggt
    24241 gttgacgatg gctattatac gactcctgat atggaggagg gagctgtgaa aagagctatt
    24301 ttggagaatg ccaagcagac ctacgtcttg gtggattcgt caaaaattgg acaaacttgc
    24361 tttgccaagg tagcaccact caaacgcgct atcgttatca ctagtcaagg gcatgagctc
    24421 ttgcaggtta ttaaggagaa aacggaggta atagaagtat gatttataca gtcacactca
    24481 atccatccat tgactatatc gttcgtttgg accaagtcaa agttggtagt gtaaatcgta
    24541 tggacagtga tgataagttt gctggtggga aaggaatcaa tgtcagccgt gtcttgaaac
    24601 gtttgaatat accaaataca gcgacgggat ttatcggtgg ctttactggt aaatttatca
    24661 cagatacttt agcagaggaa gaaatcgaga cacgttttgt ccaggtggca gaagatactc
    24721 gtatcaatgt taaaatcaaa gcagaccaag aaacagaaat caacggaacg ggtccaactg
    24781 ttgaatcggt tcagctagaa gaattgaaag ctattttatc tagtctgaca gcagaagata
    24841 cagttgtctt tgcaggttca agtgctaaaa atctaggcaa tgttatctat aaggatttga
    24901 tttccttgac gcgccagact ggtgcgcaag tggtctgtga ctttgaagga cagaccttaa
    24961 ttgatagttt ggactaccag cctcttcttg taaaaccaaa caatcatgaa cttggagcga
    25021 tttttggggt taaactcgaa agtttagatg aaattgagaa atacgctcgt gagttactgg
    25081 ctaagggtgc tcaaaatgtt attatctcta tggctggtga tggtgccctt cttgtcacat
    25141 ctgagggagc ttacttcgct aaaccaatca aaggaacagt caaaaattca gttggagctg
    25201 gtgattctat ggttgctgga ttcacaggtg aatttgtcaa atcaaaagac gtagtagaag
    25261 ccttcaaatg gggagtggct tgcggaacgg caactacctt ctcagatgac ttggcaacgg
    25321 cggaatttat taaagaaaca tatggaaaag ttgaggtaga aaaacgatga aaattcaaga
    25381 cctattgaga aaagatgtca tgttgctaga tttgcaggca actgaaaaaa cagctgtcat
    25441 cgacgagatg attaaaaatt tgacagacca cggttatgta acagattttg aaacatttaa
    25501 agaaggaatt ttggcgcgtg aagctttgac ttctactggt ttgggtgatg gaatcgcaat
    25561 gcctcacagc aaaaacgctg ctgtcaaaga agcgacagtt ctatttgcta agtcaaataa
    25621 gggtgttgac tacgagagct tggatggaca agcaactgac ctcttcttca tgattgcagc
    25681 tccagaaggt gccaatgata ctcacttggc agccttggca gaattgtctc aatacttgat
    25741 gaaagacggt tttgcagaca aacttcgtca agcaacatct gcagaccaag ttatcgaact
    25801 ttttgaccaa gcttcagaaa aaactgagga acttgttcaa gcacctgcta atgactctgg
    25861 tgactttatc gtagctgtta cagcttgtac aacaggtatt gcccacactt acatggccca
    25921 agaagccctt caaaaagtag ctgctgaaat gggggttggt atcaaggtcg aaaccaacgg
    25981 tgctagcggt gttggaaatc aactaactgc agaagatatc cgtaaggcta aagctattat
    26041 cattgcagca gacaaggccg ttgaaatgga tcgatttgat ggaaaaccat tgatcaatcg
    26101 tccagttgct gacggtatcc gtaagacaga agagctaatt aacttggctc tttcaggaga
    26161 tactgaagtc taccgtgccg ctaatggtgc caaagctgca acagcctcta acgaaaaaca
    26221 aagccttggt ggtgccttgt acaaacactt gatgagtggt gtatctcaaa tgttaccatt
    26281 cgttatcggt ggtggtatca tgattgccct tgccttcttg attgacggtg ctttgggtgt
    26341 tccaaatgaa aaccttggca atcttggttc ttaccatgag ttagcttcta tgttcatgaa
    26401 aattggtgga gctgcctttg gtttgatgct tccagtcttt gcgggttatg ttgcctactc
    26461 tattgctgaa aaaccgggtt tggtagcagg tttcgtggct ggtgctattg ccaaagaagg
    26521 ttttgccttt ggtaaaattc cttatgccgc aggtggtgaa gcaacttcaa ctcttgcagg
    26581 tgtctcatct ggtttcctag gtgcccttgt tggtggattt atcgcaggtg ccttggttct
    26641 tgccatcaag aaatacgtta aagttcctcg ttcactcgaa ggtgctaaat caatccttct
    26701 attgccactt cttggaacaa tcttgacagg atttgttatg ctagctgtga atatcccaat
    26761 ggctgcaatc aacactgcta tgaatgactt cctaggcggt cttggaggag gttcagctgt
    26821 ccttcttggt atcgtccttg gtggaatgat ggctgttgac atgggtggac cagttaataa
    26881 agcagcttat gtctttggta caggtacgct tgcagcaact gtttcttcag gtggttctgt
    26941 agccatggca gcagttatgg ctggaggaat ggtgccacca cttgcaatct ttgtcgcaac
    27001 tcttcttttc aaagataaat ttactaagga agaacgtaac tctggtttga caaacatcat
    27061 catgggcttg tcatttatca ctgagggagc gattccattt ggtgccgctg acccagctcg
    27121 tgcgattcca agcttcatcc ttggttcagc agtagcaggt ggactcgttg gtcttactgg
    27181 tatcaaactc atggcgccac acggaggaat cttcgttatc gcccttactt caaatgctct
    27241 cctttacctc gtttctgtct tggtaggagc aatcgtaagt ggtgtggttt atggttacct
    27301 acgcaaacca caagcataaa aaatagaaaa atgaaaagat tggaccgttt ggtgcagtct
    27361 ttttctcttc ccgaaatgcc tgtgaaatat ggtataatag aagaatggca aacaagaata
    27421 caagtacaac aagacggaga ccgtctaaag cagaactgga aagaaaagaa gcgattcaac
    27481 gaatgttgat ttcgttagga attgcgattt tattgatttt cgcagccttc aaattagggg
    27541 ctgcaggtat aaccctttat aatttaattc gcttgctagt gggtagccta gcttatctgg
    27601 cgatattcgg cctattaatc tatctcttct ttttcaagtg gatacgaaaa caggaaggac
    27661 tcttatctgg ctttttcacc atatttgctg gcttactctt gatttttgag gcctacttgg
    27721 tttggaaata tggtttggac aagtccgttc taaaagggac catggctcag gttgtgacag
    27781 atctgactgg ttttcgaacg actagctttg ctggaggggg cttgatcggg gtcgctcttt
    27841 atattccaac agcctttctc ttttcaaata tcggaactta ctttattggt tctatcttga
    27901 ttttagtggg ttctctccta gtcagccctt ggtctgttta cgatattgct gaatttttca
    27961 gtagaggctt tgccaaatgg tgggaagggc acgagcgtcg aaaagaggaa cgctttgtca
    28021 aacaagaaga aaaagctcgc caaaaggctg agaaagaggc tagattagaa caagaagaga
    28081 ctgaaaaagc cttactcgat ttgcctcctg ttgatatgga aacgggtgaa attctgacag
    28141 aggaagctgt tcaaaatctt ccacctattc cagaagaaaa gtgggtggaa ccagaaatca
    28201 tcctgcctca agctgaactt aaattccctg aacaggaaga tgactcagat gacgaagatg
    28261 ttcaggtcga tttttcagcc aaagaagccc ttgaatacaa acttccaagc ttacaactct
    28321 ttgcaccaga taaaccaaaa gatcagtcta aagagaagaa aattgtcaga gaaaatatca
    28381 aaatcttaga agcaaccttt gctagctttg gtattaaggt aacagttgaa cgggccgaaa
    28441 ttgggccatc agtgaccaag tatgaagtca agccggctgt tggtgtaagg gtcaaccgca
    28501 tttccaatct atcagatgac ctcgctctag ccttggctgc caaagatgtc cggattgaag
    28561 caccaatccc tgggaaatcc ctaatcggaa ttgaagtgcc caactccgat attgccactg
    28621 tatctttccg agaactatgg gaacaatcgc aaacgaaagc agaaaatttc ttggaaattc
    28681 ctttagggaa ggctgttaat ggaaccgcaa gagcttttga cctttctaaa atgccccact
    28741 tgctagttgc aggttcaacg ggttcaggga agtcagtagc agttaacggc attattgcta
    28801 gcattctcat gaaggcgaga ccagatcaag ttaaatttat gatggtcgat cccaagatgg
    28861 ttgagttatc tgtttacaat gatattcccc acctcttgat tccagtcgtg accaatccac
    28921 gcaaagccag caaggctctg caaaaggttg tggatgaaat ggaaaaccgt tatgaactct
    28981 ttgccaaggt gggagttcgg aatattgcag gttttaatgc caaggtagaa gagttcaatt
    29041 cccagtctga gtacaagcaa attccgctac cattcattgt cgtgattgtg gatgagttgg
    29101 ctgacctcat gatggtggcc agcaaggaag tggaagatgc tatcatccgt cttgggcaga
    29161 aggcgcgtgc tgcaggtatc cacatgattc ttgcaactca gcgtccatct gttgatgtca
    29221 tctctggttt gattaaggcc aatgttccat ctcgtgtagc atttgcggtt tcatcaggaa
    29281 cagactcccg tacgattttg gatgaaaatg gagcagaaaa acttcttggt cgaggagaca
    29341 tgctctttaa accgattgat gaaaatcatc cagttcgtct ccaaggctcc tttatctcgg
    29401 atgacgatgt tgagcgcatt gtgaacttca tcaagactca ggcagatgca gactacgatg
    29461 agagttttga tccaggtgag gtttctgaaa atgaaggaga attttcggat ggagatgctg
    29521 gtggtgatcc gctttttgaa gaagctaagt ctttggttat cgaaacacag aaagccagtg
    29581 cgtctatgat tcagcgtcgt ttatcagttg gatttaaccg tgcgacccgt ctcatggaag
    29641 aactggagat agcaggtgtc atcggtccag ctgaaggtac caaacctcga aaagtgttac
    29701 aacaataaaa aaatagcttc tttccaagtt tggagggaag ctattttagt ggctattgat
    29761 tgcttttatt ttctgaagtt ggcgcattgg actgtttttc gttttcagta gcaggtttac
    29821 ttgaagcagg agtagaagag tcctgagttg ctgttttctg atcttctttt ttctcttcct
    29881 tgacgctaga ttttggtgtt tcctcttgct gtgttttttc ttgactagtg ttagtctctt
    29941 tagttggact ggtgttttcc ttaggggatt ccttttggat ttctttgaca atggttgtcg
    30001 tctggcttgt cgtaggttct tttttaatat ttttgttatt atccaaggcg ttcataatcg
    30061 tgatacttgc ggtaatcaag ccaaggatac tagcgattgt agcaacggtt ttttgaaaga
    30121 ctgtaaagcc ttttttgatg tgttctgttt ttggttttga agttctacga tagttagaca
    30181 tacattctct cctttgatta tgatttatta tactctgttt ctttaaaaaa atcttaaaaa
    30241 aagagaaatt tccctttctt gtcgcaagct ccgtttcatg atacaataga ggaagtgatt
    30301 ttagaaagcg tgagaaacat gatttacttt gataattcag cgacgaccaa gccttatcct
    30361 gaagcccttg aaacctatat gcaggtcgct tcaaaaattt taggaaaccc atctagtctc
    30421 catcgtttgg gagaccaagc aacacgaatc ttagatgctt ctcgccaaca gattgcagat
    30481 ttaatcggta agaaaagcga tgaaatcttc tttacctcgg gtggaacaga aggggataac
    30541 tggcttatca agggtgtggc ctttgaaaaa gctcagtttg gcaagcacat cattgtttca
    30601 gccattgaac atccagcagt caaagagtca gccctctggt tgaaaagtca aggatttgaa
    30661 gtggattttg ctccagttga taagaaaggc ttggtcgatg ttgaggcgtt agcaggtttg
    30721 atacggcatg atacaatcct cgtttccatc atggctgtga acaatgaaat cggctctatc
    30781 caacctattg aggctatttc agaattcttg gcagacaagc cgactatttc cttccacgtt
    30841 gatgcggttc aggcgcttgc caaaattccg actgaaaagt atctgacaga acgggtggat
    30901 tgcgcgactt tctctagtca caagttccac ggggttcgag gtgttggctt tgtctatatc
    30961 aaatctggca agaagattac acctcttctt acaggtggtg gccaggagcg agattatcgt
    31021 tcgacaactg aaaatgtggc agggattgca gcgacagcca aggccctccg tttgtctatg
    31081 gaaaagctag atatctttag gagcaagact gggcagatga aggcagtgat tcgccaagct
    31141 cttctgaact atccggatat ttttgtcttt tcagatgagg aaaactttgc acctcatatt
    31201 ctgacttttg gaatcaaagg tgttcgaggt gaagtcatcg ttcacgcctt tgaagactat
    31261 gatattttca tctcaacaac ctcagcttgt tcatctaagg caggaaaacc agccggtacc
    31321 ttgattgcca tgggagtgga caaagataag gccaagtcag ctgtgcgtct tagcctagac
    31381 ttggaaaatg atatgagtca ggtcgagcag tttttgacca agttaaaatt gatttacaat
    31441 caaactagaa aagtaagata ggagcattca tgcagtattc agaaattatg attcgctacg
    31501 gagagttgtc aaccaagggt aaaaaccgta tgcgtttcat caataaactt cgtaataata
    31561 tttcggacgt tttgtctatc tatacccaag ttaaggtaac agcagatcgc gaccgtgccc
    31621 acgcttacct caatggagct gattacacag cagttgcaga atctctcaaa caagtttttg
    31681 gaattcaaaa cttttctcct gtttataagg ttgaaaaatc tgtagaagtt ttgaagtctt
    31741 ctgtccaaga gattatgcgg gacatctaca aggaaggtat gacctttaag atttctagca
    31801 agcgtagcga ccacaacttt gaacttgata gtcgtgaact caaccaaaca cttggagggg
    31861 ctgtattcga agccattcca aatgtgcaag ttcaaatgaa aagtcctgac atcaatcttc
    31921 aggtggagat tcgtgaagaa gcagcctatc tttcttatga aaccattcgt ggggctggtg
    31981 gtttgccagt tggaacttca ggtaaaggga tgctcatgtt gtcaggaggg attgactcac
    32041 ctgtagcagg ttatcttgct cttaagcgtg gggtggatat cgaggcagtt cactttgcta
    32101 gtccaccata tactagtcct ggtgccctca agaaagcgca ggacttgacc cgtaaattga
    32161 ccaagtttgg cggaaatatc cagtttatag aggtgccttt cacagagatt caagaggaaa
    32221 tcaaagccaa agcgccagaa gcttatttga tgactctaac tcgtcgcttt atgatgcgga
    32281 ttactgaccg tattcgtgag gtacgaaatg gtttggttat catcaatggg gaaagtctag
    32341 gtcaagtagc cagccaaacc cttgaaagta tgaaggctat caatgctgtt accaacactc
    32401 ccatcattcg tcctgtggtt accatggaca agttggaaat cattgacatc gcccaggaaa
    32461 tcgatacctt tgacatttca atccaaccgt ttgaagactg ttgtaccatt tttgcaccag
    32521 atcgtccaaa aacaaatcct aaaattaaga atgcggagca gtacgaagcg cgtatggatg
    32581 ttgaaggctt ggttgagcga gcagtggctg gaatcatgat tactgaaatc acacctcaag
    32641 ccgaaaaaga tgaagttgat gacttgattg acaatctgct ctaattcaga aaatccaaaa
    32701 gaatagcgaa aatcagtaaa aaaagttagt tttttctcta aaaacaggta aaaaactaac
    32761 tttttttatt tttatgatat aatgatataa aattttgaat atagagagtt ttctgacaat
    32821 gaatcaatcc tacttttatc taaaaatgaa agaacacaaa ctcaaggttc cttatacagg
    32881 taaggagcgc cgtgtacgta ttcttcttcc taaagattat gagaaagata cagaccgttc
    32941 ctatcctgtt gtatactttc atgacgggca aaatgttttt aatagcaaag agtctttcat
    33001 tggacattca tggaagatta tcccagctat caaacgaaat ccggatatca gtcgcatgat
    33061 tgtcgttgct attgacaatg atggtatggg gcggatgaat gagtatgcgg cttggaagtt
    33121 ccaagaatct cctatcccag ggcagcagtt tggtggtaag ggtgtggagt atgctgagtt
    33181 tgtcatggag gtggtcaagc cttttatcga tgagacctat cgtacaaaag cagactgcca
    33241 gcatacggct atgattggtt cctcactagg aggcaatatt acccagttta tcggtttgga
    33301 ataccaagac caaattggtt gcttgggcgt tttttcatct gcaaactggc tccaccaaga
    33361 agcctttaac cgctatttcg agtgccagaa actatcgcct gaccagcgca tcttcatcta
    33421 tgtaggaaca gaagaagcag atgatacaga caagaccttg atggatggca atatcaaaca
    33481 agcctatatc gactcgtcgc tttgctatta ccatgatttg atagcagggg gagtacatct
    33541 ggataatctt gtgctaaaag ttcagtctgg tgccatccat agtgaaatcc cttggtcaga
    33601 aaatctacca gattgtctga gattttttgc agaaaaatgg taagttaaga aaggaaaaaa
    33661 cgaaatgcat attgaacatc ttagccactg gagtggtcat cttaaccgtg aaatgtacct
    33721 taaccgttat ggacatggtg ggattccagt tgtggtcttt gcttcatcag gtggtagtca
    33781 caacgaatac tatgattttg gcatgattga tgcctgtgct tcctttatcg aggaaggcct
    33841 tgtccagttc tttaccctat ctagtttgga tagtgagagc tggttggcta cttggaaaaa
    33901 tgctcatgac caagcggaaa tgcaccgtgc ctacgaacgt tatgtgattg aggaggccat
    33961 tcttttatca agcacaagac aggttggttt gatggcatga tgacgacagg ttgctctatg
    34021 ggagcctatc atgcactcaa tttcttcctc cagcatccag atgtctttac caaagtgatt
    34081 gctctcagtg gtgtttacga cgcacgtttc tttgtcggtg attactacaa cgatgatgct
    34141 atttaccaaa actcgccagt agattatatt tggaaccaaa acgacggctg gtttattgac
    34201 cgttaccgtc aggcagagat tgtgctgtgt acggggcttg gagcctggga acaagatggt
    34261 ttgccatcct tttacaagct caaagaagcc tttgacaaga aacaaattcc agcctggttt
    34321 gctgaatggg gacatgatgt cgcccatgac tgggaatggt ggcgtaaaca aatgccttat
    34381 ttcctcggta atctctattt ataaaaggag ttacctatga attaccttgt tatttctccc
    34441 tactatccac aaaactttca acagtttacc atcgaactag ctaataaagg catcacagtc
    34501 ttgggaattg gtcaagagtc ttacgagcaa ttggatgagc ccttgcgcaa tagcttgacc
    34561 gagtattttc gtgttgataa tcttgagaac atagatgaag tcaaacgtgc agttgctttt
    34621 ctcttttata aacatggtcc aattggccgc atcgagtctc acaatgaata ctggcttgag
    34681 ctagacgcaa cactcagaga acaattcaat gtttttggtg ccaaaccaga ggatctcaaa
    34741 aagacgaaat ataagtctga aatgaagaaa cttttcaaaa aagcaggtgt tcctgtggta
    34801 cctggagctg ttatcaagac ggaagcagat gttgatcaag cagtgaaaga aatcggtctt
    34861 ccaatgattg ccaaacctga taatggagtg ggagcagccg caacctttaa acttgagaca
    34921 gaagacgata tcaatcactt caagcaagaa tgggaccatt caacccttta tttctttgaa
    34981 aaatttgtca cttccagcga aatctgtacc tttgacgggc tcgtggacaa ggatggaaag
    35041 attgtcttct caacaacctt tgactacgcc tatacaccgc ttgacctcat gatttataag
    35101 atggacaatt cttattatgt gctcaaggat atggatccta aactgcgcaa gtatggggaa
    35161 gcaattgtca aagaatttgg tatgaaagaa cggtttttcc atattgagtt cttccgtgag
    35221 ggggacgatt atattaccat cgagtacaat aaccgccctg caggtggttt taccattgat
    35281 gtttataact ttgctcattc cttggacctt tatcgtggct atgcagctat tgtcgcagga
    35341 gaggagttcc cggcgtcaga ctttgaaact cagtattgtt tggctacttc tcgccgtgca
    35401 aatgctcact atgtttattc agaagaggat ttgcttgcca aatatagcca gcagttcaag
    35461 gttaaaaaag tcatgccagc tgccttcgcg gaacttcaag gagattacct gtatatgctg
    35521 accactccga gtcgacaaga aatggagcag atgattgcag atttcggaca acgtcaagaa
    35581 taagaactat cggattaagg aaattaactc ccttaatcct tttgttttgt ctgataaaaa
    35641 ataagagcat cccaacaagg tagctatcat aaaacttgtt cgataactat ttgaagcagg
    35701 attaggtggt cagaaattaa attttaatat ttcaattgag tcatagtatt gtgtttgcgt
    35761 atccttaaat cagctaaaag gatccatgac gacacctata cgatatagtt ttcaagatac
    35821 caaacaagtc tattaatatt caatgaaaat caaagagcaa actaggaagc tagccgcagg
    35881 tttctcaaaa cactgttttg aggttgtgga tagaactgac agagtcagta tcatatacct
    35941 acggcaaggt gaagctgacg tggtttgaag agattttcga agagtataaa atattcaggt
    36001 gacgcataga tatagttaat tgaagctttg tttgaaatct gataaaataa tgatattact
    36061 aagttttaaa aactaaagaa aagggaagat atgattacag gcgaattaaa aaataaaatc
    36121 gatcagctgt gggaaattct ttggacagaa ggaaacgcaa atcctttaac aaatattgaa
    36181 cagttgactt atctcttatt tatgaaagat ttggatagtg tcgagcttgg acgtgaaagt
    36241 gatgctgaat ttctagggat tccttatgag ggagtttttc caaaagataa acctgaatac
    36301 cgttggtcaa cttttaaaaa tataggagat gctcaggaag tttatcgttt aatgactcag
    36361 gagatttttc cgtttattaa aaatctcaag ggggatacag atgatacagc cttttcacga
    36421 tatatgcgag aagctatttt tcaaataaat aaacctgcta cgcttcaaaa ggcaatttct
    36481 atcttagatg tttttccaac taggggatta gatgtagatt ttgataatga caaacaaagt
    36541 attactgata tcggagatat ctatgaatat ctgttatcaa aattgtcgac cgcaggtaaa
    36601 aatggacagt tccgtacacc tcgtcacatc atcgatatga tggttgagtt gatgcaaccg
    36661 actatcaaag atatcatctc agatcccgct atgggttctg ctggcttctt agtatctgct
    36721 agccgttact taaagcgtaa gaaagatgaa tgggaaacca atacagataa tatcaatcat
    36781 tttcataatc agatgtttca tggaaatgat acggatacga ctatgttgag acttggggcg
    36841 atgaacatga tgctacatgg agtagaaaat ccacaaatca gttaccttga ctcgctgtct
    36901 caagataatg aagaagccga taaatatact ttggttttag caaatcctcc ttttaagggc
    36961 tcacttgact acaattcaac ctctaatgac cttcttgcaa ccgtaaaaac caaaaaaaca
    37021 gaattactct ttctttctct tttcttgcga actttaaaac caggtggacg agcagcagtt
    37081 atcgtacctg atggtgtcct ttttggttcg tctaaagctc ataaaggaat tcgtcaggaa
    37141 attgtagaga atcataagct tgatgctgta atctcaatgc ctagtggtgt gttcaagcct
    37201 tatgctggag tttcaactgc cattctcatc tttacaaaaa ctggtaatgg tggtactgac
    37261 aaagtctggt tttacgatat gaaagcggat ggtttaagtt tggatgataa gcgacaaccg
    37321 attagcgaca atgatattcc agatattatc gaacgctttc atcatcttga aaaagaagca
    37381 gaacgtcaga gaacggatca atctttcttt gttccagttg ctgagataaa ggaaaatgat
    37441 tatgatttgt ctatcaataa atataaagag attgagtatg aaaaagttga gtatgaacca
    37501 acagaggtca tcttaaagaa aatcaatgat ttagaaaaag aaattcaagc tggcttggct
    37561 gaattagaaa aattactcaa gtagagaggt ggctgtatga aaaaagtgaa gttgggggaa
    37621 gtcttatctc taaaaaaagg caagaaagcc actgtacttg ctgaacaaac aactctaagc
    37681 caacgttata ttcaaataga tgatttaaga aataataata atttaaaatt cactgaaagt
    37741 ttaaatatga ctgaagcact cccagatgat attctgatag catgggatgg agctaatgca
    37801 ggaacagttg gttatggatt atcgggagct gttggtagta caattacggt cttaaaaaag
    37861 aatgagcgat acaaagaaaa aattatatca gattacttgg gagtcttttt ggaaagtaaa
    37921 tcgcagtatt tacgagaaca ttcaacaggt gcaacaattc ctcatttaaa caagaatata
    37981 ttacttgatt tacaattaga attgctaggt atcgaagaac aagagaacat tatctgtatt
    38041 cttaatacga ttaaaaggct tattactaaa agaaaattgc agttagatga actaaacttg
    38101 ctcgtcaaat cccgatttaa cgagatgttt ggggatgtta ttctaaatga aaaagaatgg
    38161 aaagttagca aatggaacga gattctaaca ataagaaatg gtaaaaatca aaaacaggtt
    38221 gaagatgctg atgggaaatt tcctatttat ggaagtgggg gaattatggg atatgctaaa
    38281 gattggatag tgaagaaaaa ttcagttatt attggacgta aaggaaatat aaataaacct
    38341 attttagtta gagaaaattt ttggaatgta gatacagcat ttggattaga gcctgtttta
    38401 gaaaaaataa actcagaata tttattctat ttttgtcaat tatacaattt tgagaagtta
    38461 aataaggctg taacaatacc tagtttaact aaatcagatt tattaaatat ttccatcccc
    38521 ctccccccac tagccctcca aaatgagttc gcagactttg tagccctggt cgacaaatca
    38581 caatttgctt gtgagatagc tataaaagtg tggagaaata gcttgaaatt tagtataata
    38641 tagctaaact atttgtttaa agtgagaaaa aaatgggaaa ttttagcttt cttttaaaaa
    38701 atgacgaata tgaatctttt tcaaaacctt gcattgaagc tgagaatatg attgctacat
    38761 caactgtggc tactgccttt atggcgcgtc gtgctttaga gcaggctgtc cattggatat
    38821 atagtcacga ttcatattta gaagctccct atcgtgctac tctatcttct ttagtatggg
    38881 atgatgattt tagggatatc gtagattctg aactccacaa gcagatagtt ctgttgattc
    38941 ggtggggaaa ccatgctgct catggtggtg aaattaagga acgagaagcg attttagctt
    39001 tgcatcattt gtatcagttt gttaatttta tcgattattg ttacagcaat gagtttgtgg
    39061 agcgttattt tgatgagaag tgcttaccac tttcagcaaa catcaaatac cgagaaactc
    39121 cacaatctat gataaagtta caagacagtt taccagaact gcctgatttt catgaacaga
    39181 tggctgctca gtccgtagaa gttcaagaga cttatactga aaaacgtgag actgcagcgc
    39241 aacggcaaga tgtgcctttc catattgatc aattatctga ggcagagaca agaaagctct
    39301 ttattgatat cgatctccgt ttagcaggat ggatatttga agaaaactgt cgtgttgaga
    39361 tagccgttga tggtctcaag cacggttcag gaattggtta ctgtgactat gtactttatg
    39421 gtaaaaatgg gaaaatttta gcgattgtgg aggctaaaaa agcctctgtc aatccagaag
    39481 taggggaagt acaggtcaaa gaatatgctg aagctttgga gaaacatatc ggctatcagc
    39541 caatttgctt tattacaaat gggttgaagc actatatact tgatggtccg aaccgccgcc
    39601 agattgcagg cttttactct caagaagaat tgcaattagt gatggataga cgtcatcttc
    39661 aaaaaccgct tgaggatatt tctagtaaaa ttagggacga tatttccggg cgtcactacc
    39721 aaaaacatgc cattgcaagc gtttgtgaag ctttctctga tcatcgtaga caggcacttt
    39781 tggttatggc aactggggcg gggaaaactc gtacagcagt ttctctagtt gatatcttat
    39841 cacgtcataa ctgggtaaaa aacgttctct tcttagccga tagaacttcc ttggttaagc
    39901 aagcatatga ttcgtttaga aaattactcc cagatctttc cgtttgtaac ttcttagaag
    39961 ataaagaagg agctcaatca agtcgaatgg tcttttcaac ttatccgacc atgattggag
    40021 cgattagtgg tcaagaagaa gtaaatcaac gcccttttac tgttgggcat tttgacctta
    40081 tcataattga cgaatctcac cgttctattt atcagaaata caagtccatt tttgattatt
    40141 ttgatgcaag gattgtaggc ttaacagcta ctccgcgtca agatttagat aaaaacacct
    40201 atggattctt taatttggag aatggggttc caacatatgc atatgatttg gaagaggctg
    40261 ttaaagacgg atatttagta gcctatcatt ctatcgaaac caaactgaaa ctacctacgg
    40321 atggtctaca ttatgatgat ttgtccgaag aagaaaagga acattttgat agcaaatttg
    40381 aagacgatag ctgtgaaaaa gatattgatg ggagtgtgtt taattccttt attttcaata
    40441 aaagtacagt agaaattgtt ttaaatgaac tcatgacaag aggaattcag acagcctcgg
    40501 gtgatgaaat tggtaaaact attatttttg ctaaaaatca tgaccatgcg gaatatatca
    40561 gaggtatttt taacaaccgc tatcctgaaa aagggagcga ctatgctcag gtgattgatt
    40621 atagtattaa gcattatcag accttgattg atgattttaa aattaaggag aagtatcctc
    40681 aaattgcgat ttctgtcgat atgttagata caggtattga tgtaccagag gttgttaatt
    40741 tagtcttctt caagaaagta cgctctaaaa ctaagttttg gcagatgatt ggtcgaggaa
    40801 cccgtctatg taaagattta tttggacctg agcaggataa ggaaaacttc ttggtatttg
    40861 attatgggga caattttgat tattttcgtg cagatccaag agatggagag ggtcgtcaca
    40921 ttgtttcgct gactcagcgt ttatttaata tcaaagtgga cttgattcga gaacttcagg
    40981 gactccaata ccaagaagat cagtttgcga gagcataccg tcagcagctt gtctcggaac
    41041 ttcaaggtcg tatagagagc ttaaatgagt tggacttcag ggttcgtatg gttttagata
    41101 cagtttatag ctataggaaa ttggaaagtt ggcagaatct aactgctgtt acaagtgaaa
    41161 ccattcaaaa aaatctctct ccgcttttat ttgatgaaga taaagaagat gagatggcga
    41221 ggagatttga tttgtggttg cttcatattc agttggggca actgacagct aaatcttcca
    41281 ctgttcatat ttcccaagtg atgaagacgg ctagagctct ttctgctatt ggcaatatcc
    41341 cgcaggtttt tgagcaggct gaaattatgg ctctttgtca actgtagtgg gttgaaaaaa
    41401 agctaagctt gagaaaggac aaattttgtc ctttcttttt tgatattcag ggcgataaaa
    41461 atccgttttt tgaagttttc aaagttccga aaaccaaagg cattgcgctt gataagtttg
    41521 atgagattat tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcgttgacg
    41581 attttctctt tgttctttag aaaggtttta aagacagtct gaaaaagagg atgaacctgc
    41641 ttcagattgt cctcaatgag tccgaaaaat ttctcagggt ctttgttctg aaagtgaaaa
    41701 agtaagagtt gatagatctg atagtggtgt ttcaagtctt ctgaatagct taaaatcttg
    41761 tcaagaattt ctttatttgt taagtgcatg cgaaaagtag ggcgataaaa acgtttatcg
    41821 ctcaatttac gactatcctg ttggatgagt ttccagtaac gcttgatagc cttgtattca
    41881 tgagattttc gttcaaactg attcataatt tgaacacgaa aacgactcat ggcacggctg
    41941 agatgttgga taatatggaa acgatctaga acgattttag cacacggaaa aagctgttta
    42001 gccaagtcat agtaaggact aaacatatcc atcgtaatga ttttcacttg acaacgaacg
    42061 gctctatcgt agcgaagaaa gtgatttcgg atgacagctt gtgttctgcc ttcaagaaca
    42121 gtgataatat taagattatc aaaatcttgc gcaatgaaac tcatctttcc cttagtgaag
    42181 gcatactcat cccaagacat aatctttgga agccgagaaa aatcatgctc aaagtgaaag
    42241 tcattgagct tgcgaatgac agttgaagtt gaaatggcca gctgatgggc aatatcagtc
    42301 atagaaattt tttcaattaa cttttgagca attttttggt tgatgatacg agggatttgg
    42361 tgatttttct ttaccagggg agtctcagca accatcattt ttgaacagtg atagcacttg
    42421 aaacggcg
//
LOCUS       DAVAZV010000012        40424 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVAZV010000012 DAVAZV010000000
VERSION     DAVAZV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.012"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            184..414
                     /gene="blpU"
                     /locus_tag="VQT46_000627"
     CDS             184..414
                     /gene="blpU"
                     /locus_tag="VQT46_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2370698.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1129..3282
                     /locus_tag="VQT46_000628"
     CDS             1129..3282
                     /locus_tag="VQT46_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET2370699.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGDMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            3295..4644
                     /locus_tag="VQT46_000629"
     CDS             3295..4644
                     /locus_tag="VQT46_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET2370700.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4815..5522
                     /locus_tag="VQT46_000630"
     CDS             4815..5522
                     /locus_tag="VQT46_000630"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET2370701.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIAGDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5724..9449
                     /locus_tag="VQT46_000631"
     CDS             5724..9449
                     /locus_tag="VQT46_000631"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET2370702.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQGTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVTKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9542..10984
                     /locus_tag="VQT46_000632"
     CDS             9542..10984
                     /locus_tag="VQT46_000632"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET2370703.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     RDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            11021..12043
                     /locus_tag="VQT46_000633"
     CDS             11021..12043
                     /locus_tag="VQT46_000633"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET2370704.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            12040..12585
                     /gene="purN"
                     /locus_tag="VQT46_000634"
     CDS             12040..12585
                     /gene="purN"
                     /locus_tag="VQT46_000634"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET2370705.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIALVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12669..13178
                     /locus_tag="VQT46_000635"
     CDS             12669..13178
                     /locus_tag="VQT46_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2370706.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            13203..14750
                     /gene="purH"
                     /locus_tag="VQT46_000636"
     CDS             13203..14750
                     /gene="purH"
                     /locus_tag="VQT46_000636"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET2370707.1"
                     /translation="MTKRVLISVSDKADIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDGVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYDDAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGENKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14872..16134
                     /gene="purD"
                     /locus_tag="VQT46_000637"
     CDS             14872..16134
                     /gene="purD"
                     /locus_tag="VQT46_000637"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET2370708.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVSETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFFEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLNYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16537..17025
                     /gene="purE"
                     /locus_tag="VQT46_000638"
     CDS             16537..17025
                     /gene="purE"
                     /locus_tag="VQT46_000638"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET2370709.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            17012..18103
                     /gene="purK"
                     /locus_tag="VQT46_000639"
     CDS             17012..18103
                     /gene="purK"
                     /locus_tag="VQT46_000639"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET2370710.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVDELGEGIDF"
     gene            18113..18340
                     /locus_tag="VQT46_000640"
     CDS             18113..18340
                     /locus_tag="VQT46_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET2370711.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            18403..19701
                     /gene="purB"
                     /locus_tag="VQT46_000641"
     CDS             18403..19701
                     /gene="purB"
                     /locus_tag="VQT46_000641"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET2370712.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19756..23694)
                     /gene="strH"
                     /locus_tag="VQT46_000642"
     CDS             complement(19756..23694)
                     /gene="strH"
                     /locus_tag="VQT46_000642"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2370713.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTPTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEDDKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKESARTVNLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGSMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQTLNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGG
                     FLKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVIEKKLPETGTHDSAGLVVAGLMATLAAYGLTKRKED"
     gene            complement(24009..24725)
                     /locus_tag="VQT46_000643"
     CDS             complement(24009..24725)
                     /locus_tag="VQT46_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2370714.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            25073..26860
                     /locus_tag="VQT46_000644"
     CDS             25073..26860
                     /locus_tag="VQT46_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET2370715.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPVYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26857..27333
                     /locus_tag="VQT46_000645"
     CDS             26857..27333
                     /locus_tag="VQT46_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2370716.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            27361..28266
                     /locus_tag="VQT46_000646"
     CDS             27361..28266
                     /locus_tag="VQT46_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2370717.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            28253..29068
                     /locus_tag="VQT46_000647"
     CDS             28253..29068
                     /locus_tag="VQT46_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2370718.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            29075..29479
                     /locus_tag="VQT46_000648"
     CDS             29075..29479
                     /locus_tag="VQT46_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2370719.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29778..30944
                     /locus_tag="VQT46_000649"
     CDS             29778..30944
                     /locus_tag="VQT46_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET2370720.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTTLLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVVLGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            31060..32097
                     /locus_tag="VQT46_000650"
     CDS             31060..32097
                     /locus_tag="VQT46_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET2370721.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGALLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            32305..33159
                     /locus_tag="VQT46_000651"
     CDS             32305..33159
                     /locus_tag="VQT46_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2370722.1"
                     /translation="MTYEYKSHIYLAETALNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREYYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTRIRLAR"
     gene            33309..33566
                     /locus_tag="VQT46_000652"
     CDS             33309..33566
                     /locus_tag="VQT46_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HET2370723.1"
                     /translation="MTNSKYITCLKRSEGQLCGIQKMIEGDRDCADIVTQLTAVRSSV
                     ERVIEMIITENLTECINQPLDDSEAQKERLEKAIRYLIKRK"
     gene            complement(33942..34034)
                     /locus_tag="VQT46_000653"
                     /pseudo
     CDS             complement(33942..34034)
                     /locus_tag="VQT46_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(34070..34366)
                     /locus_tag="VQT46_000654"
     CDS             complement(34070..34366)
                     /locus_tag="VQT46_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2370724.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(34356..34517)
                     /locus_tag="VQT46_000655"
     CDS             complement(34356..34517)
                     /locus_tag="VQT46_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HET2370725.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            34587..35351
                     /locus_tag="VQT46_000656"
     CDS             34587..35351
                     /locus_tag="VQT46_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET2370726.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLDEEI
                     DRYAREVGADCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            35964..37343
                     /locus_tag="VQT46_000657"
     CDS             35964..37343
                     /locus_tag="VQT46_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2370727.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            37357..38022
                     /locus_tag="VQT46_000658"
     CDS             37357..38022
                     /locus_tag="VQT46_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET2370728.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            38136..38231
                     /locus_tag="VQT46_000659"
                     /pseudo
     CDS             38136..38231
                     /locus_tag="VQT46_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            38377..38826
                     /locus_tag="VQT46_000660"
     CDS             38377..38826
                     /locus_tag="VQT46_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2370729.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVGILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKCHGGAVNRGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            38983..39393
                     /locus_tag="VQT46_000661"
     CDS             38983..39393
                     /locus_tag="VQT46_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET2370730.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            39509..>40424
                     /gene="pavB"
                     /locus_tag="VQT46_000662"
     CDS             39509..>40424
                     /gene="pavB"
                     /locus_tag="VQT46_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET2370731.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAV"
BASE COUNT        11184 a         7816 c         9457 g        11967 t
ORIGIN      
        1 gtaaaaaagt gattagaaaa catctttttt aaaaatagag atgattttga aacaaaaaag
       61 ctaattcaag acgtttcgat gccaattcaa gatttggatg aaaaaaatta atagatactg
      121 ttatactaaa cttgtcaagt ttgtaacaag acaaatatta aaaataaaaa agaggtattc
      181 gttatgaata caaaaaagat gtcacaattt gaaattatgg atactgagat gcttgcttgc
      241 gttgaaggtg gcggatgcaa ttggggagat tttgccaaag caggtgttgg aggaggagca
      301 gtacgaggtc ttcagctagg aattaaaaca agaacatggc aaggtgcagc aactggtgct
      361 gcgggaggag ctatacttgg aggtgtggcc tatgcagcga catgttggtg gtaattatgg
      421 attttaaaag ttttattatt ggtttagtag ttggtatatt tggtccttat atggatgatt
      481 taattagaaa aaaattttta aagtcttcgg agaagaaaac agaaaaatct gttaaaaaat
      541 aatcaaaact ataaatgatg aatctgaatc aaaattattt tgcgcatgta aagaggagtc
      601 ttatagtaac gagtcaaaaa aggagtaact atgaatcgta atttagaacg gtgttatcta
      661 ttctgactag gaatagatca taccagaggt agcttagaaa tagcagggac attagaaatt
      721 gaagtaataa ataggatgtc gtaagtgtta ctatcaatga tttatttgtt tcaagcttgc
      781 ctagggtgac agtaaaaaat caatttcctt tcaatagcat atttttagtg ggcaggactc
      841 ttgttctgcc tattttttta tccaaaaagt gcagttggga gggagatagg ctcatttggg
      901 aaggaagtcc agtttttgtt tagtgattgg ggtaagatag ttgttatcag atgagtttat
      961 actcttcgaa aatcaaattc aaaccacgtc aacgtcgcct tgccgtatat atgtgactga
     1021 cttcgtcagt cctatctaca acctcaaaac agtgttttga gcagcctgcg gctagtttcc
     1081 tagtttgctc tttgattttc attgagtatt agggaaaagg agatgaatat gaaatttggg
     1141 aaacgtcact atcgtccgca agtggatcag atggactgcg gtgtagcttc attagccatg
     1201 gtttttggct actatggtag ttattatttt ttggctcact tgcgagaatt ggctaagacg
     1261 accatggatg ggacgacggc tttgggcttg gtcaaggtgg cagaggagat tggttttgag
     1321 acgcgagcca ttaaggcgga tatgacgctt tttgacttgc cggatttgac ttttcctttt
     1381 gttgcccatg tgcttaagga agggaaattg ctccactact atgtggtgac tgggcaggat
     1441 aaggatagca ttcatattgc cgatccagat cccggggtga agttgactaa actgccacgt
     1501 gagcgttttg aggaagaatg gacaggagtg actcttttta tggcacctag tccagactat
     1561 aagccttata aggaacaaaa aaatggtctg ctctctttta tccctatatt agtgaagcag
     1621 cgtggcttga ttgccaatat cgttttggca acactcttgg taaccgggat taacattgtg
     1681 ggttcttatt atctgcagtc tatcattgat acctatgtgc cagatcagat gcgttcgaca
     1741 ctagggatta tttctattgg gctagtcatc gtctacatcc tccagcaaat cttgtcttac
     1801 gctcaggagt atctcttgct tgttttgggg caacgcttgt cgattgacgt gattttgtcc
     1861 tatatcaagc atgtttttca cctccctatg tccttctttg cgacacgcag gacaggggag
     1921 atcgtgtctc gttttacaga tgctaacagt atcatcgatg cgctggcttc gaccatcctt
     1981 tcgattttcc tagatgtgtc aacggttgtc attatttccc ttgttctatt ttcacaaaat
     2041 accaatctct ttttcatgac tttattggcg cttcctatct acacagtgat tatctttgcc
     2101 tttatgaagc cgtttgaaaa gatgaatcgg gataccatgg aagccaatgc ggttctgtct
     2161 tcttctatca ttgaggacat caacggtatt gagactatca agtccttgac cagtgaaagt
     2221 cagcgttacc aaaaaattga caaggaattt gtggattatc tgaagaaatc ctttacctat
     2281 agtcgagcag agagtcagca aaaggctctg aaaaaggttg cccatctctt gcttaatgtc
     2341 ggcattctct ggatgggggc tgttctggtc atggatggca agatgagttt ggggcagttg
     2401 attacctata ataccttgct ggtttacttt accaatcctt tggaaaatat catcaatctg
     2461 caaaccaagc ttcagacagc gcaggttgcc aataaccgtc taaatgaagt gtatctagta
     2521 gcttctgagt ttgaggagaa gaaaacagtt gaggatttga gcttgatgaa gggagatatg
     2581 accttcaagc aggttcatta caagtatggc tatggtcgag acgtcttgtc ggatatcaat
     2641 ttaaccgttc cccaagggtc taaggtggct tttgtgggga tttcagggtc aggtaagacg
     2701 actttggcca agatgatggt taatttttac gacccaagtc aaggggagat tagtctgggt
     2761 ggtgtcaatc tcaatcagat tgataaaaaa gccctgcgcc agtacatcaa ctatctgcct
     2821 caacagccct atgtctttaa cggaacgatt ttggagaatc ttcttttggg agccaaggag
     2881 gggacgacac aggaagatat cttacgggcg gtcgaattgg cagagattcg agaggatatc
     2941 gagcgcatgc cactgaatta tcagacagaa ttgacttcgg atggggcagg gatttcaggt
     3001 ggtcaacgtc agagaatcgc tttggcgcgt gctctcttga cagatgcgcc ggtcttgatt
     3061 ttggatgagg cgactagcag tttggatatt ttgacagaga agcggattgt cgataatctc
     3121 atggctttgg acaagacctt gattttcatt gctcaccgct tgactattgc tgagcggaca
     3181 gagaaggtgg ttgtcttgga tcagggcaag attgtcgaag aaggaaagca tgctgatttg
     3241 cttgcacagg gaggctttta cgcccatttg gtcaatagct agaaagagga gaggatgaaa
     3301 ccagaatttt tagaaagtgc ggagttttat aatcgtcgtt accataattt ttccagtagt
     3361 gtgattgtac ccatggccct tctgctcgtg tttttacttg gctttgcaac tgttgcagag
     3421 aaggagatga gtttgtccac tagagctact gtcgaaccca gtcgtatcct tgcaaatatc
     3481 cagtcaacta gcaacaatcg tattcttgtc aatcatttgg aagaaaataa gctggttaag
     3541 aagggggatc tcttggttca ataccaagaa ggggcagagg gtgtccaagc ggagtcctat
     3601 gccagtcagt tggacatgct aaaggatcaa aaaaagcaat tggagtatct gcaaaagagc
     3661 ctgcaagaag gggagaacca ctttccagag gaggataagt ttggctacca agccaccttt
     3721 cgcgactaca tcagtcaagc aggcagtctt agggctagta catcgcaaca aaatgagacc
     3781 atcgcgtccc agaatgcagc agctagccaa acccaagccg aaatcggcaa cctcatcagt
     3841 caaacagagg ctaaaattcg cgattaccag acagctaagt cagctatgga aacaggtgct
     3901 tccttggcca gtcagaatct agcctactct ctttaccagt cctacaagtc tcagggcgag
     3961 gaaaatcccc aaactaaggt tcaggcagtt gcacaggttg aagcacagat ttctcagtta
     4021 gaatctagtc ttgctactta ccgtgtccag tatgcaggtt caggtaccca gcaagcctat
     4081 gcgtcagggt taagcagtca attggaatcc cttaaatccc aacatttggc aaaggttggt
     4141 caggaattga cccttctagc ccagaaaatc ttggaggcag agtcaggtaa gaaggtacag
     4201 ggaaatcttt tagacaaggg gaaaattacg gcgagtgagg atggggtgct tcatcttaat
     4261 cctgagacca gtgattctag catggttgca gaaggtgccc tactagccca actttatcca
     4321 tctttggaaa gagaagggaa agccaaactc acagcctatc taagttcaaa agatgtagca
     4381 agaatcaagg tcggtgattc tgttcgctat actacgactc atgatgccgg gaatcaactt
     4441 ttcctagatt ctactattac aagtattgat gcgacagcta ctaagactga gaaagggaat
     4501 ttctttaaaa tcgaggcgga gactaatcta acttcggagc aggctgaaaa acttaggtac
     4561 ggggtggaag gccgcttgca gatgattacg ggcaagaaaa gttatctacg ttattatttg
     4621 gatcaatttt tgaacaaaga gtaatgttcg tgtttttaga gttaaataat ttttaaactg
     4681 tgagaaagat tcttcttgca gttttttctt tacaattttt aaaaaaacat ctgctattta
     4741 ttcggttaaa ttcttgtgtt ttttggtttt ttgtggtaaa atgtgctcaa gtaatacgaa
     4801 aggcgaactt taaaatgtca aaacaattga tctattcggg aaaagctaaa gatatctata
     4861 caactgagga tgaaaatctt attatttcaa cttacaagga ccaggcgact gctttcaacg
     4921 gtgtcaagaa ggagcagatt gcaggtaagg gagtcttgaa taatcagatc tcatctttta
     4981 tttttgagaa attaaatgcg gctggtgtgg cgactcactt tgtggagaaa ctttcagaca
     5041 cggaacaact caataaaaag gttaagatta ttcctttgga agtcgtgctc cgcaactata
     5101 ctgctggttc cttttcaaaa cgttttggtg tggatgaggg aatcgccttg gagactccga
     5161 ttgtcgaatt ttactacaaa aatgatgatt tggatgatcc atttatcaat gatgagcatg
     5221 tgaaattcct acagattgcg ggtgaccagc agattgccta cttgaaggaa gaaacgcgtc
     5281 gtatcaatga actattgaaa gtctggtttg ctgagattgg gcttaaattg attgacttta
     5341 agctagagtt cggttttgac aaggatggca agattatctt ggcagacgaa ttttcaccag
     5401 ataactgccg cttgtgggac gctgatggca accacatgga taaggatgtt ttccgtagag
     5461 gattgggaga actaaccgac gtttatgaga ttgtttggga aaagttgcag gaattgaaat
     5521 aatctgtttg caacggaaaa ccttcgtctc tcaactaaaa ggactcaggc tgaaaaggtc
     5581 ccccagacct tttcactctg tagagaacta ggtgaactaa cagatgttta cgaaattgtc
     5641 tgggaaaagt tgcagggttt aaaataacaa cctcaaggct gtttgggaat attgcaagag
     5701 ctgaaataaa ggaataagaa ttgatggata aacgtatttt tgttgaaaaa aaggctgatt
     5761 ttcaggtcaa gtcagagagt ttggttagag agctccagca caacttggga ctgtcaagct
     5821 tgaaaagtat tcgtattgtg caagtatatg atgtatttga cttggctgag gacttgtttg
     5881 cacctgcaga gaagcacatt ttctctgagc agggaaccga ccatgtttta gatgaagtat
     5941 ctgtgcaggc ggatcttgct aactatgctt tctttgccat tgaaagtctg ccagggcagt
     6001 ttgaccagcg tgcagcttcg tcacaggaag ccttgctttt gttgggaagt tcgagtgacg
     6061 tgacagtcaa cacagcccaa ctttacttgg tgaataaaga tattgatgcg actgagttgg
     6121 aagctgtcaa aaactacctg ctcaatccag ttgattctcg tttcaaggat atcacgacag
     6181 ggattgccaa gcaggagttt tcagagtcag acaagaccat tccaaaattg actttctttg
     6241 aaagctatac agcagaagac tttgctcgct acaaggccga gcaagggatg gccatggaag
     6301 tggatgattt gctctttatc caagactact ttaagtcaat cgggcgcgtg ccaactgaga
     6361 ctgaactcaa ggttttggac acttactggt ctgaccactg ccgtcatacg acttttgaga
     6421 cagagttgaa acacatcgac ttttcagctt ctaaatttca aaagcaattg cagtcaacct
     6481 atgacaagta tattgccatg cgcgaggagt taggtcggtc tgaaaaacca caaaccttga
     6541 tggatatggc gactattttc ggtcgttatg agcgtgctaa cggacgattg gatgatatgg
     6601 aagtctctga cgaaatcaat gcctgctcag ttgaaattga agtggatgtt gatggtgtca
     6661 aggaaccttg gctcctcatg tttaaaaatg aaacccacaa ccatccaaca gaaattgagc
     6721 catttggtgg agcggctacc tgtatcggtg gagctattcg tgatccgttg tcaggccgtt
     6781 cctatgttta ccaagccatg cgtatttcag gtgctggtga tattacagca ccgatttcgg
     6841 aaactcgtgc tgggaaattg ccacaacaag tcatttctaa aacagcagct catggttatt
     6901 cttcatatgg taaccagatt gggcttgcca caacctacgt tcgtgaatac ttccacccag
     6961 gctttgtagc taaacgtatg gaacttggtg ccgttgttgg tgcggctccc aagggcaatg
     7021 ttgtccgtga aaaacctgaa gcaggtgatg tgatcatcct tctcggaggc aaaacaggtc
     7081 gtgatggtgt cggtggtgcg acgggctctt ctaaggttca aacagttgag tctgtagaga
     7141 ctgctggtgc tgaggttcaa aaaggaaatg ccatcgaaga acgcaagatt cagcgcctct
     7201 tccgtaatgg caatgtcact cgtctgatca agaagtccaa tgactttggg gcaggcggcg
     7261 tctgtgtggc tatcggtgaa ttggcagacg gtcttgaaat cgacctcaac aaggtgcctc
     7321 ttaaatacca gggcttgaat ggtacagaaa ttgccatctc tgaatcacaa gaacggatgg
     7381 cggtcgtggt tcgtcctgaa gatgtggata ccttcgttgc cgaatgtaac aaagaaaata
     7441 ttgatgctgt tgtggtggcg acagtaactg aaaaaccaaa tcttgtcatg cactggaatg
     7501 gtgagacaat cgttgacttg gagcgtcgtt tccttgacac caatggtgtg cgcgtggttg
     7561 tcgatgccaa agttgtggac aaggatgtca aactcccaga agagcgtcaa acatctgctg
     7621 aaacactgga atcagatacc cttacggttc tatctgacct caaccatgca agtcaaaaag
     7681 gattacagac tatctttgac tgctctgttg gacgctcaac ggttaatcac ccacttggtg
     7741 gtcgttacca actcacacca actgaggcat ctgtgcagaa attgccagtt caacacggtg
     7801 tgactcatac tgcgtcggtc attgctcaag gtttcaaccc atatgtagct gaatggtctc
     7861 cataccacgg tgctgcttat gcggttatcg aagcaactgc tcgtttggtg gctgctggtg
     7921 ccaactggtc taaggctcgt ttctcttacc aagaatattt cgagcggatg gacaagcaag
     7981 cagagcgttt cggtcagcca gtagctgctc ttctaggttc tattgaagca caaattcagc
     8041 ttggcttgcc atctatcggt ggtaaggact ccatgtctgg tacctttgaa gaattgaccg
     8101 ttccgccaac cttggttgcc tttggggtga cgacggcaga tagccgtaag gtgctctctc
     8161 cagaatttaa agctgttggg gaaaatatct actacatccc aggtcaagcc ctctctgcag
     8221 agattgattt tgacttgatt aagaaaaatt ttgctcagtt tgaagcaagc caagctgacc
     8281 ataaagtgac gtctgcatca gctgtcaaat acggtggtgt agttgaaagt ttggctcttg
     8341 ctacctttgg aaactatatt ggtgcagagg tgaccttgcc tgaacttaaa acagctttga
     8401 cagctcaatt aggcggcttt gtcttcacat ctcctgaaga aattgctgga gtagagaaga
     8461 ttggacaaac gaaagcagac tttacactga ctgtcaacgg tgtgaagcta gatggacaca
     8521 agcttgacag tgcatttcaa gggacattgg aagaagttta cccaacagaa tttacccaag
     8581 cgaaagaact agaagaagta ccagctgtgg catcagatgt tgtgattaaa gccaaagaaa
     8641 aggttgaaaa acctgtggtt tacatcccag tctttccagg aaccaactca gaatatgatt
     8701 cagctaaggc cttcgaaaaa gaaggtgcag aggtcaattt ggtgccattc gtgaccttga
     8761 atgaagaagc tattgtcaag tcagttgaaa ctatggttga caatatcgac aagactaata
     8821 ttctcttctt tgccggtgga ttctcggctg cggatgaacc agatggttca gctaagttta
     8881 tcgtcaatat cctgcttaat gaaaaagtgc gtgtggctat tgatagcttt atcgcccgtg
     8941 gtggcttgat tatcggtatt tgtaatggat tccaagcctt agtcaaatcg ggtctcctac
     9001 catacggaaa ctttgaagat gctaacagta ctagtccaac cctcttctac aatgatgcca
     9061 accaacacgt gaccaagatg gtggaaactc gcattgccaa taccaactca ccatggttgg
     9121 ctggtgtgca agtgggcgat atccacgcta ttcctgtttc gcacggtgaa gggaagtttg
     9181 tcgtgacggc tgaggaattt gcagagctcc gtgacaatgg acaaattttc agccaatacg
     9241 ttgactttaa cggtaaacca agtatggatt ctaagtacaa tccgaatggt tctgtccatg
     9301 ccatcgaagg aattaccagc aagaatggtc aaatcatcgg taagatgggc cactcagaac
     9361 gttatgagga tggtcttttc caaaatatcc caggcaataa agaccaacac ctgttcgcat
     9421 cagcggttaa acatttcact ggaaaataag acttacagat tttctaatag atagtatcag
     9481 taatgtaaaa gtcatgtaaa tctagctctt gatgattaca aatgaaaatt aggtataaaa
     9541 aatgacatac gaagtaaaat ctcttaatga agaatgtggt gttttcggta tttggggaca
     9601 tccagatgct gctaagttga cctattttgg actccacagt cttcaacacc gtggtcagga
     9661 gggggcagga atcctctcca atgatcaagg acaactgaag cgccatcgtg acatggggct
     9721 tttatcagaa gttttcagaa atccagccaa tttggataaa ttgacaggag ctggtgcgat
     9781 tgggcatgtg cgttatgcga ctgctggcga agcttctgtt gataacatcc agcccttcct
     9841 cttccgtttt cacgatatgc agtttggctt ggctcataat ggaaatctga ccaatgcagc
     9901 ctctctcaag aaagaactgg aacaaagagg agcaattttc agcgcgactt cggactctga
     9961 aatcttggct cacctcattc gtcgtagtca taatcctagc ctgatgggca aaatcaagga
    10021 agcgctcagc cttgtcaaag gtggttttgc ctatatcttg ctgtttgagg acaagttgat
    10081 tgcggctctt gaccctaatg gctttcgtcc gctttctatc gggaaaatgg ccaacggagc
    10141 ggtggttgtt tcctctgaaa cctgtgcttt tgaggtcatt ggtgccgagt ggattcgtga
    10201 tttgaagcca ggtgagattg tgatcattga tgacgagggc attcagtatg acagctatac
    10261 agatgatact cagttggcga tttgttctat ggagtatatc tactttgctc gccctgattc
    10321 taatatccac ggtgtcaatg tccatacggc acgtaagaga atgggagcgc aattggcgcg
    10381 agaatttaag catgaggcag atattgtagt tggtgtgccc aattcttccc taagcgcggc
    10441 tatgggattt gcggaagaat caggcttacc aaatgaaatg ggtctgatca aaaaccaata
    10501 cacccagcga acttttatcc aaccgactca agaattgcgg gagcaaggag tgcggatgaa
    10561 actgtctgct gtttcgggtg ttgtcaaagg caaacgtgtg gtcatggtgg atgattccat
    10621 tgtacgtgga acaacctctc gtcgtatcgt tcagctcttg aaagaagcgg gtgcgactga
    10681 ggttcacgtt gccattggaa gtcctgcact agcgtatcca tgtttctacg ggattgatat
    10741 ccagacccgt caggagctga ttgcagccaa tcatacggtc gaagaaactc gccaaatcat
    10801 tggtgcggac agtctgactt atctttcaat tgatggcttg attgagtcga ttggtatcga
    10861 aacagatgcg ccgaacggtg gtctctgtgt cgcttacttt gacggtgact acccaacgcc
    10921 tctctatgac tacgaagaag actatcgtag aagtttggaa gaaaagacca gtttttacaa
    10981 gtaggcgaca gattctccat taaagaaaag gaaaaaacaa atgacaaata aaaatgcata
    11041 tgcccagtcg ggtgtggatg ttgaagcggg ttatgaagtt gttgaacgga ttaaaaagca
    11101 cgtggcccgt acggagcgtg caggtgtcat gggagctctt ggtggctttg gtggtatgtt
    11161 tgacctttcc aagactgggg ttaaagaacc cgtcttgatt tcagggactg acggtgtcgg
    11221 aaccaagctc atgttggcta tcaagtacga caagcacgat accatcgggc aggactgtgt
    11281 ggccatgtgt gtcaacgaca tcattgctgc aggtgcggaa cccctctatt ttctcgacta
    11341 cgtagcgaca gggaagaatg aaccagctaa gctagaacaa gtggttgctg gtgtggcaga
    11401 aggttgtgtg caggctggtg ctgccctcat cggtggggaa acggctgaaa tgccgggcat
    11461 gtacggcgaa gacgactatg acttggctgg ttttgcggtc ggtgtggctg aaaaatctca
    11521 aatcattgac ggttcaaagg tggtagaggg agatgttctt ctcggacttg cttcaagtgg
    11581 gattcactca aatggttact ctttggttcg tcgtgtcttt gcggattaca caggtgagga
    11641 agtcctacca gaattggaag gcaagaaact taaggaagtt ctacttgagc cgactcgtat
    11701 ctatgtcaag gctgtcttgc cgctcatcaa agaagagttg gtcaacggca ttgcccacat
    11761 cacaggtggt ggctttatcg aaaatgtccc tcgtatgttt gcagatgacc tagctgctga
    11821 aattgatgaa agcaaagttc cagtgcttcc aattttcaaa gcccttgaaa aatatggtca
    11881 gattaaacac gaagaaatgt ttgaaatctt caatatgggt gtgggactta tgttggcggt
    11941 cagccctgaa aatgtagagc gtgtaaaaga attgttggat gaagcagtct atgaaattgg
    12001 tcgcatcgtc aagaaagaaa acgaaagtgt cattatcaaa tgaaaaaaat agcggttttt
    12061 gcctctggta atggctcaaa ttttcaggtg attgccgaag aatttccagt ggagtttgtc
    12121 ttttcagacc atcgtgatgc ctatgtgctt gagcgtgcaa agcagctcgg cgttctgtcc
    12181 tatgcttttg aactcaagga gtttgagagc aaggcagact acgaagcagc ccttgtcgaa
    12241 ctcttggaag aacaccagat tgccttggtt tgcctagcag gctacatgaa aatcgttgga
    12301 ccaaccttat tgtcggctta tgaaggtcgg attgtcaaca ttcatccagc ctacttgcca
    12361 gaatttccag gagctcatgg gattgaggat gcttggaatg ctggcgtggg tcagtctggt
    12421 gtgaccattc actgggtgga ttcgggtgtg gatacaggcc aggtcatcaa acaggttcgt
    12481 gtgccacgac tagctgatga taccattgac agatttgaag ctcgcatcca tgaagcagag
    12541 tacaggttgt atccggaagt agtgaaggct ctatttacag attgactttt tgatgattca
    12601 tatgatatct ttgattttaa attggagtca gtgtttgttg aagacggctt caaacggagg
    12661 tatttgtaat gttagaatct aaaaaaacaa ctcgatatgt attttatgtc tatctgatgt
    12721 tattaacttg gggaatctta tttaagtttg aaacaaatcc tgaatttata gcatttttct
    12781 tagctccaag gtatatcaat tggattccat tttcagaacc actaatagtc gatggaaaaa
    12841 ttgtttttgc tgaaatgtta tttaatctga ttttctttat tccattaggt gtttgtttcc
    12901 ctttgataaa aactaattta tctagtttaa gaatagtcgg gacaggtttc ttgattagtt
    12961 tattgtttga gtgcttacag tatattttag caataggtat aacagatata acggatttga
    13021 ctttaaatac gctaggtgtc tgtgtaggct tactgattta tcaaattttt ataagagtgt
    13081 tcaaatcaca gactagaaaa tggatcaata tcttaggtat gcttagcctt ggttttgctt
    13141 atcttgtttt actgttactg catttaattg gtgtttaact aatgattaaa aaggagaata
    13201 taatgactaa acgcgtctta atcagcgtct cagacaaagc ggacattgtt gaatttgccc
    13261 aagaactcaa aaaacttggt tgggagatta tctcgacagg tggaactaag gttgcccttg
    13321 ataatgctgg ggtggatacc attgctatcg atggtgtgac tggtttccca gaaatgatgg
    13381 acggtcgtgt gaagaccctc cacccaaata tccacggagg gcttctcgct cgtcgtgact
    13441 tggatagcca cttggaagcg gctaaggaca acaagattga gctcattgac cttgtggtgg
    13501 tcaaccttta cccatttaag gaaactatcc ttaaaccaga tgtgacttat gatgatgcag
    13561 ttgaaaatat cgatattggt gggccatcta tgcttcgttc agcagcgaaa aatcatgcca
    13621 gtgttacagt tgtggtagat cctgctgact acgctgtggt tttggacgaa ttggcagcaa
    13681 acggcgaaac ctcttatgaa actcgccaac gtttagcagc caaagtattt cgtcacacag
    13741 cggcttatga cgccttgatt gcagaatact tcacagctca agtgggtgaa aacaagcctg
    13801 aaaaactcac tttgacttat gacctcaagc aaccaatgcg ttacggtgag aatcctcaac
    13861 aagacgcgga cttttaccag aaagctttgc ctacagacta ctccattgct tcagccaaac
    13921 agctcaacgg gaaagaattg tcatttaata atatccgtga tgcagatgct gctatccgta
    13981 tcatccgtga cttcaaagat agtccaaccg ttgtggctct caaacacatg aatccatgtg
    14041 gaattggtca agctgatgac atcgagactg cttgggacta cgcttatgag tctgacccag
    14101 tgtctatctt tggtgggatt gtcgtcctca accgtgaggt ggatgctgcg acagctgaga
    14161 agatgcacgg cgttttcctc gaaatcatca ttgcaccaag ctatacggat gaagcgctag
    14221 ccattttgat caataaaaag aaaaacttgc gtatccttgc cttgccattt aatgctcaag
    14281 aggctagcga agtggaagca gaatacacag gtgtagtcgg tggacttctc gtgcaaaatc
    14341 aagacgtggt caaggaaagc ccagctgact ggcaagtggt gactaaacgt cagccaactg
    14401 agacagaagc gactgctctt gagttcgctt ggaaggctat caagtacgtc aaatcaaatg
    14461 gtattatcgt gaccaacgac cacatgacac ttggtgttgg tccaggtcaa accaaccgtg
    14521 tggcttctgt tcgccttgcc attgaccaag ccaaagatcg tctggacggg gcggtccttg
    14581 cttcagatgc cttcttccca tttgcggata acgtggaaga aatcgccaaa gcaggaatta
    14641 aggccatcat ccagcctggt ggctctgtcc gtgaccaaga atccatcgaa gcagcggata
    14701 aatacggctt gactatggtc tttacaggtg tgagacattt tagacattaa gaagataaaa
    14761 gggaagaaaa cagtttcttt ccttttttgg cttaaaatgc taactgaaac aagattaaaa
    14821 cgaacttttt tgatataatg ttggtaaata attcgcaaaa gaggttgagg aatgaaactg
    14881 cttgttgtcg gttctggtgg tcgtgagcat gcgattgcta aaaagttact tgaatcaaaa
    14941 gacgtggaaa aagtctttgt agctcctggg aatgatggga tgactctgga tggtttggaa
    15001 ttggtaaata tctctatttc cgaacattct aaattgattg acttcgcaaa gaccaatgat
    15061 gttgcttgga cctttatcgg tccagatgat gcccttgctg ctggtatcgt ggatgatttt
    15121 aaccaagctg ggcttaaggc ctttggtccg actagggctg cagcggagct ggagtggtcc
    15181 aaggattttg ccaaggaaat catggtcaaa tatggtgttt cgacagcagc ctatggcaca
    15241 ttttcagatt tcgaggaagc aaaggcctat atcgaaaagc atggtgcgcc tatcgtagtc
    15301 aaggcggatg gcttggcgct tgggaagggt gtcgtcgttt ctgagacggt tgagcaagcg
    15361 gtcgaagccg ctcatgagat gcttttggac aataaatttg gtgactcagg tgcgcgcgtg
    15421 gttattgagg aattctttga aggagaggaa ttttcactct ttgcctttgt caatggtgat
    15481 aagttctaca tcatgccaac ggctcaggac cacaaacgtg cctatgatgg cgacaaaggg
    15541 cctaacacgg gtggtatggg tgcctatgcg ccagttccac acttaccaca gagtgtagtt
    15601 gatacagcgg ttgacaccat tgtcaagcca gttctagaag ggatgattaa agaaggtcgc
    15661 ccttatctgg gagttcttta cgcagggctt atcctgacag ctgatggacc gaaagtcatt
    15721 gagttcaacg ctcggttcgg agatccagaa actcagatta tcttgcctcg cttaacctct
    15781 gactttgctc aaaatatcac agatatcctg gatagcaagg agccaaatat cacgtggacg
    15841 gacaagggtg tgactctggg tgtggttgtc gcatccaagg gctacccgct aaattattca
    15901 aagggtgttg agttgccagt caaaaccgat ggcgacatca ttacctacta tgcaggggct
    15961 aagtttgcgg aaaatagcag agcactgctc tcaaacggcg gacgagttta tatgctcgtt
    16021 accacagcag ataccgtcaa agaagcccaa gccagcatct accaagaact atcccaacaa
    16081 aaaatagaag gactcttcta ccgaacagat atcggaagca aggcaattaa gtaaagatat
    16141 aagaataacg cgccgtagtc gccaaacacg ataatggtcg tcgtggtgaa aagaccagaa
    16201 cagtgaatgt tctggtcagg gggaaacttg gagaccgtag gctcaaagtt taggaatgaa
    16261 accgaaggtt tgcttccgcc tccatcacct aagaccatta tcaaaaagaa aaataaaaat
    16321 tcacaaaata cgttaatgat cgtatggttt gcgagcgtta gcgagctaat atagaacaat
    16381 caccgccgtt gtgaaagaac gattggatga taatccaatc gttcagggaa attggaagac
    16441 cttgggtttc caatttaggc atgagacacc tttggtggct gctgccgtcc ctcacaagct
    16501 aaggtgattg ttgaaaaaga ggaaaaagga gaagaaatga aaccagtaat ttccatcatc
    16561 atgggctcaa aatccgactg ggcaaccatg caaaaaacag cagaagtcct agaccgcttc
    16621 ggtgtagcct acgaaaagaa agttgtttcc gcacaccgca caccagacct catgttcaaa
    16681 catgcagaag aagcccgtag tcgtggcatc aagatcatca tcgcaggtgc tggtggcgca
    16741 gcgcatttgc caggcatggt agctgccaaa acaacccttc cagtcattgg tgtgccagtc
    16801 aagtctcgtg ctcttagtgg agtggattca ctctattcta tcgttcagat gccgggtggg
    16861 gtgcctgttg cgaccatggc tatcggtgaa gctggagcga ctaacgcagc tctctttgcc
    16921 ctccgtctcc tctctgtaga agataagtcc attgcggatg cacttgccaa ctttgctgaa
    16981 gaacaaggaa aaatcgcaga ggagtcgtca aatgagctca tctaaaacaa tcggaattat
    17041 cggtggcggt caactgggtc agatgatggc catttctgct atctacatgg gccacaaggt
    17101 tatcgcgctg gatcctgcgg cggattgccc ggcctctcgc gtggcggaaa tcattgtggc
    17161 accttataac gatgtggacg ccctccgtca gttggcagac cgttgcgatg tcctcactta
    17221 tgagtttgaa aatgtcgacg ctgacggttt ggatgccgtt atcaaggatg gacaactccc
    17281 tcaaggaaca gatctgctcc gcatttcgca aaatcgtatt tttgaaaagg actttttgtc
    17341 aaacaaggct caagtcactg tggcacccta caaggtcgtg acttctagcc tagacttggc
    17401 agatatcgac ttgtcgaaaa actatgtcct caagactgcg actggtggct acgatggtca
    17461 tggacaaaag gttattcgtt cagaagcaga cttggaagca gcctatgcgc tagcagactc
    17521 agcagactgc gtcttggaag aatttgtcaa ctttgacctt gagatttctg tcatcgtgtc
    17581 aggaaatggc aaggaggtga cgtttttccc agttcaggaa aatatccacc gcaacaatat
    17641 cctgtctaag accatcgtac cagcccgcat ttctgaaagt ctagcagaca aggctaaagc
    17701 tatggcagtg cgaatcgcag aacaactcaa cttgtctgga actctctgtg tggaaatgtt
    17761 tgcgactgat gatgacgtta ttgtcaatga aatcgcccca cgaccacata actctgggca
    17821 ctattctatt gaagcctgtg atttctctca gtttgacacc catattctgg gtgttctcgg
    17881 agcaccatta ccagtcatca aactccatgc gccagccgtt atgcttaatg tcctcggtca
    17941 gcatgtcgag gctgctgagc aatatgtgac agaaaattca agcgcccacc tccacatgta
    18001 tggtaaaata gaagcgaagc acaaccgcaa gatgggacat gtgaccttgt ttagtgatgt
    18061 accggatagt gtggatgagc ttggggaagg gattgatttt taggacaagt ctatgataca
    18121 aattatcgtt aatacattta ttgaaaagga taagactgga gcagttgttg aagtgttgta
    18181 tgccagtgct gaccaagata aggtacaagc taaatatgaa gaactagctg cacaataccc
    18241 cgaaaattat ttagctatct atgatgtacc gctggatacg gatttgaata cactagatca
    18301 ttacccgtct gtgtttattg aaaaagagga gtttgagtag aaatcttggt ttacctagat
    18361 agcttattcc caacagctta agaagaaagg aaaaattaac acatgatcaa ccgttactct
    18421 cgccctgaga tggcgaatat ttggagtgaa gaaaataaat accgtgcttg gcttgaggtg
    18481 gaaatcctct ctgacgaggc atgggctgag ttgggggaaa tccctaagga agatgtggct
    18541 ttgattcgca agaaggcgga ctttgacatc gaccgtattt tggaaattga gcaggagacg
    18601 cgccacgatg tggtggcttt cacgcgtgcg gtttctgaga ctcttggtga agagcgcaag
    18661 tgggttcact atgggttaac ttctaccgac gtggtggata ctgcttatgg ttacctctac
    18721 aagcaggcca acgacatcat ccgtcgtgac cttgaaaact tcactaatat catcgctgac
    18781 aaggccaagg agcacaagtt caccatcatg atggggcgta ctcatggtgt gcacgctgag
    18841 ccgacaacct ttggtcttaa attggcaact tggtacagcg aaatgaaacg caatatcgag
    18901 cgtttcgagc atgcagctgc tggtgtagaa gctggtaaga tttctggtgc ggttgggaac
    18961 tttgccaata tcccaccatt tgtagaggag tatgtctgcg ataaacttgg catccgtgcc
    19021 caagaaatct ctacacaagt ccttcctcgt gaccttcacg ctgagtactt tgcggttctt
    19081 gccagcattg cgacttcaat cgaacgtatg gcgactgaga ttcgtggtct acaaaaatct
    19141 gagcaacgcg aagtagaaga gttctttgct aaagggcaaa aagggtcttc agcaatgcct
    19201 cacaaacgca acccaatcgg ttctgaaaat atgactggtc tggcgcgtgt cattcgtggt
    19261 cacatgatta cggcttatga aaacgtcgct ctctggcacg aacgcgatat ttctcactca
    19321 tcagctgagc gtatcatcac accagatacg accattttga ttgactacat gctcaaccgt
    19381 tttggaaata tcgtcaagaa cttgacagtc ttcccagaaa atatgatccg aaacatgaac
    19441 tcgacttttg gtcttatctt tagccaacgg gctatgttga cattgattga aaaaggcatg
    19501 acccgtgagc aagcctatga cttggtgcaa ccaaaaacag cctactcttg ggacaaccaa
    19561 gtagacttta aaccacttct tgaggcagat tcagaagtaa catcacgtct cactcaagaa
    19621 gaaatcgatg aaatcttcaa cccagtttat tacaccaaac gagtggatga tatctttgaa
    19681 cgtcttggac taggtgatta attaaaaaat aaacagcgag cttcaatctc gctgtttatt
    19741 ttttatcgaa aagacttagt cttcttttct tttagtgagt ccataggctg ctagtgtggc
    19801 catgagtcct gcgactacta gtcctgcaga atcgtgagtt cctgtttcag gaagtttttt
    19861 ctctattacc acaggagctg gatcttgagg aagagctttg ctttcctcag caggagcagt
    19921 tgatggagct ggttggcttg ggatttctag ttttggtttt tcttcagcaa tagcggcttg
    19981 tccgttttca tcgcctacat gtgttaccat agttccgact tcgactattt gagtaacggc
    20041 ttcctgtgct acgacactat ttacaagtgt tttcacttcc ttaccatcgg cagaagtgct
    20101 cacagagtag aagttgctac gatgtccatt gacgccctta gtaatgactt gtgtttttcc
    20161 tttgagtaag agtggatttt cacgagtcac tgtggtaaat ggaatttctt ctttttggat
    20221 atccagtcta ggttttacct cagtagttgg tgcaagacca ctttcatcac ccttgtgagt
    20281 tacaggagcg ccaacttcaa ccacttggtt tataacttct ttggttacct ggctatcaag
    20341 gactgtttct gttgtttttc cattttcagt gagtacagag atgtaatgag ttcgctcacc
    20401 tttgactcct gctgtgataa tattttcctg accagctggg aggttaggat tttctttctt
    20461 gataacttca aatggaattt cttcagttct tgtgatgagt tctggtctgg tttcaacatt
    20521 ggcagccact tcattttcat ccaggcttcc tgaatgagtt gcagctggtt tgaggccttg
    20581 aagagcggct tttaggttgg ctacaagtgt gtcaagctca gcttgtttat tacggttgag
    20641 gttgtaattt agagctgttt tagctgcgtc aagggcctca agactttctt tactatatcc
    20701 ttctaagttt gtaggaattt tagctaattc ttcgcggaga gcattataat tagcacggaa
    20761 gtagtctttg ttgtggtctg caaaggcagt catgagttca aagatttcct cttccttgta
    20821 ttcagcgctt ggtctatctg cccagattga aagcatactt ccgactgttg gaagatctac
    20881 ttcaggatat ttggtagaag ctagttgatt gaatggtgtt tttccagtat tctcaatagc
    20941 tttcttgagg aaaccaccac catcttctgg tttttgacca agaatgtagt accagtcacc
    21001 gttggtattc aagaatttat agcctttgct tgctaggtat tgaggtgatg cgaggttata
    21061 tccccaccag cctttagacc agtaagaaat caagacatct ttgtcaaact gaacatcgtc
    21121 cttgtcttca tagtagaagc catcgttgaa ggccattggt tgaagccctc tttctttggc
    21181 catagctgcg agggtgttgg catattcggc aaatttgcca tagagttgat accacttgag
    21241 gtagtaccag ccttgggcac tagtcgcatc gttggcgtat tcgtcagtac caaagttgaa
    21301 aatctttgtt ttacctgcaa agaagtccat gtatttaccg atgagggctt ttacaaagtt
    21361 catcgcttct tcgtttttca agtccatagt tgtttttgaa actttatcaa agtgggcttg
    21421 aggattttta atacctaatt tttccatggc aaccagcata gcatccatgt gacctggact
    21481 gttaatagct gggatgagac cgatgtcctt agatttagcg tattcaatta gctctgttac
    21541 ttctgcctgt gttagtgcag taccgtttgg atcgtcgtag taagctttag ttccttcgat
    21601 aatagctttt ttaacgtcat cactagcata ggtttttccg ttggcagtaa tggtcatatc
    21661 atcgagtaga aagcgaagtc cgtcatttcc tagaaggaga tggacatcag aatatccgag
    21721 ctcactggcc ttgtctacga tgcgtttgag ctggttcaga gtaaagtatt tgcgtccagc
    21781 atcgattgag attaccttgt ttttggcaag tttttcaacc tcacgtttag cttcttcttc
    21841 tttttgagct tcaggcgtga gggtcaagtt gttgacagtt tcttgaagtt tagcaatggc
    21901 ttgatcaatc gtatcttgtt gggcacggct aaggttgcta tcgagagagc gaatagcttt
    21961 ttcagcttct tttacggccg cgacgctttc tgcagtataa cggttcaggt cttttggtac
    22021 ctcgttaagt gtttgctctg cagattcata atcagctgcg aagtattcag cgttggcatt
    22081 tgcaaaatga cgcatgagtt tgaagaggcg tgatggtgaa taacgtgcag atggagtgtc
    22141 agcccaagca gctaccatac taccgatgat tgggatatca gctccttctg tttttggtac
    22201 agaagtgatt ggtgtgtttt taataccatt gagcccctga tcgagattgt accagccttg
    22261 gccatcagcg tttcgtccaa gaacgtagta ccaagcatca ttggtattaa ggatttggtg
    22321 acctttttca gctagtagtt tagaagaagc gacatcgtag cctccccaac caccagtcca
    22381 catagaaacg atgatgtctt tgtcaaaact accaaagctt gtgtcgctat tgtagtagat
    22441 accgtcgtta aaggccattg gtttgagacc gtgcgatttt acaatacgag cgaggtcatt
    22501 ggcgtaggca ataaattttt catagccttt tacagggtag ccttcgtttg gatagtattt
    22561 atcagcttga agcacactcc aacctttagc atctgtcgca tcattggcat attcatcaag
    22621 tccgatgttg aagatttcag tctttttcgc gaaataagca gcatacttgt cgataagggc
    22681 ttttgtaaaa gcgacagctt gttcgttgtc aagattgaca gtacgggctg attccttccc
    22741 aaaatagcta aagttagggt tttggattcc caattctttc atggcattga gaatcgcatc
    22801 catgtgacca ggactattta ctgtcggaat gagaccgata cctttatctt tggcatagtt
    22861 aatcagatct gtcatttgac tttctgttaa gtgattgccg tttggatcgt tgtaataatc
    22921 atttgtacct ttttcaatgg cgcgtttgac atcgtcactg gcataggtct tgccgttagc
    22981 tgtgatgctc atatcgtcca acatgaaacg gagtccatca tttccgacta ataggtgtaa
    23041 atcagtgtag ccataatgtt tcgctttatc gatgatttcc ttgagctgtt ctggtgagaa
    23101 atatttacgt ccagcatcaa tagaaacaat tttctttttc gctagttttt catttacagt
    23161 tgcagcacgt tcctttcctg cctctgtttc cggtttgtca tcctctgctt tcgcttcatc
    23221 ttttttagct ggtttatcct tgtcagtctt gtctgtattt gactctttag aatcaacctc
    23281 tttcgcttct tcctttttag ggctagcttc ttctgccttt ttattagcag tttctttttc
    23341 agcagaagtt ggagttacca cttctgcttt atcactagga gttgaactaa cttcctcttg
    23401 tggtttttct tctgtttttg gaagactagc taccttatca gtagctggag tttctgtttc
    23461 tacagttttt ggagcttctg gttgaagctc tgctttaggt gtttcctcag tccgattttc
    23521 ggatgattga ggggaatcag aaaccgtatg gatggtcggt tggttttctg tagtagtagg
    23581 agtaactcca tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc
    23641 tgctcctaca gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa
    23701 acctcctgat tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt
    23761 tcttatatta acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata
    23821 taaaatttaa acttaagatt tcagattggt cggaaaaaat acgtatatat atctagtata
    23881 atttttggtt ctatttctat aaaatattcc acaaattata gaattttcca aaaataggta
    23941 agcgctacct ttttggtgtg gtataataag catagaaaaa gcccaagcga ttagctcagg
    24001 ctttcttctt agtgatcacg gtcacatgag ataaatttaa tcttgtagta atcagatcgt
    24061 ttgtaagttt cactgtattc taaaacttgg ccagttgatt cgagtttggt gattttagtt
    24121 tgtaggacag tagggaattg ttcatcgact ccgaggactg aagccgcatg ttctggagtt
    24181 ggaaagacta tttcgttgat ttcttcaaag tgttcatcat tcatgtgaat gtggtagtct
    24241 aacttgaaac gattatagat agaactatag tattcaaggt ttggataatt tgcgttgata
    24301 tattgttctg ggatgtagga tgtatggtag atataaacga caccgtttga ttcgcggata
    24361 cgttcaatct tgtagtagaa ttgatcgccg cgtagaccca atttttccaa gtaaacaagc
    24421 ttgtttccgc gttcaattga aagaacagtt accttatcat ctttagcatt gaagagttca
    24481 atatctgaaa actctacaag cttgtgtttg cgtgcacgtg aaacgaaggt tccttttcct
    24541 tgttggcgga caatatagcc atctttggca aggtcgttta aggcgcgaac aactgtgata
    24601 gagctgacat cgtacattga aatgagttct gcttcagtgt aaaatttatc tccactgcta
    24661 aactgcccag agatgatttt attttttaat tcgtctttta tgtattgata tttgggaatt
    24721 gccatatttt tacctctatt ttccttctcc ataggaaatt ttaccataaa agcgaaaaaa
    24781 atagtagtct tttgaataaa aaattagaat aatagtttga aaaattaagc gatataggga
    24841 ttgctcatat tttatcaatg tattctatac aaaattattt taggtcccat attccgaatt
    24901 taaagagcgt ttgaaatggg tctaaaaatg tttgaaacta attgaatgtg tgtataatag
    24961 taaaaatgca gtaaatatcc cgacaatttc tattgacaat tcaaacagat tggtttataa
    25021 ttaatataac aacaaatgaa agcgcaaact ttcgcggtcg gaaggtagtt ttatgacacg
    25081 atttgagata cgagatgatt tctatctcga tggaaaatca tttaagattt tatctggtgc
    25141 cattcattat tttagggttc ctccagagga ttggtatcat tcgctctata acttgaaggc
    25201 tcttggtttt aatacggtag agacttatgt tgcttggaat ttacacgagc ctcgtgaagg
    25261 tgagtttcat tttgaaggtg atctggattt agagaaattt ctccaaatag cgcaggattt
    25321 gggtctctac gcaattgtgc gtccgtctcc atttatctgt gcggaatggg aattcggtgg
    25381 cttaccagct tggctcttga ccaagaacat gcgaattcgc tcatccgacc cagtatatat
    25441 cgaggcagtt ggtcgctact atgatcagtt attgccaaga ctggtgcctc gtttgttgga
    25501 caatggtggc aatattctca tgatgcaggt tgaaaatgag tatggttctt acggagaaga
    25561 taaggcttac ctgagagcga ttcgacagct aatggaagag tgtggcgtaa cctgtcccct
    25621 ctttacatca gatggtccat ggcgagctac tctgaaagct ggaaccttaa ttgaagagga
    25681 cctctttgta acaggaaact ttggttctaa ggcaccttac aacttttcgc agatgcagga
    25741 attctttgat gaacatggta agaaatggcc actcatgtgt atggagttct gggatggttg
    25801 gttcaatcgc tggaaagaac cgattatcac acgggatcct aaggaattgg cagatgcagt
    25861 tcgagaggtt ttggaacaag gctctatcaa tctttacatg ttccacggtg gtacaaactt
    25921 tggtttcatg aatggttgct cagctcgagg aactttggac ctgccacaag ttacgtctta
    25981 tgattacgat gcccttctgg atgaagaagg aaatccaact gctaaatatc ttgcagtcaa
    26041 gaagatgatg gcaacacatt tttcagagta tccgcagttg gaaccactct acaaagagag
    26101 tatggagttg gatgctattc cactagttga aaaagtttct ttgtttgaaa ccttagatag
    26161 cttgtcaagt cctgtagaaa gtctctatcc tcaaaagatg gaggagctgg gacaaagtta
    26221 tggctaccta ctttatcgaa cagaaacaaa ctgggatgca gaagaagaaa gacttcgtat
    26281 cattgatggt cgagataggg cccagctgta tgtcgatggt cagtgggtta aaactcaata
    26341 tcagacagag attggggaag atatttttta tcaaggtaaa aagaaagggc tatctaggtt
    26401 agatatcttg atagaaaata tggggcgtgt caactatggg cataagttct tagcggatac
    26461 gcaacgtaag ggaattcgga caggggtctg taaggatctg catttcttac taaactggaa
    26521 acactatcca ctcccactag acaatcctga gaaaattgat ttttcaaaag gatggactca
    26581 aggacaacca gccttttacg cttatgactt tacagtcgaa gagccaaaag atacttacct
    26641 agacttgtct gagtttggta agggggttgc ctttgtcaat gggcagaatc taggacgttt
    26701 ttggaacgtt ggcccaactc tctcacttta tatccctcat agctatctca aggaaggtgc
    26761 caaccgcatc attatctttg aaacagaagg tcaatataaa gaagagattc atttaactcg
    26821 taaacctaca ctaaaacata taaaggggga aaacttatga caattgtagg atgccgtatt
    26881 gatggacgtt tgatccacgg acaagtagcc aatctttggg ctggaaaact aaatgtttca
    26941 cgcattatgg ttgtagacga cgaagttgtc aacaacgata ttgaaaagag tggtttgaaa
    27001 cttgcgacac caccaggtgt gaaattgagt attttgccag ttgagaaagc tgcagccaat
    27061 attcttgctg gtaaatacga tagccaacgt ctctttatcg tggctcgtaa accagaccgc
    27121 ttccttggtt tggtagaagc aggtgtacca cttgaaaccc ttaatgttgg gaatatgtct
    27181 caaacaccag aaacacgttc tattacacgt tctatcaacg tagtagacaa ggatgtggaa
    27241 gacttccaca aactggcaga aaaaggtgtt aaacttactg ctcagatggt tccaaatgat
    27301 ccaatttcag actttttgag cttattaaaa taggaaaaaa atttttagga ggtcattgtt
    27361 atgatacaat ggtggcaaat tttacttctc actttgtact cagcttatca aatctgtgat
    27421 gagttgacga tcgtttcatc tgcaggttct cctgtatttg ctggtttcat tactggttta
    27481 atcatgggag atgtgactac tggtttactt atcggtggta acttgcaact gttcgttctt
    27541 ggggttggta ccttcggtgg tgcttctcgt atcgacgcaa cttctggtgc ggttcttgcg
    27601 acagccttct ctgtttcaca aggaattgat gcaccgcttg ccattactac aatcgctgta
    27661 ccagtagcag ctctcttgac ttacttcgac gttcttggtc gtatgactac taccttcttc
    27721 gctcaccgtg tggatgctgc aatcgaacgc tttgactata aaggtattga acgcaactac
    27781 ttgcttggtg cgattccgtg ggctctatct cgtgcccttc cagtcttctt tgcccttgct
    27841 tttggtggtg cctttgtaca atcagtagta gacttcgttg aagcctacaa atgggttgca
    27901 gatggcttga cactcgcagg acgtatgctt ccaggtcttg gatttgcaat cttgcttcgt
    27961 taccttccag ttaaacgtaa ccttcactac cttgctatgg gatttggttt gacagctatg
    28021 ttgactgttc tttactcata tgtaacaggt cttggtggcg ctgttgctgg tatcgtaggt
    28081 actcttcctg ctgaagttgc tgaaaaaatt ggtttcgtga acaacttcaa aggtttgtct
    28141 atgattggta tttctatcgt aggtattttc cttgcagtgc ttcacttcaa aaatagccaa
    28201 aaagtagctg tagcagcacc ttctacacca tcagaaagtg gggaaatcga agatgacgaa
    28261 ttctaattac aaacttacaa aagaagattt taatcaaatc aacaaacgta gcttgtttac
    28321 tttccaatta ggttggaact acgaacgtat gcaagcttct ggttaccttt acatgatctt
    28381 gcctcagttg cgtaaaatgt atggtgatgg aactcctgaa ttgaaagaaa tgatgaaagt
    28441 tcatactcaa ttcttcaata cttcaccatt cttccatacc attatcgctg gttttgacct
    28501 tgccatggaa gaaaaagatg gtgtaggttc aaaagacgct gttaacggta tcaagacagg
    28561 tttgatggga ccattcgctc ctcttgggga tacaatcttt ggttcacttg tacctgctat
    28621 catggggtca gtcgcagcaa ctatggctat cgctggccaa ccttggggga tcttcctttg
    28681 gattgcagtt gcagtagcgt atgacatctt ccgttggaaa cagttggaat ttgcttacaa
    28741 agaaggggtt aaccttatca acaacatgca aagtaccttg acagctttga ttgacgctgc
    28801 atctgtactt ggtgtcttca tgatgggtgc tcttgtagca acagtgatta actttgaaat
    28861 ttcttacaag ttgccaatcg gtgaaaagat gattgatttc caagacatct tgaaccaaat
    28921 cttcccacgt ttgcttccag caatctttac tgcctttatc ttctggttgc ttggtaaaaa
    28981 aggtatgaac tctactaaag ctatcggtat tattatcgta cttgctttgg ctctttctgc
    29041 ccttggtcac tttgcacttg gaatgtaatt ccttatgact aaatcattaa ttttggtgag
    29101 ccatggtcgc ttctgtgagg agcttagagg tagcacagaa atgattatgg gcccacaaga
    29161 caacatttac acagtagctc ttcttccaga agatggccca gaagaattta ctgctaaatt
    29221 tgaagctgtt attgaaggat tggatgattt cctagtcttt gcggatcttc tcggtgggac
    29281 accttgtaat gtggtgagtc gcttgatcat ggaaggtcgt gatattgacc tttacgcagg
    29341 gatgaatctt ccaatggtga ttgaatttat caatgcgagc cttacaggcg cagatgcgga
    29401 ctacaagagc cgtgctgcag aaagcattgt gaaagttaat gacctgttag cgggcttcga
    29461 tgatgacgaa gatgaataat actcttcgaa aatctcttca aactacgtca acgtcgcctt
    29521 gccgtaggta tatgttactg acttcgtcag tcttatccgg caacctcaaa acggtgtttt
    29581 gagctgactt cgtcagtctt atccggcaac ctcaaagcag tgctttgagc agcctgcggc
    29641 tagtttccta cagattttag ttggaactcg attcaattca tgtgacaacg tgaaaatcgt
    29701 tagagcattt tatatagaat atacatggga atggagctta ctcccattcc catatttaat
    29761 agaaaaagag gaactcaatg ctacattata caaaagaaga cttgctcgaa ttgggtgcag
    29821 aaatcactac gcgtgaaatc taccaacagc ctgatgtatg gagagaagct tttgaatttt
    29881 atcaagcaaa acgtgaagaa attgcagcct ttctacaaga aatcgctgat aaacatgact
    29941 atattaaggt tatcttgaca ggtgctggga cttctgctta tgtgggagat accttgctac
    30001 cttactttaa ggaagtctat gacgaacgca aatggaattt caatgctatt gcgacaacag
    30061 atatcgttgc caaaccagca acctatttga aaaaagatgt ggcaactgtc cttgtgtctt
    30121 ttgctcgtag tgggaactcg cctgaaagtg tggcgactgt tgatttggcc aaatccttgg
    30181 tggatgagct ttatcaagtg acgattactt gtgcagcaga tggtaaattg gctcttcaag
    30241 ctcacggtga tgaccgtaat ctcttgctct tgcaaccagc tgtctctaat gatgctggat
    30301 ttgccatgac ttctagcttt acgtctatga tgttgacaac tctcttggtc tttgatccta
    30361 cagaatttgc tgttaagtct gaacgttttg aagttgtatc tagtcttgcc cgtaaagttt
    30421 tagacaaggc agaagatgtc aaagagctcg ttgatttaga ctttaaccgt gtcatctatc
    30481 taggcgctgg tcctttcttt ggacttgctc atgaagctca gctcaagatt ttggaattaa
    30541 ctgctggtca agttgcgacc atgtatgaaa gcccagttgg cttccgtcac ggtccaaaat
    30601 ctcttatcaa cgacaataca gttgttttgg tctttggtac aacgacggac tacactcgta
    30661 agtacgactt ggacttggtt cgtgaagttg ctggtgacca gattgctcgt cgtgttgtgc
    30721 ttttgagtga tcaagctttt ggtcttgaaa atgtcaaaga agtggtcctt ggttgtggcg
    30781 gtgtcttgaa tgatatttac cgtgtcttcc cttacatcgt ttatgcccaa ctctttgccc
    30841 tattgacttc actcaaggta gaaaataaac cagatacacc gtctcctaca ggtacagtaa
    30901 accgtgtagt acaaggtgtc ataattcacg aatatcaaaa gtaagacagt gtttatgaat
    30961 tcttgacaag aggatttgta aattatcaga taaaccatag attgtcagta cgctttctat
    31021 ggtttgtttg cttgagagaa atagtaaaag gagaacagaa tgaaagcata cacagagcgt
    31081 gtatttggaa atgttgaggg tgaggatgtc ttggcctatc gatttgagac agacggtggc
    31141 taccaacttg aggttatgac ttatggtgcg actatcttgc gctatgtcgc acctgacaag
    31201 gctggaaatt ttgccaatgt tatcttggga tttgatgact ttgatagtta tgtaggcaat
    31261 agtcccaagc atggagcaag tgtaggtcct gtagcgggtc gtattgcagg tgcgaccttt
    31321 gagctcaatg gtaagaccta tgaccttgag gttaataatg ctagcaactg taatcacagt
    31381 ggttcaactg gttgggattc cagcttgttt gaagttgaag aagtaagcga tcatggcttg
    31441 actctctaca cagagcgtac agatgggaca ggagggttcc ctggaaatct caagatttgg
    31501 atcagttatc acttggaaga aactggtgcc tatgaaatca gctacaaggt aacgaccgat
    31561 caggatacgc tggtcaatcc aaccaaccac agctatttca acttgtctgg tgatttcacg
    31621 cagacgattg accgtcatgt cttccaacta aacacagagg gcatttactc aatcgctcct
    31681 gacggtgttc ctgccaaaac tccagaagcc aaccgtgatg tggtcaaaca catctacaat
    31741 ggtgccttgt tgaaggatat ctttgcagaa gaagatgagc aaatccagct ggcatcaggt
    31801 ttggatcatc catttgccct tcctgcaggc catgacaatg ctggattcct ttatgaccaa
    31861 aattcaggtc gcttcctgct tttcaagaca gaagctcctt gctttgtggt ctacacagca
    31921 aactttgtgg atgaaagtgt catcatagga ggtcagccaa tgctacagca caatgggatt
    31981 gctcttgaag cgcaagcttt accagatgcc attcacagtg accttaaagg ccaagtcatt
    32041 cttaaagctg gtcaaacctt caccagtaag acacgttatg aacttgttgt gaaataaaaa
    32101 aagctggtca aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt
    32161 gataatatgc gttttattat gaaatgattt actttatatt atcctgaaat ggtgttattt
    32221 ttgagttatc tggcttgact ttcttgatgg aaattatata atagttgtaa caatgataat
    32281 tacaactaga aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca
    32341 gagacagctt taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt
    32401 ggtttagaaa tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc
    32461 ttggtacagc tgattcaagc acaagagagc ggagaagtga gggaatatta tggtctttac
    32521 catttggcca ttctcttgcc cacacgcaag gctttagctg atgtcttgaa acacctgaca
    32581 gatttacaaa ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg
    32641 gaagatttgg agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat
    32701 attcgagaag atggacgcat tatcggagtg acagaggctc ttgcggcgca ggacatttat
    32761 gagttggggg aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt
    32821 catctttccg tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta
    32881 gaggataaat tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat
    32941 ttagcagtta acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt
    33001 ttagcctact atgtcatcga agtcgcacac aaaaaagaac tattaacgat tgcccaacga
    33061 gcacaagaag ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac
    33121 tcagatggca tcgtgacccg tattcgttta gcaaggtaaa attaggaatt tttaataagt
    33181 tataagtatt gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga
    33241 tgggcgagaa ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg
    33301 aaaaagaaat gacaaattca aagtatatta cttgtttgaa acgttcagag ggccagttgt
    33361 gtgggattca aaagatgatt gaaggagatc gtgactgtgc tgatattgtg acgcaactga
    33421 cagcagtgag atctagtgta gagcgcgtga ttgagatgat aattaccgaa aatcttactg
    33481 aatgtatcaa tcagccacta gatgattctg aagctcaaaa ggaacgctta gaaaaggcta
    33541 tccgatactt gattaaacgg aaataaatga atgttttgag acgatatgtg caaaggtcta
    33601 ttaactatta gaatagttta atgggagtca aaagaagttg taaaaaatct ttaaaattaa
    33661 aaaaacgcat agtatcaggt attgaaatgt actgacccca aaaagttaga ttttttctgt
    33721 ctaacttttg gggtgcagtt cataagaacc ttggtaatat gcgttttatt atggggagat
    33781 ttatactttt cgaaaatctc ttcaaaccag gtcagcttca ccttgccgta gatatggtta
    33841 ctgacttcgt cagttctatc cacaacctca aaacagtgtt ttgagctgac ttcgtcagtt
    33901 ccatccacaa ccttaaaaca gtgttttgag ctgacttcgt cagttccatc cacaacctta
    33961 aaacagtgtt ttgagcagcc tgcggctaac ttcctagttt gcactttaat tttcattgag
    34021 tattacttca tcttctcatg aaattgagtt tttgcccagt tcctcttgat tattctactt
    34081 gaccaggcca agcattcata ccaccttcta cgttggtaac ggtgaggcct tgggagatga
    34141 gaaattggca ggtagatgca gagcggactc ctccttgaca aataacatag tattcatggt
    34201 caggtttgag ttctttgtag ccttgctcta aggtacttaa tggaagattt ttggcacctg
    34261 gtgcatgtcc tgcttggaat tcatgtgctt cacggacatc gataagttct agattttcat
    34321 tttggtattt tccataaaag tcagccatgc tgatactagt ttccatattc tactccttct
    34381 gggttaacca ttttgtatag tgaataagcg ccgtcaaggt tttgggcggt aaatcctgct
    34441 tgcttgagga taggctctgc gatatagctg cgcaaaccac tgtggcagct gacgatgtag
    34501 gcttgttttt tgtccagttc atcagcttcc tccttgacac tttgtcagtt tttgatacaa
    34561 tagtacaaaa ttagaggagg tgggctatga ttcagaaaca tgcgattcct attttagagt
    34621 ttgatgacaa tcctcaggcg gttatcatgc ccaatcacga ggggctggac ttgcagttgc
    34681 caaagaagtg tgtttatgca tttttagatg aggagattga ccgctatgca agggaagtag
    34741 gggcggattg tgtcggcgaa ttcgtttctg ctaccaagac ctatccagtc tatgtcatca
    34801 actacaaggg tgaggaggtc tgtctggctc aggctcctgt tggctccgct ccagcagccc
    34861 agtttatgga ttggttgatt ggctatggtg tggagcagat tatctctact gggacctgtg
    34921 gtgttctagc tgatatagag gaaaatgcct ttctagtccc tgttcgcgct ctgcgagatg
    34981 aaggagccag ttaccactat gtggcacctt ctcgttatat ggaaatgcag ccagaggcta
    35041 ttgctgctat tgaggaagtt ttggaagaca gagggattcc ttatgaagaa gtcatgacct
    35101 ggacgacaga cggtttttac cgagaaacgg ctgaaaaggt ggcttatcgt aaggaagaag
    35161 gctgtgctgt tgtggagatg gagtgttctg ctcttgcggc agtagctcaa ttgcgtgggg
    35221 ttctctgggg tgaattgttg ttcacagcag attctctagc ggacttggac cagtacgaca
    35281 gtcgtgactg gggctcggaa gcttttaata aggcgctaga actgagttta gcaagtgttc
    35341 accaccttta gttgtactgg caaaggattt gttttatcat aaaatgtcta gctcatactt
    35401 ttcaaaaata tgtttaaacg aggtcacctt cctcttgtcc taagcatgtt gaggttggga
    35461 aaaatcttta aaatcagaaa aacgtatcat atcaggtgat gaaaaccttg atactatgcg
    35521 ttttatgttg gtaagattta gagtgagatg aaatgatact cttcgaaaat cttttcaaac
    35581 caggtcagct tcaccttgcc gtaggtatat gttactgact tcgtcagtct tatccggcaa
    35641 cctcaaaacg gtgttttgag ctgacttcgt cagttctatt tgcaacctca aaacagtgtt
    35701 ttgagcaatc tgtgactagc tttctaatcg atgccttggt tctcattgcc tataatcaaa
    35761 aagagaaatt ttctcctgaa aagcatatag agtagctggc gttaaaagct cctgtcttgc
    35821 ttttttgacc tatagtcaca tctatcaagt attgttcttg cctaagctat caataaaaag
    35881 gtggcatttt ttaggcttgg tgttagtaga ttttgcctta tcctatctaa gtcatttcga
    35941 actttttatg gtacaatgga aacatgttat tcaaattatc taaggaaaaa atagagctag
    36001 gcttatctcg tttatcgcca gcccgtcgta tttttttgag ttttgccttg gtcattttac
    36061 taggctctct tcttttgagc ttgccctttg tccaagttga aagctcacga gcgacttatt
    36121 ttgatcatct tttcactgct gtctctgcag tctgtgtgac aggtctctca acccttccag
    36181 tagctcacac ctataatata tggggccaaa taatctgttt gctcttgatt cagatcggtg
    36241 gtctagggct catgaccttt attggggttt tctatatcca gagcaagcaa aagcttagtc
    36301 ttcgtagccg tgcaactatt caggatagtt ttagttatgg agaaactcga tctttgagaa
    36361 agtttgtcta ttctattttt ctcacgacct ttttggttga gagcttggga gctattttgc
    36421 ttagttttcg ccttattcct caacttggct ggggacgtgg tctttttagt tccatttttc
    36481 tagcgatctc agccttctgt aatgccggtt ttgataattt agggagcacc agtttatttg
    36541 cttttcagac cgatttactg gtcaatctgg tgattgcagg cttgattatt acaggcggcc
    36601 ttggttttat ggtctggttt gatttggctg gtcatgtagg aagaaagaaa aaaggacgtc
    36661 tgcactttca tacgaagctt gtactattgt tgactatagg tttgttgtta tttggaacgg
    36721 caactactct ctttcttgag tggaacaatg ctggaacgat tggcaatctc cctgttgccg
    36781 ataaggtttt agttagcttt tttcaaacag tgacgatgcg aacagctggc ttttctacga
    36841 tagattatac tcaggctcat cctgtgactc ttttgattta tatcttacag atgtttctag
    36901 gtggggcacc tggaggaaca gctgggggac tcaagattac gacatttttt gtcctcttgg
    36961 tctttgcacg aagtgagctt ctaggcttgc ctcatgccaa tgttgcgaga cgaacgattg
    37021 cgccgcgaac ggttcaaaaa tcctttagtg tctttattat ctttttgatg agcttcttga
    37081 taggattgat tctgctaggg ataacagcca aaggcaatcc tccctttatc cacctcatat
    37141 ttgaaaccat ttcagctctt agtacagttg gtgtaacggc aaatctgact cctgaccttg
    37201 ggaaattggc tctcagtgtt atcatgccac ttatgtttat gggacgaatt ggtcccttga
    37261 ccttgtttgt tagcttggca gattaccatc cagaaaagaa agatatgatt cactatatga
    37321 aagcagatat tagtattggt taagaaagga aagagcatgt cagatcgtac gattggaatt
    37381 ttgggcttgg gaatttttgg gagcagtgtc ctagctgccc tagccaagca ggatatgaat
    37441 attatcgcta ttgatgacca cgcagagcgc atcaatcagt ttgagccagt tttggcgcgt
    37501 ggagtgattg gtgacatcac agatgaagaa ttattgagat cagcagggat tgatacctgc
    37561 gataccgttg tagtcgcgac aggtgaaaat ctggagtcga gtgtgcttgc ggttatgcac
    37621 tgtaagagtt tgggggtacc gactgttatt gctaaggtca aaagtcagac cgctaagaaa
    37681 gtgctagaaa agattggagc tgactcggtt atctcgccag agtatgaaat ggggcagtct
    37741 ctagcacaga ccattctttt ccataatagt gttgatgtct ttcagttgga taaaaatgtg
    37801 tctatcgtgg agatgaaaat tcctcagtct tgggcaggtc aaagtctgag taaattagac
    37861 ctccgtggca aatacaatct gaatattttg ggtttccgag agcaggaaaa ttccccattg
    37921 gatgttgaat ttggaccaga tgacctcttg aaagcagata cctatatttt ggcagtcatc
    37981 aacaaccagt atttggatac cctagtagca ttgaattcgt aaagagggat gacccctctt
    38041 ttttgatgcc caagatggca aatagagaca gaagcccctt gtcttctagt aaaagttctt
    38101 caaaggctgg actttatggt aaaatagaag gaagtgacaa gagagagtaa tactcaatga
    38161 aaatcaaaga tcaaactagg aaactagctg cgggctgctc aaaacactgt tttgaggttg
    38221 tggatagaac tgacgaagtc agctcaaaac actgttttga ggttgcagat agaactgacg
    38281 aagtcagtaa catctatacg gcaaggcgac gttgacgcgg tttgaagaga ttttcgaaga
    38341 gtataagaaa aaatcagtcc cctaaaggag cagattatga agttattgtc tatcgccatt
    38401 tctagctata atgcagcagc ctatcttcat tactgtgtgg agtcgctagt gattggtggt
    38461 gagcaagttg ggattttgat tatcaatgac gggtctcagg atcagactca ggaaatcgct
    38521 gagtgtttag ctagcaagta tcctaatatc gttagagcca tctatcagga aaataaatgc
    38581 catggcggtg cggtcaatcg tggcttggca gaggcttctg ggcgctattt taaagtagtt
    38641 gacagtgatg actgggtgga tcctcgtgcc tacttgaaaa ttcttgaaac cttgcaggaa
    38701 cttgagagca agggtcaaga ggtggatgcc tttgtgacca attttgtcta tgaaaaggaa
    38761 ggtcagtctc gtaagaagag tatgagttac gagtcagtct tgcctgttcg gcagattttt
    38821 gactaggacc aggtcggaaa tttctccaaa ggccagtata tcatgataca ctcgctgatt
    38881 tatcggacag atttgttgcg tgctagccag ttctaactgc ctgaacatac tttttatgtc
    38941 gatgatctct ttgtctttac gccccttcag caggtcaaga ccatgtacta tctgcctgtc
    39001 gatttctatc gttatttgat tgggcgtgag gaccagtctg tcaatgagca agtgatgatt
    39061 aagcgcattg accagcaact caaggtcaat cgactcttgg tagaccagct tgatttgtcc
    39121 caagtgagtc atcctaaaat gcgagaatat ctgctgaatc atattgaaat cacgacggtg
    39181 atttccagta ccctgctcaa ccgatctgaa acagcggagc atctggcaaa aaaacgccaa
    39241 ttgtggacct atattcagca gaaaaatcca gaagtctttc aggctattcg taagaccatg
    39301 ttgagccgtt tgaccaaaca ttctgtcttg ccagatcgca aactgtccaa tgtcgtctat
    39361 caaatcacca aatctgttta tggatttaat taatataagt gttttataag agggatttaa
    39421 gaaaaatttt aactttttct tagtcctttt taatttcagg agattatact agagtcatca
    39481 aataaagaaa gactctaagg agaatcctat gaaattcaat ccaaatcaaa gatatactcg
    39541 ttggtctatt cgccgtctca gtgtcggtgt tgcctcagtt gttgtggcta gtggcttctt
    39601 tgtcctagtt ggtcagccaa gttctgtacg tgccgatgtg gtcaatccga ccccaggtca
    39661 agtcttacct gaagagacat cgggaacgaa agagggtgac ttatcagaaa aaccaggaga
    39721 caccgttctc actcaagcga aacctgaggg cgttactgga aatacgaatt cacttccgac
    39781 acctacagaa agaactgaag tgagcgagga aacaaactct tctagtctgg atacactttt
    39841 tgaaaaagat gaagaagctc aaaaaaatcc agagctaaca gatgtcttaa aagaaactgt
    39901 agatacagct gatgtggatg ggacacaagc aagtccagca gaaactactc ctgaacaagt
    39961 aaaaggtgga gtgaaagaaa atacaaaaga cagcatcgat gttcctgctg cttatcttga
    40021 aaaagctgaa gggaaaggtc ctttcactgc cggtgtaaac caagtaattc cttatgaact
    40081 attcgctggt gatggtatgt taactcgtct attactaaaa gcttcggata atgctccttg
    40141 gtctgacaat ggtactgcta aaaatcctgc tttacctcct cttgaaggat taacaaaagg
    40201 gaaatacttc tatgaagtag acttaaatgg caatactgtt ggtaaacaag gtcaagcttt
    40261 aattgatcaa cttcgcgcta atggtactca aacttataaa gctactgtta aagtttacgg
    40321 aaataaagac ggtaaagctg acttgactaa tctagttgct actaaaaatg tagacatcaa
    40381 catcaatgga ttagttgcta aagaaactgt cgaaaaagct gtta
//
LOCUS       DAVAZV010000013        39608 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVAZV010000013 DAVAZV010000000
VERSION     DAVAZV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.013"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            470..1591
                     /gene="mnmA"
                     /locus_tag="VQT46_000663"
     CDS             470..1591
                     /gene="mnmA"
                     /locus_tag="VQT46_000663"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET2370732.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRRLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1732..2187
                     /locus_tag="VQT46_000664"
     CDS             1732..2187
                     /locus_tag="VQT46_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2370733.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELDVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLQNIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2197..4110
                     /gene="mnmG"
                     /locus_tag="VQT46_000665"
     CDS             2197..4110
                     /gene="mnmG"
                     /locus_tag="VQT46_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET2370734.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            4299..4388
                     /locus_tag="VQT46_000666"
                     /pseudo
     CDS             4299..4388
                     /locus_tag="VQT46_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4534..6213)
                     /locus_tag="VQT46_000667"
     CDS             complement(4534..6213)
                     /locus_tag="VQT46_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2370735.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(6215..6448)
                     /locus_tag="VQT46_000668"
     CDS             complement(6215..6448)
                     /locus_tag="VQT46_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET2370736.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6830..7051
                     /locus_tag="VQT46_000669"
     CDS             6830..7051
                     /locus_tag="VQT46_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000184674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370737.1"
                     /translation="MTNQVLEENYLCDSLLAFSPPRDLCRLVCILLWIKCLDALLMLG
                     FFVWGCRDSRFTTRKFHPIYQDEVVFAFF"
     gene            complement(7264..7416)
                     /gene="cibB"
                     /locus_tag="VQT46_000670"
     CDS             complement(7264..7416)
                     /gene="cibB"
                     /locus_tag="VQT46_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET2370738.1"
                     /translation="MMKDLNNCREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(7418..7603)
                     /gene="cibA"
                     /locus_tag="VQT46_000671"
     CDS             complement(7418..7603)
                     /gene="cibA"
                     /locus_tag="VQT46_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET2370739.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            7781..8464
                     /gene="tsaB"
                     /locus_tag="VQT46_000672"
     CDS             7781..8464
                     /gene="tsaB"
                     /locus_tag="VQT46_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET2370740.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMESLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLTHTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMPEAHLSFEEVLEKVKGASQVTFVGEVGPF
                     VEQIQEHLPRTNYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            8461..8898
                     /gene="rimI"
                     /locus_tag="VQT46_000673"
     CDS             8461..8898
                     /gene="rimI"
                     /locus_tag="VQT46_000673"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET2370741.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            8888..9898
                     /gene="tsaD"
                     /locus_tag="VQT46_000674"
     CDS             8888..9898
                     /gene="tsaD"
                     /locus_tag="VQT46_000674"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET2370742.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(9944..11244)
                     /locus_tag="VQT46_000675"
                     /pseudo
     CDS             complement(9944..11244)
                     /locus_tag="VQT46_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11520..11871)
                     /locus_tag="VQT46_000676"
                     /pseudo
     CDS             complement(11520..11871)
                     /locus_tag="VQT46_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11978..12270)
                     /locus_tag="VQT46_000677"
                     /pseudo
     CDS             complement(11978..12270)
                     /locus_tag="VQT46_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            12513..13719
                     /locus_tag="VQT46_000678"
                     /pseudo
     CDS             12513..13719
                     /locus_tag="VQT46_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            13712..14360
                     /locus_tag="VQT46_000679"
                     /pseudo
     CDS             13712..14360
                     /locus_tag="VQT46_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397244.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            14370..15986
                     /locus_tag="VQT46_000680"
     CDS             14370..15986
                     /locus_tag="VQT46_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370743.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLSGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            16006..16850
                     /locus_tag="VQT46_000681"
                     /pseudo
     CDS             16006..16850
                     /locus_tag="VQT46_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            16918..18419
                     /locus_tag="VQT46_000682"
                     /pseudo
     CDS             16918..18419
                     /locus_tag="VQT46_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            18431..19180
                     /locus_tag="VQT46_000683"
     CDS             18431..19180
                     /locus_tag="VQT46_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET2370744.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            19193..20365
                     /locus_tag="VQT46_000684"
     CDS             19193..20365
                     /locus_tag="VQT46_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2370745.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTRQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD"
     gene            20760..21623
                     /locus_tag="VQT46_000685"
     CDS             20760..21623
                     /locus_tag="VQT46_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2370746.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            21909..22142
                     /locus_tag="VQT46_000686"
     CDS             21909..22142
                     /locus_tag="VQT46_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370747.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            22164..22841
                     /locus_tag="VQT46_000687"
     CDS             22164..22841
                     /locus_tag="VQT46_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2370748.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVKRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            22853..23518
                     /locus_tag="VQT46_000688"
     CDS             22853..23518
                     /locus_tag="VQT46_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2370749.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAILFGVSHISNHGWVLTDFFVYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            23590..24816
                     /locus_tag="VQT46_000689"
     CDS             23590..24816
                     /locus_tag="VQT46_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2370750.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLLNLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPISTLFLRNQPFLNLQTGQSLALLATLEL
                     SALILGSLMSGYLQHTISIKIALYASLLLQLLLLVGFATAHFGLILIFSFLDAFFAGI
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALGTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(25167..25244)
                     /locus_tag="VQT46_000690"
                     /pseudo
     CDS             complement(25167..25244)
                     /locus_tag="VQT46_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            25315..25971
                     /locus_tag="VQT46_000691"
     CDS             25315..25971
                     /locus_tag="VQT46_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET2370751.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQIMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            25961..26284
                     /locus_tag="VQT46_000692"
     CDS             25961..26284
                     /locus_tag="VQT46_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HET2370752.1"
                     /translation="MVSKYLLLAVIFSDLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAV
                     LRLVF"
     gene            26388..27218
                     /locus_tag="VQT46_000693"
     CDS             26388..27218
                     /locus_tag="VQT46_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370753.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NSSPKPFNYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYQMAV
                     NNISYTKERAEKYLYAAPTVKDPNVLVVKKDDSSIKSLDDVGGKSTEVVQGTTSAKQL
                     EDYNKQHSDNPTILNYTKANLQQIMGHLSDGQFDYKISDKITVETVIKNQGLDNLKVI
                     DLPSDQQPYVYPLLAKGQDELKTFVDKRIQELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            27259..27336
                     /locus_tag="VQT46_000694"
                     /pseudo
     CDS             27259..27336
                     /locus_tag="VQT46_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC protein"
     gene            27440..28270
                     /locus_tag="VQT46_000695"
     CDS             27440..28270
                     /locus_tag="VQT46_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370754.1"
                     /translation="MKKIVKYSSLAALALVAAGVLAACSGGAKKEGQAASKKEIIVAT
                     NGSPKPFIYEENGELTGYEIEVVRAIFKDSDKYNVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            28424..29278
                     /locus_tag="VQT46_000696"
     CDS             28424..29278
                     /locus_tag="VQT46_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2370755.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            29378..30751
                     /locus_tag="VQT46_000697"
     CDS             29378..30751
                     /locus_tag="VQT46_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET2370756.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            30744..31805
                     /locus_tag="VQT46_000698"
     CDS             30744..31805
                     /locus_tag="VQT46_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET2370757.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGGQ"
     gene            31807..32499
                     /locus_tag="VQT46_000699"
     CDS             31807..32499
                     /locus_tag="VQT46_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370758.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(32529..33098)
                     /locus_tag="VQT46_000700"
     CDS             complement(32529..33098)
                     /locus_tag="VQT46_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2370759.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            33233..33847
                     /locus_tag="VQT46_000701"
     CDS             33233..33847
                     /locus_tag="VQT46_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET2370760.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            33849..35495
                     /locus_tag="VQT46_000702"
     CDS             33849..35495
                     /locus_tag="VQT46_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2370761.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDR
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQKYFEHRASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            35507..36793
                     /locus_tag="VQT46_000703"
     CDS             35507..36793
                     /locus_tag="VQT46_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2370762.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVPITKQLFIQFVMDVF
                     HLFEHLKADDLTDIVKTIHAIQSFDELVPYIKETLSSFFGQYRMNENVVSVLEVIGCD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            36854..37387
                     /locus_tag="VQT46_000704"
     CDS             36854..37387
                     /locus_tag="VQT46_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370763.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRTAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKASAEEEETEELA"
     gene            37465..37935
                     /gene="nrdI"
                     /locus_tag="VQT46_000705"
     CDS             37465..37935
                     /gene="nrdI"
                     /locus_tag="VQT46_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET2370764.1"
                     /translation="MKIISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(38228..39490)
                     /locus_tag="VQT46_000706"
     CDS             complement(38228..39490)
                     /locus_tag="VQT46_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET2370765.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFSGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT        12026 a         6862 c         8542 g        12178 t
ORIGIN      
        1 ttaggtgccc ttgcagtcaa cacaactgta gatggctata aagtcaatgc caatggtgaa
       61 tgggtttaag ccgattaaat taaatcatgt taagaacatt tgacatttta attttgaaac
      121 aaagataagg ttcgattgaa tagatttatg ttcgtattct ttaggtacct atcttatgat
      181 ttcaggaaat gtcattaaaa aaacgactcc ttttctctaa cttgaaaaat agattagaga
      241 aaatgggttg ttttatttat tatagttatt tgaatgaaga taagaagaag gtatactcac
      301 atcattcaca taatctgtat gttgactata agtttaaaaa aacaattttt aagctcttcc
      361 ttgtcttctc caaccaagcg tgttataatg aatactgctc aagcgacctt caatcgtgaa
      421 gcacacacga ccttcaatcg tgaataaacg aatagatggg agacttacca tgagtgataa
      481 ctctaaaaca cgtgttgtcg tggggatgag tggtggtgtt gattcgtcgg tgacggctct
      541 tttgctcaag gagcagggct acgatgtgat cggtatcttc atgaagaact gggatgacac
      601 agatgaaaac ggcgtctgta cggcgaccga agattacaag gatgtggttg cggtggcaga
      661 ccagattggc attccctact actctgtcaa ttttgaaaaa gagtactggg accgcgtttt
      721 tgagtatttc ctagcggaat accgtgcagg gcgcacgcca aatccggacg ttatgtgcaa
      781 caaggaaatc aagttcaagg cctttttgga ctatgccatg accttggggg cagactatgt
      841 agcgactggg cattatgctc gagtggcgcg tgatgaggac ggcactgttc acatgcttcg
      901 tggcgtggac aatggcaagg accagaccta tttcctcagc caactttcgc aagaacaact
      961 ccaaaaaacc atgttccctc tgggacattt ggaaaagcct gaagtacgca gactagcaga
     1021 agaagcaggc ctttcgactg ctaagaagaa agactcgaca gggatttgct ttatcggaga
     1081 aaagaacttt aaaaactttc tcagcaacta cctgccagct cagcctggtc gcatgatgac
     1141 tgtggatggt cgcgatatgg gcgagcatgc aggtcttatg tactatacaa tcggtcagcg
     1201 tggcggactc ggtatcggtg ggcaacacgg cggtgacaat gccccttggt tcgttgtcgg
     1261 aaaagatcta agcaagaata ttctctatgt aggacaagga ttctaccatg attcgctcat
     1321 gtcaactagc ctagaagcca gtcaagtcca ctttactcgt gaaatgccag aagagtttac
     1381 gctagaatgt acggctaaat tccgttaccg tcagcctgac tctaaggtga ccgtccatgt
     1441 caaaggagac aaggcagaag ttatctttgc ggaaccacaa cgcgcgatta caccaggaca
     1501 ggcagttgtc ttttacgatg gcgaagagtg tctaggtggc ggtttgattg acaatgctta
     1561 ccgcgatgga caagtttgtc agtacattta gattgacaaa ttttctcaat ttgctacaat
     1621 aataacagca atagaaatga tggtcaaagc tcatggatgt tgcaggcttt tttgtcctgc
     1681 acttctttgt agttttgact gtttttgtgt cgtttaaggg aaaggacaag aatgactcaa
     1741 caagactttc ggacaaaagt agacaatacg gtttttggtg ttcgggctac agccttgatt
     1801 gtccaaaatc acaagcttct agttaccaaa gacaagggca agtattacac tattggaggt
     1861 gcgattcaag tcaatgaaag cacggaagac gcggtagtcc gtgaagtgaa ggaagaactg
     1921 gatgtcaaag ctcaagctgg gcagctagct tttgtggttg aaaatcgttt tgaagtggac
     1981 ggcgtttcct atcacaatat cgagtttcat tatctggtgg atttgcttga agatgccccg
     2041 ttgaccatgc aggaagatga gaaaaggcag ccctgtgagt ggattgactt ggataagctc
     2101 cagaatatcc agctagttcc agccttttta aaaacagccc taccagattg ggaaggccaa
     2161 ctaagacaca ttcatcttga ggaataggag agaaacatga cttatcattt tactgaagaa
     2221 tacgatatta ttgtaattgg tgcgggacac gctggggttg aggcttcctt ggccgctagc
     2281 cgtatgggct gtaaggtcct gcttgcgacc atcaatattg aaatgctggc tttcatgcct
     2341 tgtaatccct ctatcggtgg ttctgctaag gggattgtcg tacgtgaagt cgatgccctc
     2401 ggtggcgaga tggccaagac cattgacaag acttacatcc agatgaagat gctcaacaca
     2461 gggaagggac cagccgttcg tgcccttcgt gcgcaggctg ataaggaact ttactctaag
     2521 gaaatgcgca agacagttga aaatcaagaa aatctgaccc ttcgtcaaac catgattgat
     2581 gagattttgg tggaagatgg caaggttgtc ggtgtgcgta cagccaccca tcaagaatat
     2641 gctgctaagg ctgttattgt gacgacaggg actgctctcc gtggggaaat tatcatcgga
     2701 gacctcaagt actcatcagg tcctaaccac agcttggctt ctattaacct agctgacaat
     2761 ctcaaggaac tgggtctcga aatcggtcgt ttcaagacag gaacccctcc acgtgtcaag
     2821 gcttcttcta tcaattacga tgtgacggaa attcagccag gagacgaagt gcctaatcat
     2881 ttctcataca cttcacgtga tgaggattat gtcaaagatc aagtgccatg ctggttgacc
     2941 tataccaatg gtaccagtca tgagattatc caaaacaacc tccaccgtgc gcctatgttt
     3001 acaggtgtgg tcaagggagt ggggcctcgt tactgtccgt cgattgaaga caagattgtg
     3061 cgctttgcgg acaaggaacg tcaccaactc ttccttgagc cagaagggcg caatactgag
     3121 gaagtctatg ttcaaggact ttcaaccagt ctgcctgagg atgtccagcg tgacttggtt
     3181 cattccatca aaggtttgga aaatgcagag atgatgcgga caggttatgc tattgagtat
     3241 gatatggtct tgcctcatca gttgcgtgcg actttggaaa ccaagaaaat ctcaggtctc
     3301 ttcactgctg gtcagacaaa tggaacatca ggttatgaag aagctgctgg ccaagggatt
     3361 atcgcgggta tcaatgcggc tctgaaaatc caaggtaaac ctgagttgat tctaaaacga
     3421 agtgacggtt atatcggggt gatgatcgac gacttggtga ccaagggaac cattgaacct
     3481 taccgtctct tgaccagtcg tgctgaatac cgtctcattc ttcgtcatga caatgctgat
     3541 atgcgcttga ctgagatggg acgcgagatt ggccttgtgg atgatgaacg ctgggctcgt
     3601 tttgaaatca agaaaaatca atttgataat gagatgaaac gcctagacag tatcaaactc
     3661 aagccagtca aggaaaccaa tgctaaggtt gaggaaatgg gcttcaagcc gttgacagat
     3721 gcggtgacag ccaaggaatt ccttcgccgt ccagaagttt cttaccaaga tgtggtggcc
     3781 ttcatcggac cagctgcaga agacttggat gacaagatta tcgaattgat tgaaacagaa
     3841 atcaagtacg aaggctatat ttccaaagcc atggatcagg ttgctaagat gaaacgtatg
     3901 gaagaaaaac gcattccagc caatatcgac tgggatgaca tcgattctat tgcgacggaa
     3961 gctcgtcaga agttcaaact catcaatcca gaaaccatcg gccaagccag ccgtatttcg
     4021 ggagtaaacc cagcagatat ttctattttg atggtgtatc tggaaggtaa aaatcgtagt
     4081 atttctaaaa ctcttcaaaa atcaaaatga tacgtcgtcg gcttcttacg aatgagttca
     4141 aagcttggct ttgattcatc tccaacctcc catagttccc cgaactatgg gagctaactc
     4201 aagttatgca ttttcctagc cttctggtct gattttcatt gagttttaat ctcaaaagaa
     4261 agcatagaga aaaacagctc cgaagacggg gctgttttgt tgacttgtac tcaatgaaaa
     4321 tcaaagagca aactaggaag ctagccgtag gttgctcaaa gcactgcttt gaggttgtag
     4381 atagaactga cgaagtcagc tcaaaacaca gttttgaggt tgtagataga actgacgaag
     4441 tcagctcaaa acacagtttt gaggttgtgg atagaactga cgaagtcagt aacatatata
     4501 cggcaaggcg aagctgacgt ggtttgaaga gtattattct tcatctggtg tgaggatcat
     4561 cgggatgatg atcggttcac gttcggtatt ttcatagagg aaggggcgaa tagcgttgac
     4621 aatggcacca ttgacagatt gcacgctagc atccttattt ttcagtgcga tacgaatggc
     4681 attgaagagg atacgctggc tttggcgaat caagtctcca gactctctca tgtagacaaa
     4741 gcctcggctg aggatatctg ggccagacag aatcatctgc gatttgaagt caacagttgc
     4801 gactgccaga acgacaccgt cttcagatag atcgcgacga tctttgagga cagctgcgcc
     4861 aatttcaccg atacgatttc catcgacata gatatcttgg gcgttgaaat gacctgcgat
     4921 acgagctgag tcagcagtaa gggcaagcac atcgccattg ctcatgataa agatattgtc
     4981 tttctcaaca ccagtatcca ctgctagtcc agcgtggact ttttgcatgc ggtattcacc
     5041 gtggacaggc atgaagtatt ttggcttaat caagcggagc atgagttttt gctcttgctg
     5101 accaccgtgt ccagatgtat ggatattgtt cactttaccg tggataactt cgacaccagc
     5161 ttcagaaatg atgttaatca gcttgttgac gctagtagtg tttccaggga tgggactaga
     5221 agagaagata acggtatcac ctggttgtaa ttgtacttga cggtgggttc cgttggcgat
     5281 acgagagagg gctgccatag gctcaccctg actacctgta cagaggataa gaacttctcc
     5341 tgcaggataa tctttgattt catttggctc gataaaggtt cccttaggag ctttgatgta
     5401 gccaagatcg attccgttga caatggcctt ttccatagaa cgaccaaaga ccgcaatctt
     5461 gcgtccagtc ttaacagcag cttctgttgc ctgctggaga cggaagatat ttgaggcaaa
     5521 ggatgcaaag atgatacgtc cttcaatacc ttggataatc ttcataatgg actgaccaac
     5581 gactttttca gagttggtaa aggttggtac ttccgcattt gtcgagtcag acaggagaca
     5641 gagcacgcct tcttcaccaa gcgcagccat acgatgcaag tccgcaggtt ctccaactgg
     5701 agtaaagtcg aacttaaagt cacccgtaca gacgattttc ccttgaggag tatgaatgac
     5761 aatccccaaa ggctctggaa tagagtgagt cgttctaaag aaagttgcct tgagattttt
     5821 aaaggtcaac tcggtgttgt ggttgatttc gtaaagtttg gcgttgcgca agaggccgtg
     5881 ttcttcgagt ttcccacgga tcaaagccaa ggcaagcggt ccagcgtaga tagggacatt
     5941 tgcttgcttg agtaggaacg gaatcccacc aatgtggtcc tcgtgtccgt gtgtgattaa
     6001 aacagccttg acgcggtcga tattgtctac gatgtaagag tagtcaggaa tgacatagtc
     6061 gataccaagc aagtcatctt ctgggaattt aatcccagca tcgacgatga taatctcgtc
     6121 ttggtattca attccgtaag tgtttttccc gatttctcct agaccaccga tggcaaaaac
     6181 accgacttct tcaggtttaa gagtgtaggc catattagaa ctccgtaatt tcgaaggcgc
     6241 cagtttcttt ttcgtaatcg agcaatttgt cagacaagag ttcgatatat tcgatattgt
     6301 actctgggcg attttcttcg acaagttggc gagcagtgat acggccctca agttctgagc
     6361 tggcatcgat gtctaggtaa agcgcgcgtg ttgtttcacg gcgtgggcta cgttcttttg
     6421 tttcttgata aaaaactttg taaatcatat agttcctttc tatttacagg tcagcttatt
     6481 ccaaactttt agcagatatt tgcttgattt cattccattt tgtgtctaga ttgaccttga
     6541 ttcgttacaa ttatttcaat tataccacaa aatgaaaaat tagtaaaaga cggaaacgag
     6601 aaagttaggg gacgatttct tcggtaagcg tttgcaaaaa caaagaaaat gtgttatgtt
     6661 gataacggaa gtgaagttta ttacttgtca taattccata tagattttaa gtcaaggagg
     6721 ttgccctatg tataacttat ttgcttttgc tatcggagtt cgtttgctag cttttatcgt
     6781 ttttgttttg cgtttatgga ggaaatcttc tatttgccaa actggaacga tgacaaacca
     6841 agttcttgag gaaaattacc tttgtgactc tctactcgct ttttctcctc ctcgtgacct
     6901 atgtcgtttg gtttgtattt tactttggat taaatgctta gatgccctgc ttatgctggg
     6961 gttttttgtt tggggatgta gagatagtag atttacgaca cgaaaattcc accccatcta
     7021 tcaagatgag gtggtctttg catttttcta aaatgatatg acaatggaat tttcaaagct
     7081 tattattttt atgggagtca ttgttctgct caaaaataga gttgaagcat aaaaataaaa
     7141 caatacaaac agataaatcg aatggtaaag ggatggtagt aatgttcaaa tcattgagaa
     7201 tgctgagcaa actgtaagag atgaagacaa taaaatttat ccttctaaaa atgtgtttct
     7261 tatctagcat gacttaccaa actttttacg aaggtctttt ccaatggtat aacctgccat
     7321 aaataaagcg ataccaacac ctacaccaaa gccacccttg atttcttgca attccttatt
     7381 agaaatttca cgacagttgt tcaaatcttt catcatatta atctcctcct aaaaaataac
     7441 cagctgccaa accagaacct ataagtgctg ttccacctgc aatagctttc caagatactg
     7501 ctactccaaa gataaccaag ggagcgagac cgccatcaat atctgataat tcattttcag
     7561 ataaggataa aaattgattg tcaagaatgt caaaatttgt cattgaactt tcctcctttt
     7621 ttcttgttca cttttatatt cggaaaagaa aaggaaaagt gagcattttt ttaaattatt
     7681 tttagttaag tgagggcact cttgtctggg ggcaaagaaa attcccatgt gccatctttt
     7741 gtagtataat agtaagcaga caaaaagata ggaatgtgtt atgaaagtat tagcttttga
     7801 tacgtccagc aaggctcttt ctctcgctat tttagaggat aagcaggttc ttgccgagac
     7861 gacgattaat atcaagaaaa atcacagtat taccctcatg ccagccattg attttttgat
     7921 ggagagtttg gactggacgc ccaaggattt ggaccgaatc gtggtggcgg aagggccagg
     7981 tagctacaca ggcttgcgaa tcgcggtagc cactgccaag accttgactc atactctgaa
     8041 cattgagtta gttggtatgt ctagcctctt ggctctggtg ccatatcaac aagaaggctt
     8101 gttcgttcct ttgatggatg cgcgtcgcaa caatgtttat gcaggatttt atgaaaatgc
     8161 taaacctgtc atgccagaag cgcacctatc ttttgaagag gtgctagaaa aagtcaaggg
     8221 tgctagtcag gtaacctttg tcggagaagt tggccccttt gtggagcaga ttcaagaaca
     8281 cttgccaagg actaattata aagaaacctt gcctaatgca gccaatcttg ctcttttagc
     8341 ttgggacaag gaagcagact ccttgcatga ttttgtgcca aattacctca aacgagtcga
     8401 ggctgaggaa aactggctca agaaccatac cgagtctggt gagtcctaca ttaaacgcct
     8461 atgatagaaa tcaagcgaat tcaacaacag cctgacctag ctcaagccat ctacgctgtt
     8521 atggcagctg tttacctagt cagtccttgg actctggagc aaatccaagc agatctgtcc
     8581 caagaccaga cttggtatgc attggcttat gatggggcag aagtgattgg atttctagct
     8641 gtgcaggaga atctttttga agcagaagtc ctgcaaatcg ctgtcaaagg agcttatcag
     8701 ggtcagggaa ttgcgtcagc cttgtttgct caattgccga cagataagga gattttcctc
     8761 gaagtcagaa agtcaaatca acgagcgcaa gcattttaca agaaagaaaa aatggcggtc
     8821 atcgctgagc gaaaggccta ctaccatgac ccagtcgagg acgccattat catgaagaga
     8881 gaaatagatg aaggatagat atattttagc atttgagaca tcctgtgatg agaccagtgt
     8941 cgccgtcttg aaaaacgacg atgagctctt gtccaatgtc attgctagtc aaattgagag
     9001 tcacaaacgt tttggtggcg tagtgcccga agtagccagt cgtcaccatg tcgaggtcat
     9061 tacagcctgt atcgaggagg cattggcaga agcagggatt accgaagagg acgtgacagc
     9121 tgttgcggtt acctacggac caggcttggt cggagccttg ctagttggtt tgtcagctgc
     9181 caaggccttt gcttgggctc acggacttcc actgattcct gttaatcaca tggctgggca
     9241 cctcatggca gctcagagtg tggagccttt ggagtttccc ttgctagccc tcttggtcag
     9301 cggcggacac acagagttgg tttatgtttc ggaggcagga gattataaga ttgttgggga
     9361 aacccgtgat gatgcggttg gtgaggctta tgataaggtc ggccgtgtca tgggcttgac
     9421 ctatcctgca ggtcgtgaga ttgacgagct ggctcatcag gggcaggata tttatgattt
     9481 cccccgtgcc atgattaagg aagataatct ggagttctcc ttctcaggtt tgaaatctgc
     9541 ctttatcaat ctttatcaca atgccgagca aaagggagaa agcctgtcta cagaagattt
     9601 gtgtgcttcc ttccaagcag cagttatgga cattctcatg gcaaaaacca agaaggcttt
     9661 ggagaaatat cctgttaaaa ccctggttgt ggcaggtggt gtggcagcca ataaaggtct
     9721 cagagaacgc ctagcagccg aaatcacaga tgtcaaggtt atcatccccc ctctgcgact
     9781 ctgcggagac aatgcaggta tgattgccta tgccagcgtc agcgagtgga acaaagaaaa
     9841 cttcgcaggc tgggacctca atgccaaacc aagtcttgcc tttgatacca tggaataaag
     9901 agtggctctt tgtcaagtgt agtgggtagt cgaaaagctg caatctggag agtacgaaat
     9961 tcgtactctc ttttttgatg ttcaaagtca tcaaaatccg ttttttaaaa ttgttaaagt
    10021 tccggaaacc aaaggctttg cgcttgataa tcttaatcaa attattggtc gcttcaagtt
    10081 tagcgttgga ataaggcagc ttaagtgcgt tgataatctt atctctatcc cttaaaaaag
    10141 tccaaaagac cgtttgaaaa agcggatgaa ccgttggcag ttcttgctca atcaatccaa
    10201 agaaatggtc ggcattcttc tcttgaaaat gaaagagcag gagttgatag agttcgtagt
    10261 gaacctgtaa tccctcagag taagaaagca gcttatctcg tacttcccga tgggttaagt
    10321 gcattcgaaa cgtgggctga tagaatcgtt tctgacagag cttgaagcta tactggtgta
    10381 gtaaatcagt ccagtggact gatttagccc gagcctagaa acgaaaaagc gagggttcca
    10441 aaagcgcttg agcgcccgat actccaagga ttttcggtca aattggttca tgatttggat
    10501 tcgtactcgg ttcatagctc ggctcagatg ttggacaatg tggaagcggt caagaacaat
    10561 cttcgccttt ggaaagagtt gcttagcgag ccgataataa gggctgtaca tgtccatggt
    10621 gatgacctcg accagctccc gaacctctct ctgatagcgt tggaaatggt ttcgaatcac
    10681 cgcatgagtt cgcccgtcta aaattgcgag gatggatttg gactcaaaat cttgggcaat
    10741 gaagctcatt ttgctctttt tgaagctata ctcatcccaa ctcataactt ttggcaactt
    10801 ggtccaatcg gtttcaaact taaattccct cagttttcgg atgacggtgg aagttgagac
    10861 cgccaatctg tgggcaatct cagtcataga ctgcttttca aggaggagct gagcgatttt
    10921 ttgtctcacc atgttggaaa tctggcaatt tttcttgaca atggatgttt gagaaacgac
    10981 caccttaagg caattcttgc actgaaagcg gcgctttttg agatgcagta ccgtgggtaa
    11041 accctgacag tcgagaagcg gaattttaga ggctttctgg aagtcgtatt tgatcatctt
    11101 cccttgacaa tgaggacaag gaggagcggg ggaatccaac tttgcctgaa cgactagatg
    11161 ggtttggtat ttcagaacag acaagatttt gatatttttg tcttccaatc cgagcaaatc
    11221 tgtggtattc ttaagttgtt ccatatggac cctttctaat gagttggtta gacgcttttc
    11281 attataggtc atatggggct ttttttctac aagaaacgac cctataattc ctggggtggg
    11341 attacccact acagaaatta tagagccaaa gcattccaaa gtcttgtctg actctggaat
    11401 gttttctgtt cacagttgtt ttgtaactgc ctaataagta accgcgctat aacgaggtat
    11461 ctaccgagat tgtcaattct ccagtatact gttataaaaa acaaaactgg aggatttttt
    11521 tatgtcctcc catcgtccca tcgactgttc cgtagctgcc caataacgga gtatagtcgg
    11581 ctgaaacaag aataggacaa aagtgcctca agaaaagcat cgtaatttga caatattatt
    11641 ctgagatgtt tttgatgtaa gcccatattt tctcaatggg attatactcg ggtgaatagg
    11701 taggaagtgg taacagtcta tgccctgctc cttacacatg ttcattctgt gaaaccttgc
    11761 attgtccata atgataaggg atggtgtatc taaagtaggt agtaagaatt tttggaagca
    11821 agcttcgaaa aagtcactcg tcatcgtatc tttataggtc atcggagcca tagtatattg
    11881 aaacaaaaaa gggcattagt acttctataa cagtatcgca atctctggtg tgcgttgtct
    11941 cgatcttaat tcaaataatt atatcttctt ccagagagac taactgcctg ctcaaggctc
    12001 gatcatattt gagataaaaa taggtctcaa cccctgtctc ataaatataa ataggagtca
    12061 ggtagcttaa gtgattcaat tctttaagga accgatttac tttttctggg tcttgttcgc
    12121 agtaggtacg gctcttttta gactatatcc catagccttt agagcgtaat gaatagttgt
    12181 tggaggacag ttgaattcag cagctatttc agtcaaataa gcatcgggat gagtttcaat
    12241 atagatcttt aatttatctc tatcaacttt ttcaattaat agtggaagtt ttcttaaagt
    12301 tagtgtgttg aaacgttttt atacagtgct aaaatttgaa gtgtagtgca gatgtatttg
    12361 taatagtatt atagcaattc tttggagaag gtcgagacaa gagaaaatag gtatctttga
    12421 gatataagta tgatttacta taaaattatt gagttattca taaaaatttc tctatcaaat
    12481 atcataatgc gtcgtttaag gagatggtta caatgcaata tagttgtgga aaaataaata
    12541 ttaatatccc tgatggatat ggagacatta aggatatagt gttttcggct catattatag
    12601 ttaggtataa taatggacat tgtggaggta tagatccgca tataattgga ctttgtaaaa
    12661 agcagatcag aaggatgtct ccatatccta ttttgataat cgtatctaga gattcaaagg
    12721 ttattgatga ttataaaaat ttagatattg cctatgttga ttgtactcaa tgttcaaata
    12781 attttgaaac tgccttacac gttaaaaata ttttaaaatt attaaaaatc caacttatac
    12841 actgtcatgg ctactcaact aattattttt tatatatgtt aaaaaaactt gacaagaatg
    12901 gatttggaaa ggttaagaca gtgataacat gccatggatg ggttgaatat aacttaaaaa
    12961 agaaattctt gacttatttt gatttttgga catattctat gggagatgct tttatttgtg
    13021 tatctgaaac tatgaaaaaa agattggaga gtataataaa aaaataagaa gatagttgca
    13081 ataaataacg gaattaatgt atcaaatagc gatttagatg tagtaggtgt tcaagacttt
    13141 aaaaaagaat tttgtattcc aaataacaaa aaaatcattt gttatgttgg aaggttggat
    13201 ccagaaaaaa ggccggatag attccttgaa tttgcagaaa aattattttt agtcagagaa
    13261 gatgtgattt ttattatggc tggaaatggt agtatgtggg ctactttgaa agaaaaaatt
    13321 tgccatttga aatgtagaga taatttcagg ttacttggtg aaatctatcc agctactata
    13381 gtttaccaaa tatcggattt attgtatatt ccttctgata cagaaggaat acctatgtgt
    13441 gttttagagt caatgtcaca agaaactccg gttttagcta gtaatgttgg cgggttaagt
    13501 gaaattattg aacatagggt tgatggattt ttatttgaga aggaagatgt tgagggagtg
    13561 tgtgcttgtg ctaatttttt actcaatgat tctgagtatt tgaaatatat aggtgagaat
    13621 agtaaatcaa aaataagaaa acatttttct gtgcaaaaaa tgtttgtaga aaccatgaga
    13681 gtatatgatg aattattaga gaagagtagt catggatagg aatatagatc aagaattagt
    13741 aagtattata ataccaacac ataataggta tgaatctctg attagagctg tgaaaagttg
    13801 tttacatcaa agttataaaa atatcgaagt tataattatt gatgataatt atagtaatgt
    13861 aaatttaaga aataaaatta tccatcaatt tggctatacc agtcatagaa ttaagttaat
    13921 tttaagtaat gaagatttag gtgcaactaa tgccagaaac ataggtatca aaaattctag
    13981 aggtaagtat atatcatttt tagacgatga tgatgaatat atgccagatc gaattttaaa
    14041 gttgatggct tgttttaaaa agagtagaat gaagaattta gctttagttt atagttatgg
    14101 aataataatt tatccaatag gaaatatttt aatttattga gtttcaacga gagaatattg
    14161 gttacaaaga aatattattc tttaaacata aagcggttac tattaatagg agacaaatgc
    14221 aaggctttaa aagtaatcaa gaaggcaaga gaagaaaaaa tttttaacga atttcttttt
    14281 cgaaatatat gttattatat cattttggtt ttttctattg tatatatgac aactatgttc
    14341 aattaaaatt tagaaagtga gaaactattg tgtatactat tataaaatca aatataaaaa
    14401 aatttagttt attaacgata tttattgttg ctggtcaatt attgctaatt tatgcagcaa
    14461 ctattaatgc tctggtgttg aatgaattaa ttgcgatgaa tttagagcgg tttttgaaat
    14521 tgtcaatcta ccaaatgatt gtctggtgtg ggataatatt ccttgactgg gtagtgaaaa
    14581 attatcaggt tgaagtgatc caagagttta atctagagat tcgaaataga gttgccacag
    14641 acatctctaa ctctacctat caagaatttc atagtaaatc atcaggaaca tatctttcgt
    14701 ggctaaataa tgatgttcag actttaaatg atcaggcttt taaacaactt tttttagtaa
    14761 taaaaggaat ttctggtact atatttgcag ttgtgactct taatcactat cattggtcat
    14821 tgactgtagc caccttgttt tcattaatga ttatgctact tgtaccaaaa atctttgcat
    14881 cgaaaatgcg agaagttagt ctaaatttaa ctaaccaaaa tgaagctttt ttaaaatcta
    14941 gtgagactat attgaatgga tttgatgtgt tagcgtcctt gaatctttta tatgtattgc
    15001 ctaagaaaat taaagaagca ggaattttat taaagatggt tatacaaaga aagacaactg
    15061 tagaaacgtt agcaggcgct attagcttct ttctcaatat tttttttcag atatctctcg
    15121 tttttttaac aggctatctt gcaataaaag gaatagtgaa aattggtact attgaagcaa
    15181 taggagcact aacaggtgtt atttttacag cgctaggtga attaggaggt caattatcct
    15241 ctattattgg tacgaagcct atttttttaa aattgtattc aattaatcca attgagtcaa
    15301 ataaaatgaa tgatatcgaa ccaaatgagg tgaatagaga ttttccgtta tatgaagcaa
    15361 aaaatatttg ctataagtat ggagataaag aaatattaaa aaacttaaat ttttgttttc
    15421 aacgtaatga aaagtattta attttaggtg aaagtggaag cgggaaatct acattattaa
    15481 aattattgag tggctttttg agagattata gtggagaatt gcgattctgc ggggatgata
    15541 taaaaaaaac ctcctattta aatatggttt cgaatgttct atatgtagat caaaaagctt
    15601 atttgtttga aggtacgatt agagataata ttttattgga agaaaattat actgatgaag
    15661 aaatactaca gtctttagag caagttggtt tgagtgtaaa agattttcct aataacattt
    15721 tagattatta tgttggtgat gatgggagat tactgtcagg agggcagaaa caaaaaatta
    15781 ctttagctag agggctaatt agaaataaga aaatagtatt aattgacgag ggaacttctg
    15841 ctatcgatag gagaacttcg ttagcgattg aacgtaagat attagataga gaggatttga
    15901 ctgtcattat tgttacccat gctccgcatc cggaacttaa acaatatttt actaagatat
    15961 atcaatttcc aaaggatttt atttaagaat ataggggagg gaaacatgag attctattgt
    16021 gaagcttatg aggtaattac tgaagagaaa aaagtatact ttaatgatat tgagttagaa
    16081 gttaagtatt cctctgtcga agaattgttt ataatatgtg agaaattatt agataagaaa
    16141 aaagtatcat ttttttatgt atatgagaaa cccttaaggt atctgttatt tgactatata
    16201 tttctactag ttctagctaa aaaaaatatc ccaatcttag atggagtttc caataagcaa
    16261 gttgatccaa cgttgctgca tcacttttct ttggaaattg aaaagaattt tatcgatttt
    16321 tgctataaaa atatggatct catcctaaaa actcaaagta tatctttgtg tcatagagaa
    16381 gagcttatta ttgtagatgt ttcagatgac tctaaatttg gtgtttttta caagcgtttt
    16441 agaacactgg ttgataaaaa taacggaaaa tatgtttgtg tttataattt cagtcgtgtt
    16501 tcagatatac tgcaaaactg gaaaaattat tgcaatcgaa aattttcggt tacgtttact
    16561 gaaagccaat ttgaattatt taagctttta tataatcaaa aaaattttaa aacaatttcg
    16621 ttgctatttg gaaaaaaatt gttgctggag gaattatcta ttatagcgat cttactaata
    16681 tagaatactt ttgtattttt tggtgggata gtatgtttgg gaaagattct attggaaaat
    16741 acgtatatgt agaagagatt agtagatgtc attttttaga tagaaattat tctttttgtt
    16801 atggtttaca agattataaa agtaaactta ttaaatattt tttagaatag ttaatctatt
    16861 cgagagagat aaagaaatat ggaaaatact ttattgaata tcacaggaag cttcgatatg
    16921 gaaactagga atctaattag ttattcttta actgatatct ttgaaacaga taaaataaga
    16981 attgaacttc ttggagaaat ttattataaa aatataaagt tggaattgca tgaattcgct
    17041 ggattgtata agatttatgg aattagctta ataaagaata ttaccggaat gtttttaatt
    17101 ataatttttg atacgaagac aaaagaatta aaaatttttc aagatataac gacttcatac
    17161 tttaatttat actatactgt ttatggaggt gtgttctata tatagtacat ctttaaagaa
    17221 agtgatgaag ttatctcatg ttcccgttac cttaaataac aaaaaaatac aagaatttat
    17281 gagaaatgga tttattttag attcaaatac tttagtaacc gaaattaata aattagaata
    17341 tttctcttac atttctgtaa ataatactct tcgtatatgt ggtattgatt ataatgattc
    17401 aaacaatttt actaaagaac aagtattaaa gaattgggac tctatgctac gtgaatctat
    17461 attaagagtg tatagtgaag caggagaggc taatattaca ctatcatctg gttttgattc
    17521 aaattatata ttatatacat tagcgaatta tacgaattct tcaattaatg cattttgcat
    17581 aggaggagaa aaaggaatta atgagattcc tgaagtaact aaaattgcaa aattttatgg
    17641 tataaattta ttagttgata ctgtaatgag cccaagattt agaatatttt cccgatatag
    17701 tatggagatt ggaaggaagt ctctttgaat gtggtgtcat actgcagtac tatttaggca
    17761 ggttgttgtt ccaaaaaggg aacacaagta ttctttgtgg cgagtcagcg gatgaaataa
    17821 tgacttttaa gtatcattct gtgaactaca atcaattttg taatgataaa cagaagtcag
    17881 tatattttag ttattccgac tatccatttt atgttacaaa ttcaattgtt ttaaagaaaa
    17941 atagcctact tttgcatagt tttggcattc atcctagata tccatataaa atgtctgaga
    18001 ttgttgaaat gtctaaaaaa atatcagatc taaacgataa aaaagaattt cacaaaaaga
    18061 actgtgagtt gaggtttcaa gatagtgttc ttgataacat aaatagtgtc ccgggtacaa
    18121 ctcatttatt tagttgttta aatattcaaa cattagtaaa aattatttta tatatttttc
    18181 gatacaacag ttgtatgaaa atatttaatt ttagagataa agagcttatc ttttttaata
    18241 agattgtaaa tgggctgata caaaatattg aggagaattt agaggatgat attgaaagga
    18301 tattgaaata tttatatata tgtttattta acgaaatatt cattattaag aataaggtga
    18361 atttttttga tgatgtggaa tttaatcaga cacttagtga gtttttagat aaattgtaga
    18421 gggaatggtt atgagtgaca atactaagta tatcttttta tctccacatt tagatgacgc
    18481 aattttttcc tgtggtgatt atatttcaaa attaacttca gaaggagaaa ttgtacttgt
    18541 tattactata ttttctggtt accctttgag ccaacagcta cagccctctg ctaagcaatt
    18601 tcataagttg tgtaaccttg ggaaatatcc gattgaagaa aggaagaaag aagacaggtt
    18661 agcttgtgaa cgtctacaat gtgattttag acacttatcg tactatgaat gtctctatag
    18721 gaaagataga aatggcaatt ttctataccg tcatatctat agtaaattaa aaaatgagga
    18781 cacattaaag aatgatatca taaaagagct gttaatgcat ttagacgaca aatgtgtcgt
    18841 atattgtccg ctttcacttg gtgaccatgt tgatcatgtt tttgtgaata gtattggaag
    18901 ggcgcttgaa tttatgcgtt ataaagtaat atattatgag gacttcccat atgtaagtga
    18961 tagtagtatg gttagttata tgggaaaaac taaagaatta aaaatgtatc aagaggaact
    19021 tgatgaaaaa cattatattg atagaatatc atcaatattg tgctataaat ctcagatttt
    19081 gataatctgg aaatcagttg aaaaactttt aaacaatatt aaagagttgt atttaaggaa
    19141 tggggcagct tattctatta gattttggat taagaaataa ggaagtagtt ttatgaatat
    19201 agcagtaatt ggtttggggc atgttgggct ggcctacgcg ttactatttg catctaaata
    19261 taaagttgtt gcatatgata tagattctgt aaaaataaat aatttaaaaa agggcactct
    19321 tccatctaaa aatgaagagc ttatgaagtt tttttgcgag aataacttaa atattacttt
    19381 ttttgataca ttttctgaaa ttaaaaataa tattgattat tatattattg cgcttccgac
    19441 agattatgat gagaaaattg gtagttttaa tacatatgaa atcgaacaaa cggtatcgaa
    19501 gattctgagg gtaaaaccta atggaaagat tattttaaag tcaacagttc cgatcggctt
    19561 ttcaaacaaa ttaaaaaggc tgtttgatac aaaaaatatc atttttgtcc ctgaattttt
    19621 gagagaaggt tgttctatat atgataattt atatccaagt cgcatagttg ttggagatga
    19681 gacagttgaa ggaagaaaaa ttgcagagtt gttcctttcg attagtactc atagtactgc
    19741 caatattaaa aatgttatgt tagtttctcc tactgaagca gaagcaatta agcttttttc
    19801 taacacattc ttagctctcc gtgttgcttt ttttaatgaa ctagattctt ttgctgagag
    19861 gagaagttta aatgctgaag ttgtaataaa aggtgtttgt ttagatccaa gaattggaaa
    19921 tttttataat aatccttctt ttggatttgg aggatattgt cttcccaaag atactagaca
    19981 attaaaaaaa gaatttatag aaataaatgc cccagtgata gaagcgattg atatttcaaa
    20041 cacaaataga aaacagttca tagttaaaca aatattggaa cgaaagccaa agatagtagg
    20101 aatatataaa ttggggatga aatataattc agataattac aaagagtcag ctattttaag
    20161 tataattaat gaactattga ttgtcggtat aaaaatttta gtatatgaac caaatttaaa
    20221 cgttagtata gataacgtaa tttttgaaaa gaattttgaa ctatttataa aacaaagtga
    20281 tctaattgtt gcaaatagat gggatagggg ccttgaagct tataaagata aagtttacac
    20341 aagggggatc tggataagag attaactatt gatattaaaa aggcaataat ttataaaatt
    20401 tgtacaaaaa aatgttaaat tttcacattt tcatagtata ctgtttaata gaaagtaggt
    20461 tctttgtaac cgctccatta taaaatcctt tcactcttcc ggtatactat taggaaaaac
    20521 ataactggag gatattttga gctcacacct catcgttcca gtggctgttc cccaagctcg
    20581 tgtactgccc aaaaaagtta gacattctat ttagaacgag gattgagttc tgtattgtac
    20641 aaggctcggt ccttttagag tcagcttaag gctggctttt tcaatcacca aagtgtcaga
    20701 atgttttgac aaatgaacac aaataatgat ataatatgca aaagctagga ggtggtagga
    20761 tgattgaaaa aatggaactg ggggaatttt acaaggaatt gcgcttggcg agaaagctca
    20821 agcagtcaga tgtggcttgt gctggactaa cagcctctca gttgtccaag tttgaactag
    20881 gacagtctat gctgtctgca gacaagctga tcctagccat ccaagggatc aatatgaatt
    20941 ttgatgagtt tgggcacaaa ctcaacaact atcaagaatc tccacatatg cgaattggta
    21001 gaagggttgt ggattgcttt tcccatcagg atatagctgc tttagagcag ctattggagg
    21061 aagtcgatca agaacagatg gcgcagacct atcgtcgttt gaatgccatt gtgattaaaa
    21121 atgcactcca ttccttagat aaaagctacc cgctaacaga ggaggatagc gagtttttga
    21181 ctacctacct ctacgctatt gagtcttgga cctggtttga actctatctt ttttgcaata
    21241 ctatgccctt cttgagcaat caagatctga tctttttatc aacctcctta ctcgaaaaat
    21301 ccaaggaatt taaagagtta gtacacaatc gatggtatat gaaaagtggt tatcttaata
    21361 tcatctcaga acttatggag cgcaagctat tttcttatat tccaatcttt gaagctgagc
    21421 tggagcgcat gctccgtcca tacgatgttt ttgaaaaagt attgtggcag tttttaaaga
    21481 aaatgcagat ttttcttcaa accaaaggaa gcaatcaaaa agagattgaa cactttatcc
    21541 aatctctgca agtattagaa aatccacaat tgacagccct ttttgaattg cgtttgcagc
    21601 aatacaaaga gcttatcgat tagttagaaa tgggaaaaag ataataatat cagcaacgat
    21661 cgtcaataat gttaaaactt gtttcttcat attacttccc tcctcattag taataacttt
    21721 attataccag ggaaataatc aaatctacca aaatcgcaaa tctgaaattt ctataagaaa
    21781 aaatatcaaa tatgcgattt tctaaaataa gccaatttcc gtgttatact gtccttgtaa
    21841 aacatttgaa gcaaatccta ggtcgcagaa gtggtttaca aatgaagata attgaaggag
    21901 tgtaaaagat gttaaattta caatttgcag aaacaatgga attgacagaa gctgagttgc
    21961 aagatgttag aggaggcaac ctcgtaaatt ctatgggagg tggtggaaga agtggtatat
    22021 ctggttgggg cgtcccagga atttaccctg gttggggcaa tcaagggatg agtcctaatc
    22081 gtggagcttt tgattggact atagatttag cagatggatt gtttggccgc cgtagaagat
    22141 aggctcttat aggagataat aggatgaaga aaatgaaaga agtgaaattt cacctagcaa
    22201 ctggcttgtt gattttgact tattacctca tttttaatgt cacatcagac ttagatttta
    22261 tggttgcttt gtctgataat atgtactatg tgttccaagt tttattggta cttattctgg
    22321 gaactatagc tacaattgct tttgtcaaaa gtgaacattg gaaagagtgt ggtcgtttcc
    22381 agtttcgttg gtcttacctg ggtgttttcc ttctttcttt tttcttattg ttcgtgtggg
    22441 caaatctaac aacctatatc tttcctcgta cccagaatgg aagtacagtc gtagaagtag
    22501 ccaccagttt aacaggaatt agctattttg ttacgcgaat actttatact agtattatcg
    22561 cacctgtatc agaagaggtt gtttgtcgtg gtcttttgat gacaagttta tctaaagtta
    22621 agagatacta tcttgatgtt cttgtttccg ctgccatatt tggcgctatg catgttttgc
    22681 agtatggttg gataacgaca gatttcataa agtattttgg aatgggcttg atattttgta
    22741 tgatgtttcg ctacacccga tccatctatt gggctatagc tctgcatgct tcatggaata
    22801 gcttcttact cattgttact ttattggtat ttggatatta gaaaggtgat atatgaaaaa
    22861 gataatctca caccgctact ttattatagt ttttctacta gttattgctg accagaagtt
    22921 cagtgtttta gttttacgca gcgaccttgt tgctgggcta tctgactttg cctattatct
    22981 gtcggatatg atgttgaatt ttcttgtggt tttatttgct cttattgcta tgatttggtc
    23041 ggggaaatgg cagaaaatca atagtagaaa gtttaaagga tcctatcttt tctattcctt
    23101 cctagctctg cttgcttttg ttgcttggaa ttttgtcacc ttttttcttt tcccacctac
    23161 tcgaaatgaa atttcttatc aacatgctgc tcctactttt acaggagcta cggcattttt
    23221 gatgtatttt ttttatcctg tgattgcagg tcccattttt gaagacatga tttatcgtgg
    23281 attggtgatg acagctctgg aaaaaggaaa gaaatggggg ctagatgtac ttggttctgc
    23341 tattttattt ggggtctcgc acattagtaa tcacggttgg gtcttgacag actttttcgt
    23401 ctatatgggt ggcggactta tatttgcagt cttatttaga atgacaaagt ccatttattg
    23461 gcctattggg ctgcatatag tctacaacgg cattggtcag cttttgatgt tactgtaatt
    23521 ttggttgtta gtagtatcgc ggtctatttc tggggaaaga ttcccatttg aacttaagaa
    23581 ggagttgtga tgaaagtatt tcttcaaaat agagatttta ggcaattaac tatcaaccag
    23641 tggatttcaa cgcttgggga tacgattttt tatctggcct tcctgaatta tgtggcagat
    23701 gcgtcttttg cccctttggc gattttactt atcacgattt cagaaaccct tccccaagtt
    23761 ctacaaatct ttctgggagt tttggcggat tttcaacatc atcgtgtctt gaaatacaca
    23821 gtcattagtt ttacaaaatt tttgctttac tctatagtgt ccctatcgct ttcagggcag
    23881 tctttttcct tgttgctagt aacctttatt tgtctgctta acctcttgtc tgacacattg
    23941 agttattttt caggcgccat gctcactccg attttcatta gaattattgg gcaagaccat
    24001 ctggcagaag ctattggatt taaacagtca actgttagtt tagtgaaaac aatcagtaat
    24061 atcctaggag gagtcttact aggcattcta tccatccagt ttatttcctt actgaacgct
    24121 cttacctttt taatcgcatt tttaggtatc ctcttcataa aaactgacct cttgaaagta
    24181 gaaaaaacga ttagctatca agaaggactc tctgtaaaat ccttttgcca gcatttgctc
    24241 caatcatcga aattgatatg gaatatgaat aaggtgctct tggttttgtt tattatctct
    24301 actagtcaag cagtgataaa tgttacggtt cctatttcca ctctattttt aaggaaccag
    24361 ccctttttga atttacaaac tggtcaatct cttgccttgt tagccacact agaattatca
    24421 gcccttattt tgggaagtct gatgagtggc tatctgcaac ataccatttc cataaaaata
    24481 gccctgtatg cttcactcct actccaatta ctactcctag tgggctttgc gacagctcat
    24541 tttggcttga ttctgatctt tagctttttg gatgcctttt tcgcgggtat tctctctcct
    24601 agattgcaag aactcgtctt taaacaaata cctgaggagt caatgggagc agttcaatct
    24661 tctatcggtg ccattacggt tgttttacct agcttattta caatagcttt gggaaccatt
    24721 gctactagct ttggaactct ggcagttagc tttgttttat tactatttct tctagttgcc
    24781 tttgtcatgc ttctgaatat tcgtgaaagt atttagtgga gaatttctat aatatatgtt
    24841 tgagactgga ttgccagtct ttttatgatg gtcaaaatca acagactttt tctcttttct
    24901 gaatgtgtta tagtagactg aatctaaaat agtacgaaat aattgctaaa acatttatag
    24961 aaattaattt tactttccca atcgatttgt tctcatctta tttcaatctg ctatataata
    25021 gtccatgctg tggctggatt cttttcagcc tacttatact cttcgaaact ctcttcaaac
    25081 cacgtcagct tcaccttgcc gtaggtatgg ttactgactt cgtcagttct atccacaacc
    25141 tcaaaacagt gttttgagct gacttcgtca gttctatctg caacctcaaa acaatgtttt
    25201 gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta ttattaagac
    25261 aatatgagga gaaagatgaa agaaaaagga ttttaggagg gggcgcaggc agccatgcca
    25321 acggctcttg gctatgtcag tatcggcctg gcctgtggga ctatcggtgc gccctatgtg
    25381 acacctgttg agatgggctt gatgagtctc tttgtttatg ctgggagtgc ccagtttgcc
    25441 atgttggcac tgattgtggt tcaagctcct gtggcagcta ttgctatgac ggtttttcta
    25501 atcaacttgc gtctcttttt gttgagttta cacgcatcga cttatttccg tcataccagt
    25561 ctttggtaca atatcggtat gtctagtatc ttgacagatg agacctatgg cgttttgatg
    25621 ggtgaattgg cccatacaga caaggtaaat cctatgtgga tgcacggaaa caatcttaac
    25681 agctatgtgg cttggtttgt ggggacagta gtcggaacgg ctctgggtgg cctgctacca
    25741 aatccagaaa tctttggctt ggattttgcc ctggttggga tgtttattgg tatttttgct
    25801 tcgcaatttc agattatgca aagacggatt cctgtccgca atctgctcat tatcctagca
    25861 gttgttgcgg tgtccttctt tttgctcttg acagtggtgt ctcagtcact agctgttctg
    25921 tttgcgacgc tacttggttg tagcatgggg gtggttttag atggtcagta agtatctttt
    25981 attagcagtt attttctctg acttggtgac ttggattctc cgtatgattc ccttcatctt
    26041 agtcaagtat aagggcttgc ctgcaatcgt tgagcgtttt ttgaagttct tgcccgtttc
    26101 cattatcttt gccttgattc tttcaagcgt agtgacaggt aaggttggga gccttcctca
    26161 aattaaatgg ctagacttct tagccgtctt tccaacagct tgggtagcct ttcgctaccg
    26221 caatctagtc ggaacagttc tctttggagt agtcttgatt gccgtcttgc gtttggtctt
    26281 ttaaatcagc cataaagaaa acctatcaca gatatatata tcatataatg gtgtaaatga
    26341 tttttttctg ttaagattat aaggtattct attttggagg aaatgacatg aaaaaaatcg
    26401 ttaaatactc atctcttgct gccctagggc ttgttgctgc aggtgtgcta gcagcttgct
    26461 ccggtggtgc taagaaagaa ggacaagcag ctagcaagaa agaaattatt gttgcaacta
    26521 attcttcacc aaaaccattc aactatgaag aaaatggcga attgactggt tacgagattg
    26581 aagtcgttcg cgctatcttt aaagactctg ataagtatga tgtcaagttt gagaagacag
    26641 agtggtcagg tgtctttgcg ggtcttgacg ctgaccgtta ccaaatggct gttaacaaca
    26701 tcagctacac taaagaacgt gcggagaaat acctttatgc agccccaact gttaaagacc
    26761 ctaacgttct tgtagtcaag aaagacgatt ctagcatcaa atcgcttgat gatgttggtg
    26821 gaaaatcaac agaagttgtt caaggaacaa catctgctaa acagttagaa gactacaaca
    26881 aacaacactc agataatcca actatcctta actatactaa agcaaactta caacaaatca
    26941 tgggccactt gagcgatggt cagtttgact acaagatttc tgataaaatc actgttgaaa
    27001 cagtcatcaa gaaccaaggt ttggacaact tgaaagtcat cgatcttcca agcgaccaac
    27061 aaccttacgt ttacccactt cttgctaaag gtcaagatga gttgaaaaca tttgtagaca
    27121 aacgtatcca agaactctac aaagacggaa ctcttgaaaa attgtctaaa caattcttcg
    27181 gagacactta cctaccggca gaagctgata ttaaataatt tcttgaaatc atccattctg
    27241 agtaagatgg gtgatttttc agttcgctac cgcaatctag tcggaacagt tctctttgga
    27301 gtggtcttga ttgccatctt gcgtttggtc ttttaaatta cccataaaaa aaacttatca
    27361 cagagataga tatcatataa tggcgtaaat gctctttttc tgttaagatt ataaggtatt
    27421 ctattttgga ggaaatgaca tgaaaaaaat cgttaaatac tcatctcttg cagcccttgc
    27481 tcttgttgct gcaggtgtgc ttgcggcttg ctcaggtggt gctaagaaag aaggacaagc
    27541 agctagcaag aaagaaatca tcgttgcaac caatggatca ccaaagccat ttatctatga
    27601 agaaaatggc gaattgactg gttatgagat tgaagtcgtt cgcgctatct ttaaagattc
    27661 tgacaaatat aatgtcaagt ttgaaaagac agaatggtca ggtgtctttg ctggtcttga
    27721 tgctgaccgt tacaatatgg ctgtcaacaa tcttagctac actaaagaac gtgcggagaa
    27781 atacctctat gccgcaccaa ttgcccaaaa tcctaatgtc cttgtagtga agaaagatga
    27841 ctctagtatc aagtctctcg atgatatcgg tggaaaatcg acggaagtcg ttcaagccac
    27901 tacatcagct aagcagttag aagcatacaa cgctgaacac acggacaacc caactatcct
    27961 taactatact aaggcagatt tccaacaaat catggtacgt ttgagcgatg gacaatttga
    28021 ctacaagatt tttgataaaa tcggtgttga aacagtgatc aagaaccaag gtttggacaa
    28081 cttgaaagtt atcgaacttc caagcgacca acaaccgtac gtttacccac ttcttgctca
    28141 gggtcaagat gagttgaaat catttgtaga caaacgcatt aaagaactct acaaagacgg
    28201 aacgcttgaa aaattgtcta aacaattctt cggagacact tatctaccgg cagaagctga
    28261 tattaaataa tttcttgaaa tcatccattc tgagtaagat gggtggtttc tcagttttta
    28321 gggatatagt tttaaactat atatctgact atctaataac aatttgtgaa atcaaacaaa
    28381 ttgtgagata ctagtacggt attattttta aggagaaaga atcatgaaaa tcaaaaaatg
    28441 gcttggccta gcagcccttg ctacagtcgc aggtttggct cttgcagctt gcggaaactc
    28501 agaaaagaaa gcagacaatg caacaacgat caaaatcgca actgttaacc gtagcggttc
    28561 tgaagaaaaa cgttgggaca aaatccaaga attggttaaa aaagacggaa ttaccttgga
    28621 atttacagag ttcacagact actcacaacc aaacaaagca actgctgatg gcgaagtaga
    28681 tttgaacgct ttccaacact ataacttctt gaacaactgg aacaaagaaa acggaaaaga
    28741 ccttgtagcg attgcagata cttacatctc tccaatccgc ctttactcag gtttgaatgg
    28801 aagtgccaac aagtacacta aagtagaaga catcccagca aacggagaaa tcgctgtacc
    28861 gaatgacgct acaaacgaaa gccgtgcgct ttacttgctt caatcagctg gcttgattaa
    28921 attggatgtt tctggaactg ctcttgcaac agttgccaac atcaaagaaa atccaaagaa
    28981 cttgaaaatc actgaattgg acgctagcca aacagctcgt tcattgtcat cagttgacgc
    29041 tgccgttgta aacaatacct tcgttacaga agcaaaattg gactacaaga aagcactttt
    29101 caaagaacaa gctgatgaaa actcaaaaca atggtacaac atcattgttg cgaaaaaaga
    29161 ttgggaaaca tcacctaagg ctgatgctat caagaaagta atcgcagctt accacacaga
    29221 tgacgtgaaa aaagttatcg aagaatcatc agatggtttg gatcaaccag tttggtaata
    29281 agaaacaggg aggtgggaga gaaaattcca cctcttgctt ttgtatagag tatagattgt
    29341 aaagaagact attcgttcat agaaaggtag agagaatatg gtttttccta gcgaacaaga
    29401 acagattgaa aaatttgaaa aggatcatgt agtccaacat tattttgagg ttttgcgtac
    29461 cttgatttct aagaaatcag tctttgccca gcaggttgga ctcaaggaag tcgcaaatta
    29521 tctgggtgag attttcaagc gtgttggagc tgaagtggag attgatgaga gctatacagc
    29581 gccctttgtc atggcacatt tcaagagttc gcgtccagat gccaagacct tgattttcta
    29641 taaccactat gacactgtgc cagcggatgg ggatcaggtc tggacagagg atccttttac
    29701 gctttcggtc cgcaatggct tcatgtatgg gcgtggggtt gatgacgaca agggtcatat
    29761 cacagctcgc ttgagtgctt tgagaaaata tatgcagcac catgatgatt tacctgtcaa
    29821 tatcagcttt atcatggagg gagcggagga atcggcttca acagacctag ataagtattt
    29881 ggaaaagcat gcagacaaac tccgtggggc ggatttgttg gtctgggaac aagggaccaa
    29941 aaatgccttg gaacagctgg aaatttctgg tggcaataag gggattgtga cctttgatgc
    30001 caaggtaaaa agcgctgatg tggatatcca ctcgagttat ggtggtgttg tggaatcagc
    30061 tccttggtat ctcctccaag ccttacagtc tcttcgtgct gcggatggcc gtatcttggt
    30121 tgaaggcttg tacgaagaag tacaagagcc caatgaacga gaaatggcct tgctagaaac
    30181 ttatggtcaa cgaaacccag aggaagttag tcggatttat ggattggagt tgcctctctt
    30241 acaggaggag cggatggcct ttctaaaacg tttctttttc gagccagcgc ttaatatcga
    30301 aggaatccag tctggttatc aaggtcaggg tgttaagact attttacctg cagaagccag
    30361 tgccaagcta gaggttcgtc tggttccggg cctagaaccg catgatgttc tggaaaaaat
    30421 tcggaaacaa ctagacaaaa atggctttga taaggtagaa ttatactata ccttgggaga
    30481 gatgagctat cgaagcgata tgagcgcacc agccattctc aatgtgatcg agttggccaa
    30541 gaaattctat ccacagggcg tttcagtctt gccgacgaca gcggggacag gacctatgca
    30601 tacggtcttt gatgccctag aggtaccaat ggttgcattt ggtctaggaa atgccaatag
    30661 ccgagaccac ggtggagatg aaaatgtgcg aatcgctgat tattacaccc atatcgaatt
    30721 agtagaggag ctgattagaa gctatgagta gagatattat caagttagat cagatcgatg
    30781 tgacttttca ccaaaagaag agaaccatca cagcggttaa ggatgtgacc attcacatcc
    30841 aagaagggga tatctacgga atcgttggat attctggagc agggaaatca acccttgtac
    30901 gggtgattaa cctcttgcaa aaaccatctg cagggaaaat taccattgac gacgatgtga
    30961 tttttgatgg taaggtcacc ttgacggcag agcagttgcg tcgtaaacgt caagatatcg
    31021 ggatgatttt ccagcatttt aacctgatga gccaaaagac agcagaggag aatgtagcct
    31081 ttgcccttaa acactctgga ctcagcaagg aagaaaagaa ggctaaagta gctaagttgt
    31141 tggacttggt tggtttggca gatcgtgctg aaaactaccc ttcacaacta tctggagggc
    31201 aaaaacagcg tgtggcaatt gcgcgtgcct tggccaatga tccaaaaatc ttgatttcag
    31261 acgagtcaac ttctgccctt gatccgaaga caaccaagca gattttggcc ttgttgcaag
    31321 atttgaacca aaaattaggc ttgactgttg tcttgattac gcatgaaatg cagattgtca
    31381 aagacattgc caaccgtgtt gcagttatgc aggatgggca tttgattgaa gagggtagtg
    31441 tgcttgaaat cttctcaaat cctaaacaac ctttgactca agactttatc tcaacagcta
    31501 caggtattga cgaagccatg gtcaaaatcg agaagcaaga aatcgtggaa cacttgtctg
    31561 aaaacagtct cttggtgcaa ctcaagtacg ctggagcttc aacagacgag ccacttttga
    31621 atgaattgta caagcattac caagtaatgg ctaatattct ctatgggaat atcgaaattc
    31681 tcgatggtac tcctgttgga gaattggtgg tggtcttgtc aggtgaaaaa gcagcgttgg
    31741 caggtgccca agaagccatt cgtcaagcag gtgtacaact aaaagtattg aagggaggac
    31801 agtaagatgg aatcattgat tcaaacctat ttaccaaatg tctataaaat gggttgggct
    31861 ggtcaggcag gctggggaac ggctatctac ttaactcttt atatgacagt tctttccttc
    31921 attatcggag gcttcttggg gctagtggca ggtctctttc tcgtcttgac agcgccaggt
    31981 ggtgtcttgg agaataaagt cgtattctgg attttagaca aaattacctc aatttttcgt
    32041 gcagttccct ttatcatcct cttggcaatc ttgtcaccac tttctcactt gattgttaaa
    32101 acaagtatcg ggccaaatgc agcccttgtc ccactttctt ttgcagtctt tgccttcttt
    32161 gcccgtcagg tgcaggttgt cttggctgaa ttggatggcg gtgtcattga ggcggctcaa
    32221 gcgagcggag cgactttctg ggacatcgtg ggtgtttacc tatcagaagg tcttccagat
    32281 ttgatccgtg tgacgactgt gaccttgatt tcccttgttg gggaaacagc tatggccggt
    32341 gcggttggag ctggtggtat cggtaacgta gccatcgctt atggatttaa ccgctacaat
    32401 cacgatgtga ccatcttggc aaccatcatt atcattttga ttatctttgc aatccaattc
    32461 ttgggagatt tcttgactaa gaaattgagc cataaataaa aaagagccgc gtggctcttt
    32521 ttaactgatc agattttctg tgcaaatttt ttactcaagg cttgtccaat caaggcaccc
    32581 actagggctc cgatgacaat acttgcgata aatagaagga cagttccagg gtttggagcg
    32641 accatgatgc ggtcgatata ttcttgggat tttcctcttg ccagaagagt agccatatag
    32701 gctttgggcg caatccacat aagcaagatt ggtcctgttg tactaaaggc gaaaataatg
    32761 aaagaaagga agttctttgt tttgtccttg tattttccta aatgagctac tccatctgct
    32821 aggaggccac agataattcc aggaaggaag gaaccagcac cgtgtttagt tcccaagaaa
    32881 aagagggcaa tgacaaggcc gatagtggta atggctccaa agcgcggaac ttttgcgact
    32941 aggatcatat agacgctacc gccgacaagg gcagtaaagg caggcgcata aaacatgttt
    33001 ccagtttggt caaagagatt gcccaaaagg acaccaatcc ccatgcagag gaagtaaaga
    33061 actgcaaaaa gcagtgtagt taagatagat ttcttcatga attgtctcct gataattttt
    33121 tcacaattct cattttacca tggtttggtg ggattgtaaa tggatactag aagtttttga
    33181 aaacgcttga aatatgatat aatggtttca tagttatttt taggggaata tcatgggtag
    33241 atttttagac tttgtcttta atcgtttctt tttagggatg attgcgacag ccttcttttg
    33301 gctattaact ttagcaggag ggattatcct tggtctagcg ccggctagtg ccaccttgat
    33361 gagcttatat gcagaacatg gttatagctt tcgggaatac agtttgaagg aggcttggtc
    33421 tctttacaag caaaattttg tctcaagcaa cctgattttc tatagctttt taggtgtggg
    33481 tctagttttg acctatggtt tgtatctctt ggtgcaattg cctcatcaga ctattgttca
    33541 tttgattgcg acccttttga atgtcctagt agttgccctg atctttttgg cttatacagt
    33601 atctttaaaa ttacaagttt attttgcctt gtcctatcga aatagtctca aattatcctt
    33661 gattggcatc tttatgagtc tagcagctgt ggccaaggtt ctccttggga ctgtgctact
    33721 tgtagcaatt ggttactata tgcctgccct gctatttttt gtaggaattg ggatgtggca
    33781 tttctttatc agtgatatgt tggaacctgt ctatgaaatc atccatgaaa aattggcgac
    33841 aaaatagaat gaagcagttt tggctacata cgcttctaag aacctatagt tcagtgatga
    33901 tcattatcat tgcgagtttt gcaatcttac tctcttacgc tgactgggat tcacgtgaaa
    33961 aggaagccca gagagtagcc cagcgtgtaa ctgctagaac agtgagtgaa attgaatatt
    34021 accatagaga gtcaacccag atagctcagg ctttagttga aaatcaagct cgtattgagg
    34081 gaatctataa atactttagc cttagcatgc cagactattt ttactggcaa ttagagcgga
    34141 aagcttcgcc ttatatatca gtctctctgt atgaaaatgt tgatgacctc tatgttcgaa
    34201 atgattttgt aactggggtg gccattgctt ttcaagatta caaggaagtc tatgtttcta
    34261 ctaaagacaa acgtagtgga gaaaaaatca gggctgagga tttcaaacca gcaggaaata
    34321 gttttgccat tccggtgtca gatccagtgt cagatcaaga tttaggagtg atttacatct
    34381 ccttggatcc tgctgtttta taccatgcca ttgataatac tagaggtcat actccgatgg
    34441 cagtaacagt gacctcacct tttgatacgg agatttttca tattggtgag acagttgata
    34501 gggagagtga aaattggcta gttggcttaa cttctcatgg atatcaggtt caggtggcag
    34561 ttcctaaaaa ctttgtttta caaggaacag tgactagctc tgctttgatt gtgggtttga
    34621 gccttctctt tattgtcatt ctttatctga ctttgaggca gacttttgct aattaccaaa
    34681 agcaggtagt ggatttagtg gaatccattc aagtcattgc tcaaggcgaa gaggggcgtc
    34741 ggattgacat ttccgaaaaa gatcaggaat tactcctaat cgcggagacg accaatgata
    34801 tgttggatcg attggaaaag aatatccatg atatttacca gttagagctt agtcaaaaag
    34861 atgccaatat gcgagccttg caggcgcaaa tcaatcctca ttttatgtat aatacgctgg
    34921 agttcttgcg catgtatgca gttatgcaga gtcaagatga gttggcagat atcatttatg
    34981 aattcagtag tctcttgcgt aacaatattt ccgacgaaag agagaccctc ctcaaacagg
    35041 aattagaatt ttgccgtaaa tacagctatc tctgcatggt tcgctatccc aagtccattg
    35101 cctatggttt caagatagat ccagagttag agaatatgaa gattcccaag tttaccttgc
    35161 aaccgctggt agaaaactat ttcgcgcatg gtgttgacca caggcggaca gataatgtga
    35221 ttagcatcaa ggctcttaaa caggatggtt ttgtggaaat tttggtggtc gataatggta
    35281 gaggaatgtc ggctgaaaag ttggcaaata tccgagaaaa attaagtcag aaatattttg
    35341 aacaccgagc cagctacagt gatcaaaggc agtctatcgg gattgtcaat gtacacgagc
    35401 gttttgtgct ctattttgga gaccgctatg ccattacgat agagtctgca gagcaagccg
    35461 gtgttcagta tcgtattaca attcaagatg agtagaaagg gagaaaatgt ataaagtatt
    35521 attagtagat gatgagtaca tggtgacaga aggtctgaag cgtttgattc cctttgataa
    35581 gtgggatatg gaggtcgtcg caacagccag tcatgccgat gaagctctag aatatgttca
    35641 ggaaaatcct gtcgatgtca tcatttccga tgtcaatatg ccagacaaaa cagggcttga
    35701 tatgattcgg gagatgaaag agatcttacc agatgctgcc tatatcctgc tctcaggtta
    35761 tcaggagttt gattatgtaa aaagagcaat gaaccttagt gtggtggact atttggtcaa
    35821 gcctgttgat aaggtagagc tgggaaatct gctggagaag attgcaggtc agctcggcga
    35881 gagagggaag aaaagtcaga ctcttagtca agaattagac gaggctggat ttgttagtta
    35941 tttaggggat aaggagaatt ggtggatagg tctatccaag gaaaaacaag gttccttcac
    36001 cattccctac tatgtcttgg gccaagactg gcagattttc atttctgacc aacccctaga
    36061 tggtttagtc gttacacctt ttgaagctcc ttatcaagaa cactttgaac gctggaagct
    36121 gaatgctgag aaaaccctct tttacggttc tgtaaatttg cagcagtctg agagtctctt
    36181 tgcctattac gaaccgattt atagggttat cattcaggga aatctcaatc aaatcgtaga
    36241 agagttaaat ctcttggaga aggtagttct tgaaaatacg ccgcgtgttc cgattactaa
    36301 acagcttttt attcagtttg tcatggatgt tttccattta tttgaacatc tcaaagctga
    36361 tgacctgaca gacatcgtca aaaccattca tgctattcaa tccttcgatg aattggttcc
    36421 ttatatcaag gaaactctga gcagcttttt cggtcaatac cgtatgaatg aaaatgtggt
    36481 cagtgtgctg gaagtcattg gttgtgatta ccaaaaagag ctttccctca aggatatcag
    36541 taaggctctc tttatcaatc ctgtctatct agggcagttg attaagcgtg aaaccgattc
    36601 gacttttgca gagttactaa acaaacaacg tattaaggct gcccaacaac ttttgctttc
    36661 aactagtgac agcatcgaag atatttgtta tgctgttggt tacagtaacc ttggatattt
    36721 ctataaagtt ttccgaaaat tgtgcggaaa atcgccaaaa gcctaccgaa aacaggtaga
    36781 aactatacta taagatttgt attcctttac aaaatgtgct ataatataaa tattattatt
    36841 aggaggttct atcatgaaaa agaaaccaat ttatctatgg gtcttgctaa tcttgtctgc
    36901 ccttatttca gttccgtctc tgtttggaat tgtgagtccc ttgcctagta aagaagccct
    36961 tcgtactgct cagaaacaag ttgcaggggt caatgctcag caattagaag accagcttaa
    37021 ttatacctat agagtagcag aagcatctca ttctattttt aatgttgctt tgattgtgct
    37081 atctactatt ttagtggtcg tagcgattgt cttccttgtt cgtaaaaatt tgcaatatgc
    37141 aaactatact tacgttggct atgttttgtt agctattatt ggttcgattt atggctatgt
    37201 tggtttacaa gacgctgtgc agttggttca agatgagagc atgcgtttga cagtgagtat
    37261 tggttcaaaa gctgttagca ttttctatat cgtcatcaat gttctcttcc tagcccttgt
    37321 cttctataag atgtggcgac aacagaaagc ctcggcagaa gaagaggaaa cagaagagct
    37381 tgcctaagta ttgacaaaaa agaactatca agatacaatc ttggtagttg ttttttgatt
    37441 atagataaaa tcatggaggt acatatgaag ataatttctt tagtttatat tagtttgagt
    37501 ggcaacactg aaagttttgt gacgcgcttg aaagactatc tcttgtccca gtacaaaggg
    37561 attgaggttc aaaagattca tatcaaggat ttagtcaagg aaggcaaaaa tttctatgaa
    37621 atggaccatc cctatgtcgc ttttttgccg acctatctcg aaggtgggaa tggcgtggat
    37681 aacggagatg ttgagatttt gacgacaccg gtgggagatt ttattgccta tggtaacaat
    37741 gctagtaagt gttttggtgt ggttgggtca ggaaatcgta actttaataa ccaatactgc
    37801 ctaacagcca agcaatacag tcaacgcttt ggctttcctg tattggctga ctttgaaatg
    37861 cgaggcatgc tggaagatat caaacatgtc gcagctatta tcgcagattt gtatgagttg
    37921 gaaaaggaga attaatactc aatgaaaatc aaagagcaaa ctaggaagct agtcgcaggt
    37981 tgctcaaagc acagctttga ggttgcagat agagctgacg tggtttgaag agattctcga
    38041 atagtataaa attcttataa gaggtggttg aagttgttca actgtttttt gagtataaac
    38101 agtctttaag aacgtaaaaa agcataagtt caggtcttca aaaccttgtt cttatgcttt
    38161 ttatcataga aatatttgct gaattttctc ttgaaatgaa accttatctt catctcgcgc
    38221 ttgtccctta ccctgctttt ccgattgcga gtgcgtagat aaagaagatg gcgaagccaa
    38281 agaggaaaat caatcccgca atggcaaggt gtttgagcca agaaggaaga tttttgtttt
    38341 cacgcgttac caaggcgtaa ttcaaaagag caaagaaagg tgttgtcagg aaagagccaa
    38401 tcatggcaaa gcggagcatg gttgaaacct gaccagagaa gaacttgata atgacgatac
    38461 cgatgatagc agtgatggtc atccagatgt tcaaagattt acgattgtcc tctttttgac
    38521 tgattagcag tcggagagat tcctgattaa cgcgagaata gccatcgata acagttataa
    38581 ctgttccaaa gatacagagg aaggcaataa aggtaatcaa gtaacgggac cattcgccaa
    38641 gaacagaggc atacatgccc acgaattgag agatgtattt ggctgaagca gcttcaaccg
    38701 cctgccctgt aggatactga atcagtgctc ccagtgccac aaagaagacg gctaggatag
    38761 ctgttccaat ataaccagtg ttaaagtcaa acagagcgtc ttctgtgtta aagttgacgg
    38821 tctttctctt ttcagctgac caaagtgaat tgatggctga aatttcaata ggagccggca
    38881 tccatcctag gagggagacg atgaagggca gagctgccat ttgccaaggt gtcttctcga
    38941 caaaatcaga actgtattct ggatgcttga ccgccgcaat gataactgcc agaacagtcg
    39001 caatggttaa ggcagacata atccatttga ccatgccgtc taaaagtttg tagcctccaa
    39061 agagtagcat agcccaaatg attgcaacga gaatgaggga ccactgagta atgctaagtc
    39121 caatcattgg gaaggcactg gcgatgatag ctgagcacag aatggcaaca ccagccgtgt
    39181 tgaccatagc cgaaaagaca ttgaggataa agaaaatcca gagatagagt tttccttttt
    39241 cggcataacc ttcaaccaaa gtctttccag tatcagctgt gtattcagca ccaaaacgga
    39301 aaaatggata tttaaagaca ttggctaaga tgaccaagag aagtagagac caaccgtaag
    39361 aaccgccagc ttgagttgag gatacaatgt gggaacctcc aacagcggca gttgccatta
    39421 ggattccagg tcccattgct tttagcttgc ttgcccaggt tgattgattt aaggaaatag
    39481 cttgcgacat gataaatact cctttttgaa ttttcagaat aatctgtata tgtaatctat
    39541 attctacaaa aaattttgga aaaatgcaag aatattttga aaaaagatag aaaatttaca
    39601 aagaaaat
//
LOCUS       DAVAZV010000014        37667 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVAZV010000014 DAVAZV010000000
VERSION     DAVAZV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.014"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            108..896
                     /gene="codY"
                     /locus_tag="VQT46_000707"
     CDS             108..896
                     /gene="codY"
                     /locus_tag="VQT46_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET2370766.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            896..1471
                     /locus_tag="VQT46_000708"
     CDS             896..1471
                     /locus_tag="VQT46_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET2370767.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDFFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            1553..1638
                     /locus_tag="VQT46_000709"
     tRNA            1553..1638
                     /locus_tag="VQT46_000709"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1587..1589,aa:Leu,seq:aag)
     gene            1921..3051
                     /gene="ugpC"
                     /locus_tag="VQT46_000710"
     CDS             1921..3051
                     /gene="ugpC"
                     /locus_tag="VQT46_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET2370768.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(3198..3344)
                     /locus_tag="VQT46_000711"
     CDS             complement(3198..3344)
                     /locus_tag="VQT46_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370769.1"
                     /translation="MEIKEQTRKLAVSCSKYIFEVADKTDEISNHTYGKATLTWFEEI
                     FEEY"
     gene            3552..4310
                     /locus_tag="VQT46_000712"
     CDS             3552..4310
                     /locus_tag="VQT46_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET2370770.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGLSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKVLTGEMTLMKLSGMIYDEGWLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            4397..4909
                     /locus_tag="VQT46_000713"
     CDS             4397..4909
                     /locus_tag="VQT46_000713"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET2370771.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            5091..6035
                     /locus_tag="VQT46_000714"
     CDS             5091..6035
                     /locus_tag="VQT46_000714"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET2370772.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            6044..6721
                     /locus_tag="VQT46_000715"
     CDS             6044..6721
                     /locus_tag="VQT46_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET2370773.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            6819..7577
                     /locus_tag="VQT46_000716"
     CDS             6819..7577
                     /locus_tag="VQT46_000716"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET2370774.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            7615..9120
                     /gene="lytC"
                     /locus_tag="VQT46_000717"
     CDS             7615..9120
                     /gene="lytC"
                     /locus_tag="VQT46_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET2370775.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAESDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTGTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPHYSGKKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            9616..10134
                     /locus_tag="VQT46_000718"
     CDS             9616..10134
                     /locus_tag="VQT46_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET2370776.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            10264..10770
                     /locus_tag="VQT46_000719"
     CDS             10264..10770
                     /locus_tag="VQT46_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET2370777.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            10770..10940
                     /locus_tag="VQT46_000720"
     CDS             10770..10940
                     /locus_tag="VQT46_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370778.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            10972..12204
                     /gene="clpX"
                     /locus_tag="VQT46_000721"
     CDS             10972..12204
                     /gene="clpX"
                     /locus_tag="VQT46_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET2370779.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            12213..12800
                     /locus_tag="VQT46_000722"
     CDS             12213..12800
                     /locus_tag="VQT46_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET2370780.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            12811..13191
                     /locus_tag="VQT46_000723"
     CDS             12811..13191
                     /locus_tag="VQT46_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET2370781.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            13243..14133
                     /gene="rapZ"
                     /locus_tag="VQT46_000724"
     CDS             13243..14133
                     /gene="rapZ"
                     /locus_tag="VQT46_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET2370782.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            14130..15107
                     /locus_tag="VQT46_000725"
     CDS             14130..15107
                     /locus_tag="VQT46_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET2370783.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            15104..16015
                     /gene="whiA"
                     /locus_tag="VQT46_000726"
     CDS             15104..16015
                     /gene="whiA"
                     /locus_tag="VQT46_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET2370784.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLVNGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(16049..17017)
                     /locus_tag="VQT46_000727"
     CDS             complement(16049..17017)
                     /locus_tag="VQT46_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2370785.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWTLAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            17153..18010
                     /locus_tag="VQT46_000728"
     CDS             17153..18010
                     /locus_tag="VQT46_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET2370786.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            17997..18776
                     /locus_tag="VQT46_000729"
     CDS             17997..18776
                     /locus_tag="VQT46_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET2370787.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            18800..20152
                     /locus_tag="VQT46_000730"
     CDS             18800..20152
                     /locus_tag="VQT46_000730"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET2370788.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAIQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            20226..20600
                     /locus_tag="VQT46_000731"
     CDS             20226..20600
                     /locus_tag="VQT46_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET2370789.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            20602..21450
                     /locus_tag="VQT46_000732"
     CDS             20602..21450
                     /locus_tag="VQT46_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2370790.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            21727..22494
                     /locus_tag="VQT46_000733"
     CDS             21727..22494
                     /locus_tag="VQT46_000733"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET2370791.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDDMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            22506..23690
                     /locus_tag="VQT46_000734"
     CDS             22506..23690
                     /locus_tag="VQT46_000734"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET2370792.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGDILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            23687..25558
                     /locus_tag="VQT46_000735"
     CDS             23687..25558
                     /locus_tag="VQT46_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2370793.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDSKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQT46_000736"
     CDS             complement(25701..26885)
                     /gene="mntE"
                     /locus_tag="VQT46_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET2370794.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPISEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            27189..29885
                     /locus_tag="VQT46_000737"
     CDS             27189..29885
                     /locus_tag="VQT46_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET2370795.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            29898..30689
                     /gene="yghU"
                     /locus_tag="VQT46_000738"
     CDS             29898..30689
                     /gene="yghU"
                     /locus_tag="VQT46_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET2370796.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            30805..31215
                     /locus_tag="VQT46_000739"
     CDS             30805..31215
                     /locus_tag="VQT46_000739"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2370797.1"
                     /translation="MEKKIVKDILFLSQVSHPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGMQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            31227..32822
                     /locus_tag="VQT46_000740"
     CDS             31227..32822
                     /locus_tag="VQT46_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370798.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKVQ"
     gene            32989..33153
                     /locus_tag="VQT46_000741"
     CDS             32989..33153
                     /locus_tag="VQT46_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET2370799.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            33232..33960
                     /gene="yaaA"
                     /locus_tag="VQT46_000742"
     CDS             33232..33960
                     /gene="yaaA"
                     /locus_tag="VQT46_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET2370800.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(34011..35495)
                     /locus_tag="VQT46_000743"
     CDS             complement(34011..35495)
                     /locus_tag="VQT46_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2370801.1"
                     /translation="MRNLLSTKVQRQLRLMETLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEGYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYISGITKKFICRNHLSIMNLVNHLNTLSNEIHLSNTL"
     gene            35711..>37667
                     /locus_tag="VQT46_000744"
     CDS             35711..>37667
                     /locus_tag="VQT46_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET2370802.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKPAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDVDR
                     GYSGFRAAPAPTNQPVTNLGNNTVFTDISRGSHTFRGNGNSRRGNPIHFDVTTTRVRN
                     RVDFSIRYSGPGEFVNNNFILDKGNGFGEPSRATVSTPKLRDQVKNISKGGNFVSHSG
                     YSLEAAVETSTNQTIKFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGDRGERGLTGAQGAKGEKGDRGERGLTG
                     AQGAKGEKGDRGERGLTGAQGAKGEKGD"
BASE COUNT        11317 a         6899 c         8566 g        10885 t
ORIGIN      
        1 tttaattaaa ttgtaagtca atgcaagtca ataaggaatt ttcagataat tattgaaaaa
       61 gagacgtttt tatgttataa tgatagcgat taaattcgag gtgaaaaatg gcacatttat
      121 tagaaaaaac tagaaaaatt acatcaattt tgaaacgctc agaggagcag ttgcaggatg
      181 agctccctta caacgctatt acgcgtcagt tagcggatat tattcattgc aatgcctgca
      241 ttatcaatag taagggacgt ctgcttggct attttatgcg ttataaaaca aatacagatc
      301 gcgtagagca attcttccaa actaagattt tcccagatga ctacgttcaa ggggctaata
      361 tgatttacga aacagaagca aacttgcctg ttgagcatga tatgagtatt ttccctgttg
      421 agagtagaga tgattttcca gatggcttga cgactattgc accgattcat gtatcgggga
      481 ttcgccttgg ttctttgatt atttggcgta atgataaaaa attcgaagat gaggacttgg
      541 ttcttgttga gattgccagt accgttgttg ggattcagct tcttaacttc caacgtgaag
      601 aagatgagaa aaatattcgt cgtcgtactg ctgtcaccat ggcggtcaat accctttctt
      661 actccgaact ccgtgctgtt tcagcaattt taggggaatt aaatggaaat gaagggaagt
      721 tgactgcgtc agtgattgca gatcgtatcg gaatcactcg ctctgtgatt gtcaatgctc
      781 ttcgtaaact tgagtctgcg gggattattg aaagtcgctc acttggaatg aagggaacct
      841 atcttaaggt cttgatttca gatatttttg aagaagtgaa gaaaagagat tactaatgac
      901 aaaggcttta atttcgattg attatacaga agattttgtt gctgatagtg ggaagctgac
      961 agcaggtgct ccagctcagg cgatttcgga tgccatcagc aaggtaactc gattagcttt
     1021 tgaacgagga gattatatct tctttactat tgatgctcat gaagaaaacg attttttcca
     1081 tccggaaagt aagttatttc ctcctcataa tctgattggg acgagtggac ggaatttata
     1141 tggagatttg gggatctttt atcaagagca tggttcagac agtcgtgtct tttggatgga
     1201 taaacgccat tactcagctt tttcagggac tgacctagat attcgtttga gagagcgtag
     1261 agtgtctacc gttatcttaa caggtgtctt gacggatatc tgtgtcctac atacagctat
     1321 agatgcctat aatctaggat atgacatcga gattgttaaa ccagctgttg cttccatctg
     1381 gcctgaaaat catcaatttg ccctaggtca tttcaaaaat acactcggag ctaagttagt
     1441 agatgaaaat ctaaatgaac tttctgagta acctggttgg tgaaaatgaa aaaatttgaa
     1501 aaaaagtgtt gacaagcatc ccaaaagttg atatactagt aaagtaatcg atgcggggat
     1561 ggcggaattg gcagacgcgc aggactaagg atcctgtgac cgctttaggt cgtgagggtt
     1621 caagtccctc tctccgcata ggaaaagagt tagctaaagc tagctctttt gtatttctct
     1681 aaaaaattag aatccagtca aatgtagtgg agaatcagcg aaaatatggg aaaactgttc
     1741 cttgtttctg cttttgtcat agaagaataa taaagattat cttcttcaaa ttctccgata
     1801 ttctctaaag ttttgtgcaa gttgcacaga acttttttat ttttttggtc atcttgccat
     1861 agaaatataa agcgttttca tctataatat aattatcaaa agacaaaagg agttcacctc
     1921 atggtagaat tgaatcttaa aaatatttac aaaaaatatc caaacagcga acactattca
     1981 gttgaagatt tcaacttgaa catcaaagat aaagaattta tcgttttcgt aggaccttca
     2041 ggatgtggta aatcaactac actccgtatg attgctggtc ttgaagacat tacagaaggt
     2101 actgcatcta tcgatggcgt ggttgtcaac gacgtagctc caaaagaccg tgatatcgcc
     2161 atggtattcc aaaactacgc tctttaccca cacatgactg tttatgacaa catggctttc
     2221 ggtttgaaat tgcgtaaata cagcaaagaa gacattaaca aacgtgttca agaagcagct
     2281 gaaatacttg gattgaaaga attcttggaa cgtaaaccag ctgacctttc aggtggtcaa
     2341 cgtcaacgtg ttgccatggg gcgtgcgatt gtccgtgatg cgaaagtatt cttgatggac
     2401 gaacctttgt caaacttgga tgccaaactt cgtgtatcaa tgcgtgctga aatcgctaaa
     2461 attcaccgtc gtatcggagc tacaactatc tatgtaactc acgaccaaac agaagcgatg
     2521 acacttgcag accgtatcgt tattatgtca gctactaaga accctgctgg tacaggtact
     2581 atcggacgtg tagaacaaat cggtactcct caagaagttt acaaaaatcc agttaacaaa
     2641 ttcgttgcag gattcatcgg aagcccagct atgaacttca tcaacgtgaa attggttggt
     2701 agcgaaattg tttctgacgg tttccgtttg aaagtgccag aaggagcatt gaaagttctt
     2761 cgtgaaaaag gctacgaagg aaaagaattg atctttggta tccgtccaga agacgtgaat
     2821 gcagaacctg ctttccttga aacattccca gactgtgttg taaaagcgac tatctctgta
     2881 tcagaactgc ttggttcaga atctcacctt tactgccaag ttggtaaaga cgagtttgtt
     2941 gcaaaagttg atgctcgtga ctacttgcaa acaggtgcaa cagttgagct tggatttgac
     3001 ttgaacaaag cacacttctt cgatgtagaa actgaaaaaa caatctacta aaataaataa
     3061 aattcaaagc actacaagaa aagatatctc tttatcaatt gtagtggaga gatatcagtt
     3121 aatctaggga gagaaacaaa atgcttctct cctttttgct agggaagtca tattatgcat
     3181 ctatattgtg atgctcttta atactcttcg aaaatctctt caaaccacgt caacgtcgcc
     3241 ttgccgtacg tatgattact gatttcgtca gttttatctg caacctcaaa gatgtacttt
     3301 gagcagctta cggctagttt cctagtttgc tctttgattt ccattgagta ttatttgtgg
     3361 gtaccatcta caagtgaagc tatatgcgta aactacgtga gcaattgaat tcgaactaga
     3421 gaggtaataa taaatttatg ctatagttat ggtgacttgt atgcttttga ttctagttta
     3481 tcaaataata gattagaatt gtcagataat atcattttgt gttataatga agaaaaaaca
     3541 gaggtgttca aatgtcagaa gcaggtcata agtttttagc aaaattgggg aaaaaacgct
     3601 tacgtccagg tggaaagcgt gctacagatt ggttaattgc agaaggagga ttgtcaaaag
     3661 aaaagagaat actagaggtt gcgtgtaata ggggaactac agcaattgag ttggcacagc
     3721 gttttggttg caagataact gctgttgata tggatgctca agctttagaa gtggctaaaa
     3781 aatctgctgg aacggcaggt gttgctcatt taatcagttt tgaaagagca aatgcaatga
     3841 aacttcctta tcaagatgct agttttgata ttgttataaa tgaagctatg ctgactatgc
     3901 aagccgatca agctaagaaa aaatgtgtaa tggaatatct aagggtatta aaacctggag
     3961 gtcttctttt gacacatgat gtgcttctta aggaagctaa agagtctatc agacaggaat
     4021 tatcacaagc aattcatgta aatgtaggtc ctttaactca agatggttgg gaacaggtga
     4081 tgatagaatc aggttattgt gatgtgaaag tattgactgg tgaaatgaca ttaatgaaat
     4141 tatcgggtat gatttatgac gaaggttggc taggaacttt gaaaatttgt gtaaatgctt
     4201 gtaaaaagga gaatagaaag cagtttttaa ctatgtataa aatgtttgct aagaataaac
     4261 agaaattggg ctttattgcg atggctagtt ataaatcgtc aaaacgttag ataattattg
     4321 aagttaactt ttcctttttt ctttcttaaa aaatatgcta taatagagag tgaaaaactt
     4381 tgaaagaaag aaaaagatga atttaaaaga ttacattgca acaattgaaa attatccaaa
     4441 ggaaggcatt accttccgtg atattagtcc tttgatggct gatggaaatg cttatagcta
     4501 cgctgttcgt gaaatcgttc agtatgctac tgacaagaaa gtcgacatga tcgtgggacc
     4561 tgaagctcgt ggatttatcg tgggttgtcc agttgccttt gagttgggaa ttggttttgc
     4621 gcctgttcgt aagccaggta aattgccacg cgaagttatt tctgctgact atgaaaaaga
     4681 gtacggtgtc gataccttga ctatgcacgc ggatgccatt aagccaggtc aacgtgttct
     4741 tattgtagat gaccttttgg cgacaggtgg aactgttaag gcaactatcg agatgattga
     4801 aaaacttggt ggtgttatgg caggttgtgc cttccttgtt gaattggatg aattgaacgg
     4861 ccgtgaaaaa atcggtgact acgactacaa agttcttatg cattattaat gaaaacagtc
     4921 cctagggctg ttttctctac actaggatat aaaaatagac tataactagt tagagaaaaa
     4981 ctataattga aaactatatc ttcttgcagt ataataaaag gactaagtgt ttgagatttg
     5041 tcttcaaaca catgcaatta ttcctgagag agtacagtta ggagagggtt atgccgattc
     5101 gaattgataa aaaattgcca gctgttgaga ttttacggac agagaatatc tttgtcatgg
     5161 atgatcaacg tgctgcccac caagatatcc gtcctttgaa gattttaatt ttaaatctca
     5221 tgccacagaa aatggtcaca gagacccagt tgttgcgtca cttggctaat acacccctac
     5281 aactggatat tgattttctc tatatggaga gccaccgttc taaaacaact cgttcagagc
     5341 acatggagac cttctataaa acttttcctg aagtcaagga tgagtatttt gatgggatga
     5401 tcatcacggg tgctccagtt gagcatttac catttgagga agtggactat tgggaggaat
     5461 ttaggcagat gcttgagtgg tctaagacac atgtctattc gacccttcat atctgttggg
     5521 gggctcaggc tgggctttat ctgcgctatg gtgtagaaaa ataccagatg gacagtaagc
     5581 tatcaggtat ttatcctcag gacaccctaa aagagggtca ccttctattt agaggctttg
     5641 atgatagcta tgtatcccct cattcacggc acacggagat ttctaaggaa gaggtcttaa
     5701 acaagaccaa tctcgagatt ttatcagaag gacctcaggt tggggtttct attttggcca
     5761 gtcgtgattt acgagaaatt tatagttttg gtcatttgga gtatgaccgt gataccttgg
     5821 caaaagagta ttttcgagat cgtgatgcag gtttcgaccc acatattcca gaaaattact
     5881 ttaaagatga tgatgttaat caggtacctt gtctttgttg gtcttcatct gcagccctct
     5941 ttttcagtaa ttgggtaaac catgcggtct atcaggagac gccttttgat tggagaaaga
     6001 tagaagatga tgcatctgca tatgggtatt tataagagga attatgacat atttagacgc
     6061 ttttaaatca ggtaccttgg ttttaccgag tgccctgctc ttgcatttta aggaactctt
     6121 tccttctagc gacgattttc tggtttggca atttttctat ttgcaaaata cgacaggctt
     6181 agaagaaatg tcgccaagcc agattgctga aaggattggc aaggaaattt cggatgtcaa
     6241 ccagtccatt tctaatctga cggaaagggg actgctccag tatcgtacta tcgaattaaa
     6301 tggcgaaatt gaattgctct ttgatgctag tttggccttg gaacgtttgg atgacctgtt
     6361 tggagcagtt cgttcaagtt cagaccagct aacacctcaa aaccagctca aggatttggt
     6421 ggaaaccttc cagcaggagt tgggacgatt gttgacgcct tttgagattg aggatttgac
     6481 caagacacta aaggaagatg gaaccagtgc tgacttgatt aaggaggctc ttcgtgaagc
     6541 tgttttgaat ggaaaaccaa actggaagta cattcaggcg attttgagaa actggcgcca
     6601 tgaaggaatc aagagtgtgg ctcaaattga ggccaagaga gcagaaagag aagcaagcaa
     6661 tcctcagttg acacaggtat ctgcagattt cagaaatgcc atggatctct ggaaggatta
     6721 atccatgcaa gtaggcttga aatccgagta agatttgcaa gctgtgtata attgtgatag
     6781 aataaataga aaataaattg aaaaaagagg tatgtgaaat gtcacgtaaa ccatttatcg
     6841 ctggtaactg gaaaatgaac aaaaatccag aagaagctaa agcattcgtt gaagcagttg
     6901 catcaaaact tccttcatca gatcttgttg aagcaggtat cgctgctcca gctcttgatt
     6961 tgacaactgt tcttgctgtt gcaaaaggct caaaccttaa agttgctgct caaaactgct
     7021 actttgaaaa tgcaggtgct ttcactggtg aaactagccc acaagttttg aaagaaatcg
     7081 gtactgatta cgttgttatc ggtcactcag aacgccgtga ctacttccat gaaactgacg
     7141 aagatatcaa caaaaaagca aaagcaatct ttgcgaacgg tatgcttcca atcatctgtt
     7201 gtggtgaatc acttgaaact tacgaagctg gtaaagctgc tgaattcgta ggtgctcaag
     7261 tatctgctgc attggctgga ttgactgctg aacaagttgc tgcctcagtt atcgcttatg
     7321 agccaatctg ggctatcggt actggtaaat cagcttcaca agacgatgca caaaaaatgt
     7381 gtaaagttgt tcgtgacgtt gtagctgctg actttggtca agaagtcgca gacaaagttc
     7441 gtgttcaata cggtggttct gttaaacctg aaaatgttgc ttcatacatg gcttgcccag
     7501 acgttgacgg tgcccttgta ggtggtgcgt cacttgaagc tgaaagcttc ttggctttgc
     7561 ttgactttgt aaaataatca gtaagtagca aaagctaggt ggaacagcat tcagatgtct
     7621 gttacatttt ttataggaga ggaaagattg aaaacaaaaa ttggattagc aagtatctgt
     7681 ttactaggct tggcaactag tcatgtcgct gcaaatgaaa ctgaagtagc aaaaacttcg
     7741 caggatacaa cgacagcttc aagtagttca gagcaaaatc agtcttctaa taaaacgcaa
     7801 acgagcacag aagtacagac taatgctgct gcccactggg atggggatta ttatgtaaag
     7861 gatgatggct ctaaagctca aagtgaatgg atttttgaca actactataa ggcctggttt
     7921 tatattaatt cagatggtcg ttactcgcag aatgaatggc atggaaatta ctacctgaaa
     7981 tcaggtggat atatggccca aaacgagtgg atctatgaca gtaattacaa gagttggttt
     8041 tatctcaagt cagatggggc ttatgctcat caagaatggc aattgattgg aaataagtgg
     8101 tactacttca agaagtgggg ttacatggct aaaagccaat ggcaaggaag ttatttcttg
     8161 aatggtcaag gagctatgat gcaaaatgaa tggctctatg atccagccta ttctgcttat
     8221 ttttatctaa aatccgatgg aacttatgct aaccaagagt ggcaaaaagt gggcggaaaa
     8281 tggtactatt tcaagaagtg gggctatatg gctcggaatg agtggcaagg caactactat
     8341 ttgactggaa gtggtgctat ggcgactgac gaagtgatta tggatggtgc tcgctatatc
     8401 tttgcggcct ctggtgagct caaagaaaag aaagatttga atgtcggctg ggttcacaga
     8461 gatggtaaac gctatttctt taataataga gaagaacaag tgggaaccga acatgctaag
     8521 aaaatcattg atattagtga gcacaatggt cgtatcaatg attggaaaaa ggttattgat
     8581 gagaacgagg tggatggtgt cattgttcgt ctaggttata gcggtaaaga agacaaggaa
     8641 ttggcgcata acattaagga gttaaaccgt ctgggaattc cttatggtgt ctatctctat
     8701 acctatgctg aaaatgagac cgatgctgag agtgacgcta aacagaccat tgaacttata
     8761 aagaaataca atatgaacct gtcttaccct atctattatg atgttgagaa ttgggaatat
     8821 gtaaataaga gcaagagagc tccaagtgat acaggcactt gggttaaaat catcaacaag
     8881 tacatggaca cgatgaagca ggcgggttat caaaatgtgt atgtctatag ctatcgtagt
     8941 ttattacaga cgcgtttaaa acacccagat attttaaaac atgtaaactg ggtagcggcc
     9001 tatacgaatg ctttagaatg ggaaaaccct cattattcag gaaaaaaagg ttggcaatat
     9061 acctcttctg aatacatgaa aggaatccaa gggcgcgtag atgtcagcgt ttggtattaa
     9121 gcgatgattt gaaagaggga tgtgatagta gcaccctctt tttctttgtt ttatgatagt
     9181 tcatcctcga gtaaattcaa gttcttgctc ggaaatgaag cttatatagt agattgaata
     9241 tagacaaata ccttgtgatt ggtaaaacat tttagaaatt catttacctt tcctaatcga
     9301 cttggtttca tcttatttca atctattata gtattgggga atttcttcaa accacatcag
     9361 cttggtcagt tctacctgcg acctcaaaac ttgtgctttg gtcaagctgg gtttagtttc
     9421 ctagtttgct gatggatttc cattgactat aagcatccaa ccctcttttt gtcttctaaa
     9481 gaattcttaa attatcagtc tattgcaact tttctcatat aagttctttg tcttgctatt
     9541 ggttttcctt agtagtatac taaggtagta atcattaaga agtggttaca aaaaataatg
     9601 aatgaggtaa agaaaatggt agaattgaaa aaagaagcag taaaagacgt aacatcattg
     9661 acaaaagcag cgccagtagc attggcaaaa acaaaggaag tcttgaacca agctgttgct
     9721 gatttgtatg tagctcacgt tgctttgcac caagtgcact ggtatatgca tggtcgtggt
     9781 ttccttgtat ggcatccaaa aatggatgag tacatggaag ctcttgacgg tcaattggat
     9841 gaaatcagtg aacgcttgat tacactcggt ggaagcccat tctctacatt gacagagttc
     9901 cttcaaaata gtgaaatcga agaagaagct ggtgaatacc gtaatgttga agaaagcttg
     9961 gaacgtgttc ttgttatcta ccgttacttg tcagaacttt tccaaaaagg tttggatgtc
    10021 actgatgaag aaggtgacga tgtgacaaac ggtatctttg caggcgctaa aactgaaaca
    10081 gataaaacaa tttggatgct tgcagccgaa cttggacaag cacctggttt gtaagaaata
    10141 aggaaacata gataaatctg taggaaattt cttacagatt ttttctattt tgtaagctat
    10201 tccaaaccag tctttttttg agttttttga taaaatagta ctatcagtga aaaggatgga
    10261 agcatgacta agaaaatcgt agctatttgg gcccaggatg aagagggtgt gattggtaag
    10321 gaaaatcgtc tgccttggca tttgccagca gaattgcagc actttaaaga aacaactctg
    10381 aatcatgcta tcttgatggg gcgtgtgacc tttgatggga tggggcgtcg cttgcttcca
    10441 aaacgggaaa ccttgatttt gacgcgtaat ccggaagaaa agatagatgg ggttgctact
    10501 tttcaggacg tccagtctgt tcttgactgg tatcaggctc aagaaaagaa tctctacatt
    10561 atcggtggga agcaaatttt tcaggctttt gaaccttacc ttgatgaagt gattgtcact
    10621 cacattcatg ctcgggtgga aggagatacc tatttccctg aagaacttga cttgtctctt
    10681 tttgagacag tttcaagcaa attttacgcc aaagatgaga agaatcctta tgattttacc
    10741 atccaatacc gcaagagaaa ggaagtctaa tggaacggag tttatttggt ctattcacgg
    10801 cttttctgtg tttcatctgc tttctggcag gagcacaagc ttttcgtaaa aagcgttacg
    10861 ggctttctat cctcctttgg ttaaatgcct ttaccaatct ggtcaatagt attcatgctt
    10921 tttacatgac cttattttag atagaatgac agtatagaat ggaaggaaat catgtctaca
    10981 aatagaaaaa atgatatgat ggtttattgc tcattttgtg gcaaaaacca agaagaagta
    11041 caaaaaataa ttgctggcaa caatgctttt atttgtaatg aatgcgtgga gttagctcag
    11101 gaaatcattc gagaagaatt ggttgaggaa gtcttggcag acttgtctga ggtgccaaaa
    11161 ccaattgaac tcctccatat cttgaaccac tatgtaattg gtcaagatcg tgccaagcgt
    11221 gccttggcag tggcggttta taaccactac aaacgcatca atttccacga tacacgcgaa
    11281 gagtcagaag atgtggattt gcagaagtca aacattttga tgattggccc aactggttca
    11341 gggaaaactt tccttgccca gaccttggct aagagcttga atgtaccttt tgctattgcg
    11401 gatgcgacag ctctgacgga ggctggttat gtgggtgagg atgtggaaaa tatactcctc
    11461 aaactcttgc aggttgctga ctttaacatc gaacgtgcag agcgtggcat tatctatgtg
    11521 gatgaaattg acaagattgc caagaagagt gagaatgtgt ctatcacacg tgatgtttct
    11581 ggtgaagggg tgcaacaagc ccttctcaag attattgagg gaactgttgc tagcgtaccg
    11641 cctcaaggtg gacgcaaaca tccacaacaa gagatgattc aagtggatac aaaaaatatc
    11701 ctcttcatcg tgggtggtgc ttttgatggt attgaagaaa ttgtcaaaca acgtctgggt
    11761 gaaaaagtca tcggatttgg tcaaaacaat aaggcgattg acgaaaacag ctcatacatg
    11821 caagaaatca tcgctgaaga cattcaaaaa tttggtatta tccctgagtt gattggacgc
    11881 ttgcctgttt ttgcggctct tgagcaattg accgttgatg acttggttcg catcttgaaa
    11941 gagccaagaa atgccttggt gaaacaatac caaaccttgc tttcttatga tgatgttgag
    12001 ttggaatttg acgacgaagc ccttcaagag attgctaata aagcaatcga acggaagaca
    12061 ggggcgcgtg gacttcgctc catcatcgaa gaaaccatgc tagatgttat gtttgaggtg
    12121 ccgagtcagg aaaatgtgaa attggttcgt atcactaaag aaactgtcga tggaacggat
    12181 aaaccgatcc tagaaacagc ctagaggtga ctatggaact taatacacac aatgctgaaa
    12241 tcttgctcag tgcagctaat aagtcccact atccgcagga tgaactgcca gagattgccc
    12301 tagcagggcg ttcaaatgtt ggtaaatcca gctttatcaa cactatgttg aaccgtaaga
    12361 atctcgcccg tacatcagga aaacctggta aaacccagct cctgaacttt tttaacattg
    12421 atgacaagat gcgctttgtg gatgtgcctg gttatggcta tgctcgtgtt tctaaaaagg
    12481 aacgtgaaaa gtgggggtgc atgattgagg agtacttaac gactcgggaa aatctccgtg
    12541 cggttgtcag tctagttgac cttcgtcatg acccgtcagc agatgatgtg cagatgtacg
    12601 aatttctcaa gtattatgag attccagtca tcattgtggc gaccaaggcg gacaagattc
    12661 ctcgtggtaa atggaacaag catgaatcag caatcaaaaa gaaattaaac tttgacccaa
    12721 gtgacgattt catcctcttt tcatctgtca gcaaggcagg gatggatgag gcttgggatg
    12781 caatcttaga aaaattgtga ggaaaagaaa atggcaaaaa caattcatac agataaggcc
    12841 ccaaaggcta tcggacccta tgttcaagga aaaatcgttg gcaacctttt gtttgctagc
    12901 ggtcaagttc ccctatcccc tgaaactggg gaaattgtag gagagaatat ccaagaacag
    12961 acagagcaag tcttgaaaaa catcggtgct attttggcag aagcaggaac agactttgac
    13021 catgttgtca aaacaacttg cttcttgagc gatatgaacg actttgttcc ttttaatgag
    13081 gtttaccaaa cggccttcaa agaggaattc ccagctcgtt cagctgtgga ggtagctcgt
    13141 cttcctcgtg atgtaaaagt cgaaattgaa gtcatcgcag agattggata agctagttga
    13201 agtttggtgt tgccaaactt cttttgatat aaggagaaaa agatgacaaa gaaacaactt
    13261 cacttggtga ttgtgacagg gatgagtggc gcagggaaaa ctgtagccat tcagtccttc
    13321 gaggatctag gttatttcac cattgataat atgccgccag ctctcttgcc taagtttttg
    13381 cagctggttg aaattaagga agataatcct aagttggctt tggtagtgga tatgcgtagc
    13441 cgttctttct tttcagagat tcaagctgtt ttggatgagt tggaaaatca agatggtttg
    13501 gatttcaaaa tcctcttttt ggatgcggct gataaggaat tggtcgctcg ttacaaggaa
    13561 accagacgga gtcacccact agcagcagac ggtcgtattt tagatggaat caagttggaa
    13621 cgtgaactct tggcaccttt gaaaaatatg agccaaaatg tggtggatac gactgaactc
    13681 actccacgtg aactgcgcaa aacccttgca gagcagtttt cagaccaaga acaagcccag
    13741 tctttccgta tcgaagtcat gtctttcgga tttaagtatg gaatcccgat tgatgcggac
    13801 ttggtctttg atgtccgttt cttgccaaat ccctattatc taccagaact gagaaaccaa
    13861 acgggtgtgg atgaacctgt ttatgattat gtcatgaacc atcctgagtc agaagacttt
    13921 tatcaacatt tattggcctt gattgagccg attctgccaa gttaccaaaa ggaaggtaag
    13981 tccgttttga ccattgctat gggatgtacg ggtggacaac accgtagtgt ggcatttgct
    14041 aaacgcttgg cgcaggactt atccaagaat tggtctgtta atgaagggca tcgcgacaaa
    14101 gaccgcagaa aggaaacggt aaaccgttca tgagaaaacc aaagataacg gtgattggtg
    14161 gagggactgg aattcccgtc attctaaaaa gtctgcggga aaaagatgtg gaaatcgcag
    14221 ctatcgtgac ggtggcagat gatggtggtt cttcaggtga actccgaaaa aatatgcaac
    14281 agttgacacc gccaggtgat cttcgtaatg tccttgtggc catgtcggat atgcctaagt
    14341 tttatgagaa ggtctttcag tatcggttct ctgaggatgc cggagccttt gctggccatc
    14401 cattgggaaa tctcatcatt gctggcttgt cagaaatgca gggttcaacc tataatgcca
    14461 tgcagttatt gagcaaattt ttccatacaa cagggaaaat ttatccttcc agtgaccatc
    14521 ctttgaccct tcatgcagtc tttcaggatg ggacagaagt ggctggagag agtcatattg
    14581 tagaccatcg aggcataatt gacaatgtct atgtgaccaa tgccctaaac gatgatacgc
    14641 ctctggccag ccgtcgagta gtgcagacca tccttgaaag tgacatgatt gtcctagggc
    14701 caggttccct ctttacctct attttgccca atatcgtgat taaggaaatt gggcgggctc
    14761 ttttggaaac taaggcagaa attgcctatg tctgcaatat catgacccaa cgtggggaga
    14821 cggaacactt tacagatagc gaccacgtgg aagtcttgca tcgtcacctt ggtcgccctt
    14881 ttatcgacac tgtcttggtg aatattgaaa aagtgcctca ggaatacatg aattccaacc
    14941 gttttgatga atacttggtg caagtggaac acgattttgt aggtctttgt aagcaagttt
    15001 cgcgcgtgat ttcatctaac ttccttcgtc tggaaaatgg cggtgccttc cacgatggag
    15061 atttgattgt ggacgagttg atgcgcatta tacaggtgaa aaaatgagtt tcacagtagc
    15121 agtaaaagaa gaaatcctgg gccaacacca tctgagccgg catgaattat ctgccattat
    15181 caaaatgtct ggtagcatcg gtctctcgac ttcgggcttg actttgtcag ttgtgacaga
    15241 aaatgccaaa ctggcccgtc acctctatga gtcctttctc catttctatg aaatcaaatc
    15301 tgaaattcgt caccaccaac ggagcaatct tcgcaagaat cgcgtctata ccgtttttac
    15361 agatgaaaag gtgcaggatt tgttaagtga tttgcacttg gcagactctt tctttggcct
    15421 ggaaacaggt attgatgagg cgattttatc ggatgaggaa gcaggtcgtg cctatctctg
    15481 tggcgctttc ttggtaaatg ggagcattcg tgaccctgag tcaggcaagt accagttgga
    15541 aatcagttct gtttatctgg accacgcgca aggaattgcc tcccttctcc aacagttttt
    15601 actggatgcc aaggtgcttg agcgcaagaa gggggctgtg acctatctcc agcgagcaga
    15661 agacattatg gacttcttga tagtaatcgg agccatgcag gcacgtgatg attttgagcg
    15721 ggttaagatt ttgcgagaaa cccgtaacga cctcaatcgg gctaataatg ccgagacagc
    15781 taatatcgct cggacagttt ctgccagcat gaagaccatt aacaatatca gtaaaataaa
    15841 agatatcatg ggcttagaaa atttgccagt agatttgcag gaagtggcgc aactgaggat
    15901 tcagcaccca gactactcta tccagcagtt agcagatagt ctcagcaccc ctctgaccaa
    15961 aagtggtgtc aatcacagac tcagaaaaat caataagata gcggatgaat tataaaacca
    16021 cgaatcctat gtgactcgtg gttctttttt ataaactggt agagtgtttt ggttgtactt
    16081 tttgttcagg gtcaatgtag ttgatagcgt tgttgacagc agttggagct tctccgaggc
    16141 ctgtcgcaat cagatcaatt tttccgtcat agtagcagca gtcaccgata gcatagatac
    16201 ctgcttggct ggattcctgt ttgctgttga cgataatctt gtgacggttg aggtcgagcc
    16261 cccagttttt aaggttaccg acagaagatt tgaaaccata gttgacaaag aggtggtcta
    16321 ggtcaatggt ttcagtttca tcagatttga cttttgtgat ttcaagttta tcaagtgttt
    16381 ttccatttcc aaggagttgg ctaggggcga atggtgtctt gatggttaca gatgattctt
    16441 gcaaggcttg aacactgtgt tccaaggcac ggaaattatc tctgcggtga acaagggtag
    16501 ttggtgcgat tttttcaaaa gccaaagtcc aatccacagc cgagtctccc ccaccaagaa
    16561 tcgtcacttt tttaccagcg tattgctgaa tgttagaaac gtggtagtgg atattttcat
    16621 agccctcaac cccttcaagt tccagcggac gtggtttgaa ggcaccgcca cccatagcga
    16681 tgataactgt tttagtcagg tgacttcctt tagaagttgt gatggcaaat tcttcttctt
    16741 gtttgtcaat ctcaagaacc gtttcattga gatgaatagg ggtatcaaat ccatttagct
    16801 gttcaatcaa gcggttagtc aactcttctc cagtcaggtt tgggaagcct ggtacgtcta
    16861 ggatttcctt ttcagggtag agaatagcag gttgtccacc tagctgggga agagagtcga
    16921 tgatttgaac cttggcttgg cgtaggtggg cataaaaggc tgcaaaaagc ccgacaggac
    16981 caccacccac aatggtaata tcatagagtt gagacatagt ttctcctttg ttttttctag
    17041 tcagtttatt ttatcatatt tttgttcaat gtaaaatgga ctaggatagg gaaaaaaatg
    17101 ccagaaaatg gtataatagg acgaaagtgt tttgataggg aggatatcag ggatgaattt
    17161 tcaacaatta tccaatttgc aatattggac cagtttgttt gcaagtccat ggacgatagc
    17221 tatcaatctg attgatattt tgattgttgc ttatatttta taccatttta caaaagctat
    17281 tgcaggaacc aagattatga ttttggtacg tggagttttg gtatttattt tagctcaaat
    17341 ccttgcaaat atgattggtt tgactacgat ttcttggtta atcaatcaaa ttattactta
    17401 tggggttatt gcggcggttg ttatcttctc tccagagatt cggactggtt tggaacgttt
    17461 gggaagagcg acagatttct tttccaatgc ccctattagt gctgaggaac agatgattcg
    17521 tgcctttgtt aagtctgttg aatacatgag tcctcgtaaa atcggggcct tggttgctat
    17581 tcagcgtgta cgtaccttgc aggagtatat ttcgacagga attcccttgg atgctaagat
    17641 ttctgcagaa cttctcatta acatttttat tcccaacact cccctacatg acggtgcggt
    17701 gattatcaaa gaagaacgta tcgctgtgac gtctgcctat ctgcccttga caaaaaacac
    17761 agggatttcc aaggaatttg ggaccagaca ccgggcggct atcggtttat cagaagtctc
    17821 agatgccttg acttttgtcg tatcagagga aacgggagga atttcgataa cctataatgg
    17881 aaggtttaag cacaacctaa cacttgatga atttgaaaca gaattacgtg aaatcttact
    17941 tccaaaagag gaagtaggtc ttagttttaa agaacgattg ctaggaggat ggaaacatga
    18001 aaaaaaatag tttatatatc atatcctcac tcttttttgc ttgtgtctta tttgtctatg
    18061 ctacggcgac gaattttcaa aacagtacca gtgctaggca ggtaaaaacg gaaacctata
    18121 ctaatacagt aacaaatgtc cctattgaca tacgctataa tagtgataag tattttatta
    18181 gcggttttgc ttcagaagta tcagtggtct tgactggtgc aaatcgccta tcgctagcta
    18241 gtgaaatgca agaaagtaca cgtaaattca aggttactgc tgacctaaca gatgccggtg
    18301 ttggaacaat tgaagttcct ttgagcattg aagatttacc caatgggctg accgctgtgg
    18361 cgactccgca aaaaattaca gtcaagattg gtaagaaggc tcagaaggat aaggtaaaga
    18421 ttgtaccaga gattgaccct agtcaaattg atagtcgggt acaaattgaa aatgtcatgg
    18481 tgtcagataa agaagtgtcg attacgagtg accaagagac attggataga attgataaga
    18541 ttatcgctgt cttgccaact agcgaacgca taacaggtaa ttacagtggt tcagtacctt
    18601 tgcaggcaat cgaccgcaat ggtgttgtct taccggcagt tatcactccg tttgatacaa
    18661 taatgaaggt gactacaaaa ccagtagcac caagttcaag cacatcaaat tcaagtacaa
    18721 gcagttcatc ggagacatct tcgtcaacga aagcaactag ttcaaaaacg aattaaaaat
    18781 agaaaaggat tttataacaa tgggtaaata ttttgggact gatggagtcc gtggagaagc
    18841 taacctagaa ctaacaccag aattagcctt taaactagga cgttttggag gctatgttct
    18901 tagtcaacat gaaacggaag cgccgaaagt ctttgtagga cgtgacacac gtatttcagg
    18961 ggaaatgcta gaatcggcct tggtggcagg tctcctttca gtagggattc acgtatacaa
    19021 acttggtgtc cttgcaacac cagcagtagc ttacttggtt gaaactgaag gagcaagtgc
    19081 tggtgtcatg atttctgcta gccacaatcc agctcttgat aacggaatca agttctttgg
    19141 cggtgatggc ttcaaactag atgatgaaaa agaagcagaa attgaagcct tgctagatgc
    19201 tgaggaagac actcttcctc gtccaagtgc agaaggctta ggaattttgg tagattatcc
    19261 agaaggcttg cgtaagtatg aaggatacct tgtttcaact ggaactcctc ttgatggaat
    19321 gaaggttgcc ttggatacag ctaatggagc agcttctacc agtgcccgtc aaatctttgc
    19381 agaccttggt gcccaattga cggttatcgg ggaaacacca gacggtctta acatcaacct
    19441 taatgttggt tcaacacatc cagaagccct tcaagaagtg gtcaaagaaa gtgggtcagc
    19501 tattggtttg gcctttgatg gagacagtga ccgcttgatt gctgttgatg agaatggtga
    19561 catcgtcgat ggtgacaaga ttatgtacat catcggaaaa tacctttctg aaaaaggaca
    19621 attggctcaa aatacaattg tgacaactgt tatgtctaac cttggtttcc acaaggcctt
    19681 gaatcgcgaa ggtattaaca aggcagttac tgcagttggt gaccgctacg ttgttgaaga
    19741 aatgagaaaa tcaggttaca accttggtgg tgaacagtct ggtcacgtta tcttgatgga
    19801 ttacaatacc acaggtgatg gtcaattatc agcaattcaa ttgactaaaa tcatgaagga
    19861 aactggtaag agcttatcag agttggcggc agaagtaacg atttatccac aaaaattagt
    19921 taatatccga gtggaaaacg tcatgaagga aaaggccatg gaagtgccag ctatcaaggc
    19981 catcatcgag aagatggaag aagaaatggc ggggaacggc cgtatccttg ttcgtccaag
    20041 tggaacagag cccctcttgc gtgttatggc agaagcgcct acaacagaag aagtggacta
    20101 ctatgttgat actatcacag atgtagttcg tgctgaaatt gggattgact aaatcctaga
    20161 aaactagatg aaaataaaaa attatggtac aatagcttat aatattgtag ccgatggaga
    20221 aagacatgaa tcttaaacgt gaacaagaat ttgttagtca gtatcatttt gatgcacgta
    20281 attttgaatg ggaaaatgaa aatggagctc ctgaaaccaa ggtggatgtg aatttccaat
    20341 tgctccaaca tgaccaagaa aatcaagtga cttccttgat tgtcattttg agctttatga
    20401 ttgtatttga taagtttgtc attagtggaa caatctcaca agtaaaccat atcgatggcc
    20461 gtattgtcaa tgaaccaagt gaattgaacc aagaagaggt ggaaaccttg gctcgtccat
    20521 gtttgaacat gctcaatcgt ttgacttacg aagtgactga aattgcatta gacttaccag
    20581 gaattaattt ggagttctaa tatgaaatta gctgttttca cagattcctc tgcttatctc
    20641 agtgaagaga ccttgcaaag agaagacttg tttgtcttgg atattcctgt caatattgat
    20701 ggtgaggaat atgtcgaagg catcaatctg tctgctgagg aattttacca aaaaatggct
    20761 caggcttctg aattgcctaa gaccagtcaa ccaagtattg ccaagttaga tgagatctta
    20821 acttcgctca aagaacaagg ctatacacat gccttggggc ttttcctatc ttctggaatt
    20881 tcaggttttt accaaaatat ccagtatatg gtcgatgact atgagggctt aaccattgct
    20941 ttcccagaca ctttgattac aagtgctccc ctaggcatca tggttgaaag cgtctttaat
    21001 tggcgtgatc agggcgatga ttttgccagc attcaggata agctagccat tcaaatcagc
    21061 cgtacgtcag cctttatcat ggtagatgac ttggatcatt tggtaaaagg tggacgcctt
    21121 tcaaatgggg ctgccatttt gggcaatttg cttagcatta agccaatcct ttattttaac
    21181 gatcaaggtg tgattgaagt ttacgaaaaa gttcgtactg aaaagaaggc caccaagcgc
    21241 ttaattgaaa ttatcaagga aacaacggct tcaggtcaat accgggtcat tgtcattcat
    21301 gggaatgctc ctgaaaaggc tgaagaattg cgtcagcact tgcttgattt tggcttgggt
    21361 tcggatgttt cacttgctac atttggtagt gtcattggaa cgcacctagg agcaggaagt
    21421 attgctctgg gttatattcc agtgatttag ttggcgcttc taggctagtt aagatgcctt
    21481 gtatcttaga aattgaacac ggactacctg cctcttgaaa aaagatgcct gtcttgcctt
    21541 tcgtggaaag tcagtgccat tccctatttt tcagaggcag ctaaggtcct ttgtatcttg
    21601 ataattgaac acgcctggaa ccctgtgtga aaaagatagt tcttccaaga agtagacact
    21661 tcttgattgg aattcctatt ttcactttgt gttcttacgg actttgtatc ttagacagga
    21721 gtagagatga gtattcgagt aattattgcc ggttttaagg gaaagatggg ccaggctgct
    21781 tgtcagatgg tattgactga tccagacttg gacttggtgg cagttttgga tccttttgag
    21841 tctgagtcag aatggcaggg tattcctgtt ttcaaggata aggctgattt agctggtttt
    21901 gaagcggatg tctgggtaga ttttactact ccagctgttg cctacgaaaa tacacgtttt
    21961 gctcttgaaa atggctttgc tccagtagtt ggaacgactg gtttcacgag tgaagaaatt
    22021 gcagagctaa aagaattttc tcgtgcccaa gacttgggtg gcctgattgc ccctaacttt
    22081 gccttgggtg ctgtcttact catgcaattt gcgacgcagg ctgccaaata tttcccaaat
    22141 gtggagatta ttgagctcca tcatgacaag aaaaaggatg ctccgagtgg aacagccatt
    22201 aaaacagctg agttgatggc agaggttcga gagtccattc agcaaggcgc agcagatgag
    22261 gaagagctga ttgctggtgc tcgtggtgct gactttgatg atatgcgcat ccactcagtt
    22321 cgtttgccag gcttggtagc tcatcaggaa gtcatctttg gcaatcaggg agaagggttg
    22381 accctccgtc atgactccta tgatcgcatc tccttcatga caggagtcaa tttgggaatt
    22441 aaagaagttg tcaagcgtca tgagcttgtc tatggattag aacacttatt atgagattaa
    22501 cgcaaatgcc ttctgaattt cagaaggctt taccagtatt agaaaaaatt aaagaagcag
    22561 gctttgaggc ttattttgtt gggggctctg ttcgagatgc ccttctccat agccctatcc
    22621 acgatgtgga tattgcgacg tcttcttatc cagaagagac caagcagatt tttccgcgaa
    22681 cagccgatat cggaatcgag catggaaccg tcttggtctt agatggggat gaggagtatg
    22741 aggtaacaac ctttcggaca gaggatgtct atgtggacta tcgcagaccc agtgcggttt
    22801 cctttgtacg atcgctagaa gaagacctca aacgccgtga tttcacagtc aacgcctttg
    22861 ccttggatga gacaggagaa atcgttgact tgttccatgg tttagaagat ttggaaaagc
    22921 aagtcttgcg agcagttgga gtggctagtg agcgtttcaa cgaagatgct ttacggatta
    22981 tgcgtggttt ccgttttcag gctagtcttg gttttgcact tgagccagaa acatttaaag
    23041 ctatgaagac cttgacgccg cttttggaga aaatttctgt agagcgtacc ttcgtcgagt
    23101 ttgataaact cttgctggct ccattttgga gaaggggctt ggcttccatg attgagagtc
    23161 aagcttatga ctatctccct gatatggcat ctagccagga caagctcaac agactgtttg
    23221 atttggagac tgattttact tttgaatcct ctgaacaagc ctgggcggct ttactatggg
    23281 ctttggagat tgaaaatgcg cagtcatttt tgaaatcttg gaagacctca cgccagtttg
    23341 ccaagcaagt tcaggatttg ctgattattt tggctctgcg tgaaaatgga gaattgagta
    23401 agcgagattg ttatcgcttt gacatagatt tgcttttaca ggctgaaaat cttcgtcaag
    23461 ctcaaggaaa agaagtcaac ccacaagcca tcacagaaaa ataccaaagc ttgactatcc
    23521 atgacaagaa agagattcag attaatggcg atattttgat caaggaatat ggctatcagc
    23581 caggcccaga cttgggagag attttaacag agattgagtt tgccattgtc gatggagaat
    23641 tggagaataa tcgtgaagcc atccatgctt acctgaggga gaaaaaatga gtgattttat
    23701 cgttgaaaaa ctaagtaaat ccgttggtga caagaccgtt tttagggata tttcctttat
    23761 tatccatgac ttagacagaa ttggtttaat cggtgtcaat gggactggca agaccaccct
    23821 tttggacgtc ctttctggtg tttctggatt tgatggggat gtcagtcctt tttcagctaa
    23881 aaatgattac cagattggtt acttgactca ggatcctgat tttgatgata gaaagacagt
    23941 tttggatacg gttctatcta gtgaactcaa ggaaatccag ctcattcgtg agtatgaatt
    24001 gattatgctc gactatagtg aggacaagca ggcgcgtttg gaacgtgtca tggcagagat
    24061 ggactctctc caagcttggg aaatcgaaag tcaggtcaag accgttctta gcaaattggg
    24121 cattcaagac ttatctactc ctgttgggga attgtcaggt ggtctgagaa gacgggtaca
    24181 gttggcacaa gtcttacttg gcaaccacga cctcttgctt ttggatgagc cgaccaacca
    24241 tctggatatt gcgattattg agtggctgac cctctttttg aaaaattcta agaagaccgt
    24301 cctttttatc actcacgatc gttatttctt agacgctttg tcaacacgga ttttcgagtt
    24361 ggatcgtgca ggcttgaccg agtaccaggg caattaccag gactatgttc gcctaaaggc
    24421 ggaacaggat gagcgcgacg cggctcttct tcacaaaaaa gaacaactct acaaacaaga
    24481 actggcctgg atgcgcagac aaccgcaggc gcgtgcgacc aagcagcagg cccgtatcaa
    24541 tcgattccat gatctgaaaa aggaagtttc aggcagtagt gctgagacag acttgaccat
    24601 gaactttgaa accagtcgga ttgggaagaa agtcatcgag tttcaggctg tttcctttgc
    24661 ctatgaaaac aagcctattt tgcaagattt taatctcttg gtgcaggcca aagaccgtat
    24721 cggaatcgtt ggggacaatg gtgttggaaa atcaaccctg ctcaacttga ttgcaggaag
    24781 tcttgagcca actaaaggac aagttgtgat tggggaaact gttcgcatcg cctatttctc
    24841 tcagcaaatt gagggtttgg atgaaagcaa gagagttatc aattacctgc aggaagtggc
    24901 agaagaggtc aagaccagtg gcggttctac gacttcgatt gcagagttgc tggagcagtt
    24961 ccttttccca cgttcgacgc atggaacctt gattgagaaa ttgtcagggg gtgagaaaaa
    25021 acgtctttat ctcctcaaac tgcttttgga aaaaccaaat gttcttcttt tagacgagcc
    25081 aaccaatgac ctagatattg caactttgac agtcttagag aatttcttgc aaggttttgc
    25141 aggtcccgtt ttaacagtca gtcacgaccg ctatttcttg gataaggtag cgaccaagat
    25201 tctcgctttt gaggatagca agattcgtcc tttctttggt cattacaccg actatcttga
    25261 tgaaaaagct tttgaaacag atatggccaa tcaagtgcaa aaggtcgaaa aggaaaaagt
    25321 ggtcaaggtt cgagaagaca agaaacgtat gacctaccaa gaaaagcagg agtgggcaag
    25381 tattgaaggt gatattgaaa ccttggaaaa acgtatcgct gctattgaag aggaaatgca
    25441 ggctaacggc tctgactttg gtaagctggc tactctccaa aaagaattgg atgagaaaaa
    25501 tgaagcactc cttgaaaaat acgaacgcta tgagtatctc agtgaatttg atagttaaga
    25561 ctattcgaaa atcaaagtgc aaactatgtc ggcttcacat tgccgactca agtacagcct
    25621 gtgaccggct tcctaatttg cactttgatt tttattgagt ataaaagaat agaaaaatcc
    25681 cgtctcatga aaggatttct ctattctttt ttggtttctt gatgaaagat attttgccag
    25741 gtttcgtggc gacgccagat actggtatgg atgataccat ctaactcata gcagatgagt
    25801 ttggtttttt gactgatgga agtaatttga atgtccttga tagcagaatt taactctttt
    25861 ttggtcttat aagcctcttt atccatctgc tctccatctt ggcgaatata gacaaaatca
    25921 tcagtcaaga gttcttctag ttggtttcct tggtcaatca attgttcacg cataagcaat
    25981 tttttataga cattgtctaa aatttcatcc tcagagatag gtgctggttc gatatggaca
    26041 tcggtatcaa agacgccaaa acgctcctcc agcatagact cgacctgatc cgcgatttca
    26101 tggctttcaa aaacagacaa gtcaggattc atctctagtg taatatccag gtagatgttg
    26161 ctaccgtagg tgcgacctct ttgcgatttg accttgctga ttttgggaat ttccatgata
    26221 gccttttggt agtcctcgag caggcggtcg tcaaagccat ctgaaagact aaaggaagac
    26281 tcgatgaaga tatcataggc agtcttcaag ataaagaaag tgatgatgat agcaaccagt
    26341 ttatccacaa tcggataatt gaaactacta gctaggatgg caatggcggt tccaagtgag
    26401 gtaacagcgt cagaaagatt gtccttagca gctgccttca gcgccttgga gttggatttc
    26461 ttactgaggc gagtattgta gagatagacc acaaacataa tcgctgcaga aatgattcct
    26521 agagttgcac caagaggatc aatgaccgtt tcttcccgac tgagaatctt ttgaatggta
    26581 tctcttagaa catcgaaacc gacatagaac atgatgatag aagtgatcaa gcttgccaaa
    26641 tcttcaatct tccaatgacc aaaacggtgg tcacggtctg caggctggcg cgccatccga
    26701 atcccgatta agagggccac atttccaatg atgtccgata cgttattaaa accatcggcc
    26761 accaaactgg atgaatgaag gagatgacca gctgctaatt tggctgcaga caagatcaaa
    26821 taggtcgaaa tactgataat ggctccacgc tcagctaact tgagatttga gatagattgc
    26881 ttcattcaac ttcctttcta gtcacatagc attctaccat tatactggtt ttcaaggaaa
    26941 aattcaaata aggcagtttt tactctttga aaactcccca aaatttggta taatggtact
    27001 actcaaggga gtagctggca gaaacctgtg atagtgtcgt cattccgaat tttatgctga
    27061 aaagtatgct ttccggccct atcttaaaca gcgagacttg ttatgattaa caggtctctt
    27121 tttgtttgtc gtgaaaagat atgacagaaa gagagtctgt tttgcacaca atgtcaagga
    27181 ggagacacat gtcaaaagaa caaaaacgcc aagcgtttta tactcagagc cctgaagagg
    27241 tcttgcaggc tgtggatgcg accgagcaag gtttgtcatc aagtgaggcg gaaaagcgcc
    27301 ttgctgaatt tgggcacaat gaactcgaag aaggcgagaa acgatcaatc ttggtcaaat
    27361 tcatcgagca atttaaggat ttgatgatta tcatcctagt tgcggcagca atcttgtcag
    27421 tcgtgacttc tggtggggaa gatatcgcag atgccattat catcctagct gtggttatca
    27481 tcaacgctgc ctttggtgtt taccaagaag gaaaagctga agaagctatt gaagccctca
    27541 aatccatgtc tagtccagtt gcccgcgttc ttcgtgatgg acacatggca gagattgact
    27601 ctaaagaatt ggtaccaggc gatatcgttg cccttgaagc aggtgacgtg gtaccagcgg
    27661 acctacgttt gatagaagcc aactctctta aaattgaaga agcagccttg acaggtgaat
    27721 ctgtaccagt cgaaaaagac ttgtcagtcg agcttgcgac agatgctggt attggtgacc
    27781 gtgtcaacat ggccttccaa aactcaaacg taacctatgg tcgtgggatg ggtgttgttg
    27841 tcaatacagg tatgtacact gaagttggtc atattgctgg tatgcttcaa gatgcggatg
    27901 agactgatac accactcaaa caaaatttga acaacctttc taaggtcttg acctatgcta
    27961 tcttggtcat tgcccttgtt acttttgtag tgggtgtctt cattcaaggg aaaaatccac
    28021 ttggtgagtt gttgacttct gttgcccttg ccgttgcagc cattccagaa ggacttcctg
    28081 ctatcgttac catcgttctt tctcttggta ctcaagtttt ggccaaacga cattccatcg
    28141 ttcgtaagtt gccagcagtt gaaacacttg gttcaactga aatcatcgct tctgataaga
    28201 ctggtacgct gactatgaac aagatgacag tcgaaaaagt cttctacgat gcggttctac
    28261 atgactcagc tgatgatatt gaactaggtc ttgaaatgcc actacttcgt tcagttgtct
    28321 tggccaatga tacgaaaatc gatgtggaag gtaacttgat tggtgaccca accgaaacag
    28381 cctttatcca atatgccttg gacaagggct atgatgtcaa aggtttctta gagaaatatc
    28441 ctcgtgtagc tgaattgcca tttgactctg accgtaagct catgtcaaca gttcacccat
    28501 tgccagatgg tcgtttcctt gtagcagtca agggtgcgcc agaccaactc ttaaaacgtt
    28561 gtcttcttcg tgataaggct ggggatattg ctccgattga tgagaaggtt acaaatctca
    28621 ttcatacaaa caattctgaa atggctcatc aagccttgcg tgtccttgca ggtgcttata
    28681 agattatcga tagtattcca gaaaatctca cttctgaaga gcttgaaaat gatttaattt
    28741 ttactggttt gattgggatg attgaccctg aacgtcctga agccgctgag gctgttcgtg
    28801 tggctaagga agcgggaatc cgtccaatta tgattacagg tgaccaccaa gacacagcgg
    28861 aagccattgc caaacgtttg ggaatcattg acgcaaacga tacagaaggt cacgttttaa
    28921 ctggtgctga actcaatgaa ctgtcagatg aagaatttga aaaagtcgtt ggtcaatact
    28981 ctgtttatgc ccgtgtgtct ccagaacaca aggttcgtat cgtcaaggct tggcaaaaac
    29041 aaggtaaagt cgttgccatg acaggtgacg gtgtcaatga cgcgccagct ctgaaaacag
    29101 ccgatatcgg tatcggtatg ggaatcactg gtacagaggt ttctaagggg gcttctgata
    29161 tgattcttgc agatgataac tttgcgacta ttatcgtcgc agtggaagaa ggacgtaagg
    29221 tcttctcaaa cattcaaaag actattcagt acctactttc tgctaatact gctgaagtat
    29281 taaccatctt cctatcaacc ttgtttggtt gggatgtctt acagccggtt catcttttgt
    29341 ggattaactt ggtaacggat accttcccag ctatcgctct tggtgttgaa cctgcggaac
    29401 ctggtgtcat gaatcataaa ccacgtggac gcaaggcaag cttcttctca ggtggtgttt
    29461 tgagttctat catttatcaa ggtgtactcc aagcagctct tgttatgagt gtttatggcc
    29521 ttgcgattgc ttacccagtt catgtgggtg acaatcatgc tattcatgca gatgccctaa
    29581 cgatggcctt tgcaaccctt ggtttgattc agctcttcca tgcctacaat gtcaagtctg
    29641 tctaccaatc catcttgaca gttggcccat tcaagtctaa gacctttaac tggtccatct
    29701 tggtatcctt tatccttctc atggcaacaa tcgttgtaga accgcttgaa ggaatcttcc
    29761 acgtaaccaa actagacttg tcacaatggg gaattgttat ggctggaagc ttctcaatga
    29821 ttatcatcgt cgaaatcgtt aagtttattc aacgcaaact cggttttgac aagaatgcga
    29881 tttaagggag gtttcggatg tcagcatatc aattaccgac cgtatggcag gatgaagcta
    29941 gtaatcaagg agcttttacg gggctaaaca gaccaacagc aggtgcccgt ttcgaacaaa
    30001 acttgccaaa aggagaacaa gcttttcagc tttattcact gggaacacca aatggtgtga
    30061 aggttactat cttattggaa gaattactag aagctggttt taaggaagcg gcttacgact
    30121 tgtataagat tgctatcatg gatggggatc aattcggctc agactttgtg aagctcaatc
    30181 caaattccaa gattccagcc ttattggacc agtcaggtac tgaaaacgta agagtctttg
    30241 agtctgctca tattcttctt taccttgctg agaaatttgg agccttttta ccaagtaatc
    30301 ctgtggaaaa ggtagaagtt ttgaattggc tattctggca agcaggtgca gcaccttttc
    30361 taggtggggg atttggacat ttcttcaatt atgctcctga aaaattggaa tatcctatta
    30421 accgttttac gatggaagtg aaacgccagt tggatttatt ggataaggaa ttggctcaga
    30481 aaccttatat tgcaggcaat gactatacga ttgcagatat tgctatctgg tcttggtatg
    30541 gacagttagt tcaaggaaat ctttaccaag gttctgcaaa attcttggat gcctcaagtt
    30601 atcaaaatct agtaaaatgg gcagaaaaaa ttgccaatcg tccagctgtt aagcgtggct
    30661 tggaagtaac ttatacagaa attaaatagc aaaaaagtca tcttcggatg gctttttgct
    30721 acagttgagg gaaagggttt gcagttatcg gcttttgtgc tataattgct ataatatagt
    30781 aaaaagcaag aggagtgtga ggaagtggaa aagaaaattg tgaaggatat cttattttta
    30841 tctcaagtgt ctcatccggc aagtcaggag gacctttatc ttgccagaga tttgcaggat
    30901 acactcttag caaatcgtga tacctgtgtt ggtctagctg ccaatatgat tgggatgcag
    30961 aagcgcgtga ttatctttaa tcttggcttg gttcccgtgg tcatgtttaa cccagtgctt
    31021 ctgtcctttg aaggatccta tgaggcagaa gaaggctgtt tgtccttggt aggtgtgaga
    31081 tcaactaagc gttatgaaac cataaggctt gcctatcgtg acagcaagtg gcaggaacag
    31141 accattacct tgacaggctt cccagctcag atttgccagc atgagctgga tcacttggaa
    31201 ggacgaatca tttaggagga aagcaaatga aacgaatagt ctttgaactt atttttatcg
    31261 caacgacctg gtatatcttt ttaccgcccc ttaacctgac cagctgggaa tttctcttct
    31321 tcctctgtgg gcatttgtta gttgtggcaa tcttatttgg ctttggcaag gggataaacc
    31381 ttgtcaaaac ggttcatgtg cgccacggta aggcggaagc tgccttaaat cttgagggtt
    31441 tcaaaatcaa tcggttaggg aaaattctgt tagcttcgat tggaggaatt cttctcttgg
    31501 cagctttggt ttccttggta acttctagca tgtttcaggc taaaaattat gccaatgtag
    31561 tcacggttac ggaaaaagac tttactgaat ttcctaagag tgacaccagt aaggttccta
    31621 tcctagatag aagtactgct gaaaaaattg gagaccgcta cttgggttcc ctaaccgata
    31681 aggtgtcgca atacgtagcg gcagatacct atacccaatt gacaattgat gggaaacctt
    31741 atcgggtcac accactagaa tatgcagacc ctatcaaatg gtttaacaat caagccaagg
    31801 gaatcggtga gtatatcaag gtggacatgg taactggaaa tgcggatttg gtggacttga
    31861 agacaccaat caagtattca gactcggagt attttaaccg tgatgtcaaa cgtcacctgc
    31921 gcttgaagta cccgaccaaa atctttaaaa ctccatcttt tgaggtggac gatgagggca
    31981 atcctttcta tgtagcaacg gtttaccaaa agcaatttgg acttgctgtt cctcgtcctg
    32041 cttcagtcat tatcttggat gctacaaatg gagaaaccaa ggaatacagc ttatcagatg
    32101 ttccagaatg ggtggacagg atctatccag cagaggaaac cattgagcaa atcaactaca
    32161 acggcaagta caaggacggt ttcttgaatg ccatgatttc caagaaaaac gtgacccaga
    32221 cgaccaatgg ctataattac ttgtctatcg gtaatgacat ctatctctac acaggtgtga
    32281 cgtcggctaa tgcggatgag agtaatcttg gtttcatcct tgaaaatatg cgaacaggag
    32341 aaattactaa gtatagcttg gcttctgcga cagaagaatc agcccgtgaa tcagcagaag
    32401 gtgctgttca ggagaaatcc tacaaagcaa ccttcccaat cctcatcaac ctcaatgaca
    32461 agcctctcta catcatgggc ttaaaggaca atgctggctt ggtcaaagag tacgccctgg
    32521 tagacgcagt cgagtaccaa aatgttatcg ttgctactac agtggaagag atgctcagca
    32581 agtatgccaa taaaaacgac cttgaaattg acaatgcaac gacagaaagc atcaagggag
    32641 tagtagcaga cctcaaatca gctgttatca agggagacac tgtctacttc tttaaagttg
    32701 atggcaagat atacaaggta aaggcttcag tatccgatga ccttccttac cttgaaaatg
    32761 gtaaaacctt cgaaggtcaa gtaggaaaag acaattatct caagaccttt aaagtacaat
    32821 aatactcttc gaaaatctct agctctatct gcaacctcaa aacagtgttt tgagcagcct
    32881 gcggctagtt tcctagtttg ctctttgatt ttcattgagt ataaaaaagg tttatttaat
    32941 aaatatatgt tataataagg taaattaagc ctaatggagg acaaagaaat gggtttttat
    33001 ttgatggttg cttcaatgct actcggactg ctcgctttga agataggttt ttctcagttc
    33061 aaggagaaaa aagataaatt cttatctatc ttaacaagtt tagctggcac agcccttgtt
    33121 ctcgtggctg tctggttagg atggcccaaa taaatagaaa aacctcggtc aaaccgaggt
    33181 ttttcaaatg aatttcttgg ttgtggctaa aaaatatgct acactatcaa tatgaaaatt
    33241 ttaatcccaa cagcaaaaga aatgaacaca gacttgccaa gtatcgaggc aattccttta
    33301 aaaccagaaa gtcagaccgt gcttgatgcc ttggctctct attctgccag tcaattggag
    33361 agtttctaca aggtatcagc tgagaaagcg gcggaagaat ttcaaaatat ccaagctttg
    33421 aaaaggcaaa ctgctcaaca ctatccagcc ttgaaacttt ttgatgggct tatgtaccgc
    33481 aacattaaga gagataagct gaccgaggcg gaacaagatt atcttgaaaa tcatgtcttc
    33541 attacctcgg ctttgtacgg tgttgttcca gccttgtcac ccatggctcc tcaccgtttg
    33601 gattttttga tgaaattaaa agtcgctggt aagactttga agagccattg gaaggcagtc
    33661 tatgatgaag ctctgaagaa ggaagaagtg attttctctc tcttgtcatc agagtttgag
    33721 actgtatttt ctaaggaaat cagagcaaag atggtgacct tcaaattcat ggaggataga
    33781 ggcggtcagc tgaagattca ctcaactatc tccaagaaag cgcgcggggc ctttctaaca
    33841 gctttaatag aaaatcaagt acaaactgtg ggggaagcac gtcgcttgaa ctttgctgga
    33901 tttgtttacc gagaagattt gtcacaacca cagggattgg tttttgtaaa ggaagtatag
    33961 aaatcagata agagaaaagt cagcacgatt atgctgactt ttttgataac ttataaagta
    34021 ttggacaaat gaatctcatt tgataaggtg ttaagatgat taaccaaatt catgattgac
    34081 agatgatttc ggcaaataaa cttcttggta atccctgaaa tatagaaatt agacacgatg
    34141 atatcgtaat ctgtctgatt taaaatctca ggacttgttt ttaattcatc ccaaatatcg
    34201 aaggtaaagc ggttattaca gtaataggaa agcatatcaa caaaggtaag ggatatagca
    34261 tggtcaaagt tactgataat caaaaccttg ataggtggtc gattttctaa caactgagta
    34321 gagaggtttt cagcatgggt taagatggtg tacatcaagt gttccaactg ttcaggatgg
    34381 tcatgctgtc caattgcctg acggtattga gccagttctt gacgcgcact tcccataaag
    34441 tctgggaagt aaccttcaaa ttttttaatc gtcaatgctt tttgttcaaa taagattggg
    34501 gtagaaaaga tttcctgtct ttcaaagaaa gcagtgttgt gtaaatgcca aatcagctca
    34561 tcgtggttag taaaagtaat cttatattgt tttgataggc gttctaatat ttgactaagt
    34621 aattggtaag agtatcttgc ttgactgtta tcttctaaag agttgaagaa ttcttgagga
    34681 tctaggaaaa tatcattctg aagaaaagaa ataaaaattt gagcgattgt atctggagtc
    34741 atttcaagcc caaaatgttt agagaaataa gcaagtgtct cctggaaatt tggaatgctc
    34801 tttaaaagag gataatattc tttgtaaaag tggttgggga ggtcaatgaa gtgaccattt
    34861 ttaaccctgt ggatactgat agctatcatc agtttgtaca ttctataaat tgaaaatcgc
    34921 attggataat tcgtgatttt atagaagaag tcagcaaact ctgttaaatc ttcctcagga
    34981 aggtcaggaa aaggccaatc taggaaataa tagcgctcag aaaagtattg ggcaaaaaag
    35041 taacgaatat cgatctcatt tccacgtatc tcggatggag taaaagataa ttcaatttga
    35101 aactgagatg aaagaacctt tgtaatattt ctgcccagtc gatagaggtt ggcactacta
    35161 aagtaaagat tttctattgt tcgataaata ggtagcccct cattgaagaa catatactct
    35221 agtaattgaa aagattgaga attagcaaga aaatattgat aaatatcttc tacactagtg
    35281 ttaacttcta aatctatcat gattccgtta acagaagatt ggatgttaat agatggaaag
    35341 gcaatacgta attcatttaa atcacttttt aagattcgtt ctgtacatcc taatttttcg
    35401 gctagttcat gtaatttcat ccaattacga ttctgaatta gggtttccat taagcgtaat
    35461 tgtctttgaa cttttgtgga taaaaggttt ctcatacggg tatttcctcc ataattcatt
    35521 atatcttttt ttgtctaagt agtataaaaa aattagagca agaaaattgt cgttagtaat
    35581 cggaaaaatt agaataatat aagtggcttt taagtgcaaa aacagaatat attaattgtt
    35641 cagaaaatat tgattaatgc ctcaaatagt tgtacattgt aaactataaa atactatcta
    35701 ggagtttaaa atgaaacatt cacataaaaa atcatttgac tggtatagca tgcaacaacg
    35761 ttattctatt cgtaagtatt actttggtgc agttagtgtc ttgctcggta ccgctttggt
    35821 attaggtgca gcagctagtg tccaaacagt acaagcggaa gaaaacaaac aagaaactac
    35881 caatagtatt tctgttggta ggggagaagc agctactaaa ccagcagagg tttctgcgtc
    35941 taataaagag aaaacctatg cagctccaac tgtagctaat ccagtagaaa cgactccagt
    36001 taaaactgga gaagttacta aaccagcaga aaaagttgaa gaagcaaaag acaaaaaaga
    36061 ggaagtaacg catcaagatg ctattgacaa gtcaaaattg ttaacggctc tttcgcgtgc
    36121 taaaaagtta gaaagcaagt tatatacaga agcaagtgct gctaacttgc aaacaagtat
    36181 ccaagctggt caaagcttgc ttgggaaagc agatgcatct gaagctgaat tatcagcagc
    36241 agagtcatct attcaatcat ctattattgg tctagaactt cgttctaact ctaacaaagg
    36301 aactgtatca gaaactcctg tagcgaagaa agctaatata gttgaagcga aggaagagac
    36361 taatccagct gcaacaactg atcgttcagc tgttgatagt gctgttttgc caactagcac
    36421 agctgccaaa gtagaaacaa cttcagctcc agcatctatt aatgaaatct tgaaaccagg
    36481 tttgagcctt tctgatgctc gccaaaatcc agctatccgt aaggaagatg ttgatagagg
    36541 gtatagtggt tttagagcgg cgcctgctcc aacgaaccaa ccagtaacta atctaggaaa
    36601 taatactgtt ttcactgata ttagcagagg ttctcatact ttccgtggta atggaaattc
    36661 acgtcgtgga aacccgattc attttgatgt aacaacaact agagttagaa atagagtaga
    36721 tttctcaatc agatattcag gaccaggtga gtttgttaat aacaacttta tcttagacaa
    36781 aggaaatgga ttcggagaac cttctcgtgc aactgtttca acaccaaaat taagagacca
    36841 agttaaaaac attagtaagg gtggaaactt tgtttctcat tcaggctaca gtttagaagc
    36901 tgcagtagaa acaagcacca atcaaacaat taagtttagt ttacctatag ccaaccctaa
    36961 tggtgatctg tctgttcgat taagacctgt tacttttaat gtaggtcaag gggaatcagg
    37021 atctgcaact agtaatgatc catatagtaa ctctaactat tacttcagag aaaaaccact
    37081 cctcttggat gcaaatccaa atggtggtac taataataag actgtttcag aagacattga
    37141 cttccaaact gtctatcttc caactagtaa gttaccagaa ggtcaaacta gattagttcg
    37201 agaaggtgaa aaaggacaac gtcaaatcat ctataaagtt catcaattgg gtaacgaaac
    37261 aatcctagga ttgccaatta gtaattcagt tattaaagaa gttaagccac gtattatgca
    37321 aattggtgtg gctaaagatc taatcgatac agtaaaacca cgtgttgatc aaaataaagt
    37381 cggtgataca aataacctca ctttctatct tgataacgat ggaaacggtg tttatactga
    37441 gggcgtagac gaacttgttc aaaaaattgc tattaaagat ggtgctaaag gtgaaaaagg
    37501 agaccgaggc gaacgcggtc taactggagc tcaaggagct aaaggtgaaa aaggagaccg
    37561 aggtgaacgc ggtctaactg gagctcaagg agctaaaggt gaaaaaggag accgaggtga
    37621 acgcggtcta accggagctc aaggagctaa aggtgaaaaa ggagacc
//
LOCUS       DAVAZV010000015        37450 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVAZV010000015 DAVAZV010000000
VERSION     DAVAZV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37450
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.015"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..775)
                     /locus_tag="VQT46_000745"
     CDS             complement(<1..775)
                     /locus_tag="VQT46_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2370803.1"
                     /translation="MSKETVVYTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMV"
     gene            complement(871..2181)
                     /locus_tag="VQT46_000746"
     CDS             complement(871..2181)
                     /locus_tag="VQT46_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET2370804.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            complement(2308..3303)
                     /locus_tag="VQT46_000747"
     CDS             complement(2308..3303)
                     /locus_tag="VQT46_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2370805.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFGGDKTTKKI"
     gene            complement(3665..5146)
                     /locus_tag="VQT46_000748"
     CDS             complement(3665..5146)
                     /locus_tag="VQT46_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2370806.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            5589..5753
                     /locus_tag="VQT46_000749"
     CDS             5589..5753
                     /locus_tag="VQT46_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2370807.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            5837..6403
                     /gene="amaP"
                     /locus_tag="VQT46_000750"
     CDS             5837..6403
                     /gene="amaP"
                     /locus_tag="VQT46_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET2370808.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            6415..6585
                     /locus_tag="VQT46_000751"
     CDS             6415..6585
                     /locus_tag="VQT46_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET2370809.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            6624..7232
                     /locus_tag="VQT46_000752"
     CDS             6624..7232
                     /locus_tag="VQT46_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET2370810.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            7263..7466
                     /locus_tag="VQT46_000753"
     CDS             7263..7466
                     /locus_tag="VQT46_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2370811.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7576..7854)
                     /locus_tag="VQT46_000754"
                     /pseudo
     CDS             complement(7576..7854)
                     /locus_tag="VQT46_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            8064..8339
                     /locus_tag="VQT46_000755"
     CDS             8064..8339
                     /locus_tag="VQT46_000755"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2370812.1"
                     /translation="MKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSKWKDI
                     SNHHDSESFFANLGCSRQRRLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(8617..9387)
                     /locus_tag="VQT46_000756"
     CDS             complement(8617..9387)
                     /locus_tag="VQT46_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET2370813.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(9402..10250)
                     /locus_tag="VQT46_000757"
     CDS             complement(9402..10250)
                     /locus_tag="VQT46_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
                     /protein_id="HET2370814.1"
                     /translation="MKMKKIKGGTFMMGTNSEEGFLDDFEGPQVAVSVKDFSIADTPV
                     TNQEFAQFVKETGYKTLAERQEWSFVFILFVPEAEREGYPHPAGAPWWLQVPNACWKH
                     PYGENSNLVGLEDHPVVHVALEDALAFCNWSGMSLPTEAQWEYAARGGRQSEYPWGDT
                     LLEGGYYHANTWQGRFPYENTALDRFIGTAPVYEFLPNDFGLYQMIGNVWEWCRNPRY
                     TLLASFNEDDYELPKYGIQDEEYAIRGGSFLCHCSYCNRYRVAARNGCISTSTSSHLG
                     FRCLKE"
     gene            complement(10247..11722)
                     /locus_tag="VQT46_000758"
     CDS             complement(10247..11722)
                     /locus_tag="VQT46_000758"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HET2370815.1"
                     /translation="MVQTKQPNIILIVVDQMRADALSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYVSDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTSLKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(12045..13400)
                     /locus_tag="VQT46_000759"
     CDS             complement(12045..13400)
                     /locus_tag="VQT46_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2370816.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMADKTEL
                     S"
     gene            complement(13410..13727)
                     /locus_tag="VQT46_000760"
     CDS             complement(13410..13727)
                     /locus_tag="VQT46_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2370817.1"
                     /translation="MDESNLESVMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTREAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(13744..14061)
                     /locus_tag="VQT46_000761"
     CDS             complement(13744..14061)
                     /locus_tag="VQT46_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2370818.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(14074..15759)
                     /locus_tag="VQT46_000762"
     CDS             complement(14074..15759)
                     /locus_tag="VQT46_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HET2370819.1"
                     /translation="MKNKKLISSLFILFLLIFIHVKVFANENLIKNSNFEQGELFWNS
                     RNRGIINSNESYSNGHYSGMIPSTAINDNRADGYIGQVIDIEPNEDYLVSAFAKVDIS
                     GAEGYFTARWFDNNKQGEIVQNNIGEAVDQTVNTTEWKKYMFSFNSGKHDKVLIQLVK
                     WSEDDTTKKSNIFIDNVEMYQLSKGNSYKKIWRDDFDGEQLNKKYWGYELGSIRGWEQ
                     QHYVRSDENVFLRSGNLVLRATNRSKEDQYFNPRNNHRKVVYNSGSVRTHGKVEFLYG
                     KLEMRAKLPKGQGVFPAFWTLGSDFTLDGKINPVQGRGWPSTGEIDIMELVGERNSNG
                     SGNKTVYQTLHYGQSDNDDGKFAGRGTAFKLSSGNFNDSYHTFSIDWYKDYIVWMVDN
                     HIVRKVYYGSDNIAKKIFNRPQYVQLNLAMGGSWPGVVDNNLSGTEFVVDYVSYSRND
                     LQQHQAEEYYSQSPKINGAKDIVINRGDVPDLLKGITTNSGYELDYSIENEPMFNNFG
                     GNTSVDLLIRNKTEKEKISQMPPGVYNLHYTSRPKHLDYESKVDRKTVTLTIK"
     gene            complement(15764..16660)
                     /locus_tag="VQT46_000763"
     CDS             complement(15764..16660)
                     /locus_tag="VQT46_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET2370820.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(16663..17925)
                     /locus_tag="VQT46_000764"
     CDS             complement(16663..17925)
                     /locus_tag="VQT46_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2370821.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFITGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQGALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPSWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            18205..19383
                     /locus_tag="VQT46_000765"
     CDS             18205..19383
                     /locus_tag="VQT46_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2370822.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(19611..20057)
                     /locus_tag="VQT46_000766"
     CDS             complement(19611..20057)
                     /locus_tag="VQT46_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370823.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGPRIPFLLPLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQEQDLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVRKYSGLKLE"
     gene            20127..20786
                     /locus_tag="VQT46_000767"
     CDS             20127..20786
                     /locus_tag="VQT46_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET2370824.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLL
                     V"
     gene            complement(20838..21989)
                     /locus_tag="VQT46_000768"
     CDS             complement(20838..21989)
                     /locus_tag="VQT46_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET2370825.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNITIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(22004..22735)
                     /locus_tag="VQT46_000769"
     CDS             complement(22004..22735)
                     /locus_tag="VQT46_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370826.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WTRPNHIDTAFASADLFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFP
                     LVQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNS
                     NIEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDI
                     PNFSELSETEDFEIIPRIEKQEGQK"
     gene            22964..23065
                     /locus_tag="VQT46_000770"
                     /pseudo
     CDS             22964..23065
                     /locus_tag="VQT46_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            complement(23037..23813)
                     /locus_tag="VQT46_000771"
     CDS             complement(23037..23813)
                     /locus_tag="VQT46_000771"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET2370827.1"
                     /translation="MPKTLTKKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(23806..25029)
                     /gene="trpB"
                     /locus_tag="VQT46_000772"
     CDS             complement(23806..25029)
                     /gene="trpB"
                     /locus_tag="VQT46_000772"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET2370828.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDLTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGAEAAGFGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(25007..25606)
                     /locus_tag="VQT46_000773"
     CDS             complement(25007..25606)
                     /locus_tag="VQT46_000773"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET2370829.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVAADLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQSFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(25593..26360)
                     /gene="trpC"
                     /locus_tag="VQT46_000774"
     CDS             complement(25593..26360)
                     /gene="trpC"
                     /locus_tag="VQT46_000774"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET2370830.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDC
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNTGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            complement(26357..27361)
                     /gene="trpD"
                     /locus_tag="VQT46_000775"
     CDS             complement(26357..27361)
                     /gene="trpD"
                     /locus_tag="VQT46_000775"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET2370831.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEDYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(27372..27938)
                     /locus_tag="VQT46_000776"
     CDS             complement(27372..27938)
                     /locus_tag="VQT46_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET2370832.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(27935..29296)
                     /gene="trpE"
                     /locus_tag="VQT46_000777"
     CDS             complement(27935..29296)
                     /gene="trpE"
                     /locus_tag="VQT46_000777"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET2370833.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQAIDRDPLDFLYEVTHKSQHHSDLPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRSVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(29797..29874)
                     /locus_tag="VQT46_000778"
                     /pseudo
     CDS             complement(29797..29874)
                     /locus_tag="VQT46_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(30479..31480)
                     /locus_tag="VQT46_000779"
     CDS             complement(30479..31480)
                     /locus_tag="VQT46_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2370834.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            complement(31588..31956)
                     /locus_tag="VQT46_000780"
     CDS             complement(31588..31956)
                     /locus_tag="VQT46_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370835.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKCYIDRLLYVFINPTHFTEKVNLQFYGSFFSYEFICREVGN
                     ILKNKGVKCNLNFFEGEEYL"
     gene            complement(32052..32762)
                     /locus_tag="VQT46_000781"
     CDS             complement(32052..32762)
                     /locus_tag="VQT46_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET2370836.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            complement(32765..34456)
                     /locus_tag="VQT46_000782"
     CDS             complement(32765..34456)
                     /locus_tag="VQT46_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2370837.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDPNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            complement(34468..35478)
                     /locus_tag="VQT46_000783"
     CDS             complement(34468..35478)
                     /locus_tag="VQT46_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370838.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            complement(35581..36648)
                     /locus_tag="VQT46_000784"
     CDS             complement(35581..36648)
                     /locus_tag="VQT46_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2370839.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVK"
     gene            complement(36673..37332)
                     /locus_tag="VQT46_000785"
     CDS             complement(36673..37332)
                     /locus_tag="VQT46_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET2370840.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
BASE COUNT        12046 a         7633 c         5729 g        12042 t
ORIGIN      
        1 acaccatagt aattgttgag tttaatgggc caccttgcgt cataaccatt ggttgtacaa
       61 tcagcttaaa agcagaaatt aaagttgtta acaatacaaa cagggctgtt ggttttagta
      121 ggggcatcgt gatataacga aactgagccc attttgagaa tccatctaat tcagcagctt
      181 catagacatc ttgtggaata ttctgcattc ctcctaaaaa taaaagcatc tgataacctg
      241 caccctgcca agcagaaaca aaaacaattg catacatagc ttgtttagga ctagtcaaga
      301 aaggttgaga agcaatacct accttattta aaatagcatt taataagcca ctatttggat
      361 ttaaaagata aagccaaaga atagaaataa ctaccaagga catgacaact ggagcaaaaa
      421 aagccacttt aaaaaacata tttccttttc gctttttatt gacaatcaaa gccattccta
      481 aggccgctcc caattgaact ggaataatcc aaacaacaaa tttcaaagta ttcaagaagc
      541 tctttaagaa aatcggatct tttgttaatc gaataaaatt ttcaagtcca acaaattttc
      601 tttcatctgg tgtcaacaaa taataatctg taaaagcgta ataaatgacc attccaactg
      661 gaattactaa aaagatacct aataaaatta aagctggagc taaaaaacta taacctaata
      721 tgttatcctt tattttttca cgtctttttg tatacacaac agtttcttta ctcatatcca
      781 tctcctttaa tcatatatat caaactaggc tattaacaag aaaggggaag gtagttccaa
      841 acattttcct tccaccttct tttttacaga ttatttgagt gactgatcaa tagcagtttg
      901 catttctttt gtacgagtat ccaagacttt ttgcacattt ggattttctt cataatagct
      961 aatatcttgc attgcttgtt gaaaagctcg agaaacctga ggatatgcta cgacaactgg
     1021 gcgagcatga gctgtttttg aattttgttc catcaagaaa cgcattggtt cggatacttt
     1081 atctttgata ttttcaattg tagatttacg aattggaagg accgaattcc ccaagctaat
     1141 aatttcactt gattctgtat ttgtagcaaa tttaacaaat tcagatgcgg cctctttttt
     1201 atcagatttt gtcgtcacag ctaattgcca actacctgaa ggggatacta attttttcgt
     1261 cttactagat actgggtaag gaaggatacc aaaatcaata tctttgtagt ttgtattcat
     1321 gtcagcaatc gtccaagaac cactcaaaag cattggatac tctcctgttt caaaaccttt
     1381 ttcgactgga ctaacagttg tatagccttc ttttacaaga ttttgaatga attgaactgc
     1441 ttctacactc tctttggagt tgaagtatcc ttctgccttt gttccatctt cgtttacgac
     1501 agaaccatta tttgaccaaa tcaacggcat ataagcatat ggcaacattt catcgtttga
     1561 attaatacga aaatcaattg ctggtttgtt ataatgatct ttcaattttt tagcaatcgt
     1621 attaaattcg tcccatgtcc atggcttttc tagcgttgga agctctgatt ccgcaattcc
     1681 agcctctttg aacatttttt tattgtaata aacaccaaca ttcgattcag aaaatccaaa
     1741 tgcatagaat ttcccattat aagttccctg ttgtttaata ctgtccaaaa catcatccat
     1801 attattatct tttagataat catctagcgg agtaattact ttagattttg cataagctgc
     1861 cgtatttggt ccatcaaggg taataacatc tggaagacta ttagtcgtaa tagcagcatt
     1921 aaccttgtct tcatatcctc caccactacc actacgagga atatactcag ttacaacctt
     1981 gtacttactt tttcctgatt gattaaagtt atcaacaact ttttgccaag cttttccttc
     2041 atttgtttcg tcagagaatt gtacccagac tttaatatca tttgaagaac tcgcttgttt
     2101 tgagttagtt cctccactac aacctgcaag tatagctaac gatagccccg caacaacaga
     2161 taacattgta cctttacgca tcatttttct cctttttgaa acgtttcatt ttttatttat
     2221 tttttaaaca agcttctagc ctatttttga aacgtttcat ttgttgatta tattataaca
     2281 gcgctttcat taattgtcaa gcgcttttta aatttttttt gttgttttat ctcccccaaa
     2341 atatgtggga attacgattc gtttttctag aatctcttct cgcttaatca ttttcagtat
     2401 cattgcaaca gattcttttg ccatcatacc aatatcttga actattgtag acactagata
     2461 agattgatcg acagaagttt ttaaaccatc aaacccaatt atctggtaat catcaggtgc
     2521 tattttcccc agttctttca taacactaat aactctcaga gccatcatat catttattgt
     2581 aaatatacca tcaatttctt tatgagattg caaaaaaatt cttatctgat cttcaggatt
     2641 tattaaaggt tctttcattt caaaattata gacatctact cctaattcct tagctttttc
     2701 tctgaatcct ttacttctga gtatagtctc attctcatac atattaattg aaccaataaa
     2761 agcaaggtgc ttattatccc ttctaaccag ttcctctgct gcagtttgtc ctcctttgta
     2821 atttgctgaa gtaacatagc atacattttc cgaaaaatgt ctatctatac ttacaaacgg
     2881 taaatcagat aaaatatatt tgtcaatatc agaatatgta ataccaataa ttccatccac
     2941 tttattttgt ttcaacattt cgatatattc gatttcattt tgtgaatcgc tatcagcgtt
     3001 acaaataaat aatttataat tatattttaa taactctttc tcaacatgat aggcaaactc
     3061 cgaaaaaaat ggatgccata tgctcggaat aatcaaagcg atagtttctg ttctattctt
     3121 tttcatacct cgagcataat tatcagggat atagtccaat gtttttatag ccctttgaac
     3181 tttccttaaa gttacttctt taatgccttt ttctttatta attacacgtg aaacagttcc
     3241 aacactaact cctgcttcta aagcaacatc tttcatggta attgattttc tttgttctac
     3301 catattatca cctcctttca atatatagta tcatgcaaat gctttttaag caactatttc
     3361 tcaatcattt ttggccagat catttatccc atcatgaata aaatcactcc aattagcttt
     3421 tgaaaatact tcaattttca tgtgtaaaca tctacataaa acaggaaaag ccttggtttt
     3481 atggcttttt tcgtatcttc tacaaaaaaa gcaagagttt tagagggcta taaatctaga
     3541 tgtacatttt gcttaaatga ttgaaggtct tttcttaaca aaaacacccc aaaaattaga
     3601 ttttttctgt ctaacttttg aggtacagtt caaacgcgaa atagcgtttt tttgttattt
     3661 ttggttactc atctaatcga ataaacatca tggcatttaa caaatatatg agtgagaccg
     3721 tgtttatatt atttgaatag atgagtctct tattttcaat aggaggaata ataaaattag
     3781 aaataatgat atcataagat gaatcttcta aagattcctt tgataattct aattcagtcc
     3841 aaacttccag ttcaaaatta ttgctacagt aataagaaag tgtctctgca acgaattttg
     3901 catgatactg atcaaaatta ctcataacca aaacctttag tttaggctga ttttgtagca
     3961 aattaatcac caaatgtttg gtatgagtga tgaaggtata agatagatga tttaccatca
     4021 ttgaactaga acaaacctca agagtctcta aatagtgaga aagctctttt tttatatctg
     4081 aaacaaattt tggaaaaata ttttgaaagt tcctgattgt attccctttt tgatcaaata
     4141 aaataaactc agtaaacaac tcttgacgat acagatgtgc ggtattatgc agatgccaaa
     4201 tcagattatc cttattctcc atttcaatct gatacttgac tgaaatctga tcaataaaat
     4261 cactcaatag atggtaagat ttttcaacat aactatcctt ttttacgcat ttcataaaga
     4321 gactttcatc tatgaaaaac attttttgaa agtaagacac aaataattgg caaacaactt
     4381 cttcatctaa agagatattg tattctgatt caaaactctg agcaacacct tctattcctt
     4441 ctgcctgcat taaaaaatcc aaactttggt cgttaaaaga atctttatct acttccataa
     4501 aatgaccaaa ctttattcta tataggttcg taactaggag caactttagc attctatgcg
     4561 ttgacaaatt cattggaaag cttgtttcct tataaaccaa ttctaacaat tgagatagtg
     4621 gctctgatga aaaattttca aatggccatt ctaggaaata atatttttct gaaaaatatt
     4681 gtgcaaaaaa gtaacgaatg tctctctcat ttccaatgat ttgaacaggg gtcagactga
     4741 cttcaaattg aaattgcctt ttaatcactt tattgatttg gctaataata cgatagagcg
     4801 aagatgaact gatataaaat tctttacaaa tactctcagc ttgacaacct tcattaaaga
     4861 agatgaattc taaaatcgaa aaatgagttg aatgtttaaa gaaatgatgg taaaccattt
     4921 caatatcact atcatcggta ttaataatgc gtataccatt agtagaagaa tgaaaaatca
     4981 agtcaggaaa agcagattta acatgggata gatcatcttt gactgcacgt tctgtacaat
     5041 ttaataactc tgctagttca gaacgatgaa accaacgttt atgttcaaat aataattcta
     5101 ataattctaa ttgcctatga ctttttttag ataataaatc tctcatgaat atctttctct
     5161 ctttataaat tatcggatta aacctcttgc aattatacca caaagaatag gtatagcatg
     5221 atataacgac ttttcctaaa atcttttatt tcgtataata acactacgga gacaatatat
     5281 aaacaatttt cttattttac cgtctattga gggcgtgaat acagaatcaa attcaagtct
     5341 aaagattata tttttaattt taaaaattat ataatagcaa caattaaaga atttgatttt
     5401 ttaaaattat ataataataa caatcgaaat aattgacttt tctatattaa agttatataa
     5461 tagtattaat caaagaaatt gattttttga tattaaaata aaaaaggagg gtaggcagtg
     5521 ttgtgatcaa ttattgctgg aggtcttatt ggtctcttgg caggtaaaat cactaaaaaa
     5581 gtagttctat gggaatcatc gcaaatgtat tcgctggttt agtcggggca tatgcaggac
     5641 aatctctttt aggtagttgg ggtccatcaa tcgctggaat ggctttgctc ccatctattg
     5701 taggtgcagc gattgtgatt actgtagtgt cattctttac aggtagaaag taaacttttc
     5761 gccagtaaag ttagcaaact atttttaaat caatgacggg aaaaatagtt taaatgttaa
     5821 atcgaaagga ttgtatatgt caaaagcaaa gaaaatatgt ttcattattt tctgtatttt
     5881 aatcttgaca attttccttc ctgttttgat agattatcat caagttagtg atctaggtat
     5941 tcatctactt agctggagac agaactccgt agttgaattc tatcttgcta gatatgtctt
     6001 ttgggggaca gtggttctat caactttagt tttattatcc attttagttg tgatgtttta
     6061 tcctaaacgt tacttggaaa tccaacttga aactaaaaac gatacattaa aattaaagaa
     6121 ttcggcaatc gaaggttttg ttagaagttt ggtgagtgat catagattga tcaagaaccc
     6181 aactgttcat gtaaatttac gaaaaaataa atgtttcgtt catgtagaag gtaaaattct
     6241 tccttcagac aacatcgctg acagatgcca aataattcaa aatgaaataa ctaatggatt
     6301 gaagcagttt tttggtattg agcgtcaagt aaaacttgaa gttgcagtaa aaaattacca
     6361 accaaaacct caaaacaaaa agactgttag tcgtgtgaag taaggaagta aaaaatggaa
     6421 tggcttaaac aatatcgata tccaattatc gctggtctca taggcgtatt tctggcttgt
     6481 ttgattgtct cctttggctt cttcaaaaca atatttgtat tgattttagg agcactggga
     6541 gttgcagctg gattatatat cgaaaaaaac tatatagata aataaaaaaa taaaaattac
     6601 taatttaatt aaaggagttt catatgtcaa acgaaaaaaa cacaaatact aacgtagaaa
     6661 agaaagatgc tactgttgta gctcacgaaa tcaaagggga acttacttac gaagataaag
     6721 ttatccaaaa aatcattggt ctttcactag aaaacgtttc aggtcttttg ggaatcgatg
     6781 gtggtttctt ctcaaatctt aaagaaaaaa tcgttaacag cgatgacgta acaagtggtg
     6841 ttaacgtaga agttggtaaa acacaagttg cagttgactt aaacgttatt gttgagtacc
     6901 aaaaaaatgt tccagcttta tattcagaaa tcagagaaat cgtatcttca gaagttgcta
     6961 aaatgactga cttggaaatt gttgaaatca acgtaaacgt tgtcgacatc aaaactaaag
     7021 aacagcatga agcagactca gtaagccttc aagatcgcgt atctgacgtt gctgaatcaa
     7081 caggagaatt cacttcagaa caattcgaaa aagctaaatc tggtcttgga tctggtttct
     7141 caactgttca agaaaaagtt agcgaaggtg tagaagctgt taaaggtgca gcaaatggtg
     7201 tagtatctca cgaaaacact cgtgtaaact aagataaaat aaatataaca ggagaaatta
     7261 tcatgtcagt agaagaaaaa ttaaatcaag ctaaaggttc tattaaagaa ggtgttggga
     7321 aagccatcgg tgatgaaaaa atggaaaaag aaggagcagc tgaaaaagtt gtttctaaag
     7381 taaaagaagt tgccgaagac gctaaagacg ctgtagaagg tgctgtagaa ggtgttaaaa
     7441 acatgttgag tggcgatgat aaataaggtt aaaagttact ttatcttttt ggtaacatta
     7501 gtcaaaagag tctgagtcaa gatgattctc agaaaacaaa aagctagaga ttcccaattg
     7561 cggaactcta gctttttaat tttgcctctt tctcttatta tatttcagca ggttgttggc
     7621 catgagtatg aatcccatgt caattctcac ttgacgctta cctctcagat gacatctctt
     7681 ataacccaaa caaaccttta tctgcccaaa gacagatttc atatcaatct tacgtttagc
     7741 gaaaatttgt ctacccttgg aagataaaag tgcctgatat tctttagttt ttaaacactg
     7801 gtaacgttca ttcatataca gtcccttttg aggggctgat tcaggttcat aatcgcagtc
     7861 aacattgatt tcaaggctgt ttgctttcta tctccccttt ttcatgatat attttcgtac
     7921 aggttcttca atagtttcta tagtaaaatg aaccaaaaat agtacacgtt gcggtataat
     7981 gttcttgtgg catattcatt agattttcgt aaacagttct ctcctatttg tgagcgaaca
     8041 agtatagtca attgattgtc agtttgaaga ccaagagtcg taaggcaaag gatatggcag
     8101 aatccatcca agggtggctg gcacaatttc tagtgaacct ctttaaatct attacgtttg
     8161 actgtggaaa agagttttca aaatggaaag atatttccaa tcatcacgat agtgagagct
     8221 tttttgcgaa tctaggatgt tcaagacagc ggcgtctcaa cgaacattca aatagacttt
     8281 taaggtgtca tgacttgcca aagcagacag atttcaacga agtcagtcaa gaattttagg
     8341 ctggacaaaa actcaatttc aggagaaaat gaaataaata ttcccacaat aaaacgcata
     8401 gtatcaaagt ttttccaaca cctgatatta tgcatttttt aattttaaag actttttccc
     8461 agcctcaaga aatcacatcc cacctaaatc ctttggatac caaatacctc atcaggtatt
     8521 ttctgagttg gtaagaatgt ctagcttaat ttgacaaatg gagggcgtta aatccagttt
     8581 ttacaggaag tctatttaaa tattttcaca ctgaccttac aaaatatgaa ataaattata
     8641 taaagtcatt cccatgacaa agaataacat ccctttaaaa cagtatctta cccaattttc
     8701 aggtaagact tttgatacaa ccgtccccaa tacccctccg catatagaag caagaaaaat
     8761 aactggaaca ggtgctaaat gatactgatt taaacctgta accacaacaa ttgtagccaa
     8821 atgagacagc tgggaaaaga aaataattgc aagagaatac atcgttgctt cttttatcga
     8881 aatagaaaaa aacaccatca ataaagatac attgagcgga ccaccaccaa tccctaaaaa
     8941 actagaaatt aagcccaata gaagaccaca aatcatatag aatcctatct tatcaaattg
     9001 ataagttttt ttaaaatctg ttaaaacaaa tgatacaagt agcatcacaa atagtaaaat
     9061 catttgaaca atggatacta gccgtactga taactgagat aacaaaactt gaaaaataag
     9121 atgacctaga aatcctccta aaacagaaga aaaggatacc gtaaaaatca atctccattt
     9181 tatctcttta ctttgtgaaa atcttttgat tgttgaaata atcgccatta taaaaacaga
     9241 gaaactagaa taaaaagcaa tatcactgac cgaatggtat ccaaaactat ccataagtgg
     9301 cttaattata attccaccac ccatgcctga tatagaaccc aatccactag ctattataat
     9361 gattagaaaa taaataatct caaccacttt ttaagtccat cctattcttt caaacatcta
     9421 aaacctagat ggctactagt ggaagtagag atacatccat ttctagcagc tactcggtat
     9481 cgattacaat aagaacaatg acataaaaag gaacctcctc tgatagcata ctcctcatct
     9541 tgtatcccat attttggcaa ctcatagtca tcttcattaa aactagctaa taaggtatat
     9601 ctcggattgc gacaccattc ccaaacattc ccaatcattt gatatagacc aaaatcatta
     9661 ggtaaaaatt catagacagg agccgttcct ataaatctat ctaaggcagt attttcataa
     9721 ggaaatcttc cttgccaagt attggcatga taatatccac cttctaaaag agtatctccc
     9781 caaggatatt cagattgtct tcctcctcta gcagcatatt cccactgtgc ttcagtaggt
     9841 aaagacattc cgctccaatt acagaaagcc aatgcatctt ctaaagcaac atgaactact
     9901 ggatggtctt ctaaacccac tagattactg ttctcaccgt agggatgttt ccagcaagcg
     9961 ttcggaactt gtaaccacca cggagcccca gcaggatgag gatatccctc cctttctgcc
    10021 tctggaacga acaatataaa aacaaaagac cactcttgtc gctcagctag tgttttatag
    10081 cctgtttctt tcacaaattg agcaaattct tgattcgtaa ctggagtatc cgcaatggaa
    10141 aaatccttta cactaacagc gacttgagga ccttcaaaat catctaaaaa gccctcttca
    10201 gaatttgttc ccatcataaa tgtcccaccc ttgatttttt tcattttcat gattgactat
    10261 cccccgtttt cgttagagtt ggcgttattt tagaaagttc aacaggaact aactcttcat
    10321 ccacaacaaa accttcttct ctatatctaa gaaagtctac taattttttc ttcatctgac
    10381 gaacaatagg ttggtatttt tcgcttggat acaaatcatt catttcatgc ggatcttttt
    10441 tcatatcaaa taactgataa tgatttaaaa caggaaacca gataaatttc cactggtctg
    10501 tcaagatata ttgactagaa tcttttccta aagcatgttc accatgaaat tctgttcgcc
    10561 acccctcgta ctgtccaaat aataaattct taacactccg tccatctagt tcatctgtag
    10621 tagttcctcc tgccaaatcc acgagtgaag gaaaaatatc ttgaattttc actaattgct
    10681 tgattgttcc cctattacca gctatcaatc cagccggatc gtaaataaac gaaggaatgt
    10741 ggatacttcc ctgataagga tatccctttc taaacagata atgttcacca agctgatctc
    10801 catgatccga aacaaaccag ataatcgtat ctttatcatg acgaaattct tttagggaag
    10861 tcaaaaagcg actaatttga tggtctatat gagtaatcaa tccaaaataa gcagcaacca
    10921 ttcttctttg atcatcttcc tttaatttcc ctcttaaagc ataaatagac ggaatttgct
    10981 tttctaatac ttcccaattc ccgatatgca aatcgagaaa ttgaggcaag cgttccatat
    11041 acatatcaaa atagtatttt gggggattta atggagcatg tggtttttca aaagacattt
    11101 tgagaaaaaa aggaaccgtt ggatctcttc tttgtaaaaa tgaaatggac tcactcacaa
    11161 cccagtttgt tggatgtaac ttctcatctt tatcccaagg tctagcttcc caagaattac
    11221 aatccattcc gtcatcaatc aaatcaacat cataaccaac tttacccttt aaaaaggcta
    11281 gatagtcact aacataatca aattgacttc cataagcctt atcatacttt ctatcaacat
    11341 gtagataccc atcgtgaagt aagacatgat caaacccaag tctctgtctg gaaggaaaaa
    11401 catgcatctt accaatacac tctgtttgat aacccatatc tttaaagact tttggaagag
    11461 tattagtaaa attccaaggc acctcatctt gataaccaac acgtccactt ttatcttggt
    11521 ctaagccagt caataaagct gccctagcag gaacgcaaga aggaactgga gaataggcat
    11581 tttcaaaatt ataacctaca ctagccatca tatctaatgt tggagtgcta actagcttat
    11641 ccttactatt caaggataag gcgtctgctc tcatttgatc tacaacaatc aaaataatat
    11701 ttggctgttt tgtctgaacc ataaaatctc ctttctaata tggcaaaaga ggcacaagaa
    11761 gatatctacc tttactgcac ccctttctat atcaatctct ctatataaag caataacatt
    11821 cttgttatgt tttatagaac aatgaactaa aatatgacta aatcgattag gaaattcaaa
    11881 tcattttcta gtactgtttt agaagttaca gtgtactatt ccaacttcaa caaactataa
    11941 accttggtct aataacaatt ttagtggaga taagaaatcc tacacctaac tcatcttaca
    12001 cgtaatctat ttctatttta tcacaaaaaa cgcaagtaag accattaact caattcagtt
    12061 ttatctgcca ttttcacaaa tgggaaataa gtcaagacac taataatcaa acaaacaact
    12121 gataagatga tggcacgcca atcaaatgct gtagagaaga aaccatataa aattggaggc
    12181 attacccaag taacattttg tgtaacaggt gaaacaagac cccagcttgt tgcccagtaa
    12241 gctaccgttg ccatgaaaac cgggctaagt acaaatggta taaatagcaa aggattcaag
    12301 acaactggta aaccataatt gaccggctca ccaatattaa acagaactgg tgctagacca
    12361 agtttagcaa cttttcgata atgactgttt cttgaaaaaa ttaaaatagc aagtaccaat
    12421 cctaatcctc caaaccagac aaacgcccca aaagacccac ttgtccatat ataaggaatc
    12481 ggttcacctt tttggaaagc atccagattc gctaacatag caactccaaa cagcccttcc
    12541 atgatgggag ccaatacatt tcctccatgg agaccaaaaa accagaataa cttatttaaa
    12601 aagatcatca gaataactgc aaagaaactt tgagacaaac ctagtaatgg cgtttgtaac
    12661 accttgtaaa cccaatcaat caataagtca ttgctaagta aatggaaaac ataagtcaag
    12721 atggctacta tatacatcgc cataaatcct ggaatgatag aagtgaacgg cttagcaatc
    12781 gcagggggaa ctgaatctgg taacttgatt acccagttct ttttcattac tttacagaaa
    12841 ataatagagg ctaaaaatcc aatcatcatg gctgtaaagt agcctctggc attaatatgg
    12901 tttcctggaa tcacattccc aatagttacc atcagatttt taccatcaaa tgctagatta
    12961 tcaattcctt gtaagatctg atctaatttc acatctccta catttgccaa agggaaactc
    13021 tttgtaactg tacttccaat cgaaatgaca aacgaagcaa gtgataccaa accagcagaa
    13081 actgtatcaa ccttgtaaat cttagcgata ttcactccca agcaatagat gaacaacaaa
    13141 gaaacaattg gtatacttcc cttgaatacc aaattattga tgtcaacaag ccactgaaag
    13201 gttttcgtaa tactttctag gtgaaattgt tgtggtaaat ccactagaaa agcatttaat
    13261 aacaaagcaa tggaacctgt cataataaca ggcatagtcc ccacaaatga atcacgtaaa
    13321 gcaactaaaa acttctgatt cccaactttc attgcaattg gagaaagttt ttcttgcatt
    13381 ttatccaaca ttgtattcat actaaactcc taattttttt caaatcgttc gtatacttct
    13441 accacttctt tcgccaagtc aacaaaagtc agactcgtca ttaaatgatc ttgcgcgtgt
    13501 accatcaaga ggctaattga tgtttcttcc ccctgtgcct ctcttgtcaa catttctgtt
    13561 tgagccttat gcgcctgtaa taaggcagca ttcgcatcag ctaatcttcg attggcttta
    13621 gagaaatccc ctttttttgc tgcctgaata gcctccatag cattactttt ggcttcccca
    13681 ccatacataa ttagccccat tacagattct aaattacttt catccataac attctcctca
    13741 atcttagtct aataaacttt cagctaaatc taaaacttta gaaccattca tcattccgta
    13801 atctgtcatc ggaataaccg ccacaggaat ctgtctatct tttagttttt cttgaaagtc
    13861 ccctagtaaa tagcgaactt gggggcctaa aagcaacaca tttacttctt ttgttgctac
    13921 aatttcttct gcttcaggag ctggaactgc aaaaatttct gcatccaacc ccttatcttc
    13981 tgctgccttt tgcatctttg tcactagcag acttgtactc atacctgctg cacacgctaa
    14041 cataattgtt actttagcca tagcttactc cttttatttt attgtcaatg ttactgtttt
    14101 tcgatcaact ttagactcat aatctaaatg tttgggacga ctagtataat gcaaattata
    14161 aactcctgga ggcatttgtg aaatcttttc tttttcagtt ttattgcgaa ttaataaatc
    14221 taccgaagta ttccctccaa agttattaaa cataggttca ttttcaatag aataatctaa
    14281 ctcatatcca ctattagttg taattccttt taataaatca ggaacatctc ctctgtttat
    14341 tactatatcc ttagcgccat ttattttggg agattgacta taatactctt cagcttgatg
    14401 ttgttgtaaa tcatttctag agtaagaaac ataatcaact acaaattcag tccctgataa
    14461 attattgtcc actaccccag gccaacttcc tcccatcgct aaatttaact gaacatactg
    14521 aggtctatta aaaatctttt tcgctatatt atctgatcca taatatactt ttctaacaat
    14581 atgattgtca accatccata caatataatc tttataccaa tcaattgaaa aagtatgata
    14641 cgaatcatta aagtttccac tcgataattt aaaggctgta ccacgtcctg caaattttcc
    14701 atcatcatta tccgactgtc cataatgaag cgtttgataa actgtcttat tcccacttcc
    14761 atttgaattt cgttcaccaa ctaattccat tatatctatc tcacctgttg acggccatcc
    14821 tcgtccctga acaggattaa tcttcccatc aagtgtaaaa tccgatccaa gagtccagaa
    14881 agcaggaaaa actccttgac ctttcggtaa ttttgcacgc atctctaatt taccataaag
    14941 aaattctact ttcccatgtg ttctaacact tcctgaatta tatacaacct ttctgtgatt
    15001 gtttcttggg ttaaaatact gatcttcctt agagcgattc gtagctctaa gaactaaatt
    15061 tcccgaacgt agaaaaacat tctcatcact tcttacataa tgttgctgtt cccaaccacg
    15121 aattgatcct aattcatatc cccaatattt tttatttaat tgttcgccat caaaatcatc
    15181 tctccaaatt ttcttatatg aatttccttt agacagttga tacatctcta cattatcaat
    15241 aaaaatatta gatttttttg tagtatcgtc ttctgaccat ttcactaatt gaatcaaaac
    15301 tttatcgtgt ttaccggaat tgaaagaaaa catgtatttt ttccattcgg ttgtattaac
    15361 tgtttgatca acagcttctc caatgttatt ttgaacaatc tctccttgct tattattatc
    15421 aaaccatctt gcggtaaaat atccctctgc tccactaata tctactttgg caaaagcaga
    15481 tactaaataa tcttcattag gttctatatc aataacttgt ccaatatatc catctgctct
    15541 attatcatta attgcagtag aaggaatcat acctgagtaa tgtccgttac tataactctc
    15601 atttgaatta attattcccc tatttctaga gttccaaaac agctctcctt gctcaaaatt
    15661 tgaatttttt attaaatttt cattagcaaa aactttcaca tgaataaata ttaataaaaa
    15721 taatataaat aaacttgaaa ttaatttctt attcttcatt ttatcaccta tttactgacc
    15781 tagccaagcg agatactgta tgtctcactc ctctaattgc cttgctcaat gcataaatat
    15841 tatcgactgt tgccagtccc ccatatcctg cgtcacctat atgttgaata tcaactccac
    15901 aaattttatt tctaagtgca atttccttga tagtatctgt atcagatgtt tcttggctag
    15961 taccaatagc actcagtact agcccaccct tactatgaac gagatcaacg acttcacgca
    16021 actcttggtc atgaaaggct ggaacggttc caactgctgg aacaagtatc acatccgcac
    16081 ctgcttccaa caattgctct gcgacagaaa gctctgccac aggctcattc actcctgccc
    16141 cgtgcatctt acctgcaata atcaaaccag aaaagttttc cttagcagtt tgaacagcct
    16201 taatgatttc tcgattgcta actcctgttc caggatttcc agtcaaacag acaaagtcaa
    16261 aacctaactc ctctattcga ttcaatgttt caacactagc aacacgacct gcaacaattt
    16321 cctgtgtttc ctctagcatc tttgcagatg ggtcaatcgg ttccaaattt acaccaattg
    16381 gacaagcaac aagctggtgt aagcgatgaa taacatcatc acctgaacta tccaaagcat
    16441 aaattttagg ctcaaaaaca tcaacacaat tcaataaaat catatcagct ccaaaagctc
    16501 tagcaatttc agaattagtt atatccccaa caaatgtctc acgagtaact acattttcag
    16561 atagaacaac tctaccttca cttgctaaaa tactttgttt taattcttca gcattcatct
    16621 gtaatatctc agatggattt gcactaatta aacgtttcat tctcaatcct ccaataactt
    16681 aaaccgtttt tcaatagcta ttacaaatgg taaataaagt aagacatcca aaacaatcaa
    16741 tacaatttgt aataatgaac cagaaatact tcctgtagca agtaaaccac ttataacagg
    16801 tggcatagtc caacttggat ctgtataagt tagcggaacc aaacctgatg ccattgctcc
    16861 ccacgctact agtaagttaa acattggagc taagataaat ggaactagta acaaaatgtt
    16921 caaaacaata ggaacgccaa acattgctgg ttcatttata ttaaataatc caggtataac
    16981 agttataggt gccaaagttt ttagttgttt actagctttc ttcttatgtg ctaaatatcc
    17041 taacgcaaga actaaaccta tggttgcacc accgccacct atgaatacaa aattatccat
    17101 aaatacgcta gtaaaaatat ttggaagagt ttctccagtt tgataagcta ctttatttgc
    17161 atctagatta gctaaccata acggtttcat aactgcatta acaacatttc ctccgtgtaa
    17221 tcctacaaac caaaaactac tattaaggaa aattaagata agaagaccaa taacattatt
    17281 tcctaaaagt ccaagtggac ctcccaaagc tccttgagca atttcatgaa gattaggtaa
    17341 acttaattta tctaaagttg cataaacaat caaccaacca acaatagtca ctgcaccagg
    17401 aataatggca ctaaagcttt tagatactgc tggtggaaca ccatccggca tttttatctg
    17461 tatattatga tttataaacc attggtagat atagccatta atcaatccta aaatcatagc
    17521 aacaaataaa ccttttgatg ccatgaaagc ggtaggcatt cctgctccag cctctcctgt
    17581 aatgaaaggc gtaactgtaa taaaagatga taatgacaca ataccagcag gaataccatc
    17641 aactttgtat tgtctagcca taaagtaagc gataccaaaa ctagctacaa gaccaagtaa
    17701 tccaaaacta ctatcaacac ccttccataa atagtcagca acaccaatat cacctagata
    17761 tttttcccat cctggaatag gaaaacttgc aataaccatt agtaatgaac ctatcaacaa
    17821 taaaggtata gttagagtaa taccgtctcg aatagaaacc aacgctttat tattacccaa
    17881 tctagccgct actggaagta acttttcttg taataatttt tccataacct tttcctctta
    17941 aatatatttt attatcaaaa gttatcaatt atctttattt tttgacgtca agttattatt
    18001 tgattatctt ttgttattta tattttacaa ctataagaaa gccttgtcaa ggatttgtgt
    18061 aaatatttga ttatttttta ttatcaatat ataataaaaa gagaccagta agcaatgaaa
    18121 agcttaaaaa gattaacatc tacatttatc catagcaaaa aatcatagga ttttaagaat
    18181 ctgacaacta ggaagaaaac taatatgacc ttatctaaga aacaattaca actaagagct
    18241 aaaatactgg aaacagttta cacattaggt cccatttcac gaattgaaat cgctactaaa
    18301 acaggaataa cacctgcaac aactagcagt atcacaaatg atctgattaa agaaaatatt
    18361 ctcttagaac ttggtgaaga cgaacacgat acaagcgtag ggagaaaaaa aatcctgcta
    18421 gacattcaag ctaaacgatt ttactacatt ggttgtgaac tatctgaaaa acatttcact
    18481 tttgctttag gagataatct aggaaatatc ttaaaggaag agaaagaaat tgttactaaa
    18541 cagttaatcc aagaaaaggg aaatcaactc attaaccaga cactaaagca attcttaaat
    18601 aactgctctg attatgaaat agaagcaatt ggaatcgcgc tacctggtcg ctatttagat
    18661 gattataaaa taacaacaaa caatccttta tggcaacata tcgacttaga aatgattcaa
    18721 tcccactttg ataagccttt gtttttctct aacaatgtta actgtatggc tataggtaaa
    18781 cgcctattta gtcgccaaca gaatgaccct aattttgctt attttcattt tgctagaggt
    18841 atgcactgtt cttatatcta cgacggaaac atttatggga aaggaaatct aatgattgga
    18901 gaaatagggc atacagttgt ttcatctgag ggagaagaat gtagctgcgg gcgcaaggga
    18961 tgcttacaaa cttttgctgg agaatcttgg ttaatcaaaa aatcaaaaat tctatatcat
    19021 caatctccct attctctact tcctagttta gtcaaaaatg ccgatgatat tgatatccaa
    19081 gttattttaa ccgcttatca attaggtgac actggaataa tcacacttat ccatcaagcc
    19141 ttactctatc ttagtcaaac cattttaaat atcagtatga tgattgactc tcaaaaaatc
    19201 tacctacata gtcctttact aacaaatcaa cacatcatcc aaaaactata tagtgaaatg
    19261 aactacaaac ccaaactgct ctataatcgc ctacctgaag tcattattga accttacaat
    19321 gattttacag ccgcacactc agctattgca ctttgtttgt atcatacaat tctacattct
    19381 taattttcta ttacatttaa taaataggct aaaaagaggg agtatatcat aaaaagcgaa
    19441 taaacctgtt ttctgaaaat cagaattctg ttttgttcgc tttctttata tttggaatta
    19501 tactcctatc tccccttttt cataatgtat agtgaaatga aataataaca ggacgaatcg
    19561 atcgggacag tcaaatcgat ttctaacaat gttttagaaa tagaggtgta ctattctagt
    19621 ttcaatccac tatattttcg tacaggtgct tcaaccattt gaacgatttc aaatccttct
    19681 ttttggtaaa gattctgagc tctttgattt gcctcgaaga catttagaga aatactatct
    19741 atatcttcat tttcaaaggc caaactaaca aatttcctta aagcctggct acctaagtct
    19801 tgctcctgtt tctgggggtt gataaaaaat ctcccgatat gaagattgct gtcttctagc
    19861 ctgattttct ggataagtcc cacaaactct tgttcatcaa agattgaaaa gactccttcc
    19921 aaggcttgaa ggggcagtag aaaaggaatc cttggtccca tccattgttc ttgaaaggat
    19981 ttgcctaggg agttggacca ctggcataca aattgagcgt tttctatact caccttttct
    20041 tcaaaacgaa ttgtcatctt ttcctcacca tcttatctat gtttctccat tatactattt
    20101 ctcccatttt ttacgaatag ataagtatga ttgattttta tttttttctc gtcgggagca
    20161 ttctcgcttc ctttcttggt ttggtcattg accgttttcc agagcaatcc attatcagtt
    20221 cagccagtca ctgcgattcc tgtcagactc ccttgcgtcc cttagatttg attccgattc
    20281 tctcacaggt cttcaatcgc tttcgctgtc gctactgcaa agttcgctat cctgtctggt
    20341 atgccctctt tgaactaggc ttaggactcc tctttctgct ttactcttgg gaattgcttt
    20401 ccttggggca agtcgtccta atcaccgctg gtttgacctt gggtatatac gactttcacc
    20461 atcaggaata tcccttactg gtctggatga ctttccacct aatcctaata gcttcctctg
    20521 gctggaatct ggtcatggtc tccttcctca tacttggaat tttggctcat tttattgata
    20581 tccgcatggg tgcaggggat ttcctctttt tagcttcttg tgctctcgtc tttagcgtaa
    20641 cggagttact gatcttgatt cagttcgctt ctgcgacggg tatcctggcc tttctcctgc
    20701 aaaagaaaaa ggaaagactt cctttcgtgc ctttcctctt acttgctact tgtgtgatta
    20761 tttttggtaa gctactactt gtttgataaa ttccaatttc tgccatatgt actccatgaa
    20821 attatttcac agttaaatta taaattattt cttttgtaca aagggatgat gttatcaaat
    20881 cgatctgttc ttctatcttc ttgatactga tcaaaaaatt tcatttcgac tgaaaatatt
    20941 tcgcttataa actgtaaacg aatactttgt ttagacatta tagtcgctag actgactaga
    21001 tgattactca aaacgacgtc cagaatactc tttactttgc ttggtttttt aacaaaaatt
    21061 tgatcatcca aaggttcaat cattttgtaa cctttttgcg caatttgacg ataaaagtaa
    21121 gaatgttgct ttggagtcaa taatcctaac ttaaaagctc gatactctaa agcctgtatc
    21181 gaaacattca aatccgactt caataaaata taactatcag gattgctgac acgcttgcca
    21241 accctctctt caaatttgac taaaaactct tcttttggca ataaaaaaca tgatgcaaaa
    21301 taatttgctt cttgctccaa acgatcgcca tcttcattca tatctttata tttatgtaaa
    21361 agaatatgtc ctagctcatg agctaaatca aaatttcgac gtacagatga tttattcgtt
    21421 cccaacacaa tataaggtct tcccaatttt gaccatgcgc tataagcatc agcttggcca
    21481 ttaattaatc gttccacgat atagatgcct gaacgttcta atttataaag caaatcatga
    21541 ttatcttttg aaatacctaa tttttccctg gcataaagag ccaattcctc aatggattct
    21601 cccttatgat aagattcact cactacatta cttaggtcat gaattgtaat attaggtata
    21661 attacaaaac tttcaaaata atcaatcaaa ctatctacct tatgtaaata catagtttga
    21721 atatctattg ttttccgggt tgctaggtct gcatttctaa aggcaattac agaagaatca
    21781 aatcgaatgc tctcttcttc ctgttcaaaa taagttaaat caacatgaaa ttggttggcc
    21841 aaatgcattt tggttgataa tttaggtttc gtttcgttgg actcaaactg ccaaatggct
    21901 tgttccgtta aattaattct ctgagctaat tctgctctac ttaaaccatt taacagccgt
    21961 aattctttca atacccgacc attaaacatt tacatactcc ttactacttt tgaccttctt
    22021 gtttttctat tcttggaata atttcaaaat cttctgtttc cgataattct gaaaaattag
    22081 gaatatcttg atatttagct tcttcgaaat ggtacgaact tgattgaata tactcagaca
    22141 aatcttgaat caagtgtaac tgaccagttc gtgcatcagg cataacaaca tctacagata
    22201 taatattgtt ttctgagtcc gcctcataag ttaaaatcat aaatttttcg atattcgaat
    22261 ttttagtagc ttgttcaatt tcttgaatca tttcatcaga aactaactcc atctgaattg
    22321 gaaaggaatg actatcttca tcatttttgt aggaagaatg ttgattaaga taaagtgtat
    22381 tcatctgagc atattcaaat aagtagccac tcttattttt ttgtaccaaa ggaaattggt
    22441 tcgtaagtcg cttcttaccc tttataatta acaatacttt cccatatttt tctgtgtttg
    22501 tttcaaattc taaatatccc caagtctgtc ctgctaattg taatttatac tcaaacaaat
    22561 ctgctgatgc aaatgcagta tcaatatgat taggtcgcgt ccatgcataa ccattcgaca
    22621 ctatcattgt ctctcttttt tctagacgtt catctacata atctttttgc cctttcatca
    22681 aagtatctac aattttttgt gcctcaagcg aatcaaagag atcctgattc aacataattc
    22741 ttcctcctcc aaatactttt taatgaatta tatcattttc ttaaagaaat tactacaata
    22801 attagctttt tcttaaagtt ctgtgtcaga gtaatttaga aaattatatc ttctatagta
    22861 aaatcaatta aaaactgaac aaatttattg ggaaattcaa atcactttct aaaaatattt
    22921 taggaaccgt agtgtaatat tccagattca atttactata aaactagcct ttctcctgca
    22981 aaagaaaaag gaaagacttc ctttcgtgcc tttcctctta cttgctactt gtttaattat
    23041 ttttggtaag ctactgcttg tttgataaag tcctgaatcg gctctccttg gtggagagct
    23101 tttactattt tcgaaccgac gataacacca tctgacaccg cattgaagcg ttccagatcg
    23161 gcttgactag atacaccaaa acctgtcaag actgggatgt cggccacttg atgaagttgc
    23221 gccaagtgct tgtccaaatc tgcacggtaa ttgcctgatt tccctgttac cccattgatg
    23281 gcaacggcat agacgaatcc ctccgcccct tcaatcaact ctttctggcg ctcaattcct
    23341 gtggtcaagc ttactaaagg aatcaaggcg atatctgtat ctgccaaaaa tggttctaca
    23401 aagttggcat gttcatgagg caggtctggg ataatcaagc ccttcacagc tgtatcagcc
    23461 agatctttga caaagttctc cacaccgtac tgaaagaggg ggttgaagta ggtcatgatg
    23521 accagtggaa tctctgtttc aatggttttc aaggtttcaa ctaaagcctg ggtagaggtc
    23581 ccgtgggcta aactgcgcaa gccagcttct tcgataacag gtccatctgc aacagggtct
    23641 gaaaagggaa tacccacttc aattgcagag acacccaaat cttctaaaaa gtgaattgtt
    23701 tcagcaagac catccaaacc tttttcgtgg tcaccagcca tgatataggg aacaaaaatt
    23761 ccttttccag ctgctttaat agcatttaat ttttttgtta gtgtcttagg catgagcttc
    23821 tcccttcttt gctgcatctg cttccaagcg gtcttttact tgaaccacat ccttgtcccc
    23881 acgacctgat aggcatacaa tcatagactt ttctggtcca agttctttgg ccaatttcac
    23941 cgcaaaggcg atagcatggc tagattccaa agctgggata atcccttcca cacgagacaa
    24001 gagttggaat ccttccaagg cttcttcgtc tgtcacaggg acatagctgg cacgtttaat
    24061 atcgtggtag tgagaatgct ctggaccgat accaggatag tccaaacctg ctgagataga
    24121 gaaggcttca agaatttgac catgggcatc ttggagcaca tccatgaggg aaccgtgaag
    24181 gacacctgga cgacccttgg tcaaggtagc tgcgtggtgc tccgtatcca caccaaatcc
    24241 agccgcttca gctccataca tggctactga ctcatcttct acaaagggat ggaagagacc
    24301 gatggcattc gacccaccac caacacaggc tactagggca tctggcagat tttgtcctgt
    24361 caagtcacgg tactgttgtt tagcctctcg accaatgaca ctttggaagt cacgaacaat
    24421 ttctggaaat ggatgaggcc ccaaggcaga accaaggata tagtgggtat catctatatt
    24481 agccacccat gaacgaaggg ctgcattgac cgcatccttg agcacgcgcg aaccatctgt
    24541 cacggcctcg accttagctc ccaaaagctc catacggaag acattgaggg cttggcgttt
    24601 gacatcttcc tcacccatgt agatggtaca ttccatgtta aagagggccg cagcagttgc
    24661 agttgccaca ccgtgctgac cagcaccagt ttctgcgata attttctttt tacccatgcg
    24721 tttggcaagc caaacttgtc ccaaggcatt gttaatcttg tgggctcctg tatggttaag
    24781 gtcttcccgt ttgagataaa tcttggctcc gccgatatgc tgggtcaagt tttttgcgta
    24841 ataaagagga gtttcacgtc ctacgtactg gcgcaaaagc tggtttaatt cctcttggaa
    24901 acttgggtct gcctgacttt cacggtaggc cttctccaac tccaaaactg ctgtcatcaa
    24961 tgtttctggg acaaaacgtc cgccgaattt tccgtaaaat ccatctttat ttggttcctg
    25021 atatgccatg ctttaccctc tctataaatc ttctaatctt ttcatgatct ttttgtccat
    25081 ctgtctccac tccgctcgat acatctactg catagggagt aaaatgttga attgctttta
    25141 ctacattatc ttcattaagg ccacctgcga taaagaaggg ctgtgctagt ccagtcgtat
    25201 ccagttgacc ccaatcaaag gactgaccac ttcctgccac aggggcatca aagagtagat
    25261 aatctgcctg agaattgggg acatgcccat ttccatctac ctgcacagcc tgaatactgg
    25321 cacaaggcaa attctcaaat aaatcagctg ccacctgacc gtgaacttga accaagtcca
    25381 agccaacttt gtcaatcgct tccagcagtt ctacccgact tggtgaaaca aatactccaa
    25441 cctttttcac atctgcagga ataagctttg ccaactcagc tgcctcttct aaagtcacct
    25501 gtcttttact aggtgcaaag acaaaaccga tatagtcggc tcctgctgaa acggctgttt
    25561 ccaccgcttc tttggtcgat agtccacaaa ttttaacctt tgtcaatctg caactccttg
    25621 attctctggg ccacattttc tgcctgcata agagctgtcc ctaccaaaat tccgttaaag
    25681 tatggggcta gtcgttccgc atcctgccct gtgaaaatgg cagattcaga aatgtaatag
    25741 cgaccttcct caaagtaagg ggctaaatct acactggtct gcaagtcgac ctcaaaggta
    25801 gtcaagttgc ggttgttgac cccgataatc tcagcaccaa gtctgtgggc tacctctagt
    25861 tcagctagat tgtgagtctc cactaagact tccagaccaa gctctgtcgc gtagtcatac
    25921 agttccttga ggcgttcttc ggacaaggct gccacaataa gcaagataac tgtcgcacct
    25981 gtattgcgag cgcggatgat ttgcttttca tctatgataa agtctttgtt gagcgtcgga
    26041 atctctacct gactggaaat ttcccgtaga taatccaaat gccctttaaa gaaaacctca
    26101 tctgtcaaca ccgaaatcat cactgctccg ttttcttcat aagtctgggc ctgttgcaca
    26161 atatccacat cgagattgat atctcccaaa ctagggctag ctttcttgac ctcagcgatt
    26221 acctgcaagc agtcctgatg attcttcaaa aattctgcca agcgataggt ctggcgcaga
    26281 ggctggattt gctccagctt catctgctcc acctcacgcg ccttctgctc taagattcgt
    26341 gctaaaaatt cctgactcat ttttggtact cctgtaacag tctgagtttt tcaagggcct
    26401 tgcctctagc aatcacttga cgggccaagg caactccttc cttgatgcta tcaatcttac
    26461 cattagcata gaaaccaaga ccagcattca agactgtcgt ttccaagaat ggacttgctt
    26521 cgtttttcag aacgctaagc aaaatttctg cattttcctg agcattccca ccacgaatat
    26581 cttccatagc atagtcttcc attcccaaat cctctggagt aaagcttgac aagctgattt
    26641 cgccattttc aagaagtgca atcttggttg ttccgttcaa gccagcttca tccaaccctt
    26701 ctggtccagc aaccacgatg gcacgtttgc gacccatatt tttcaaaacc tgagctgtac
    26761 tttctaggag ttctggacga ctaattccaa gaagctgtgt ttctaaagcc attggatgaa
    26821 tcagtggacc agtcaagttc ataatcgttg gaattcccaa ttccaaacga gctggcatga
    26881 tgtatttcat agctgggtgc atatttttag cgaagagaaa gacgattcca gttttatcaa
    26941 agaccttacc tagttcagct ggtttgaggt caagattgat tcccaaggct tcgaggacat
    27001 ctgcggaacc agatttagaa gaaatcgagc ggttaccatg cttggccatg tgaataccgc
    27061 caccagccaa gacaaaggct gcagttgtgg aaatattaaa actgaaagac ttgtccccac
    27121 ctgtaccaca gttgtccata gcatcatgaa tctcagttgg aatatgctgg gcatgtcctc
    27181 tcatgacttg ggcaatggct gtacgttctt caggtgtttc ccccttcatc ttaagagcta
    27241 agaggagaga agcaatctgc gcttcagtta cacgcccagt tacgatacgc tcaatgacat
    27301 ccgtcatttc cacacctgat aaattttcaa attttgctag tttttcaata atctctttca
    27361 tcctagtttc ctcactttac aaccttctcg ataaaattcc gaatagaaga caagccgtct
    27421 ggcgttccaa tgctctctgg atggtactgg aagccataaa tcggtaggtt tttatgttga
    27481 atccccatga tggcttggtc atcagtcgaa cgagctgtca cttcaaagtc ttctggcatt
    27541 tcctcaatca aaatactgtg ataacgcatg accgcacgtc catcctcaat accttgatac
    27601 aaaacagatg gcgcttcaaa gttgatattg ctctgtttcc catgcatgac ttttggagcc
    27661 aaacctagct taccaccaaa gacttctgca atggcttggt gacccaaaca aatccctaga
    27721 atcggcttct tgcctgcaaa atcacaaatc atgtcttcca tctttccagc atcaactggc
    27781 caaccaggac caggagaaaa gaccagacca tctgcttttt cagcttcttc atacagcttg
    27841 gaatcatcat ttctcaaaac ctgaacttct gcaaaattcc caatgtattg ggccaagtta
    27901 taggtaaaag aatcatagtt gtcaatcaat aaaatcatgg tcttagttct ccaattctag
    27961 tcatagattt tgctttgtta atggtttctt ggtattcgtt ttgggcgata gagtcgtaga
    28021 caatccctgc cccagcctgc acataggctc tttgattttt gagaatcatg gttcggatgg
    28081 caatggccaa atccatatca cccgtcgcag acaagtagcc gattgctcct gcatatacgc
    28141 tccgtttttc cgtttccagt tcatagatgc gtctcatagc tcgaattttt ggtgctccag
    28201 aaacggttcc agcaggaagc gttgctttca aggcatccat ggcagtgagt tctgcaagca
    28261 aacgtccctt gaccacactg gtcaaatgca tgacgtagcg gaagagctcc acctccatat
    28321 acttagtaac ttggacactg gccgtttcag agatgcggcc aatatcgtta cgccccaagt
    28381 ctaccaacat tcgatgttct gctgtttcct tctcatcaga gaggaggtca gtcgccaagg
    28441 ccttgtcttc ttcatccgta gcccctcttg gtcgcgtccc tgcaatcgga ttggttgtca
    28501 cgatgccatt tttgacagaa accaaacttt ctggactagc tccgatgatt tgataatccc
    28561 caaaatcata gaaataaagg taattagatg gattagtcac gcggagattt ctgtagaagt
    28621 caaatggatt tccagtaact tctgctgaga aacgctggct gagtacacat tggaacatat
    28681 ctccgttacg aatcaagtca cgagctgttt ctaccattcc ctcaaactta tgtggagcga
    28741 tatgcggttt gaagtcaagt ggtgataaat ccaagtcttc aaattcattt ggagcaggaa
    28801 tgcgtaattc ctcaagcact tggttcaagg atttttccaa ggcctcttga ctgcgctcac
    28861 tataaagtgc atcctctatg acatgtatct tctccttctt gtggtcaaag accatatagc
    28921 tctcatagac aaagaaatgc atgtctggcg tcccaattgt atcctcaggg atttgaccaa
    28981 tttcttcata aagcgaaatc atatcgtaac caacaaaacc aatggctccc ccaccaaaag
    29041 ggaggtctga atggtgctgg ctcttatgag tcacttcata aaggaaatcc aagggatccc
    29101 gatcaatcgc ttgaccattt tgatagagaa ctccattttc aaacttaatc tcaaaaactg
    29161 gattataggc taggatagaa aaacgagctg tttccttgtc tctcggaata ctctctaaaa
    29221 taaccttatg ttgccccttt aagcgcatat aagccaagat tggtgataag acatctccat
    29281 gaatgattcg ttccattgtc atttcccttt cagttctaat tctagttcgt ggcgactgta
    29341 tgaaaaatcc ccacgcaaaa taacttgcgt gaggacgaaa ttcgcggtgc cacctcaatt
    29401 ataggatttc tcctatctct cattcctgtc tcagatatct cctgtaacag gctgtgcgat
    29461 aaagggcact cccttgagaa tgatgttttc ttctctcgtt tcagatgaac ccaactttac
    29521 agctttctct gcttgttttc agcaaccaca agctctctgt gagagaaaag actgtaattt
    29581 ttccatctat tattttttag cttctagtaa tctgcaatcg cagctaggtc cttgcctcca
    29641 cgaccagaga cattgatgaa gagatgttca tctcggtaca cctttatact cttcgaaaat
    29701 ctcttcaaac cgcgtcaacg tcgccttgcc gtaggtatgg ttactgactt cgtcagttct
    29761 atctgcaacc tcaaaacagt gttttgagct gacttcgtca gttctatcca caacctcaaa
    29821 acagtgtttt gagcaacctg cggctagttt cctagtttgc tctttgattt tcattgagta
    29881 ttactagctt ttttcgtatt agtccagcct ttttgtttac ttttagtagg aggcaaggag
    29941 ctgtagatag aactcaagtt catcaaagcg acttaaggcc ctaataaaag ataaaccaaa
    30001 cgacggatag aaaaaagccc acacacagaa tatacttccg tgtgagggcg ttggtaacgc
    30061 ggtgccacct caattataaa gggactatcc ctttacatct ctgccttgtt taacaacaag
    30121 ctgcactgta aggtgtgcgc accgaatttt cattgtttca aattcatttt caaaatcagc
    30181 ccactttcac tacttccaac cacctattca caatcaccac aggctccctg aagatcaaaa
    30241 atagttactt ttctgatttg ttgaacttat tttaatactt tgttttttct ttgtcaagac
    30301 ttttttacga tttttttgat atcattcgaa tgtgaccata tcttccttag atcgaacatg
    30361 aacatgtccc acttgttaga aattggatcc aactcaatag aaactgaatg gaggctaaac
    30421 agaacttatt ttagaacact ccatcttttc cactaggatt ttcaagaatt aaacaatact
    30481 agaaactctg tctcctaaca aatttaggag aaacttcaac agatgtgaca ctttcccctt
    30541 taataattgc taaaacacct tctatcattt ctttagccaa tttaacataa ttgggagcaa
    30601 ttgtagacaa agctggagta taatactgag aaataggaat attatcaaat ccaatgatag
    30661 aaatatcatc tggaataaga attcctttct catagcacgc acgaatcaag ccctgaacct
    30721 tttcatctcc tgaaacaaaa ataatgtccg gataattttg ggtagtcaag tgctgcattg
    30781 cataagaata aactgaatca attgtagata agccataaat gacttttaaa tccataaagt
    30841 aatttttatc attcagaaaa gaacgcacac ctctttcacg atccttatta acatgggatt
    30901 ctcctcccat aagcaaccac atatttttaa atttttcttc agttacagct ttcatcatat
    30961 cataagtagc ttgaaaatta ttattagata catagactac tccagacgtt tgagattcac
    31021 cgaaaacaag aaaaggcata tggttcttct ttaaatactg aattctgata tcatctacac
    31081 tttcataaaa aacaataaca ccatctacta ggctacctgt gcttgatata attgaattac
    31141 taattgtatc ctcctctcca aagtactcaa ctatagcatt aacaccaaat tctttacacg
    31201 tccgtaacac tttatctaac agcgtatgaa accaaattaa aggaaaagag tcgatttttt
    31261 ttacagaaat caatatattt atagcttctt ttttagttaa attttttgca tacgcatttg
    31321 gaatatacga caattcctct ataacttttt gaatcgcttg ataagtttct tctttaacat
    31381 ttactccacc attaataact cgtgaaactg tttttggaga aaaacctgat aaacgtgcaa
    31441 tatcataaat agttaccttt ttcccattta tatttttcat ttcagtcctc cattacgaac
    31501 attctaatat tactatacaa tatttaattt tttttaacaa gagaatttag taaattattt
    31561 aagatccaca aattcacaaa attaatttta caaatattct tccccttcaa aaaaatttaa
    31621 attgcatttc acacctttat ttttaagaat gtttccaact tcacgacaaa taaattcata
    31681 tgagaaaaaa ctgccataaa attgtagatt aactttttca gtaaaatgtg taggatttat
    31741 aaaaacatat aatagcctgt caatgtaaca ttttaacata gagttaattt tttctttaaa
    31801 gataacattt gttatcaact catcaggagg taaatgaaag gcaaacacca tttcacaaat
    31861 atcataaaaa gaaataaatt tgtatacttg tatcaaacaa ttattatcaa aatattctat
    31921 tttacctaaa tcaaaattga ttttataatc tttcataaaa acctctgagc aaaaatctac
    31981 tcaaaaatta gatgattaaa acatctaaaa aacaaaagga caaaaacatc tgtccctttg
    32041 tttactaaat ttcagctaat ttcttcgaca taaataacac ctacaatatt agcaatttct
    32101 tccatcagtc gaagatgttc aaatctacct gataattcca gagtaataaa tgacgctatt
    32161 tttttatctg gaacatcaaa gtattcaatt ctgtcagaat taacatctcc aaacgctgtt
    32221 cttgaatcgg tcattctgat accattttct gcacaataaa ccaatacacg attataggct
    32281 tctgtagatt taaccactat atacaattca atcattttag aacgattttg tagatatttt
    32341 tttagtggtt ggaacatgga tatcacaccc caaacagaaa tggctactaa aagagctccc
    32401 tcataaaaac ctactccaat agctaatcca attcctgccg aagcccaaat gcctgctgca
    32461 gttgtcagac ctgtaatttt ctttttatct gtaataagaa tcgttccagc gcctagaaaa
    32521 cccacacctg atataacttg agctcctaat cgtgtaggat ctcctgtccc aaatttataa
    32581 gatacgtatt cattcgtcat cataatcaaa catgcagcta gacaaacaat actataagtt
    32641 cggatgcctg caggctggga tttgctccct ctctctaaac caattatact accaatgact
    32701 actgataaaa caatcctgac aactatttca atatttgata acccaagact agtggctgtc
    32761 atgattattt ccttacttta cgccccggtc tttgtgtgaa gtataatacc gttccagaaa
    32821 taatcatcag aacaattgta taaacaaata ccagagcttg tgcattagat gttgctgttt
    32881 catcacctgc agatcgaatc gtaataccta atggttgagc taggggatgg taaaggaata
    32941 cagataagtc gaagtcagtt aataaagagt taaagtttaa agcaataaca gagagaacaa
    33001 ccggtaaaat aaatggaatg ataaccttca tcatagtata aaaaggtgaa gcacccatac
    33061 ttcttgctgc atcttccatc tcatcatcaa cactaaataa aatagcacgt accattctat
    33121 aagaaaatgg gatttttaca actatatatg caataagtag aattaccaaa ctacctacca
    33181 aaatctgatt caagacaaga aattgtggct gattaaaagt aaataataaa cttactgcta
    33241 aaagcgtact tggtaataac caaggaagta gagcaccata ttcaaataag aaatcaaaac
    33301 gagatttatg ttttctgaca acacgagcaa atacaactgc gagaattgtt gctgttgtcg
    33361 cagcaataat agaataaata aagctgacca agaatggaga gaatgccgca ctattactaa
    33421 agaataagcg ataattttct aaagtaaagt ttgataatgt taagttacct gtttgaattg
    33481 caactggatc tgtaaatgag tataatacta taaaaattag tggaagcatg aaaactgtga
    33541 acaatccata tgctacaatg tgagcaatga tattccaagg cttagacgca attttttgtt
    33601 ttttaagagg cgctttagtc ttagagatag aaatataatt tccacctttt tctatcttat
    33661 tcatgatagt aagcaaaatt gtagttgcaa tacctaaaat aattgcaagt aaggcagcta
    33721 aatcacgaga attccccatc cctgcaaatg taataatcat tggatttata gtttgaaatt
    33781 ctttaccacc aacaatcatg ggtgctgcta ctgcagataa accactaaga aaaaccataa
    33841 tagtaagtgc aaatagagtt ggaattaagg ttggtaacac tacttttcgg aaaacagtaa
    33901 atggttttgc tcccatattt cgagcagcct caatagtgtg atagtcaacg cttcgaattg
    33961 tatttgttaa aaacaatgta tgattagcag ttcctgaaaa tgtcataatg aataagactg
    34021 caccataccc aataaaccag ttagggtcta aagaagggat aacattttgt aaaaattttg
    34081 taatcaatcc atatggacca tagacaaatt tatatccagt cgctaaaacc actcctccat
    34141 aaattaaaga ggtcatataa cctaatttta aaattttagc acctttaata tcaaagtact
    34201 ctgtaaatag aacacaaaga atacctacga cattaactgt aataatgagt gaaaatgcta
    34261 acttaaaact gttcataata ctctgaagtg ccctctgaga ttttagaaca cgatgtacag
    34321 catcaaggga aaattctcct ccttttacaa atacattcac tactagatca aagtttggat
    34381 aaataataaa tgttactaag aaccagatta accctaaacg aataagccaa tcttttaaat
    34441 ttaatttatg acgcatactg cacctcctta aaattgcaga acgtctgatg gtgtgataaa
    34501 taattccaca ctttctccga cagatctaat agcagcctga ctatcaatac ttgttacatt
    34561 aagaatctga ctttcagaaa cttttattgt atagtgaatt gtaactccag aaaactcaac
    34621 atcaataatt gtccctttta gaatgaaatc ttgttcagtt tcacgattga atcgaacttt
    34681 ctctaatcga atgtatcctt ttttatcttc taagaaaacg cttgtatttt tcagtaatac
    34741 ttcgtggact gtttcatcgg tcaaaacatt aatatctcca ataaaatcac atacaaattc
    34801 agtttgagaa ttatgataaa tctctactgg tgtaccgacc tgttcgatgt atccattgtt
    34861 aaagactgca attctatcag ataaagtcaa ggcttcctct tgatcatgag taacatataa
    34921 agtagtaata cctaactctt tttgaagtct tttcaactct tttctcaaat ctacacgtaa
    34981 ttttgcgtca aggtttgaca atggttcatc tagacaaaga attttaggtt caagaaccag
    35041 agcacgagcc aatgctaccc tttgttgttg acccccagat aattctgata cattacgctg
    35101 taactgttga tcagagatct taatttttgc tgccactgct gatactttag ctttaataac
    35161 atctggagct accttcttaa cttttaaacc aaatgcaata ttatcaaaaa cagtcatagt
    35221 tggaaatagc gcataagatt gaaatacaat accaattcca cgcttttcag gttccaaatg
    35281 agtgacatct gttccattaa cttcaatact tcctgatgat ggatctaaaa aacctaccaa
    35341 tgctctcaaa gtagttgatt taccacatcc tgaaggccca agaaatgtaa agaattcccc
    35401 ttcatgtata tctaaattca gattatcaat tgcaacaaaa tcaccatatt taatttgaat
    35461 attatcaaat ttaatcatct cactaactcc ctctattact aaaccaaaag cctctcttta
    35521 tttcttcctt aaatttagaa ataatagaga gacttggaca taaaaaataa ctcttatttc
    35581 ttattttacg tattctaatt cagctttttc tacccattca tccaaatgct ttccaacagc
    35641 ttcccagtca atattttgtg gtttcacttg atcaacaaat tttttcgtat cttcaggtaa
    35701 ctcttttagg gcatctttat ttgcaggaat agatccaaat tttttactat attctacttg
    35761 aatttctgat tgaccaaacc aatcaataaa ttctttagct aacgcttgtt ttttactagt
    35821 gcttaaaacc atagtttgtt cagttacaaa tggtacacca atctcaggag tcataacttt
    35881 gaattcaaca ttttgttctt tttgtccgat taacgctcca gaaccccaga tcataccgta
    35941 ttgaattggg ctttctttat ctaacgcttt aacaactgag ctttcacctt tttgaagagt
    36001 ataggcattt gcaaagtatt cttttgcaac ttcccatcct ttttctgata cgcctaaatc
    36061 tcctttttca tcaaggtaac gaactaagat acttgctaga attgcccgtc ctgtaccacc
    36121 ttgaagacca taaattgaat atttaccttt atacttacta cctaattcag tccaatcttt
    36181 aggcatttct tttacatcag gcgccccaat taaaactaat ggttgaacaa tcacaggatt
    36241 ataataatta tctttatctg ataaagattg atcaatttta tctaaccatt taggcttgta
    36301 ctgtactagt aatttttgat ctctaatttt atttgagtca acagcaccaa ttccaaatac
    36361 catatctgca actgcattat tcttctcagc aataacacgg tctgctaatt gagcgccagc
    36421 aatatcaacc atttttatat taaaaccagc ttcttttgct ttagcagtta accaatcacc
    36481 acgaccattt gagactgagt tcgaatagat tactaattct tgacttttat cagctttttc
    36541 ttcagatgaa gaagcagtcg tagaatttga acctccagag caagcagcaa gtgtagtaag
    36601 agcaactccc gttgcaagta cagtagacca aactttcatt tttttcatga taagttctcc
    36661 ttttttatta ttttatttaa atttttcgtg atatggaaca aattgtctca tatcttcaaa
    36721 tacagtatag tcaatacggt ttacagtaat agttggaatc ttctctaata aaatttcagt
    36781 taattctgct ctgactttag taaactcttc ttcctcctct tcggttagag gaatccgaag
    36841 atacccaatt gaaatatgga attgatatct atcatgatta gggaaacaaa cacctgcttt
    36901 ttctgagaca taagtacgaa tttcttctaa tctctttgca gaagcttcat ctgcaggttc
    36961 aactagtatg ttttgttttc ccatttcagt tatacgcata tgaatttctt catccaacaa
    37021 tggaaaaatt tcaagttgtt tagcaaagta atcatgtatt tcctgtaaag gtgtatctag
    37081 aggaagatta ctgctccaaa actccgtttc acgattttca tggcacaaca attcaattac
    37141 agtcatgtga atagaattcc ttggagttaa agtaaactta tcgataaatg gtaattctct
    37201 ataacgtgat tgaataatat caacaacttc catcaaatct tgtttagtat aaagatttgc
    37261 tacaactgta ttcccaggga aatgattaaa ttccccattc tctttgaact taatttttgt
    37321 taagtttttc atataaagac cttctttttt atatttgaca tcggtgtcat tgtgtttaca
    37381 ttatacaatg aaaccgtttc ctttgtcaag cgctgtcaaa catttttttt aatttatctt
    37441 tcattaaaag
//
LOCUS       DAVAZV010000016        34347 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVAZV010000016 DAVAZV010000000
VERSION     DAVAZV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.016"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..4786
                     /locus_tag="VQT46_000786"
     CDS             <1..4786
                     /locus_tag="VQT46_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2370841.1"
                     /translation="QGERGLTGAKGEKGDQGERGLTGAQGEKGDRGERGLTGAKGEKG
                     AQGQAGRDGVTPTVTVKDNKNDGTHTITINDGRGNVTSTVVRDGFDGASPLVATQRND
                     ADKTTTVIFYYDKNGNNELDASDKKLKEVVIADGAKGEKGDKGEQGLQGRDGEQGPKG
                     EDGKTPTVKVTDGQDGTHTITINDGKGGITTTVVRDGFDGASPLVSTHRNEADKTTTV
                     IFYYDLNDNNQFDEGDTKLKEVVIADGKQGPKGDKGDNGKDGFTPEVTVTDNNNGTHT
                     ITITQPDNRPSLTTIVKNGEDGKTPKVKAERDDAKKQTTLTFYIDKDGDGSYTAGKDE
                     LVQTTVVKDGQDGAAGASGRDGKEVLNGKVDPTTEGKDGDTFVNTQTGDVFVKKGNTW
                     EPAGNIKGPKGDKGADGAKGEKGAQGERGLTGAQGVKGEKGDQGERGLTGSKGEKGDQ
                     GERGLTGAQGAKGDKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPGKDG
                     KSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSVQNG
                     KNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPDVTT
                     TIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEGNIK
                     GPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEAHQG
                     KDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDGHST
                     DITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENNDGK
                     YTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPEKPL
                     AVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGATGQD
                     GQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSPSRI
                     RRDTDAAATPTRNGIRVTVYDDVNDNGVYDEGVDKVLNSKDIYNGIDGRDGSAPTITT
                     KDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGSTKE
                     TVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTENPD
                     GSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTTETT
                     VRDGKSPKVTITDEQNGTHKISVLNGDGTTTTTTVRDGREPKLEVIDNNDGSHTIKVT
                     GADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSIIKDGKDGKDSVSPT
                     VTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGDGSHTITIINSDGT
                     VTKTVIKDGRDGRDGRDGKDGKDGKDGKCGCQDKPVTPSNDKPVPPTPNVPTPEVPVK
                     PVPAQPTPNVPTPEVPVQPTPAVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVA
                     PTTGKENRGDKLPETGSQSDYISVLLGSGILLSLYVGRRKEA"
     gene            complement(5023..5571)
                     /locus_tag="VQT46_000787"
     CDS             complement(5023..5571)
                     /locus_tag="VQT46_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2370842.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            5892..6380
                     /locus_tag="VQT46_000788"
     CDS             5892..6380
                     /locus_tag="VQT46_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET2370843.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            6377..7564
                     /locus_tag="VQT46_000789"
     CDS             6377..7564
                     /locus_tag="VQT46_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2370844.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTVILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            7557..7922
                     /locus_tag="VQT46_000790"
     CDS             7557..7922
                     /locus_tag="VQT46_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2370845.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGAPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            7938..9284
                     /gene="asnS"
                     /locus_tag="VQT46_000791"
     CDS             7938..9284
                     /gene="asnS"
                     /locus_tag="VQT46_000791"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET2370846.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            9437..9727
                     /locus_tag="VQT46_000792"
     CDS             9437..9727
                     /locus_tag="VQT46_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET2370847.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            9739..10209
                     /gene="ssbA"
                     /locus_tag="VQT46_000793"
     CDS             9739..10209
                     /gene="ssbA"
                     /locus_tag="VQT46_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET2370848.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            10241..10480
                     /locus_tag="VQT46_000794"
     CDS             10241..10480
                     /locus_tag="VQT46_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET2370849.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            10775..12175
                     /locus_tag="VQT46_000795"
     CDS             10775..12175
                     /locus_tag="VQT46_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET2370850.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSYVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDVIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            12177..12536
                     /locus_tag="VQT46_000796"
     CDS             12177..12536
                     /locus_tag="VQT46_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET2370851.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            12590..13339
                     /locus_tag="VQT46_000797"
     CDS             12590..13339
                     /locus_tag="VQT46_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET2370852.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            13329..13628
                     /locus_tag="VQT46_000798"
     CDS             13329..13628
                     /locus_tag="VQT46_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET2370853.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDMRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALFKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            13699..14634
                     /locus_tag="VQT46_000799"
     CDS             13699..14634
                     /locus_tag="VQT46_000799"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET2370854.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            14721..15233
                     /locus_tag="VQT46_000800"
     CDS             14721..15233
                     /locus_tag="VQT46_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET2370855.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGAVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            15270..15865
                     /locus_tag="VQT46_000801"
                     /pseudo
     CDS             15270..15865
                     /locus_tag="VQT46_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            15966..16160
                     /locus_tag="VQT46_000802"
     CDS             15966..16160
                     /locus_tag="VQT46_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET2370856.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(16206..17651)
                     /locus_tag="VQT46_000803"
     CDS             complement(16206..17651)
                     /locus_tag="VQT46_000803"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET2370857.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            17757..19379
                     /locus_tag="VQT46_000804"
     CDS             17757..19379
                     /locus_tag="VQT46_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2370858.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            19583..21541
                     /locus_tag="VQT46_000805"
     CDS             19583..21541
                     /locus_tag="VQT46_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370859.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVASKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGFLQNLGLEPGEANDKAKAVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFATAYGLTGTKGVESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            21713..22648
                     /locus_tag="VQT46_000806"
     CDS             21713..22648
                     /locus_tag="VQT46_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370860.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERV
                     QNNSLKSDRVTSFETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLL
                     NPISNIANFVTVYSRSKGSSVALENLLAVPKEKFE"
     gene            22673..23325
                     /locus_tag="VQT46_000807"
                     /pseudo
     CDS             22673..23325
                     /locus_tag="VQT46_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864981.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            23483..24577
                     /locus_tag="VQT46_000808"
     CDS             23483..24577
                     /locus_tag="VQT46_000808"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2370861.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            24585..25751
                     /locus_tag="VQT46_000809"
     CDS             24585..25751
                     /locus_tag="VQT46_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2370862.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            25844..28942
                     /locus_tag="VQT46_000810"
     CDS             25844..28942
                     /locus_tag="VQT46_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2370863.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            28990..29607
                     /locus_tag="VQT46_000811"
     CDS             28990..29607
                     /locus_tag="VQT46_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET2370864.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            29617..30951
                     /locus_tag="VQT46_000812"
     CDS             29617..30951
                     /locus_tag="VQT46_000812"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET2370865.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            30961..31425
                     /locus_tag="VQT46_000813"
     CDS             30961..31425
                     /locus_tag="VQT46_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370866.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            31422..31916
                     /locus_tag="VQT46_000814"
     CDS             31422..31916
                     /locus_tag="VQT46_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370867.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            31997..33646
                     /gene="mltG"
                     /locus_tag="VQT46_000815"
     CDS             31997..33646
                     /gene="mltG"
                     /locus_tag="VQT46_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET2370868.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMTDSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDIIS
                     DTSRRSRREGAKPVNPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPIDA
                     NSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQKSM
                     STEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAFLA
                     KVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDEML
                     AAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDMPL
                     QSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIESSI
                     NQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            33717..34199
                     /gene="greA"
                     /locus_tag="VQT46_000816"
     CDS             33717..34199
                     /gene="greA"
                     /locus_tag="VQT46_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET2370869.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
BASE COUNT        10715 a         6373 c         7776 g         9483 t
ORIGIN      
        1 ccaaggtgaa cgcggtttaa ctggagctaa aggtgaaaaa ggggaccaag gtgaacgcgg
       61 tctcactgga gcccaaggtg aaaaaggaga ccgaggcgaa cgtggtttaa ctggagctaa
      121 aggtgaaaaa ggagcccaag gtcaggcagg tcgtgacggt gtaactccaa ccgtaaccgt
      181 taaagataat aaaaatgacg gcactcatac tatcactatt aacgacggta gaggtaatgt
      241 tacaagtact gttgtaagag atggtttcga tggcgcaagt ccattagttg cgactcaacg
      301 aaatgacgca gataagacaa caactgttat cttctattac gataaaaatg gaaacaatga
      361 attagatgct tctgataaga aattaaaaga agttgtaatt gcagatggtg ctaaaggtga
      421 aaaaggggac aaaggtgaac aaggtcttca agggcgtgat ggtgaacaag gaccaaaagg
      481 agaagatggg aaaaccccaa cagttaaagt aactgatggt caagatggaa cgcatacaat
      541 tacaattaac gatggtaaag gtggtataac tactacagta gtaagagatg gatttgatgg
      601 tgcaagccct cttgtttcta ctcatagaaa tgaagcagat aaaacaacaa ctgttatttt
      661 ctattatgat ctaaatgata ataatcaatt tgatgaagga gatacaaaac ttaaagaagt
      721 tgttatcgca gatggaaaac aaggaccaaa aggtgacaaa ggtgataacg gaaaagatgg
      781 attcacacca gaagtaacag ttacagataa caataacgga acacacacca tcacaatcac
      841 acaaccagac aacagaccat cattaacaac aatcgttaaa aacggtgaag atggaaaaac
      901 accaaaagtc aaagcagaac gagatgatgc gaagaaacaa acaacattaa cattctacat
      961 tgacaaagat ggagatggaa gttacacagc aggaaaagac gagttagttc aaacaacagt
     1021 agttaaagac ggacaagacg gagctgcagg agcatctgga cgtgatggaa aagaagtatt
     1081 aaacggaaaa gtagacccaa caacagaagg taaagatgga gacacattcg taaatacaca
     1141 aacaggagat gtattcgtta agaaaggtaa cacttgggaa ccagcaggaa acatcaaagg
     1201 accgaaaggt gacaaaggtg cagatggtgc caagggtgaa aaaggagccc aaggagaacg
     1261 cggcctgact ggagcgcaag gtgtcaaggg tgaaaaggga gatcagggtg aacgcggtct
     1321 aactggatct aaaggtgaaa aaggagacca aggtgaacgc ggtttaactg gagcgcaagg
     1381 tgccaaaggt gacaaaggtg aacaaggtct tcaaggtcgt gatggagctc aaggaccaaa
     1441 aggcgcagat ggacaaagag gaccagcggg accacaagga ccaaaaggag aacaaggtaa
     1501 tccaggaact ccaggtaaag atggaaaatc tctaattgct gttaaaaatg gaactgaaac
     1561 aaaagtctat gtagaggatc cggctagacc aggacaacca cttaatccaa accaaccatt
     1621 agcaactatc actgatggaa gaaacggtac taatggacaa tcaccaacaa ttacagcgac
     1681 acgaagtgtg caaaatggca aaaatggtgt attagtaaca attacaccag taggaggtcg
     1741 tccacaaaca acatttgtag aggatggaca aaagggtgct gatgggaaaa ccccaacagt
     1801 aacaataact gaggggcaaa acggcacaca tacattaacg gttcataatc caggaagtcc
     1861 agatgtgaca actacgatcc gtgatggagc tacaggacaa gcaggtcgtg atggtaaaga
     1921 tgtattaaac ggaaaagtaa atccacaacc aaaccaaggt aaaaatggag ataaatatat
     1981 taataccgaa accggtgatg tctatgttaa aaacaatgga aactgggata aagaaggcaa
     2041 catcaaaggc cctaaagggg acaaaggtgc agatggtgct aaaggcgaaa aaggagacca
     2101 aggcgaacgc ggcctaactg gagcgcaagg agctaaaggt gcggatggcg cagtaggtcg
     2161 tgatggacgt gacggtaaag acgtgttgaa cggcaaagct aacccagaag cacatcaagg
     2221 taaagacggc gataaatacg ttaatacaga aacaggcgac gtcttcgtta agaataacgg
     2281 caactgggat aaagagggca acatcaaagg ccctaagggt gacaaaggtg aacgcggaga
     2341 agatggtaag actccagaag taactgtaac tccaggtaaa gatggccata gtactgacat
     2401 tacattcact gttccaggta aagatccagt tacagtaaat gttaaggacg gagaaaatgg
     2461 tctgaacggt aaaactccaa aagttgattt acttcgtgtc caaggaaaaa acggaaatcc
     2521 atctcataca attgtgacat tctatacaga tgaaaacaat gacggcaaat atacaccagg
     2581 aactgatgaa cttctaggtt cagaaatgat taaagatggt gctaaaggcg cggacggacg
     2641 agatggtaaa tcattgctta ctgtcaagga tggtaaagaa actaaagttt accaagaaga
     2701 tccagctaac ccaggacaac cattaaatcc agaaaaacca cttgcggtaa ttagagatgg
     2761 agtagatgga aaatcaccta cagttacagc tgttcgtaaa gatgaagcag ggcataaagg
     2821 tgtagaaatc actgttgata accatgatgg ttcacaacca actacagtct ttgttcaaga
     2881 tggtgctaag ggagaaactg gtgcaaccgg tcaggatgga caaactccta caatcactac
     2941 tcaacgtgga caagatggcc aaagcactgt tgtaactatc acaacatcag gtaaagatcc
     3001 agtaaccttc actgtaaaag atggtaagaa tggtaaagat ggccgtgcac cgaaaatcaa
     3061 agtagaagat attacttcac cttcaagaat tagacgcgat acagatgctg ctgcaactcc
     3121 aacgcgtaac ggtatccgtg ttacagttta tgatgatgtt aatgacaatg gggtatacga
     3181 cgaaggtgtc gataaagtat taaatagtaa agatatttat aacggtatag atggacgtga
     3241 tggttcagct ccaactatta ctacaaaaga taatggagat ggaactcaca ctatcacagt
     3301 tcaaaaccca gatggttctg aatcaacaac agttgttaaa gatggtaaag acggtaaaac
     3361 tgcgaatatc actacaacag aaaacccaga tggaagccac acaattacgg tgacaaatcc
     3421 agatggttca actaaagaaa ctgttgttaa aaacggtaaa gacggtaaga ctcctaaagt
     3481 tgaagtaacg gataacaacg atggaactca tactgttaaa gttacagatg gagacggcaa
     3541 tgttaccaac gctatcatca aagatggtaa agacggtaaa gctgcaacag caacaactac
     3601 tgaaaatcca gatggaagcc acacagtaac aatcactaac ccagacggaa ctaagaatga
     3661 gtttgttgtt aagaatggac gtgacggtgt tgacggacgt actccaaccg catctgttcg
     3721 tgataatgga gacggaagtc atacaatcgt tattacaaat ccagaaggtg tgacaactga
     3781 aaccacagtt cgtgatggta aatcaccaaa agtgactata actgatgaac aaaatggaac
     3841 tcataagatc tctgttctaa atggtgacgg aacaactaca acaactacag ttcgtgatgg
     3901 tagagaacca aaacttgaag ttattgataa caacgatggt tcacacacta ttaaagtgac
     3961 aggtgctgat ggtaaaggaa cgacaactac aatctttgat ggtaaatcac caaaagcgaa
     4021 catcgttgat aacggagatg gaactcatac attaacaatc gtagattctg atggtcgtga
     4081 atacaaatct attatcaaag atggtaaaga cggcaaagat agcgtttcac caactgtaac
     4141 tgttaaaaat aataacgatg gaactcacgt tgttacaatc actaatccag atggaagtaa
     4201 gacagaaatg gtgattaaag acggtaaaga tggtaaatca ccaaaagttt ctgttgaaga
     4261 taatggtgat ggtagtcata caatcacaat catcaattct gatggaactg tgacaaaaac
     4321 agttattaaa gatggtagag atggacgtga tggtcgagac ggcaaagacg gtaaagacgg
     4381 taaagatgga aaatgtggat gccaagacaa accagtaaca ccatcaaatg acaaaccagt
     4441 tcctccaaca ccaaatgtgc cgacaccaga agtaccggtt aaacctgtgc cagcgcaacc
     4501 aacaccaaat gtaccgacac cagaagtgcc agtacaacca actccagctg ttccaacacc
     4561 agaagtaccg gttaaaccag taccagcggt tccagaacaa ccagtagtac caacaccggc
     4621 tcaaccagca actccagtaa atgctaaccc agtagcacca actacaggta aagaaaaccg
     4681 tggggacaaa ttacctgaaa ctggaagcca atctgattat atctctgttc ttttaggtag
     4741 cggtattcta ttgagcctat atgtaggacg aagaaaagaa gcttaatcag ccaaaagcag
     4801 tcactaattt ctcgaaagaa gatgataagt gatagatctc gaatgaaaga atattcttag
     4861 aatgattttc ctatgatgga aaagactgct aaaaaccttg agtggtaacg ctcaaggttt
     4921 ttttggatgg ctgatgtttg tctgaaaatc ttgattgaga aataaaaagc caccctatta
     4981 ggtggctata attgatttag actttctaaa attttctatt ttttactgaa tcgcttcgac
     5041 caagtcttga gcttgttttt caagtgagtt taggactgtt tcttcaagaa ccaattttcc
     5101 gtctgcccag gcagagtcat taacacgtgc agcagtgaaa tcaccaacgc cttgtgtacg
     5161 gataaatggc aagaggtctt tgtagatagc gaaaagttga tcgtgccctg cattggctac
     5221 agatgatacg gtgacaaact tgtcttgaag ggcagaaacg ccacgcgtat cagacaagtc
     5281 aagggcacga gatagccagt caagcaagtt ttttactgta ccagggatag agaagttgta
     5341 gactggagag aaaatccaga tagcatccgc aacgagaact gcttcacgag cagcagctac
     5401 agctggatgt gttggaactt ccaaatcttg gctgaagaga ggaagggctg aataatcaag
     5461 gtagctaact tccgctttac cagcaagtgc tttctcagct tcgagcgcca tttggtggtt
     5521 gaaagaacct tgacgtagtg atccgacgat aaataatact tttttagaca tgatgtgtct
     5581 cctttttctt caaattttga gaactctctc gttgttataa aatacattac aacaaaacaa
     5641 aagaacttgc aagaaatttg ctcagagttt atttgaaaat tgtaaaattt cggaaactct
     5701 agtcatttgt gactgaaaaa gtaagaactg tttcactttc aaaatcggtt ttgtttgaag
     5761 ggagaaatag aattggttgc tcaaagcaca gctttgaggt tgcagataaa gctgacgtgg
     5821 tttgaagaga ttttcgaaga gtattcttat attcacttgt aataaagctt aatagatggt
     5881 aaaatagacg agtgaaaaaa agacaaaaca aagcaaaaaa taatctactg tggcagtatg
     5941 gtctagggat gacgattttg tttgtggtta tcagtgcttc ctttctgtat atggtttctc
     6001 ttagcatgaa accctatcaa acagctaaaa gtgaaggaga aaaattagct cagcagtatg
     6061 caggattaga gcaggccgat caggttgatt tatacaatgg cttggaatct tattacagcg
     6121 ttcttggtcg taataaacag caagaagcac ttgctgttct gattggaaaa gatgatcata
     6181 agatttacgt ttatcagcta aatcagggtg tttcacaaga aaaagcagaa acggtttcta
     6241 aggaaaaggg agctggcgaa attgacaaga ttatctttgg tcgttatcaa gataagccaa
     6301 tctgggaagt caagtcagga tctgattttt atctagtaga ttttgaaaca ggagcattgg
     6361 tcaacaagga gggcctatga aattatccaa ccgtgtttta gaaatggaag aaagtgtgac
     6421 tttggctgct ggagcccgtg ccaaagcact gaaggctgag ggtagagata ttttgtctct
     6481 aaccttgggt gagccagatt tcactactcc caaaaatatc caagatgccg ccattgcatc
     6541 gattcgagat gggcgtgctt ctttttatac agtaacctca ggtctgccag agcttaaggc
     6601 ggcggtcaat agctactttg agcgctttta cggctattct gtagcgtcaa atcaagtgac
     6661 agtcgctgcg ggagccaaat attctctcta taccttcttt atggctgtgg tcaatccagg
     6721 tgatgaagtc atcatcccaa ccccatactg ggttagctat ggagatcagg tcaagatggc
     6781 agaaggcgtt cccgtctttg tttctgctaa ggaagacaat cactttaagg tgaccgtaga
     6841 gcagttagaa gcagctcgca ctgacaagac caaggttttg gtgctgaatt cgccatctaa
     6901 tcccacaggt atgatttaca cccgtgagga actcttggca attggaaact gggctgtaga
     6961 aaatgatatt ctcatcctag cagatgatat ctatggccgc ttggtttata atggtcatga
     7021 gttcacaccg atttctagcc tatcggaagc gattcgcaag caaacagtgg tcatcaatgg
     7081 tgtgtctaaa acctatgcca tgactggttg gcggattggt tatgccgttg gagaagcaga
     7141 cattatcgct gccatgtcca agattgcagg tcaaacaact tcgaatccgt cagcagtagc
     7201 ccaatatgca gcagttgagg ctctatcagg tgagcaagat actgtagaaa gcatgcgtca
     7261 ggcctttgaa gaacgtctta ataccatcta tcccctcctt gcagaagtgc caggatttga
     7321 agtggtcaaa ccgcaagggg ccttctatct cttcccaaat gtcaaaaagg ccatggagat
     7381 gaaaggctac acggatgtga cagactttac aactgttatc ttagaagaag ccgaagtggc
     7441 cttggtaaca ggagctggat ttggagcacc agaaaatgtc cgcctcagct atgcgacaga
     7501 cctagacacg cttaaagaag cagtcgaacg cttgaaagca tttatgggta gtgagaatga
     7561 ttgatcattt tgagattaag gtaaaggatt tacaaatttc agaaggattt tataggagtt
     7621 ttctcgctcc tttggactat aaattggctt ttaagactag ttctctaatt agttttctat
     7681 ccccgaacag ccctcatcct ggtggtgatt tttggctgac tcagggaaca caagatcctg
     7741 ttcattttgc ttttttagca gaaaataagg aagaagttca ggcttgttat gaggctggct
     7801 tagaggcagg tgggcgagac aatggggctc ctggttatcg aagtgagcat ccgatttact
     7861 atgctgcttt tatgattgac ctggatggga acaatataga ggtggtttgc cataaagaat
     7921 aaaaaagaaa aggaaaaata atgacaaaac gtgtaacgat tattgacgta aaagactatg
     7981 ttggtcagga agtgacgatt ggcgcttggg ttgccaacaa atcaggaaaa gggaaaatcg
     8041 ctttcttaca attgcgtgat ggaacagcct tctttcaagg tgtggctttt aaaccaaact
     8101 ttgtcgaaaa atttggtgaa gaagtgggac ttgagaagtt tgatgttatc aaacgcttga
     8161 gccaagaaac gtctgtttat gtgacaggta ttgtcaaaga ggacgaacgt tctaaatttg
     8221 gctatgagtt ggacatcaca gacatcgaag tgatcggtga atctcaagac tacccaatca
     8281 caccaaaaga acacggaaca gactttttga tggataaccg tcacttgtgg ctacgctctc
     8341 gtaagcaagt agctgtgttg caaatccgta acgctattat ctatgcaact tatgagttct
     8401 ttgacaagaa cggttttatg aagtttgaca gcccaattct ttcaggaaat gcggcagaag
     8461 attctacaga actctttgaa actgactact tcggaacgcc agcctacttg agccaatcag
     8521 gtcaacttta cctagaagca ggggctatgg ctcttggtcg tgtctttgac tttggtccag
     8581 ttttccgtgc tgaaaaatca aaaacacgcc gtcacttgac tgagttctgg atgatggatg
     8641 ctgagtactc atacttgaca catgatgagt cgcttgactt gcaagaagct tatgtgaaag
     8701 ctcttctaca aggtgttctt gaccgcgcgc ctcaagcctt ggaaaccttg gaacgtgata
     8761 cagaactctt gaaacgctac attgcagagc cattcaaacg tatcacttac gatcaagcca
     8821 ttgacctctt gcaagagcat gaaaatgatg aagatgctga ctacgagcat cttgagcatg
     8881 gtgatgactt tgggtcacca cacgaaactt ggatttcaaa ccactttggt gtgccaacat
     8941 ttgtcatgaa ctatccagca gccatcaagg ccttctacat gaaaccagtt cctggaaatc
     9001 cagagcgcgt gctttgtgca gacttgcttg ctccagaagg ctatggagaa attatcggtg
     9061 ggtctatgcg tgaggaagat tacgatgccc ttgtcgctaa gatggatgaa cttggcatgg
     9121 atcgtacaga atatgaattc taccttgacc ttcgtaaata cggtacagtt ccacacggag
     9181 gatttggtat cggtatcgaa cgtatggtaa ccttcgcagc aggaacaaaa catatccgtg
     9241 aagctattcc attcccacgt atgttgcacc gtatcaaacc ataagaacag gaaaacgccc
     9301 atgtggcgtt ttttcgaatt ctagtgtttt tacttgcgta aaaaaaattt ttctagtata
     9361 atagtttatt gtgagcgaac ctcacttacc ccttgcaaag tcttggggtc attagaccaa
     9421 aaggaggaac atatcaatgg ctaaatacga aattctttat atcattcgtc caaacattga
     9481 agaagaagct aaaaacgctt tggtagcacg ttttgactct attttgactg acaacggtgc
     9541 aactgttgtt gaatcaaaaa cttgggaaaa acgtcgtctt gcatacgaaa tccaagattt
     9601 ccgtgaagga ctttaccaca tcgttaacgt tgaagcaaat gacgatgcag ctcttaaaga
     9661 gtttgaccgt ctttcaaaaa tcaacgctga cattcttcgt cacatgatcg tcaaaattga
     9721 cgcgtaagaa ggtaaactat gattaacaat gttgtacttg tagggcgtat gacacgtgac
     9781 gctgaattgc gttatacccc atcaaatgta gcagttgcga cttttactct tgcagtaaac
     9841 cgtacattta agagtcaaaa tggtgaacgt gaggctgatt ttatcaatgt cgttatgtgg
     9901 cgccaacagg ctgaaaatct tgctaactgg gctaaaaaag gctcacttat cggggtgaca
     9961 ggtcgtatcc agactcgtag ttacgataac cagcaaggac aacgtgtcta cgtgacagag
    10021 gtcgtggctg agaatttcca aatgttggaa agccgtagtg tgcgtgaggg tcacacaggt
    10081 ggagcttact ctgcaccaac tgcaaactat tcagcaccta caaattcagt accagacttt
    10141 tcacgtaatg aaaatccatt tggagcaaca aacccattgg atatttcaga tgatgattta
    10201 ccattctaat ggacaactaa acttataaag gagaaaaaac atggctcaac aacgtcgtgg
    10261 cggattcaaa cgccgtaaaa aagttgatta catcgcagca aacaaaattg aatatgttga
    10321 ttacaaagat actgagcttc ttagccgttt cgtttcagaa cgtgggaaaa tccttcctcg
    10381 tcgtgtaaca ggaacttcag ctaaaaacca acgtaaagta acaacagcta tcaaacgcgc
    10441 tcgcgtaatg gctttgatgc ctttcgtaaa cgaagattaa agaaaagacc cggttgggtc
    10501 tctttttcat gaacttgaaa acaagaaagc gaattaagac cccaacgggt cttttttcac
    10561 aagctttgaa atgagagagc gagttaggct cagtggctcc ctttttacga gtttgaaaac
    10621 aagagaacac attaaaagca cgatggagct ttttcataaa tatgtctttt ttttcatcca
    10681 agaaattaaa ataaaaatga taaacttttt gaaaataggg gatttgccta ctttatgata
    10741 taatggaaag agttagattg aaagaggtag tgagatggac gcgaaattaa gatacaaggc
    10801 aaagaagatc aagattgtct tttttgatat tgatgataca ttgcggaatt caaagacagg
    10861 gtttattcca actacaattc ccactgtttt taaacagttg cgtgaaaaag gaattttaac
    10921 aggaatcgcc tctggacgtg gcatttttgg tgttgttcca gagattcgtg atctcaaacc
    10981 tgactttttt gtaactttga atggggctta tatcgaagat aaaaaaggtc aggtcattta
    11041 tcagcatcag attgaaaagt catatgttga ggagtatatc tcttgggcta agcaagaagg
    11101 aattgagtat ggcttggttg ggagtcatga tgccaagttg tcgactcgca ccgatatgat
    11161 gagtgaagct atcaatccaa tttatcccga cttagatgta gatcccgatt tccatgaaaa
    11221 agaagatatc tatcagatgt ggacttttga agataaggga gatgacttgc acttgcctga
    11281 cagtctctca gacaaacttc gcatggttcg ttggcatcaa cattcgtctg atattgtgcc
    11341 gatttcaggc tccaaagcga cgggggtgga aaaggttgtg gaacaccttg gcttgaaacc
    11401 agagaaggtc atggtttttg gagatggtct caatgacttg gaactctttg attatgctgg
    11461 aatcagcgtt gccatgggaa tttctcatga taaaatcaaa gaaaaagcag attatattac
    11521 aaaaacatta gaagaagatg gcatttttga tgccttagaa gtatttggta tggtagaaaa
    11581 agaattgcat tttccacaag tagacattga aacagtagaa ggtcctcttg cgactattaa
    11641 gaccaatcac ggagacttac gtatcaagct tttccctgaa catgctccta aaacagtggc
    11701 taactttgta tctctttcaa aagatggcta ctatgatggt gtcattttcc accgtattat
    11761 caaggacttt atgatccaag gtggagaccc aactggaact ggtatgggtg gcgagtcaat
    11821 ctacggcgaa tcttttgagg atgaattctc agaagagctt tacaatatcc gtggtgctct
    11881 ttccatggca aatgctggtc caaataccaa cggcagccag ttctttatcg tgcaaaacca
    11941 acacctacct tattctaaga aagaaattac tcgtggtggt tggccagaac cgattgcaga
    12001 aatctatgcc aatcaaggtg ggacacctca cctagaccgc cgtcacacgg tttttggtca
    12061 gttagctgat gaagcatctt acgctgtctt ggatgtcatt gctgctgttg agacaggagc
    12121 tatggacaag ccagttgaag atgttgtaat tgaaactatt gaaatcgagg actaagatga
    12181 aaatcggtga taagctaaag gggcgtatta cagggattca gccctacggt gcctttgttg
    12241 agttagagac gggtgatacg gggctgattc acatttcaga aattcggaca ggatttattg
    12301 aaaatattca tgaaaccttg aaagtcgatg aagaggttca agttcaggta gtggatttag
    12361 atgaatttac ggggaaagcc agtctttcta tccgcacttt ggaggaagaa aagtaccagt
    12421 ttcctagacg gagacgcttt tcaagcgacc gctttaacta cggttttgct ccctttcgac
    12481 gaatgctacc aatctggact ggagaagccc tgcaccattt aaaaaagaag aagtagttta
    12541 gagttttata ttttttgtaa tgttaatata aatttgctat aataggacca tggaagaaga
    12601 acaattatta aaatcaggag agcgcattaa ccagctcttt tcgacagata tcaaaatcat
    12661 tcaaaataga gaggttttta gctattcggt ggatagtgtt ctcttatcac gatttccacg
    12721 ttttcctaag aaggggttga ttgtggattt ctgtgctggg aatggagcag tggggctttt
    12781 tgctagcact cgtactcaag cacagatatt gtctgttgag attcaggagc gtttggcgga
    12841 tatggctgaa cgctctgtcc gtttgaatgg attagaggag caaatgcagg tcatctgcga
    12901 tgatttgaaa aatatgcctg ctcacattca ggggagtaag gtggatatga ttttgtgtaa
    12961 tccaccctat ttcaaggtgg atccttattc taatctgaac gagagtgaac attatctctt
    13021 ggctcgacac gaaatcacga ctaatttgga agaaatctgt catagtgccc agagtattct
    13081 caagtctaat gggcgtttgg ccatggttca tcgtcctgat cgacttctgg atattttgga
    13141 tacgttaaaa cgacataatc tagcccctaa gcgcctgcag tttgtttatc caaaaagaga
    13201 aaaggaagcc aatatgcttt tgattgaggc gatcaaggat ggctcaacaa gtggctttaa
    13261 ggtcttacct cctttgattg tccacaatga tgatggctct tatacgcccg aaatcgaaga
    13321 gatttattat ggatcataag gcttatatgt acgttctgga gtgtcgtgat ggatcctact
    13381 atataggcta tacgactgat atgagaagac gcctcgctat ccacaatagt gggaagggag
    13441 ccaaatatac acgagcacgc ttgccagtca aacttatcta tgctcaaggt tttgccagta
    13501 aggaagaagc catgtcggct gaagctcttt tcaagcgtaa gaagaggcca cagaaggaag
    13561 aatttttatc tgaaaatcaa gatagaaatt tactcagtta ttttgaagaa tcgtggggag
    13621 tcctttgact cctcttacct ttgtcaaaaa gcgaaaaaaa tgctacaata aagaaaataa
    13681 acaaaatgag gtattatcat gtccaagatt ctagtatttg gtcaccaaaa tccagactca
    13741 gatgccatcg ggtcatctgt agcttttgcc taccttgcaa aagaagctta cggtttggat
    13801 acggaagctg ttgcccttgg aactccaaat gaagaaacag cctttgtctt gaactatttt
    13861 ggtgtggaag caccacgtgt tatcacttct gccaaagcag agggggcaga gcaagttatc
    13921 ttgactgacc acaatgaatt ccaacaatct gtatcagata tcgctgaagt agaagtttac
    13981 ggtgttgtag accaccaccg tgtggctaac tttgaaactg caagcccact ttacatgcgt
    14041 ttggagccag ttggatcagc gtcttcaatc gtttaccgta tgttcaaaga acatggtgta
    14101 gctgtgccta aagagattgc aggtttgatg ctttcaggtt tgatttcaga tacccttctt
    14161 ttgaaatcac caacaacaca cccaacagat aaaatcattg ctcctgaatt ggctgaattg
    14221 gctggtgtaa acttggaaga atatggtttg gcaatgttga aagctggtac caacttggct
    14281 agcaaatctg ctgaagaatt gattgacatc gatgctaaga cttttgaact caacggaaat
    14341 aatgtccgtg ttgcccaagt gaacacagtt gacatcgctg aagttttgga acgccaagca
    14401 gaaattgaag ctgcaatgca agctgccaac gaatcaaacg gctactctga ctttgtcttg
    14461 atgattacag atatcgtcaa ctcaaactca gaaatattgg ctcttggtgc caatatggac
    14521 aaggtcgaag cggctttcaa tttcaaactt gaaaacaatc atgccttcct tgctggtgcc
    14581 gtttcacgta agaaacaagt ggtacctcaa ttaactgaaa gctttaatgc gtaagatttt
    14641 gggtgtcagc tcaaaatcgg aaagtctagt ttgccttata tcgaaaggag tttcggctcc
    14701 tttttttcta ggagtgaagt atgttagaaa atggcgattt gatttttgtg agagatgggt
    14761 cagacatggg acaggccatc cagacttcca caggtaacta tagccatgtt gccatttatt
    14821 tggatgggat gatttatcat gctagtggac aggctggtgc tgtctgtcaa gaaccggcag
    14881 acttctttga gtccaatcat ttgtacgacc tctatgttta cccagaaatg gatatccagt
    14941 cggtgaagga aagagcttgc agacatcttg gagcacccta caatgcttct ttctatccag
    15001 atgcagctgg tttctactgc tcccagtata tagcagaaat cctacctatt tttgaaacta
    15061 ttcctatgaa atttggagat ggggaacagg agattagtga tttttggagg gagtattaca
    15121 tagaactagg tctgcctgtt cctctgaacc aagctgggac caatcctagt cagttggcag
    15181 catcgcctct gttacaatgt aaagaaagga atcttcatga ttcagatttt taattcatct
    15241 cgtttgacga gacagccatt tttggagaat tgatccgcta tctggaccag tatgaggatg
    15301 tgattctacg ggaaattaag gctcaatttc cagatgttgc agttgataaa ctcatggaag
    15361 agtatataaa ggcaagcttg attctacgtg aaaataagcg ctattacctc aattttccta
    15421 cgcttgaatc acttgatagt cttgaactgg atcaagagat ttttgtcaga gaagctagtc
    15481 cggtctatca agccttgttg gagcagagtt ttgagacgga attgcgcaat caaatcaatg
    15541 cagctatttt agttgaaaga cggactttgc gcgcattaaa atgaccctgt ccaattattt
    15601 ttacaaggtc aaacagcagt atcctttgac agaaaaacag caggagctct atgacatttt
    15661 aggagatgtt aatcctgagt atgcactcaa gtatatgacg gcttttttgt tgaaatttct
    15721 caaaaaagac cagcttatgc agaaatgccg tgatatcttt gtggacagtt tggttgtctt
    15781 aggctatatt gtgcaaaatg aagatagaaa gtatgagttg gctatcgatt ttgataagga
    15841 gagattaact ttctacttag cgtgatttct tgtttctgag cacattgttt gactttcctt
    15901 agtattcggt ataaactata tgtaaccggt aacacatatc ggaataaact aaaggagaca
    15961 atcatatgtc acttgaaaac aaattggaac aagcaacagg cgctgtcaaa gaaggttttg
    16021 gtaaagttac tggagacagc aagacagaac ttgaaggagc tgttgaaaaa acagttgcta
    16081 aggcaaaaga cgttgtagaa gacgcaaaag gtgctgtaga aggtgccgtt gaaggtttga
    16141 aaaacgtttt tactaaataa taggaaaaaa tcaagggttt cattttccct tgattttttc
    16201 tattcttata aataattttc tgcgacggct gtatctcctg ggtaggattc tttcttgccc
    16261 tggatgattt ggtaacaatc ggctccctta cccgcaataa taactgcatc taattcgtga
    16321 tttgtgatag ccattgccgc cttgatggct tcttggcgat ccgcaatctt ttcaacagga
    16381 tgattgatgt agctactaat ttcatctgca atggccattg ggtcttcata gttagggtca
    16441 tcagcagtca gaaagacttg aatctcaggg tgttgattga ggaggaggcc aaagtcctta
    16501 cgacgacttt ctcccttgtt tcctgttgat cccagaacca gagcaatctt tccggtttga
    16561 tgagtttcaa ccacattgat gagttttttc agactatccc cattgtgggc atagtcgatg
    16621 aagaccttgg ctccattttt ctgagtgagg acttccatac gaccaggaac gcgggttgca
    16681 gcgatgcctt ttttgatgtc ctcaagactt gctccgagac ggagacaagc aagtccagca
    16741 gcaactgcat tttcttggtt gaagttgcca atgagttgga tatcataatc tccagcgagt
    16801 ttacccgtag ctgaaaagct aaaggctttg gaattctcga tttggttatc aaattggcta
    16861 ccatagaaat catggtcttg atcttcaacc tgttctttca agactgagaa gtggtccatg
    16921 tcactgttaa tgatgactgc tcggctattt tccatcaaga gacgcttgtg gtagaaatag
    16981 tcttcaaagc tagggtgttc aatcgggccg atatggtcag gagtgatgtt aagaaagact
    17041 cctacatcaa aggtcagtcc atagactcga tggactagat aggcttgact ggagacttcc
    17101 atgatgaggt gggtacggtc attttgcaca gcctgattca tcatgtcaaa gaggtcaata
    17161 ctctcagggg ttgtcaacgc tgacttaaag aaagtctcgc catcaagagt tgtgttcatg
    17221 gtcgacaaca tagcaggtct atgcccttga gataagatgt tataggcgaa ataggttgct
    17281 gttgtcttac ccttagtacc agtaaaggca aggagtttga gtttctcttg tggattacca
    17341 tagaactcca tggcaatcaa actcatggct ttctttatat cgttcacaat gatgacaggg
    17401 atatcgactt cgtagtcctt ttcagctaca taccaagcta aaccttgtgt tatagcagaa
    17461 agaaggtatt cttttttaaa ggcagcgcct tttgcaaaaa aaagagtgtc ttctgttact
    17521 tttcggctgt cgtagctgat gctatcaaaa ataactttgc tgtagttgta gtggtaatga
    17581 ccttggtcaa taatttcgcg aaaaaggcca tctttcttta aaatatctaa tacggtttca
    17641 atcttaatca tactttctat tgtaaaccga aagtcgtaaa tttacaagta acaaggaaaa
    17701 gtttataatg gaagataagg agtttttcct agttatcaaa attgaatgag gaatctatgt
    17761 cgcacgaaaa caatcaccag caggcccaga tgttacgggg gactgcttgg ctaacggcta
    17821 gtaactttat cagtcgccta ctcggggctg tttacattat cccttggtac atctggatgg
    17881 gggcttatgc agctaaggca aatggtctct ttaccatggg ttacaatatc tatgcttggt
    17941 tcttgttggt ttcaacagcg gggattccag ttgcggtggc caagcaagtt gccaagtata
    18001 ataccatgcg agaagaagag catagctttg ccctgattcg gagcttctta ggctttatga
    18061 caggactagg cctggttttt gctttagtct tgtatgtctt tgctccttgg ctagcagact
    18121 tgtctggcgt gggcaaagac ttgatcccaa tcatgcaaag cttggcttgg ggagtcttga
    18181 ttttcccgtc tatgagtgtt atccgaggat ttttccaagg gatgaataac ctcaaaccct
    18241 atgccatgag ccaaattgct gagcaggtca ttcgtgttat ctggatgctc ctagcaacct
    18301 ttatcattat gaagctcggt tcaggagatt atctagcagc cgttacccaa tcaacctttg
    18361 ctgcctttgt cggtatggta gccagttttg cagtcttgat ttatttcctt gcccaagaag
    18421 gttcactcaa aagagtcttt gaaacaggag ataagattaa cagtaagcgt ctcttggttg
    18481 ataccattaa ggaagccatt ccttttatcc tgacagggtc tgccatccag ctcttccaga
    18541 ttttggatca gctgaccttt atcaatagta tgagctggtt taccaactac agcaatgagg
    18601 acttggttgt catgttttct tatttctcag ccaatcctaa taaaatcacg atgattttga
    18661 tttctgtagg ggtttcgatt gggagtgttg gtttgccact tttgacggaa aactatgtca
    18721 agggggactt gaaagcagct tctcgtctcg ttcaggacag tctcacccta ctctttatgt
    18781 tcttgctacc agcaacggtt ggagtggtta tggtaggaga acctctttat acggtcttct
    18841 atggtaagcc agatagtttg gctctgggct tatttgtctt tgcagttttg cagtctatta
    18901 ttttaggctt gtacatggtc ttgtctccaa tgcttcaggc catgttccgc aaccgcaagg
    18961 ccgttctcta ttttatctat ggttctattg ccaagctagt cttgcaacta cctaccatcg
    19021 ccctcttcca cagttatggt cctttgattt caacaaccat tgctctcatc attcctaacg
    19081 tcttgatgta tcgggatatt tgtaaagtaa ctggtgtcaa gcgcaaggtg attttgaagc
    19141 gaaccatttt aatcagtttg ctgaccctag tcatgtttct gttaatagga accatccagt
    19201 ggctgttagg atttttcttc caaccaagtg gacgtttgtg gagcttcttt tatgtagctc
    19261 ttgtcggtgc catggggggt ggactttata tggttatgag tctgcgtacc tatttattag
    19321 ataaggtaat aggaaaagcc caagcagatc gcctgcgagc aaaatttaag ctttcgtaag
    19381 gtagcattta taaataaaag gaataagttg aacaatcttt taggagaact tgaagcttat
    19441 tcctttttta gcgtaaaaat agctaaaatt atatttcaaa aatagaaaat gaggcttttt
    19501 tcgatttttt ggaaaaaatc attgactaaa caaactaaac gttgtataat aaaacaaata
    19561 tttaaagcag gaggttccgg aaatgaaaaa gtctaagagc aaatatctaa ccttggcagg
    19621 tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga aattctagca cggcgtcaaa
    19681 aacatacaac tatgtttatt caagtgatcc atctagcttg aactatctag cagaaaaccg
    19741 cgcagcaaca tccgatattg ttgcaaattt ggtagacggg ttattagaaa atgaccaata
    19801 tgggaatatt attccatcat tagcagagga ttggactgtt tctcaggacg gtttgaccta
    19861 tacctacaaa cttcgtaagg atgccaagtg gtttacttct gagggagaag aatatgcgcc
    19921 tgtaactgcc caggattttg tgacaggttt gcaatatgca gctgataaaa aatcagaagc
    19981 cttgtatcta gtgcaggact ctgttgctgg tttggatgac tatatcactg gtaaaacaag
    20041 cgacttttca actgtcggtg tcaaggcact tgatgaccaa acggttcaat atactttggt
    20101 taaaccagaa ctttactgga attcaaaaac acttgcaacg atactttttc ctgttaatgc
    20161 agatttcctg aaatcaaaag gggatgattt tgggaaggcg gatccatcta gtattttgta
    20221 caatggacct ttcttgatga aagcacttgt ctcaaaatct gctattgaat ataagaaaaa
    20281 ccctaattac tgggatgcta agaatgtctt tgtagacgat gtgaaattga cctactatga
    20341 tggtagcgac caagaatcac tggaacgtaa ttttacagct ggtgcttata ctacggctcg
    20401 tctttttcct aacagctcca gctatgaagg gattaaagaa aaatacaaaa acaatatcat
    20461 ctatagtatg caaaattcaa cttcatattt ctttaatttt aacctagata ggaagtctta
    20521 caattatact tctaaaacaa gtgacattga aaagaaatcg actcaggaag cagttctcaa
    20581 taaaaacttc cgtcaggcta tcaattttgc ttttgacaga acatcttatg gggctcagtc
    20641 tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta gtggttcctc caaactttgt
    20701 cagtatcaag ggaaaagact ttggtgaagt tgtagcctct aagatggtca actatggtaa
    20761 ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct tactacaatc ctgagaaagc
    20821 caaggctaag tttgcggaag ctaagaaaga actcgaagca aagggtgttc aattcccaat
    20881 ccacttggat aagactgtgg aagtaacaga taaagtaggc atacaaggag ttagttctat
    20941 caaacaatca attgaatctg ttttaggttc tgataatgta gtgattgaca ttcagcaatt
    21001 aacatcagat gagtttgaca gttcaggcta ctttgctcaa acagctgctc agaaagacta
    21061 tgatttatat catggcggtt ggggacctga ttatcaagac ccgtcaacct atctcgatat
    21121 ttttaatact aatagtggag gatttctgca aaatcttgga ctagagcctg gtgaggccaa
    21181 tgacaaggct aaggcagttg gactggatgt ctatactcaa atgttggaag aagctaataa
    21241 agagcaagat ccagccaaac gttatgagaa atatgctgat attcaagctt ggttgattga
    21301 tagttcttta gttcttccaa gtgtttcgcg tgggggaaca ccatcattga gaagaaccgt
    21361 accatttgct actgcctatg gtttaaccgg tacaaaaggg gttgaatcat ataaatacct
    21421 caaagtacaa gataagattg tcacaacaga cgaatatgca aaagccagag aaaaatggtt
    21481 gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa ttggcaaaac atgtcaaata
    21541 aaatctaatt gtagataagt ttgtgtaaga agtctttgtg cttaaaaacg cataatatca
    21601 ggtatataaa atcctagatg ttatgcgttt tgttatagga agatttatta gattttatcc
    21661 tcaaattgag ttattcccga ctttatccgt tgaaatatta taaggagtat ttatgaaatt
    21721 aaaattatta agagtagata ctaaggtgat tatggggagt ttcttacttg ttctgtctag
    21781 tctacttgct ttgttgcttc cccttatctt aaagggttta atagatggga gttctattga
    21841 aaatataggt tccaaagtat ttcaatcgtt tttgattttt attggtcaag ccttgttttc
    21901 ttctattggt tactatctgt ttagtcaatc gggtgaaaaa aagatagcaa aaatcaggaa
    21961 aaaagtgata gaggggttga tttatgcaga gaaatccttc tttgataaga gccaaagtgg
    22021 ggagttgact tctgccattg tcaatgacac gagtgtcatt cgtgagtttt taattacgac
    22081 tttcccaaat attattctga gtttagttat ggtacttggt tccattgtag tcttatttag
    22141 tcttgattgg aatctttctc tacttttatt catcactctt ccttgtatga tgtttattat
    22201 cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt ttacaggagg aaatcggatt
    22261 tttaacaggg caattgactg aaaagattca agaacatgaa ttaattaaga ctaaccaagc
    22321 agagaaaagt gtacaggatg ttttggataa ttgtattgaa agggtacaaa acaattcact
    22381 gaaatcagat agggttactt cttttgagac cccgtttgct ctcttattta tctttgcgac
    22441 tatagctgtg atgctaacct atgggggtta tcgggtcagc gcaggatata tatctgtggg
    22501 aaccttggtt tcgtttttga tttacctctt tcaattactt aatcctatta gtaatatagc
    22561 taattttgta actgtttatt ctaggagcaa gggatcttca gttgcactgg agaacttgct
    22621 tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta tcaggacaag ggttgaattt
    22681 taaccatgtc tattttggtt atgatgaaaa tcgacctgtc ttaaaggata ttacttgttc
    22741 aattttcaag gggcaaaaaa ttgcttttgt tggaccatct ggatcaggaa aatcaacgat
    22801 tgtgcgtttg ttagagcggt tttataaacc gctttcagga gatattctaa tggagcaatc
    22861 aagtatatat gattttaact taaaagaatg gagaagtaaa atcgcttagt aactgatgat
    22921 gaattgatga aagtgctaga cttagtatca ctaggtgatg agattcgctc catgaaagag
    22981 ggactagata ctgaagttgg tgaacgcgga cgactcttgt caggggggca aagccaaaga
    23041 cttcaaatag ctagagccta cttaaaagat gctgaaattc ttatatttga tgaagccact
    23101 gctaatcttg atgcggattc tgagtatgcg attatcagta gcctctattc tgtattaaag
    23161 gagaagacgg ttgtgattat agcgcatcgt ttgtcaacgg taaaagatgt ggattgtatt
    23221 ttcttcttag aggaggggaa aatcactggc tcaggaactc ataaggaact actggaaaat
    23281 catgagcgtt atgctcgttt tgtgcaggag caaatgatag agtgaaggtg tcttttgaga
    23341 ttcaccattt tatagtctat taaagggagc aggaaaaact ccctttttat atagtttgaa
    23401 actataacta gctcttgaaa agaagaaaat gagttgatga aaataagtgg tacaatagtt
    23461 actatagatt tggaggtatt gtatgagcaa ggaattacac attaacacaa ttttggccca
    23521 ggcgggtatt aagtcagatg aagcgacagg tgcattggtg acaccgcttc atttttcaac
    23581 gacctatcag catccagagt ttggtcgatc tactgggttt gactatacgc gcactaaaaa
    23641 tccaactcgt agtaaggctg aggaagtctt ggcggctatt gagtcagcag actatgccct
    23701 agcgactagc tcagggatgt cagctattgt actggccttt agcgtctttc cagtaggaag
    23761 taaggtcttg gcagtgcgtg atctttacgg tggttctttt cgctggttta accaagtgga
    23821 gcaggaaggt cgtttccatt ttacctatgc caatacagaa gaagagttga ttgccgagtt
    23881 agaaaaggat gtggatgttc tctatatcga aaccccaacc aatcccttga tgttggaatt
    23941 tgatatcgaa aaactagcaa aattggctca tgctaagggt gccaaagtgg tggtggacaa
    24001 taccttctat agccctatct accaacgtcc gattgaagat ggagcagata tcgttctcca
    24061 ttcagcaacc aagtatctag caggccacaa tgatgtcttg gctggagtgg ttgtgaccaa
    24121 tagtttagaa ctatacgaga agctttttta caatctcaat acaacagggg cagtcttgtc
    24181 tccatttgac agctaccagt tgcttcgtgg tctcaagacc ttatctcttc gtatggagcg
    24241 ctcaacagct aacgcccaag aagtggttgc ctttttgaag gattctccag cagttaagga
    24301 agttctctac actggtcgtg gaggcatgat ttcctttaaa gtagccgatg aaacacgcat
    24361 tcctcatatt ttgaacagtc tcaaggtctt ctcttttgcg gaaagtttgg gcggagtgga
    24421 aagtcttatt acttatccaa cgactcaaac tcatgctgat attccagcag aagtacgcca
    24481 ttcttatggt ttgacagatg acctcttgcg tttgtctatt gggattgagg atgctagaga
    24541 tttgattgca gatttgcgcc aagccttaga aggataagac aaagatggga aaatatgatt
    24601 ttacaagcct gcccaaccgt ttagggcacc atacctataa atggaaagaa acagaaacgg
    24661 atagtgaagt tctaccagct tggatagcgg atatggactt tgtggtcttg cctgaaatcc
    24721 gccaagccgt gcaaacttac gcagaccaac tggtttatgg ttatacctat gccagtgaag
    24781 acttaattaa ggaaattcaa aagtgggaag ctacacaata cggttacaac tttgacaaag
    24841 aggctcttgt ctttatcgag ggtgtggtac cagccatctc aacagctatt caaaccttta
    24901 caaaagaagg cgaggcggtt ttaattaaca cgcctgtcta cccacccttt gctcgcagtg
    24961 tcaagttgaa taatcgtaga ttgattacta attccttagt ggaaaaggat ggtctgtttg
    25021 agattgactt tgaccaactt gaaaaggatt tggtggaaga ggaggttaaa ctctatattc
    25081 tttgcaaccc tcacaatcct ggtggacgtg tttgggaaaa agaagtgttg gagaagattg
    25141 gccaactttg ccaaaaacac ggtgttttgt tagtttcgga tgagattcac caagatttga
    25201 ccctctttgg tcacaaacac cagtctttca ataccatcaa tcctgccttc aaaaattttg
    25261 ctatcgtctt gagcagtgcc actaaaacat ttaatattgc tggaacaaaa aattcctatg
    25321 cagtcattga aaatcctaag ttgagactgg ctttccagaa acgcctgttg gccaataatc
    25381 agcatgaaat ttcaggcttg ggttatttgg cgacagaagc tgcctatcga tacggtaaag
    25441 attggctaga ggaactcaag caagtctttg aagaccacat caattatgtg gtggatctat
    25501 ttggaaaaga gactaaaatc aaggtcatga aaccgcaagg tacctacttg atttggcttg
    25561 acttttcagc ctatgacctg actgatgaaa cattgcaaga gttgttgaga aatgaagcca
    25621 aggttatcct caaccgtggt ttggattttg gagaggaagg aagtctccat gcccgcatca
    25681 atatagctat gcccaaatct ctgttgcaag aagtctgtca gcggattgtg gctacttttg
    25741 ccaaacgtta aaaatccagc cttctaggag aaaagtcttc ctagaaggct attttcatag
    25801 gcgaaaatat ggtataataa aaagataagg taaaggtgaa aatatggcta aattgattcc
    25861 ggggaaaatt cgtatcgaag gtgttgccct ttatgaaact ggtaaggttg atatcatcaa
    25921 ggaaaagaac aatcggctct acgctcgcgt tgcagaagaa gaactgcgct atagtttaga
    25981 ggatgatttg gttttttgtg cctgtgattc ttttcaaaag aggggctact gtgtgcattt
    26041 ggcagcgcta gagcattttc tgaaaaatga tgagcgtggt caggaaatct tgtggagtct
    26101 ggaagaaggt catgaagaaa aagaggccgt tgaaaccaag gtgaccttgg gtggcaagtt
    26161 tttgaatcga attttatctc caaaatcaga atgcgcctat gagttatcag ctgtgggtca
    26221 ggtggaagca ggaaccaatc atatcttgtg gactctgaga atcggccaaa tcaatagcca
    26281 aaaatactat gtcattcggg atattccact ttttttaagg attgtcgagc agagaaagtc
    26341 gtatatgatt ggcaagattt atgaggagtc tctttcttgg gaagcctttg atgatgccag
    26401 ccaagaactt ttgactttct tgcacggact aacggaggaa gggctggttc cagacctctt
    26461 tttccaaaac caaggtcggc acctcttttt ccctctgacc ttttttgagc agggtgtgaa
    26521 tttactgatg gccttgcccc attttcaatt tgaccatcaa gtggatagct accaaaccct
    26581 gctttttcag gatatgcatg ctgatgccaa tctatttgcc tttacagtaa cagaatactc
    26641 ggactatttt gaaatggaaa tcagtgagag tcctagggtc aatgtctttt atcagggagc
    26701 agtacttttc cataaaggtc aggtttattt tttaacagac cagcagatgc gtcttctcaa
    26761 ggaaattaaa gcgttacctg tgggtcaaca aggaaagaaa tacctgcaat ttgatagcag
    26821 tgatcgagac aaattggcct cctgtctgac tctttttatc cagatgggca ccgtttcagc
    26881 tccagaacgt ctacaaatca aaacttttgc gccctctttt tactttgaca gggaagaaga
    26941 taatcggatt cgtttagaaa ttcagtttga ttatggaaat agacaggtat ctagccgaca
    27001 agagctagaa gaattaccat tttcaagtga cgcggactta gaagaaagaa ttttccaagt
    27061 ctgtttggct gcgggctttg aagccgattt tcaatcttgg cgtcaggcct taaaagcgga
    27121 gtctgtctat catttttttc atgatatcat tccagtcttt gaaaaactcg ggcatgttga
    27181 cctatcagat aaactagaag agctttatag cctagcgagt cctcaggtgc agattgcctc
    27241 caagggaggt ctcttggaaa tccagtttga ttttcaaaat attgcccagg aggaaatcga
    27301 ccaagccatg caggccttgg ttgccaatca ggatttttat attgattcgt ctaatcaagt
    27361 ttactttttc gatgaagaaa ccaagaaaat tcgccaaaat ctacaggaac tggggcaatt
    27421 tgaattaaaa gatgggacct tgcaggctcg gaaatccttg gcctacagtt tagctcatct
    27481 ctttgaaggg cgagaccgtg tttctttttc acaagaattc cagaatctgg cccaggattt
    27541 gacgcatcca gaggactttc ctttgcaagc aactcaggtc aaggctgact tgcgagatta
    27601 tcaggaaaag ggaattggct ggttgcagat gctccatcat tatggttttg gtgggatttt
    27661 ggctgatgat atgggacttg ggaaaaccct tcagaccatt gcttttttga ctagtcaagt
    27721 gacaaaagaa agtcgagtct tgattctcgc tccgtcgggt ttgatttaca actgggcgga
    27781 tgagtttcag aaatttgccc cacagttgga tgtggctgtt gttcatggtt tgaaagcaag
    27841 tcgtgaggag attcttgccg agagccatca aatctatgtg actagctatg ccaccttccg
    27901 tcaggacagt gagttttatc aggggatggc ctttgacttc cttttcttag atgaggctca
    27961 ggtcatgaaa aatgcccaga ccaagattgc ccagaccttg agacaatttg tggtgccgtc
    28021 ggtctttgcc ttgtcaggaa ctccgattga aaaccatctg ggtgagttgt ggtctatttt
    28081 ccaaatcgtc atgcccggac ttttgccaag caagaaagaa tttatgaaat tgccagcaga
    28141 gcgagtggct cagtttatca agcctttcgt gatgcgacgc aagaaagaag aagttctgac
    28201 tgaattgcca gacttgattg aggtggttta taaaaatgaa ctggaagacc agcaaaaggc
    28261 tatttacctt gcccagttac aacagatgcg agaccatctg gctcaagtgt cagaacagga
    28321 atttcagcga agtcgtgtgg aaattttatc tggtttgatg cgcttgcgtc aaatatgtga
    28381 cactcctgcc ctgtttatgg aagattatca gggagccagc ggcaaactag atagtctccg
    28441 agacctactg gtacaggtgg cagacggcgg acaccgtgtc ttgattttct ctcagttcaa
    28501 gggaatgttg gaaaaaattg aacaagaact gccagacttg ggcctgactt cctttaaaat
    28561 tacgggttca accccagcca aggaaagaca agacatgacc aaggccttta atcaaggaga
    28621 aagagatgcc tttctgattt ccctcaaggc tggtggggtc ggtctgaacc tgacaggtgc
    28681 agatacagtg atcttggttg acctttggtg gaatcctgcg gtggaagcgc aagccattgg
    28741 ccgtgcccat cggatgggtc aggaagaaac ggttgaggtc tatcgcttgg tgaccaaggg
    28801 aaccattgaa gaaaaaattc aggaactcca agaacaaaag aaacatctgg tgtcacaagt
    28861 attggacggc acagagtcac gtggtagtct gaccctagca gaaattagag aaattttggg
    28921 aatttctgaa gccagcactt gaaaaatcaa gacaatacgc tataatgaag tgttgaaagg
    28981 aaatagaaaa tgaaacaaga acgatttcca ttggtgtcag atgacgaggt catgttgact
    29041 gaaatgccag tcatgaatct ctatgatgag tctgatctga tcagtaatat caagggtgag
    29101 tatcgagata aaaattattt agaatgggct cctattgctg aagaaaaacc agtaaaaccg
    29161 attgaaaagc aagtagggaa acctaaaaaa gctcctttag gggttaaaaa agaaggaaag
    29221 agctatgcgg aggtggcgcg tgaagaagcg cgtgcagact tgaaaaagaa acgctctgct
    29281 aactatctaa ctcaggattt cagccttgcg agacgtcatt ctcagcccag tctagttaga
    29341 cagggcaatc aaccgacaac tcctttccaa aaggaaaatc ctggtgaatt tgtcaaatat
    29401 agccaaaaat tgacccagtc tcattatatc ttggcggaag aagttcattc tatccctacc
    29461 aagaatgaag aagtgtcagc acctgctcca aagaaaaaca attatgattt tctaaagaag
    29521 agccaaatct acaataaaaa aagtaaacaa acagaacaag aacgtcgggt tgcccaagag
    29581 ttgaatctga ccagaatgac agaataggga gaaaacatgt caaagacata tcattttatc
    29641 ggaattaagg gatcagggat gagtgccttg gccttgatgt tgcaccagat ggggcacaag
    29701 gttcagggat cagatgttga aaagtactac tttacccaac gcggtcttga gcaggcagga
    29761 attaccattc ttccttttga tgaaaagaat ctagacggtg atatggaaat tatcgctgga
    29821 aatgcctttc gtccagataa caacgtcgaa attgcctatg cggaccaaaa tggtatcagc
    29881 tacaaacgtt accatgagtt tctaggtagc tttatgcgtg actttgttag catgggagta
    29941 gcaggagcac atggaaaaac ttcaacgaca ggtatgttgt ctcatgtctt gtctcacatt
    30001 acagatacca gcttcttgat tggagatggg acaggtcgtg gttcggccaa tgccaaatat
    30061 tttgtctttg aatctgacga atatgagcgt cacttcatgc cttaccaccc agaatactct
    30121 attatcacca acattgactt tgaccatcca gattatttca caagtctcga ggatgttttc
    30181 aatgccttta acgactatgc caaacaaatc accaagggtc tttttgtcta tggtgaagat
    30241 gctgaattgc gtaagattac gtctgatgca ccaatttatt attatggttt tgaagctgaa
    30301 ggcaatgact ttgtagctag tgatcttctt cgttcaacaa ctggttcaac cttcaccgtt
    30361 catttccgtg gacaaaactt ggggcaattc cacattccaa cctttggtcg tcacaatatc
    30421 atgaatgcga cagccgttat tggtcttctt tacacagcag gatttgattt gaacttggtg
    30481 cgtgagcact tgaaaacatt ttccggtgtt aaacgtcgtt tcactgagaa aattgtcaat
    30541 gatacagtga ttatcgatga ctttgcccat catccaacag aaattattgc gaccttggat
    30601 gcggctcgtc agaaataccc aagcaaggaa attgtagcag tctttcaacc gcataccttt
    30661 acaagaacca ttgccttgtt ggacgacttt gcccatgctt taaaccaagc agatgctgtt
    30721 tatctagcgc aaatttatgg ctcggctcgt gaagtagatc atggtgacgt taaggtagaa
    30781 gacctagcca acaaaatcaa caaaaaacac caagtgatta ctgttgaaaa tgtttctccg
    30841 ctcctagacc atgacaatgc tgtttacgtc tttatgggag caggagacat ccaaacctat
    30901 gaatactcat ttgagcgtct cttgtctaac ttgacaagca atgttcaata ggatgttccc
    30961 atggaaattc caattaagat cattcaggca agcaagtctg atttgcctga gataggggca
    31021 cttcagacct cgtcttttcc agctgaaaag cagcaacttt cccatatttt agaagaaagt
    31081 atccgtaagt gtgcggatac ctttcttcta gctagggatg aaaatcaact tttaggctat
    31141 attttatcaa gtccccagtc agacaatccg caatatctaa aagtacattc tttagtcatc
    31201 gagtctgacc atcagagaca gggcttggga acacttcttc ttgcagcctt gaaagaggtg
    31261 gcagttgatc tggattacaa agggattcgt ttggagagtc ctgatgagct gctttcctat
    31321 tttgaaatga acggttttgt tgatgaagaa gcaactttgc tctatgcaac tagccagggc
    31381 tatagtatga tttggtttaa tcccttttat ctggaggaac aatgaaaatc agacaagcaa
    31441 gattagaaga tttggatcgg attgttgaac ttgaatttga aaatttttcg gtcgaagaag
    31501 ccattcctcc ttctgtcttt gaagcacatt tgagagaaat tcagacctct tttctggttg
    31561 ctgaaaaaga aggaagaatc atgggttata tcgaaggacc agttggcctg caccgccatc
    31621 tgcaagacca gtcttttaca gaagaaataa aagactatag tcatgagcct ggtggttata
    31681 tctctgtgac ctgtctgtct attgccaagg aggcacaggg actcggactg ggtcagaaat
    31741 tgctgacagc tttgaaagaa gttgctcttg aagatgagag agatggcatt aatctaacct
    31801 gtcatgacta tctcatcgcc tattatgaaa aacatggatt tgtcaacgaa ggccagtccc
    31861 agtcaacctt tgcaggggaa acatggtatg atatggtctg ggaaatgaaa aaataagtta
    31921 ggaaaagtat catagattgc tttttttgga cttttaagat ataatattat ggattatcaa
    31981 caaggaggaa aaacttttga gtgaaaagtc aagagaagaa gagaaattaa gctttaaaga
    32041 gcagattctg agagatttag aaaaagtaaa aggctatgat gaagttctga aagaagatga
    32101 ggcagtagtt cgcactcctg caaatgaacc ttcagctgaa gaactcatga ctgattcctt
    32161 gtcaacggta gaggagatta tgagaaaagc tcctaccgtg cctactcacc caagtcaagg
    32221 tgtaccagct tctccagcag atgagattca aagagaaact cctggtgttc caagtcatcc
    32281 aagtcaagat gtaccttctt ctccagcgga agaaagtgga tcaagaccag gtcctgttag
    32341 acctaagaaa cttgaaagag aatacaatga aaccccaaca agggtagctg tttcctatac
    32401 gacggcagag aaaaaagcag aacaagcagg tccagaaaca cctacgcctg ctacagaaac
    32461 agtggatatc atcagcgata catcacgtcg tagccgtaga gaaggagcaa aacccgttaa
    32521 tcctaagaaa gagaagaagt cacatgtgaa agcttttgtg atttcattcc ttgtattcct
    32581 tgccttgctc tcagcaggtg gttactttgg ttaccagtac gtgctagatt ctttgttacc
    32641 tatcgatgct aattctaaga aatatgtgac ggttggaatt ccagaaggtt caaacgttca
    32701 agaaatcggt acgacgcttg aaaaagctgg tttggtaaag catggtctga tttttagttt
    32761 ttatgccaag tataaaaatt ataccgactt gaaagcaggt tactacaatt tgcaaaagag
    32821 tatgagtaca gaagacttac tcaaagagtt gcaaaaaggt ggaacagatg aaccgcaaga
    32881 acctgtactt gcgactttga caattccaga aggttatacc ttggatcaga ttgctcaagc
    32941 tgtgggtcaa ttgcaaggtg acttcaaaga gtctttgaca gcggaggctt tcttggctaa
    33001 agttcaagat gagacgttta tcagtcaagc agtagcgaaa tatcctactt tactggaaag
    33061 tttgcctgta aaagacagcg gtgcgcgtta tcgtttggaa ggataccttt tcccagctac
    33121 atactctatc aaggaaagca caactattga gagcttgatt gatgagatgt tagctgctat
    33181 ggataagaac ctatctcctt actatagtac tatcaaatct aaaaatttga ctgtcaatga
    33241 gttgttgacc attgcttcct tggtcgaaaa agaaggtgcc aagacagaag atcgtaagct
    33301 cattgcaggt gtattctaca atcgtttaaa tcgtgatatg ccacttcaaa gtaatattgc
    33361 aatcttgtat gcccaaggaa aactggggca aaatatcagt ctagctgagg atgttgcgat
    33421 tgataccaac attgattcac cttataatgt ttataaaaat gtaggtctca tgcctggtcc
    33481 agtcgatagt ccaagtctgg atgcgattga gtcaagcatc aatcaaacta agagcgataa
    33541 cctctacttt gtagcagatg tcacagaagg caaggtctac tatgctaaca atcaagaaga
    33601 ccacgaccgc aatgtcgctg aacatgtcaa cagcaaatta aactaaacaa actaaaatta
    33661 tgtgatacgt cacataattt tctttagaaa atattatcag aagaaagttg agaaaaatgg
    33721 cagaaaaaac atatcctatg acccttgagg aaaaggaaaa acttgaaaaa gaattagaag
    33781 aattgaaatt ggttcgtcga ccagaagtgg tagaacgcat taagattgcc cgttcatacg
    33841 gtgacctttc agaaaacagt gagtacgaag cagctaagga tgaacaagcc tttgtcgaag
    33901 gacaaatctc tagcttagaa acaaaaatcc gctatgctga aatcgtcaat agcgacgcag
    33961 ttgcccagga cgaagtagcg attggtaaaa cagtcaccat ccaagaaatt ggtgaggacg
    34021 aagaagaagt ttatattatc gtaggttcag ctggtgcgga tgcctttgca ggtaaggttt
    34081 caaatgaaag cccaattggg caggccttga ttggcaagaa aacaggtgac acagcaacca
    34141 ttgaaacgcc tgttggtagc tatgatgtaa aaatcttgaa ggttgaaaaa acagcctaaa
    34201 aacagaaaaa ggagtgggga ggcgatgtgc ttcactcact cctttttcca ttttgctatt
    34261 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttgcc gtatgtatgg ttactgactt
    34321 tgtcagtttc atctacaacc tcaaaac
//
LOCUS       DAVAZV010000017        33324 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVAZV010000017 DAVAZV010000000
VERSION     DAVAZV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33324
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.017"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..327
                     /locus_tag="VQT46_000817"
     CDS             <1..327
                     /locus_tag="VQT46_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2370870.1"
                     /translation="KPQTEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESEEPQV
                     ETEKVEEKMREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLA
                     LLKESK"
     gene            749..979
                     /locus_tag="VQT46_000818"
     CDS             749..979
                     /locus_tag="VQT46_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HET2370871.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLAFFDLGSAIKC"
     gene            1383..2096
                     /locus_tag="VQT46_000819"
     CDS             1383..2096
                     /locus_tag="VQT46_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET2370872.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            2154..2756
                     /locus_tag="VQT46_000820"
     CDS             2154..2756
                     /locus_tag="VQT46_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370873.1"
                     /translation="MSEVDFNEAVNYEFTSDTCQLANSIYQSLFKFFDKKNFSGDLIF
                     TWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLNMNRNGCMGDFPHDFF
                     DIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSNFDDFLEKNYLKTIWQ
                     VSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            2892..3545
                     /locus_tag="VQT46_000821"
     CDS             2892..3545
                     /locus_tag="VQT46_000821"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET2370874.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            3555..4019
                     /locus_tag="VQT46_000822"
     CDS             3555..4019
                     /locus_tag="VQT46_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET2370875.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            4032..5300
                     /locus_tag="VQT46_000823"
     CDS             4032..5300
                     /locus_tag="VQT46_000823"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET2370876.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            5314..5574
                     /locus_tag="VQT46_000824"
     CDS             5314..5574
                     /locus_tag="VQT46_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370877.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            5585..6946
                     /gene="pdrM"
                     /locus_tag="VQT46_000825"
     CDS             5585..6946
                     /gene="pdrM"
                     /locus_tag="VQT46_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET2370878.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            7100..8068
                     /locus_tag="VQT46_000826"
     CDS             7100..8068
                     /locus_tag="VQT46_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET2370879.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            8084..9076
                     /locus_tag="VQT46_000827"
     CDS             8084..9076
                     /locus_tag="VQT46_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET2370880.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYISEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            9294..10337
                     /locus_tag="VQT46_000828"
     CDS             9294..10337
                     /locus_tag="VQT46_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET2370881.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            10401..12086
                     /gene="lpdA"
                     /locus_tag="VQT46_000829"
     CDS             10401..12086
                     /gene="lpdA"
                     /locus_tag="VQT46_000829"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET2370882.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEIIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMQSPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEIIGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            12150..13139
                     /locus_tag="VQT46_000830"
     CDS             12150..13139
                     /locus_tag="VQT46_000830"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET2370883.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQT46_000831"
     CDS             complement(13206..14276)
                     /gene="xerS"
                     /locus_tag="VQT46_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET2370884.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(14860..16410)
                     /locus_tag="VQT46_000832"
     CDS             complement(14860..16410)
                     /locus_tag="VQT46_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET2370885.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFIIIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGSLVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(16426..17205)
                     /locus_tag="VQT46_000833"
     CDS             complement(16426..17205)
                     /locus_tag="VQT46_000833"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET2370886.1"
                     /translation="MATIKEIKELLVTVKELESPIFLDLEKDNRSGVQKEISKHKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQVVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQT46_000834"
     CDS             complement(17192..18043)
                     /gene="ylqF"
                     /locus_tag="VQT46_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET2370887.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EGLDGND"
     gene            complement(18250..18426)
                     /locus_tag="VQT46_000835"
     CDS             complement(18250..18426)
                     /locus_tag="VQT46_000835"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2370888.1"
                     /translation="MQAGIPTDNEVSYALIYQQETLPATGSSTSALTALGLLAVGSLV
                     LLVHNMTGTVFCSL"
     gene            complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQT46_000836"
     CDS             complement(18478..24369)
                     /gene="iga"
                     /locus_tag="VQT46_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="HET2370889.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGSIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     ETEVQPESPDTVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQEAENPVQPAEESTTNSEKVSPDTSSENTGEVSSNPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEKKLEL
                     RNVSDIELYSQTNGTYRQHVSLDGIPENTDTYFVKVKSSAFKDVYIPVASITEEKRNG
                     QSVYKITAKAEKLQQELENKYVDNFTFYLDKKAKEENTNFTSFSNLVKAINQNPSGTY
                     HLAASLNANEVELGPDERSYIKDTFTGRLIGEKDGKNYAIYNLKKPLFENLSGATVEK
                     LSLKNVAISGKNDIGSLANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESS
                     FKGRIVNTYETTDAYNIGGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLV
                     DQDAHIQNSYAEGDINNVKHFGKVAGVAGYLWDRTSGEEKHAGELTNVLSDVNVTNGN
                     AITGYHYTGMKVANTFSSKANRVFNVTLEKDEVVSKESFEERGTMLDASQIVSKKAEI
                     NPLTLPTVEPLSTSGKKDSDFSKIAHYQANRALVYKNIEKLLPFYNKSTIVKYGNLVK
                     ENSLLYQKELLSAVMMKDDQVITDIVSNKQTANKLLLHYNDHSSEKFDLKYQTDFANL
                     AEYNLGNTGLLYTPNQFLYDRDSIVKEVLPELQKLDYQSDAIRKTLGISPEVKLTELY
                     LEDQFSKTKQNLGDSLKKLLSADAGLASDNSVTRGYLVDKIKNNKEALLLGLTYLERW
                     YNFNYGQVNVKDLVMYHPDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYGISLAS
                     QHGTTDLFSTLEHYRKVFLPNTSNNDWFKSETKAYIVEEKSTIEEVKTKQGLAGTKYS
                     IGVYDRITSATWKYRNMVLPLLTLPERSVFVISTMSSLGFGAYDRYRSSDHKAGKALN
                     DFVEENARETAKRQRDHYDYWYRILDEQSREKLYRTILLYDAYKFGDDTTSGKATAEA
                     KFDSSNPAMKNFFGPVGNKVVHNQHGAYATGDGVYYMSYRMLDKDGAITYTHEMTHDS
                     DQDIYLGGYGRRNGLGPEFFAKGLLQAPDQPSDATITINSILKHSKSDSTEGSRLQVL
                     DPTERFQNAADLQNYVHNMFDLIYMMEYLEGQSIVNKLSVYQKMAALRKIENKYVKDP
                     ADGNEVYATNVVKELTEAEARNLNSFESLIDHNILSAREYQSGDYERNGYYTIKLFAP
                     IYSALSSEKGTPGDLMGRRIAYELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGK
                     ERGLVTDELVLKKVFDGKYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPSYGTK
                     TINNVDELQALMDQAVLKDAEGPRWSNYDPEIDSAVHKLKRAIFKAYLDQTNDFRSSI
                     FENKK"
     gene            complement(24578..25756)
                     /locus_tag="VQT46_000837"
     CDS             complement(24578..25756)
                     /locus_tag="VQT46_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370890.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCRNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLPLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWILNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
     gene            complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQT46_000838"
     CDS             complement(25926..29576)
                     /gene="addA"
                     /locus_tag="VQT46_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET2370891.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWKLAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALVEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQNFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLESKEYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIDEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQIIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTALGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
     gene            complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQT46_000839"
     CDS             complement(29573..32848)
                     /gene="rexB"
                     /locus_tag="VQT46_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET2370892.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPVKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQTTEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWLEKIREE
                     LNR"
     gene            complement(33048..33203)
                     /locus_tag="VQT46_000840"
                     /pseudo
     CDS             complement(33048..33203)
                     /locus_tag="VQT46_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
BASE COUNT         9515 a         6538 c         6861 g        10410 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagaa acccctcgag aagagaaacc gcaaagcgag
       61 aaaccagagt ctccaaaacc aacagaggaa ccagaagaag aatcaccaga ggaatcagaa
      121 gaacctcagg tcgagactga aaaggttgaa gaaaaaatga gagaggctga agatttactt
      181 ggaaaaatcc aggatccaat tatcaagtcc aatgccaaag agactctcac aggattaaaa
      241 aataatttac tatttggcac ccaggacaac aatactatta tggcagaagc tgaaaaacta
      301 ttggctttat taaaggagag taagtaaagg tagcagcatt ttctaactcc taaaaacagg
      361 ataggagaac gggaaaacga aaaatgagag cagaatgtga gttctagttc tcattttttt
      421 catgaaaatg tgcaaaatat agtagattga aactagaata gtatacctct acttctaaaa
      481 cattgttaga aatcgatttg actgtcctgt tcttatttca ttttactata tcttaacaga
      541 tagtgtaaat aaagataaac tatttactgg ctaattaatc agttaaacac tagttaagga
      601 gtaatgatga aaaaaagaac aatactatta ttgatggcca gtctgttagc tcttgtctta
      661 ggagcatgtg gtttcttgga catattgatc ctggatcatt ctcatcagga ttactcttta
      721 ctgctatttt agaaactggg gtggtttgat ggaaagtatt ggtattggtc ttgttatcgt
      781 ttcacattcc aaacacattg cagaaggtgt tgttgaactg attagtaaag tagctaaaga
      841 tgttccgatt acttatgtag gaggaaccga gggcggagga attggaacga gttttgatca
      901 agtagatagg gttgtttccg aaaatccagc agatacttta cttgcctttt ttgacctagg
      961 ttctgctata aaatgttaag taaatgattt caaaatcaga aagggattgc tttgggcagt
     1021 tcctttttaa tgtaaatgta aaaggagtag aatcatagtg tttctaaatt gtgaatcaat
     1081 caaaactgat tgtgatgggg ctattctagc tttagaatcc ttcaaaaatt aaaatttaag
     1141 gcaatcaatt acttggaaga gtatgaaagc atttagttta taggaattct aggcctagaa
     1201 ttacatatgt atttatgaag ataggggtgt tcgatagtta gtattgttct gttctgaaag
     1261 atttgagctg tcagttgtat agaaagtgtt cgaatttttt ttaagtgatt aaattagtta
     1321 attgtatgag gttctttatg atataatgtt cttaatgaat tttcagaaag gaaaacctca
     1381 aattgttcta caaatttcta ctcttcgacc tcgaccacac tcttcttgat tttgatgctg
     1441 ctgaggatgt ggctttgacc caacttctaa aagaagaagg agttgcggat attcaggctt
     1501 ataaagatta ttacgttcct atgaacaagg ctctctggaa agacttggag ctgaagaaaa
     1561 tcagtaaaca agagctggtt aacacgcgct tttctcgttt atttgctcat tttggacagg
     1621 aaaaagacgg tagttttctt gcccagcgtt accaatttta cctcgcccag cagggacaaa
     1681 cactatcggg cgctcatgat ctcttggaca gcctcattga gcgtgattat aacttgtatg
     1741 ctgcgacaaa tggcattact gccattcaga caggacgttt ggctcaatct ggtctagcac
     1801 cttatttcaa tcaagtcttt atctcagaac agttgcaaac tcaaaagccg gatgctctct
     1861 tttatgaaaa gattggccag caaattgctg gatttagtaa agaaaagacg ctgatgattg
     1921 gagattctct aaccgccgac attcaaggtg gcaataatgc ggggattgat actatctggt
     1981 ataatcctca tcacctcgaa aatcacacac aagcccagcc gacttacgaa gtctattctt
     2041 accaagactt gctggattgt ttagataaaa atattcttga aaagatcaca ttttaaagga
     2101 gacgagctaa tgactacaaa aaagctaata ttactattga agagtacatt gaaatgtctg
     2161 aagttgattt taatgaagct gttaattatg aatttacatc tgacacttgt caattagcaa
     2221 atagtattta tcaatctctt tttaagtttt ttgataagaa aaatttctct ggcgatttaa
     2281 tttttacttg gaaatctcca tcattagtca aagaagggga ttatattggg agaagggatt
     2341 cacaagtaga taatcttaga gtaataggaa atatatttcc gaattatctt actaatcgaa
     2401 aatatagcct caatatgaat cgtaatggct gtatgggaga ttttcctcat gacttttttg
     2461 atatatacct agatcatgta gcaaaatatg cctacgaaca aaaagttaat aatattaaag
     2521 agtattatcc tttaaaaaga gcgattttac accaagagaa tgcattgtat tttcgatttt
     2581 tttctaattt tgacgacttt ttagaaaaaa attatttaaa gactatatgg caagtttcta
     2641 aagaaactcc tttttctgaa atggatttta atatgtttaa aaatatttca gaaaagataa
     2701 tcttcgaaag aggtagtaaa atgcttaatg atttaaaaag taattataaa aaatagccag
     2761 tctttataaa ctgtattcac gtattcaaat cgtatatagt cgatttatta aatctttaga
     2821 taaactgtaa aaagtggttt ccatagccac tttttgctat aatagaggca gtaaaaatga
     2881 aggagtcggc tatggaacac tcgtcttggc atgctttgat taaggcgcaa ttacctgagg
     2941 gttatttcgg gaaaatcaat cagtttatgg agcaggtcta ttctcagggg attatttatc
     3001 cacccaagga aaaggttttt caggctctct tgacaacact gcttgaagaa gttaaggtgg
     3061 taattctagg gcaagacccc tatcacggac caggtcaagc gcagggcttg agtttttctg
     3121 tacctgactc tatcccagct ccaccatcct tgcaaaatat cttgaaagaa ttgtcagatg
     3181 atatcggagt taagaaatct catgatttga cagcttgggc tgagcaagga gtcttgcttc
     3241 ttaatgcttg tttgactgtt cctgctggac aggccaatgg tcatgctggt caaatctggg
     3301 agccttttac tgatgctgtg attcaggtgg tcaatcatct agatagacca gtcgtttttg
     3361 tactctgggg agcttatgca cgtaagaaga aggccttagt taccaatcct catcacttga
     3421 ttatcgaatc agcccatcca agtcctttgt cggtttatag aggattttgg ggttccaagc
     3481 ccttttccaa ggccaatgca ttcttaaaag agacaggaca agagccaatc gattggctta
     3541 gataaggaga aaatatgcct cagttagcga cgatttgcta cattgataat gggaaagaac
     3601 tgctcatgct ccatcgtaat aagaaaccca atgatgtcca tgaagggaaa tggattggtg
     3661 tgggtggtaa gctagagaga ggagagacgc cccaggaatg cgcggcgcgt gaaatccttg
     3721 aagaaacagg gctcaaagcc aagccagttc taaaaggtgt catcactttt cctgaattta
     3781 caccagattt agactggtac acctatgttt ttaaggtgac ggagtttgag ggcgacttga
     3841 ttgactgcaa tgaggggacg ctagaatggg ttccctatga cgaggttttg agcaagccga
     3901 cttgggaagg tgaccacacc tttgttgagt ggcttttaga ggataaaccc ttcttttcag
     3961 ccaagtttgt ttatgatggg gataaattgt tggataccca agttgatttc tatgaataaa
     4021 ggagaaagca gatgctacta atcaaaaatg gtcgtgtaat ggatcctaag tctggtttgg
     4081 atcaagtttg tgatgtctta gttcaagatg ggaaaattat caaaattgcg cctgagatca
     4141 cggaagaagg agcagaaacg attgatgcta ctggtcttgt ggttgctcct ggtttggtcg
     4201 atattcatgt gcatttccgt gaacctggtc aaacacataa agaagacatt catactggtg
     4261 ccctggcagc cgctgcaggt ggttttacta ctgtcgtcat gatggctaat accagtccaa
     4321 ccatttcaga cgtggagact ttgcaagcag ttctccagtc agctgccaaa gagaagatta
     4381 atgtcaagac agttgcgacc attactaaaa actttaatgg taaaaacttg actgacttta
     4441 aggcgctctt agaagctggt gcggttggtt tctctgatga cggtattccg cttgagagca
     4501 gtaagattgt caaggaagcc atggaggaag ccaaaaaact caataccttt atcagccttc
     4561 atgaggaaga tccaggtttg aacggtgttc ttggctttaa tgaaaatatt gctagagaac
     4621 atttccatat ctgcggtgct actggggtgg ctgagtacgc tatgatggcg cgtgatgtca
     4681 tgattgccta tgcaactaaa gcccatgttc acatccagca tttgtctaag gaagaaagtg
     4741 ttaaagtagt ggagtttgct caggggttag gtgcagaagt cacagcagaa gtagcgccac
     4801 agcatttctc taagacagaa gcacttcttt taacacaagg tagcaatgct aagatgaatc
     4861 caccgcttcg tttggaatca gaccgtcgtg ccgttatcga aggtctcaaa tcaggtgtca
     4921 tcacagttat tgcgactgac cacgcgcctc atcatgtaga tgaaaaaaat gttgaggata
     4981 ttaccaaagc gccatctggt atgactggct tagaaacatc cctgtctctc ggcttgacct
     5041 atttagtaga agctggtgag ttgagcttga tggaattact tgaaaaaatg acatacaacc
     5101 cagccaagct ttacaacttt gaagcaggtt acttggctga gaatggtcca gcagatatca
     5161 ctatttttga tgccaaggct gaccgccttg tggactccca ttttgcttcc aaagcagcta
     5221 attcaccatt catcggtgaa accttaaaag ggcaggttaa atataccatc tgtaagggac
     5281 aaatcgtcta tcaagcttga taggagttag aatatgaatt attttcgaaa acgtagggag
     5341 agacaagcga aatctaatag tggaatttac tgtcccgcag ctaatcgttc caaaattcaa
     5401 tatgaaacta aagaaaaagc tgaccatgcg gttcaatatg ataacggagg tttagttaga
     5461 agctattatt gtcgtacatg tgcgtgttgg catactactt caaaatctaa taaacctccg
     5521 ctaagtttga aaaactatgg tctgaaactc tttggtttag ataaatcaga atagaaagag
     5581 aagtatgtat aagacaaagt gtttacgaga gaagttagta ttatttttaa aaattttctt
     5641 cccaatcctg atctaccaat ttgccaatta ttctgcctct tttgttgata ctgcaatgac
     5701 aggtcaatac aacactatgg acttggctgg tgtatctatg gcaaccagta tctggaatcc
     5761 tttctttaca tttctaacag ggattgtgtc agccttggtg cctatcattg gtcaccatct
     5821 tggtcgaggc aaaaaggaag aagttgcgtc tgatttttac caatttattt atttggcctt
     5881 gggcctatct gtggtcttgc tggggatggt acttttcttg gcaccaacaa tcttgaatca
     5941 tattgggtta gaagcagcag tagcggcagt agcggttcgc tatctttggt ttttatctat
     6001 cgggattatc cccttgttgc tctttagcgt cattcgttcc ttgctggatt cgctgggctt
     6061 gaccaaactg tccatgtacc tcatgctttt gttactccct ctcaatagcg gatttaacta
     6121 tctcttgatt tacggtgcct ttggtgttcc agaactggga ggggctggtg ctggtttagg
     6181 aacatccttg gcctactggg tcttgcttgg gatttctgtt ctggttttat ttaaacagga
     6241 gaagctcaaa gccttacacc ttgagaaacg aattccactt aatatggata aaattaagga
     6301 aggagttcgt ttaggtctgc ctattggggg aactgtcttc gcggaagtgg ctatcttttc
     6361 agtggttggc ttgattatgg ctaagttttc gtccttgatt atagctagtc accagtcagc
     6421 tatgaacttt tcaagtctta tgtacgcctt tcctatgagt atctcatcgg ctatggctat
     6481 tgtcgtttcc tatgaagtgg gagccaagcg atttgatgat gcgaaaacct atattggtct
     6541 aggaagatgg actgccctca tttttgcggc cttcacctta accttccttt acatttttag
     6601 gggaaatgtg gccagtcttt atggtaacga cccaaaattt atcgatttga cagcgcgttt
     6661 tttaacttat agtcttttct tccagttagc agataccttt gcggcgccgc ttcagggaat
     6721 tttgcggggg tataaggata cagttattcc tttttacctt ggtttgcttg gttattgggg
     6781 cgtagcaatc cctgtggcta cgctatttga ttccctaaca gattttggag cttattctta
     6841 ctggatcggc ttgattatta gtttgattgt gagtggggcg ctctaccgtt ggcgtttaac
     6901 tgtgattatg aagagatttg aatctttagc aaaatccaaa cgctaaaaag tttgtgaaaa
     6961 aatattcttg ataagaaaat cccttgtttt cacggggttt tcttttttat tttgtgaaat
     7021 ttcttttaga aaaactttga cagtatttgc caaaaacggt aaaatagtaa ggtaagaaga
     7081 aagttagaaa ggcaagaaga tgtcaacttt agataaaaat cttttgctag aaatgttccg
     7141 taagatggaa gaaatccgtc gcatggactt aaaaattgca caattagtaa agaaagggaa
     7201 agtgccagga atgacgcact tttctgttgg tgaagaggca gctaacgtgg gggctatgtt
     7261 agctctcaat ccagatgatc tgattacctc aaaccaccgt ggacacgggc aagctattgc
     7321 taaagggatc gacctcaacg gaatgatggc tgaaatcctt ggtaaataca ctggaacctg
     7381 taaagggaaa ggtggatcta tgcatatcgc tgaccttgat gctgggaacc ttggtgccaa
     7441 tggtatcgta ggtggtggta tggggatcgc tgtcggtgca gccctcagtc agcaaatgca
     7501 aaataccggt aaaatcgttg tctgcttctt tggagatggt gcgaccaatg aaggtgtttt
     7561 ccacgaagca gtgaacatgg cttctatctg gaacctgcca gtcattttct attgcattaa
     7621 caacggttac ggtatctctg cggatatcaa gaaaatgacc aatatagaac atatccatca
     7681 acgtagcgcc gcttatggaa ttcctggaat gttcatcgaa gacggtaaca atgtcatcga
     7741 tgtctatgaa ggatttcaga aagctgtaga ccatgttcgc agtggcaatg gtccagtctt
     7801 gattgaaagt gtaacttatc gctggctcgg tcactcatca tctgaccctg gtaaatatcg
     7861 tacgcgtgaa gaagtggaat tgtggaaaca aaaagatcca atcgaaaacc tccgcaatta
     7921 ccttattgaa aataacattg caagtgccga agaattggaa gaaatccaag cgcaagtaaa
     7981 ggaagcagta gaagcttctg ttaaatttgc agaggaaagc ccattcccac cgcttgaatc
     8041 agcctttgaa gatatttacg cagactaagg agaaagagat aaaatggaaa caaaaacaat
     8101 gtccttccgt gacaccatta tccttgctat gtctgaggaa atgcgtcgcg atgaaaatgt
     8161 gttcttgatg ggagaagacg tcggtgtctt cggaggagac ttcggtactt ctgttggaat
     8221 gcttgaagaa tttggtccag aacgcgtccg tgactgtccg atttctgaag ctgccatctc
     8281 tggagcagca gcaggagcag ccatgacagg acttcgtcca atcgtcgata tgaccttcat
     8341 ggacttctct gttattgcca tggacaatat cgtcaaccaa gctgctaaaa cacgttacat
     8401 gtttggtggt aaaggtcagg ttccaatgac tgttcgttgt gcagctggta acggagttgg
     8461 ctctgccgcc cagcactcac aatctctaga gtcttggttt actcacattc caggacttaa
     8521 ggttgtggca cctggaacac ctgcggacat gaaaggcctg cttaagtctt ctatccgtga
     8581 taaaaaccca gttattatac ttgagtacaa gtcagaattt aaccaaaaag gggaagtgcc
     8641 agttgatcca gactacacaa ttccacttgg ggttggtgaa atcaaacgcc aaggaacgga
     8701 tgtaacagtt gttacttatg gaaaaatgct tcgccgtgtg gttcaagctg ctgaagaatt
     8761 agcagaagaa ggaatttcag ttgaaattgt tgacccacgt acccttgttc cgcttgataa
     8821 ggatatcatc ataaactcag tgaagaagac tggtaaggtt gttctggtca acgatgccca
     8881 caaaacaagt ggctatatca gtgaaatttc agctattatt tcagaatcag aagcatttga
     8941 ctatctagat gcaccaatcc gccgttgtgc aggagaagat gtgccgatgc cttatgcaca
     9001 aaacctagaa aatgcaatga ttccaacagt tgaaagtatc aaagatgcaa tccgaaaaac
     9061 ttataacaaa gaatagagtt acataagata agttatgtaa ataaaataaa gctgacgaga
     9121 aactttgtat cttttaggtg cagagctctt cgtcattaat atcttatatt cgagcacggg
     9181 ctaaaagctc ggaaaaaaga taaatctcct tggcttcatc gaagccatcg tcgatttcct
     9241 atttttcagt cgcttttgac gccctttgta tcataaatag aattggagag gtcatggctg
     9301 atgacaagct aagagcgact cctgcagcta gaaagttagc ggatgattta gggataaacc
     9361 tctacgacgt ttctggctca ggtgcaaacg gtcgtgtcca caaagaagac gtggaaactt
     9421 ataaagacac aaacgtggtt cgcatttcgc cacttgcaaa acgaattgcc ctcgaacata
     9481 acattgcttg gcaggaaatc caaggaaccg gtcatcgtgg taaaatcatg aagaaggatg
     9541 ttttggccct gcttcctgaa aatatcgaaa acgatagcat caaatctcct gctcagattg
     9601 aaaaagtgga agaagtccct gataacgtaa caccatatgg tgaaatcgag cgtattccaa
     9661 tgacaccaat gcgtaaggtt attgcccaac gcatggttga atcttacttg actgcgccaa
     9721 ccttcaccct caactatgaa gttgatatga ctgaaatgtt ggctcttcgt aagaaggttc
     9781 ttgagccaat catggaagca actgggaaga agactactgt aacagacctt ctttcgcttg
     9841 cagttgttaa gactcttatg aaacacccat acatcaacgc ttcattgaca gaagatggca
     9901 agactattat cactcacaac tatgtcaatc ttgccatggc agttgggatg gataatggat
     9961 tgatgacacc tgttgtttac aatgctgaga agatgagtct ttcagaacta gttgtagcct
    10021 ttaaggatgt tattggccgt accttggatg gtaaattggc tccaagtgag ttacaaaatt
    10081 caacattcac aatcagtaat ttgggaatgt ttggtgttca gtcctttggc ccgattatta
    10141 accaacccaa ctcagctatc cttggtgtca gttcgacaat cgagaagcca gttgtcgtca
    10201 atggtgaaat tgtgattcgc ccaatcatga gtttaggatt aaccattgac caccgtgtcg
    10261 tagatggtat ggctggtgct aagtttatga aggacttgaa agagttgatt gaaaccccaa
    10321 tctcaatgtt gatttaagag caagagtatt catttttaag atatagataa aggaaggaag
    10381 acatggcctt agaaataatt atgccaaaag ccggcgtgga tatgacagaa ggacaaatcg
    10441 tccaatggaa taaaaaagtc ggagaatttg taaaagaagg agaaatcctt ttggaaatca
    10501 tgactgataa agtcagcatg gaattggaag ccgaagaaga tgggtacttg attgccattc
    10561 tcaaaggaga tggtgaaact gtccctgtaa cggaaattat cggttacctt ggtgaagaaa
    10621 gggaaaacat cccaacagct ggagcagcat cgccagaagc tagccctgta cctgtagcaa
    10681 gtacctcaaa cgatgatggt aagagcgatg atgcttttga tatcgttgtg attggtggag
    10741 gtcctgctgg ttatgttgca gccattaaag ctgcccaact cggcggtaag gttgcccttg
    10801 ttgagaaatc tgaacttggt ggaacctgct taaaccgtgg atgtattcca accaagacct
    10861 accttcataa cgctgaaatt attgaaaata tcggtcatgc tgcaaatcgt ggtatcgtga
    10921 ttgaaaatcc taacttcact gttgatatgg aaaaactttt agaaactaaa tctaaagttg
    10981 ttaatactct tgttggtggt gttgcaggac ttcttcgtag ctacggagtt actgttcata
    11041 aaggaattgg tacaatcact aaagacaaga acgtcttggt aaatggttct gaattgcttg
    11101 aaaccaagaa aatcattctt gctggtggtt caaaagtcag caagatcaac gtccctggta
    11161 tgcaatctcc acttgtcatg actagtgatg acattcttga aatgaacgaa gtgccagaaa
    11221 gccttgttat catcggtggt ggagttgtcg gtatcgaact cggtcaggcc ttcatgacat
    11281 ttggttcaaa agtgactgtt atcgaaatga tggaccgtat agttccagct atggatgcgg
    11341 aagtttctaa gaaccttcgc ttgatccttg agcgtaaagg aatgaccatc ttgactggta
    11401 ctaaactgca agaaatcatt gaggaaaatg gtcaacttcg tatcaaggtt gaaggaaaag
    11461 acgatatcat cgcaagcaaa gctcttcttt caattggtcg tatgccagac cttgaaggta
    11521 ttggagaggt tgagtttgaa ttggatcgtg gttgtatcaa ggtcaacgaa tacatggaaa
    11581 cttcagttcc aggcatttat gcaccaggtg acatcaacgg tactaagatg ttggctcacg
    11641 cagctttccg catgggtgaa gtttccgctg aaaatgccct taaaggaaat catgcagttg
    11701 ccaaattgaa tttgactcct gcagccatct acactctccc tgaagtagca gcagtaggtt
    11761 tgacagaaga acaagcccgt gagaaatacg atgttgccat cggtaagttt aactttgctg
    11821 ctaacggtcg tgctattgca tctgacgcag ctcaaggttt cgtaaaagtt atcgctgata
    11881 agaaatacgg agaaatcatt ggtgtacaca ttattggtcc tgcagccgca gaattaataa
    11941 acgaagcatc aagcatcatc gaaatggaaa tcactgttga ggaaatgctg aagaccatcc
    12001 acggacaccc aacttactct gaagtgatgt atgaagcgtt tgcagatgtt ctaggaatgg
    12061 ccatccattc acctaagaaa aaataaaacg aagatagatt agactggaag gttatttcca
    12121 gtctctatca tataaagtaa agggatatca tgaaatacat tatcaatcat tcaaatgaca
    12181 ctgcttttaa tattgccttg gaagaatacg cctttaaaca ccttttggat gaggatcaaa
    12241 tcttcctact ttggattaac aagccatcta tcattgttgg tcgtcaccag aacactatcg
    12301 aagaaatcaa ccgtgattat gttcgcgaaa atggtattga ggtagttcgc cgtattagtg
    12361 gtggtggagc tgtttaccac gatttaaata acctcaacta cacgatcatc tccaaagaag
    12421 atgaaaataa ggcatttgac ttcaagagct tctcaactcc ggttatcaat accctggctc
    12481 aactcggggt taaagctgag ttcacaggtc gtaatgacct tgagattgat ggtaagaagt
    12541 tctgtggcaa tgcccaagcc tatatcaacg gccgtatcat gcaccacggt tgcttgctct
    12601 ttgacgttga tttgtcagtc ctcgcaaatg cccttaaggt ttcaaaagat aaatttgaat
    12661 caaaaggtgt gaaatccgtc cgtgcccgtg taaccaatat tatcaatgaa ttaccaaaaa
    12721 aaatcacagt cgaaaaattc cgtgatttac tcttggaata catgaaaaaa gagtacccag
    12781 agatgactga atacgtcttt tcagaagaag aattggccga aatcaatcac atcaaggata
    12841 ctaagtttgg aacttgggac tggaactatg gtaaatcacc tgaatttaac gtccgtcgtg
    12901 gaaccaaatt cactagtggt aaggttgaag tctttgctaa cgttactgaa tcaaaaatcc
    12961 aagacatcaa gatttatggt gacttctttg gtattgaaga cgttgctgca gtagaagatg
    13021 tccttcgtgg ggtgaaatac gaacgcgaag atgttcttaa ggcgctaaaa accattgata
    13081 tcacacgcta cttcgctggt attagccgtg aagaaatcgc tgaagcggta gttggataaa
    13141 tcaaaaaaag aagttggcca acttcttttt ttgatattta tttacataat ttaaaatacg
    13201 tgaaatcata aactatctag agcattcttt tgttcatcat taacaatatg ggtatagagg
    13261 tcagtgactt gtgtgctggc atgtcctagt tggtgactga ctaaaacttg tgatttagtc
    13321 gcatcataga gcctagttgc tagcgtatgg cgcagtttat ggggtgttac acgtacttta
    13381 aaatcctctg agtatttagc aaccattttc tcaacgctag aagcatcgat acgattagga
    13441 acacctctgt agagagttaa aaaaagggct gtatctgttt tttccgtttt atagcgttga
    13501 ttccgaatgg ccagataatt ctctaaataa ggtttagcaa aagcagcgac attgactgag
    13561 tcacgtttgc caccttttcg agtaacatca ataaccatca tttttagatt gagatctctt
    13621 agatctagat taacagcttc agataagcga acaccagatg ccaagagaag ggcaataatg
    13681 gctaaatctc gttctttatt tttgttgaat gatgagagag ctcgatttga aagctgttgt
    13741 gggtgctctt gatcgatata agttagaaaa ccttctgttt catcacctag aaagagtttt
    13801 tgcttgatat tttcagctct ggcagcaagg gtttctttct ttttcttggt tgaaactttt
    13861 ttcattacat tacgatagaa ataaggttcc ccctgatcgt tttcaacctc ctcggttaga
    13921 tacttgtaaa gactagaaag tgctgataag gttcgattga tagttgtctg tgaaacacct
    13981 tgttttgttg tattagcatt cagcaaggga cgttcacgta gataaaggat aaaggattcc
    14041 atgtctttct tagacatatt ttccaaaact gataaaggaa tatcggatat tttatcagcg
    14101 tttgaaatac cagactccaa aacccagctg aaaaatcggt catattcctt aaggtattcg
    14161 tacagggttg taaaactgta gggcacagcc agcttagatt ggtagtattc cagaacatac
    14221 cagggcatga gttgttttag tttgtcgatt cgttccagta aaatctcacg tttcatgtat
    14281 tttctccata agtaagtata ctagtagtat agcatagact tgtatatttt tcaagaaaat
    14341 tatagttttt cagaaagatg ttataggagt ttttcaaagt gataaaaaga cttagaccta
    14401 caaacaaaac agaataagga aaataataaa aatctcaccc actaaacttc tgttaatact
    14461 acataactga agagctatat aaggagctat gagatacaaa acacattgta taatagattg
    14521 aaactagaat agtacatctg gacttctaaa acattgctag aaattgattt gattgttctg
    14581 attgttttat cctatttcta tttcatttca ctatataatt gctattgttt tctttttcat
    14641 gattttaatc ttactgtaca gatttgatac agtaaactcc tttctagctt tatactttat
    14701 catttctaac ttaattatag tcttattttt aataaagttc aattatttat atgtaaaatt
    14761 cctcatcagt aaaaaataac cgatctcatt tctgagaatc ggttttctaa ataaatcaag
    14821 ctgagtattt acataacata aattatgtaa atactcatac tacaacaaca aatctttgac
    14881 ttttccaatt tcactttttg gaataaccag gtgaatcata tcacccagat acattctggt
    14941 tgagccgtta actgtttggc tcttgccatt atggacttga gttgtgatga ggacgttgtg
    15001 tggtaagttg agttcatgaa cttgtttccc agcaatttta tcagaaactg gtatttcgat
    15061 aagtgtaact tctccttcgc tagatacttc ttctggaagc attttttcca gcatggcttc
    15121 atagactggc gtacctttga gcaaatccat gataatataa gaaacaagag tgacaagacc
    15181 aagtggcatg aggttgcgaa tatctcctac catctcagtt acgaggatca tagcggttaa
    15241 gggagctttt gatatggctc caaaatagcc actcattcct agaatgacaa atatagggaa
    15301 ttgctcttga ctgacaagtc caagattgac acagataaca ccaactaagg aaccaagcaa
    15361 agaaccaaga gctaaaatgg ggaggaaaat tcctcctggc agtccacttc catagctaat
    15421 catactccaa ataaagcgga tcaaaaagta agctaataaa acttggaaac taaaattttg
    15481 ttcagttaaa gaaaggacaa gctgatttcc gccaccaatg atttgaggta agaagattcc
    15541 gactggtatg ataatgataa aagccaagat gggataataa gccctatcca aatggatttt
    15601 ttgaccaatc aagtcataaa ctcttccaac gtttaataca gctttctcat agagaaaacc
    15661 tgaaaatcca aggaaaattc ccatgacgag atatatccaa tactggtcta gggtcatggg
    15721 aggaatgtta tctggcatat ccaatactgg tgtcaaaccg aacatgagta gagacacaaa
    15781 gtttgctacg atgctggctg ctagagttga gacccagaaa aagcgcgaaa aatggtgata
    15841 gacttcttct acaacaaaga gaagtgctgc aataggagca ttaaaggctg cggctaaacc
    15901 tgctgcagct ccactggcaa tcaaggaacg ttcctctact ggactggatt tgagccactt
    15961 ggcaattcct ttaccaccaa ctgctccaag ttgaatgctg ggtccctctc gacccagcat
    16021 gagtccactg gcaatagcaa gaatacctag cacatatttt ttccaaagaa tgccccacca
    16081 gttgagggac atgaggcctt tcagttcggc ttcgacttga ggaattcctg agcctttaat
    16141 atctttttct gaccgtgtta gtttggcact gagccaacag atgagtatat aaaacaaaac
    16201 cagtacaaaa agattgcgca ctaagtaccc ttgatcttga taaactcctt gtatcaggtg
    16261 gaagcccttt tcaattaaga aacgaaagga tccgacgata attccaacga tgaggccgac
    16321 aatgattcct cgaccaactt gggatagtat agtgctggat gcaaaggcga attctttctt
    16381 agaacggact atttccgact gttcctccat ggtatttcct ttcaattaac tttctttttt
    16441 acctaaaacc agtgatttaa cgggttcaaa gctggttcgg tgaattgggg taactcctag
    16501 ttttgtgagg ccttccagat gtttagctgt gccatatcct gcattagtag cgaaatcata
    16561 gccagggaac tgctgatcgt attccttcat caattcatca cgtgttacct tggctactat
    16621 agatgctgct gcgatagaga gggagttggc atctcctttg ataatggagg tttgtgaaat
    16681 gggcaagtcc agtttcatgg catcaatcaa aaggtgctct ggttgagggc tgagctggga
    16741 gattgcttct tgcatggcta gtttggttgc ttcatagata ttgacttggt cgatgacctg
    16801 attatctatg ataccaattc caatcgacaa ggcttggtct tgaacgactt ggaaaatctc
    16861 cagatgtttc tttttaggaa ttttcttgct gtcgttgaga cctttaatct tacaattttt
    16921 aggtaaaata acggccgcag cgactacagg accagcaaga ggaccacgac caacctcatc
    16981 aatacctgca attaaggtca atccttgctt ataaagttct ttttcataag aaagcatgga
    17041 ttccaagcgc aaattttcat ctaattcagc ttgaatggct cttttatgct tgctgatttc
    17101 cttttgaact cctgagcgat tatccttttc aagatctaaa aaaatagggc tttctaactc
    17161 cttgactgtc acaaggagtt ctttgatttc tttaatcgtt gccatcgagg ccttccaatg
    17221 tatctaaggt atagttaccg agtttgccat cacggacttc cttcacgaag agactgtaaa
    17281 aacggtcata gtcatcacgg aaaccgaggg cgcgggtcat atccataata atcacaggcg
    17341 cttcttcttc aattttcatt tgtttgaagc gttcagccag cttttctgga taatgttctt
    17401 tgaaataatt gataccaaaa atggtaacct catccatagg aagcaactga tccttgatag
    17461 ctccagtcaa tgccaactta agtgcaacag tttcatcctc aaacttaggc cagagaatcc
    17521 ccggtgtatc caagatttcc agatctttat tggttttaag ccattgttga ccttttgtga
    17581 cccctggctt gtttccaaca acagcaatct ttttaccagc caaacggttc atcagagttg
    17641 atttaccagc gtttggaatc ccaataatca tggtacgcaa ggtttcaatc tgaatcccac
    17701 gttctttctg gcgagcaatc ttatcagcca tgagcttctt ggccgcatct gttacaactt
    17761 ttacagtcac ttgctctttg gagttgatag ctagcgtctg gattccttgt gattcaaaat
    17821 actgacgcca ttccttggtc attgctggat cagccaagtc ggccttgttt aaaatcaaga
    17881 gttttggttt atcaccaaca atcttggtta acataggatt ttgactagat agaggtaagc
    17941 gtgcatcaac taaaatcgtc acaaaatcaa caaattttaa attctcctgc acctgtcgac
    18001 gagctttaga catgtgacca ggaaaccatt gaatagtagc cattgagttt tttcctttca
    18061 tagcaaggat ttagatcccc tattttattt tactattgtt tgaacataga gagttttcaa
    18121 atgaatgatg tccaaacagt tcttgtttta tgacatagaa atctacttta tattatatca
    18181 tgccttcttt attttgtccg atgatagcct tttaccctat atagaaaaaa gccatcaaat
    18241 gatgactttt cagagggagc aaaaaactgt tcccgtcata ttatgaacca aaagaactaa
    18301 actaccaaca gctaataggc ctaaagctgt aagtgcagaa gttgatgaac ctgttgcagg
    18361 aagagtttcc tgctgataaa taagagcata acttacttca ttatcagtag gaattcctgc
    18421 ttgaatcttg gtttgttctt catcaccttt ttaaacttta tttcctaata gtaaacacta
    18481 ttttttattc tcaaaaattg aacttctaaa atcatttgtt tggtcaagat aggctttaaa
    18541 gattgctctc ttcaacttat gaacggcact gtcgatttct ggatcataat tactccaacg
    18601 tggaccttca gcatccttga gaacagcttg gtccatgagg gcttgcaatt catccacatt
    18661 attgatagtc tttgtgccat agcttggcca tggttttgtc ggatctttaa aggtcacctg
    18721 cttcaagttt ccaaactgat ccactcgttc ttggtacata gctgtcttaa attctgccca
    18781 agttttatac ttaccgtcaa ataccttttt caaaacaagc tcatcggtca ccaagccccg
    18841 ttctttacca taaagattga tagtttgccc ttgttgttta gcatcttctt cgtattggtt
    18901 tgagatataa ggtaccattc catccttaaa gcctttggca gccaaaagtt cgtacgcaat
    18961 cctacgtccc ataaggtccc ctggtgtgcc tttctcactg ctgagagctg aatagattgg
    19021 ggcaaagagt ttgatggtat agtagccatt tcgttcatag tcgccagact ggtactcacg
    19081 agctgataag atgttgtggt caatcaaact ttcaaaacta ttcaggtttc gggcctctgc
    19141 ttctgtcaat tctttgacta cgttagtggc ataaacctca tttccatctg ctggatcttt
    19201 cacatacttg ttctcaattt ttctgagagc cgccattttc tggtaaacac ttagtttatt
    19261 aacgattgac tgcccttcga gatattccat catgtagata aggtcaaaca tgttatggac
    19321 atagttctga agatctgctg cgttttggaa tctctctgtc ggatccaaga cttgaagacg
    19381 ggatccctct gtactatctg attttgagtg tttcaagata gaattaatgg taatggttgc
    19441 gtcacttggt tggtcagggg cttgcaataa gccttttgcg aagaactctg gtcccaagcc
    19501 atttcttcga ccatagccac caaggtaaat atcctgatcc gaatcatggg tcatttcatg
    19561 ggtataagta atggctccat ccttgtccag catgcggtaa gacatatagt agacgccgtc
    19621 ccctgtagcg taggctccat gctggttgtg tactacctta ttgccaactg gtccaaagaa
    19681 gttcttcata gctggattgg agctatcaaa cttagcctcc gctgtagctt ttcctgatgt
    19741 tgtgtcatcc ccaaacttat aggcatcata aaggagaatc gtacgataga gtttttcgcg
    19801 tgactgttca tctaaaatac gataccaata atcgtagtga tctcgctgac gtttggctgt
    19861 ttcacgcgca ttttcttcaa caaaatcatt gagagccttg cccgctttat ggtcactact
    19921 gcggtagcga tcataagctc caaatcctag actagacatg gtcgagatga caaatacgga
    19981 tctctctggc aaggtcagga gaggcaagac catattgcgg tatttccatg tggcactcgt
    20041 gatacgatca taaacaccga tagaatactt ggtgccagct aacccttgct tcgttttcac
    20101 ctcttcgata gtggattttt cttcgacaat gtaagcctta gtctctgatt taaaccagtc
    20161 attattgctt gtatttggta aaaagacttt tcggtaatgt tccagcgtgc taaacaaatc
    20221 tgtcgttcca tgttgactgg caagactgat accataagta tcgacattat tcttagctag
    20281 aagattgtta aagccagatt tacctaactc aatcagagta tctagtgggg aagtatttcc
    20341 tttaccaaag aagtctggat gatacataac taggtctttg acattcactt gaccatagtt
    20401 aaagttatac caacgttcta aataagttaa accgagtagc aaggcttcct tattattctt
    20461 gattttatct acaagatagc ctctggtgac tgagttatcg ctagctagac cggcatctgc
    20521 tgacaaaagt tttttcaagc tgtctcccag attttgtttt gttttggaga actggtcttc
    20581 taaatagagc tcggttaact taacttctgg agaaatacca agtgtctttc tgatagcatc
    20641 tgactggtaa tcaagcttct gcaactcagg caagacttcc ttaacaatag agtctcgatc
    20701 atataagaat tggttaggag tgtagagaag tcccgtatta cctagattat attctgctag
    20761 attggcaaaa tcagtctggt acttgagatc aaatttctca gatgaatggt cattatagtg
    20821 aagtaagagt ttgtttgcag tctgtttgtt ggaaacaata tctgtgatta cttggtcatc
    20881 cttcatcata actgcagata agagttcttt ttggtataag agactgttct ccttaaccag
    20941 gtttccgtat ttgacgatgg ttgacttatt ataaaaaggt aacaattttt caatgttctt
    21001 ataaaccaaa gcacggttag cttgataatg ggctatctta gaaaaatcac tgtctttctt
    21061 gccacttgtt gagaggggtt ccaccgttgg tagagtgaga ggatttattt ctgctttttt
    21121 gcttacaatt tgagaagcat ctagcattgt tcctctttct tcaaaggatt ccttgctgac
    21181 gacctcatcc ttctctaaag tgacattgaa aactctatta gccttactac taaatgtatt
    21241 agctaccttc attcctgtat agtggtatcc agtgatggca tttccgtttg ttacattgac
    21301 atcgctaaga acattggtca attcaccagc gtgtttttcc tcaccagaag ttcgatccca
    21361 caaatatcct gccacaccag cgactttacc aaagtgcttg acattattaa tatcaccttc
    21421 cgcataactg ttctgtatat gcgcatcttg gtctactaga cctgcaagac caccgacagt
    21481 ctgatctgac ctattggtgt ttgacgaaat ggttactgtc gctttggatt tagcaataga
    21541 cgcatttttt cctgttaaat gaccgaccag accgccaata ttgtaggcat cagtcgtttc
    21601 ataggtattg acaattcttc ccttgaaact gctctctgcg atgcttgatt ggtctgcctt
    21661 agccaacaaa ccaccgacac cacgttctcc agccagaaca ccatcaacat gaacttgttt
    21721 aatctttgtg ccattcgtag cttcatttgc tagtgaacca atatcatttt tccctgaaat
    21781 agcaacattt tttagactca gtttttctac tgtagcacca ctcaagtttt caaacagagg
    21841 ttttttcaaa ttatagatag cataattctt gccatctttt tcaccgatta aacgaccagt
    21901 aaaggtgtcc ttgatatagg atctttcatc aggaccaagc tccacttcgt tagcattcag
    21961 gctggccgct aaatgatagg ttccagaggg attttggttt atagctttga ccaggttgct
    22021 aaaggaagta aagtttgtat tttcctcttt agccttctta tcgaggtaga aggtgaaatt
    22081 gtcgacatat ttattttcta gttcttgctg gagtttctca gctttggctg tgattttata
    22141 aactgactgc ccatttcttt tctcttcagt tattgaagct actggtatat agacatcttt
    22201 aaatgctgaa gattttacct tgacaaagta agtatccgta ttctctggaa ttccatccaa
    22261 tgaaacatgt tgtctgtagg ttccattcgt ctgactatac aactcaatat cagaaacatt
    22321 tcttaattcg agttttttct ctggttctgt ttgtccattc tctgatgttg tattacctga
    22381 attttctggt tttgttgcag ttccgttttt ttctggttga tttgattctt caactggtgg
    22441 ttttgaatca ctaggtttat tggatacttc tccagtattt tcgttagcta ttttcccaga
    22501 gtttgtttgt gtttcttctg caggttgaac tggtttttct gtttcttgat ttgaggtacc
    22561 ttctactgtg ccttcatttg gatttactgg aacttcttct acagtttttt ctgaattttc
    22621 atttttagag tcattatgtt ctggtttatt tgattctcca actgaggttg tcgaatcact
    22681 aggattactg gacacttccc cagtattttc gctagatgta tctggtgata ctttctctga
    22741 attcgttgtt gattcttctg caggttgaac tggattttct gcttcttgaa ttgaggttcc
    22801 ttctgtagta ccttcatttg gatttactgg tgtttcttct gttggtttta ctggaacttc
    22861 ttcagttttt tctggacctt gttctttggt cttctcaacc ggagtttcag gttttacttg
    22921 ctcaatatta cccttatatt ctggcaatgg ggctacctgc tctggttcac ctttatcact
    22981 taccacagta tctggcgact ctggttgaac ctcagtctca cctttgtcgg tcacaactgc
    23041 ttcgggtaat gtcggttgaa cttctggttc gcctttatca cttactacag cttcgggcaa
    23101 ctcaggctga attgcgggtt caacaataga tccagactgt acgtccttat gttctacacc
    23161 agtctcaggt tgttccttta taacttgagt ttttttagta cctttttcga ctattcttgg
    23221 actaggcgca gtcgttgaag ttgaaacaat ttctcgcgaa acttcttcct tgtttacaga
    23281 gaatattctg acgatttcaa ctttcttacc taatttacct tcttgtttta ctcttacagt
    23341 tccttcagct aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtctctat
    23401 agtttcctca cgatataaga gttcaggttt gttcaattga cctgataaaa cttcatcctg
    23461 tggatttaat gtatttaccc cagtcttttc ttttggagaa atcttctcct ctttcttcgt
    23521 ttctagattc ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt
    23581 tcttggattg attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt
    23641 agttgaagaa acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa
    23701 atttggtgta acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc
    23761 ttgattactt acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt
    23821 gtaacctgaa atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt
    23881 attgtaattt agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc
    23941 cattcccgca accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac
    24001 agcaaaaatt aaaattccca gagcagctaa gctagcacca gcaactaggg cttgcctctc
    24061 attcttgctt ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac
    24121 aagataataa gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt
    24181 cttttcttct gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc
    24241 ttgagcatcc acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc
    24301 agatacaagt cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata
    24361 cttttccatt attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat
    24421 tagtgtatta tctattatct atagaaaagg cagtatacct taattatact cttaatttac
    24481 aaaaaagtct taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca
    24541 ataacaccta ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa
    24601 atggtttgag gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat
    24661 ggtcttcctg caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt
    24721 caaaggcttt cattttatag aaaaagtcga tgagatgatc tgacaggtat tcagttgaaa
    24781 agggtacttc accacttttt cgatattcta ataagagtct agaaaatcga gctttttctt
    24841 caggaagctc acgaaaatag gaattgagga tccaagtctg cttctgtttt ctttcaattg
    24901 gatcctgact ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga
    24961 tagctcgttc tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag
    25021 tcagggtctc tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta
    25081 gaaccagatt gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg
    25141 cctggatacg gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga
    25201 gttggtcatc cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca
    25261 tccgagcctt tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga
    25321 aaagctggta gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt
    25381 tttcccagag ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt
    25441 cctttttctg agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt
    25501 ccaattgctg gtcaaggggc aatcgatgaa aatgacgaac acagtcgcta ccaattggaa
    25561 agaggcgttg gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttcgac
    25621 agacacaatt gctacggcca ataccgttaa aaatcaagga aacttcattc cattccttgg
    25681 tagcttgttc ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc
    25741 taactggaag tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta
    25801 gaaagctagc cgcagtcagc tcaaaacact gttttgaggt tgtagataga actgacgaag
    25861 tcagtaacca tatatacagc aaggcgaagc tgacgtggtt tgaagagatt ttcgaagagt
    25921 ataagttata cttttacaac ttgaacctcg tctttaccga gtaaaatcaa gtatttttca
    25981 atattttcaa tcgaataggc tcgtgataaa gcctcttcgt atagagctaa ctgaccacga
    26041 tagcggtcta cgagttgact tggttcatca tagcggtctg tcttgtagtc gaacagaaca
    26101 attttgtttt cgtaaagcag atagccatca aggataccac ggacaacaaa gtcttcctga
    26161 ctcttttggt ctcgtttgag catggagaaa ggttgctcgc gatagagatg gtcggtatta
    26221 gcaagaattt cctgaccgag tgctgtgtca aagaaagcaa gaattttatc aagattgatc
    26281 ttgtctctga cagcttggct agtttgaact tgtttgagtg tttctgttaa gctagcaagg
    26341 gttagttgct ggctgaggtc aattatctgc atgagttcgt gagtagcact accaatctca
    26401 gctccagtta ccttttcttt ggttgaaaaa tctggcaaat cgaagctgat tttcttgcct
    26461 actgactgac cttgaccagc aatctcgaca ccttccatat ccataactgg ttcgtagaat
    26521 ttcttgattt gacttggggt ttgaacacta ggaagttcaa tagctgcgcg gtgaagagta
    26581 ttataaactt ccacctcctt cagcatttcc agagcttctt tgatggtatc tgactgacga
    26641 ttgtctgctt gggagctatc ttggagagga ctcttggttt ccaactctcc gatagcttct
    26701 ctggtcaact gatcttcgtc aataaaacga taactaaagt tgagcttgtc cttagtaaac
    26761 actttactga tagcccaaag ccaatcttgg aaattccgtg cttgcagtct agtattgcta
    26821 tttagtttcc catttttggc tgctgggtat tccttggatt ccagcttttc acgagaaccc
    26881 ttgccgacaa gatagagctt tttctcagcc cgcgtcatag caacatacag caaacgcatc
    26941 tgctcagaat agcttgctag ctgtaattcc tcttcgttct gcctataggt cagactagga
    27001 atggagagtt tgatggtttt aggatagtgg tcttctactg cccctgtctc catcttggca
    27061 atatatttga caccaagacc attctgacga ctgagaatga cttctgacat agagtcttgc
    27121 ttgttgaaat tttgatccat attgaggata aagacgtaag gaaactccag ccctttactc
    27181 ttgtggatgg tcatgagctc tactgcatct tttggcggtg cgacggccac gcttgccaaa
    27241 tcgtgctggg cttctaagac ttggtcaatc atacgaataa aacgcgacaa acctttgaaa
    27301 ttgctctttt caaattgatc agcacgcagt gctagggcat agagattggc ctgcctagca
    27361 ggaccattcg gcaaagcccc aacatagtca taataaaaac ggtcgttgta aatcttccaa
    27421 atcaagtcat agagagagtg ggttttggca tacaagcgcc aagaagctag gatatccatg
    27481 aattgcttta gtttttcaac tagagctgtg tgaatcaagc ctttttgact acttgccatt
    27541 ttttgtgcat tgaccagttt ctcatagaga ttttcgtgga ctttatcctc tgctttctga
    27601 agggacaaac gtgctagctc atcctcatca aaaccaaaca ttggagactt cataagggca
    27661 accaaggcgt agtcttgcag gggattgtga atgacacgaa gagtgtctag catgacttgc
    27721 acttctaggg attggagata attgttttgc tctccgtcag ttttgacagg aatcccgtac
    27781 tcagacaggg cgaggagaat ctggtcatta cgactgcggc tggaggtcag aagggcaatt
    27841 tccttaaagg caacaccttt ttcttgatga agtttcagaa tctccttgat aactaagcgc
    27901 atttcgcctg ttagtttcgt ttctgtttga ctctcttctt cctcacctgt atcgtccttg
    27961 tcgtagagga gaaattctgc cttgttgtct ggattgggag tcagtttggt attggcaaaa
    28021 acaagctggt gcttgttatc atagttgatt tcaccgacct cttggtccat gagacgttca
    28081 aagacatcat tggttgctga cagcacttct gaactactac ggaaattttc cttgaggaga
    28141 atgagcttgc cttcttgggg attttgcgca tagcgttgga atttctcatt gaaaatctgc
    28201 gggtctgcct gacggaaacg atagatggat tgcttgatat ctcccaccat aaagcgattg
    28261 tggccattag acaacaattc cagcatccgt tcttgaatat ggttggtatc ctgatactca
    28321 tcgaccatga cttcatggaa gcgctcctga taagactcac gaacttgtgg gaaattctct
    28381 aaaatctcaa tggtgtaatg gctgatatca gcgaattcaa aggcattttc ctggcgtttg
    28441 cgctgacgat aagcctccac aaaatgactc ataaaggttt ggaaggtttt agctagtttc
    28501 catgtgtctt gatgataacg ttcttgatag tcgagaatgg ttatctggtc tgataattgt
    28561 cctagtttag caaactgggt ctttctctct tcgttgtagg catcagccag gggcttcaaa
    28621 tcagccttac gactggcatt agtcagagct cgaccgtttt tctccttaga gatggcgaca
    28681 acacgcgcaa gcactgcctg ataagcctga ctatcggact cctgatttag ggagcaaatt
    28741 tcatccagaa ttaactgaac attttctaaa taggcagcct ttgcaaactc cttggcatcg
    28801 ttatccagat ggtaacggaa aaagctttcc aaatcccaaa gggcttgttt gatttgctca
    28861 gtcagttttt ctttttcact ggtaaaatca gctttctcaa atcctttgag gaaagattca
    28921 ctcagccact tttgaggatt actggtggat tggaggaagt catagatttt atagacctgc
    28981 tggcgcagac cccgttcgtc cttgccacgc ccagcaaagt ttttcagcaa atgactaaag
    29041 gtctctttct gtttaccttg gtaatgcgct tcaaagacct catgaaagac ttcgttttcg
    29101 agaagaagtt gctcgctttg gttttgtaaa atacggaaat taggtgcaat atcaagcaga
    29161 taaccatgtt tgccaaggaa tttttgtgtg aaagagtcca tggttccgat ggcagcgttt
    29221 ggtaggtctg ccaactggcg tcccaagtgt tgtttgaggt cgacatcatc tgtttcttgg
    29281 attttcttgc tgattttttt ctctaaacgt tctttaagtt cagttgcagc cttgacggta
    29341 aaggttgaga taaagagttg agaaatttcg acaccacgcg ccaattggtc cagaatgcgc
    29401 tctgccatga caaaggtctt tccagaacca gccgatgctg agaccaggat attctgacca
    29461 gaagtgtaga tagcttcgat ttgctcggca gttttctttt gttccttgct cgaatttgct
    29521 tctgcttctt gcagtttttg aatctcctcc tcacttaaaa agggaataag cttcatcgat
    29581 tcaactcctc tcttattttt tcaagccaag cttgcttgag tttttctccg accagacgct
    29641 tgccatcagc taggtccaac ttttctagga aacgggcttg gcccagatgg taattggctt
    29701 caaagcctgt aatagcctga tgttgctgga cgtatggggc aatgcttctg ccattttcag
    29761 tataaggatt gatggcgaac cggcctgcta aaatcttctc agcagctttc ttgtaaagat
    29821 aggcattgta gtccagtagg agctgaaatt cctcatctgt cagttgattc gccttgtttt
    29881 tgttataaaa ttcgcctaaa taactgcttt ctttttccaa gaagagccct tggtatttca
    29941 tagatttgct ggcttctacc actgctcctg ccagactttt taccgccatc agagattgga
    30001 caggttcagc catttccaag tacatggcgc cgaaaaagtt ctgctcccct tctcttttta
    30061 gggcagcaag ataggttggt aactgagaat tgagcccatt aaagaaatga ggaaactgga
    30121 actgagtcag actggatttg tagtctacta ctcctatcgc tccattagct ttcaaacggt
    30181 caatccggtc caccttgcct cgtacaaaga cactgcgtcc attgtctaat tgaataaagg
    30241 cttggtcttt tccaccaaaa tttgcttctt ctttgattgt ttcgatggct ggattgtgtc
    30301 ggagaatatg tccagttgtc cgtgcaacat caagcaaaac ttccttggta aactgggctt
    30361 ccaaactttc ttgataaata gcttcaaatt cgcgttcttg actggtttct tgaatagctt
    30421 gttctagacg ttggtcaaag gaatcttcat taggcaactg caaggcgcgt tcaaagatac
    30481 gatgcaagaa attcccgtga ctacgggcat caggacgcaa acgtaattcc tcctgcaagc
    30541 ctaaaacgta gcgtaggaaa taactgtatt cattgcgata aaactctgtc aaacccgacg
    30601 tagacaggta aaactcctgt ttggcaggat agagagcttg caaggtgtcc ttggctaagg
    30661 tcttgctgct tggactgatt gggatggctg gattttccag accttgctga tctagttttt
    30721 tacctatgac acgcgacaga accttgacaa aagtcaaatc ttgctcagta tcgctcatct
    30781 caccctgctg gtgataggca accagactag acaaaagact gtgataggac cccatatcct
    30841 ccttagacag tcctttgtga ttcatcctct tctctctccg cctaaatcca aaatggatca
    30901 actcttgaag ataggcagat tccttacttt cactttcgtt aaaaaggctt ggagccgaca
    30961 agaacaactg cttacgagca gaattgacca aggaaagcat agtgtagcga tttttcttga
    31021 gattttcact gctggcaatc agtaattgaa cgccttcttc ggtcgtttgg tttaggtttt
    31081 gcctttcttc atctgtcaga agactggtgt tttgagaaat ttttggtaaa ttgtcctgag
    31141 ttagtccaat agcatagaca aagtcagcag tcaatggtgc aatcaaatcg taactctgca
    31201 ccagaacagt gtccactgtt gctggaatgg tacggtattg ggacaaactc attccagaat
    31261 ggagcaaggc taggaagtct tccagactaa cctgtgaacc agcaaaaaca gtcgcaaatt
    31321 gttctaaaac atggcagaaa gccttccaaa cttcggcttg tctttcctgt tctacagctt
    31381 ccaaagtggt tgtcaaatct tgtaactgct tggtcacagc tccttctttt agaaagacac
    31441 tccatttttg taggaggttt tcagcctttt gttttcggct ggcaaagagg gtttcaagag
    31501 gtgctaaaat tctcaggcgg aggacattca aacgctcaag attaaatttt ccatggtggg
    31561 atttggtgaa agtttgctga aaggctggca agccattgat accaagatag cggatatatt
    31621 gctcaaaagc atcaatatca gactgactga ggtcagtata caaatcagtt ctaagaagat
    31681 taatcaaatc ctcctgacga aaacggtaac gttttaaagc taaaatagac tcgacaaact
    31741 gagtcaaggg atgatgagcc atggcttcgc ttctaccaag ataaaaagga atctgatact
    31801 ggtcaaaaat ggttttgaga gataactggt aagaagctac atcccccaag agaatacgaa
    31861 aatgcttgta gctcaggtct gagttctcat gtaatttctg acgaatgcta cgggctacta
    31921 gctccaactc ctccttttgc gtcaaacaag accagatttg taaattttca cggtctttct
    31981 catcgacatc caaagcgagt tctgaaaagt cataagaaga ctccaacaaa cgagaggcct
    32041 tgtcaaaact atccatcttc tcatgagttt gagaacagtc ctgagcaggc gtttggtatt
    32101 tagaagccag atgatggaga aattttacgc tggcttggta gagattgccc tcgctaaaag
    32161 gactggtata ggctttctta ctagcataag ccccgataac aatctcaaca cctttgccgt
    32221 gaagtaagtc cacaacccgc tcttcctcag cagaaaaacg agtaaagccg tcaatgacca
    32281 aggtgatttg attaaaatca ctacttacct tgtcattctc aatagcctca atcaaatggg
    32341 acaactgact tccctgggct aactgacctt gattaagata ggctgttact ttctcaaaaa
    32401 tcaagagtaa atccgccctc ttatcctcat ctgttaaatt ctccaagtcc aaaaaactca
    32461 tctgagattt ggtcatctca tggtaaagct caattaactg ctggatcaat tgaggatcct
    32521 gcttaatagc gccataaaca cgcaagtcct tgggatcgag ttcggcaagg catttgtaaa
    32581 aggccaaccc aagaccgata tcatcaagag tagttttaac tggtaaatca ttcaagacca
    32641 gataacgagc catttgagca aagcgcgtga cggtaatcga aaaagaagcc tgctgggaca
    32701 agcattccag cacggcgcgt tccttttcaa aagaaagaga gttgggggca atgtagaaga
    32761 cccgcttgcc agctgcaact agctcttctg cctctcttgt tagaatttct gtcaaagaag
    32821 ttcgaatatc agtataaagt aatttcatct cagcctcgtt ggaatttttc atcaccctat
    32881 attataccat gattagcctc gtaaatctgt taaaatattt aggccatcct ttcttttctt
    32941 catcatctgc taaatcttaa atacttagct ttacttgtat tagatagaat aagtctggct
    33001 actgaaaatc acataataaa aaagcctcgg taacaaggct ttgagtttta tgattgtttc
    33061 ttaggtacgg aatacacttc aatgtgttgt cccagtatct taatgtcgac tggtagattg
    33121 tctgatttat cgccatcaac atcggactct aattcgatat cagaagaagt tttaatatta
    33181 cgtgccttta tatattcaat attcttgata gaatgattga actatagtaa attgaaacta
    33241 taatagtaca ccgtggatgc taaaatattt ctagaaatta atttgatttc cctaatcaag
    33301 ctgttcgtat cttatttcaa tcta
//
LOCUS       DAVAZV010000018        32938 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVAZV010000018 DAVAZV010000000
VERSION     DAVAZV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.018"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(361..1050)
                     /gene="rplA"
                     /locus_tag="VQT46_000841"
     CDS             complement(361..1050)
                     /gene="rplA"
                     /locus_tag="VQT46_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET2370893.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMGLVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(1257..1682)
                     /gene="rplK"
                     /locus_tag="VQT46_000842"
     CDS             complement(1257..1682)
                     /gene="rplK"
                     /locus_tag="VQT46_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET2370894.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAVRMIEGTARSMGFTVID"
     gene            complement(1805..2521)
                     /locus_tag="VQT46_000843"
     CDS             complement(1805..2521)
                     /locus_tag="VQT46_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET2370895.1"
                     /translation="MKKRYLVLTALLALSLAACSQEKAKNEDGAAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     VIGTNGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYFGFEGGDYVD"
     gene            complement(2524..2994)
                     /locus_tag="VQT46_000844"
     CDS             complement(2524..2994)
                     /locus_tag="VQT46_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2370896.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVSELHHLEKKTRIRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     RGDMNGYGLNGRGPVWWIPFEEMTAEICQSKPDEIKRLVERLSSEVDKLLEIKE"
     gene            complement(2996..4033)
                     /locus_tag="VQT46_000845"
     CDS             complement(2996..4033)
                     /locus_tag="VQT46_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET2370897.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVLGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAMLLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTNEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSALVD"
     gene            complement(4131..5456)
                     /gene="brnQ"
                     /locus_tag="VQT46_000846"
     CDS             complement(4131..5456)
                     /gene="brnQ"
                     /locus_tag="VQT46_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET2370898.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(5627..5719)
                     /locus_tag="VQT46_000847"
     CDS             complement(5627..5719)
                     /locus_tag="VQT46_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2370899.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(5762..5914)
                     /locus_tag="VQT46_000848"
     CDS             complement(5762..5914)
                     /locus_tag="VQT46_000848"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET2370900.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(6074..6652)
                     /locus_tag="VQT46_000849"
     CDS             complement(6074..6652)
                     /locus_tag="VQT46_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET2370901.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPCT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(6706..8106)
                     /gene="pepV"
                     /locus_tag="VQT46_000850"
     CDS             complement(6706..8106)
                     /gene="pepV"
                     /locus_tag="VQT46_000850"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET2370902.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(8119..8724)
                     /locus_tag="VQT46_000851"
     CDS             complement(8119..8724)
                     /locus_tag="VQT46_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET2370903.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDLKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            8895..9695
                     /locus_tag="VQT46_000852"
     CDS             8895..9695
                     /locus_tag="VQT46_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2370904.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(9877..10710)
                     /locus_tag="VQT46_000853"
     CDS             complement(9877..10710)
                     /locus_tag="VQT46_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2370905.1"
                     /translation="MNHKIAILSDIHGNATALEAVIADAKTQGASEYWLMGDIFLPGS
                     GANDLVALLKELPITASVRGNWNDCVLEALDGQYGLEDPQEIQLMRMTQFLMERMDPA
                     TTVWLRSLPLLEKKEIAGLRFSISHNLPNKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNIQFRKV
                     AYDYEAELELAKSKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDF
                     L"
     gene            complement(10700..12547)
                     /gene="uvrC"
                     /locus_tag="VQT46_000854"
     CDS             complement(10700..12547)
                     /gene="uvrC"
                     /locus_tag="VQT46_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET2370906.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGIHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDTKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGRPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRAVAEAVQRKLNPQETEILLQVAEERVDYQTEGNHNKP"
     gene            complement(12587..13288)
                     /locus_tag="VQT46_000855"
     CDS             complement(12587..13288)
                     /locus_tag="VQT46_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET2370907.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKMGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(13367..14599)
                     /gene="murN"
                     /locus_tag="VQT46_000856"
     CDS             complement(13367..14599)
                     /gene="murN"
                     /locus_tag="VQT46_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET2370908.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSEYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(14604..15824)
                     /gene="murM"
                     /locus_tag="VQT46_000857"
     CDS             complement(14604..15824)
                     /gene="murM"
                     /locus_tag="VQT46_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET2370909.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRTSKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(15936..16715)
                     /locus_tag="VQT46_000858"
     CDS             complement(15936..16715)
                     /locus_tag="VQT46_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET2370910.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIRDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(16784..18445)
                     /locus_tag="VQT46_000859"
     CDS             complement(16784..18445)
                     /locus_tag="VQT46_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET2370911.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKILSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEDYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(18620..20842)
                     /gene="recJ"
                     /locus_tag="VQT46_000860"
     CDS             complement(18620..20842)
                     /gene="recJ"
                     /locus_tag="VQT46_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET2370912.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKTYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            21119..21877
                     /locus_tag="VQT46_000861"
                     /pseudo
     CDS             21119..21877
                     /locus_tag="VQT46_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            21917..22681
                     /locus_tag="VQT46_000862"
     CDS             21917..22681
                     /locus_tag="VQT46_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET2370913.1"
                     /translation="MISLFGLAAAKPVQADTSIADIQKRGELVVGVKQDVPNFGYKDP
                     KTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIATFTITDERKK
                     LYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITELGKKKGLKFK
                     FVELGSYPELITSLHAHRIDAFSVDRSILSGYTSKRTELLDDSFKPSDYGIVTKKSNT
                     ELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            22694..23371
                     /locus_tag="VQT46_000863"
     CDS             22694..23371
                     /locus_tag="VQT46_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2370914.1"
                     /translation="MIDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILAHIFVEFYQNTPLLVQFVIVFYGLPLISDHTIMIPIYWTAVLCMGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQTFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            23381..24040
                     /locus_tag="VQT46_000864"
     CDS             23381..24040
                     /locus_tag="VQT46_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2370915.1"
                     /translation="MESILEVLTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPVLRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNTVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLCILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            24335..25525
                     /locus_tag="VQT46_000865"
     CDS             24335..25525
                     /locus_tag="VQT46_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET2370916.1"
                     /translation="MKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(25846..26727)
                     /locus_tag="VQT46_000866"
     CDS             complement(25846..26727)
                     /locus_tag="VQT46_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET2370917.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(26868..28196)
                     /gene="vncS"
                     /locus_tag="VQT46_000867"
     CDS             complement(26868..28196)
                     /gene="vncS"
                     /locus_tag="VQT46_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET2370918.1"
                     /translation="MKRTGLFAKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGATMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(28193..28849)
                     /gene="vncR"
                     /locus_tag="VQT46_000868"
     CDS             complement(28193..28849)
                     /gene="vncR"
                     /locus_tag="VQT46_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET2370919.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASIAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(28898..28981)
                     /gene="pep27"
                     /locus_tag="VQT46_000869"
     CDS             complement(28898..28981)
                     /gene="pep27"
                     /locus_tag="VQT46_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198524447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET2370920.1"
                     /translation="MRKEFHNVLSSGQLLADKRPARDYNRK"
     gene            complement(29161..30540)
                     /gene="vex3"
                     /locus_tag="VQT46_000870"
     CDS             complement(29161..30540)
                     /gene="vex3"
                     /locus_tag="VQT46_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET2370921.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(30592..31239)
                     /gene="vex2"
                     /locus_tag="VQT46_000871"
     CDS             complement(30592..31239)
                     /gene="vex2"
                     /locus_tag="VQT46_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET2370922.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKDTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(31252..32529)
                     /locus_tag="VQT46_000872"
     CDS             complement(31252..32529)
                     /locus_tag="VQT46_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2370923.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITSYLLQTLLASGDQASLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9296 a         7546 c         6117 g         9979 t
ORIGIN      
        1 attgaaacta gaatagtaca tctcttcttc taaaacattg ttagaaatcg atttggctgc
       61 cctgatcgat tcgtcctact cttatttcat tttactataa ttgatagtgg tcgccccagc
      121 cagatacctt atccgctata taggccttat tatcatgttc ctgttcgtag agccacgatt
      181 tcgctatccc ttcctctgac gattcttatt tcctgcgtca gacttgggaa tcgctattgg
      241 gttcaccggt agcaggtgcc caccgaggac ttacacctca gatatacgac atgcccgtcg
      301 tacatcaaaa aaagttgaga catagcgtct tcaacttttt tacattactt taactactga
      361 ttaaagtgag tttacgtcaa ctttgatacc aacaccttga gtagttgtga tagtcaagtt
      421 tgttacgtaa gttcctttag ctgtagctgg ttttgctttt tggattgttt cgttgaaagc
      481 tttaaagttt tcaaccaatt tttcagcttc aaatgatact ttaccgatga ttgcttgaac
      541 gttacctgca cggtcagcac ggtaagtgat tttaccacct ttagactctt caactgcttt
      601 agcaacatcc attgttacag taccagtttt agggtttggc atcaagttac gtggtccaag
      661 gacacgtcca agacgtccaa caagacccat catatcaggt gtagcgataa ctacgtcgaa
      721 gtccaaccaa ccgtcgttga ttttagcaac aaggtcatct tcaccaacaa agtctgcacc
      781 agcagctttt gcttcttcag cttttgcacc acgtgcgaaa acaagaacgc gtgaagtttt
      841 accagtaccg tttggcaata ccattgctcc acggatttgt tgatcagctt ttttaacgtc
      901 gatgttcaag ttgtaagcaa cttctacagt tgcgtcaaat tttgcaaagt ttgtttcttt
      961 tgcaagtgct acagcttctt ctacgctgta tgcttttgtg ctgtcgattt tctcaagagc
     1021 agcacgaagt tgtttgcttt ttttagccat tttctattct ccttgtaagt ggttcaatcg
     1081 attttcatct cccacgtcac ttctcgaaat gatgaagtct tgcgggtttt cagtctatta
     1141 gattcttttc ctacggcctt aagctccctt gctgtaccca agtacaagca tcagtcactt
     1201 gcctagtatg aaaagcaact aatagactgc tgtgagattt tctactgtgt tattgattag
     1261 tcaataacag tgaatcccat agaacgagca gtaccttcga tcatacgcac tgcagactct
     1321 acgtttgctg cgttcaaatc tggcatctta gtttctgcaa tttcttgtac ttgtgcacga
     1381 gtaactgtag caactttagt tttattaggt gtacctgatc ctttttcaac acctgcagct
     1441 tttttcaaaa gaacagcagc tggtggtgtt ttcgtaacga aagtaaatga tttatcttcg
     1501 taaactgaga taacaactgg aatgatcata ccagcttggt cagctgtacg agcgttgaac
     1561 tcttttgtga atcccatgat gttgatacca gcttgaccaa gagcaggtcc aaccggtgga
     1621 gctggtgtag ctttaccagc agggatttgc aattttacaa gtttttcgac ttttttagcc
     1681 atttttaaat cctcctttgt ggttttggcg gtaattagag atttttacct cccacaagta
     1741 tgtttttcac atacccatct attatacact atttatctgg aattgcaaga gaaaagttta
     1801 ttttttaatc gacgtaatct ccaccttcaa agccgaaata ctcttccaaa ctgaggccac
     1861 tagctgcaat ctctttagcc tcttttccga cataacgaag gtgccattcc tcagccatat
     1921 agcctgtttc cttttcctta cctttgagat aacgtacaac aaagccataa tcagccgcat
     1981 gatccaagag ccattgggcc gctttttctt ctgtcaccaa atcaccattt gtcccaatca
     2041 catcaaaggc taaacctgtc tggtgctcgc tatagccagg acgggcagaa taacggtcgg
     2101 cagcttcttt cccatcttga ttgacataat cttgatagag cttggtctga gtttcataac
     2161 ttctaaagcc actgtaatga tcgctaatgg ggaaacctgc ctcttgcata gctttgatga
     2221 gcttgaccaa ctcagccttg gctgttggat tttcccctgg attgtagtct tttgacaatg
     2281 gatagtgttt gttggctacg atgatttcat cgtatttccc ttgaatgctg taatagtctc
     2341 ctttgttaac cacttctgct tttttctggg cagctccttg agacttactt cctactgttc
     2401 catcagcttt agcagtttgc tctgtcttag ctgctccatc ttcatttttt gctttttctt
     2461 gtgaacaagc tgctagactc aaggctagca aggctgtcaa gacaaggtat ctttttttca
     2521 tctttactcc tttatttcta atagtttatc tacttctgat gataaacgtt cgactaatct
     2581 tttaatctca tcaggttttg attggcagat ttctgctgtc atttcttcaa agggaatcca
     2641 ccatactgga ccacgtccat tgaggccata accattcata tcacctcttc gtctaggaaa
     2701 cagatgccaa tggagatgag catcgccatt tcctagtagt tcgatattca ttttctcagc
     2761 agcaaaggcc ttggcaactg cctcttggac cacactcatt tcttctagaa aacgtattct
     2821 agttttcttt tctaaatgat gcaattcgct gacatgttcc ttggctagaa agagactata
     2881 gcctgcaaaa tactggtggt ctccaatcac aagatagcct gtttccaact ctttgacaaa
     2941 atagggattt tctcccttct tgatgagctc aattctctgg caaatcaaac acatattagt
     3001 ctaccaatgc actcttaaga taggcatcga ccattcgttc tgttgcgacc accgagtcaa
     3061 tatgagtgcg ctcataagaa tgactagact cgatacccgc accaagaagg gcatgcttga
     3121 cctctgcccc tgcagacata gccgctgaag catccgaacc ataaaatgga tagatgtcca
     3181 gcttaaaagg aatatcttgc tctttagcca aggcaaccaa gtgttgacgg aagtcatagt
     3241 gataaggacc tgaggcatcc ttgacacaga tagatactgt gtactcattt gtctgctggt
     3301 catctcccat agctcccata tccacagcca gatattctac tacctgagca ggaatgttag
     3361 aattagcacc atgtcctact tcttcaaaaa ctgaaaaagc aaaatgagtt gttactggca
     3421 attcaatctt ctctttctta taaatacgaa gcaggttgag caacatcgct gcgctgacct
     3481 tatcatccaa atgacgagac ttgataaaac ctgtatcagt cacaacagtt cgtggatcga
     3541 agctgataaa atcaccgacc tcaatcccaa gagcacgagt ttctttttca ttgcttactt
     3601 ttacatccaa acgcacttcc atattgtcct gcgtgcgttc tgcagttcct gcatccttgt
     3661 agacatggca agaagtttgg tggatgagga tggttcctaa taccttttga cctgtgctag
     3721 ccacatgaac ggtacagttt tcaccttcaa tcatgttcca aggaaaacca ccgatacggt
     3781 ccaatttaag acgaccatct ggtttgacag cacgaacaat agcacccagt gtgtccacat
     3841 gggcagtcac atagcgatgt tgctcatcat tttgaccttt gatggtcaca ttgacaccac
     3901 ccttggctgt gcgaactggc tggtaaccaa aaccttctag agtcttgact aaataattcg
     3961 aaatttcacg agtgaagccc gttggcgatg cgatggctgt cagttctttg atatattcta
     4021 ctgtttgatt catttcttca cctctttcgc tacctattat aacacattta tcatcggata
     4081 aaaaaagaaa atcactcctg tagacttggc tacaaaagtg atttaagtga ttattccatt
     4141 tcaaaaacat cgctttcttg cttgtttggt agaaccaatg agagcaagat tccaacaatg
     4201 gctggcacca accatgggag agatgccttg gcaaaaggaa gaacgctaac aagatttgca
     4261 agaaactcaa ccttaaacga gcttcctagt acgcttgcaa tggcaataac tgtaaccaca
     4321 gcaattgtca actgcatacc tggttttgaa agggcaacaa atttgttgac aatgacaatc
     4381 ataacgatag caatcgtgat tgggtacaag ataaccagta ctggaattga gtacttgata
     4441 atcgcatcaa gacccaaatt ggcaatagca aatccaatca aggtaaaggc tgtcgcataa
     4501 accttgtagc tgatttgtgg gaagcgctca ttaaagaact cagctgttga cacaatcaaa
     4561 ccaacagtcg ttgtgaagca ggttacggta accatagctg caaggaagag ttgagctgtt
     4621 gagccaaaga tttcttgagt ggcttgtgac aagatgtaaa cacctggtgt tccacccttc
     4681 atcgcttcag ctggtactgg gaaatgattt ccaagaaaac ctaaaccgat gtaaagagcg
     4741 ctgaaggcaa gggcaacaac gataccaaca acccaaatag ttgaaatgta ttctttctta
     4801 cttgaaaatc caagttgttt caaggtttga actgcgatta cgctaaaggc cactgaggca
     4861 agggcgtcca aggtattata accttctagg aaacctgtac caaaggcaga agcttgataa
     4921 gcagctgaag cagcttgagg acttgttcca ccatatttga tagctcccag aacgaccaag
     4981 ataacaatca aaattgcaaa gactggcgtt aaaatacgtc caatgcggtc taagattttt
     5041 gatggattaa gcgaaatcaa ataggctgcc gcaaaataca gaaccgtaaa tacaatcaag
     5101 ccaagtcctt tatttgcatc cgacaaaagg gggctaatcc ctacttcgta agctgttgta
     5161 gcagtacgtg gggtagcaaa gaatggaccg attgacaagt aaagaactga gaggtaaaga
     5221 gtcgcaaacc aaggcgctat cttcgttgaa atctcgtaga tatatccttt aggatttagc
     5281 gttccaataa taagggtcaa gacggcgata ccaacgcctg aaaagacaaa acctgcgatg
     5341 gcaggaagaa aatgttctcc agatagagca cctagagaag gcggaaaaat caagttcccc
     5401 gcaccaaaaa atattccaaa caggagcaaa cctgttaggg tacctttttt agccataaaa
     5461 atctccttca tatttataaa atactgatct agtataccac gattaggagt ctgaaaaaag
     5521 catcacgagg caaatattaa atgttttcaa ttttcttaaa aataagaatt atctaaaaat
     5581 aaaactctcc tacccagtcc acaccaagta ggagaaatgc aaaattttaa agttcttcaa
     5641 aggctaacat gccaccctgg acattgataa cattataacc ttgttctaat aggaattggc
     5701 aagcacgcgc cgatctcatt ccagatttgc aaataatata atgcaagcga tctttgtcca
     5761 attaatcata actatcagcc aattgactaa gcggtaggtt gtgggcacct tctaaatgaa
     5821 gagctgcaaa ctcatccact tctctcacat ccactagaga aagctggtcg ttttggtaaa
     5881 gctggtaaaa tgcgtcaaag gctatttctt tcattctttt tcttctaata ctcttcgaaa
     5941 atctcttcaa accacgtcag cgtcgcctta ccgtgcgtat gttaccgact tcgtcagttt
     6001 tatctgcaac ttcaaagctg tactttgagc agcctacgac tagcttccta gtttgctctt
     6061 tgattttcat tgactataaa atggttttaa ttcttttttt caaatctggc actacttctg
     6121 cctcaaacca aggatttttg gccatccaga tttgatttcg tggtgatggg tgaactagcg
     6181 gaaaataggc tggcagatag tctttatagt gtttcaccct ctccgttacc ttcccactga
     6241 ttttctcctg taaatagtag gcttgggcat attgcccaat caagagggtt aactgaatat
     6301 caggcaattc ctgtaagagc tgcggatgcc atttttctgc aaaacctgta caaggcggaa
     6361 gatcacccga cttgccatgt cctggaaagt agaaatccat aggcaaaaca gcaaaataac
     6421 ctgaattgta aaaggtatct tcatccacac ctagccagtc ccgcaaacgg tcaccacttt
     6481 tatctttcca gtaaaggcct gcttcttgag ttttaagtcc cggagcctga ccgatgatat
     6541 tgatgcgagc agtttttggc gctgcaaaga gaggctcaat gccacgctct gtatagctgg
     6601 cattctgcga atccgccatg atagcctgtt tgattctttc gatttgagac atctactttc
     6661 cctccaaaaa gaagtccaag cataagatct cagacttcta tcgttttatt tgatcaattc
     6721 gtaaatagct tcggcataaa ttgctgctgc tcggaagaga tcgtccaagg caataaattc
     6781 attggcttgg tgcatggtat caattgagtc tgggaacata gcaccatagg caactccgcg
     6841 ctctaacaag cgaccaaagg ttccaccacc gatgacttgt tcatgacctt taaggcctgt
     6901 ttgtttttca tagacattca acaaggtttg cacaagtgga tcttccattg gcacatagtg
     6961 aggggtatga ccatgttctg atagactgac agaagcaact ggcaagtttt ctaggattga
     7021 cttgatttgt tctggacttg ttccttttgg atagcggatg ttaagggcaa tggtattatc
     7081 agcacttgtt tcatcgaagc ggaagacgcc ggcattcata gaaagagcac ccatcttttc
     7141 atccacatga gcaatcttga gattttcacc ctcatgatcg ttcaagagaa ttttacctgc
     7201 gatgtcaagg tagtctttgg ctggaccagc aaagccaaac tggctgagga agagggcaag
     7261 gtaagttgcg ccattgacac ctgaagcagg catagcaccg tgggctgatt taccaatgat
     7321 cgtcaccttg tattggccag cttcttcttg gagttctcct ctaagtttgt gttctgcaac
     7381 aaaggcatct agtttagctt gcaagtctgt caagtcacct gaaacgactg ctgttgctga
     7441 ttctggtacc atattttcac gtaaaccacc tgtaaagctg tgaagacggg ctgcacctgt
     7501 attttcacct gcaaagtgga ggtattccgt gatgtttcct ttttcaccat tgatgattgg
     7561 aaattcagca tctggtgaga aaccaaagtc tggcttggcg agtcctacgt gctcgaagta
     7621 gtagtccata tctgcccagc ctgattcttc gtctgttcca acgatgaagc gaactttctt
     7681 agaagttgga aggcccaatt ctttgatgat tttcaaacca tagtagcaag ctgttgtagg
     7741 tcccttgtca tctgaagcac cacgcgcata aaggcgacca tctttgatag ttggtgtgta
     7801 agggtctgtg tcccaaccgc taccagctgg aaccacgtcc atatgggcaa agattccgag
     7861 aacttcttct ccatcaccaa actcaaaatg tcctgcatag ttatcaacat ttttagttgg
     7921 ataaccatca cggtctgcga tttcaaggaa tttttccaag gcttttactg gaccaggtcc
     7981 aaatggatgt tgggcatcag ccttgctatc atcacgttct gagttgattt ccaaaaggct
     8041 aaacaagtca gccaagaggt cttctttgcg tttttctact tctgctgtaa aatcaattgc
     8101 tatcattttt tcttcttcct atcttttttc gatgatttca tctactggca agcggtagct
     8161 tggttccaat ttgtcgtctg tgtaacccac tgtgatcaag agttctgggc ggaaacggtc
     8221 ttcaatttcc aaaacctcat tgacttttga tttgtcaaaa ccaaggataa tattggaacc
     8281 aattccttgg tctgtaagag cgagaaccaa gttcatagca accaaacctg cattgagtgc
     8341 taggtagtcg ctgacttgtt gttcattgta gcgtgcaaat tcagctggca aatttttcat
     8401 gaagtattga agttgttctt ctgagaaatt gttagcacca ccaactcggg caatcttacg
     8461 agcgcgtttg gcaaggtctg tatctgtaaa tagggcaatg gttacaggtg ctgatgatac
     8521 ctgctcaaag tttgaaccat aagccaactt tgccagttca gcatttttct cacgaacaac
     8581 tacaaatttc caaggctggc tgttgtgggc gcttggcgcc aaggttgcaa tttcgatagc
     8641 cgtacgcaca tcttttagat caacaggctt atcagtgaaa tgcttggtcg catgacgttt
     8701 tttatttaat tcaagaaatt tcataatcga tttccttttc taattctact gcttccattc
     8761 taccataatt tgaaagagct tgcagggatt tttcatgatt aagtttttct atcacagaca
     8821 taaaagatat atattggttt atcaggaaag tttctgataa actagcaagt actttacatt
     8881 tgaatggaga cagtatgaaa aaatttagcc tattactagc tatcctacca tttttggttg
     8941 cctgtgggaa tcaagctaca cccaaagaga ctagcgctca aaagacaatc gtccttgcta
     9001 cagctggcga cgtgccacca tttgactacg aagataaagg caatctgaca ggcttcgata
     9061 tcgaagttct aaaggcagta gatgaaaaac tcagcgacta cgagattcaa tttcaaagaa
     9121 ccgcctggga aagtatcttc ccaggacttg attctggtca ctatcaggct gcggccaata
     9181 atttgagtta cacaaaagag cgtgctgaaa aataccttta ctcgcttccg atttccaaca
     9241 atcccctcgt ccttgtcagc aacaagaaaa atcctttgac ttctcttgac cagatcgctg
     9301 gtaaaacaac acaagaggat accggaactt ctaacgctca attcatcaat aactggaatc
     9361 agaaacacac tgataatccc gctacaatta atttttctgg tgaggatatt ggtaaacgaa
     9421 tcctagacct tgctaacgga gagtttgatt tcctagtttt tgacaaggta tccgttcaaa
     9481 agattatcaa ggaccgtggt ttagacctct cagtcgttga tttaccttct gcagatagcc
     9541 ccagcaatta tatcattttc tcaagcgacc aaaaagagtt taaagagcaa tttgataaag
     9601 cactcaaaga actctatcaa gacggaaccc ttgaaaaact cagcaatacc tatctaggtg
     9661 gttcttacct cccagatcaa tctcagttac aataacactc ttcgaaaatc tcttcaaacc
     9721 acgtcagctt tatctgcaac ctcaaagctg tgctttgagc aacctacggc tagcttccta
     9781 gtttgctctt tgattttcat tgagtataag atatactaaa agcgattgga ccagccaatc
     9841 gcttttttag tttgcattgg ctattttagg aaactcttac aaaaaatcaa aaaaattctt
     9901 cacatcctct acatacccat gcttttctat taagctggct aaaagttcca gattgtgccc
     9961 ctgatagtta tcgtcacgac gcagttcttc atacatttca ataaagggaa gccccttgga
    10021 cttggccaat tctaactcag cctcgtaatc ataagcaact ttacgaaatt ggatattgac
    10081 caattcccca tcttcaactt ctatcacggc atactgggca cggtgatttt ttaacgcctc
    10141 ccaattaaaa tagggcatgc caatcgaccc tggattgatg atttgttgcc cttgacttcc
    10201 ataacgaagc aactgcttgt gaacatgacc ataaactgcc acgtccgttt ccgcatctag
    10261 cagttggtca aatttctctg tatcattctc aactagcaag tcaccaccat agttcttatt
    10321 tggcaaatta tgagagatag aaaagcgcag tccagcaatt tctttctttt ccagcaaagg
    10381 caagcttcgt agccagacag tcgttgcagg atccattcgc tccatcaaaa actgagtcat
    10441 tcgcatgagc tggatttcct gtgggtcttc taagccatat tgcccatcta aagcctcaag
    10501 gacacaatca ttccaattgc ctcgaacact tgccgtgata ggaagttcct ttaacagagc
    10561 gaccaagtca tttgcacctg aaccagggag gaaaatgtct cccatgagcc aatattcact
    10621 ggctccttga gttttagcat ctgcaatcac tgcttctagc gccgtcgcat tgccatgaat
    10681 atctgataaa attgcgattt tatggtttat tgtggtttcc ttccgtttgg taatctactc
    10741 tttcttccgc cacttgaagc aagatttctg tttcctgcgg gttcaacttt ctttgcacag
    10801 cctctgctac tgctcttggt actccaactt cgacaatctc atccacactg gcttccttga
    10861 ttttggtcag agacttgaag tgcctcatga gattttgctt gcgtttaggt cccagaccat
    10921 caatcccatc caattgagat gagaaagaat ttttggagcg cagttggcgg tggaaggtaa
    10981 tggcaaagcg gtggacctca tcttgaatgc gttggaggag gaaaaattcc tgagaattgc
    11041 gagacaagtc caccacttcc agcggatctc caaagagcaa ttcatgggtt tggtgcttat
    11101 cattcttttg cagacctgca attggaatat ccaagcccag ttcttcttgg atgacttgct
    11161 tagcaatatt gacttgacct tgccccccat caatcacaat caaatctgga ggagtcaaag
    11221 cctcacgctg tactcgacca tagcgtcttc gaatgacttc tctcatacta gcatagtcgt
    11281 ccggcccaac aacggttttt atcttgtact tacggtaatc ttttttactt ggcctgccgt
    11341 taacaaagac caccatggct gaaacaggac tggtccccat gatgttggag ttatcgaagg
    11401 actcgatgcg aactggagtc ggaatttgga gcaaacgtcc tagattttca atagctcctt
    11461 gggtcttttc gactgatttt tctagcaggt taaatttctg ctccagacta acacgtgcat
    11521 tttttatggc tagattgacc agctgttttt tctctccacg ttggggtttg agaatcttgg
    11581 tatccaccaa agccttgaca gcttcttcgt caatatcctg cggaatcagt acctcattgg
    11641 gaactaggtg agatttttct tgatagaatt gtcccacata ggtcaagaaa tcctcatctg
    11701 gatcattgaa gtaggggaag agattgacat cgcgctcgat gagcttgccc tgacgaacaa
    11761 agaaaacctg cacacacatc cagcccttat ccacatagta gccaaagaca tcgcgatttt
    11821 ggagatcctt agccatgacc cgttgcttgg ttcgaagcgt tccaatagcc tgaatcaggt
    11881 cacggtattc cgccgcacgt tcaaactcca tactttgtgc tgctactgcc attttactct
    11941 tgagatcatc gatgattttg tcatcctgac ctttcagaaa atcagacacc tcctgagcca
    12001 tagacttgaa ataagcctca tccttcttac agatggtgtg ggccatacac tggccgatat
    12061 ggtaataaaa acagacctta gagggcgggt tggtacattt tcgaaaaggg aaaatcctat
    12121 ctagaagtcg cttgatttca ttggctgccc ccacatctgg ataagggcca aaataaagac
    12181 caccgtcctt tttgacctga cgagtaatga taagccgtgg atagcgctca ttggtgattt
    12241 tgatgaaagg ataggacttg tcatccttga gcatgatatt gtacttgggc ttattttcct
    12301 tgatcaagtt gatttccagc agaagcgcct caatattgga ctcagtgacg ataaattcaa
    12361 aatccacaat ttcagacacc agagcctctg tcttggtatc atgaattcca cgaaaatagg
    12421 accgtactcg attacgcaga tttttagcct ttcctacata gataatggtg ccatttttat
    12481 ccttatgaat gtagcaacca gggctggtcg gcaagagctc tagttttgat ttaatcaagt
    12541 tgttcatagt tccattatag caaaaaaagt agggaaagat agtaccctac tcactagtct
    12601 catatatttt tcggaggttt gcaacatcct cttcctggat accataaaag gaacctgctg
    12661 gttgcatgac agacttctca tctgtatggt ccaagccaat cgcatgacct aactcatgtt
    12721 ctgccgtatg gacaaggcgt tcataggagt agccatagta tggattggac aaataataat
    12781 gattcaaccg caccgttacg gacaagaatt gccctgttaa gagattagtt tgactttccg
    12841 cctctcctgc cacaggagtg cctccgtcgt tcatctccgt agccgtaata tccgccttac
    12901 tagactcagt cacgagttca aagttaaaag caccagtttg attccagttc tggattgctt
    12961 ctaaataagc ctcttgaaag cgtgaatcca tctgcggatc caggtaaata cgagcagagg
    13021 cctgtgccca ccttccttca gaatgctggt gactatctgt ctggcttaac ttaggcagtt
    13081 gccctgtttt ctcccattgg tcaatacttt gttgacccat ttttactgac cgttctgctt
    13141 gctttagcgc tccttgaaaa tccccgttca gataccagag aagtccgaaa gcaagcacac
    13201 ataagagcac aactatccaa accagacgcc aaaacaaacg ccacacaaaa gaaaagaaag
    13261 cccctatcaa acgaaaaagc cagcgcatgt ctctccacct ttctagcaaa taagaattat
    13321 tttactaaaa gaagctaaaa gaaatctaaa tactgacttt ttcatcttaa cgtcctacta
    13381 tttttttgag taactggata gctttgtatt ttaaaggcga tggatggtaa cggaaagtac
    13441 ctgctttgcg tacaatatag ccattaaaat tctgtttaaa acgcaaaaca ccatcacttc
    13501 catcaaaaat cccttgaatg cctaggaagt tgtatttagg tattccacgt tttatgcttt
    13561 ccaacataac atatttttga agcagtgcag gggcatagaa cttattaaac tcagtgtagg
    13621 aaccactaaa gagataagtc gtttcctgag gcatataaac aaataaactc ccagctaaaa
    13681 caatatcttc ttctccatat ttttcaatca agtctcgcgc ttctgctttt cgaacttcaa
    13741 acgtttcaaa ttgactagaa tattctctca gttgattttg ttttttctca gaatgaggat
    13801 ttttactcaa atcaagtcgc aacttgtcca agttttcttc tagtttactt tgttcacctt
    13861 gcaatttgct catatactcc gaaaaattca agcttgctat gagaaactcc gcttgttctc
    13921 caaaagtatc ataaaaatgc tcataatatt ctaaactttt atcactatat tctctacgtt
    13981 cagaggtttc ttttgttata ttcttaaaaa tcgatagttc ttcacgtttt aactttttca
    14041 accgaatgcc aaaggtttca gcctttttca ccaagggttt accctttttg ctaaaacttt
    14101 taagcaaact cttttcagtt aattcagtta aatctttata gtataaccaa tctggttctc
    14161 cacctgggta acctgttgtt aagccatcaa attgataacc taaatcagtc aaaccttgaa
    14221 taatactttt tttctcagca tctattggat taccttggct atcaaaagtt tgataagttt
    14281 cataaggttt tacaagcaac tctaatacac cattttgctt ggcatattct tttaactctg
    14341 cataaaaaac tggaagagca tcttgttggg tataaatcgg ccccgaattg agttccatat
    14401 gcagaccacc cagcatgggc aagctataaa ccagagctgc aacttgaatt tctccttctt
    14461 gtttcaaagc aagataaaca attcgagccc ctcttttttc tagcaaatcc cccatctgga
    14521 cagattgcat aaaggaacga gaagaaacct gatcagaata agtctgaaac tcttctttcg
    14581 tgagtgttgt tagtgccata tacttacttt ctatgttttt ttcttaatgt tttacggaaa
    14641 tcaagagcaa gtcttaacag aggatagaga ggatgagtgg gcattgtaaa ttcacccaag
    14701 tattcttcaa tcgttggatt aaatttttcc ttaaaatgat aaagtccacc attgagagag
    14761 ttttcaacac cacctaaatt ttgccagacc atacctcgct caaaggcata gcgagccgtt
    14821 tcataccatg ttaaaattgg tgcattgtaa cgtttaaaat catcatccat accagcatat
    14881 atattgacag aggtagtacc aaattccaaa ctcaaagtag ccgctaaagg aactctcgct
    14941 tgacctacat ctatatattc ctgcaagaag gtcaattcct ctaacaaacg ttctttttcc
    15001 ttcttctgcg cttctacttt tgaagttcga gtcgactcag taaaggtctc ttccaaggct
    15061 ctatttttcg ctaactgttc ttctaactct tgcgaacgtt tagaaacatc caaggtggcc
    15121 aaggtgatat aggccttgtc cttaaaatta tctaacaatt ttttataata ggcttcattc
    15181 ctcaaatgaa tctcttttcg cttctcagtt tttttcatca actccgaaaa tgaatctaat
    15241 agttccagtc caccatattg aatctcaagc cctttgtttc gtgctgttcg aatagcctgt
    15301 tttgttgact tggaaagttt atcttcttca aaattttcct tgtatatttt cgcctgaata
    15361 cgaggttgaa tggtgtctcc catttcctcc gtttttcctg accaccttac tcccatttgt
    15421 tgcaaactat caataatagc cagattttca ggaaattctg tcttttcctg attgattaaa
    15481 ctttgagata ggcaaatact tgggtcaaaa gtcacaaaaa ccgctctctt actgcgagca
    15541 taggacttaa tagactgaat ggcaaaattc aagagttctt tatccccata atccaatata
    15601 ggtcctcttg ggatgtaaaa cattttatag cctagcggaa gagttctaat caaaatacta
    15661 gctgtcgcca gtaatttttc ttccctgtaa acaccaaact tctcatgttg ccaattagac
    15721 ttaacttcct cccaagcact actttgtaat acattggcta attcatgttc tttgacaaac
    15781 tgatcatatt ctaatgtggg aatgccaatt tgataacggt acatttccta ctctctttcc
    15841 tccagtattt tattactatt ctactacttt cgtttgaaaa gtctagtgaa aacatatttt
    15901 attttagttc tactccccct atgctgaagt tcaaactaag tcagtctctc ttctaatttg
    15961 aaatcaattg gtagggttgt taaaaaaact tccaattgtt tttcccagta gtaccactcg
    16021 tgagttccag cgctatggct ataggtcaca tcaaaaccta gttttttgag atttttcact
    16081 gcgagattat tggcttcgta caagaaatcc tgttcgccac accacgccca aagtttggtc
    16141 tttttatccg attttttagc cagactttca agagaatagg gactagttgt ccagtctcta
    16201 atctctccaa aaacacctct ccagtaggct ggacttccca gattttgact ttcaggagaa
    16261 aagttttgaa agctgagggc acctgaaaaa ctagctgcat gagaaaaacg atttgtcgca
    16321 agagccagtt tgaagcagcc gtaacctccc atagaaagac cagcgataaa ggtcttttca
    16381 cgcttgctag tcatattagg gaagaagcgt ttcagaacct gtggcaattc ctctgctaga
    16441 gccgtgtagt agtcaaaacc atactgggta tcggtgtacc aaccattgct ggtattgggc
    16501 ataacaacga tgagattagt tcctcgaagc aagcgttcta cattggtccg cttaagccaa
    16561 ctattatgat ttccagacat cccgtgcaaa aggtacaaga cgggaatatc ttcacactct
    16621 ggttcttcca ctcgattggc atcagggtag aggacattca ccccccactc catatccaat
    16681 acttgtgagt aatactcgat tttcattact gccatgattt tctccttcta tttttctata
    16741 agaaaaagcc gaaactcgac tttctctctg tttatttcaa cgattatttt gcttccatga
    16801 ctactggtaa aatagctgga cgacgcttgg tttggtcaaa gagatacttg gtcaaattat
    16861 ctcgaacctt ccctttaaga tctgcccagt caaagtcatc tccttgaaga taatcttcta
    16921 ccgtttggtt aatcaattct gaactttcac ggagaatatc gcgactcttc ttgagataaa
    16981 caaatccgcg cgtatgaaca cgagccctag ccacaatttt cttctcacga cggttgactg
    17041 taatagccac gatgaaaatt ccatcctctg acaagatctt acggtcacga agaacaacat
    17101 ttccaacatc accaatggca ttcccatcaa tcaagatatc tcctgctgaa accgatccag
    17161 ctggaacaaa gtctccattc tcgtaagcca tggtcgtccc ctttttagga atgaagatgt
    17221 gttctggcaa catcccaact gccatggcag ccttagcgtg agcatccaac tcacgatact
    17281 ccccttggac agggaagagg tacttaggtt gcaaaagatt gatcatcagc tgcaaatcac
    17341 gcacatttcc gtgccctgat acatgtaaac tttgggtaat caatttgaca accccacctg
    17401 cctgataaat catattttcc acacgcgcaa caaaggcttc tttagcaata gacggagccg
    17461 tagcaatata gaccaggtcc ccatccttga tttctacata acgatggcga ccaatcgaca
    17521 tcttacgaag tccattgata ggttcaccca tacgacctgt ctcaagaata atcaactcat
    17581 ggtcttcaaa gcgagacata tctttaggct taatcaagag aatttcgttg gctaaagaca
    17641 acttcttaag acgaatcgct gtgcggacga tattttcaat atcaaatcct gtcaagacga
    17701 tacgtcgacc tgttttatcc gcagcgtcaa aaatctgctg aatacgagaa agattactgg
    17761 aaacagctgc aacgatgata cgaccttccc agtcagcaat agtttgggta atttcatccc
    17821 taacttcact ttcactagcc acctgaatat tgctgtctgc attggccgaa tcactgagga
    17881 gagccaggac gccgtcacga ccaatctctg ccaaacgagc aaaatcagtt gcataagatt
    17941 cactagccgt ttggtcaaat ttgaagtcac ctgtataaac gatgcttcct tccgatgtct
    18001 tcaagacaat tcccagactc tctggaacgg agtaagtcgt agggaagaag gaaaccactg
    18061 tcccaccaaa atcaatctcc gtattctcat caatgacatg gaaatcatta aatttcttaa
    18121 cggcatcatt tcctttgaca aagagctttg ccaactcaat ggtcaactca gacccaaata
    18181 caggaacttt agcctctgcc aagagataag gtagagcacc aatggcatcc gcatgcccgt
    18241 gggtcaagaa aaccccagca atacggtcgc tattttcaaa aaggtaatcc atgtttggaa
    18301 tcaccacatc gacccctaat tgttcatttt caggatattt taaccctaca ttcaaaacaa
    18361 aaatggactc tccaatttca gcaatgtaca tattttttcc attctcacgc acaccaccaa
    18421 gtgttgttaa actgatatta ctcatttttc ctccaaaatc ttagtttatc ttgattatag
    18481 ggcaattcta ccctcttatt ctaaaagttc tgatactttc agccgaatct tttcctacca
    18541 ttataccatt tttttgatga ttttcaaaat gaaggtctgt tttcaaaaaa gagttgattt
    18601 cccaactctt tcctaacttc tactcttttt ccatcaaaaa atcataaatt tcttgcaccg
    18661 tacccagcgc catcatttct tggtctttaa cggtttgttt gagattttgg taaatttgac
    18721 tttctcctat ctcccgcttt ggcgcctctt tattgactgt catcacacca tcttttatcg
    18781 tcacaaagcc tagttcttca aatacttgaa tcatcttgac cagcaagatt tgttgaatat
    18841 taagatatgc agccaaatct ttcagcttgt agcgaatatc aaactctggg aactggtaaa
    18901 tagtcttgta caatttagca aactgatctc tagtcccata acctgtcaga taataggtct
    18961 tgtcaatatc atttttgaaa tagacagcag agaaatgctg ttcctgaaaa atggtcttca
    19021 gctgagtaat atcctctgga atgtttttta cgacaacagc ttcactagcc gcaagatttg
    19081 gcagttctcc aggaaaatcc aagactggaa caccttctgg caagactgca ttttttccac
    19141 gaatgttaaa aagttgaaca ccttccactc gcgcatccac catcatcaac tggagggcag
    19201 tttggccatt ccattggttg acagacaatt taaccgctaa ctctagattc ttggtttgag
    19261 aaaactctgt cgcccatctg ccttgaccaa aggctaccac ttcaaaactc gcctcaccct
    19321 tggaaatttt cagctttaga tgggcattac ctgcccccat agtacgagca ctttcgacct
    19381 gaaaattctt gatataaaaa ataggtttct gattatccat tccaaaagga gctaaacgtt
    19441 caaaactttt gaccgtttcc aagctaagtg cctccaaatc caactcttca tctaggttta
    19501 acttattctt gccaccagca tctgcacctt tttcacgaac ataatcttcc aaaacctgag
    19561 ataaatctga gagttgctca acttccagcg tcatacccgc tgcacctgca tgacctccaa
    19621 aggcgatgaa gaggtctcga tggggatcca gagcttcaaa aatatcgacc gcttccacac
    19681 tacgagcact gcccttggca cgaccgtctt ctatattaag aacaatgact gtctgtccca
    19741 attcttccaa taaacgacca gccacgattc ctagaacccc aggattccag ccttccttgg
    19801 ccaagacctg aaccttcttc tcaggatcca ccatggtctt ggcttcttca tagatagact
    19861 gaacgatttc cttgcgctct tcgtttttct ggtgaatcat aagggcaatc tcatgcgctt
    19921 cctcatcatc aaatccagtc aacaaatcaa tggcaggatt gggatcatcc aagcggccca
    19981 aggcattcaa acgaggagca atctggaaac caaccgtttc ttctgttact tcgttggcag
    20041 caatcccagc catgtccagc atttcttgca gaccaatgcg ctgggtatga cccaacattt
    20101 ccagaccata ttgaactaag atacgatttt catccgtcag actcaccata tctgcaatag
    20161 ttccaatagc gaccaaatca agcaattcca cttgcacttc ttctaacagg gcacaagcca
    20221 acttgaaagc aactccacaa ccagccaaat atttaaaagg ataatccgca tctggatgtt
    20281 caggatggac aatagcataa gcatctggca gggtttcagg catggaatga tggtctgtca
    20341 caatgacatc tactcccata gactgagcca atgcaatagc ctcatgacca gcaaccccat
    20401 tgtccaccgt cacaatcaag gaaattcctt cttgctcgat aaagtattta taaacactag
    20461 cattagggcc atagccatcg gtaaaacgat ttggcaggta aactcggcac tcagcaccaa
    20521 gttgttccaa actttccttc acaatagaag ccgaagtcat gccatccgca tcatagtctc
    20581 cataaacgag aatattttcc ccttcttcaa tagcctgacg aatccgctcc actgccttgt
    20641 ccatatcatg gagcagataa gcatcatgta agtcctccaa ggaaggttct aaaaacttct
    20701 tcagactttc ttggtcctga atccctctct caaacaataa ccgagccacc tcaggaccca
    20761 gtccagcctt cttggctatc tttgtaaaat ccgcatcttc tacctgcagg gcaaactgcc
    20821 attcataagt aggtgttatc aaaaagacat ccactctttc taagaattct attgcttcat
    20881 tataacatga tttagacgtt ttctctatcc agattgcttt tttataacat tttatagtat
    20941 attgaaacta gaatagtaca cctctacttc taaaatattg ttagaaatcg atttgactgt
    21001 cccgatcgat ttgtcctgtt cttatttcac tatagtgaat tttttcagat atggtttgac
    21061 aagaacattc tttcattgta gaatcgtgtt ataaaatata acacaaagga gatctctcat
    21121 ggctttagta gaatttaaaa acgtcgaaaa atattacgga gactaccacg cactccgcaa
    21181 catcaatctc cgttttgaaa aaggacaagt tgttgtcctg cttggacctt ctggctctgg
    21241 gaagtccact cttatccgta cgatcaatgg tttagaggct gttgacaaag gaagtctcct
    21301 agtcaatggg caccaagttg ctggtgccag ccagaaagat ttggtacctc ttcgcaagga
    21361 agtcggcatg gtttttcaac attttaacct ttatccacac aaaacggtgt tagaaaacgt
    21421 gacacttgcg cccattaaag ttctaggaat tgataaaaaa gaagctgaaa aaaccgccca
    21481 aaaatatctg gaatttgtaa atatgtgaga caagaaagat tcctatcccg ccatgctatc
    21541 tggtggacaa aaacagcgga tcgccatcgc tcgtggtctt gctatgcatc cggaactcct
    21601 cctctttgat gaaccaacat ctgctcttga tcctgagact atcggagatg ttctagcagt
    21661 tatgcagaaa ctggcgcatg atgggatgaa catgatcatc gttacccacg aaatgggctt
    21721 tgctcgagag gttgcggacc gcattatctt tatggccgac ggagaagttt tagtagatac
    21781 gacagatgtc gataactttt ttgacaatcc aagcgaacct cgtgcccaac aattcctcag
    21841 caaaattatc aaccacgaaa gtgacaaagt caaataagga ggcgcctatg aaaaaaaatt
    21901 ctttttatca gcattattga ttagcctttt cggccttgct gctgccaaac cagtccaggc
    21961 tgatactagt atcgcagaca ttcaaaaaag aggcgaactg gttgtcggtg tcaaacaaga
    22021 cgttcccaat tttggttaca aagatcccaa gaccggtact tattctggta tcgaaaccga
    22081 cttggccaag atggtagctg atgaactcaa ggtcaagatt cgctatgtgc cggttacagc
    22141 acaaacccgc ggcccccttc tagacaatga acaggtcgat atggatatcg cgacctttac
    22201 catcacggac gaacgcaaaa aactctacaa ctttaccagt ccctactaca cagacgcttc
    22261 tggatttttg gtcaataaat ctgccaaaat caaaaagatt gaggacctaa acggcaaaac
    22321 catcggagtc gcccaaggtt ctatcaccca acgcctaatt actgaactgg gtaaaaagaa
    22381 aggtctgaag tttaaattcg tcgaacttgg ttcctaccca gaattgatta cttcccttca
    22441 cgctcatcgt atcgatgcct tttccgttga ccgctctatt ctgtctggct acactagtaa
    22501 acgcacagaa ctactagatg atagtttcaa gccatctgac tacggtattg ttaccaagaa
    22561 atcaaataca gagctcaacg actatcttga taacttggtt actaaatgga gcaaggatgg
    22621 tagtttgcag aaactttatg accgttacaa gctcaaacca tctagccata ctgcagatta
    22681 aggaggacac cccatgatag atttatcatc ttggacagcc tattttcagg attttggaca
    22741 atttttcaat ggtttcctct ttactcttgc cctagcgatt ggatccttta tcctcgccat
    22801 ggtcttagga atcttctttg gtgccatgtc aaccagtaaa cgtccaattt tacgcatttt
    22861 agctcacatc tttgtggaat tttaccaaaa cactcccctc ttggtgcagt ttgttattgt
    22921 tttttatggc ctacctctta tcagtgacca tactatcatg attccaattt attggacagc
    22981 tgttctctgc atgggactct atcacggcgc ttatatcgct gaggttattc gttcagggat
    23041 tcagtctatt cctagtggtc agatggaggc cgccttgtcg caaggtttta cctatatcag
    23101 tgccatgcgc ttgattatct tgcctcagac cttccgcatc attctccctc cattgaccaa
    23161 ccaaattgtt aacctcatca agaacacctc tactgtagct atcatctctg gagtagactt
    23221 gatgtttgtg actaagtctt ggtcggctct caacggaaac tatatcccag cctttttagg
    23281 tgctgctctt ctctactttg ctctatgctt ccctgttgcc cagtttggtc gcaagatgga
    23341 gcaagccaac aaaaaagcct attcacttta ggaggttact atggaatcta ttttagaagt
    23401 tttaacccca gataacctag tctttatctt taaaggattt ggcttgaccc tctatatttc
    23461 tctgattgcc atcatcctct ctactatcat cggtacggtg ctagctgtca tgagaaatgg
    23521 caaaaatcct gtcttacgca ttatttccag tatttatatc gagtttgtgc gcaacgttcc
    23581 caaccttctc tggattttta ctatcttttt ggtgttcaaa atgaaatcca caccagcagg
    23641 tattacagcc tttactctct ttacatcagc agccttggct gagattattc gaggcggtct
    23701 caataccgta gacaagggac agtacgaagc aggaatgtca caaggcttca cctcagccca
    23761 aatcctctac tacatcattc tcccacaagc catccgcaaa atgctaccag ccatcatttc
    23821 tcagtttgtt accgtgatta aggataccag tctcctctac tctgttatcg ccctacaaga
    23881 actctttgga gccagccaaa ttctcatggg ccgttatttc gaaccagagc aggtcttcag
    23941 tctttgcatc ctgattgccc tcatctactt cagctttaac ctagcaattt ctagcctgtc
    24001 tcatatgcta gccaaacgtt ggcaacaagc tgcagaataa tactcttcga aaatctcttc
    24061 aaaccacgtc agcttcacct tgccgtatat atgttactga cttcgtcagt tctatccaca
    24121 acctcaaaac ggtgttttga gcagcctgcg gctagcttcc tagtttgctc tttgattttc
    24181 attaagtata aacagccact ctccagttca attggagagt tttttgatga gagtagatat
    24241 ttatagacct caatttgaca ccatacattt tctatgataa aatgtaacaa attcatttac
    24301 aacaaatcga aatctaaatg aaatggaatt ttctatgaaa tcagtcaaag gactactctt
    24361 tatcatagct agttttatct tgactctttt gacttggatg aacacttctc cccaattcat
    24421 gattccagga ctagctttaa caagcctatc tctgactttt atcctagcca ctcgtctccc
    24481 actactagaa agctggtttc acggtttgga gaaggtctac accgtccaca aattcacagc
    24541 ctttctctcc atcatcctac taatctttca taactttagt atgggcggtt tgtggggctc
    24601 tcgcttagct gctcagtttg gtaatcttgc catctatatc tttgccagca tcatccttgt
    24661 cgcctattta ggcaaataca tccaatacga agcttggcga tggattcacc gcctggttta
    24721 cctagcctat attttaggac tctttcacat ctacatgata atgggcaatc gtctccttac
    24781 atttaatctt ctaagttttc ttgttggtag ctatgccctt ttaggcttac tagctggttt
    24841 ttatatcatt tttctatatc aaaagatttc cttcccctat ctaggaaaaa ttacccatct
    24901 caaacgctta aatcacgata ctagagaaat tcaaatccat cttagcagac ctttcaacta
    24961 tcaatcagga caatttgcct ttctaaagat tttccaagaa ggctttgaaa gtgctccgca
    25021 tcccttttct atctcaggag gtcatggtca aactctttac tttactgtta aaaattcagg
    25081 cgaccatacc aataatatct atgataatct tcaagccggc agcaaagtaa ccctagacag
    25141 agcttacgga cacatgatca tagaagaagg acgagaaaat caggtttgga ttgctggagg
    25201 tattgggatc acccccttca tctcttacat ccgtgaacat cctattttag ataaacaggt
    25261 tcacttctac tatagcttcc gtggagatga aaatgcagtc tacctagatt tactccgtaa
    25321 ctatgctcag aaaaatccta attttgaact ccatctaatc gacagtacga aagacggcta
    25381 tcttaatttt gaacaaaaag aagtgcccga acatgcaacc gtctatatgt gtggtcctat
    25441 ttctatgatg aaggcacttg ccaaacagat taagaaacaa aatccaaaaa cagagcttat
    25501 ttacgaagga ttcaagttca aataagtaat catactctcc tgggatttcc caggagagtt
    25561 ttttatagcc aaatgaaata aaaccggaac gatggaattt tggcattcaa atcaattgat
    25621 aagaatattt tatagtggag tgaaatagga tacgaacaaa ttgattagga aaatcaaatg
    25681 aatttataga aatcttttag cagttatgtt gtcctattct agtttcaaaa cgctatagaa
    25741 gcagcattgt gctagtctag attcagttta ctatactaaa acgagtagct tgaaatcaaa
    25801 aaacccaccc tcacaggcag gttttatctg tattattcag ctagattatg ctttaccttc
    25861 tgaaccgaat acgtcgatac gttcttcaac cgatgcttgg atagctttta caccgtcagc
    25921 caagaattta cgtgggtcga agagtttttt cttgtcgtat tctgcttcgt ttgcttcgta
    25981 gtcacgagca aatttacgag ttgcgttagc gaatgcgatt tggcattctg tgttaacgtt
    26041 aactttggca acaccaagtt tgatagctgc ttggatttgc tcatcaggaa tacctgatcc
    26101 accgtgcaat acgattggga atcctggaag agcttctgtc aatttttgca agtggtcaag
    26161 gtcaagacct tcccagttta ctgggtaagg gccgtggatg ttaccgatac cagctgccaa
    26221 gaagtcgata ccagtttcaa ccattgcttt agcgtcttcg attggagcca attcaccttt
    26281 accgatgatt ccgtcttctt caccaccgat agtaccaact tcagcttcta ctgagatacc
    26341 tttagcgtgt gctttttcaa caacttcttt agccaattta aggttttctt caactggaag
    26401 gtgtgaaccg tcaaacatga ttgaagtata accaacttcg atacactcaa gtgcatcttc
    26461 gtagtgaccg tggtcaaggt ggatagctac tggtacagtg atacccattg attcaacaag
    26521 gttagcgatc aagttgcgag caactttgta accacccatg tatttagcag cacccattga
    26581 agtttggatc aaaactggag cttttttagc ttctgctgcg cgcaagatag cttgagtcca
    26641 ctcaaggttg tttgtgttaa atccaccaac tgcataaccg ttgtcacggg ctgcttggac
    26701 aaatttttct gctgaaacga ttgccatttt atcaggcctc ctgtatattt ttatgggtca
    26761 tcccatttac attgttcatt ttatcacttt ttgccaaaaa aatctagttt ttcccgcagt
    26821 ttcgattgat tttcttctaa ctccatctat gtaaaccctt tctctcccta gtcttggacg
    26881 acttttggaa aatctataaa gaaggttaaa cgattctcct ccatctcgaa acgataagct
    26941 aatttttcat gttctaatag actcttaacc acaaagagcc ccataccaga ccccttgacc
    27001 ttgcgactgg cattgtcaga aaaagactgg gctagttttt cttgttcctc tgagctacag
    27061 ctattttcga taaaaagttc tccttctctt tctccaattc gaactaagcc acctggaaca
    27121 gagtgcttaa tggcattgct gatgagatta gaaagaatca acttcataac tgatgggttt
    27181 agataagcct gctgatgggt caaactattg tctatctgga gctctctttc cttggctagc
    27241 aaggcataat ctttgaccag attttgcgtc atctggagga ggtcaattgt ttccctatca
    27301 tctcgcaatt cctgcacaga agagagggaa agtatctgca gaacatggtg attgagttca
    27361 tccacaatcc ccaaggcaac tcccagatac tggtctctat ccttataacg accgatattc
    27421 tctctcatat tttcgattag gattttcaaa ctagccagcg gtgttttcaa ttcatgagaa
    27481 gctcctcgta ggaattcgac cttcatcttc tccagctgga gaatggcttc attcttttca
    27541 tgcaagtccg caataacagt caagagatgc tggtagaggc tattgatttg ttccttgaga
    27601 ttacctatct catccttaga atccacgcgc aatcgcactt gggaatccag gtccatcatc
    27661 cgacgggtca cccgcttgat ttccaagatc ggtgcaacaa tagtccgagc gtagatgtag
    27721 gccaccaaga gggaaatcag aaaggaggcc agcaaggtat agggaagaaa ctggagactg
    27781 atttgctccg cttccttttg taaatccatg gaagctagaa actggagaat catagtagca
    27841 ccgtcttgcg ttttcacctc gcgctcctca ataaagagag aggttgtctg gcggtctgtg
    27901 tccagaggaa gactgtcctt gacttctaac ttgtcctcgg tcatctcacc tttgacggtc
    27961 cccttgatat cactagtctg ggaatacaag tctaacactt gctcgatact ctgcctatct
    28021 ttcccttcta gggactgggc aatggctgtt gccttttgac caatggtttc ctgacgatga
    28081 ctcagataag tcgaaggaaa aagaaaataa atagctaaat gaaggcagat aaccagaaca
    28141 ctaaatatcg agaaggtata gataaatatc tttgcaaata aacctgttcg tttcattttc
    28201 gctccaattt ataaccaaca ttgcgcacag tgaggataca atccaagtct agctttttcc
    28261 gcaattcctt gatataaaca tcaataacac ggtcaaaggg aacctcatct gtcgctttcc
    28321 agacggcatc gataatctga gatcgagtca aggcccggcc ttcatttttc actagatagt
    28381 ccagaatttc caactctttg gcattgatag gcacttcttg acctgcgatg cttgcactgt
    28441 agctttcaaa gtccaccttg gtatccttgt aagaaaagat tcgtcctgta tcgtagtagc
    28501 gcttgaaaat cgcgtccacc ctcactttta aaagggagag ggagaaaggt ttttccagat
    28561 agccatctgc caaagaggca aaggcactca tcttgtattc ctcatcttga aaagctgtca
    28621 acatcaagac aggaacctga ctggttttac gaatctcagc taggacttct aagccgttga
    28681 gcttgggcat ctggatatcc agtaaaacca gggccacctc atagctagaa aattgctcca
    28741 gagcttcctg accgtccgct gcctcaatag tttcatagcc acaatccgtc aaataatcac
    28801 tgaccccctc acggatcatc tcttcatctt ctacaattaa aattttcata ctttaactgc
    28861 tctctatttt ttatttttct tagaataaat acctactcta ttttctatta tagtctcttg
    28921 ctggcctttt gtctgcaagc aactgaccac tagataaaac gttgtgaaat tcctttctca
    28981 taaattccat aactttagta tattatattt aagcactaaa gtacaaagaa agcaactgaa
    29041 agcaatgatt ttcaccactg ctttcggatt tattttgaat tgttaaatag ccattcctat
    29101 ccactattct tgaatagaaa cacaagatgc aatctttatt ctagactcat tttttcaaat
    29161 ttattcacca tccagcaaga gctcttttgg ttgttttcta aggagattgc ttgaagcaag
    29221 cgccataacg agaaccacta gaaccaaggc aaggacaaaa atgatgataa agtctgatgt
    29281 ctgaatggaa atgtctaggc tcgacaaggt cttgctaaag ccatctactt ctgcaccacc
    29341 accaaggtta gaggcttgag ccgccttact agcctgtttg gcaacacctg aagtcacatt
    29401 ggcaaggaca gtgtttccaa ttgcacgggc agtgtaatta gctaggaagt aagcagaaac
    29461 tagagcaggg atagcaatca agatagattc ggtgatgaat tgacccaaga tacttgcctg
    29521 cttgaggccg atagagagga gaattcccac ttccttgcga cgggcgttga tccaaaggct
    29581 gagcaagagg gcaaggagga gaactgagaa gctcaagcta ccccagaaga ggaggttggc
    29641 catcttgtac ataccagaga tagattgctc aagagctggg tagttagagg agctcttgac
    29701 gagtgtgtag ctcttccagt tgataccact gatgccattc aactctttca taacatcatc
    29761 caagttcttg tctgctgtta caaagaaggt tgcgtcccca taaatggctg tgtcttctgt
    29821 gtatccataa agttttgcag cagtgtgaat gtctgtaata gctgtgtttt cgtaaagttc
    29881 ttgtgagtag gttactgctg acttattatg accatcaaag agtcccttga ttgtcacttc
    29941 aactgtttcc ttggctcctt tttcattatc tgcatcgtag atattagagt ccagtttaac
    30001 cttgtcccct actttccagc cgtgtttggc tgccaagtcc ttgtgcaaga ggattttatc
    30061 cttgtcgtcg ttggttaagt gctctccttc gactagttta taagaaccag agacaaactt
    30121 gtcttcttta gaggagtcat tgacacctgt aatcatcaag ctacttccaa aacgcttggc
    30181 acgatcagca gtgagattct tcttggtttc tggcgtttca atcaggtcat atccagtcaa
    30241 atctccgata gcgttgatac gtttgacata agactcgatg gccttgtttt cggtgatttt
    30301 tttgatgtct tcacccttga tattcccagc accacgaggc gttccttggt tgacgcgacg
    30361 attgatttgc atggagaagc tattagtgat atttttaaag gtctcctgag aagccttggc
    30421 agtagctccc ttgattgaca agccgaccaa actcaagctc gccatgagga gaataatcag
    30481 gaagatgaca atcgatttga aaaacttcct tgtaacatag gcaaatgcgt tgtgtaacat
    30541 agattccctt tctagatttt gttttaatca ttctatcaaa ataagctcaa attatttact
    30601 agtattgcgc gtttcagtca gtttcttatc ctttaattca agtgtaatat ctgacgcttg
    30661 tgccacttct ttactgtgag ttacgacaat cacacattta cctgttttct gggcaagtga
    30721 tttgagtagt tcgacaatat ctccagcagt tttaggatcc agatttcctg ttggctcatc
    30781 agctagaata actggagctt ctgagaccaa actgcgagca atggcaacac gttgctgttg
    30841 accacctgat aactggagaa cattccgctt gatctggctt tcatccaaac caagctcaag
    30901 aagtgtatcc ttgcttgcct ttttgttgac caagcggata ttttccagcg gagaaagata
    30961 atctatcaag ttataatttt gaaagaccag ggaaatatgg tgcatgcgat ggtaagaata
    31021 gcccttctta cgaatatcct ctccttgaaa aaggatagaa ccttcaacag gactatctag
    31081 accagcaagt agggacaaga gtgtggattt tcctgctcct gactccccaa taatactgta
    31141 aaattttcca ggttcaaaat tataatcgat ctgatatagg actgcttcag cagtattctt
    31201 ataacggtag gtaacatctt gtaattgtaa taaagtcatg atttctcctt cttaactaat
    31261 agatgataaa atttctttcg gtgattttct aaataagaat aggaaacaaa gggctacaga
    31321 taagcaacta agcagaacta gaaaaacata ggattctgca aaagataaga tgctagttga
    31381 taaactgctt gctttggcta gtgtatcttg taagcttgcc tgatctccac ttgctagtag
    31441 agtttggagt agataacttg tgattccgtt tcctgcaaca aatgctggaa gcaaagctcc
    31501 aagagatacc aaaactacct ctaaacagaa ttgtaggaag atcgagctct tgccttttcc
    31561 aagtgcaagt aaaatcccca cttcatagac ccgttctctc aaccagagag acaaaaccag
    31621 aattaaggct ccagctcctg ctatcaacat cccataaagg aagatggtca agaaggtttg
    31681 gaaagttgca actgagtctt tgatttgttc aaaagccttg ttttcctttt cgacttggta
    31741 gccttgattt tccaaggcca agttttctac ctgcttcatg agtccgtcca tttccttagg
    31801 attttctaca tagaagcgtg ctgcactgac ttgagcttca ctattgccca aaagggtttg
    31861 gctactttca tagtctgtaa agacttgatt ttcactgaag tcagaagaca agcctgtgaa
    31921 tttctcttgt tttttaccag aaaagatgcc gataatctca aactctactg tttgtccttt
    31981 tccagattca gactgaccag catccaagcc aatcttgtca tgaagtgaaa gaccgttctt
    32041 cttagccaat tcttcgtgga taaggatttt cttggaatcc cctttttgaa ggtgtcgccc
    32101 ttcttttaga ttgaaagccg aactggtaaa ggttacatcc ttggatgaat cctcaagagc
    32161 cgttaagcta accaagttat tgtctgcagc tgataaatca tcacgctcca cgctctgctc
    32221 accagtcact gcttccttgt cttttagttt tgcgaccgtc tcaagttcag gagagacatt
    32281 ttccagcccc ttaatcttgc ttacagatgc taggtctgac aacttgaatg tctgaccatt
    32341 ctctatcttc ttaatagaaa aagatgtatt gagtgattta taaagattgc tttctactgt
    32401 tttgttggac ttcatcagag tcaaacaggc tgaaattccg gccaataaga ccaataaaat
    32461 cagaaataaa ataaaacttc tcagtcgctt tctgctgaca taagcccaag atctttggat
    32521 tggattcatt tgtcacctcc atatttgtaa gactattata aaacccaaat atgaaatgtt
    32581 tatgaaatac gaaaaaaaat atcgagtagg ggataatctc tagcccctct cacaccaccg
    32641 tacgtgccgt tcggcatacg gcggttcaac taacttttaa cgcatgtcgt tcaaggtaat
    32701 aatccaaaca cgaaacctgt tcacgttttt caaggactgg ttttgatata gcacgtttaa
    32761 gtaccgactt ctgagctact atagtagatt gaaactagaa tagtacatct cttcttctaa
    32821 aacattgtta gaaatcgatt tggctgccct gatcaattcg tcctactctt atttcatttt
    32881 actataattg atagtggtcg ccccagccag ataccttatc tgctatccat ttaggaac
//
LOCUS       DAVAZV010000019        31002 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVAZV010000019 DAVAZV010000000
VERSION     DAVAZV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31002
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.019"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(298..516)
                     /locus_tag="VQT46_000873"
     CDS             complement(298..516)
                     /locus_tag="VQT46_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2370924.1"
                     /translation="MVLNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(762..1040)
                     /locus_tag="VQT46_000874"
     CDS             complement(762..1040)
                     /locus_tag="VQT46_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370925.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEMLELACWFRVIIVIEANSYV
                     NIRSSRLLPKFKTQKINSWCAAYSIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQT46_000875"
     CDS             complement(1254..2885)
                     /gene="rlmD"
                     /locus_tag="VQT46_000875"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2370926.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSLHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWCTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSQKNASLNKITNAHYVCDTAENAMKKWLKEGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2959..3933)
                     /locus_tag="VQT46_000876"
     CDS             complement(2959..3933)
                     /locus_tag="VQT46_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET2370927.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDVRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQT46_000877"
     CDS             complement(4007..4621)
                     /gene="pmp23"
                     /locus_tag="VQT46_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET2370928.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(4621..5595)
                     /locus_tag="VQT46_000878"
     CDS             complement(4621..5595)
                     /locus_tag="VQT46_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET2370929.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQKENGTYSILIKNIEDIQSK"
     gene            complement(5603..6859)
                     /locus_tag="VQT46_000879"
     CDS             complement(5603..6859)
                     /locus_tag="VQT46_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET2370930.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLASGGHLTHGAPVSFSGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6921..7352)
                     /locus_tag="VQT46_000880"
     CDS             complement(6921..7352)
                     /locus_tag="VQT46_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370931.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(7354..7956)
                     /locus_tag="VQT46_000881"
     CDS             complement(7354..7956)
                     /locus_tag="VQT46_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET2370932.1"
                     /translation="MMDRIRQELENGGAVVLPTETVYGLFAKALDEKAVDHVYQLKRR
                     PRDKALNLNIASFEDILHFSKNQPTYLQKLVETFLPGPLTIILEANDRVPYWVNSDLA
                     TIGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFL
                     TGQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQT46_000882"
     CDS             complement(7940..8779)
                     /gene="prmC"
                     /locus_tag="VQT46_000882"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET2370933.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTLKDQFGQNRMVVVDD
                     GQD"
     gene            complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQT46_000883"
     CDS             complement(8779..9858)
                     /gene="prfA"
                     /locus_tag="VQT46_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET2370934.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9855..10445)
                     /locus_tag="VQT46_000884"
     CDS             complement(9855..10445)
                     /locus_tag="VQT46_000884"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET2370935.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRGLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPEINKENEEK"
     gene            10568..10750
                     /locus_tag="VQT46_000885"
     CDS             10568..10750
                     /locus_tag="VQT46_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET2370936.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10887..12260
                     /gene="mnmE"
                     /locus_tag="VQT46_000886"
     CDS             10887..12260
                     /gene="mnmE"
                     /locus_tag="VQT46_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET2370937.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNIRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTKLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEANLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLIEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQT46_000887"
     CDS             complement(12307..13242)
                     /gene="dapA"
                     /locus_tag="VQT46_000887"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET2370938.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(13298..14374)
                     /locus_tag="VQT46_000888"
     CDS             complement(13298..14374)
                     /locus_tag="VQT46_000888"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET2370939.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPCDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14716..14788)
                     /locus_tag="VQT46_000889"
     tRNA            complement(14716..14788)
                     /locus_tag="VQT46_000889"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14753..14755),aa:Thr,seq:ggt)
     gene            complement(14888..15397)
                     /locus_tag="VQT46_000890"
     CDS             complement(14888..15397)
                     /locus_tag="VQT46_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET2370940.1"
                     /translation="MKKLTIRDIADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15395..15491)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15520..15951
                     /locus_tag="VQT46_000891"
     CDS             15520..15951
                     /locus_tag="VQT46_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET2370941.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            16033..16410
                     /gene="mscL"
                     /locus_tag="VQT46_000892"
     CDS             16033..16410
                     /gene="mscL"
                     /locus_tag="VQT46_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET2370942.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQT46_000893"
     CDS             complement(16452..17546)
                     /gene="hemH"
                     /locus_tag="VQT46_000893"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HET2370943.1"
                     /translation="MKKAILMMTFGSPEEISFEGVAEFFTNIRRGVRPQDHEIQTLYD
                     NYIRIGGTPLQRITREEVNLVKERLGEEYGIYFANKFSRPFIPDVIKQMETDGVEECI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEVLLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTVRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQT46_000894"
                     /pseudo
     CDS             complement(17624..18456)
                     /gene="srtG2"
                     /locus_tag="VQT46_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218039.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG2"
     gene            complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQT46_000895"
     CDS             complement(18534..19532)
                     /gene="srtG1"
                     /locus_tag="VQT46_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000851047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system class B sortase SrtG1"
                     /protein_id="HET2370944.1"
                     /translation="MKTKREKPKKSLSRRLVLAVDGVINHLLLIFAALIFLFGFYALW
                     DSNQVYSLASSSEYEAYRPVTTQQDELASFSGFSKLQELNPEVLGWINVYGTNIDYPL
                     VQAKDNEKYLNKDSKGEFAATGAIFLDARNNPKFEDFNTIIYGHHVENGVMFGDVAKF
                     ADQEFFDQHRYGSIYYNGVEKGLEIFEMLEVDAYDFNIYDPGIQGEDRQQAYLDHLLS
                     VAMHKRDISLSPSDRIILLSTCFLDVTNGRHIVVAKITDTVPKNTFHTKKSKPFPYSV
                     FDDSSLGRFLSSIPLWIWYLILFVLFLLLIFLLLVLYLILRRRRESKKNARSRPFY"
     gene            complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQT46_000896"
     CDS             complement(19550..20746)
                     /gene="pitB"
                     /locus_tag="VQT46_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus major pilin PitB"
                     /protein_id="HET2370945.1"
                     /translation="MKKTFFKKLFTASIAAITALSVFRGVPTFADDNSAITKANGENN
                     AVVKINKTLNIAEGITTPTATFTFKFTEKTGQSSNGAPYQTGVAIPDRNVEYNKNDHP
                     TADKIQKATEDIFSGVAYGHAGEYVYDVAEAKTGWQAITKNGKTIDAMRYDKRTYEMH
                     VIVKNKVNGGVYISSVYFKENNKSNAPKVEPSEQGVYNLFDNTYTKDASKEPNPDDPS
                     QVDPNAKALTITKKVDGASGDKTRDFQFHIKIQLPSTNKTAETPVTNIIVKHGSKSEV
                     LAVVTPADTVEYNFTLKDGETFTVEQLPAGSKYTVTETGVAGYTDSSIYTTNGAEQTS
                     QGQKNVDFTLTDILIGEKKNDNKVTNKIDDVTPTGLLIDNLPFILMIGLGLAGFVVLS
                     KKRREA"
     gene            complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQT46_000897"
     CDS             complement(20791..21342)
                     /gene="sipA"
                     /locus_tag="VQT46_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PI-2 pilus system signal peptidase SipA"
                     /protein_id="HET2370946.1"
                     /translation="MLLKKKHKKPVTQVNRDKSPPSVWGDILYLVSKLLMVGFVLAIL
                     YFFVFGLLRYNDDGMKPALKDGDLVVYYRLDKRYSIGDLLVYSYKGKERVARVIATEG
                     STIDINENGLIINGSPQQEQDIYKETLLYKEGATFPMKVPAGQLFVLGDNRTTAVDSR
                     AFGTIPIQDTQGKVVTVIRRRGF"
     gene            complement(21342..23297)
                     /locus_tag="VQT46_000898"
     CDS             complement(21342..23297)
                     /locus_tag="VQT46_000898"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HET2370947.1"
                     /translation="MDAGIGTGTNINAGLTEAQRLLQSARAGAKKVVILLSDGEANMY
                     YESNSGRTIYNYYSNPNVGRMIDTPYWFTSGLERGMLNISSLIAPKIDGFYSIKFRYY
                     IGSNDSITSLKGYISGYNSGIPNEIFSANNENDLQQKFKEITDKILPLGVHHVTISDV
                     LSKYVQLLPGDASHLRVVKIKDGNEQELNDNQVTIETKKNEQGLVEVTAKFNPSYTLE
                     DDAKYVLKFTVTSSQEAFDAIAGDKTLTSDDAEEADATKLYSNKGAKVAYSYGIGTSR
                     TKIKDYSEKPTFKPSDPLTVPVEIEWKGVDGKSNPSANRPPSVELNLNQKKDGSIKDS
                     YRKVTSPVQTNSFTENTSFAKVAKGYDYELKAPDAPGYTVEVQKTGTKEKPSFKVIYR
                     QLPSLTVKKILEGEQSPNKSFTINVTFSDKDGKPINGKFGNTTVTNGKAQISLKNSQE
                     TALSYLPRDTHYKVEEVENSRTGYHVTYEKQEGTLSEDVQTIVTNHRLPTLSVTKKVT
                     GAFANLLQSFKITINVKDAQNKPLNGSYSAIVNNQKTTLQFTNGKATVDLKKDKTIKI
                     LDLPLNARYSIEEEASSSRGYQVSYDKKEGTLDANKSATVTNNKNSVPETGIDFLSST
                     LVLGVVLPLGGIFFIILLGHLVVNRRK"
     gene            complement(23427..23930)
                     /locus_tag="VQT46_000899"
     CDS             complement(23427..23930)
                     /locus_tag="VQT46_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HET2370948.1"
                     /translation="MNVQYDFKKIQYFTSSLVIFLAILFLCAPINSLRADSITEPQTT
                     LHKTITPISGQKDQYELSLDITSKLGTETQSEPLDVVLVADLSGSMEERDVWSYSSRR
                     YISRIEALKHTLKGVNGRQGLIDTILSNSQNRLSIVGFAGKIDNQYNDRYYNEYYLSY
                     QYGTWPN"
     gene            24289..25512
                     /gene="pepT"
                     /locus_tag="VQT46_000900"
     CDS             24289..25512
                     /gene="pepT"
                     /locus_tag="VQT46_000900"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET2370949.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPRQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEV
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSDRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(25548..26177)
                     /locus_tag="VQT46_000901"
     CDS             complement(25548..26177)
                     /locus_tag="VQT46_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370950.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSANSKDKTALLESTKAILVLNHQIQSKVSASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            26142..26363
                     /locus_tag="VQT46_000902"
     CDS             26142..26363
                     /locus_tag="VQT46_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370951.1"
                     /translation="MDLFQELICLVQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(26634..26982)
                     /locus_tag="VQT46_000903"
                     /pseudo
     CDS             complement(26634..26982)
                     /locus_tag="VQT46_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27087..27647)
                     /locus_tag="VQT46_000904"
                     /pseudo
     CDS             complement(27087..27647)
                     /locus_tag="VQT46_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQT46_000905"
     CDS             complement(27873..30992)
                     /gene="phtE"
                     /locus_tag="VQT46_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET2370952.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQISQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKELSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPSN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLSETGNSTS
                     NSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSENGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         8835 a         6360 c         5686 g        10121 t
ORIGIN      
        1 aaaaggatct agtttttatt tttagttaaa ttatgtctat atttttcatt aactcatcaa
       61 taaaaatttg tttgctaata tctctttctt ctgattttgt ttcaaggatt attgctacat
      121 cattcatatt tttaggtaaa taccaaccat ctggcttatc tgaatatccc ttgaagccta
      181 attgattaaa agtagttatt tgaccagtac cttgattgat gttttcttca acttcattaa
      241 agcctatact tctcttgcat aatccctaac ttgatcttct gtccttaaag tcattttcta
      301 ttcctcgtca ctaaaattat cttcaaaact aataatatca ttaggagtgc aagataaagc
      361 cttacatatt ctttctaaat tcttaaatgt aattggttta tcctttccca tttgtgccat
      421 aacatttgtt gtaagtcctg ccatagctat tacatctgtt ttctttagtc ctttttttgc
      481 taactgtatc cataatggtt tatagttaag taccataata tccctctttt tttcttcatt
      541 aaatttattt aattatagca taaatattga tttcattcaa tcttacattg atttagtgat
      601 ttgttttaga gaatttgttg tgttattccg tccttatttt gccataaatt gttttaagtg
      661 ggacctctta tccttaccat ttttacctcc taattttgag tataaaaaag acgatagagt
      721 ttttaatttc tatcgtctga gatttacata ttaaattttc atcacaaaat aagactcttt
      781 aaagaatctt taaattcatt ggtatgctgc ttacaatatc cattattaaa atggatacta
      841 taagcagcac accaactatt tattttttga gttttaaact ttggtagaag tcttgaactc
      901 cttatattta cataactatt tgcctctata actattatga cacgaaacca acaagcaagt
      961 tcaagcatct ccatatcttt attcaaatga ggactaagat attcacaaac tttatcataa
     1021 acctctttat cttttttcat aaaaggggca tacaacttag caaatttatc ctaaaatttt
     1081 ttgttgcctt tatcaatcat ttcaacgctc ctttaaatat aaaaataatc ctatcaatct
     1141 ttatattgag cctattttct aattgatacc ttgcaagaaa ggaataatag ctgttcctat
     1201 accaagtagg aatgtaataa atgcagaaag tcatatactg tcattctttt ctattaaatc
     1261 attttgaagt gtctcaaagc atccatgatg gcttcttctt tttcaggtgt acactgtgga
     1321 ataatttgtt tatccttttt agacttgttg taatgttctc gtaattctat tccacatttc
     1381 ttttttatct gtgcaatata taatgtcgaa acttttaatt caaatttatt ccaaacatat
     1441 tctttgattt gagcatatgt tgctttgctc tccgcacttg tcaaatccat ctcatccagc
     1501 tcaatttcaa cacttatgtg cttatcgaca tcgagtttgg acaaaagtgc taccgtctcg
     1561 acgtgatgcg tttgaggaaa tagatccacc ggctggactt tcttcaattc atatcccaat
     1621 tcttggtaga gtttgatatc acgcgccatg gttgcgacat tgcaggagat ataggcgatg
     1681 cgatcggctc ctgtttgggc gcttgctttg ataaagcttt ctgtcaagcc cttgcgtgga
     1741 ggatcaacca agataacggt tggttgaata ccttccttga gccatttctt catggcattt
     1801 tcagccgtgt cacagacata gtgggcatta gtaatcttgt tcaaagaagc attcttctgg
     1861 ctattctcaa ccgcttctgg aatcagttca acaccgtaga cttctttgac atgcttggcg
     1921 actgataaac caatggttcc aataccagaa taagcatcaa taaccacgtc atcttttttt
     1981 aactctgcaa agtcaatggc tgtttgatag agtttctccg ccatttcagt attgacttgg
     2041 taaaaggctg ggccagcgat ttggaagtca tttcccaaca tctggtccgt aatatagtct
     2101 tgaccataaa gagtgcacca ctccttacca aaaatcgcat tggtattctg gtcgttgata
     2161 ttttgcatga cagacacaat ctctgggaac tgcttgataa cttgttcaat caattggtca
     2221 acacgaaaaa cttttggacg agttgtcacc aaaacgacca tgatttgtcc tgaatagtga
     2281 ccacgacgca ccacaagatt ccgaatcaat ccagactgtt ccttttcgtc ataaggtttt
     2341 aaatcaaaac gacggagcag gtctcgaaga gctactacga cttggtcaat gacaggatcc
     2401 tggataaaga aatcttcaag gggcatgagg ttgtgcgaat tcttacggaa aaatcctgtt
     2461 tccaagacac cattcactcg acgaacgggc acctgcgcct tattgcgata cttgactgga
     2521 tgttccatac caagcgtttc agcaacttct acatctgcaa ttccagcaat cttgtagaga
     2581 ctgtccttga cttgcttggt tttaaacttg agctgttctg gataagaaag gtgtcctaaa
     2641 tccgcgattc ctgaacgcag gtaagccaaa tctagatctt gattacggtg tagtgactgg
     2701 acaaggtatt tttcaacttt tccaaagcca atctttttat tgaccttgag gacacgcatg
     2761 agaatttttt cactcggtaa agcattctct acaaaaaaga ccaaaccatc taccttggca
     2821 actcctgccc cttcatgggt caaatcaaca atttcaactt ctacaatatc atttttcttt
     2881 aacattcttt tctctttcta ttggccgaca aaaaagacgg caacgttacg attaccatcc
     2941 attataccat gaaatttctt aagaaccaaa actcttgaag aagttgacaa gggcttgcca
     3001 gagggagctt aagaagttac caccgtcctc tagcgcctta tccgcatcaa agttaaggtt
     3061 gatattttta aaactgtcgc cagcttgtga tacgatgctt tgtttaaggt catttagggt
     3121 tttagtgaaa tctgcattgc tgaggatatc actctttgag agattcaagg caaaattgat
     3181 gatgatattg atctggtttc ctgttatgac ctgatcaagt ttgtaatttt ttaaggtatc
     3241 ttcaacaatc ttgcggacat cttcttctgt cagatttccc ttgctttctt tagctttggc
     3301 gagtcctgac ttgatatcag ctagggcaac gtttaattta ttagcatcat agcctgattt
     3361 gtccttgttt tcagcattga tatctgacaa agcctttagc tcttcttgag ccaaatcttt
     3421 attggcttgc ggcaccttgg ctccattagc ttctagcgaa tagtagatcc cagccaaagc
     3481 actctcacct gtaactggaa taggggctgc tacagtgatt ttggcatgtt ccatacccag
     3541 cgttactgct gcgtttcggt acatatcctg agtcacctta gtgatatttt ctggtgtttc
     3601 aatcttgacc tcaagtggcg atttgtcacc tagcttttga atcttggctg atgaatacaa
     3661 ctgtaagcta gagtcattgg ccacattcat gattttagaa taaacatcag gtgtcatggt
     3721 cttgagttct ttggtatctg ttgaggcatt gtagcccagt tttttaagag tttgattttt
     3781 ttggtcttca gatagggagg aacctaggac atattcaggt tggacatagg tttcatcgat
     3841 aaccttttga acatctgttg ctgcatggac gctattcata gctgttactg cccacaagac
     3901 cgcagcactg gtcagaaaga gtttctttct catagggaat ttcctccttt acttttctag
     3961 agtaatatat ctatcttaaa gaaaacttat aacaaaaaca cctggtctag ccagatgttg
     4021 aaaagagagt gaaacatttg atgatgtaaa ggttaagtcg tacctgtcta gaataataat
     4081 agtttcctcc atttacatag agttcagcac cgtgaaaaat ggaaatgggg tgaatataac
     4141 tataagtctt tccagtcgta ttaccaagca agggggcaac agtctcacga gagtactgtt
     4201 tggctagagc caaggtattt tccttgccat tttgggcgat aaaatcgata taggcaggtc
     4261 caaaattata ggcttgaaca gctgtccaga tatctacccc cttcttctgc gccagataga
     4321 gattgcctgt cagagtttga atgccttgcc gaatgctaga ggcattatca ttgatggtgt
     4381 tggttgaacc acttgcagac tcactagact gcataacatc gccttctttt ccttttgttt
     4441 cagtataaat catagcaagc acaagctctt cgtttgctgg ggtgtctttt tcactcaaga
     4501 tttctcgcac catgggttga taggtcatga cttgtttgac atcttgatga acgcggtaag
     4561 ctttatagcc agcaaaaagg aagactgcta gtacaagcac tcttcgaatt cgtttaaaca
     4621 ttatttactt tggatatcct cgatattttt gattaagata gagtaggttc cattttcctt
     4681 ttggataaac tcaacagact cggcgtcttg atagacgtta ttgggaacga tgagctcaat
     4741 tccatttgat aaggagagtt tttggttttc aaatttcttt aattggcgac tggcatcaat
     4801 ttcatcaaat tgaacaggtt ctggtacggc ttctttgact tggtcaataa agctcaaacg
     4861 agccgtcaga ttgttgtcaa aaaggtcatt agccaatttc tcaggtgaca attcattgct
     4921 ttcttctagg ttgttgaaaa tcgctgattt gaccttggat tgaaattgaa aatcatctgt
     4981 gttaaaagat tcagcaattc tctgggctgt tttttccagt tccttgatag attttttagg
     5041 agaaatctta ggagcgacag caagaagatt atctgaaaaa tagttcaaaa aagtcccgtt
     5101 gtacttgatt cgtttttcaa tcaggtgata cttgcgactc tgaagattga ccaccaaggc
     5161 ctcgtcagca cccgttccaa atccaggcag gttattctga gtcagcttga ttggattatc
     5221 aacttctcct ccgaggtggg tcaaggtctc ccgcagggca attcgcaaga aagcgaaatg
     5281 ttctacacct tctttagaaa attgaacaaa aatcaagtca ttggtcttga gattttcaga
     5341 aatgctaaac tcctctttcc agagattagc cagcgttact gatgtctcca acaaatcgtc
     5401 tgtaatatga ttgaagaagg gattttcttc ttcgaaaatc ccagtcttgg cttcatctga
     5461 atacacatgt tcaatttttt tacgtaggta ttcttcgatt tttggagtaa tattgagaaa
     5521 cttatctgct aagaacagct cggtatcatc cggactgaac tggtgaataa tggctttctt
     5581 aatataaatg tccataaaag ttttattcct cgtataatgg gaaggcatct gtcaattctt
     5641 tgactgcact tctcacttct tctaatacag cctcattttc tgaattctta agggttttaa
     5701 tgatgagttc agccactttg cgactttctt cttcaccaaa tccacgtgca gtaatagctg
     5761 ctgctccgat acgaatccca cttgtcttga atggtgacaa ggtttcgtaa gggattgaat
     5821 ttttatttag ggtaatattg acttcatcca gcaagttttg agcaactttt ccgttttcta
     5881 caaccttagt cacatcaaca aggaagagat ggttttcagt tccacctgaa ataatacgga
     5941 aatcagggtc ttgcaagaag acatctgcca tagccttgct gttcttaatt acattggcag
     6001 catattcctt gaaggctgga tccaaaactt ctttgaagga aactgcctta gccgccacaa
     6061 catgctctaa aggaccgccc tgaatacctg ggaaaatagc tgaattgatt tttttagcaa
     6121 gttcttcgtc attggtcaaa atcaaaccac cacgaggtcc acgaagggtt ttgtgggtcg
     6181 ttgttgtagt gatatgagcg tatggcactg ggcttgggtg aagaccagct gcaaccaagc
     6241 cagcgatgtg ggccatatca accataagct tcgcaccgac agcatctgcg atttcacgga
     6301 attttgaaaa gtcaataatt tgagaatagg ctgaagcacc agctacaatc agttttggtt
     6361 ttacttcttg ggcttgtttc aagatagcat caaagtctaa gagttccgtt tcaggatcaa
     6421 cactataaga aacaaagttg taggtttgac cagagaagct aacaggagcc ccatgagtca
     6481 aatgaccacc tgatgccaaa tccattccca taaccgtatc acctggctca atcaaggaca
     6541 tgtaagccgc acagttggcc tgacttcctg agtgaggttg gacattggca aatttagcac
     6601 cgaaaatttc ttttgcgcgt tcaatagcaa gagtctctac aacgtctact acatcagttc
     6661 caccataata acggcgtcct gggtaaccct cggcatattt atttgtcaag atagaccctt
     6721 gagctgccat aacagccttg gaaactacgt tttccgaagc aattaactcg atattatttt
     6781 gttggcgttc ttcttctttg gcaatagcat tccagagatc agcatcatat gctttaaaat
     6841 catctttgtc aaaaatcata ggtcttctcc tttattgtgt gactagtcca ttagtttgat
     6901 tttacaataa gaaaatcaaa ctaaaagatg cgaataaacc gtttctgcat tttatcacaa
     6961 gtatagccaa ctttttcata aaatgcatga gcacccagac gatgattggc agaatttaag
     7021 cggataaacc cataaccaca tcttttggct tcttgttcca acccttgtag taaactttta
     7081 ccgatacctt gaccttgcgc ttgaggtgaa actgctaaag ctaagatatt aaatcctgct
     7141 ttggaataga gtgattcgta aacttcagcg tggacatatc caagtaagac atgattagct
     7201 gcatcctcat agccaagtag gaaatgatgg gaatcctgag acagtctagc tagttggcta
     7261 gccgtttcct ctggactaaa agtataaccc aaagcctctt ggttgatgtc acatatcgct
     7321 ttcacatctg tttcttgcaa atctcttagc atttcaagcc tcctcaaaag aaatctctgg
     7381 caaccgagca agaatatctt ctcgtttaat tgcgccttgg cgtaagattt tcaccttgtc
     7441 tccagacaaa tccacaatag ttgaatcctg tccagttaga aaagcatcgt cttccagacc
     7501 cagaacctct tggtcaaaat ccttcagaat ttgttcaaag gttacaccac ttgcctgacc
     7561 tgagatattg gcagacggcc caatcaaggg acctgtctct cgaattaaat ccagtgtgat
     7621 agggtgactg ggcatccgaa atccaatagt tgcaaggtca gaatttaccc aatagggaac
     7681 tcggtcattg gcttcgagaa taatggtcaa gggacctggc aaaaaggtct ctacaagttt
     7741 ttgtagataa gttggctgat tcttagaaaa gtgcaagata tcctcgaaag aggcgatatt
     7801 gagattgagt gccttatctc taggacgacg tttgagttgg taaacatggt caactgcttt
     7861 ttcatctaag gccttggcaa aaagaccata aacagtctct gtaggtagaa cgacagctcc
     7921 accattttcc aactcttgtc taatcctgtc catcatcaac cacaaccatc ctattttgac
     7981 caaattggtc tttgagtgtt cgaacttttt tttcaggaag atgttttcta aaaagttcgg
     8041 gaacactttg accttgcttg tatccaattt caaggtaaat cttaccacca tccttgagat
     8101 agtcttttgc atcttccgca attctacagt aaatagctag gccatcctcg tctgcaaaga
     8161 gagctagatg aggctccgaa tgcaaaacat tcaagcctac ctctgactca tcttcacgag
     8221 agatataggg tggattggat acaattatat catatttttc agaaatttct gcaaaacaat
     8281 cagatttttt aaaaaatata ttaagatttt gatcgctagc attctctgat gcaagctcta
     8341 aggcctcttg agaaacatct gctgctgtca ctgaccaatc tggtctattt tttgctagag
     8401 cgagagcaat agctccacta cctgttccaa tatccagaac tgagagattc gtctcaagat
     8461 tttcagttag aataagctcc actaactcct ctgtttctgg acgaggaatc aaaacccgtt
     8521 catccacctt taaatgcatt ccataaaaat ctgcctgtcc aatgatgtac tgagctggct
     8581 tgtgagctgc tagttgctgg taaatatctt ctacaaattg tttttcttcc tctgttgtca
     8641 cctcctgctg gagggcaaaa ataaagtctg taaaagatag atttttcaga ctacgataga
     8701 caaaagagag gctttccgct tcctctcctt gtcttatcaa ctcttcttca aaatttgaaa
     8761 ataattgagc taatttcatt atttgtttaa ttcttctagt ttttgtgttt ggtcataaag
     8821 caccaaggca tccacaactt cgtccaattt accagacaaa atcgtatcta gtttttggag
     8881 ggtcaagccg atacggtggt ctgtgacacg gttttgaggg aagttataag ttcggatccg
     8941 ttctgaacgg tcaccagtac cgattgtcga cttacgctca gcgtcttgtt catcctgagc
     9001 aatctgagca aagtggtcag cgacgcgtgc acggataatc ttcatagcct tctcacggtt
     9061 cttctgctgg gtacgttctt cctgcatctc aaccttgata ttggttggca agtgaacgat
     9121 acgaacggca gtcgcaacct tattgacgtt ctgtccacca gcacctgatg cgtggtaaat
     9181 atcaacacga agatcttttg gatcgatatc gtattctact tcttcgactt caggcatgac
     9241 aagaactgtg gcagttgagg tatgaacacg accttggctt tctgtcacgg ggacacgctg
     9301 cacacggtgg gcacctgatt cgtacttaag cttagagtat acagactgac ctgaaaccat
     9361 agcaaccact tctttaaacc caccgacacc attcatagag gcttccatga cttcaaagcg
     9421 ccagccttgg gcttccgcat acttttggta catagttagc aaatctccag cgaaaagtgc
     9481 cgcttcgtct ccaccagctg ctccacggat ttcaaggatg atattcttgt catcgtttgg
     9541 atcctttgga aggagcaaaa ttttcagttt ttcttcatat tcttcttttt cagccttggc
     9601 atctttgagt tcttgcttgg ccatttcttc caagtccgca tctccgcctg attccttaat
     9661 catctcttcg gcatcgacga tattttgaag gacttgttta tactcacggt aggctattac
     9721 ggtatcacga ttggaagctt cttcttttga aagctccata aaacgcttgg tgtctgaaac
     9781 gacatcaggg tcactcagca attctcctag ttcttcataa cggtcttcta cagcttgtag
     9841 ttgatcatag atgttcattt ttcttcattc tccttattga tttcaggggc aaaataatgt
     9901 ttacggcaaa ccgagatata ggtttcatta ccaccaattt ggatctgttc tccatcgtaa
     9961 acgggcagtc catcctgtgt tcgcaacacc atggtcgcct ttttcttgca atactgacag
    10021 atggtcttga tttcgtcaat cttgtctgct aaaagcaaga gatatttgga accttcgaac
    10081 aattcattgc gaaagtcatt tttcaagcca aaagccatga cgggtatgtc taactcgtcc
    10141 acaacacgag ctaggtcata aacatggtgg cgtttgagaa actgggcttc atcgaccaac
    10201 acacagtaag gtttttctgg taggcctcgg atatagccaa agatatccgt tgtttcctca
    10261 atcgcaaggg cagggcgttt catgccaatt cgactcgaca catagccaac accgtcacgc
    10321 gtatccagag ctgaagtcat aatcacaaca ccttttcctt gctcctcata gttataggcc
    10381 accttgagaa tctcgattgt ctttccagag ttcatggtcc cataacgata atacaactgt
    10441 gccatgtttc ttgcttcacg tccatttcta aatttttgct acattctagt atatcataat
    10501 tttcttaagc tttaaacggc aaaatgtggt aaaatggaag aaatcaaaac tagtggagga
    10561 agctattatg ccatttgtac gcatcgattt atttgaagga cgcacgctcg agcaaaagaa
    10621 agctcttgct aaggaagtaa cggaagcagt tgtccgcaac actggagccc ctcaatctgc
    10681 tgtccatgtc atcatcaacg acatgccaga aggaacttac ttcccacaag gggaaatgcg
    10741 tactaaataa gctagcttaa gcagaattgc ttaggctttt tcaatctcca agtagcattc
    10801 attgaagaaa tatcctaaat ttgttacaat ttgaaaagaa acttggagaa tttccaagaa
    10861 aagagctatt aattaaagga aacattatga ttacacgtga atttgatacc atcgctgcta
    10921 tctctactcc actaggtgaa ggggctattg gtattgtccg cctgagcgga acagacagtt
    10981 ttgctattgc gcaaaagatt tttaaaggaa aagacttgaa caaggttgcc agccacactc
    11041 tcaactacgg tcacattatt gatcctctga ctggtaaagt catggacgag gttatggttg
    11101 gggctatgaa gtctccaaag accttcactc gtgaggatat tatcgagatt aacacccacg
    11161 gtggtattgc ggtgaccaat gagattctcc agctagctat ccgtgaagga gctcggttgg
    11221 cagaacctgg tgaatttacc aaacgtgcct ttttaaacgg tcgcgtagat ttgacacagg
    11281 ccgaggcggt gatggatatc atccgcgcca agacagacaa ggccatgaac atcgcggtca
    11341 aacaacttga tggttccctt tctgatctta tcaataatat ccgtcaagaa atccttaaca
    11401 cacttgccca agttgaggtc aatatcgact atcctgagta tgacgatgtt gaggaagcca
    11461 ctactgctgt tgtccgagag aagacaatgg agtttgagca attactaacc aagctcctta
    11521 ggacagcacg tcgtggtaaa atccttcgtg aaggaatttc aacggctatc attggacgtc
    11581 ccaacgttgg gaaatcaagc cttctcaaca acctcttgcg tgaggacaag gctatcgtaa
    11641 ccgatatcgc tgggacaaca cgagatgtca tcgaagagta cgtcaacatc aatggtgtac
    11701 ctctcaaatt gattgataca gctggtattc gtgaaacgga tgatatagtg gaacaaatcg
    11761 gtgttgagcg ttcgaaaaaa gccctcaagg aagccaactt ggttctacta gtgctaaatg
    11821 ccagtgaacc actgactgcg caagacagac aacttcttga aattagccaa gataccaatc
    11881 gcattattct acttaataaa accgacctgc cagaaacgat tgaaacttcg aaactacctg
    11941 aagacgttat ccgtatttca gtccttaaaa accaaaacat cgacaagatt gaagagcgaa
    12001 tcaacaacct cttctttgaa aatgctggct tgattgagca agatgctact tacttgtcaa
    12061 acgcccgtca catttccctg attgaaaaag cagttgaaag cctacaagcc gttaatcaag
    12121 gtcttgagct ggggatgcca gttgatttgc ttcaagttga cttgactcgt acttgggaaa
    12181 tcctcggaga aatcactggg gatgctgctc cagatgaact catcacccaa ctctttagcc
    12241 aattctgttt aggaaaataa gaaaaatcca tgatccttca ttcggtcatg gattttattg
    12301 tctttattag taatctggtc ttaagacccc tgttacagtt gccttagttg cttcgtagtc
    12361 gccatctacg acaaccttga taatgcgttt ggcatcttct tctggtgctg gaacaagagg
    12421 tagacgagtg ggtccagctt caaatcccat atagttaaga attgccttaa ctggagcagg
    12481 acttggataa gagaagagag cattaacctt aggaatgaat ttacgctgaa ttgctgcggc
    12541 tttcttcata tcgctttctg caatggcagt aaacatctcg tgcatttcat ccccatttgt
    12601 atgagaggca acagaaataa ccccatccgc cccaaggttc atggcatgga aagcatctcc
    12661 atcctcacct gtataaatca agaactcttc aggcttgtgc tcaatcaagt aagccatatt
    12721 agccaagcta gtacattctt tgacaccgat aatatttgga tggtcagcca agcgaagcat
    12781 ggtttctgga gtcaattcga caactacacg ccctggaatg ttatagataa taattggtag
    12841 gtcagaagca tctgcaatag tcttaaagtg ctgatacatc ccttcttgag aaggtttgtt
    12901 gtagtaagga acaatagcaa gcccagctgc gaaaccacca aattccgcta cttctttgac
    12961 aaactcaata gagtcacgcg tatcattagt acctacaccc gcaatcaaag gaacgcgtcc
    13021 attgacaacc ttttgtacag ccgcaaacaa ctccaactcc tcatcgtggg tcaaagttgg
    13081 actctcagca gtcgttcctg cgagaagaat tccatccgta tgatgggcca ataaatgctc
    13141 aatcaaggct ggaatagcat caaagttaat agaaccatcc tcatgaaagg gggtaataaa
    13201 ggctgtaatg attttacatt cttttaaatc ttgataagac atgaaaacac ctctctattt
    13261 caaagaagga gttcatctga actcctaaac gatatgacta ttttaattca aatttcaatt
    13321 cggctgttgg acgaaccaat ccacgttcat gaagagtttc agcaatctga actgagttcc
    13381 aagcagcacc tttgagaagg ttatctgaaa caacccacat gtgaattcct ttttctgcat
    13441 ccaagtcttt acggatacga ccaacaaagg tatcacgcga accaactgca ttgatagctt
    13501 gaggatagat ttgatgagct acatcatctt caagaacagc acctgggaag gctgcgatag
    13561 ctgcttttac ttcttcgatt ggagccactt cttttgtttc gatataaaca gactcagagt
    13621 gagctgacaa gactggaata cgcacacatg ttgcagatac tgcaatgcta tcatcttcca
    13681 taattttctt agtttccttg gtcatcttca tctcttcgta cgtgtaatca ttatcagtga
    13741 aaacatcaat ttgtggaaga gcgttaaagg cgataggata atgtttcttg tcaccacctg
    13801 aaggcaaaat ttccgcatgc aaatcacatg gtttcacacc atcattcaag acttcacgaa
    13861 gttcacgttg tgtctcaaga attgctccca taccagcacc tgaaacggct tgataagttg
    13921 aaacaatgat acggtccaag ccccattttt ggcgaaccgg ctcaagagcc accatcattt
    13981 ggattgttga acaattaggg caggcaatga ttccgttgtg ggcatcaagt gcatgagcat
    14041 tgacctctgg aacaaccaaa ggaacatctg gattttgacg gaaataagat gtattatcca
    14101 ctactaccac gccagctttt actgcgtatg gtgcatactt agctgatgta gaactacctg
    14161 ctgaaaagag agcaatatca actccttcaa aagctgtttc agtcgtttct tcaattgtaa
    14221 tatcttgatc tttaaatttc aatgacttac ctgctgaacg tgcagaagca aggtaacgga
    14281 ttttatcgat tggaagtgtt gattcttcca acatttttat catctgagca ccgacagcac
    14341 ctgtcgcgcc gactacagca actgtatatc ccataaataa cctctttcgg aattttctaa
    14401 aaatttctat aatagaagta ttatactact ttttccatga attgcaaagc tttttcatca
    14461 ttttttggaa aataaaaatc ccagtcgcta gactagggac taagaggcat cttcatgtga
    14521 tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc ttatgctcaa
    14581 tagtagtccg aagactacct atcgactcat cgcatattct atattactag agatacttga
    14641 ttttgtcaat aagaaatttt ttcgatcgag tataacaaaa aactctcgta ttcaagagtt
    14701 tccctataca tatcatgcta attgccggga tcgaaccggc gacctcatcc ttaccatgga
    14761 tgcgctctgc caactgagct aaatcagctt acttaagaag tatactatat tcagaaaaac
    14821 ttgtcaagtt tccttagaaa ttttccatag gaaaaagcca ggtaagaact acctagctta
    14881 tcttcttcta tttacttaaa tcaattcgac gaccaatttt accaataata atcgccccaa
    14941 taatcaatga agcaaattca ccgattcctg ttgtaaacca agtaaggaag aatggtaatt
    15001 ctgctacaat atttaactct gcagcgatag taaacatgga aattgaaaag aggattgaaa
    15061 agaagaaatg atcttttcga atcaatccgt taaagaggta atccttgcta tattttgcaa
    15121 aaagccaaac acctaaactg aggaatacta aggttgaacc accaccaaca aagacatcta
    15181 gcagtccgaa gctaaagaaa ttagcaatca tacaaccgat ggtaactccg atgatgtact
    15241 taggattgta aaaagccata aagttcatca tttctgaaat acgaaactga taagcaccat
    15301 agctgatggc atttaggggc ggtgtgacag tcaaaacgac gtagatagca gcgacgattg
    15361 caatatctgc aatatcacga atagttaatt ttttcatctt ttctcctttg gcggttgccc
    15421 gcgtgtaata tgcttggtga aagaagctaa gcaccaaggg ttgctttatt caaccctact
    15481 agtatagcac aatagcctgc tttatgctat acttaacaca tgaaaattcc tattcaaaaa
    15541 ttttttaaca atgaaatctt agcctatctc ttttttggcc ttgcgacaac tctagtttcg
    15601 attctctcac gactagtcat ttatcaacta agtcatcagg aactcctggc tactgcccta
    15661 gcaaatatta tcggtatcct atttgccttt atcacaaatg atacgattgt atttaagcaa
    15721 aaaaagaaaa atagacttat ccgtttagtg aaattttctc ttgctcgcct ttctactttt
    15781 ctgttagact tgtttttaac ttttctcttt gtaacccaat ttcctcacat tatagggcaa
    15841 ttcgtaactg aaaacattga taagataaat gctattgaaa caataattgc acaaatattc
    15901 attattatca tcaattatat attgagcaag gcctatattt ttagaaaata atgctccatt
    15961 tatgagcctt ttaattgcct tctataatga tttaggatac aatgaaacac gaaacattga
    16021 aaggaaaaca gtatgttaaa aaatctaaaa tcgttcttgc ttcgaggaaa tgttattgac
    16081 cttgctgtcg gtgttgtaat tgcctctgct tttggtgcta tcgttacttc acttgtaaac
    16141 gacattatca ctcctcttat tttaaatccc gctttgaaag ctgctaaagt tgaacgtatc
    16201 gctcaacttt cttggcatgg agtcggctat ggtaacttct taagtgctat tatcaatttt
    16261 atctttgtgg gtaccgccct cttctttatt atcaagggca ttgaaaaagc acagaaactg
    16321 actggcataa agaaagaaaa aactgccgaa aaaaaaccaa ccgaattgga agtccttcaa
    16381 gaaataaaag ctctccttga gaaaaaataa tcgattaaaa ggatctagcg caaagctaaa
    16441 tccttttttc tttactcttt gggtaacttg cctgcttttt caagcatttt tttgatcaga
    16501 taaggcatct taacattctc ccgccctttt ttctcaatca gttttttcac aaattctggc
    16561 atttgtaaat cttcagattc agctaaaatg tttttcgtct cgtctgaagg aactaactca
    16621 tcaaaggtct cttcttctgg gagaaattcc ttaaactctt gattttcatt gactctaact
    16681 gtattgacca aagcatcaat caaacgagaa tctgtatttg gcattggtgg acgatggtag
    16741 tttaccccaa attcctggca taagtcataa cattctacat cattgtcaaa caagacctca
    16801 atatgctcac tgatgaaact aataggtaca aaaatataat ggtctggatg ttctgtctgt
    16861 tctctgagat actccaaaac atctggttta atccatggaa taccaatatc actctcactc
    16921 tgccaagtgt tggtatattg ttctgaactc aagcccagtt tttcagcgac tagcttgcta
    16981 ttttcgaaaa tttggtctat ataaggatca ccaaagtcca aggcaaaaat gggcacacta
    17041 tgggctgaaa agatgacttt aaagctgtct tgctttactt cttcttttaa aatcttagca
    17101 atttcatctg cccaatagtt taagagcact tcttcctgat accagtcctt aatgaccaaa
    17161 aattgaattt gtttgctttc taaaaatttt tcatagccca tgacagagta gaaagaataa
    17221 tggggctcca aaatcaagca gatacattct tcaacaccat cagtttccat ctgcttgatc
    17281 acgtctggaa taaagggacg agaaaatttg ttggcaaagt agataccgta ctcctcccct
    17341 aaacgttctt tgactaaatt gacctcctca cgtgtaatcc gctgcaaagg cgtcccaccg
    17401 atacgaatat agttgtcata gagagtctgg atttcgtggt cttggggtct aactccacga
    17461 cgaatgtttg taaagaattc tgctactcct tcaaaactaa tctcctctgg agatccaaag
    17521 gtcatcatta atatggcttt tttcatgtta tcatccttat gatattattt tctctatcca
    17581 ttctatcatg aaagaaaaaa atagtaaacg tttcctacgt ctactatttc ttttgctctt
    17641 ttgttttttt atctcgtctt ataattagga tgataaggac aagaagtaag aggacgataa
    17701 taaggagtag aaaggctaga atgtaaatcc aatgactggg aattccgtga tcgaaatacc
    17761 gtgttcctac tgcttcccca ctttcatcct gtgctacttt caccggtgca tccgttattt
    17821 tagctaaaag gatatgtcgt ccattagtta tgttaaggaa acatctcgct tgtacttggc
    17881 tttacttagc agatattgat agtaagcctg gtgttcctca tccttggaac tcaaggttcg
    17941 ataaatctcc gtgtcatagg catccacttc taaaatccca aaaatttcaa gaccacgttc
    18001 tcgaccattg tagtagatag aaccgtagcg atgctggtcg aagaattcct tatcagcaaa
    18061 tttcttaatc tcaccgaaca tagcccctga agccatagag tgtccgtaga tgatcgtatt
    18121 aaaatcagta aagttgggat taaagcgata gtcgagaaaa attgatccca ttatcgtata
    18181 atcgccaaag gcattgcggt caaggtattt gacattatcc tgactttgta gaagcggata
    18241 gtctaccttg gtcccatcaa ggctaatcca accgcaaaca tctttgttca agtgctgtag
    18301 ggtttcaaaa cctgtgctcg aagcatcctt ttcaatagga ttatagtgat catagtcact
    18361 tgcttctact actctctgcc aactaaaaag agctacaaaa acacagaaga ataccagaaa
    18421 tacgttttta aatcgcgctc ttttttgaac cgtcatcagc actcctttct atgcgagatt
    18481 tcttaaaagg aaaggaggcg ggacaaaacc gcctcttttc tattcaccct tagtcagtaa
    18541 aagggtctgc ttcttgcatt ttttttactc tctcttctac gacgtaggat caagtagagg
    18601 acaaggagta agaaaatcaa gagcaagaac aatacaaaca agataaggta ccaaatccat
    18661 agtgggattg atgagaggaa acgtccaaga gacgagtcat caaagacact gtatggaaat
    18721 ggttttgatt tttttgtatg gaaagtattt ttagggacgg tgtctgtaat ctttgcgact
    18781 acgatatgac gaccattggt cacatcgaga aaacaggtac tgagtaggat gatacgatca
    18841 ctcggtgaga gtgagatatc ccgcttgtgc atggcgactg agagcaggtg gtctagatag
    18901 gcctgctggc ggtcctcacc ctgtattcct ggatcataga tgttaaagtc ataggcatca
    18961 acctccaaca tctcaaagat ctcgagccct ttttccacac cattgtagta tatactaccg
    19021 taacgatgct ggtcaaaaaa ttcctgatca gcaaacttag ccacatcacc aaacatgacc
    19081 ccattttcta cgtggtgccc gtagataatg gtattaaagt cttcgaactt aggattattt
    19141 cgtgcatcga gaaagatagc gcctgtcgct gcaaactcac ctttggagtc cttgttgaga
    19201 tacttttcat tgtccttggc ttggactaag ggatagtcga tattggtgcc atagacattg
    19261 atccaaccga ggacttcggg attgagttct tggagtttgc tgaagcctga aaaactggcc
    19321 agctcatcct gttgcgtcgt gacaggtcga taagcttcgt actcacttga cgaagctaag
    19381 gagtagactt ggttggaatc ccaaagggcg tagaaaccaa agagaaagat caaagctgca
    19441 aaaatgagca gcaagtgatt gatcacccca tccacagcaa gaacgagacg cctagacaga
    19501 ctcttttttg gtttctcacg cttggttttc atcatctgcc cccagccgtt taggcttctc
    19561 tacgtttttt agacaagaca acaaatccag ccaaaccaag accaatcatc aaaatgaatg
    19621 gaaggttatc aatcaagaga ccagtaggag taacgtcgtc gattttgtta gtaactttgt
    19681 tgtcgttttt cttttcacct atgaggatat ctgttaatgt aaaatctaca tttttttgtc
    19741 cttgagatgt ttgttctgca ccatttgtag tataaattga tgaatctgta taacctgcta
    19801 ctccagtttc agttactgta tatttagaac ctgctggtag ttgttcaact gtaaatgttt
    19861 caccatcttt aagagtaaaa ttgtactcaa ctgtatctgc tggggtcact actgccaaca
    19921 cctctgactt agatccatgt tttactataa tattcgtaac aggggtttct gctgttttat
    19981 ttgtacttgg aagttgaatc ttgatatgga attggaaatc tcttgtttta tcccctgaag
    20041 ctccatcaac ttttttagta attgttaatg ctttcgcatt ggggtctact tgactcggat
    20101 catcaggatt aggctcctta cttgcgtctt tggtatatgt gttatcaaat aaattataaa
    20161 cgccttgttc acttggttct actttagggg cgttagattt attattttcc ttaaagtata
    20221 ctgatgaaat atagacacca ccatttactt tattcttaac aataacgtgc atttcatatg
    20281 tacgtttgtc gtatctcatg gcatcaattg ttttaccatt tttggtaatc gcctgccatc
    20341 cagtttttgc ttccgctaca tcataaacgt attcaccagc atggccataa gcaactcccg
    20401 aaaaaatgtc ttctgttgct ttttgaatct tatcagcagt tgggtgatca tttttattgt
    20461 attctacatt tctatctgga attgcaactc cggtttgata tggcgcaccg ttagaagatt
    20521 gtcctgtttt ttctgtaaac ttaaatgtaa atgtcgctgt tggtgttgtt attccctctg
    20581 caatattcaa cgttttatta atcttcacaa cagcattatt ttcaccattt gctttggtta
    20641 ttgctgaatt atcatccgca aaagtcggga cacctctgaa tacggacaaa gcggttatag
    20701 ctgcaatgct tgcagtgaat agctttttaa agaatgtttt tttcatgatt atttcttttg
    20761 tttttttatt ttcttttttc attatgatca tcaaaagcct cgtcttctaa tgactgttac
    20821 aactttgcct tgagtatcct gtatagggat ggttccaaaa gcacgactgt ctacagccgt
    20881 tgttcgattg tccccgagga caaaaagttg tcctgctggg actttcatcg ggaaggttgc
    20941 cccttcctta tagagcagcg tttctttgta gatatcttgc tcttgttgag gagaaccgtt
    21001 gatgatgaga ccattttcgt ttatatcgat tgtacttcct tcggttgcta tgacacgcgc
    21061 cactctttcc ttacctttat aactatagac tagcaaatca ccaatcgaat agcgtttatc
    21121 caacctataa tagacgacca agtcgccatc ttttaaggcg ggcttcatgc catcgtcatt
    21181 gtatcttaat aatccaaaga cgaaaaagta aaggatggct agtacaaatc caaccatcag
    21241 aagtttactg actaagtaaa ggatatctcc ccagacactc ggcggagact tatcccgatt
    21301 gacttgtgtt actggtttct tatgtttctt tttaagcagc atcacttcct cctattcacc
    21361 acaaggtgac caagtaagat gataaagaag atccctccta gaggaagaac gactccaagc
    21421 acgagagtgc tactcaagaa gtcaattccc gtttcaggta cgctgttttt attattcgtg
    21481 actgtcgcag acttatttgc atcaagagtt ccttcttttt tatcatagga cacctgatac
    21541 ccacgagacg aacttgcttc ttcttcgata ctataacgag catttagagg aaggtcgaga
    21601 atcttgatgg ttttatcttt ctttagatca actgtcgcct taccattggt gaattgtagc
    21661 gttgtttttt gattatttac tattgcacta tacgatccat tcaatggttt attttgcgca
    21721 tcctttacgt taatggtaat cttaaaggat tgcagaagat tagcaaaagc acctgtaact
    21781 ttttttgtga ctgaaagtgt cggaagtctg tggttggtga cgattgtttg aacatcctct
    21841 gacaaagtcc cctcttgttt ttcataggtg acatgatatc ccgttctaga gttctctact
    21901 tcttccacct tatagtgggt atcacgaggc agataactga gggcagtttc ctgactattt
    21961 ttgagagaaa tctgtgcttt cccgttagtc actgttgtat tcccaaactt gccgttaatc
    22021 ggcttgccat ccttatctga aaaggtaaca ttaattgtga aagatttatt aggtgattgt
    22081 tcaccttcta ggattttctt tacggtgaga cttggaagct gtcggtaaat aactttgaag
    22141 gatggtttct ctttcgtacc tgtcttttga acttcgactg tgtatcccgg agcgtctggt
    22201 gctttcagtt cgtagtcata tcccttagct acctttgcaa aactagtatt ttcagtaaaa
    22261 ctattcgttt gaactggact agtgaccttt cgataggaat cctttatact tccatctttc
    22321 ttttggttta agtttaattc gacactaggt ggacgatttg ctgatggatt tgattttcca
    22381 tccacacctt tccactcaat ctctacagga accgtcaatg gatctgacgg cttgaaagtg
    22441 ggcttctcag aatagtcttt tattttggta cgtgaggtcc caataccata ggaataggca
    22501 acttttgccc ccttgttgga gtagagttta gtagcatcgg cttcttcggc atcatcacta
    22561 gtaagtgtct tatcacccgc aatcgcatca aatgcctctt ggctagaggt gacagtaaac
    22621 ttgagaacgt acttggcgtc atcctccaaa gtgtaactcg gattaaactt ggctgttact
    22681 tccactaatc cctgttcgtt cttcttagtt tcaatcgtaa cttgattgtc attcagttct
    22741 tgctcgttac catccttgat tttgacgaca cgaaggtgtg aagcatcacc aggtaacagc
    22801 tgcacgtact tggacaagac atctgatata gttacatggt gtacgcctag aggtagaatt
    22861 ttatctgtga tttctttgaa tttttgttgc aagtcatttt cattattggc agaaaatatt
    22921 tcgttgggga ttccagaatt ataaccactg atatatcctt taagagatgt gatactatcg
    22981 tttgaaccta tataatatct gaatttgatt gaataaaagc catctatttt tggagctatt
    23041 aaactagata tattcagcat tcctctttct aaaccagagg taaaccaata tggagtatca
    23101 atcatacgtc ccacatttgg attagaataa tagttatata ttgttctccc actattagac
    23161 tcgtaataca tattagcttc gccatctgac agcagaataa ctactttttt tgccccagcc
    23221 cttgcacttt gcaacaatct ttgagcttca gttaacccag catttatatt tgtcccagtg
    23281 ccaatgcccg cgtccatacc ataagaacga ctagagtcag caattgttaa cgaactaaca
    23341 atattttttg agctattaga atccgtgctc caagatacta aagttttagc atcatcatat
    23401 gaagagatat ttgaatacca accagctcaa tttggccaag ttccatattg ataactcaga
    23461 taatattcat tataataacg gtcattatac tgattatcaa tctttccggc aaaaccaact
    23521 atagacagac ggttttggga attagaaaga attgtatcaa tgagcccctg acgaccattc
    23581 acacctttca gtgtatgttt tagtgcttca atcctactaa tgtatcgtct actagagtaa
    23641 gaccacacat ctcgctcttc catactccct gaaagatcgg caaccaagac tacatccaag
    23701 ggttctgact gggtctccgt tcccagttta gatgtgatat ccagtgacaa ctcatactgg
    23761 tctttttgcc ctgatatcgg agtaatcgtt ttgtgcagag ttgtctgagg ttcagttatt
    23821 gaatctgcac gtaaagaatt aattggtgca cacaaaaaaa gaatagcgag aaagataact
    23881 aaactactgg taaaatattg aatcttctta aaatcatatt gaacgttcat gctatctccc
    23941 ttgctagaat atgttttaat ctgatactat ataaatctga gacttccata agataattgt
    24001 ataataatat taacttcgtg tcaattaatg tgtttgaaaa catgttatta taaattacaa
    24061 aaaagtatga ttcttctttg tttttcaact ttttctgtgg taaaatggaa aaaatagtaa
    24121 aaaatttcat aaaataaaga tgcatatatt tattctaatc gctcgaaaat ttcttttgaa
    24181 agtcttctga atttgaatta ttatattttt tcaaaattca taaaatttct caaatcatat
    24241 ttttccgaag ttttgtattc tattttatga taaaaaagga gtttttttat gacttatcca
    24301 aatctcttgg accgcttctt aacctacgtt aaggtcaaca cgcgctctga tgaacactct
    24361 actactactc caagtacaca gagtcaggtt gacttcgcaa caaatgtcct aattcctgaa
    24421 atgaaacgtg ttggactgca aaatgtttac tatctaccga atggttttgc tattggaacc
    24481 ttgccagcca acgatccgtc tttaacacgt aagattggtt ttatatcgca catggatact
    24541 gctgatttta atgctgaagg agtcaatcca caggtaattg aaaactacga tggtggtgtg
    24601 attgaactag ggaattctgg tttcaaactc gatccagccg acttcaagag tcttgaaaaa
    24661 tatccaagac aaacactcat cacaacagat ggaacaacct tgctaggtgc tgatgacaag
    24721 tcaggaattg ctgaaattat gacagccatt gaatatctaa ctgctcatcc tgaaattaag
    24781 cactgtgaga ttcgtgttgg ttttggtcca gatgaagaaa tcggtgttgg tgccaataaa
    24841 tttgatgcag aagattttga tgtggatttt gcctacactg ttgatggtgg tccactaggt
    24901 gaacttcagt acgagacttt ctcagccgct ggtgctgaat tgcatttcca aggccgtaat
    24961 gtccaccctg gtactgccaa agggcagatg gtcaatgccc ttcagctagc aattgatttt
    25021 cataatcaac ttccagaaaa tgaccgacct gagttaactg aaggttacca aggtttttac
    25081 catctaatgg atgtgacagg tagtgttgag gaggtgcgtg caagctacat cattcgtgat
    25141 tttgaaaaag atgcctttga agcgcgtaaa gcatccatgc aatctatcgc tgataagatg
    25201 aatgaagaac ttgggagcga ccgtgtcact ctcaacttga cagaccagta ctacaatatg
    25261 aaagaagtca ttgaaaaaga tatgactcca attaccattg ctaaagccgt tatggaagat
    25321 ctaggtatca cgcctattat cgaaccaatc cggggtggaa cagacggctc taagatttcc
    25381 tttatgggaa tcccaactcc gaatatcttt gcaggtggcg aaaatatgca cggacgtttt
    25441 gaatacgtta gccttcagac tatggaacgt gcagttgata ccatcattgg catcgtagct
    25501 tataaaggct aaaaagacga ggtggctcag ctacttcgcc tttcttttta ttctactggt
    25561 ttttcttgat ttccagtagt tgtagaagat tctgttgttt cattttctga agttgattca
    25621 gcaggtttag aatctcttgt attgcttggt ttgttttcgt cgctagcagt ttcaatgtta
    25681 gattctgcag ttgcgtttgg ttggttctca gcactggtgt tatcactatt tgcttcagca
    25741 tttcttgctg gacttgtttc ttcacttgcg ctaacttttg actggatttg atgattcaaa
    25801 actagaatag cttttgtcga ttcaagtaaa gctgttttgt ctttactatt agcagaaagt
    25861 tgatctaata atgcatccac cttatcaaag tccgcatcag atccattatt actttctaaa
    25921 taagagtgaa gcgacatgag aatatcgtag agtttttgat agagtacaag tgtctgagaa
    25981 tcttgctcag cattttcctt ttcttgttga agggcgctag cgatacgagt caaaacatct
    26041 tttacctgac tgtttacttc atccaagtct gcatcagcct tgtttgtggc agcttttaga
    26101 ttttctactt cttctgccaa ggattgtctg attccttctt catggatttg ttccaagagt
    26161 tgatttgcct tgttcaaaag actttctact tcttccttgc tatctgtcgc agattattgg
    26221 ttgctatcta ccatgtactc ctaaaacagg agagttataa tccaagatta caaggcctta
    26281 cagaaataag aaatccagat aagacaatgt tcgtccaaga cgctattcgc ttcgcacagc
    26341 agcacggatt caatatgctt taattttaaa gtttaggtgt caagacctct ttttagtgtg
    26401 cccaaaattt agagaagtaa tcaatcaact aacttttatt tttttcaaac tttcagtaaa
    26461 ctgacctaaa gctaactcaa tctgtctttg tagatgcttc tgctatcagc tagaagttga
    26521 tctacttttg ccaagactgc cttctcatca aaagttccag gttgatagtt ggattgcagg
    26581 gatggaatct tgtttttcaa agccgcttca tatcccttag tttgaacctt gatgtagtga
    26641 ttgtggtcgc catgaggaat cacaaaacct tctgaatctt cacttataat tcgattggca
    26701 tcaaaaacca taaccatctt cttcctcatg gtggacatgt agtgacggat tacttaatac
    26761 agaactagaa gaacttccta cctcttccgt gttagagtgt gatgggggat tgttaagaga
    26821 tgacttagga atatagtgat agtgttcccc atgtcttact atataagcat cacctatatc
    26881 tctgacaata tcattagggt taaagacata tgtggctgct aattcacctg ccgacaagtc
    26941 actctcagga atgaaatgat agtgaccacc atgtggtact attagtagat tgaaatagaa
    27001 tatgagcaaa ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga
    27061 tgtgctattc taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt
    27121 aattttgcta cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt
    27181 tggcgattga tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa
    27241 acataatact ttccatctac cttaataata tatcctccct taacctaact gacaatatct
    27301 tgatctttcg gctgatagtt gggggctttc attaatggct cttcactaaa gagcgcatca
    27361 aaaggaactt taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga
    27421 tctgtaatct taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct
    27481 ggagtcaaat tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt
    27541 ttatctgtat tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa
    27601 aggataacaa cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt
    27661 ctataattat ttatatgatg tcttcattat taaatgatta tagaaattaa ttaaccaatt
    27721 aattaactag taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta
    27781 ataataaaat gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca
    27841 tttttgattc agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt
    27901 tttatcactt ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca
    27961 ctatctaagc ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct
    28021 actgctggag cttcctctaa tgctggatct aacatagggt cactccccac attcccttct
    28081 ggattcaaca ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc
    28141 tctggtaaag aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat
    28201 acttttccat tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa
    28261 tctgccatat tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc
    28321 atattaaaca agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt
    28381 tcttgtacag gatccactgt aggaacttct tctaacgttg aattactagt actattccca
    28441 gtttcagaaa gtttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca
    28501 tcaagttttg agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta
    28561 tcagtttgat tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc
    28621 aaataagcat ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct
    28681 tggtttaatt tcggaatcgg taatttgatt tcaccaactt tatagttatt ttctaaataa
    28741 gcatttccat gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca
    28801 aattgagggt tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga
    28861 ctggccattt tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct
    28921 ggataatctt ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct
    28981 aattcaaagt ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc
    29041 aatacttttc catctggtgt tattaatttt actagcatat tgatacctaa ttttttctcc
    29101 aattcaggcg gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga
    29161 ttattaaacg tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa
    29221 actttattcc cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg
    29281 tgagaatgac caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct
    29341 ccatgcggat aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca
    29401 ccatattgtt tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt
    29461 tctttggcat tacttggata atcctgttca tgagatgaca aagaatctaa tccattatga
    29521 ctagttttaa cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc
    29581 ttcttgaaga aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca
    29641 gcgataatac gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt
    29701 cctggattga ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt
    29761 tgcccaattt gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa
    29821 gctgtagccg tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa
    29881 gagagctcct tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac
    29941 actacttcat taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc
    30001 attctggcaa tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg
    30061 tcgccatgcg gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag
    30121 accaggccat ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa
    30181 agactctgga gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat
    30241 tgcgtgttat tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt
    30301 ccagccagat gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg
    30361 tagtgatagt gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca
    30421 gctggattaa agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca
    30481 acattagagt taaccttctc attatctttg acatgttctt gtttttgacg attgatttca
    30541 tctttagttc gaacattatc agcatgagct gcatctttca ggtagacata atattttcca
    30601 tcgaccttga tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga
    30661 tagtttggat ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca
    30721 ttatagtaat gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt
    30781 acaatttgct cggcctgaat tccttctttc tggctaatct ggtctggtgt caagttttca
    30841 cttttctgac ttgactggct gccatctaca taagagacac gattattgtc cttattttcc
    30901 tgcgaacgat gctggtttag tgcataggca catagactca aggatacgat aacagctgat
    30961 ccagctgcta tatatttttt actgaatttc ataaatccct ca
//
LOCUS       DAVAZV010000020        30975 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVAZV010000020 DAVAZV010000000
VERSION     DAVAZV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30975
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.020"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..194)
                     /locus_tag="VQT46_000906"
     CDS             complement(<1..194)
                     /locus_tag="VQT46_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2370953.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVRE"
     gene            189..443
                     /locus_tag="VQT46_000907"
     CDS             189..443
                     /locus_tag="VQT46_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2370954.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGDHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
     gene            787..2121
                     /gene="trmFO"
                     /locus_tag="VQT46_000908"
     CDS             787..2121
                     /gene="trmFO"
                     /locus_tag="VQT46_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET2370955.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRIFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEAIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            2205..2942
                     /locus_tag="VQT46_000909"
     CDS             2205..2942
                     /locus_tag="VQT46_000909"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET2370956.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            2951..3508
                     /gene="frr"
                     /locus_tag="VQT46_000910"
     CDS             2951..3508
                     /gene="frr"
                     /locus_tag="VQT46_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET2370957.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            3568..4422
                     /gene="cvfB"
                     /locus_tag="VQT46_000911"
     CDS             3568..4422
                     /gene="cvfB"
                     /locus_tag="VQT46_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET2370958.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            4431..4646
                     /locus_tag="VQT46_000912"
     CDS             4431..4646
                     /locus_tag="VQT46_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET2370959.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            4732..5700
                     /locus_tag="VQT46_000913"
     CDS             4732..5700
                     /locus_tag="VQT46_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET2370960.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            5880..6380
                     /locus_tag="VQT46_000914"
     CDS             5880..6380
                     /locus_tag="VQT46_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370961.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            6383..6643
                     /locus_tag="VQT46_000915"
                     /pseudo
     CDS             6383..6643
                     /locus_tag="VQT46_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(7010..8121)
                     /gene="ald"
                     /locus_tag="VQT46_000916"
                     /pseudo
     CDS             complement(7010..8121)
                     /gene="ald"
                     /locus_tag="VQT46_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            8298..8867
                     /locus_tag="VQT46_000917"
     CDS             8298..8867
                     /locus_tag="VQT46_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2370962.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            8935..9585
                     /locus_tag="VQT46_000918"
     CDS             8935..9585
                     /locus_tag="VQT46_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET2370963.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            9569..11809
                     /locus_tag="VQT46_000919"
     CDS             9569..11809
                     /locus_tag="VQT46_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET2370964.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSLQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVASRPLVFGQPNEWLLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLTKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIKKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDKEHVGDL
                     SEMTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMIVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            11989..12177
                     /locus_tag="VQT46_000920"
     CDS             11989..12177
                     /locus_tag="VQT46_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370965.1"
                     /translation="MTVTKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            12209..12796
                     /locus_tag="VQT46_000921"
     CDS             12209..12796
                     /locus_tag="VQT46_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2370966.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            12800..13975
                     /locus_tag="VQT46_000922"
     CDS             12800..13975
                     /locus_tag="VQT46_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370967.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILALFVSVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWKDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVDLNWSMGMVLLPCLIIFLLLGILFIERWGSSQKKRIF"
     misc_feature    14149..14280
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            14296..14826
                     /gene="infC"
                     /locus_tag="VQT46_000923"
     CDS             14296..14826
                     /gene="infC"
                     /locus_tag="VQT46_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET2370968.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            14859..15059
                     /gene="rpmI"
                     /locus_tag="VQT46_000924"
     CDS             14859..15059
                     /gene="rpmI"
                     /locus_tag="VQT46_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET2370969.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            15111..15470
                     /gene="rplT"
                     /locus_tag="VQT46_000925"
     CDS             15111..15470
                     /gene="rplT"
                     /locus_tag="VQT46_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET2370970.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            15528..15908
                     /locus_tag="VQT46_000926"
     CDS             15528..15908
                     /locus_tag="VQT46_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET2370971.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            16158..16958
                     /locus_tag="VQT46_000927"
     CDS             16158..16958
                     /locus_tag="VQT46_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET2370972.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVNQRVCEDGPVFRTGTVVL"
     gene            16921..17907
                     /locus_tag="VQT46_000928"
     CDS             16921..17907
                     /locus_tag="VQT46_000928"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET2370973.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            17949..19850
                     /locus_tag="VQT46_000929"
     CDS             17949..19850
                     /locus_tag="VQT46_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HET2370974.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMTANEWIWDKESWFYLKSDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     AKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDSDGEKLSYISQGSVVWL
                     DKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYESDGHRFYHYVAQNASIP
                     VASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNYSAEELDKVFSLLNINN
                     SLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKDKNNFFGITAYDTTPYL
                     SAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEYASDPYWGEKIASVMMK
                     INEKLGGKD"
     gene            complement(19911..21566)
                     /gene="pavA"
                     /locus_tag="VQT46_000930"
     CDS             complement(19911..21566)
                     /gene="pavA"
                     /locus_tag="VQT46_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET2370975.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            21671..22168
                     /gene="ybeY"
                     /locus_tag="VQT46_000931"
     CDS             21671..22168
                     /gene="ybeY"
                     /locus_tag="VQT46_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET2370976.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLGYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            22149..22544
                     /locus_tag="VQT46_000932"
     CDS             22149..22544
                     /locus_tag="VQT46_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET2370977.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFGFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            22561..23460
                     /gene="era"
                     /locus_tag="VQT46_000933"
     CDS             22561..23460
                     /gene="era"
                     /locus_tag="VQT46_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET2370978.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPDRFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            23509..24333
                     /gene="mutM"
                     /locus_tag="VQT46_000934"
     CDS             23509..24333
                     /gene="mutM"
                     /locus_tag="VQT46_000934"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET2370979.1"
                     /translation="MPELPEVETVCRCLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQGCVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            24333..24938
                     /locus_tag="VQT46_000935"
     CDS             24333..24938
                     /locus_tag="VQT46_000935"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET2370980.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFWQEIILENGELNRPLLASLIFSNPDEREWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            24925..26124
                     /locus_tag="VQT46_000936"
     CDS             24925..26124
                     /locus_tag="VQT46_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HET2370981.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSEQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            26124..26273
                     /gene="rpmG"
                     /locus_tag="VQT46_000937"
     CDS             26124..26273
                     /gene="rpmG"
                     /locus_tag="VQT46_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2370982.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            26313..26546
                     /gene="secG"
                     /locus_tag="VQT46_000938"
     CDS             26313..26546
                     /gene="secG"
                     /locus_tag="VQT46_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET2370983.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            26648..29002
                     /gene="rnr"
                     /locus_tag="VQT46_000939"
     CDS             26648..29002
                     /gene="rnr"
                     /locus_tag="VQT46_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET2370984.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKEYHK
                     IVSSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSHSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            28965..29432
                     /gene="smpB"
                     /locus_tag="VQT46_000940"
     CDS             28965..29432
                     /gene="smpB"
                     /locus_tag="VQT46_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET2370985.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            29448..30308
                     /gene="tehB"
                     /locus_tag="VQT46_000941"
     CDS             29448..30308
                     /gene="tehB"
                     /locus_tag="VQT46_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET2370986.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEDVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            30381..>30975
                     /gene="coiA"
                     /locus_tag="VQT46_000942"
     CDS             30381..>30975
                     /gene="coiA"
                     /locus_tag="VQT46_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET2370987.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQG"
BASE COUNT         9196 a         5733 c         7093 g         8953 t
ORIGIN      
        1 tattctcgca catattgaag agtggccata agaaggtctt ctaggcttaa tttaggtttt
       61 cgtccacctt ttgcgtgttt aagttgataa gctgttttta atacagctaa tatctcttca
      121 aaagtcgtgc gctgaacacc aacaagacgc ttaaatcgtg catcagttag ttgtttactt
      181 gcttcataat tcatagaact actataccat attttgtttc gcaggaagtc tattggaaag
      241 taagaaatat tggagctgag gcgattagaa gaaattgtga gcgtggtgct attttttcag
      301 gtaaaataaa acatcacgaa gattctcagt ttaaaggaga ccactatgtt gaatgttatg
      361 ctgttttaga taatacggtt atagcaagag atagaataac agtccctatc gatccgttat
      421 gtggaaaaga ttttatagag tagcatataa ttgattctta actggaatac tctctatctc
      481 tttacatcaa gaaaatgact aaacagggaa gtttgccttc ttcccttttt ttgttatact
      541 agtagaagaa aaaaatagaa agatttgtgg gagtgaaaaa gtccggggga ctttttcagc
      601 ttgagccaag aaattcgaga gcgaggaaag tccgggggac tttttcagcc tgagccaaga
      661 aattcgagag cgaagtaagt ccaatggact ttttcagcct gagccaagaa actcgaaagc
      721 tcgtaagtct gattggcttt ttcaatgtga atcttaactt cacactccca aagaggtatt
      781 agtgtcgtgt ctcaatctta tatcaatgtt atcggtgctg gtttggcagg ttctgaagca
      841 gcttaccaaa tcgcagagcg tggtattcca gttaaactat atgaaatgcg tggtgtcaag
      901 tcgactcccc agcataaaac agacaatttt gctgagttgg tttgttccaa ttctttgcgt
      961 ggggatgctt tgacaaatgc agttggtctt ctcaaggaag aaatgcgtcg cttgggttct
     1021 gttatcttgg aatctgctga ggctacacgt gttcctgcag gtggtgccct tgcagtggac
     1081 cgtgatggtt tctctcaaat ggtgaccgaa aaagttgcca accacccctt gattgaagtg
     1141 gttcgtgatg aaattacaga attgccgaca gatgttatta cggttatcgc tactggtcct
     1201 ttgacaagtg atgccttggc tgaaaagatt catgccctta atgacggtga tggtttttat
     1261 ttctacgatg cggcagcgcc tattatcgat gtcaacacta tcgatatgag caaggtctac
     1321 ctcaaatcac gttatgataa gggagaagcg gcctacctca atgcccctat gaccaagcaa
     1381 gaatttatgg atttccatga agctttggtc aatgcagaag aagcaccgct taattctttt
     1441 gaaaaagaaa agtactttga aggctgtatg cctatcgaag tcatggccaa acgtggcatt
     1501 aaaactatgc tttatggccc tatgaagcca gtcggtcttg agtacccaga cgactataca
     1561 ggacctcgtg atggagaatt taaaacacct tatgcggttg tgcaacttcg tcaggacaat
     1621 gcagctggta gcctctacaa tattgttggt ttccagaccc acctcaaatg gggagaacaa
     1681 aagcgtatct tccaaatgat tccgggtctt gaaaatgcag agtttgtccg ttatggtgtc
     1741 atgcatcgca attcttacat ggattcacca aatcttcttg agcagactta ccgttctaag
     1801 aaacaaccaa atctcttctt tgctggtcag atgacggggg tggaaggcta tgttgagtcg
     1861 gcggcttcag gcttagttgc gggaattaac gcagctcgtc tcttcaagga agaaagcgag
     1921 gctattttcc ccgagacgac agcgattgga agcttagctc attacattac ccatgccgac
     1981 agcaaacatt tccaaccaat gaatgtcaat tttgggatca tcaaggagtt ggaaggcgag
     2041 cgtatccgtg ataagaaggc tcgttatgaa aaaattgcag agcgtgccct tgccgactta
     2101 gaggaatttt tgactgtcta atttttttga aagaattgct catgatacta taaaaatctt
     2161 agaaattgtg ataaaatagg taggatgaaa gaaggagagt gaaaatggcg aatcccaagt
     2221 ataaacgtat tttaatcaag ttatcaggtg aagcccttgc cggtgaacgt ggcgtaggga
     2281 ttgatatcca aacagttcaa acaatcgcaa aagagattca agaagttcat agcttaggta
     2341 tcgaaattgc ccttgttatt ggtggaggaa atctctggcg tggagaacct gcagcagaag
     2401 caggtatgga ccgtgttcag gcagattaca ctggaatgct tgggactgtt atgaatgctc
     2461 ttgtgatggc agattcattg caacaagttg gggttgatac gcgtgtacaa acagctattg
     2521 ctatgcaaca agtggcagag ccttatgtcc gtggacgtgc ccttcgtcac cttgaaaaag
     2581 gccgtatcgt tatctttggt gctggaattg gttcaccata cttctcgaca gatacaacag
     2641 cggcccttcg tgcagctgaa atcgaagcgg atgccatcct catggctaaa aatggtgtcg
     2701 atggtgttta caatgccgat cctaagaaag ataagacagc tgttaagttt gaagaattga
     2761 cccaccgtga cgttatcaat aaaggtcttc gtatcatgga ctcaacagct tcaaccctct
     2821 caatggacaa cgacattgac ttggttgtct tcaacatgaa ccaatcaggc aacatcaaac
     2881 gtgtcgtatt tggtgaaaat atcggaacaa cagtttcaaa taatatcgaa gaaaaggaat
     2941 aagaaagaat atggctaacg caattattga aaaagctaaa gagagaatga cccagtctca
     3001 ccaatcactt gctcgtgaat ttggtggtat ccgtgctggt cgtgccaatg caagcttgct
     3061 tgaccgtata catgtagaat actatggagt tgaaactcct cttaaccaaa tcgcttcaat
     3121 tacgattcca gaagcgcgtg ttttgttggt aacaccattt gacaagtctt cattgaaaga
     3181 catcgaacgt gccttgaacg cttctgatct tggtatcaca ccagctaatg acggttctgt
     3241 gattcgcttg gttgtcccag ctcttacaga agagactcgt cgtgaccttg ctaaagaagt
     3301 gaagaaggtc ggcgaaaatg ctaaagtggc tgtccgcaat atccgtcgcg atgctatgga
     3361 cgaagctaag aaacaagaaa aagcaaaaga aatcactgaa gacgaattga agactcttga
     3421 aaaagacatt caaaaagtaa cagacgatgc tgttaaacac atcgacgata tgactgccaa
     3481 caaagagaaa gaacttttgg aagtctaaaa ataaacagaa aaactcagtt ggcattgctg
     3541 gctgagtttt attcgaaaga aggaaatatg aatacaaatc ttgcaagttt tatcgttgga
     3601 ctgatcatcg atgaaaacga ccgtttttac tttgtgcaaa aggatggtca aacctatgct
     3661 cttgctaagg aagaaggcca acatacagta ggggatacgg tcaaaggttt tgcatacacg
     3721 gatatgaagc aaaaactccg cctgacaagc ttagaagtga ctgccactca ggaccaattt
     3781 ggttggggac gtgtcacaga ggttcgtaag gacttgggtg tctttgtgga tacaggcctt
     3841 cctgacaagg aaatcgttgt gtcactcgat attctccctg agctcaagga actctggcct
     3901 aagaagggcg accaactcta catccgtctt gaagtggata agaaagaccg tatctggggt
     3961 ctcttggctt atcaagaaga cttccaacgt cttgctcgtc ctgcctacaa caacatgcag
     4021 aaccaaaact ggccagccat tgtttaccgt ctcaagctat caggaacttt tgtttaccta
     4081 ccagaaaata atatgcttgg ttttattcat cctagcgagc gttacgcaga gccacgtttg
     4141 gggcaagtat tagatgcgcg cgttattggt ttccgtgaag tggaccgcac tttgaacctc
     4201 tccctcaaac cacgctcctt tgaaatgttg gaaaacgatg ctcagatgat tttgacttat
     4261 ttggaaagca atggcggttt catgacctta aatgacaagt catctccaga cgacatcaag
     4321 gcaacctttg gcatttctaa aggtcagttc aagaaagctt taggtggtct tatgaaggct
     4381 ggtaaaatca agcaggacca gtttggtaca gagttgattt agggaggctt atgagaaaat
     4441 cattttacac ttggctcatg accgagcgca atcctaaaag taacaatccc aaagcaattt
     4501 tggcagacct cgcttttgaa gaggcagctt ttccaaaaca tacagatgat tttgatgagg
     4561 tcagtcgctt tttggaggag catgccagtt tctcttttaa cctaggagat tttgacagca
     4621 tttggcagga atatctagaa cactagcatt tattcattgg gtttgggcta gtaatttctc
     4681 catccctctg ctataataaa aagaaataaa aggattagag aggttcttta tttgaaggaa
     4741 cattcaatag acattcaact gagtcatcca gatgacctgt ttcatctttt tggttccaat
     4801 gaacgccatc ttcgtttgat ggaagaagag cttgatgttg tgattcatgc tcgtacggag
     4861 attgtccagg ttttgggaga agagtctgct tgcgaggaag cccgtcaggt tattcaagct
     4921 ctcatggcct tggtaaatcg tgggatgacc gttggtacgc cagatgtagt gacggctatt
     4981 agtatggtca aaaatgatga aattgacaag tttgtcgccc tttacgaaga agaaatcatc
     5041 aaggataata ctgggaagcc tatccgcgtc aaaaccttag gtcaaaaact ttatgtggac
     5101 agtgtcaaac agcatgatgt gacctttgga attgggccag caggtacagg gaagaccttc
     5161 cttgcagtga ccttggcagt gactgccctt aaacgtgggc aagtcaagcg aattatccta
     5221 actcgtccag cggtggaagc gggagagagt cttggatttc ttccgggtga tcttaaggag
     5281 aaggtggatc cttaccttcg tcctgtttac gatgccttgt atcaaattct tgggaaagac
     5341 caaacgactc gtctcatgga gcgtgaaatt atcgaaattg cgccccttgc ctatatgcgt
     5401 ggccggacct tggatgatgc ctttgtcatt ctcgatgagg cgcaaaacac gaccatcatg
     5461 cagatgaaga tgttcttgac gcgtttaggc tttcattcta agatgattgt caatggagat
     5521 atcagtcaga ttgacctgcc acgtaatgtc aagtccggtt tgattgatgc tcaagagaaa
     5581 ctcaagaaca tccatcagat tgactttgtt catttttcag ccaaggatgt ggttcgccat
     5641 ccagttgtcg ctcagattat ccgagcctat gaatattcta ctgaagttgc acacgactga
     5701 ttttgaggaa gttcgcctgc aaaagaatat acttttgaga gaggaaaatc cagttgtata
     5761 ggctaaaggt ttgagacaac gattaggcac gatggaaaga acttttatgt ggctgatgac
     5821 gatcagtgca tcttcctgtg tcataatcac agggcacaag aaagtaggaa tttgaaaaga
     5881 tgattgacca actatctaag tattacagtt gtaggatact aactgaaaag gatattccaa
     5941 gtattttatc tttatatgaa agtaatcctc tgtattttca gcattgtcca ccagagccaa
     6001 attttgcaac tgtaaaagag gacatgcttt gtctacctga aggtaaagct aaggctgata
     6061 agttttttgt tggattttgg aatggctctg accttgtggc tgttatggat tttgtctatg
     6121 catatcctga tgaggagact gtttttattg gtttgtttat ggttgatcaa gcctatcaga
     6181 ggaaagggat tggtagtcat attgtgacag aagcactagc ttattttgct aagaactttc
     6241 gaaaggcacg tttggcttat gttaagggaa atccgcaatc tcagcatttt tgggaaaagc
     6301 agggctttaa atcaattgga tgcgaggtta agcaagaact ctatacggtt gttatcgctg
     6361 aacagagcct agaagattag aaatggcatc aagtaagaac tatttggaat ttgttttgga
     6421 acaattatca ggattagatg atgtgactta ccgttccatg attggggagt atattcttta
     6481 cttccgcggc aagattattg gcggcattta tgacgatcgc tttttagtta aacccgtgca
     6541 agcagtctta gataagattg accaatcttc ttttgagttt ccatacaaag gtgccaaaga
     6601 aatgatttga gtggaagaac ttgataataa gatgtttcta taagacctga ttttagctat
     6661 gtataaccaa ctgccaacgc ccaaacctaa aaagaaaaag caagggtgaa cgaagtaaaa
     6721 aagaagtctg ctaaggccct gtctttgcac gggtaaaatt ttatatataa aaagaagctg
     6781 ggactaaaga gctcagcttc ctttggttta tataattgtc attacaagac gaagtggttg
     6841 ggcgaaactc tgttgacttt attcaattta gagtttctta tgcacaattg agtctggaac
     6901 gaaagtctcc agttgcaaag tatacagtac aataaaccaa cgatgtaata gctgatgaca
     6961 caaagcacag tgggtaggac ttgcgaagtc acccttttct tttcaaaatt tatactaaat
     7021 cattgatatc agtgtagtca cgattaagtc cttgagcaac tggtaggcta gtcaagtaac
     7081 cttgataagt ggtcacacct tgacgcaagc cttcatcttc agagattgct tgtgcgaatc
     7141 ctttgccagc caaagcttcg atataaggaa gagtgacatt ggttagggcg atggttgaag
     7201 tgcgggcaac cgcaccaggg atattggcaa cggcatagtg gagaacaccg tgtttttcat
     7261 agacgggttc atcgtgcgtt gtcacacggt cagctgtttc gataacgcca ccttggtcaa
     7321 cagcaacgtc aacgatacag agcctggacg catttgtttg accatctcat ctgtcaccaa
     7381 ttccggtgct tttgcaccag ggatgagaat ggctccaatc accacatcag catctctcac
     7441 acttgcttca atgttgaatg aattagatat aatagtttga atttgacttc caaagacttc
     7501 ttctagaact gagagacgct tggcactaat atctaaaata gtcacttgag caccaagacc
     7561 aagggcgatg cgggcagcat gtgtaccgac gacaccatca ccgatgatag ttacttttcc
     7621 ttttggaaca cctggtacac caccaagtag aacaccagag ccaccagctt gcttagtaag
     7681 gaagtgagct ccgatttgaa cagccatacg acctgcaacc tcactcatag gaacgaggag
     7741 cggtagttgt ccttgattgt cacgaacagt ttcataggca attcctgttg tttttgctgc
     7801 taacatagca tctgctaatt ctggagcagc ggccatgtgc aagtaggtga agagaagaag
     7861 atcgtcgcgc aagtaaccgt attcagaact taaaggttct tttactttca caaccaactc
     7921 tgctgcccaa gcttcaccag cagtagcgac aatctcagct ccttgctttt gatagtcagc
     7981 atcagtaaag ccagaaccga gaccagcatt tgtttcgata aggacacgat gaccacgact
     8041 aactaagcta tgaacacctg caggtgtgag ggcgacacgg ttttcgttat ttttaatttc
     8101 ttttgggatt ccgattaaca ttgagataac ctacctttca attgacggtc ttgttttggt
     8161 tgtcacattc cagttcataa atcaaaaatg tgacggtttc attgtatatg aaaccgcttc
     8221 aaaaatcaag aaaaacttgt catccaaatt tttttatgct agactagtga aaatcaagct
     8281 ctaatggagg gaaaagtatg gaatcaatat ttgtgaaatt tgcccagtat ccgtctatag
     8341 aaacggagcg tttattgctt agacctgtaa ctttggatga tgcggaagca atgtttgact
     8401 atgcctcgga caagggtaat acacgttaca cttttccaac caatcaaagc ttggaagaaa
     8461 ccaagaataa cattgctcag ttctacttgg ctaatccctt gggacgttgg gggattgaat
     8521 taaaagataa cggcaagttt atcggaacta ttgacttaca caagattgat cctgttctta
     8581 agaaggcagc tattggctac attatcaata aaaagtattg gaatcaagga ttaacgacag
     8641 aagccaatcg tgctgtgatt gagctagctt ttgagaagat agggatgaat aagttgactg
     8701 cccttcacga taaggctaat cccgcgtcag gaaaggtcat ggagaaatca ggcatgcgtt
     8761 tttcccatgc agaaccatat gcttgtatgg accagcatga aaaaggccga atcgtgacaa
     8821 gagttcatta tgtcttgacc aaggaagact attttgcaaa taaataagca gttgaaaaga
     8881 aatttttcga ctgttttttc ttcctcttac gaataatcta agagaggaga aaatatggaa
     8941 gcaattatcg agaaaatcaa agagtataaa atcatcgtca tctgtactgg tctgggcttg
     9001 cttgtaggag gatttttcct gctaaagcca gctccacaaa catctgtcaa agagacgaat
     9061 ttgcaggctg aagttgcagc tgtttccaag gactcatcga ccggaaagga agtgaacaag
     9121 gaagagaagg aagaaccagt tgaacaagat ctaatcacag tagatgtcaa aggtgctgtc
     9181 aaatcgccag ggatttatga cttgcctgta ggtagtcgag tcaatgatgc tgttcagaag
     9241 gctggtggct tgacagagca agcagacagc aagtcgctca atctagctca gaaagttagt
     9301 gatgaggctc tggtttacgt tcctactaag ggagaagaag cagttagtca acagactggt
     9361 tcggggacag cttcttcaac aagcaaggaa aagaaggtca atctcaacaa ggccagtctg
     9421 gaagaactca agcaggtcaa gggactggga ggaaaacgag ctcaggacat tattgaccat
     9481 cgtgaggcaa atggcaagtt caagtcagta gacgagctca agaaggtctc tggcattggt
     9541 gccaagacca tagaaaaact taaagactat gttacagtgg attaagaatt tctctattcc
     9601 cctaatttac ctgagttttc tattactatg gctttactac gccattttct cagtatccta
     9661 ttttgctttg ttgggttttg tttttctgct agtctgcctc tttatccaat ttccttggaa
     9721 atcagcaggt aaagttctag tgatttgtgg agtctttggc ttctggtttc tgtttcaaac
     9781 ttggcaacag agtcaagtga gtcaaaattt ggtggattct gttgaaaggg tacggatttt
     9841 accagacact attaaggtta acggtgacag tctgtccttt cgtggtaagt ctgatggtcg
     9901 tgctttccaa gtctattata aactccagtc cgaggaggag aaagaagcct ttcaagcttt
     9961 aactgacctt catgagatag gactagaagg gaagctttcg gagccagaag ggcagagaaa
    10021 ttttggtggc tttgactacc aaggctatct gaagactcag ggaatttacc agacactcaa
    10081 tattaaaaga atccagtcac tccaaaaggt tggcagttgg gatataggtg aaaacctgtc
    10141 cagtttacgt cgaaaggctg tggtttggat taagatgcac ttcccagacc ctatgcgcaa
    10201 ttacatgaca ggactcttgc taggacatct ggacaccgat tttgaggaga tgaatgagct
    10261 ttattccagt ttaggaatta ttcacctttt tgccttgtca ggtatgcagg tagggttttt
    10321 catggacgga tttaagaaac tacttttacg attgggcttg acacaagaaa agttgaagtg
    10381 gctgacttat cccttttccc ttatctatgc gggactaact ggattttcag catcggttat
    10441 tcgcagtctc ttgcaaaagc tactggctca acatggggtt aagggcttgg ataattttgc
    10501 cttgacggtg cttgtcctct ttattgtcat gccaaacttt ttcttgacag caggaggagt
    10561 cttgtcctgt gcttatgctt ttatcctgac catgaccagc aaagaagggg aggggctcaa
    10621 ggctgttact agtgaaagtc tagtcatctc cttgggcata ttgcccattc tatccttcta
    10681 ttttgcggaa tttcaacctt ggtctatcct tttgaccttt gtcttttcct ttctttttga
    10741 cttggtcttc ttaccgctct tgtctatctt atttgtcctt tcctttctct atccagtcat
    10801 tcagctgaac tttatctttg aatggttaga gggcattatt cgcttggtct cgcaggtggc
    10861 aagtagaccg cttgtctttg gacaacccaa tgaatggctt ttaatcctat tgttaatttc
    10921 tttggctttg gtctatgatt tgaggaaaaa cattaaaaag ctaacggtat tgtgcttatt
    10981 gattacaggg ctctttctcc tgaccaagca tccactggaa aatgaaatca ccatgctgga
    11041 tgtggggcaa ggagaaagta ttttcctacg ggatgtaact gggaaaacca ttctcataga
    11101 tgtaggtggt aaggcagaat cttataagaa aatcaaaaaa tggcaagaaa agatgacgac
    11161 cagcaatgcc cagcgaagct tgatacccta tctcaaaagt cgaggagtag ctaagattga
    11221 ccagctaatt ttgactaaca cggacaagga gcatgttgga gatttgtcag agatgaccaa
    11281 ggctttccat gtaggggaga ttctagtatc aaaagacagt ctgaaacaga aggaatttgt
    11341 ggcagaacta caggcgactc aaacaaaggt gcgtagtatg atagtagggg agaacttacc
    11401 catttttgga agtcagttag aagttctatc tccaaggaaa atgggagatg gaggacacga
    11461 tgatacccta gttctgtatg ggaaattctt ggataagcaa tttctcttca cgggaaattt
    11521 ggaggagaaa ggagagaagg acttgctgaa gcactatcca gacttgaaag taaatgtttt
    11581 gaaagctagc caacatggca ataaaaaatc atcaagtcca gcctttctag aaaaactcaa
    11641 accagagctt actcttatct cagttggaaa gagcaatcga atgaaactcc cccatcagga
    11701 aacattgaca cgactggaag gtatcaatag caaagtttat cgaactgacc agcaaggagc
    11761 tatacgtttt aaggggttgg atagttggaa aatcgaaagt gttcgatagg aaggataaat
    11821 gttgtagatt agtgaaataa actaaaaatt tgttgcataa taatgataaa aacggcataa
    11881 tgaaaacgta ttcaatattg aggatataaa atcattaaaa atcagcaaaa gttgttttag
    11941 ttagttagtt tataatctat tggtcttctt cagtccagtg tatctgctgt gacagtcact
    12001 aaaagttaca agtatgattg gaatacggtt ttggaatata gtaccaacta tcacgaccat
    12061 cagtatgctt ggattccgga atggtctcgt tattacagct attctgagta taaagttggc
    12121 ggaggctgga actacgctcg ttatgaggtc ataaactact atactggagg ttattaatcc
    12181 ttaaagagtg agaaaaggag ggctggatat gttaaatctt actcatgtta ccttaaaaac
    12241 gcgacaagtc atcttgcaag atgcggattt tacctttaaa aagggtagga tttatggcct
    12301 tcttgctatc aatggctcgg gaaagacgac actattccga gctatgagca agttgcttcc
    12361 ccttagtagt ggacacatcg cagttcctcc ttctttgttt tattatgaga gcgttgaatg
    12421 gctggatgga aacttaagtg ggatggacta ccttcgtctc ataaaaaaca tctggaagtc
    12481 agacctaaac ttgagagatg aaatcgccta ctgggaaatg gctgactata tcagtcttcc
    12541 catccgcaag tattccttag ggatgaagca acgcttggtg attgctatgt attttctcag
    12601 tcaggccaaa tgctggctca tggatgagat tacaaatggc ttagacgagt attatcgaca
    12661 gaagtttttt gataggctag cacaaatcga tagacaagaa cagctggttc ttttaagttc
    12721 ccactataag gaagagttgg ttgatatctg cgatagagta gtaaccattc atcaggggca
    12781 gatagaagag gtttagttta tgaaagatgt tagtctattt ttattgaaaa aagttttcaa
    12841 aagtcgttta aactggatta tcttagcttt atttgtatct gtactcggtg ttacctttta
    12901 tttaaatagt cagactgcaa actcacacag cttggagagc aggttggaaa gtcgcattgc
    12961 agccaacgag agggctatca atgaaaatga agagaaactc tcccaaatgt ctgataccag
    13021 ctcggaggaa taccagtttg ctaaaaataa tttagacgtg caaaaaaatc ttttgacgcg
    13081 aaagacagaa attctaactt tactaaaaga agggcgctgg aaagaagcct actatctgca
    13141 gtggaaagat gaagagaaga attatgaatt tgtatcaaat gacccgactg ctagctctgg
    13201 cttaaaaatg ggggttgacc gcgaacggaa gatttaccaa gccctgtatc ccttgaacat
    13261 aaaagcacat actttggagt ttccgaccca cgggattgat cagattgtct ggattttaga
    13321 ggttatcatc ccaagcttgt ttgtggttgc gattattttt atgctaacac aactatttgc
    13381 agaaagatat caaaatcatc tggacacagc tcacttatat cctgtttcaa aagtgacatt
    13441 tgcaatatcc tctcttggag ttggagtggg atatgtaact gtgctgttta tcggaatctg
    13501 tggcttttct tttctagtgg gaagtctgat aagtggtttt ggacagttag attatcccta
    13561 cccaatttat agcttagtga atcaagaagt aactattggg aaaatacaag atgtattatt
    13621 tcctggcttg ctcttagctt tcttagcctt tatcgtcatt gtggaagttg tgtacttgat
    13681 tgcttacttt ttcaagcaaa aaatgcctgt cctctttctt tcactcattg ggattgttgg
    13741 cttattgttt ggcatccaaa caattcagcc tcttcaaagg attgcacatc tgattccctt
    13801 tacttacttg cgttcagtgg agattttatc tggaagatta cctaagcaga ttgataatgt
    13861 cgatctaaat tggagcatgg gaatggtctt acttccttgc ctgattatct ttttgctatt
    13921 gggaattcta tttattgaaa gatggggaag ttcacagaaa aaaagaattt tttaatagat
    13981 tctagctttc ctataggtag ggaaaataag taaaaactaa catagagagg gaatcaactt
    14041 gattctctct ttttgattcg aaaaccaaac caaaatacaa acacaaactt ttcaaaaaat
    14101 aactttttat cttgacaaga gctagaaaac ttggtatcat ataaaagttg agaaaagcag
    14161 aagtgagagc ttctcgcctt gtgacattaa gttgcctggc cctacggatg aaaagtttcg
    14221 aagaaacgct atcataacgt gcgggcttgt atatttacga gtccgctatt gtttttctct
    14281 aataaaacaa aagaggtgaa aaccatagca aagcaagact tattcatcaa tgatgagatt
    14341 cgtgtacgtg aagttcgctt gattggtctt gaaggagaac agctaggcat caagccactc
    14401 agtgaagcgc aagctttggc tgataacgct aatgttgacc tagtattgat tcaaccccaa
    14461 gccaaaccgc ctgttgcaaa aattatggac tacggtaagt tcaaatttga gtaccagaag
    14521 aagcaaaaag aacaacgtaa aaaacaaagc gttgttactg tgaaagaagt tcgtctaagt
    14581 ccaactattg acaagggtga ctttgataca aaacttcgta atgcacgtaa gttccttgaa
    14641 aaaggaaata aagttaaggt atctattcgc tttaagggtc gtatgattac ccataaagag
    14701 attggtgcaa aagttttagc cgagtttgct gaagcaactc aagatattgc catcatcgaa
    14761 caacgtgcta aaatggatgg acgtcaaatg ttcatgcaat tggcgccagc gactgacaaa
    14821 aaataattgt cagaaagtta aataaaggag aaaaaattat gccaaaacaa aaaacacacc
    14881 gcgcatcagc taaacgtttc aaacgtacag gttctggtgg acttaaacgt ttccgtgctt
    14941 acacttctca ccgtttccac ggaaaaacta agaaacaacg tcgtcatctt cgtaaagcat
    15001 ctatggtgca ttcaggagat tacaaacgta tcaaagcaat gcttactcgc ttgaaataat
    15061 agcttgactg taagtaaaca attctaggaa atatttggag gaaataaaac atggcacgtg
    15121 ttaaaggtgg cgttgtatca cgcaaacgtc gtaaacgtat tcttaaatta gcaaaaggtt
    15181 actatggagc taaacacatc ttgttccgta ctgcaaaaga acaagtaatg aactcttact
    15241 actatgcata ccgtgaccgt cgtcagaaaa aacgtgactt ccgcaaattg tggatcactc
    15301 gtatcaatgc ggcagctcgt atgaacggac tttcatactc acaattgatg catggtttga
    15361 aattggctga gatcgaagtt aaccgtaaaa tgcttgctga cttggctgtt aacgatgcag
    15421 tagctttcac agctcttgca gatgcagcta aagcaaaact tggtaaataa caactgatga
    15481 gactggaaca ggattgtcca gtctttttaa aaataaagga gaaaaatatg gcttcaaaaa
    15541 tgctacacac ttgcttacga gtagaaaatc ttgaaaaatc aatcgcattt tatcaagatg
    15601 cttttggttt taaagaattg cgtcgcagag attttccaga ccatgccttc acgattgtct
    15661 atctaggtct tgagggtgat gactatgagt tggagttgac ttataactac gatcacggtc
    15721 cgtatgtggt tggtgatggg tttgcccata tcgccctcag tacacctgat cttgaggcac
    15781 ttcatcaaga acacagtgca aaaggctatg aagtgactga gccaaatggt ctaccaggaa
    15841 ctacaccaaa ctattacttt gtcaaagacc ctgatggata taaggtcgaa gtcattcgtg
    15901 aaaaataatt tcgtgcaagt taagtagaat attcgttttt tacttgactt tttttagctg
    15961 aaagagtata ctaataaaaa ttcaaccttt aaggggagtc cagagagact cacaaggtgt
    16021 cagataaaag aatagtgcaa ttttctagag gagacttttt gagtgtgctc tcttgtgttg
    16081 tacgatttta actgaggcct tgcactagca aggtcttttc tttatctggt ccccttaaaa
    16141 tttaaggagg aaaagttatg aatcccacat gtaagaagcg tttgggtgtc attcggttgg
    16201 aaaccatgaa ggtggttgca caagaggaaa tcgcgccagc aatctttgaa ttagtcctag
    16261 aaggagaaat ggttgaagcc atgcgagcag gccaatttct tcatctgcgt gtaccagacg
    16321 atgcccatct tttacgtcgt cctatttcaa tttcgtctat tgacaaggca aacaagcagt
    16381 gtcacctcat ttatcggatt gagggagctg ggactgcaat tttttcaacc ttaagtcagg
    16441 gagacactct tgatgtgatg gggcctcagg gaaatggttt tgacttgtct gaccttgatg
    16501 agcagaatca ggttctcctt gttggtggtg ggattggtgt tccacccttg cttgaggtgg
    16561 ccaaggaatt gcatgaacgt ggagtgaaag tagtgacagt cctcggtttt gctaataagg
    16621 atgctgttat tttgaaaacg gaattggctc agtatggtca ggtctttgta acgacagatg
    16681 atggttctta tggcatcaag ggaaatgttt ccgttgttat caatgattta gatagtcagt
    16741 ttgatgctgt ttactcgtgt ggggctccag gaatgatgaa gtatatcaat caaacctttg
    16801 atgatcaccc aagagcctat ttatctctgg aatctcgtat ggcttgtggg atgggagctt
    16861 gctatgcctg tgttctaaaa gtaccagaaa gcgagacggt caaccaacgc gtctgtgaag
    16921 atggtcctgt tttccgcaca ggaacagttg tattataagg agaaaattat gactacaaat
    16981 cgattacaag tgtctctacc tggtttggat ttgaaaaatc cgattattcc agcatcaggt
    17041 tgttttggct ttggacaaga gtatgccaag tactatgatt taaacctttt aggttctatt
    17101 atgatcaagg cgacaaccct tgaaccacgt tttgggaacc caactccaag agtagcagag
    17161 acgcctgctg gtatgctcaa tgcaattggc ttgcaaaatc ctggtttaga ggttgttttg
    17221 gctgaaaagc taccttggct ggaaagagaa tatccaaatc ttcctattat tgccaatgta
    17281 gctggttttt caaaacaaga gtatgcagct gtttctcatg ggatttccaa ggcaactaat
    17341 gtaaaagcta tcgagctcaa tatttcttgt cccaatgttg accactgtaa tcatggactt
    17401 ttgattggtc aagatccaga tttggcttat gatgtggtga aagcagctgt ggaagcctca
    17461 gaagtgccag tttatgtcaa attaaccccg agtgtgaccg atatcgttac tgtcgcaaaa
    17521 gctgcagaag atgcgggagc aagtggcttg accatgatca atactctggt tggaatgcgc
    17581 tttgacctca aaaccagaaa accaatcttg gccaatggaa caggtggaat gtcaggtcca
    17641 gcagtctttc cagtagccct caaactcatc cgccaagtag cccaaacaac agacctgcct
    17701 atcattggaa tggggggagt ggattcggct gaagctgccc tagaaatgta tctggctggg
    17761 gcatctgcta tcggagttgg aacagctaac tttaccaatc cttatgcctg ccctgacatc
    17821 atcgaaaatt taccaaaagt catggataaa tacggtatta gcagtctgga agaactccgt
    17881 caggaagtaa aagagtctct gaggtaaact gcaatcaatc tgttcttgat tttttattag
    17941 tttgtaatat gaatttagga gaattttggt acaataaaat aaataagaac agaggaagaa
    18001 ggttaatgaa gaaagtaaga tttatttttt tagctctgct atttttctta gctagtccag
    18061 agggtgcaat ggctagtgat ggtacttggc aaggaaaaca gtatctgaaa gaagatggca
    18121 gtcaagcagc gaatgagtgg gtttttgata ctcattatca atcttggttc tatataaaag
    18181 cagatgctaa ctatgctgaa aatgaatggc taaagcaagg tgacgactat ttttacctca
    18241 aatctggtgg ctatatggcc aaatcagaat gggtagaaga caagggagcc ttttattatc
    18301 ttgaccaaga tggaaagatg aaaagaaatg cttgggtagg aacttcctat gttggtgcaa
    18361 caggtgccaa agtaatagaa gactgggtct atgattctca atacgatgct tggttttata
    18421 tcaaagcaga tggacagcac gcagagaaag aatggctcca aattaaaggg aaggactatt
    18481 atttcaaatc cggtggttat ctactaacaa gtcagtggat taatcaagct tatgtgaatg
    18541 ctagtggtgc caaagtacag caaggttggc tttttgacaa acaataccaa tcttggtttt
    18601 acataaaaga aaatggaaac tatgctgata aagaatggat tttcgagaat ggtcactatt
    18661 attatctaaa atctggtggc tacatggcag ccaatgaatg gatttgggat aaggaatctt
    18721 ggttttatct caaatttgat gggaaaatag ctgaaaaaga atgggtctac gattctcata
    18781 gtcaagcctg gtactacttc aaatccggtg gttacatgac agccaatgaa tggatttggg
    18841 ataaggaatc ttggttttac ctcaagtctg atggcaaaat ggctgaaaaa gaatgggtct
    18901 acgattctca tagtcaagcc tggtactact tcaaatctgg tggttacatg gcgaaaaatg
    18961 agacagtaga tggttatcag cttggaagcg atggtaaatg gcttggagga aaagctacaa
    19021 atgaaaatgc tgcttactat caagtagtgc ctgttacagc caatgtttat gattcagatg
    19081 gtgaaaagct ttcctatata tcgcaaggta gtgtcgtatg gctagataag gatagaaaaa
    19141 gtgatgacaa gcgcttggct attactattt ctggtttgtc aggctatatg aaaacagaag
    19201 atttacaagc gctagatgct agtaaggact ttatccctta ttatgagagt gatggccacc
    19261 gtttttatca ctatgtggct cagaatgcta gtatcccagt agcttctcat ctttctgata
    19321 tggaagtagg caagaaatat tattcggcag atggcctgca ttttgatggt tttaagcttg
    19381 agaatccctt ccttttcaaa gatttaacag aggctacaaa ctacagtgct gaagaattgg
    19441 ataaggtatt tagtttgcta aacattaaca atagcctttt ggagaacaag ggcgctactt
    19501 ttaaggaagc cgaagaacat taccatatca atgctcttta tctccttgcc catagtgccc
    19561 tagaaagtaa ctggggaaga agtaaaattg ccaaagataa gaataatttc tttggcatta
    19621 cagcctatga tacgacccct tacctttctg ctaagacatt tgatgatgtg gataagggaa
    19681 ttttaggtgc aaccaagtgg attaaggaaa attatatcga taggggaaga actttccttg
    19741 gaaacaaggc ttctggtatg aatgtggaat atgcttcaga cccttattgg ggcgaaaaaa
    19801 ttgctagtgt gatgatgaaa atcaatgaga agctaggtgg caaagattag tactataagt
    19861 gaatatgatt tgagtgaata gtaagttaaa aatcctgatt tcaagtaaaa tcaggatttt
    19921 ttcatggatg caattttttt ggagtctggt gtgacgcgga gggtcttttg tcctgtgtaa
    19981 gtgacaaagc cgggttttcc accagttggt ttattgagtt ttttgacttc aatcatatct
    20041 acctgcacca gattcgacag gcgcccttga gagaagtagg cagctaactc tgctgcgtct
    20101 gtcttgactg catcagatgg gtcaagattt cctgagatga caacatggct tccaggaatg
    20161 tccttagcat ggaaccaaag ttcctccttg cgggccattt taaaggtcaa ttcctcattt
    20221 tgaagattgt ttcgtccgac atagatgatg gttttgccat cgcttgctag atattgttct
    20281 agttttttgc gtttctggat tttctcccgt tgtcttctgc ggataaaacc tgtttgaatc
    20341 aattcttcac ggatttcagc gatttcttcc agtccagctt ggttgaggac ggtttctaca
    20401 ctttccagat agagaatagt ggctttggtt tcttcaatca aatcagtcaa gtatttgaca
    20461 gcttctttga gtttctgata ccgtttaaaa tagcgttggg cattctggtt gggagtcaga
    20521 gccttatcaa gcgcaatcat gataggttgg ttggtatagt agttgtctag gataacctgg
    20581 tcttggtcgt taggcacttg gtggaggaag gttgtcagca attctccttt ttgacgaaat
    20641 tcttcagcgt tgtctgtcgc cagtaactct ttttcctgtt ttttgagttt gtgtcggttt
    20701 ttctgaagtt cattttcaac acgacgaatc agttcactgg cctgctgttt gacgcggtcg
    20761 cgctcagcct tatccttata gtaggtgtcc aacaaatcag aaagatttgc aagaggctct
    20821 cccacctgat ttgcaaaagg aactggactg aaggaagtct cagtcaagca tggcttggtt
    20881 tcttgattga aaaaatttcg gaaagcggaa agtttttcac taaccagtat cctttccaat
    20941 tcatttgccg tatcgcgtcc cagaccttga aagaggcttt gaagattttt tgctgttagt
    21001 tcttgggttt gcaggatttc aaagagcttt tcatccttga tagtaaaagg attgagagat
    21061 tttgtacttg gcggagcgat ataggtcgat cctggaagta aggtgcggta gctattttgt
    21121 gaaaagccga cgtgtttgat aacttcgagg attttatgac tgcttttatc gaccagtaga
    21181 atattactgt gtttccccat aatttcgata atcaaggtag cctggatatg gtctccaatc
    21241 tcgtttttat tggaaactgt aatttccaca atacggtcat tttccacttg ctcaatcgac
    21301 tcaatcaggg ccccctgcaa atactttctc aaaaccatga taaaggtaga aggttgggct
    21361 ggattttcaa aagtcgtttg ggtcagctga atgcgtccaa aaactggatg ggcagaaagg
    21421 agcaggcgat ggctttggcg attgctgcgg atttgcaaga ccaactcttg ttcaaaaggc
    21481 tgattgattt tctggatgcg accattcact aattcgcttc gcaattcctc aactatgtgg
    21541 tgtaaaaaaa atccgtcaaa tgacatcgtt ctctccttgt gattgtattc catagtatta
    21601 tatcaaaaag gtagaataaa atcatggaaa tgtggtataa taaagccaag taaagagaaa
    21661 cgagaagcac atgtatattg aaatggtaga tgaaactggt caagtttcaa aagaaatgtt
    21721 gcaacaaacc caagaaattt tggaatttgc agcccaaaaa ttaggaaaag aagacaagga
    21781 gatggcagtc acttttgtga ccaatgagcg tagtcatgaa cttaatctgg ggtaccgtga
    21841 caccgaccgt ccgacagatg tcatcagcct tgagtataaa ccagaattgg aaattgcctt
    21901 tgacgaagag gatttgcttg aaaatccaga attggcagag atgatgtctg agtttgatgc
    21961 ctatattggg gaattgttca tctctatcga taaggctcat gagcaggccg aagaatatgg
    22021 tcacagcttt gagcgtgaga tgggcttctt ggcagtacac ggctttttac atattaacgg
    22081 ctatgatcac tatactccgg aagaagaagc ggagatgttc ggtttacaag aagaaatttt
    22141 gacagcctat ggactcacaa gacaataaac gaaaatggaa aaatcgtgac ctgatatcca
    22201 gtttagaatt tgccatcaca gggattttta ctgctatcaa ggaagaacgc aatatgcgaa
    22261 aacatgcagt gacggctcta gtggtcatcc ttgcaggttt tggttttcag gtgtcacgaa
    22321 tcgaatggct ctttctccta ttgagcattt tcttggtggt agcctttgaa attatcaatt
    22381 ctgctatcga aaatgtggtg gatttggcca gtcactatca cttttccatg ctggctaaaa
    22441 atgccaagga tatggcggct ggcgcggtat tagtggtttc tctttttgca gccttaacag
    22501 gcgcattgat ttttctccca cgaatctggg atttattatt ttaaacagta agaggaaatt
    22561 atgactttta aatcaggctt tgtagccatt ttaggacgtc ccaatgttgg gaagtcaacc
    22621 tttttaaatc acgttatggg gcaaaagatt gccatcatga gtgacaaggc gcagacaacg
    22681 cgcaataaaa tcatgggaat ttacacgact gataaggagc aaattgtctt tatcgacaca
    22741 ccagggattc acaaacctaa aacagctctc ggagatttca tggttgagtc tgcctacagt
    22801 acccttcgcg aagtggacac tgttcttttc atggtgcctg ctgatgaagc gcgtggtaag
    22861 ggggacgata tgattatcga gcgtctcaag gctgccaagg ttcctgtgat tttggtggtg
    22921 aataaaatcg ataaggtcca tccagaccag ctcttgtctc agattgatga cttccgtaat
    22981 caaatggact ttaaggaaat tgttccaatc tcagcccttc agggaaataa cgtgtctcgt
    23041 ctagtggata ttttgagtga aaatctggat gaaggtttcc aatatttccc gtctgatcaa
    23101 atcacagacc atccagaccg tttcttagtt tcagaaatgg ttcgcgagaa agtcttgcac
    23161 ctaactcgtg aagagattcc gcattctgta gcagtagttg ttgactctat gaaacgagac
    23221 gaagagacag acaaggttca catccgtgca accatcatgg tcgagcgcga tagccaaaaa
    23281 gggattatca tcggtaaagg tggcgctatg cttaagaaaa tcggtagcat ggcccgtcgt
    23341 gatatcgaac tcatgctagg agacaaggtc ttcctagaaa cctgggtcaa ggtcaagaaa
    23401 aactggcgcg ataaaaagct agatttggct gactttggct ataatgaaag agaatactaa
    23461 gtagaggtgg gctcatgcct gcttcttgtt tttacagaag gaggacttat gcctgaatta
    23521 cctgaggttg aaaccgtttg tcgttgctta gaaaaattga ttataggaaa gaagatttcg
    23581 agtatagaaa ttcgctaccc caagatgatt aagacggatt tggaagagtt tcaaagggaa
    23641 ttgcctagtc agattatcga gtcaatggga cgtcgtggaa aatatttgct tttttatctg
    23701 acagacaagg ttttgatttc ccatttgcgg atggagggca agtattttta ctatccagac
    23761 caaggacctg aacgcaagca tgcccatgtt ttctttcatt ttgaagatgg tggcacgctt
    23821 gtttatgagg atgttcgcaa gtttggaacc atggaactct tggtgcctga ccttttagac
    23881 gcctacttta tttctaaaaa attaggtcct gaaccaagcg aacaagactt tgatttacag
    23941 gtctttcaat ctgcccttgc caagtccaaa aagcctatca aatcccatct cctagaccag
    24001 accttggtag ctggacttgg caatatctat gtggatgagg ttctctggcg agctcaggtt
    24061 catccagcta gatcttccca gactttgaca gcagaagaag cgacagctat tcatgaccaa
    24121 accattgctg ttttgagcca ggctgttgaa aaaggcggtt ccaccattcg gacctatacc
    24181 aatgcctttg gggaagatgg aagcatgcag gattttcatc aggtctatga taagactggt
    24241 caaggatgtg tacgctgtgg taccatcatt gagaaaattc aactaggtgg acgtggaacc
    24301 cacttttgtc caaactgtca aaggagggac tgatgggaaa aatcatcgga atcactgggg
    24361 gaattgcctc tggtaagtca actgtgacaa attttctaag acagcaaggc tttcaagtag
    24421 tggatgccga cgcagtcgtc caccaactac agaaacctgg tggtcgtctg tttgaggctc
    24481 tagtacagca cttttggcaa gaaatcattc ttgaaaacgg agaactcaat cgccctctcc
    24541 tagctagtct catcttttca aatcctgatg aacgagaatg gtctaagcaa attcaagggg
    24601 agattatccg tgaggaactg gctactttga gagaacagtt ggctcagaca gaagagattt
    24661 tcttcatgga tattccccta ctttttgagc aggactacag cgattggttt gctgagactt
    24721 ggttggtcta tgtggaccga gatgcccaag tagaacgctt aatgaaaagg gaccagttgt
    24781 ccaaagatga agctgagtct cgtctggcag cccagtggcc tttagaaaaa aagaaagatt
    24841 tggccagcca ggttcttgat aataatggca atcagaacca gcttcttaat caagtgcata
    24901 tccttcttga gggaggtagg caagatgaca gagattaact ggaaggataa tctgcgcatt
    24961 gcctggtttg gtaattttct gacaggagcc agtatttctt tggttgtacc ttttatgcct
    25021 atcttcgtgg aaaatctagg tgtagggagt gagcaagtcg ctttttatgc aggcttagca
    25081 atttctgtct ctgctatttc cgcggcgctc ttttctccta tttggggtat tcttgctgac
    25141 aaatacggcc gaaaacccat gatgattcgg gcaggtcttg ctatgactat cactatggga
    25201 ggcttggcct ttgtcccaaa tatctattgg ttaatctttc ttcgtttact aaacggtgta
    25261 tttgcaggtt ttgttcctaa tgcaacggca ctgatagcca gtcaggttcc aaaggagaaa
    25321 tcaggctctg ccttaggtac tttgtctaca ggcgtagttg caggtactct aactggtccc
    25381 tttattggtg gctttatcgc agaattattt ggcattcgta cagttttctt actggttggt
    25441 agttttctat ttttagctgc tattttgact atttgcttta tcaaggaaga ttttcaacca
    25501 gtagccaagg aaaaggctat tccaacaaag gaattattta cctcggttaa atatccctat
    25561 cttttgctca atctcttttt aaccagtttt gtcatccaat tttcagctca atcgattggc
    25621 cctattttgg ctctttatgt acgcgattta gggcagacag agaatcttct ttttgtctct
    25681 ggtttgattg tgtccagtat gggcttttcc agcatgatga gtgcaggagt catgggcaag
    25741 ctaggtgaca aggtgggcaa tcatcgtctc ttggttgtcg cccagtttta ttcagtcatc
    25801 atctatctcc tctgtgccaa tgcctctagc ccccttcaac taggactcta tcgtttcctc
    25861 tttggattgg gaaccggtgc cttgattccc ggggttaatg ccctactcag caaaatgact
    25921 cccaaagccg gcatttcgag ggtctttgcc ttcaatcagg tattctttta tctgggaggt
    25981 gttgttggtc ccatggcagg ttctgcagta gcaggtcaat ttggctacca tgctgtcttt
    26041 tatgcgacga gcctttgtgt tgcctttagt tgtctcttta acctgattca atttcgaaca
    26101 ttattaaaag taaaggaaat ctagtgcgag taaaaattaa tctcaaatgc tcctcttgtg
    26161 gcagtatcaa ttacctaacc agtaaaaatt caaaaaccca tccagacaag attgaggttt
    26221 taaagtattg tcccaaggaa agaaaagtaa ccctacatct tgaatctaag tagattttat
    26281 ggtaaaataa tagggatttt aaggagtttg atatgtataa cctattatta accattttat
    26341 tagtattatc tgttgtgatt gtgattgcaa ttttcatgca accaaccaaa aaccaatcca
    26401 gcaatgtatt tgatgccagt tcaggtgatt tgtttgaacg tagtaaagct cgcggttttg
    26461 aagctgtaat gcagcgtttg acagggattt tagtcttttt ctggctagcc attgccttag
    26521 cattgacggt attatcaagt agataagaaa ataatgggca ggactaggtc tttgcctctt
    26581 tttattttta aaggatgttt gagaaggttt tacagtaaaa gaaaattaaa aaatctagaa
    26641 agaaaatatg aaagatagaa taaaagaata tttacaagac aagggaaagg tgactgttaa
    26701 tgatttggct caggctttgg gaaaagacag ttccaaggat tttcgtgagt tgattaaaac
    26761 cttgtcctta atggaaagaa agcaccaaat tcgttttgaa gaagatggta gtctgacatt
    26821 agaaattaag aaaaaacatg agattaccct caaggggatt tttcatgccc ataaaaatgg
    26881 ctttggcttt gttagtctgg aaggcgagga ggacgacctt tttgtaggga aaaatgatgt
    26941 caactatgct attgatggtg ataccgtcga ggtagtgatt aagaaagtcg ctgaccgcaa
    27001 taagggaaca gcagcagaag ccaaaattat tgatatccta gaacacagtt tgacaacagt
    27061 tgtcgggcaa atcgttctgg atcaggaaaa acctaagtat gctggctata ttcgttcaaa
    27121 aaatcagaaa atcagtcaac cgatttatgt taagaaacca gccctaaaat tagaaggaac
    27181 agaagttctc aaagtcttta tcgataaata cccaagcaag aaacatgatt tctttgtcgc
    27241 gagtgttctc gatgtagtgg gacactcaac ggatgtcgga attgatgttc ttgaggtctt
    27301 ggaatcaatg gacattgtat ccgagtttcc agaagctgtt gttaaggaag cagaaagtgt
    27361 gcctgatgct ccgtctcaaa aggatatgga aggtcgtctg gatctaagag atgaaattac
    27421 ctttaccatt gacggtgcgg atgccaagga cttggacgat gcagtgcata tcaaggctct
    27481 gaaaaatggc aatctggagc ttggggttca catcgcagat gtttcttatt atgtgaccga
    27541 ggggtctgcc cttgacaagg aagcccttaa ccgtgcgact tctgtttacg tgacagaccg
    27601 agtggtgcca atgcttccag aacgactatc aaatggcatc tgctctctca atccccaagt
    27661 tgaccgcctg acccagtctg ctattatgga gattgataaa catggtcgtg tggtcaacta
    27721 taccattaca caaacagtta tcaagaccag ttttcgtatg acctatagcg atgtcaatga
    27781 tatcctagct ggcgatgaag aaaagagaaa agaatatcat aaaattgtat caagtatcga
    27841 actcatggcc aagcttcatg aaactttaga aaacatgcgt gtgaaacgtg gagctctcaa
    27901 ttttgatacc aatgaagcga agattttagt ggataaacaa ggtaagcctg ttgatatcgt
    27961 tcttcggcag cgtggtattg ccgagcggat gattgagtct tttatgttga tggctaatga
    28021 aacagttgcc gaacatttca gcaagttgga tttgcctttt atctatcgaa ttcacgagga
    28081 gcctaaggct gaaaaggttc agaagtttat tgattatgct tcgagttttg gcttgcgcat
    28141 ttatggaact gccagtgaga ttagtcagga ggcacttcaa gacatcatgc gtgctgttga
    28201 gggagaacct tatgcagatg tattgtccat gatgcttctt cgctctatgc agcaggctcg
    28261 ttattcggag cacaatcacg gccactatgg actagctgct gactattata ctcactttac
    28321 cagtccaatt cgtcgttatc cagaccttct tgttcaccgt atgattcggg attacggccg
    28381 ttctaaggaa atagcagagc attttgaaca agtgattcca gagattgcga cccagtcttc
    28441 caaccgtgaa cgtcgtgcca tagaagctga gcgtgaagtc gaagccatga aaaaggctga
    28501 gtatatggaa gaatacgtgg gtgaagagta tgatgcagtt gtatcaagta ttgtcaaatt
    28561 cggtctcttt gtcgaattgc caaacacagt tgaaggcttg attcacatca ctaatctacc
    28621 tgaattttat catttcaatg agcgtgattt gactcttcgt ggagaaaaat caggtatcac
    28681 tttccgagtg ggtcagcaga tccgtatccg tgttgaaaga gcggataaaa tgactggaga
    28741 gattgatttt tcattcgtac ctagtgagtt tgatgtgatt gaaaaaggct tgaaacagtc
    28801 tagtcatagt ggcagagggc gtggttcaaa tcgtcgttcg gataagaagg aagacaagag
    28861 aaaatcagga cgctcaaatg ataagcgtaa gcattcacaa aaagacaaga agaaaaaagg
    28921 aaagaaacct ttttacaagg aagtagctaa gaaaggagcc aagcatggca aagggcgagg
    28981 gaaaggtcgt cgcacaaaat aaaaaggcac gccacgacta tacaatcgta gatacgctag
    29041 aggcagggat ggtcctgact ggaactgaaa tcaagagtgt acgagctgct cgaattaatc
    29101 tcaaggatgg ctttgctcaa gtgaaaaatg gagaagtttg gctgagcaat gttcatatcg
    29161 cgccttacga agagggcaat atctggaacc aggaaccaga acgtcgtcgt aaactcctgc
    29221 tccataaaaa gcaaattcaa aaattggaac aagagaccaa agggacagga atgaccttag
    29281 ttccccttaa ggtctatata aaagatggct acgctaagct tcttttagga cttgccaaag
    29341 ggaagcatga ctatgacaaa cgggagtcta tcaaacgtcg tgagcaaaat cgagatatcg
    29401 cgcgtgtgat gaaagctgtt aatcagcgat aaaaagagga attgaaaatg gaaaaattag
    29461 ttgcctataa acgcatgcct ttgtggaata aacaaacaat gcctgaagat gttcagcaaa
    29521 agcacaatac aaaagttggg acttggggga aaattactgt cttgaaggga gctctcaagt
    29581 ttattgaatt gacagaagaa ggggaagttc tagctgaaca cctctttgaa gcaggggcag
    29641 acaatccaat ggcccaacct caagcctggc accgagtgga agctgccaca gatgatgtgg
    29701 aatggtactt ggaattttat tgtaaacctg aggattattt tgctaaaaaa tacaatacca
    29761 atcctgttca ttcagaggtc ctagaggcca tgcagacagt gaaacaaggg aaagctttgg
    29821 atttgggttg tggtcagggg cgtaattctc tttttctagc ccagcaagat tttgatgtga
    29881 cggctgtaga tcaaaatgga ctagctcttg aaatcttgca aagcattgtg gagcaggaag
    29941 atttggacat gcctgttggc ctttacgata tcaattcagc tagcattgaa caagaatatg
    30001 attttatcgt ttcaacagtt gttctcatgt ttctacaagc ggaccgcatt ccagctatta
    30061 ttcaaaatat gcaggagaaa accagtgttg gtggttacaa ccttatcgtt tgtgccatgg
    30121 acacggagga ttatccttgc tcggttaatt tcccattcac ctttaaagaa ggagaactgg
    30181 cagactatta caaggattgg gaattggtta agtacaatga aaatccaggc catttgcacc
    30241 gtcgcgatga gaatggcaat cgtattcaac tacgctttgc gaccttacta gctaagaaaa
    30301 tcaagtaaac acacatgaag attaggaatt ttcctgatct tttttctttt ttacgaatga
    30361 tatagaaaag gagggaattc atgtttgttg cgagagatgc taggggagaa ttggtaaatg
    30421 tgttagagga taaacttgag aagcaagcat acacctgccc agcttgtgga ggccagctcc
    30481 atttgcgtca aggaccaagt gtacggacgc attttgccca taaatcctta aaagactgtg
    30541 attttttctt tgaaaatgaa agtccagaac acctggccaa taaggaatcc ctctatcact
    30601 ggttgaaaaa agagacaaag gttcaattag agtacccgct ttcagaactt aaacagattg
    30661 cggatgtatt tgtaaatggc aatctagctc tagaagttca gtgtagtccc ttgcctcaga
    30721 aagtccttaa agagcgaagt gagggatatc gtagtcaggg ttaccaagta ctgtggttgc
    30781 tgggtcaaaa actgtggctc aaggagcgtt tgactcgtct acagcaaggt tttctttatt
    30841 tcagtcaaaa catgggcttt tatgtttggg aattagacaa ggaaaaacaa gttttaagac
    30901 tcaaatacct gatttaccag gatctccgcg gtaaactcca ttatcaaatc aaggaatttt
    30961 cctatggtca aggta
//
LOCUS       DAVAZV010000021        30074 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVAZV010000021 DAVAZV010000000
VERSION     DAVAZV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30074
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.021"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..1100
                     /locus_tag="VQT46_000943"
     CDS             51..1100
                     /locus_tag="VQT46_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET2370988.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAVHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQT46_000944"
     CDS             complement(1200..5042)
                     /gene="spuA"
                     /locus_tag="VQT46_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET2370989.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPGNANASLEKTEEKPAASPA
                     DPAPQTGQDRSSEPTTSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDD
                     VEKPSENWPNGALSFKDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVE
                     KLVPKMNEAWLDQDYKVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQW
                     PDGTDFTATGKYGRYIDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQ
                     IFLKDDDESIYTNPYYVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHL
                     GNKVTITDVAIDEAGKKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGK
                     LGADLKEEGKQVDLTLWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDST
                     NKLGITDFTGYYYQYQIERQGKTVLALDPYAKSLAAWNSDDSKIDDAHKVAKAAFVDP
                     AKLGPQDLTYGKIHNFKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDY
                     LKDLGVTHIQLLPVLSYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSD
                     PKNPEKRIAEFKNLINEIHKRGMGAILDVVYNHTAKVDLFEDLEPNYYHFMDADGTPR
                     TSFGGGRLGTTHHMTKRLLIDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARAL
                     NPNLIMLGEGWRTYAGDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPA
                     FITGGKRDVNTIFKNLIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKA
                     ENYAEIHRRLRLGNLMVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHL
                     LRDKDGNPFDYPYFIHDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQS
                     TDAFRLKSLQDIKDRVHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKARE
                     FNLGTAFAHLRNAEVLADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTS
                     HESTAEEKPDSTPSKPEHQNEASHPEHQDPAPEARPDSTKPDTKVADAENKPSQATAD
                     SQAEQPAQEAQASSVKEAVRNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGI
                     SLLALLGLGFLLKNKKEN"
     gene            5459..5872
                     /gene="rpsL"
                     /locus_tag="VQT46_000945"
     CDS             5459..5872
                     /gene="rpsL"
                     /locus_tag="VQT46_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET2370990.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            5892..6362
                     /gene="rpsG"
                     /locus_tag="VQT46_000946"
     CDS             5892..6362
                     /gene="rpsG"
                     /locus_tag="VQT46_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET2370991.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            6787..8868
                     /gene="fusA"
                     /locus_tag="VQT46_000947"
     CDS             6787..8868
                     /gene="fusA"
                     /locus_tag="VQT46_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET2370992.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEEIRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            8972..13363
                     /locus_tag="VQT46_000948"
     CDS             8972..13363
                     /locus_tag="VQT46_000948"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET2370993.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFESVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            13465..13728
                     /locus_tag="VQT46_000949"
     CDS             13465..13728
                     /locus_tag="VQT46_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET2370994.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            13721..13999
                     /locus_tag="VQT46_000950"
     CDS             13721..13999
                     /locus_tag="VQT46_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET2370995.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            14020..14172
                     /locus_tag="VQT46_000951"
     CDS             14020..14172
                     /locus_tag="VQT46_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2370996.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            14194..15435
                     /locus_tag="VQT46_000952"
     CDS             14194..15435
                     /locus_tag="VQT46_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET2370997.1"
                     /translation="MVLPNFKENLGKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFKNAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            15445..15675
                     /locus_tag="VQT46_000953"
     CDS             15445..15675
                     /locus_tag="VQT46_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET2370998.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            15898..16620
                     /locus_tag="VQT46_000954"
     CDS             15898..16620
                     /locus_tag="VQT46_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET2370999.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNNGQLAHVLLSPKRHVDKTYQAQVKGIMTQEDVETFIKGIPLKDFTC
                     QPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            16837..18171
                     /gene="pepC"
                     /locus_tag="VQT46_000955"
     CDS             16837..18171
                     /gene="pepC"
                     /locus_tag="VQT46_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET2371000.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALECRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQATVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(18227..19138)
                     /locus_tag="VQT46_000956"
     CDS             complement(18227..19138)
                     /locus_tag="VQT46_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2371001.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(19162..19965)
                     /locus_tag="VQT46_000957"
     CDS             complement(19162..19965)
                     /locus_tag="VQT46_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET2371002.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQT46_000958"
     CDS             complement(19993..20982)
                     /gene="manX"
                     /locus_tag="VQT46_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET2371003.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQT46_000959"
     CDS             complement(21215..22234)
                     /gene="adhP"
                     /locus_tag="VQT46_000959"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET2371004.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
     gene            complement(22573..23385)
                     /locus_tag="VQT46_000960"
     CDS             complement(22573..23385)
                     /locus_tag="VQT46_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2371005.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKRTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKEMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            23575..24993
                     /locus_tag="VQT46_000961"
     CDS             23575..24993
                     /locus_tag="VQT46_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET2371006.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            25046..25753
                     /locus_tag="VQT46_000962"
     CDS             25046..25753
                     /locus_tag="VQT46_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2371007.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            25848..26822
                     /gene="folP"
                     /locus_tag="VQT46_000963"
     CDS             25848..26822
                     /gene="folP"
                     /locus_tag="VQT46_000963"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET2371008.1"
                     /translation="MMKILEGVTDMSSKANHAKTVICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISIDT
                     WKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSSLI
                     FPHFGFGQTFTEKELADFETLPIEDLMVAFFERALARAAEAGITPENILLDPGIGFGL
                     TKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEESGFEVNPETELGFRNRDTAS
                     AHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            26824..28146
                     /locus_tag="VQT46_000964"
     CDS             26824..28146
                     /locus_tag="VQT46_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2371009.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGIPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLEQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            28127..28681
                     /gene="folE"
                     /locus_tag="VQT46_000965"
     CDS             28127..28681
                     /gene="folE"
                     /locus_tag="VQT46_000965"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET2371010.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            28724..29536
                     /gene="folK"
                     /locus_tag="VQT46_000966"
     CDS             28724..29536
                     /gene="folK"
                     /locus_tag="VQT46_000966"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET2371011.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFEFYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIYILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPTLKQPIRNLYDALKK"
     gene            complement(29581..29898)
                     /locus_tag="VQT46_000967"
     CDS             complement(29581..29898)
                     /locus_tag="VQT46_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET2371012.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMYGRETILLPEEN
                     DLF"
BASE COUNT         8527 a         5841 c         7006 g         8700 t
ORIGIN      
        1 ttagaataat ttttcaaatt gaaggacaga gatagacaag gagaatcaca atggtagaat
       61 tgggaatttc aacatttggg gaaataacgg agcttgaagg gactggacaa acttacagtc
      121 atgctgaacg cattcgccag ttggtggcag agattgagct ggctgacaag gttggtttgg
      181 acgtatatgg gattggcgag caccatcggg cggattttgc agtatcagcc ccagagattg
      241 tcctggccgc tggggcagtc aataccaaga aaatccgttt gaccagtgca gtcagcattc
      301 tgtcaagcat ggatccgatt cgtttgttcc aacagtatgc cactatcgat gctttgtcaa
      361 atggacgagc ggagattatg gctggaaggg gctctttcac ggaatctttc cctctgtttg
      421 gttatgactt gaaagactac gactctcttt ttgatgagaa attagacttg cttcagttag
      481 tcaatgaaaa gaccaagtta gactggcaag gtcgattgac tcaaacgatt gctggtaaag
      541 aagtttatcc tcgtccagtt caggacaaat tgcccttgtg gatagctaca ggtggtcatg
      601 tcgaatcaac agtgaagatt gctcaggctg gtctaccgat tgtatatgct attattggtg
      661 gtaatccacg ttattttaaa aagttgattc aggcttatcg tgagattgga agcgaagcgg
      721 tccatgctga caaagacttg aaagtgggag cccattcttg ggggtggatt gcggaagatg
      781 gtgagcaggc ggtgaaagat tatttccatc cgactaagca agtggtggat gctatttcca
      841 aagaccgtcc gcactggcag gaattgcgtt atgagcaata tttggagcag gtagggtcaa
      901 atggcgccat gtttgttggc aatccagatc aggtggccga aaaattgatt cgcatgatag
      961 aggatttagg attggaccgc ttcatgcttc atctaccgct tggttctatg cctcatgacc
     1021 aggttctgag agctattgaa ctcttcggaa cacaagttgc acccaaagta cgagcttatt
     1081 ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt tattaggaca acaaatattg
     1141 tacgaaaatt aatcccccga gctataatgc ttgggggatt tttctatagg agggctagtt
     1201 tagttctctt ttttattttt tagtaagaaa ccgagaccaa ggagcgcaag gaggctgatt
     1261 cctgcaaata ggagtttgtt ttcgttttta attcctgtat ttggaagttc agcttgtcta
     1321 tctggggttg caggtatatt tttcttgcta gagttttcta ccgattcgtt tcgaaccgct
     1381 tcttttacag atgatgcttg tgcttcttgt gctggttgtt cagcttgtga atcagctgta
     1441 gcttggctag gtttattttc cgcatcagct actttggtat ctggtttagt agaatcaggt
     1501 ctagcttctg gagctggatc ttgatgttca gggtgagaag cttcattttg atgttcaggc
     1561 ttggaagggg ttgagtctgg tttctcttct gcagttgact catggctagt tccattttga
     1621 gagactcgaa gaacagtagc tgtaagggca ttcaatttca agcctttttc agtccattca
     1681 agtcctttcg ggttggcaat tccgactgat cctgcttggt tttcatctgc caaaacttcc
     1741 gcatttctta gatgtgcaaa ggcagttccc aaattaaatt cgcgagcttt ttcatccgca
     1801 ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga tttgatagcc aatcactaca
     1861 tcctcttttt ccacaccatt ttggcctggg acagtgatga ggtggacacg gtctttgata
     1921 tcttgaagac tcttaagtcg gaaggcatct gtagattgac gaagggcaat caaacctttc
     1981 atatagtcac ggctcttgac attttcagga taagctttac catctgtagc cttagtccag
     2041 tcaaacttgt tgactgcatc actagaatcg taagagtcat ggatgaagta aggatagtca
     2101 aatgggttgc cgtccttatc acgcaacaag tgagatttgt ttggaacctt atcctctgct
     2161 actggagtct tgtaggctgg gtcacggaat tgtttagtac gtccatattc ctgaccggag
     2221 tggataaatg gagttccttg agctgtcaag accatgagat ttccaagtcg taaacgacgg
     2281 tggatttcag catagttctc agccttgctt gggtcttttt tgatagactg ggcaatgatg
     2341 tcaaagaggg tcaagttatc atgggctgcg atgtattgga tgacatctcc agggctgtca
     2401 gcttcaaagt tagttggttg agcaatgaga tttttaaaga tggtgttgac atcacgcttg
     2461 ccacctgtga taaaggcagg ttgaccttcg tttggataac cagatttgag gttgttacgg
     2521 atgtcatctg aaaagacagc gacagtatcg gtatgtttca tccaatcttg gtcagcagct
     2581 ttagtaggca tgttttcatc accggcatag gttctccaac cttcaccaag catgatgagg
     2641 tttggattga gggcgcgtgc agccttgtaa gcttcttcga tagaagcggc gtcatggtct
     2701 cccatcatat cgaaacggaa gccatccact ttgtaggtat caactaggta tttgatagag
     2761 tcaattagga gccgtttggt catatggtgg gttgtcccca agcgtccacc accaaagcta
     2821 gttcgaggtg tgccatcggc atccataaag tggtagtagt ttggttccaa atcttcaaag
     2881 agatcgactt tggctgtgtg gttataaacg acatctagga tagctcccat accacgtttg
     2941 tggatttcgt tgatgaggtt tttaaattct gcgattcgtt tttctggatt cttaggatcg
     3001 cttgagtaca taccagtcaa ggagaagtag ttttgagggt catatcccca gttgtagttg
     3061 ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt tcaattcatt gacaaagtag
     3121 taagacaaga ctggaaggag ctggatatgg gttacaccca agtctttgag atagtctagt
     3181 ttttcaatga aggcttcaaa agtcccaaat ggtttggtca agtcttttgc aatggcagga
     3241 tctgaagtga aatcacgcac atgagcttcg tagataacgg cgtcttcacg agtcttgaaa
     3301 ttgtgaatct taccataagt caagtcttga ggtccgagtt tagctggatc tacaaaggcg
     3361 gctttagcca ctttatgggc atcgtcaatc ttggaatcgt cgctattcca agcagcaaga
     3421 gatttagcgt aaggatcgag tgcaagaaca gttttacctt gacgctcgat ttggtattga
     3481 taatagtagc cagtgaaatc tgtgattccg agtttgtttg tgctgtctag agtttgtttc
     3541 caagttcctc tttccccttt ttcaagagcg acagttccaa ctactttgtc agggtcattc
     3601 ttgtcgtaga caacaacaga aaccttatca gcacttggtg accaaagggt caaatcaact
     3661 tgttttcctt cttcttttag gtcagctccc agtttgccat catagctgta tgtctcatct
     3721 ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat tgtagctaac agtataagga
     3781 tgttttgtgt cagagaaatc tccgctgtag gtcactttct taccagcttc atcgattgca
     3841 acatcggtaa tagttacctt gtttcctagg tgattagtga tgttggagtg tttgaggata
     3901 tcttcttttt tagcaccgac aagtgttgaa aagctacttt caatgctaga agtgcctacg
     3961 tgttgggctc ctgtcatacg gatatcatgg acatagtatg gatttgtgta aatcgattca
     4021 tcatcgtctt ttaggaaaat ttggctatga tttttcaaat ctgtgaactt ataattttct
     4081 ttacggattt tcacgtcgtc tccttgtttg ctctcatcta gtaataaaaa tccaaattct
     4141 cttgcggctt cattaagagg aatgtcgata tagcggccat atttgcctgt agccgtaaag
     4201 tctgttccgt caggccattg agcgctactt ggatttttca catctcccca gtaccagaga
     4261 gatttcttgt catagttgcc atctgtgcgg tagtagttga cgcgaacagt tcctgcaggc
     4321 tgtggctcgt aagagaaaac cttgtaatct tggtctaacc aagcttcgtt catttttgga
     4381 actagttttt ctacagattt atcgccggtt agattttttc cagctgtatt gttgatgagg
     4441 aagctaattt tcttggcttg ttctcccttt aatttgacat ctaggtaata gccgtagtca
     4501 tctttcttgg catccttgaa ggacaaagct ccgtttggcc agttttcaga tggtttttca
     4561 acatcgtccc aagtccatag tccttgagca tccttgtttt cttcaggaag ttttttgaca
     4621 tggatacgga agtagttatc ttcgatgggc tcttctgcct tagtttcagt tgttactgga
     4681 ctagtagaag tagttggctc acttgaacga tcttgtccag tttgtggtgc tggatcggct
     4741 gggcttgcag caggtttttc ttctgttttc tctagggaag cgtttgcatt tccaggtgaa
     4801 gaaatatcac tttcgttctt accagagcca gctgctgtat cagtaagagg ttgggcaagg
     4861 gtggttgtat ttctgttgtt gggttcgtta gtggttggtg tactttcgtc ggatgagata
     4921 gttggtgtag ccatggcaag caagacaagg cttgcgccga taaggacaga accagttcca
     4981 tttttgaggg aacggatgct gtagaccatt tttttctcag tgtgagatgg tgtttttctc
     5041 ataatgattc tccaatcaat aaatttctat atcagtatag catgtagtaa aacaatatgc
     5101 aagcgttttc tttgatttgt gaaagaaatt cttacttttg agaagttttc cgtactattt
     5161 tatatatcag tataaatgac ggagataaaa atgtcacgta agccaagccg tgttattagg
     5221 aagatgatgt gttctcagct atttttattc agaaattgat ctctaacatt accaataaaa
     5281 aagaaaaata tcttgacaag caagggaaaa ttttgttaca ataatagacg gtacttttta
     5341 cttttggtct ctcaagagtg tacagggacg tgctgacaaa tgttgcaaaa gtacacacag
     5401 atgatatctg tcaccaagtg tatcatcacc aaaaataaaa aaacacagga gaatgtagat
     5461 gcctacaatt aaccaattgg ttcgcaaacc gcgtaaatca aaagtagaaa aatctaaatc
     5521 accagctttg aacgttggtt acaatagtca taaaaaagtt caaacaaacg tttcttcacc
     5581 acaaaaacgt ggtgttgcaa ctcgtgttgg aacaatgaca cctaaaaaac ctaactcagc
     5641 ccttcgtaaa ttcgctcgtg tacgtttgag caaccttatc gaagttactg cctacatccc
     5701 aggtatcgga cacaacttgc aagagcacag cgtggtgctt cttcgcggtg gacgtgtaaa
     5761 agaccttcca ggggtacgtt accatatcgt ccgtggtgca cttgatactg caggtgttaa
     5821 cgatcgtaaa caaggccgtt ctaaatacgg tactaaacgt ccaaaagcat aaggaaaggg
     5881 gataaagaga aatgagtcgt aaaaatagag ctccaaaacg tgacgtattg ccagatccgc
     5941 tatacaattc acaactagtt actcgtctta tcaaccgcgt tatgcttgat ggtaaacgtg
     6001 gtactgctgc ttcaatcgtt tacggtgctt ttgagcaaat caaagaagct actggcaacg
     6061 atgcacttga agtatttgaa acagctatgg aaaacatcat gcctgtactt gaagtacgtg
     6121 cacgtcgtgt tggtggttct aactaccaag tcccagttga agttcgtcca gaacgtcgta
     6181 caacacttgg acttcgttgg ttggtaacaa tcgctcgtct tcgtggtgaa cacacaatgc
     6241 aagaccgtct tgcaaaagaa atcttggatg ctgctaacaa cactggtgca gcagttaaga
     6301 aacgtgaaga tactcaccgt atggctgaag ctaaccgtgc attcgcacac ttccgttggt
     6361 aagataggat gcgaaagcgt taagaaagtc ccagagaaaa tagggaatcg aagcaggttg
     6421 cggttgcaac caatgagatt catctttttc tccagacttt tagcttgagc tcaactaaat
     6481 catgatgcta ggaacggtaa ggatgcaagg taaaaatagg aaactgacgc agtattcgac
     6541 gaatacaagg agttttatct ttttcacgca gcatcccgtt ccagctcaca tcggctaact
     6601 aactttagcc cgggttcaaa ttagctaaat cgattagtat tagctataac tcagcttacc
     6661 atctcgtaag ttgaaaccaa caatagcatg aaaacattga gaacgggtag gtcctgccta
     6721 tccgttttta ttaaaatcgt gttataatag aatagaaatc aaaaataaat aggagaaaca
     6781 aacctcatgg cacgcgaatt ttcacttgaa aaaactcgta atatcggtat catggctcac
     6841 gtcgatgccg gtaaaacaac aactactgag cgtattcttt actacactgg taaaatccac
     6901 aaaatcggtg aaactcacga aggtgcgtca caaatggact ggatggagca agagcaagaa
     6961 cgtggtatca cgatcacatc tgctgcgacg acagctcaat ggaacaacca ccgcgtaaac
     7021 atcatcgaca caccaggaca cgtggacttc acaatcgaag tacaacgttc tcttcgtgta
     7081 ttggatggtg cggttaccgt tcttgactca caatcaggtg ttgagcctca aactgaaaca
     7141 gtttggcgtc aagcaactga gtacggagtt ccacgtatcg tatttgccaa caaaatggac
     7201 aaaatcggtg ctgacttcct ttactctgta agcacacttc acgatcgtct tcaagcaaat
     7261 gcacacccaa tccaattgcc aatcggttct gaagatgact tccgtggtat cattgacttg
     7321 atcaagatga aagctgaaat ctatactaac gaccttggta cggatatcct tgaagaagac
     7381 atcccagctg aataccttga ccaagctcaa gaataccgtg aaaaattgat tgaagcagtt
     7441 gctgaaactg acgaagaatt gatgatgaaa tacctcgaag gtgaagaaat cactaacgaa
     7501 gaattgaaag ctggtatccg taaagcgact atcaacgttg aattcttccc agtattgtgt
     7561 ggttcagcct tcaaaaacaa aggtgttcaa ttgatgcttg atgcggttat cgactacctt
     7621 ccaagcccac ttgacatccc agcaatcaaa ggtattaacc cagatacaga cgctgaagaa
     7681 attcgtccag catctgacga agagccattt gcagctcttg ccttcaagat catgactgac
     7741 ccattcgtag gtcgtttgac attcttccgt gtttactcag gtgttcttca atcaggttca
     7801 tacgtattga atacttctaa aggtaaacgt gaacgtatcg gacgtatcct tcaaatgcac
     7861 gctaacagcc gtcaagaaat cgacactgtt tactcaggtg atatcgctgc tgccgttggt
     7921 ttgaaagata ctacaactgg tgactcattg acagatgaaa aagctaaaat catccttgag
     7981 tcaatcaacg ttccagaacc agttatccaa ttgatggttg agccaaaatc taaagctgac
     8041 caagacaaga tgggtatcgc ccttcaaaaa ttggctgaag aagatccaac attccgcgtt
     8101 gaaacaaacg ttgaaactgg tgaaacagtt atctcaggta tgggtgaact tcaccttgac
     8161 gtccttgttg atcgtatgcg tcgtgagttc aaagttgaag cgaacgtagg tgctcctcaa
     8221 gtatcttacc gtgaaacatt ccgcgcttct actcaagcac gtggattctt caaacgtcag
     8281 tctggtggta aaggtcaatt cggtgatgta tggattgaat ttactccaaa cgaagaaggt
     8341 aaaggattcg aattcgaaaa cgcaatcgtc ggtggtgtgg ttcctcgtga atttatccca
     8401 gcggttgaaa aaggtttggt agaatctatg gctaacggtg ttcttgcagg ttacccaatg
     8461 gttgacgtta aagctaagct ttatgatggt tcatatcacg atgtcgactc atctgaaact
     8521 gccttcaaga ttgcggcttc actttccctt aaagaagctg ctaaatcagc acaaccagct
     8581 atccttgaac caatgatgct tgtaacaatc actgttccag aagaaaacct tggtgatgtt
     8641 atgggtcacg taactgctcg tcgtggacgt gtagatggta tggaagcaca cggtaacagc
     8701 caaatcgttc gtgcttacgt tccacttgct gaaatgttcg gttacgcaac agttcttcgt
     8761 tctgcatctc aaggacgtgg tacattcatg atggtatttg accactacga agatgtacct
     8821 aagtcagtac aagaagaaat tattaagaaa aataaaggtg aagactaatc cgtcctcact
     8881 ctagaaggaa gtcacttagt ggcttccttt tgtctttaga aaatacctct aaatatggta
     8941 aaatagtaga agaataatgt gaggaaaatg aatgtcaaat agttttgaaa ttttgatgaa
     9001 tcaattgggg atgcctgctg aaatgagaca ggctcctgct ttagcacagg ccaatattga
     9061 gcgagttgtg gttcataaaa ttagtaaggt atgggagttt catttcgtat tttctaatat
     9121 tttaccgatt gaaatctttt tagaattaaa gaaaggtttg agcgaagaat tttctaagac
     9181 aggcaataaa gctgtttttg aaattaaggc tcggtctcaa gaattttcaa atcagctctt
     9241 gcagtcctac tatagggagg ctttctctga aggtccatgt gctagtcaag gttttaagtc
     9301 cctttatcaa aatttgcaag ttcgtgctga gggtaatcag ctatttattg aaggatctga
     9361 agcgattgat aaggaacatt ttaagaagaa tcatcttcct aatttagcca aacaacttga
     9421 aaagtttggt tttccaactt ttaactgtca agtcgagaag aatgatgtcc tgacccaaga
     9481 gcaggaagag gcctttcatg ctgaaaatga gcagattgtt caagctgcca atgaggaagc
     9541 gctccgtgct atggaacaac tggagcagat ggcacctcct ccagcggaag agaaaccagc
     9601 ctttgatttt caagcgaaaa aagctgcagc taaacccaag ctggataagg cggagattac
     9661 tcctatgatc gaagtgacga cagaggaaaa tcgtctggta tttgaagggg ttgtttttga
     9721 tgtggagcaa aaagtgacta gaacaggtcg tgttttaatc aactttaaaa tgacggacta
     9781 tacttcaagt ttttctatgc aaaagtgggt taaaaacgag gaagaggccc agaagtttga
     9841 cctcatcaag aagaattctt ggctccgagt tcgagggaat gtggagatga ataacttcac
     9901 acgcgatttg actatgaacg tacaggatct gcaggaagtt gttcactatg agcggaagga
     9961 tttgatgcca gaaggtgagc gtcgggttga gtttcatgct catactaaca tgtcgactat
    10021 ggatgctttg ccagaggtcg aagagattgt tgcaacagct gctaagtggg gacacaaggc
    10081 ggttgctatc acggaccatg ggaatgtcca gtcctttcca catggctata aggcggctaa
    10141 gaaagcggga atccagctga tctatgggat ggaagccaat atcgtggagg accgtgtccc
    10201 tatcgtctat aacgaagtgg agatggactt gtcagaagca acctacgtgg tctttgacgt
    10261 ggaaacgacg ggactttcag ctatctataa tgacttgatt caggttgcgg cttctaagat
    10321 gtacaagggg aatgttattg ctgaatttga tgaatttatc aatcctgggc atcccttgtc
    10381 agcctttact acagagttaa ctggaattac agatgatcat gtcaaaaatg ccaaaccact
    10441 agaacaagtt ttgcaagaat tccaagaatt ttgcaaggat acggtcctag ttgcccacaa
    10501 tgctaccttt gacgttggct ttatgaatgc taattatgag cggcatgatc ttccaaagat
    10561 tagtcagcca gttattgata cgctggagtt tgctagaaac ctctatcctg agtataaacg
    10621 ccatggtttg gggcctttga ccaagcgttt tggtgtggcc ttggaacatc accacatggc
    10681 caactacgat gcggaagcga ctggtcgtct gcttttcatc tttatcaaag aggtagcaga
    10741 aaaacatggt gtgaccgatt tagctagact caacattgat ctaatcagtc cagattctta
    10801 caaaaaagct cggatcaagc atgcgaccat ctatgtcaag aatcaggtag gtctaaaaaa
    10861 tatctttaag ctggtttcct tgtctaatac caagtatttt gaaggagtgc cacggattcc
    10921 gagaacggtt ctagatgccc atcgagaggg cttgatttta ggttcagcct gttcagaggg
    10981 tgaagttttt gacgtggtcg tttctcaagg tgtggatgcg gcggttgagg tggccaagta
    11041 ttatgatttt atcgaggtca tgccaccggc tatctatgca cccttgattg ccaaagagca
    11101 ggtcaaggat atggaggaac tccagaccat tatcaagagt ttgatagagg ttggagaccg
    11161 ccttggcaag cctgttctgg ctacgggaaa tgttcactat atcgaaccgg aagaagagat
    11221 ttatcgtgaa attatcgtcc gtagtttggg acagggtgcg atgattaatc gaactatcgg
    11281 tcatggtgaa catgcccaac cagcaccact tccaaaggct cattttcgaa cgactaatga
    11341 gatgttggat gaatttgcct ttttgggaga ggaactggct cgtaaactgg ttattgaaaa
    11401 caccaatgcc ttggcagaaa tatttgaatc cgttgaagtc gttaagggtg acttgtatac
    11461 gcctttcatc gacaaggctg aagaaacagt tgctgagttg acctataaga aagcttttga
    11521 gatttatgga aatccgctgc cagatattgt tgatttgcgg attgaaaaag aattaacatc
    11581 catactgggg aatggatttg ctgtgattta tctggcatcg cagatgctgg tgcaacgttc
    11641 taatgaacgg ggttatttgg ttggttctcg tgggtctgtc ggatctagtt tcgttgcgac
    11701 catgattggg attacggagg tcaatcctct ctctcctcac tatgtctgtg gtcagtgtca
    11761 gtacagtgag tttatcacag atggttcgta cggttcagga tttgatatgc cccataagga
    11821 ctgtccaaac tgtggtcaca aactcagtaa aaacggacag gatattccgt ttgagacctt
    11881 ccttggtttt gatggggata aggttcctga tattgacttg aacttctcgg gagaagatca
    11941 gcctagcgcc cacttggatg tgcgtgatat ctttggtgaa gaatatgcct tccgtgcggg
    12001 aacggttggt acggtagctg ccaagactgc ctatggattt gtcaagggtt acgagcgaga
    12061 ttatggcaag ttttatcgtg atgcagaagt agaacgcctc gctcaaggag cggcgggtgt
    12121 caagcggaca acaggccaac acccgggggg aatcgttgtt attccgaact acatggatgt
    12181 ctacgatttt acgcctgtcc agtatccagc agatgatgtc acggctgaat ggcagaccac
    12241 tcactttaac ttccacgata tcgatgagaa cgtcctcaaa ctcgatgtac tgggacatga
    12301 tgatccgacc atgattcgaa aacttcagga tttgtctggt attgacccta ataaaattcc
    12361 tatggatgac gaaggcgtga tggcactctt ttctgggact gatgtactag gggtaacacc
    12421 tgaacaaatt ggaacgccta cgggtatgtt ggggattcca gagtttggaa caaatttcgt
    12481 acgtggaatg gtagacgaaa cccatccgac aacctttgcg gaattgcttc agctgtctgg
    12541 tctgtcccac ggtactgacg tttggttggg gaatgctcag gatctgatta agcaaggaat
    12601 agcggaccta tcgactgtta tcggttgtcg ggacgacatc atggtttacc tcatgcatgc
    12661 gggtctggaa cctaagatgg cctttaccat tatggaacgg gtacgtaagg gtttgtggct
    12721 aaagatttca gaagaggaga gaaatggcta tatcgaagcc atgaaggcta ataaggtgcc
    12781 agagtggtat atcgaatcct gtgggaaaat taagtacatg ttccctaagg cccatgcggc
    12841 agcctacgtt atgatggcct tgcgtgtagc ttacttcaag gttcaccatc ctatttatta
    12901 ctactgtgct tacttctcca ttcgtgctaa ggcttttgat atcaagacca tgggtgcggg
    12961 cttggaggtc atcaagcgca gaatggaaga aatctctgaa aaacggaaga acaatgaagc
    13021 ctctaatgtg gaaatcgatc tctatacaac tcttgagatt gtcaatgaga tgtgggaacg
    13081 aggtttcaag tttggtaaat tagatctcta ccgtagtcag gcgacagagt tcctcatcga
    13141 cggggatacc cttatcccac catttgtagc aatggatggt ctgggagaga acgttgccaa
    13201 gcaactggtg cgggcgcgtg aagagggaga attcctctct aaaacagaac tacgcaagcg
    13261 tggtggactc tcatcaacct tggttgaaaa gatggatgag atgggtattc ttggaaatat
    13321 gccagaggat aaccagttga gtttgtttga tgagttgttt taaaaaattg cttaataatc
    13381 tattaaaaga ggctaacgta tatccaatag atttacatta gctttctttt ttgttaaaat
    13441 agtctatgga aagagggtga gagtatgtca aagatgagta taagcatccg tctggatagt
    13501 gaggttaagg agcaggccca acaggtgttt agtaatctgg gaatggatat gacaacagct
    13561 attaatattt tccttcgtca ggcaattcaa tatcagggat taccttttga tgttagacta
    13621 gacgaaaatc ggaagttgct ccaagcgtta acggatttag accaaaatcg taatatgagc
    13681 cagtcttttg aatcagtctc agatttgatg gaggacttac gtgcttaaga ttcgttatca
    13741 taaacagttt aaaaaagatt ttaagttggc tatgaagcgt ggtttgaagg cagaattatt
    13801 agaagaagtt ttgaattttc tggttcaaga aaaagaacat cctgccagat atcgtgatca
    13861 ttcattgacg gcatccaagc attttcaagg agttcgtgaa tgccataccc agccagattg
    13921 gcttttggtt tataaagtag acaagtcgga attgatttta aatttgctga ggacaggcag
    13981 tcacagtgat ttattttaat ctattttaag ggggttctca tgaaactaag aatatttgcg
    14041 gaagataagc cggctaagaa ggtatttgaa tatcaattag aacttgctga tcgtacaatt
    14101 cttctatcga cagcactctt gtcaggtgct attgctttag caggaatctt ttctgctttg
    14161 aaagaaaaat aaaaatagaa aagagaaaac agaatggttt taccaaattt taaagaaaat
    14221 ctaggaaaat atgcgaaatt gttggttgcg aacggaatta acgtgcaacc tggtcacact
    14281 ttggctctct ctattgatgt ggagcaacgt gaattggcac atctaatcgt gaaagaagct
    14341 tatgccttgg gtgcgcatga ggtcatcgtt cagtggacag atgatgtgat taaccgtgag
    14401 aaattcctcc atgccccgat ggagcgtttg gacaatgtgc cagaatacaa gattgctgag
    14461 atgaactatc ttttggagaa caaggctagc cgtcttgggg ttcgttcatc tgatccaggt
    14521 gccttgaacg gagtggacgc tgacaagctt tcagcttctg ctaaagctat gggacttgcc
    14581 atgaagccta tgcgtatcgc aactcaatct aacaaggtta gctggactgt agcagccgct
    14641 gctggacttg agtgggctaa gaaagtcttc ccaaatgctg cgagcgacga agaagcagtt
    14701 gatttccttt gggatcaaat cttcaaaact tgtcgtgtct acgaagcaga tcctgttaag
    14761 gcttgggagg aacatgcagc cattctcaag agcaaggccg atatgcttaa taaggagcaa
    14821 ttttcagccc ttcactacac agcgccagga acagatttaa cacttggttt gccaaagaac
    14881 cacgtttggg aatcagctgg tgctgtcaat gcacagggcg aagaattctt gccaaatatg
    14941 ccgacagaag aggtcttcac agcgcctgac ttccgtcgtg cagatggtta tgtcacttct
    15001 acaaaaccgc ttagctacaa cggaaatatc attgaaggca ttaaggtgac ctttaaggat
    15061 ggacaaatcg tagatatcac tgctgagaag ggtgatcagg ttatgaaaga ccttgtcttt
    15121 aaaaatgcgg gtgcgcgtgc cttgggtgaa tgtgccttgg taccagatcc aagtccaatt
    15181 tctcagtcag gcattacctt ttttaacacc cttttcgatg aaaatgcgtc aaaccacttg
    15241 gctatcggtg cagcctatgc gactagcgtt gttgatggag cggagatgag cgaagaggag
    15301 cttgaagctg cagggcttaa ccgttcagat gttcacgtag actttatgat tggttctaac
    15361 caaatggata tcgatggtat tcgtgaggat ggaacgcggg tacctctttt ccgtaatggg
    15421 aattgggcaa attaaggaga taatatgtta ggaagtatgt tcgttggtct cctagtggga
    15481 tttttagcag gtgctatgac caatcgtgga gagcgaatgg gatgttttgg aaaaatgttt
    15541 ctcggttgga tcggagcctt tctaggtcac ttgctctttg gaacttgggg gccagtttta
    15601 tcaggaacag ctattatccc agcgatttta ggagccatga ttgttttagc tattttttgg
    15661 agacgaggaa gttaatttcc taaatctgat actcaatgaa aatcaaagag caaactagga
    15721 aactagccgc aggttgctca aagcactgct ttgaggttgc agatagaact gacgaagtca
    15781 gtaacatata tacggcaagg cgacgttgac gcggtttgaa gagatttttg aagagtatga
    15841 aacgaaaagg aggttggtca ttgtactagc ctccttttga tatgatataa tagttctatg
    15901 agattagata aatttttagt tgcctgtgcg gtgggaagtc ggactgaggt caaaaacttg
    15961 ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa aatcagctaa attgcagatt
    16021 gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt tggagtatga agagtttgtc
    16081 tactacatga tgaacaagcc caaaggagtt atctcagcga ctgaggatcc caagcacaga
    16141 accgttctgg acttgttgga tgacttggcg cggagtaagg aagtttttcc agtaggacgc
    16201 ttggatattg acacgcatgg tcttttgctc ttgaccaata atggtcagct ggctcatgtt
    16261 cttctttcgc ccaagcgtca tgtggacaag acttatcagg ctcaggtcaa gggaattatg
    16321 acccaagaag atgtggagac atttatcaag ggcattccgc tcaaagactt tacctgtcag
    16381 cccgctagac tggagattct ttccacagat gcagaaaaga atcagagcca aatccgtgtg
    16441 accattgcag aagggaagtt tcatcagatc aagcgtatgg tgggctactg tggcaaggaa
    16501 gtggtggact tgcaacgatt gactatggga actttagtat tagatgagaa cctggaacga
    16561 ggggaatggc gtcgcttgac caaggaagaa ttagaaattc tccgcgctaa tattatttaa
    16621 tttagtttaa tactcaatga aaatcaaaga gcaaactagg aaactagccg caggctgtac
    16681 ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaattcg
    16741 aaaaaggtga gggacaatgt cctcgccttt tatgtttttt agttgcttcc tttgtgaaaa
    16801 gagttataat agactgtaga ataaaaggag gaatctatga acgcgattca agaatcattt
    16861 actgataaac tatttgccaa ctatgaagca aatgtaaaat accaagcgat tgaaaatgct
    16921 gccagccaca acggaatttt tgcagctctg gaatgtcgcc aaagccatgt agacaacaca
    16981 cctgttttct cattggattt aaccaaggac aaggtcacta accagaaagc gtctggtcgt
    17041 tgctggatgt ttgcggctct caacaccttc cgccacaaac tcatctcgca atacaaattg
    17101 gagaactttg agttgtcaca agcccacact ttcttctggg ataagtatga gaaatcaaac
    17161 tggttcttgg agcaagtcat tgcgacttca gaccaagaat tgactagccg caaggttagc
    17221 ttcttactcc aaacacctca acaagatggc ggtcaatggg atatggtcgt ttccctcttt
    17281 gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt ctgtttcatc tagcagcagt
    17341 cgtgagctaa atgcgatcct taataaattg cttcgtcaag atgctcaaat cttgcgtgat
    17401 ttgcttgttt ctggtgcaga tcaagcgact gttcaagcta agaaagaaga cctcttgcaa
    17461 gaaatcttta actttcttgc tatgtcatta ggacttccac cacgcaagtt tgactttgct
    17521 tatcgcgata aagataacaa ctataaaagt gaaaaaggaa tcacaccaca agagttttac
    17581 aagaaatatg tcaatcttcc tttagaagac tacgtttctg ttatcaatgc tccaactgct
    17641 gataaacctt acggaaaatc ttacacagtt gagatgttgg ggaatgtggt tggtagccgt
    17701 gcagttcgct acatcaacgt tccaatggag cgcttgaaag aattggcgat tgcccaaatg
    17761 caagcaggtg agactgtttg gtttggttct gatgtcggcc agctcagcaa ccgtaaggct
    17821 ggcatccttg cgacagatgt ttatgacttt gaatcaagca tggacattaa acttactcaa
    17881 gacaaggctg gacgtttgga ctatagcgaa agcttgatga cccacgccat ggtcttgaca
    17941 ggtgttgact tggacgaaaa tggtaaatca accaagtgga aggttgaaaa ctcatgggga
    18001 gacaaggtcg gtacagatgg ttactttgtt gcctcagacg cttggatgga cgaatacaca
    18061 taccaaatcg ttgttcgtaa ggaattgctg acagcagaag aacaagctgc ctatggagca
    18121 gaaccaatcg tacttgcacc atgggatcca atgggagcct tggctgaata aaagcataga
    18181 aaaaaggaat cagattttag aacctggttc ctttttagtt gcttgattac atgatgtgaa
    18241 gaacatgtgc cacaataccc actgcgaaga gggcaaggat aatagtgatt ggagatactt
    18301 ttttcttaag taagtacatg caaagtaaag taaggagtag tcctgataat ccaggaatca
    18361 acatatccaa gttttgttgg aaagtagtaa ctttttcagg agtttgagac aatccttgtc
    18421 ctacttgtgc gaatgcttct tggatacctt tagacccttc tggcaattta tcccaatgga
    18481 tataagcctt ttcatctagt tgaactttag aaacatcgaa agcaaattta atatttaccc
    18541 agcgttgaac aaggacagca agaatgaaca tcccaaggat agaagctcct ttagtgatat
    18601 cttgaaggat accaccagac atatctttag tgatttctga tccagccttg tatccaatct
    18661 cttgaacata ccacaagaat gacatacgaa tcaagttcca tgcaacaaag aagaggagtg
    18721 gccccaagat attgccagta agggcaagtg aagcaccgag agatccaagg attgggcgta
    18781 ctgtaaacca gaatactggg tcaccgatac cagcaagagg tcccatcata ccgattttaa
    18841 ccccttggat agcagcgtca tcgatttcca caccgttagc acgttcttct tcaagcgcaa
    18901 gagtaacccc catgactgga gcagctacgt atggatgagt gttgaagaac tcaaggtgac
    18961 gctcaagagc agcgatttga tcttcttttt tagtatagag ttttttgata gctggaatga
    19021 gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt ccaagaccct tgtaagaagg
    19081 ttgaacgcca ccaaactttt ttacgatctg atttagttaa ttgaagtttt tcagtcatga
    19141 tgttttcagt cctttcttat cttagtagtc ttctaggata tcgccgattg ggtcgttaga
    19201 agttgcggct cctccgccac catttccacc agttttagaa aggtgaaggt agataagagc
    19261 gatagcaaca ccgatagcac cgaatccgat tagagtaata tctgacacag cagcaagaac
    19321 gaaaccaaga gcgaagaatg gccatacttc acgagttgcc atcatgttga taaccatggc
    19381 gtaaccaacg gcaacgacca taccaccacc gatagccata ccatctttga gccagtctgg
    19441 catggcacta aggatacttt gtacagtttc agttggtacc ataaggagaa gagctgcagg
    19501 aagcgcgata cgaagtcctt ggaaaagtag cgcaatgaaa tgagcacgct ccacagcgcc
    19561 gaagtcacct tttttagcgg cagcatcagc agtgtgaacc aatccaactg aaattgtacg
    19621 aacaatcata gttaagaata gaccagctac ggcaagaggg atagcaaccg cttgggcaac
    19681 accgatacca gtcttggtaa agtcaccacc aagaaccatg ataatggcag cagcgacaga
    19741 agcaagtgca gcatcaggag cgatagcagc accgatattt gaccaaccaa gggcaatcat
    19801 ttgaagcgat ccaccgagga taatccctgc ttccaagtga cctgttacaa gcccaataag
    19861 ggtacaggct acaagtggtt ggtgaaattg gaactggtcg aggatgcctt caagacctgc
    19921 aaagaaggct acaacgacta ctaaaaccat agaaataata gacatgttta aaatcctttc
    19981 ataaataatg gcttatttga cattggcttt gttaatcaag tcaaacaaat cttttttaga
    20041 atcatttggt actttacgga catcaaattc aacacccaag tcacgcattt tttcaaatgt
    20101 agcaacatct tctttgtcca tagacaaaac ggtattgacc aatgttttac ctgttgagtg
    20161 agccatagaa ccaacgttaa gagtcttgat tggcacgccg ccttcgatgg cacgaagggc
    20221 atcttgaggt gtttcaaaca agataagggc atgtgtttct ccaaaacgtg ggtcttttga
    20281 aatctcaatc agtttttgaa ttggaaccac gttagccttg acattacctg gagctgcttg
    20341 tttaatcaat tctttacgaa ggtcgtcttt agccacgtta tctgaagcaa cgatgatacg
    20401 atttgctttt gaatctggag tccaagcagt tgcaacctga ccgtgaagta gacgtgtgtc
    20461 aagacgggca agattgattt tcaatttacc gtctccgata acagttcctt ctgggatagc
    20521 agtttgggca actggagcag ctgcagcgct tgcaacttct tcaactggat ttagctcttc
    20581 tggaagagct ttgatgccat ctttggcttc tttaatgata ttagcagcga ctttttctac
    20641 acctgcagca gcgtccatga ggcgctctgt gtaggcttga atcaacatcg gtaagttaag
    20701 tcctgtgatg atggcaaact tacgctcagg attttctccc atcacgcgac tagcttggtt
    20761 aaatggagaa ccactccaaa ggtcagccaa aactagaacc tcatcttctg cgtcaaatgc
    20821 agcaacagcg ttattaaact tagcgtatag atcatcagga ccttcatttg gcataaaggt
    20881 cacaacttga accttttctt gttcaccaaa gatcatagat cctgactgat gaatacccgc
    20941 agcaaattcg ccgtggctcg caataatgat tccgatactc attattgtca ttcctccttt
    21001 tttgttttag ttttcattta agaaaacttt aagactgttt aagtataaac cgttttcata
    21061 aaaaaagcaa ctatttatca taaaaaatta aaaaattttt atttttgtat gttgatatgt
    21121 tgagtttttg aggagtaatc ttgaattctt atttaaaatt taatataaaa aagttggaag
    21181 aagcttccaa cttttaaaat aggtttctat taaattagtg ggtgaagtcg agtaccatac
    21241 gtccttggat ttggcctttt tccatttcgt cgaaaatggc aacagcatct tctactggac
    21301 gtttttgaac aactgggact accagacctt ctgcaccaaa ttggaaggct tcttctaagt
    21361 ctttacgagt tccgacaaga gaaccgatga cttggattcc atcgaggact gttttaacga
    21421 tgctgagttc catcatttca gaaggaagac caacagcgac gacgcgacca ccagcacgaa
    21481 tggagtcaac agcctggttg aaggcaactt tagacacagc agttacgaca gctgaatgag
    21541 ctcctccatc agttttttct ttaatgagtc cagctacatc ttcaacttcg aggccgttaa
    21601 tcacaatgtc agcgcctact tcttttgcaa gggtaagttt gtcattgttg atatcgactg
    21661 cgataacatg agcattgaat acttttttag cgtattgaac agcgaggtta ccaagtccac
    21721 cagcaccgta aagaacaacc cattggcctg gttcaacttt tgcttctttg atagctttat
    21781 aggttgttac tccagcacat gtgatagaag aagcttgggc tggatcaagt ccgtcaggaa
    21841 ctttgacagc atagtcagca gttacgatac attgttcagc cataccaccg tctactgagt
    21901 agccagcatt tttcactgta cggcaaaggg tttcgcgacc agttgtacag tattcgcaag
    21961 tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc accgacttta aggcttttca
    22021 catctggagc aatctcttta acgataccga taccttcgtg cccaagaaca cgtcctggga
    22081 cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg gcaaacgcca cagtattcaa
    22141 cttctacaag tgcttcccca gtttcaagtg gacggagtac tttttcttca atagcaacac
    22201 cagtgctttc tggatttaca acaacagctt tcatagctat cctccttgat attgaccgag
    22261 aacagggaca acgggactgg attgattttt tgtcaacaga gtcgagtgtg acgagctctc
    22321 ttgtatttat atgtgaagta tatcacaaaa ggaagccttt tccaaggttt tggagacaaa
    22381 aagtagaaca atcgattaac tggttgatga gactgtgaaa agagcacaaa gaccagcttg
    22441 caagctggtc atactcttcg aaaatctctt caaaccacgt cagcttcatc tacaacctca
    22501 aagcagtgct ttgagcaacc tacggctagc ttcctagttt gctctttgat tctcattgag
    22561 tatcagtata ggttataaga ataagtcttg tagggttttg gcaaccccat cttggtcgtt
    22621 ggtaagggaa atttgctcat ctgcataagg gagtagctct ggattggcat ttttcatggc
    22681 ataacccttc ccagcaaaag cgagcatttc ggtatcattg tgttcatctc caaaggcaat
    22741 caaatctttt ttgtcacgat tcattatctt gagcaagtag tccaaagcaa aggccttgtt
    22801 gacacctttt ggggtacatt caaggatatt gagcggacct ccccaggtat tgatagaaag
    22861 ttgatgctgg tagaaggcgt tcatttcttt tgccaaggca tatttgtcac tggctctggt
    22921 ctgcaagagg atacagttag ggtccttggt caccaattca ggctggaatt gatcttcagg
    22981 ctggaaagct tctacaccaa atagtttggg attggcaatt tcttcattgg gatttgtaat
    23041 gtagaatttt ttacgatatt ctccagcgat aaaatcggct tgaatgtcct ctgaacgttg
    23101 aaccatatct agcagatatt ttttgtctac agtcaaacac ttttcaaaat cccaaacttg
    23161 gtctggtaaa tgagtaaggg atccgttgaa gttaatcata ggagtgtcta agcccagttc
    23221 acggtaaaaa tcttttgaca tacggtaagg gcgacctgtc gtaataataa cctgatggcc
    23281 tttttcagca acttttttga tggttctttt ggtaaagtca gaaatttgac tgtctgagtt
    23341 gagcagggtt ccatccaggt caactgcaat aatttttttc gtcatatgga cctttctagt
    23401 gtgttttcag ataagatgtc ttctattata acagaaagca ggcagaaaag cagattccaa
    23461 acaaaaaatg aaattggatt aatttcttaa acaaatcaaa caaagacatt gaaaaagtga
    23521 atgataaatg atataattct attattgttc gtaaaaatta aaaggagatt gatgatggac
    23581 aaattattta aactaaaaga gaacggtaca gacgttcgta cagaggttct cgctggttta
    23641 acaactttct ttgcaatgag ctatattctc tttgtaaacc cacaaatact ttcacaaaca
    23701 ggaatgcctg ctcagggcgt cttcctagcg acgattattg gtgcagtagc gggtaccttg
    23761 atgatggctt tttatgctaa cttaccttat gcccaagcac caggtatggg actcaatgcc
    23821 ttctttacct ttacagttgt attcgggctt ggttattctt ggcaagaagc cctagctatg
    23881 gtcttcatct gtgggattat ttcattgatt attaccttga caaatgttcg taaaatgatc
    23941 attgaatcga ttcccaatgc tcttcgctca gctatttcag ctggtatcgg tgtcttcctt
    24001 gcctatgtag ggattaagaa tgctggactt ttgaaattca cgattgatcc aggcaactat
    24061 actgttgtag gagaaggggc tgacaaagct caagcaacga ttgcagcaaa ctcttcagca
    24121 gttccaggat tggtcagctt taataatcca gctgttttag tggctcttgc aggacttgcc
    24181 attactatct tctttgtcat caaagggatt aaagggggaa ttattctctc tatcttgaca
    24241 acaactgttc ttgctattgc agttggtttg gttgatttgt ctagtatcga ttttgctaat
    24301 aaccatgttg gtgcagcttt tgaagatttg aagacaatct ttggtgcagc tcttggttca
    24361 gaaggtttgg gagctttggt ttcagataca gctcgcttgc ctgaaactct gatggccatt
    24421 cttgccttct cattgacaga tatttttgac acaattggta ccttgatcgg tacaggtgaa
    24481 aaagttggta ttgtagcgac aaatggtgaa aatcaccaat cagccaaatt ggataaggct
    24541 ctttactctg atttgattgg aacgacagtc ggtgccattg caggtacttc aaacgtaacg
    24601 acttatgttg agtctgctgc tggtatcggt gcaggtggac gtactggttt gacagccttg
    24661 gttgtagcta tctgttttgc gatttcaagc ttctttagcc cacttctagc gatcgtacca
    24721 acagcggcta cagctccaat cttgattatc gttgggatta tgatgcttgg tagcttgaaa
    24781 aatatccatt gggatgatat gtctgaagca gttcctgcct tcttcacatc tatctttatg
    24841 ggattcagct actctatcac tcaagggatt gcagttggtt tcttgactta cactttgact
    24901 aagcttgtca aaggtcaagt taaagatgtt catgccatga tttggatttt ggatgccttg
    24961 tttatcctta actacatcag catggcctta taatagaatg acccaggggg atttcccccc
    25021 ttttttaata caaaggagat aggtgatgaa agagaaaaat atgtggaaag aattgttgaa
    25081 tcgtgcaggc tggattttgg tctttttact tgccgtcctt ttatatcagg ttcccctagt
    25141 ggttacctct attttgactt taaaagaagt agccctgcta cagtcagggc tgatagttac
    25201 tggcctttca attgtggttc tggctctatt tattatggga gctcgtaaaa ccaagttagc
    25261 tagttttaat ttttcttttt ttagagctaa agatttggca cgtttgggct tgagttattt
    25321 agttattgtc gggtcaaata tacttggttc tatcttgttg caactgtcaa atgagacgac
    25381 aacagctaac cagtctcaga ttaacgatat ggttcagaat agttctctga tttctagctt
    25441 cttcttgcta gccttgcttg ctccaatttg tgaggaaatc ttgtgccgtg ggattgttcc
    25501 taaaaagatt ttccgaggca aggagaactt gggatttgta gtcggtacga ttgtgtttgc
    25561 tttattgcat caaccaagta atttaccttc tttattgatt tatggaggta tgtcgacagt
    25621 tctatcttgg acggcctaca agacccaacg tttggaaatg tcgatcttgc ttcacatgat
    25681 tgttaatggg attgctttct gtttgttggc tcttgtggtg attatgagtc ggacattagg
    25741 aatttctgtg taaaagtttt tatgtaggaa ccgacctctt tctactaggg aaagatgaat
    25801 gcaatcgtgt ccatcttttt ctttttatgg taaaatagaa aaataatatg atgaaaatcc
    25861 ttgagggagt gaccgatatg tcaagtaaag ccaatcatgc aaagacagtt atttgcggaa
    25921 ttatcaatgt aaccccagac tccttttcgg acggtggtca attttttgct cttgagcagg
    25981 cactccagca ggctcgtaaa ttgatagcag aaggagccag tatgctcgat atcggcggag
    26041 aatcgactcg gccgggcagt agctatgttg agatagaaga ggaaatccag cgtgttgttc
    26101 cagtgatcaa agcgattcgc aaggaaagtg atgtccttat ttctatcgat acttggaaaa
    26161 gtcaggtggc agaggctgct ttggctgctg gtgccaatct agttaatgat atcactggtc
    26221 tcatgggcga tgaaaaaatg gcccatgtgg ttgctaaagc tggagcgaaa gtagtcatca
    26281 tgtttaatcc agtcatggct cgacctcaac atcctagttc gcttatcttc cctcattttg
    26341 gctttggtca aacctttaca gaaaaagagt tagctgactt tgaaacattg ccaatcgaag
    26401 acttgatggt ggctttcttt gaacgagcac tagcgagagc ggcagaagct ggtattacac
    26461 cagaaaatat cctgttggat ccaggaattg gctttggtct gaccaagaaa gaaaatctcc
    26521 tccttttacg ggacctggat aaactacatc agaagggcta tccaatcttt ctcggagtgt
    26581 cgcgcaagcg atttgtcatc aatatccttg aagaaagtgg gtttgaagtc aatcctgaga
    26641 cagagcttgg tttccgaaat cgggacacgg cttcggctca tgtaactagt atcgctgcga
    26701 gacagggtgt agaagtggtg cgcgtgcatg acgtagctag tcacaggatg gcagttgaaa
    26761 ttgcctctgc cattcgtctg gctgatgaag cggaaaattt agatttaaaa caatataaat
    26821 aagatgaaag aaattgaaaa caatcagtgg attgctaact accggacgga tcaaccgcat
    26881 tttggattgg aacgaatggt ggaactgtta gctttgcgtg gcaatcccca tctcaaactc
    26941 aaggtcctcc atatcggagg gactaacggc aagggctcga ctattgcttt tttgaaaaag
    27001 atgctagaaa agctagggct gagagttggc gtgtttagct cgccctatct cattcattac
    27061 acagaccaga ttagcatcaa tggggaatcg atctcagaag cgaggctaga agctctcatg
    27121 gcagactatc agtctttgct ggagggagaa gcggtcgcca atttacaggg cacaaccgag
    27181 tttgagatta tcacagccct ggcctatgac tactttgcct cagagcaagt agatgtggcc
    27241 atcatggaag ttggcatggg tggacttttg gatagtacca atgtctgtca gcccattttg
    27301 acaggaatta caactattgg cttggatcat gtggccctac ttggtgacac cttggaggcc
    27361 atagcagagc agaaggcagg tattatcaaa caagggatac ccttggtaac agggcgtatt
    27421 gctccagaag ccttgactgt gattgaccgc attgcggaag ggaaagatgc gccgagactt
    27481 gcctacggga cagattatca ggttcgtcat caagaaagtg tggtgacagg ggaagtcttt
    27541 gactatacaa gtgctgtcag acaaggtcgc ttccagacta gcctgcttgg tttgtaccaa
    27601 atagagaatg ctgggatggc catagcttta cttgatactt tttgtcaaga agatggtcga
    27661 gagctagcaa gcaatgactt tcttggtcaa gccttggaag aaacaagttg gccagggcgt
    27721 ttggaaatcg tgtcaagaga tcccttgatg attttggatg gagcccataa tccccatgct
    27781 atcaaggcct tgttggtaac cttgcaagaa cgttttgcgg attatcataa ggaaatcctc
    27841 ttcacttgta tcaaaaccaa agccttggag gatatgttgg acttgctggg agccatgcca
    27901 gataccgagc ttactctaac acattttgcg gatagtcggg cgacggatga aagcgtgctg
    27961 aaagaggcag ctaagtctag aaatctcagc taccaagatt ggcatgattt tctagagcag
    28021 aatttgacag ataaaaaaga agagaaacaa acagttagga ttgtcacagg ttccttgtat
    28081 ttcttgagcc aagtgagggc ctatctgatg gagaggaaga acgagaatgg atacacaaaa
    28141 gattgaagca gctgtaaaaa tgattatcga ggctgtagga gagaacgcta atcgcgaggg
    28201 cttgcaggaa acacctgctc gtgtagcccg tatgtatcaa gagatttttt caggtcttgg
    28261 tcaaacagca gaggaacatt tgtcaaaatc ctttgaaatt attgacgata atatggtggt
    28321 agaaaaggat atctttttcc ataccatgtg tgaacaccac ttcttgccat tttatggtag
    28381 agcgcacatt gcctacattc cagatggtcg tgtggcaggc ttgtctaagc tagcccgtac
    28441 ggttgaagtt tattcgaaaa aaccacaaat tcaagaacgt ttgaatatcg aagtggccga
    28501 tgccttgatg gactatctag gtgctaaagg agcctttgtt gtcattgagg cggaacatat
    28561 gtgtatgagt atgcgtggtg ttagaaaacc aggcactgca accttgacga cagtagctcg
    28621 tggtctattt gaaacagata aggacctccg cgaccaagct tatcgtttaa tggggctata
    28681 aaaagaatcc gcttcaagcg gatttttcta gaaaggaatc attatggatc aactgcagat
    28741 taaggatttg gaaatgtttg cctatcatgg tctttttcct agtgagaaag aattggggca
    28801 gaaatttgtc gtttcagcca tcctatccta tgatatgacc aaggcagcta cagacttgga
    28861 tttaacagcc tctgtccatt acggagaatt atgtcagcag tggacgactt ggtttcagga
    28921 aacgagtgaa gatttgattg aaacggtagc ctataaactg gtggaacgta cctttgagtt
    28981 ttatcctctt gtccaagaaa tgaagttgga actgaaaaaa ccttgggcac cggtgcattt
    29041 gtcactagat acttgctcgg taaccattca tcgccgcaag caacgagcct ttatcgccct
    29101 aggaagcaat atgggagata aacaagcaaa cttgaagcaa gccattgaca aactgcgagc
    29161 tcgtggcatc tatattctca aagagtccag tgtcttagcg acggagcctt ggggtggagt
    29221 ggagcaggat agctttgcca atcaagtggt tgaggtggaa acctggctac cagcacaaga
    29281 cttgttagaa accttgttag ccattgagtc agagctggga cgggtgagag aagtgcattg
    29341 gggacctcgt ttgattgatt tggacttgct ctttgtggag gaccagatcc tttatacaga
    29401 cgacctcata ttgcctcatc cttacatagc ggaacgcctt tttgtccttg agtccttaca
    29461 ggaaattgcg cctcatttta tccatccgac attaaaacaa ccgatccgca acttgtatga
    29521 tgctttgaaa aaatagaaaa actctagttt tcagttactt gcaactgaag gctagagttt
    29581 ttaaaatagg tcattttctt ctgggaggag gatagtttct ctaccgtaca tgtctaaaac
    29641 cagtactctt gggggataac gagggtcgaa aggatggtta aagtcaaaat caatggctgt
    29701 agggaggtgt tgacttgaaa agtggaaggt aatctttcct tggttattaa gcaattgaaa
    29761 ctcgagttct tcttccaatt caaagacatt ttttaagaaa tgatcgatga tataccaaaa
    29821 agagtcaatg atgtcatcgg gcaagctggt aacaatgcca aaactagcag accgcatgtg
    29881 ggtattggta aaagccatat ctctgtcccc tttcttttcc cttatcatac agcaaatagg
    29941 attaaaaatc aagaaaaggt gattttttga aaaggatttt aactacaggg aaaaataagg
    30001 aaaaaaattc ccaaaaatct accgaagtta ataggtaaat tcccaaatta acttgattat
    30061 ataactttca gtta
//
LOCUS       DAVAZV010000022        29758 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVAZV010000022 DAVAZV010000000
VERSION     DAVAZV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.022"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            132..494
                     /locus_tag="VQT46_000968"
     CDS             132..494
                     /locus_tag="VQT46_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371013.1"
                     /translation="MRLASESRQILDKLKDDVYNKLGYEVSYSSIVSQAVREYVPKKE
                     RIDWIKLKETAIPFSSLKQSNNWEYQTSLMLEKDVLILLSELQNFFLDVFQAKRIHRA
                     FCIRLCLRAQFLLSNNDS"
     gene            902..1201
                     /locus_tag="VQT46_000969"
     CDS             902..1201
                     /locus_tag="VQT46_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371014.1"
                     /translation="MNRNVLNFLRTESAERVSLYIDKANRLEGDVTLLAPSSQDLEDI
                     KNAMFSNPNLELKVARLDVMKKIAYASTRNHYLTGATIFGDISKGTYNCDPKSYV"
     gene            complement(1296..1733)
                     /locus_tag="VQT46_000970"
     CDS             complement(1296..1733)
                     /locus_tag="VQT46_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371015.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLA
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGVLTIDFLFFVLLAFISSQRFSSLMP
                     IITACHSTFYYMTADYLRENYPDFYDKHISNTYTILSISSFLV"
     gene            complement(1864..2498)
                     /locus_tag="VQT46_000971"
                     /pseudo
     CDS             complement(1864..2498)
                     /locus_tag="VQT46_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
     gene            complement(2709..3359)
                     /locus_tag="VQT46_000972"
     CDS             complement(2709..3359)
                     /locus_tag="VQT46_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET2371016.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRMHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            3471..4313
                     /locus_tag="VQT46_000973"
     CDS             3471..4313
                     /locus_tag="VQT46_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET2371017.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            4389..4826
                     /locus_tag="VQT46_000974"
     CDS             4389..4826
                     /locus_tag="VQT46_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET2371018.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKKSKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTDIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            4894..5196
                     /locus_tag="VQT46_000975"
     CDS             4894..5196
                     /locus_tag="VQT46_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371019.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(5287..6360)
                     /locus_tag="VQT46_000976"
     CDS             complement(5287..6360)
                     /locus_tag="VQT46_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET2371020.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDKLAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHKIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            6516..7193
                     /locus_tag="VQT46_000977"
     CDS             6516..7193
                     /locus_tag="VQT46_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2371021.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            7186..8160
                     /locus_tag="VQT46_000978"
     CDS             7186..8160
                     /locus_tag="VQT46_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2371022.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVEMQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLLLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQEICIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQT46_000979"
     CDS             complement(8209..10152)
                     /gene="thrS"
                     /locus_tag="VQT46_000979"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET2371023.1"
                     /translation="MINITFPDGAIREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHGDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(10210..10386)
                     /locus_tag="VQT46_000980"
                     /pseudo
     CDS             complement(10210..10386)
                     /locus_tag="VQT46_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
     gene            complement(10393..10533)
                     /locus_tag="VQT46_000981"
     CDS             complement(10393..10533)
                     /locus_tag="VQT46_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET2371024.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQ"
     gene            complement(10964..11164)
                     /locus_tag="VQT46_000982"
     CDS             complement(10964..11164)
                     /locus_tag="VQT46_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371025.1"
                     /translation="MRRFYSHLPYYLVILFFYWPLYELFLLVVSDPLTLKGLYINNLL
                     FFTPMVILIVSLLYSYRFRFSL"
     gene            11403..11948
                     /locus_tag="VQT46_000983"
     CDS             11403..11948
                     /locus_tag="VQT46_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET2371026.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     LYIDETKTTRLLDTPDFPEEFKSLAKAQADELDLLRTKNNLNWAFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKRNKPD"
     gene            12174..12443
                     /gene="rpsO"
                     /locus_tag="VQT46_000984"
     CDS             12174..12443
                     /gene="rpsO"
                     /locus_tag="VQT46_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET2371027.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            13259..13873
                     /locus_tag="VQT46_000985"
     CDS             13259..13873
                     /locus_tag="VQT46_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET2371028.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAIVGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(14165..14914)
                     /locus_tag="VQT46_000986"
     CDS             complement(14165..14914)
                     /locus_tag="VQT46_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET2371029.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            15047..17383
                     /locus_tag="VQT46_000987"
     CDS             15047..17383
                     /locus_tag="VQT46_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET2371030.1"
                     /translation="MDKNKIMGLTQREIKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAVASILTSYMA
                     HSEDKNPTAQAIRQRFQGQVVYPMLSNLPFSSDRKWGAMELEGLGIVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            17485..18162
                     /locus_tag="VQT46_000988"
     CDS             17485..18162
                     /locus_tag="VQT46_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET2371031.1"
                     /translation="MISKRLELVASFVSQGAILLDVGSDHAYLPIELVERGQIKSAIA
                     GEVVEGPYQSAVKNVEAHGLKEKIQVRLANGLAAFEETDQVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            18149..18946
                     /locus_tag="VQT46_000989"
     CDS             18149..18946
                     /locus_tag="VQT46_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET2371032.1"
                     /translation="MLASEVIHAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            18963..20066
                     /locus_tag="VQT46_000990"
     CDS             18963..20066
                     /locus_tag="VQT46_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET2371033.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            20073..20264
                     /locus_tag="VQT46_000991"
     CDS             20073..20264
                     /locus_tag="VQT46_000991"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371034.1"
                     /translation="MKIKEQTRKLAAGYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            20367..21386
                     /gene="galE"
                     /locus_tag="VQT46_000992"
     CDS             20367..21386
                     /gene="galE"
                     /locus_tag="VQT46_000992"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET2371035.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTATLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAIEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            21388..22341
                     /locus_tag="VQT46_000993"
     CDS             21388..22341
                     /locus_tag="VQT46_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2371036.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTYYLDYPNVERQAGKTSWSFRKLFFYSIE
                     GIINFSDFPLIIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDDRLKKIEFI"
     gene            22493..23158
                     /locus_tag="VQT46_000994"
     CDS             22493..23158
                     /locus_tag="VQT46_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371037.1"
                     /translation="MLSKEDYTEEIGLIKKQNYVEAELYPIVADIIKPTLKDSLSKRY
                     VFGRQRRGLGQIYYGLSNFPDIVILDKTYENKSRKSIKIEEWKKLRGCVEVKNLNYSL
                     ITEEKIKSTISNSFEHITGEMEQLTGEMGQLIGDLLWYKKVIYTNGIEWRFLSLDDKE
                     EIDNTIVEVVNKRIETEEAGNSFDWWKNIKDLSFNYTDICLSKDCRQEWNEFVKRVKE
                     IEW"
     gene            23197..23298
                     /locus_tag="VQT46_000995"
                     /pseudo
     CDS             23197..23298
                     /locus_tag="VQT46_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677122.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group 2 glycosyl transferase"
     gene            complement(23349..23555)
                     /locus_tag="VQT46_000996"
     CDS             complement(23349..23555)
                     /locus_tag="VQT46_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET2371038.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            23607..24083
                     /locus_tag="VQT46_000997"
     CDS             23607..24083
                     /locus_tag="VQT46_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET2371039.1"
                     /translation="MAKEPWQEDIYDQEESRAERRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            24092..24763
                     /locus_tag="VQT46_000998"
     CDS             24092..24763
                     /locus_tag="VQT46_000998"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET2371040.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDFETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            24894..25232
                     /locus_tag="VQT46_000999"
     CDS             24894..25232
                     /locus_tag="VQT46_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET2371041.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLADGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            25235..25864
                     /locus_tag="VQT46_001000"
     CDS             25235..25864
                     /locus_tag="VQT46_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET2371042.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITKHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            26104..27255
                     /locus_tag="VQT46_001001"
     CDS             26104..27255
                     /locus_tag="VQT46_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2371043.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            27568..28317
                     /gene="truA"
                     /locus_tag="VQT46_001002"
     CDS             27568..28317
                     /gene="truA"
                     /locus_tag="VQT46_001002"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET2371044.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFTVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            28307..29080
                     /locus_tag="VQT46_001003"
     CDS             28307..29080
                     /locus_tag="VQT46_001003"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET2371045.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            29058..29519
                     /locus_tag="VQT46_001004"
     CDS             29058..29519
                     /locus_tag="VQT46_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2371046.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
BASE COUNT         8719 a         5366 c         6692 g         8981 t
ORIGIN      
        1 taaattttta gattgtggaa tttttttcaa cttaattctt gatttttttt ctaaattgtt
       61 atatacttaa tttacgggat aacagaatcc cgtcagaaag gggtgataat atgggaaaag
      121 agaatgttag aatgcgttta gcgtctgaat ccagacagat attagataag cttaaagatg
      181 atgtttacaa taaattaggc tatgaagtaa gctattccag tattgttagt caagctgtta
      241 gagaatacgt tcctaaaaaa gaacgtatag attggataaa attaaaagag acagctatac
      301 ctttttcatc gttaaaacag agcaataatt gggagtacca gacatcactt atgttagaga
      361 aagatgtatt aatcttactg tctgaactac aaaatttttt cttagatgtc ttccaagcga
      421 aacgtataca tagggcattt tgtatacgtc tatgtttgag agcgcaattt ttattaagta
      481 ataatgattc ttaatactat caatattaat gcggagtgta atgctccgca aaaataaaac
      541 ctattacggg ataaaaacac tactttattt aggatggaaa taagaacgta ttttttacta
      601 atattgttta gaaaggagtt tctttatgac accagaagaa caaactgctt tggaatactt
      661 ttatgaggaa ctcgagagtt acggtgaaga tgagcaagga gaggtctttg atttgtatga
      721 taattaaatc atctccatag tttctgagaa taattgagaa actatactct aaatcatagg
      781 tttatgtaaa gctagatata cacaaaagga ggtacgaatg aagatgaaag ctagagcttc
      841 accgttgaat tgattttgtt tctagaaaaa atcaataatt agaaaaatac gaggtaaaaa
      901 aatgaataga aatgtactaa attttctgcg aacagaaagt gctgaaagag ttagtcttta
      961 tatagacaag gctaatagat tggagggcga tgtaactcta ctcgcaccta gttctcaaga
     1021 tttggaagat attaaaaatg ctatgttttc caatcctaat ctcgagctaa aagtagcgag
     1081 actggatgtg atgaagaaaa tagcatatgc ttctacaaga aatcattatt taacaggggc
     1141 tacgattttt ggggatattt cgaaaggaac atacaattgt gatcctaaaa gttatgtcta
     1201 atataaggga ggttaatccc tccccttgtt tttgaaaatc gaaaggaaaa gtataaaaat
     1261 gaaagttaat gaatatttct ggagaacgag ctgtcttata ctaaaaaaga agaaatcgat
     1321 aaaatagtat acgtgttaga gatgtgtttg tcgtaaaagt ctggatagtt ttctcttagg
     1381 tagtcagctg tcatataata aaaagtagaa tggcaagcag tgatgattgg cataagagat
     1441 gaaaaacgct gagaactaat gaaggctaag agaacaaaaa atagaaaatc aatggtgaga
     1501 acccctaaat agtagaagcg aatcttttta ttgatttgag gataaatctc agcgaattga
     1561 tgtttgagtc ggacgaccaa gagaaatagc aggagtcctt gagcaaggaa gaaaattaaa
     1621 ccagagagca agagccactc aaaagatgtc tcgagtctag tgataaaaaa tgcaaatagt
     1681 agcaaatcaa taactgcaat tgctataaaa tggattctat agagtttttt catgacaaga
     1741 cctccctctt ttatctaact tcattctact ctaaaagaat gggagttaca actaaaatga
     1801 taaaaatagc agaggggaga ttctcttaag ttggctagta ttctttattt gagtttcctt
     1861 ctattatcta acttcttcat cattccagac aaataaagct ccgattgcat tgaggatata
     1921 aaagatgtat ttaccgatat tggcgaagtt tccttgaata ccagcttttg tcagctgaac
     1981 gaaattgtaa atcaaccaaa agccccactg tccctcattg ccaatgcatt caaagcattg
     2041 gcaatgaggg acagtgcaaa ggcaatagtt gttacgtagg caaggagatt catcttgccc
     2101 ccatatccga tatagttggt cacaaaggca aagaggaagg cgatgatgga aatgatgatg
     2161 gccgccaatt ttacctgttt ttggctcatt tggttgggtc tgccttcttg cgaagctttc
     2221 catttcttta tagcaaaggt ataaatgagg aaggtgacgg gataggtaat gatggccgcc
     2281 ttatttccaa ggatataatc aatagcaccg gacaaaatgg tattaacaat accaaagtaa
     2341 ttttcccatt tgcttaattt ccccgtgaaa cgagtggaca acatggaaat cccaacgttg
     2401 gttacggaaa tcaatccaaa gggtacaaga gctgtccatg gtccccagtc tacaaattta
     2461 tcgaggcgtg agttgaggta accagatgca atcgcaatcc aacgaccaaa gcaaccccga
     2521 agaggtcaaa ctatttagat gtagcaaaaa tttttagtga ttttttcata ggttaaacta
     2581 cctttctttt tttcaaatat tctcccattt ttttttcaaa tattctacca ccaaatgaaa
     2641 gtaaaataaa atgatagaaa taaaaccctg aaaataaaac tttcagggtt ggtaggggac
     2701 ttgagaaatt agttgatttt ctcgacatag agttgttttg caatgtccat attcacttgt
     2761 aaatcctcgt cgttactgag gatagtgaag gtattgctga agccatcaaa ctgcttaact
     2821 tggagctggt caccgatgtg aagtgagtgc ttgtccagat aatggagaat gtcaaaacta
     2881 tcgtgcatcc gagtcaggcg gtaggcgcca gcttccttga tatcagctag tgggaggtta
     2941 ttgatttcaa cgaggagttc tcccttggca ggaatagttc ctccgtgggg gcaggtttta
     3001 gggaaaccta gcagtttatc tagtctttcc acgaacaggt cagagacagt gtgttccaag
     3061 acctcagctt cctcgtgaat ctggtcactt gtatagtcta aatgatgaac tagaaaaact
     3121 tcaatcaagc ggtgcttacg atagagctca gagaccagtt tgagaccgag gtcagtcagt
     3181 agatagccac attccttgtc ctttaggatg agattttcac ttttcattcg tttgatcatt
     3241 tcagttacgg cagggggaga gacttgcatg cgagccgcaa tttccttgtt ggtaatctta
     3301 tgcaggtcta tgccaatttc ataaatacat tttagatagt cttctttgtt tggggtcatt
     3361 cgtttcctct tgtctaatat ctttatctag tatatcaaaa aaagctagat ttctctagct
     3421 gtgacttttt atgttatact tattgcaaga gaaaaaacga ggagatggat atgacgaaaa
     3481 tagctcttct ttcagatatt catggaaata ccaccgcctt ggaggctgtt ttggcagatg
     3541 ctcggcagct aggagtggat gaatactggc ttttgggaga tattctcatg ccagggacag
     3601 ggcgtagaag gattttggac ttgttggatc aactaccgat tacggctaga gttttgggaa
     3661 actgggaaga cagtctttgg catggtgtcc gtaaggaatt ggatagtact cgccctagtc
     3721 aacgctatct cttgcgccag tgccagtatg ttttagagga aatttcccta gaagaaattg
     3781 aagtgctcca caatcaacct cttcaaattc atcgtcagtt tggggatttg acagtgggaa
     3841 ttagccatca tctgcctgat aagaactggg ggcgagagtt gattcatact ggcaaacaag
     3901 aggaatttga ccgcttggtg actcatcctc cctgtgatat tgctgtttat ggacacattc
     3961 accagcagtt gcttcgttac gggactggtg ggcaattgat tgtcaatccg ggttcgattg
     4021 gccaaccttt ctttttggac gctcagctac ggaaggactt gcgggcccag tatatgattt
     4081 tggagtttga tgacaagggc ctggtagata tggacttccg acgggtagat tacgatgtgg
     4141 cagctgaatt gcagctggct aaagacctga gacttcccta ttttgaggtt tactatgaaa
     4201 gtctggtcaa tgggatccac catactcatc atcaggaatt tttgagagaa ttggctcaga
     4261 aagagggttg cgatcgggag ttagacgact ggttgaaaag tggtaacgat tgacattaca
     4321 actaaaaagg gtataataat agaaaaagaa gagtagaggc agggtagcct cgtaaaaagg
     4381 agaagaggat gcaaattcca agtagattta ccattgcgac tcatatgctg ataatcattg
     4441 ccctcgaggg gaagaaaagc aaggtgacca gtgattttct ggctgctagt gtcggggtca
     4501 atcctgtcat tatcagaaag atcttgtccc agttgaagaa ggcagagctg atttcagtag
     4561 cgcgtggaac gggcggaaca gatattgtca aggaccttaa ggatattagt cttttagatg
     4621 tttatcaggc ggtcgaatgt cttggtaaga caggtcaact cttcagtttc catgacaatc
     4681 cgaatccaaa ttgccctgta ggagctcata ttcatgatgt tttggatcaa aaattggaga
     4741 gaattcagtt gactatggag gcagaacttg gtcaaaccag tctagaaaaa gtcgtggccg
     4801 atgcagagag tcagatgaag gattaagagg gataaatgcc ctcttttttc tttggataat
     4861 tatgataaaa tgtagctatt aaaggagtaa gaaatgtatc tcgttatagg aattgtatta
     4921 gcctttatag tgtcattttg gaaggataat agaagtttgt ggaatccagt attattttta
     4981 ttatccctca tttcaagtta tttttatcta tcctaccttt tttataaaaa tggatacgag
     5041 aatgttcagt tagcttttta tgtatttgcc tttgtcttac ttcctttttt gctttttcta
     5101 agtggcatct ttttaatcta taatggggtc attttgttga agcgagaggg acgttccaag
     5161 ccccattatc tctcaatgct ctttgatttt tattgactat tagattctat ttaaaaagac
     5221 ttagaatgca catgaaagta tgtattctag gtcttttgtt ttgtatacat ttaattttca
     5281 agagtattat ctatttttcc atgcctggta acgagtatca atcaataact gggtaaggcg
     5341 acccaaggtt tctctttctt ctggagtgag ggattgagct tggacaaaga gatgatgaat
     5401 gtattcaagc gcctttaagg aagccaagtc attgatagag ctaataccag cctcaagaat
     5461 agtgccaaag aagaggtcga agtagagctg aagttcttcg tcagggactg tggccaccca
     5521 ttctttaaag gttgtgtcta cttgctggct atcactgttg gtcttatcca gttggacgaa
     5581 gtgcttgtcc tcaatctgcc aactaaaggt atcgtgctgg gcgatgccac ccagggcagt
     5641 actctgaacg atgattttgt gagcaggaat ttccagcatc ataccgataa tggaaccttg
     5701 tggaatgaat atcttgcttc tatccattat cctttgataa cccgcagtct gtgtcaattc
     5761 ttgatggaga ccaggtgcat caaatgtata aactgctgtg atctgatttt gcaaactttg
     5821 ctcaatttgg ctagcagcat agatagcgag atttcctccc ttggaatgcc cagctagaat
     5881 aaccttttgc ttaggatgat gggcaaaaaa gttctttaaa tagcgaaggg cgtgcttttg
     5941 agcaggaatt tccttcatat aggtcaggtg gaaatcttcc ttccagccaa tgatactgtc
     6001 atctgtccca cgaaagacaa tcagataggt atcgaggctg acacgataag tcatagccgc
     6061 aaattgcttt tgcagttcag ggtcgatgtc gttgataaaa tgggagagtt tgcaattttt
     6121 gaagcgcttg tgttgagcca atttatctaa taattgaagg cgatttttgc tagtaagcat
     6181 ggtgggctct cttggaacct gaggtgctag atctaaaaga cgttgaggaa gtgtggagac
     6241 cagattatca aaggagaggt aggtgatttc tattaaggtt agaatgtcta actcattcaa
     6301 gggaaggtcg taataagaat catatgcgac atctttcaga tagtcaaaaa tattggccat
     6361 aagagctcct ttctttttat ttatcttagc aaatttccct caaattagct agtagcatag
     6421 cctgtttgca ctggctaaaa acaggctatt tcaaattcag tttcagacca tctagcatgg
     6481 aaaaatctgt tataataatg gaaaaggaga agcgcatgca caagatttta ttaatagaag
     6541 atgatcaggt cattcgtcaa cagattggga aaatgctctc tgaatgggga tttgaagtgg
     6601 tcctggtaga agactttatg gaagttttga gtctatttgt tcagtcggaa cctcatctgg
     6661 tcctcatgga tattggtttg cccttgttta atggttatca ctggtgtcag gaaatccgca
     6721 agatttccaa ggtacctatc atgtttcttt cttcgagaga ccaggctatg gatattgtca
     6781 tggcaatcaa tatgggggcg gatgactttg tgaccaagcc ttttgaccag caggttcttt
     6841 tagctaaggt tcagggcttg ttgcgtcgtt cctatgagtt tgggcgtgat gagagtttgc
     6901 tggaatatgc tggtgttatc ctcaatacca aatccatgga tttacattat caagggcaag
     6961 tcttgaattt gaccaagaat gaattccaga ttttacgcgt gttatttgag catgcaggca
     7021 acatcgtagc acgtgacgac ctgatgcggg aactttggaa cagtgacttt ttcattgatg
     7081 ataataccct ctctgtcaat gtggctcgtt tgcgtaaaaa gttggaggag cagggattgg
     7141 taggatttat cgagaccaag aaaggaatag ggtacggatt gaagcatgct tgattggaaa
     7201 caattttttc tagcctatct gcgctcccgt agtcgtcttt ttatctatct gctttctttg
     7261 gcatttcttg tcttactctt tcagttttta tttgccagtc taggaattta cttcctctac
     7321 tttttcttct tgtgttgctt tgtaaccatc ttatttttca cttgggacat attggtggaa
     7381 atgcaggtct atcgccagga acttctctat ggagagaggg aagccaagtc tcctttggaa
     7441 atagctttag cagaaaaatt agaagcgcgt gagatggaac tctatcagca gaggtcaaaa
     7501 gcagaaagaa aactgacgga tttgctggat tactatacct tgtgggtcca tcagataaag
     7561 acccccattg cagccagtca actcttagtt gcagaagtgg tcgaccgcca actgaagcag
     7621 cagctagaac aggaaatttt caaaatcgac tcttatacca acctagtttt acagtacctg
     7681 cgtttagaaa gtttccatga tgatttgctc ttaaagcagg ttcaaattga ggacttggtc
     7741 aaggaaataa ttcgtaaata tgctcttttc tttattcaaa aaggcttaaa tgtcaatcta
     7801 catgaccttg ataaagaaat cgtgacggat aaaaagtggc tgctagtggt tattgagcaa
     7861 atcatctcaa acagtctcaa gtacaccaag gaaggtggtc tggagattta tatggatgac
     7921 caagagattt gtatcaaaga tacgggaatc gggataaaaa acagtgatgt cctccgagta
     7981 tttgaacgtg gcttttcagg atacaatggc cgtttgaccc agcagtcctc tggacttggc
     8041 ctttatctat ctaagaaaat ttctgaagaa ctggggcacc agattcgtat cgagtctgag
     8101 gtcggaaaag gaacgacagt gcggattcag tttgctcaag tgaacttagt ccttgagtaa
     8161 aaatagatga gaaaaagcct ccagattgga ggcttttatg ctagactctt atttctcaac
     8221 gcgtgatttg ttggcgatat cagctaggat agcttgaaca aaattatcaa ctgagacagt
     8281 ttgtgtttct ttttggccgt agcgacgaac gttgactgtt tcgtcttcca tttctttgtc
     8341 tccaacaatt aattggtaag gaatcttgct ggtttgtgaa gcacggatct tgaactgcat
     8401 tttttcattg cgctcatcta cgtctgcacg gacaccgcgg tcacggagtt tcttggctac
     8461 ttcccaagcg tagtccacgt gtttttcgtt agatactggg atgagggtta cttggtgtgg
     8521 tgccagccat gttgggaagg cccccttgta gttctcaatc aagatagctg tgaagcgttc
     8581 catagttgag ataaccccac ggtggatcat gactggacgg tgatcttcgc catcagctcc
     8641 gatgtatttg aggtcgaagc gttctggcaa caagaaatca agttggatag tagaaagggt
     8701 ttcttctttt ccaagggcag ttttaatctg gatatccaat tttggtccgt agaaggctgc
     8761 ttcaccttcg gcttcaaagt agtccacgcc catttcatca agagctgcac gaagcatggt
     8821 ttgggcattt tcccacatct catcgttatc aaagtactta tgagtatctt gagggtcacg
     8881 aagagagagg cggaagcggt agtcagtcaa gttgaagtct tcataaacat cgataatcaa
     8941 ctgaagggca cgttggaatt cttcttggat ttgttctgga gtaacgaata ggtgaccgtc
     9001 gttgagtgac atttcacgta cacgttgaag gccagtgagg gcaccagatt tttcgtaacg
     9061 gtgcatcata ccgatttcag cgatacggat tggcaattca cggtaagagt gaacatggtg
     9121 tttgaaaact tggatgtggt gcggacagtt cattggacga aggacaaatt cttccccgtc
     9181 acccatgtcc atggttggga acatgtcttc ttggtaatga tcccagtgac cagaagtctt
     9241 gtaaagctca acagaagcaa gtggtggagt gtagacgtgt tggtagccag aagccaactc
     9301 tttgtttacg atgtagcgtt ccaattcacg acggatagtc gcaccatttg gcaaccagaa
     9361 tggcaaacct tgtcccactt cttgtgaaat cataaagagg tcaagctctt taccaagttt
     9421 acggtggtca cgttccttag cttcttcacg catttgaagg tagtttttca agtctttctt
     9481 gtcaaaccaa gctgtaccgt agatacgttg catcatagcg ttgtcgctgt ttccacgcca
     9541 gtacgcacca gctacatgga gaaggtggaa gatttggata cgacctgttg atggaacgtg
     9601 aggtccacgg cagaggtcta catattcacc ctgacgatag atagtcaaac cgccttcgtc
     9661 ttctgagtgt tcttcaatca attccaactt gtaagggtca tttttgaaga tttcacgtgc
     9721 ctcgtcttta gtcacttctt cacgaataga tgggaagttt tctttgacga ttttttgcat
     9781 ttcttcttcg atacgaggaa ggtcttcgtt agagatttga ccagctgtgt tgtcagtatc
     9841 gtagtagaaa ccatcttcga tggctggacc aactcccaag tgaatgtctg ggaaaagacg
     9901 acgagctgct tgggcgaaca agtgagctgc tgagtgacgc aagattggaa gggcatctcc
     9961 gtgatcaggt gtcacaattt cgatgcttcc atcttcagtg atagcgcgag tagtgtcgat
    10021 gagtttgccg ttgaatttac cagccaaggc ttttttagct agggaattgc tgatagattg
    10081 ggcaatttca aaagttgtta cgccagattc gaattcacga atagcgccat ctgggaaagt
    10141 aatgttaatc atgatgttct ccttttttat tatttcatag tttctaagca ttgatttttt
    10201 atcagcagac tacttccaag ttctaacgtt caattgcttt tctttatcag agaggaagtt
    10261 ttccatttcc gtcagaatat ctatatccaa acgttgagaa agttctaata gtcaccagat
    10321 attttctgaa agtttttgtt ccagtgtgta gggtgtttca tcatagtagc gtccttgctt
    10381 tgtcatcacc agtcattgga aatttccaat atcattagat aaagccaaga ggtcttcttc
    10441 taccgtccac ttgaaatcat gatgcttaac ttccagttcg tgataagctt gtcggattgc
    10501 ccaactgcgc tccactaatt cttgcaactc cataattagt atcctaataa aaaaatgcga
    10561 catcctcgaa aggacgtcgc aacgtggttc caccttcatt tatgtacctc aaaagagagg
    10621 gacacctctg atcggctcta acgtggccac cgttttatgt tttcataaaa aactcaagag
    10681 tagtatcagt ttagacttcc tatgcgtttc cagcaaccac gcactctcta gtagaaaggg
    10741 actaagtgac ttgtctctat ggattattat agcatgattg tgagattttt caaggatttt
    10801 gtgaaagttt tttgtttttc attttttgta gaatatgctt gatgctaata ccagaatcca
    10861 tgcccaccag agcaactgtt tcatagatta gcaagtaaat tagtataaac acaccaaagg
    10921 ttatgatagt aaagtaaaag agcagtccgt taccaactaa ccatcaaagt gagaaacgga
    10981 aacggtagct atagagtaac gatacaatca agattaccat aggtgtaaag aagagaagat
    11041 tgtttatata gagtcccttg agtgtaaggg ggtcagaaac aactagcaag aacaactcat
    11101 aaagtggcca ataaaagaat aatatgacca gatagtaggg gagatgggaa tagaatctac
    11161 gcatgataat cacctcgttt taaaaaaaca gacaacttag atctcttgct atgattatta
    11221 tagtatgttt aaaacaagaa agtaaatttg ttgacaaaga agatttttct tttcactaga
    11281 atcatggtta gttttcttgg tagaaatatt ttgataataa ttaagcaaga ctattgacat
    11341 tgattattaa gagtgtcaca attgttgtaa ctaaaataat tacaacaaga ggggtataaa
    11401 aaatgaaact agcagttatt gcagcaaatg gacaagcggg gaaggcaatt gttgaagaag
    11461 cagtcaaacg aggacatgaa gtaacggcta ttgttcgttc tgaaaacaaa agtcaagctg
    11521 agtctattat taaaaaagat ttatttgagt tgacaaaaga tgatcttact ggatttgatg
    11581 ctgttatttc agcgtttggt gcttatacac cagatacgct accgctccac agcaaatcaa
    11641 tcgaactatt taatcagctt cttgctggaa cacagacacg ttttctagtt gtagggggat
    11701 caggaagcct ttatatagat gaaacaaaaa cgacacgact tttagatacg cctgattttc
    11761 ctgaagaatt taagtcacta gcaaaagctc aagcggatga attggatctt cttcgtacaa
    11821 aaaataatct caactgggct tttgtcagtc ctgctgtaga ttttattccc gatggtgaaa
    11881 aaacaggaaa ctacattcta gcaggagaaa tttttactac taatgaaaaa aggaataagc
    11941 cagattagtt atgcagatta tgctattgga ttggtagatg aacttgaaaa aggtcatcat
    12001 ataaaagaac gtatctcttt acttgaaaaa taataactat gagagtatta atgtttgaca
    12061 gaaaatttaa atcttggtag aatagggatt gtcgtaaaga caaataactt cttcttggtt
    12121 acaggcatgc caacctgtca ctcggatgaa gccaaataaa aaggagaaac atcatggcaa
    12181 tctcaaaaga gaaaaaaaat gaaatcatcg cacaatatgc acgtcacgaa ggtgatacag
    12241 gttcagtaga ggttcaagtt gctgtcctta cttgggaaat caaccacctt aatgaacaca
    12301 tcaaacaaca caaaaaagac cacgctactt accgtggatt gatgaaaaaa atcggtcgcc
    12361 gtcgtaactt gcttgcatac ttgcgtaaaa acgacgttaa ccgttaccgt gagttgatca
    12421 actctctagg acttcgtcgc taattcaaga tacaaaggct gtcaaaagca caaagtaaaa
    12481 ataggaaaat ttacgaagaa acttcagttt ctaggagatt ttatcttttt tgccaagtgc
    12541 ttaggccgtg ttcaattgag catatcttga taatgaagct actctaaatt gggtagcttt
    12601 tttgtgttgt caccttacct cgatatactc aagtataatc tttggttacg gttcctagca
    12661 ctgtaaggta aaataaacca gcttttctcc cttcggggag attttttttg tttcactgaa
    12721 agtttcgtac gatcttcgcc tcgtcgccta gtctataaac gatttatcta gcaagaatca
    12781 tgatgctaag ggcgtcaaaa atccgtatga aaatagggaa atgacacagt gttcgatgag
    12841 cacaaggagt ttcatctttt tcactaggat tttagcccgg actcaaatca gctctctgac
    12901 ttcagagggc ttttttattg aggttttatc ggtaacaatt ttggagacta caaaaacctc
    12961 aaacggtatc agctaattac accataaagg tgcgcagtta ctcggctttt caagccgagt
    13021 agttgtatgc aagcccccta gaagagccca ctctttacaa agtaaagtat agtatgttat
    13081 actttacatg gaagtagtca ctgaattcca gttagaaatt actttgtaac tacgttttga
    13141 ggaggagtaa aatgctttcc tacgttcgat attacccact agcgatagct aaattaatgt
    13201 gtctgtgctc tcctaaaatc tgctgattta ttactgacta atacaggagt ttttttttat
    13261 gggacagaca atcatatctg ctattggtgt ttatatttcc accagtatcg attatttaat
    13321 tattttaatt attttatttg cacagctatc acagaataaa cagaaatggc atatttatgc
    13381 ggggcaatat ctaggcacag gcttacttgt aggggcgagt ttagttgctg cttatgtcgt
    13441 taatttcgtg cctgaagaat ggatggttgg attgcttggt ttaatcccta tctatttagg
    13501 gattcgcttt gcaattgttg gagaagatgc ggaagaagaa gaggaagaaa ttattgaaag
    13561 attagaacaa agcaaggcaa atcaactgtt ttggacagtt acattgctga caattgcgtc
    13621 tggcggagat aatttaggta tctatatacc ttattttgct tcgttagatt ggtcacagac
    13681 cctcgtggcc ttgcttgtgt ttgtaatcgg cataattatc ttttgcgaga ttagtcgggt
    13741 gttatcttct attccgttaa tattcgagac aattgaaaaa tacgagcgaa tcattgtgcc
    13801 cttagtattc attctacttg gactatacat catgtatgaa aatggcacga tagagacttt
    13861 tctgatcgtg tagatttttt tgtttcacta ggattttagt ccgagctcaa atcagctctc
    13921 tgattttcag agggcttttt cattgagtat aaatggacaa tcttaaagtt actctattgt
    13981 agagtggctt ttgatttgat taggagattc ttataaatat agtaaaatga aataagaata
    14041 ggacaaatcg atcaggacag tcaaatcgat ttctaaaaat gttttagaag tagaggtgta
    14101 ctattctagt ttcaatttga tatataaatg aaaaccttag ctgtttggcc aaggttcatt
    14161 tcttctatgc aagttcttct cttttcttat ctgggttcca gatgaagctt gcgataaagc
    14221 taaagatgat ggttaggata gcgagaataa tagcaaggat gagggcaggg atgcggataa
    14281 accaccagag tggatttggt tttttatcat tgtgccattg tttcgtttct tcgtccagac
    14341 gttggaattc tgtttgaata cgattggcga ctgtttcaat gccttcatca ttcattttct
    14401 tgatatctga gatatcgatt ggatttccaa agttcatatc gacacgttca cggctaatca
    14461 agcccttcaa agtcatggga ccggtgtagg taaccggcat gatacggacc ttggccattt
    14521 tggcaatcag tgctgcgccc cccttgacat cgtttgagtg gcggctacca cttggaaaca
    14581 tgatgagaga gcggtcactt tttttgagaa cgttgatagg atatttgatg gctgaggcgc
    14641 tgggattttc acggtcgatg ggaaaggcgc cacacatacg aatccaccaa ccaaagatac
    14701 ggttggtaaa gagttctttt tttgccataa agatgaactg ttttggcttg gtcgcaaagg
    14761 ccatataaac aggatcccac caggtacggt gaggcgcaac taaaatataa ttttcatctt
    14821 gattaggaat tttatcagta ttatgatagt gagcattgcc attgatggac cataagagca
    14881 atacaactaa tccacgcaaa taagtataaa acatgcgatc tccttcgatt gttttcttgt
    14941 tattattata ccttatcaaa ggagggctgg caaacttttc ccttgactag atgcatattt
    15001 gggatgaaat tagaattctg ttaaaaaaaa tgatataata gaatttatgg ataaaaataa
    15061 gattatggga ttaacccaaa gagaaatcaa ggaaagacag gctgagggtt tggtcaatga
    15121 ctttaccgca tcagccagta ccagcacttg gcaaatcgtt aaacgaaatg tctttaccct
    15181 ttttaacgct ttgaactttg ccattgcttt ggcccttgcc tttgtgcagg cttggagcaa
    15241 tctggtcttc tttgctgtta tctgctttaa cgctttttct gggattgtga ccgagctacg
    15301 agccaaacac atggtggaca agctcaatct catgaccaag gaaaaggtca aaaccatccg
    15361 tgatggtcag gaagttgctc ttaatcctga agaattagtg ctaggagatg tcattcgttt
    15421 gtctgcagga gagcagattc ctagtgatgc cttggttttg gaaggctttg cggaagtcaa
    15481 tgaagccatg ttaacgggag aaagtgattt ggtgcaaaag gaagttgacg gcttactttt
    15541 gtcaggaagt ttcctagcca gtgggtcagt tttatctcaa gttcaccatg tcggtgcaga
    15601 caactatgct gccaaactca tgcttgaggc taagaccgtt aaacccatca actcccgtat
    15661 catgaaatcg ctggacaagt tggctggttt tactgggaag attatcattc cctttggtct
    15721 ggctctcttg ctggaagcct tgcttttaaa aggcctgcct ctcaagtcat ccgttgtaaa
    15781 ctcgtcgaca gctcttttgg gaatgttgcc taagggaatt gcccttttga ccattacttc
    15841 gctcttgact gcagtgatta agttgggctt gaaaaaggtc ttggtgcagg agatgtactc
    15901 tgttgagacc ttggcgcgcg tggatatgct ctgtctggac aagacgggta ccatcaccca
    15961 aggaaagatg caggtggagg ctgttcttcc actgacggaa acttatggtg aagaggctgt
    16021 tgccagcatc ctgaccagct atatggccca tagtgaggat aaaaatccaa cagctcaagc
    16081 cattcgccag agattccaag gtcaagtagt ctatcctatg ctctctaatc ttcccttctc
    16141 cagcgaccgc aagtggggag ccatggagtt agaaggtttg ggaatagttt tcttaggggc
    16201 acctgagatg ttgctggatt ctgaggtccc agaagccaga gaggccttgg agagaggatc
    16261 acgtgtcttg gtcttagctc tcagtcagga gaaattagac catcacaaac cacagaaacc
    16321 atctgatatt caggctctag ccttgctgga aatcttggat cctattcgag agggagcggc
    16381 agagacgctg aactatctcc gttctcagga agtggggctc aagattatct ctggtgacaa
    16441 tccagttacg gtatccagca ttgcccagaa ggctggtttt gcggactatc acagctatgt
    16501 cgattgttca aaaatcacgg atgaggaatt gattgctctg gcggaggaga cagcgatttt
    16561 cggacgtgtt tcccctcatc aaaagaaact cattatccaa acgctgaaaa aagcgggtca
    16621 tacaacagct atgactgggg atggagttaa tgatatcctg gctcttcgtg aggcggattg
    16681 ttctatcgta atggcggagg gagacccggc aacccgtcag attgccaacc tggttctctt
    16741 gaactcagac tttaatgatg ttcctgagat tctttttgaa ggtcgtcgtg tggtcaataa
    16801 cattgcccac atcgctccga ttttcttgat aaagaccatc tattccttcc tgttagcagt
    16861 catctgtatt gccagtgctt tactaggtcg gtcagagtgg attttgattt tccccttcat
    16921 tccgatccag attaccatga ttgaccagtt tgtggaaggt ttcccaccat tcgttctgac
    16981 ttttgagcga aatatcaaac ctgttgagcc aaatttcctc agaaaatcca tgcttcgtgc
    17041 cctaccaagt gccctcatgg tcgtgtttag cgttcttttt gtgaaaatct ttggaacgag
    17101 tcaaggttgg tctgagttag aaatctcaac tctcctctat tatctcttgg ggtcaattgg
    17161 tttcttatcc gtatttagag cctgcatgcc attcactcta tggcgagtcc tcttgattgt
    17221 ctggtcagta ggaggcttcc tagccacagc tctcttccca agaatccaaa aactgcttga
    17281 aatttcaacc ttgacagaac aaacgttgcc tgtttatggt gtcatgatgt tggtctttac
    17341 agtgattttc atcctgacta gtcgctatca agctagaaaa taaagaaaga ctgcaatctg
    17401 tggattgcag tttttttagg tacaagattg ccagccgaaa tgtggtataa taagaggtaa
    17461 tagagttttg gaaagtgaga gaagatgatt tcaaagagat tagaattggt agcttccttt
    17521 gtgtcacagg gggctatttt actagatgtg ggaagtgacc atgcttatct gcctatcgag
    17581 ttggttgaga gaggccaaat caaaagcgct attgcaggtg aggtggtgga aggtccctat
    17641 cagtctgcgg ttaaaaatgt tgaggctcac ggcctaaagg agaaaatcca agtccgttta
    17701 gccaatggct tggcagcttt tgaagagact gaccaagtgt ctgtcattac cattgctggc
    17761 atgggtggtc gtttgattgc taggatttta gaagaaggtt tggggaagtt agctaatgta
    17821 gagcgtttga tcctccagcc caataatcgt gaagacgact tgcgtatctg gctacaggat
    17881 catggattcc agattgtagc agaaagcatc ttagaagaag ctggaaagtt ttatgagatt
    17941 ttggtggtgg aagcaggaca aatgaagcta tcagccagtg atgttcgctt tggtcccttc
    18001 ttgtccaaag aagtcagtcc agtatttgtc caaaaatggc aaaaagaagc tgagaagcta
    18061 gagttcgctc tcggacaaat cccagaaaaa aatctggaag aacgtcaagt tctagtagat
    18121 aagattcaag ctatcaagga ggtgctccat gttagcaagt gaagtgattc atgcttatga
    18181 agccttttgc cctcaggaat tttctatgga gggagacagc cgtggtctgc aaattggcac
    18241 tttagacaag ggtatccaaa gggtcatggt tgccctcgat attcgtgaag agacagtggc
    18301 agaggccatt gaaaagggtg tggacttgat tatcgtcaag cacgcgccta tctttcgtcc
    18361 tatcaaggac ttgcttgcca gccgtccgca aaatcagatt tacatcgacc tgattaagca
    18421 tgacatcgca gtttatgtca gccataccaa tattgatatc gttgaaaatg ggctcaatga
    18481 ctggttttgt cagatgctag gaatcgagga gacgacttat ctgcaggaaa caggtccaga
    18541 acgtggaatt ggacgtattg ggaatattca gcctcagaca ttttgggaat tggcccaaca
    18601 ggtcaagcaa gtctttgacc tagatagcct tcgaatggtg cattatcaag agaatgattt
    18661 gcagaagcct atttcaagag tagcaatttg tggtggaagc gggcagtctt tctataagga
    18721 tgctttggca aagggggcag atgtctatat cactggtgat atctactacc atactgctca
    18781 ggatatgctg tctgatggct tgttagcatt ggatccaggt cactatatcg aagtgctttt
    18841 tgtggaaaaa atcgcagcac tccttactca atggaaagag aaaaaaggct gggaactaga
    18901 gattttacct agtcaagcat cgaccaatcc tttccgtcat atctagttag aaagtgaaga
    18961 caatgaaaaa agttgccatt attggagcag gaattgtggg agcaacagct gcctactacc
    19021 tctcgagaga aagtgaccta gaggtgaccg tttttgacca tgagcaaggt caagccacca
    19081 aggccgcagc aggaattatc agtccttggt tttccaaacg ccgtaataaa gcctggtaca
    19141 agatggcgcg cttgggggct gatttttatg tggatttatt agctgattta gagaaatcag
    19201 gacaaaaaat cgacttttac cagcgttcgg gagtctttct cttgaaaaag gatgaatcca
    19261 agttggaaga actttatcaa ctggccctcc agcgcagaga agaatctccc ttgatagggc
    19321 aattagccat tctggaccaa gcctcagcta atgaattatt ccctggtttg cagggatttg
    19381 accgcctgct ctatgcttct ggtggagcga gagtagatgg ccaactcttg gtaactcgtc
    19441 tgctagaagc cagtcatgtc aagctggtca aagaaaaagt gactctgaca ccgttagcat
    19501 caggctacca gattggtgaa gaggagtttg agcaggttat tttggcgacg ggagcttggt
    19561 tgggggacat gttagaaccc ttgggttatg aagtagatgt tcgtcctcaa aaaggacaac
    19621 tacgagatta tcagctggtc caagacatgg aagcttaccc tgttgtcatg ccagaagggg
    19681 agtgggattt gattcctttt gcaggtggga aattgtcctt aggcgctacc cacgaaaatg
    19741 acatgggatt tgatttgacg gtagatgaaa ccttgctcca acaaatggag gaggccacct
    19801 tgactcacta tctgattttg gctgaagcta cttcaaaatc tgagcgtgtt ggaatccgtg
    19861 cctacaccag tgatttctct cctttctttg ggcaggtgcc tgacttaact ggtgtctatg
    19921 cagccagtgg actaggttca tcaggcctca caactggtcc tattattggt taccatttag
    19981 ctcaactgat ccaagacaag gagttgacct tggaccctga aaactaccca attgaaaact
    20041 atgtcaaacg agtaaaaagc gaataatact caatgaaaat caaagaacaa actaggaaac
    20101 tagccgcggg ttactcaaag cactgctttg aggttgtgga tagaactgac gaagtcagct
    20161 caaaacactg ttttgaggtt gtagatagaa ctgacgaagt cagtaaccat acccatggca
    20221 aggcgacgtt gacgtggttt gaattggatt ttcgaagagt ataagcattt tactgaaatt
    20281 ttatcaggta gtttaggatg gcaaatgaca ttccctgtca aaaatggtaa aataagaaaa
    20341 aataatctga gaatcgagga aaaaagatgc aagaaaagat tttggtaact ggtggtgccg
    20401 gttttattgg aacccacact gttattgaat tgatccaagc aggccatcaa gttgttgtgg
    20461 tggataatct tgtcaatagc aatcgtaaga gtttagaagt tgttgaaaga atcacaggag
    20521 ttgagattcc tttctatgag gcagatattc gtgacacagc taccctcaga gatattttca
    20581 agcaggaaga accgactggt gtcattcact ttgctggttt gaaggctgtt ggcgaatcaa
    20641 cacgtatccc tcttgcctac tatgacaaca atatcgctgg aactgtcagc cttttgaaag
    20701 ccatagaaga aaacaactgt aaaaacatca tcttcagttc ttctgcgaca gtttacgggg
    20761 atccgcacac agtgcccatc ttggaagatt tcccactttc agtgaccaac ccatacggtc
    20821 gtactaagct catgctagag gaaattttga ctgatattta caaagcagac tcagaatgga
    20881 atgttgtctt gcttcgttac tttaacccaa tcggagccca tgagagtggt gatttgggag
    20941 aaaatccaaa cggtattcca aacaatctct tgccatatgt gactcaagta gccgttggaa
    21001 aattagagca agtgcaagtg tttggagacg attacgatac ggaagatgga acaggtgttc
    21061 gtgactatat ccacgttgtc gatttggcta agggtcacgt tgcagctttg aaaaaaatcc
    21121 aaaaaggttc aggactaaac gtttataacc ttggaactgg taaaggttac tcagttcttg
    21181 aaattatcca aaacatggaa aaagcggtgg gacgtcctat tccttaccgt atcgtagaac
    21241 gtcgcccagg tgatatcgct gcctgctact cagacccagc aaaagctaaa gcagaactcg
    21301 gttgggaagc agaactcgac atcacccaaa tgtgtgaaga cgcatggcgt tggcaaagca
    21361 agcatccaaa tggatttgaa gactaagatg atgatttcaa tcatcgtccc ttgtttaaac
    21421 gaagaggaag tacttcctct tttttatcag gctctggaag ctttacttcc agatttggaa
    21481 acagaaatcg agtatgtctt tgtcgatgat ggatcaagtg atgggacctt ggaactctta
    21541 aaggcctatc gggagcaaaa tccggcagtc cattatattt ctttctctcg aaattttggc
    21601 aaagaagcag ccctttatgc aggcttgcaa tatgcgacag gagatttggt ggtggtgatg
    21661 gatgcagacc tccaagatcc tcctagtatg ttgtttgaga tgaaaaatgt actagacaaa
    21721 aatgtagact tggactgcgt tgggacacgg agaactagtc gggagggaga acccttcttt
    21781 cgcagtttct gtgctgttct cttttatcgc ctcatgcaaa aaatcagccc agtggctctg
    21841 ccgtcgggtg tccgtgattt tcgtatgatg agaaggtctg tagtcgatgc cattttaagc
    21901 ttgaccgagt ccaatcgttt ttcaaagggg ctcttcgcct gggtgggttt caaaacctac
    21961 tatttggact atccaaatgt cgaaaggcag gctggcaaga ccagttggag ttttaggaaa
    22021 ctctttttct actccattga agggattatt aatttttcag attttccctt gattatagcc
    22081 tttgtagctg gtctcctatc ttgttttctt tctctgctga tgaccttttt tgttgtggtt
    22141 cggaccctca ttttgggcaa tccgacatct ggttggacct ctctgatggc tgttattctc
    22201 tttcttggag gcattcaact cttgaccatt gggattctcg gcaagtatat cagtaagatt
    22261 tatttagaga ctaaaaaaag accactttat cttatcaaag aaaaaagtga tgataggcta
    22321 aaaaagatag aatttatctg acatagtcac tttttgttat ttgtaattct tttagttcgg
    22381 agtttgggtg atttttaaaa gaattaggga tttgaaatga tttaaaaaat ctatgtagac
    22441 taaatttaaa ttgtagtgac ttaataaata aaaaatttag gagtattatg ttatgctaag
    22501 taaagaggat tatactgaag aaatcgggct aataaagaaa caaaattatg tagaggctga
    22561 attgtatcct atagttgctg atataattaa gccaacttta aaagatagtt tatcaaaaag
    22621 atatgtcttc ggaagacaaa gaaggggttt gggacaaatt tattatggtc taagtaattt
    22681 tcctgatata gttattttag ataagactta tgaaaacaaa tctaggaaaa gtataaaaat
    22741 tgaagaatgg aagaaacttc gaggatgcgt ggaagttaag aatttaaatt atagtttaat
    22801 tacagaggaa aaaatcaaat caaccatatc gaacagtttt gaacatataa ctggagagat
    22861 ggaacaacta actggagaga tgggacaact tattggagac cttttatggt ataaaaaagt
    22921 aatttataca aatggaattg aatggagatt tctaagttta gatgacaagg aagagataga
    22981 taatacaatt gttgaagtag ttaacaaaag aatagaaaca gaagaagcgg gaaattcttt
    23041 tgattggtgg aagaatatta aagatttatc gttcaattat acggatatat gcctatctaa
    23101 agattgtaga caagagtgga atgaatttgt aaaaagggta aaggaaatag aatggtagaa
    23161 gtctattctc attgagaaat ttagatttta agttacagta agatttattt agagactaaa
    23221 aaaagaccac tttatcttat caaagaaaaa agtgaccttc ctgattttac agaaaaaaat
    23281 aaagtgaaaa gactataatt ttacatggaa atgtgctaaa ctagagggag tggattatcg
    23341 ccattgattt aggcttcctg gtttccaatc agggcgcgag ttgggcaatt tttaacagcc
    23401 tctaagacat cctgactagg agaaatttct ttttccagtt ggtcagggtc atcgtaaaaa
    23461 cgcacgattc cattatcgtg gtaatcaaat aaatcagaat aagtttggca aagcccacag
    23521 gcgatacatc gttcaggtat aagtgtgatt ttcatgttca tatttatatt gtaataagaa
    23581 aagtaaaaaa aaacaaggag taaggtatgg caaaagaacc gtggcaagaa gatatctatg
    23641 atcaagaaga atcaagagca gagcgtcggc atcgaaacca cggaggggct gataggatgg
    23701 ctaatcgtat tttgacgatc ctagctagta ttttctttgt aattgtggtg gtgatggtca
    23761 tcgttctcat ctatctatca tcggggggaa gtaatcgcac agcagcctta aaagactttc
    23821 atgattctga tgcaagtgta gtacaaatct catcttcaag cagttctcag cctgagcaga
    23881 gttcagagcc agaatctact tctagtagtt cagaagaagc tgctaatcct gaaggaacga
    23941 ttaaagttct cgcaggagaa ggggaagcag ctattgccgc tcgtgcagga atctccattg
    24001 ctcagttaga ggccttgaat cctgggcaca tggctacagg atcttggttt gctaatccag
    24061 gtgatgttat aaaaataaaa taggagccga tatgaaaaca attcaaattg ctattgatgg
    24121 tcctgcttcc agcggtaaga gtacggtcgc aaagattatt gctaaggatt ttggattcac
    24181 ctaccttgat acaggagcta tgtatcgtgc agcgacctat atggctctta agaaccaatt
    24241 aggagttgaa gaagtcgaag cccttctagc cttgttggac cagcatccaa tcagctttgg
    24301 acgttcagaa actggagacc agcttgtttt tgtaggagat gtggatatta cccatcctat
    24361 ccgtgaaaat gaagtgacca atcatgtttc tgctattgca gcaattcctg aagtgcgtga
    24421 gaaactggtt tctctccaac aagaaattgc ccagcaaggc gggattgtca tggatggtcg
    24481 cgatattgga actgttgtat tgccacaagc agaattgaaa attttcctag tagcttctgt
    24541 tgatgagaga gcagagcgtc gttacaagga aaatattgcc aagggaattg aaacagactt
    24601 tgaaacccta aaaaaggaaa ttgctgcgcg tgactacaag gatagtcatc gtgagacttc
    24661 tcctctcaaa caagcagagg atgctgtcta ccttgataca actggtttga acattcaaga
    24721 agtagttgaa aaaatcaaag cagaagctga aaaaagaatg taaatgtaga aaagccgata
    24781 gattgatatc ggtttttttc taaatttgtc aaaatgctga ttttagggta taatagttgc
    24841 tgttcgagaa attttgattt tcaaagaata gtgaatgatg ataaggagaa accatgaaca
    24901 atttaccaaa ttgtccaaaa tgtaactcag agtatgtcta cgaagacggt gccctactgg
    24961 tttgcccaga gtgtgctcat gagtggaatc ctgctgaagt tgcagaagta gaagaaggtc
    25021 ttgtcgctat cgatgccaac ggaaataaat tggctgatgg tgatacagta actctcatca
    25081 aggacttgaa agtaaaaggt gcgccaaaag atttgaaaca agggacgcgc gtgaaaaata
    25141 tccgcatcgt agaaggcgac cacaatatcg actgtaagat tgatggtttt ggtgccatga
    25201 aacttaaatc agagtttgtg aggaagattt aagcatgtca aaacactata aacttgtatt
    25261 ttatagccgt atcttcttgt ttctagcggc ttttacggga gtttatcttg aaattactaa
    25321 gcatggtggt tttgggatgc ttctctatta cacggttctg tccaacctct tggtaactat
    25381 ttttaccctt tatcttctaa aggttatgag ccgtgtaggt gaaaattggc aaaggccaag
    25441 tctcttgcgc ttaaaaggtg gggtcaccat gagtatcatg attacctgtg tgatttacca
    25501 tttcctcttg gcgcccattg cgactaattt ctatacccta gaaaatttcc tttgccacta
    25561 tatcgttccc atctggtttt tagcggatac cctctttttt gacaaacagg gtcaatacaa
    25621 gatttgggat ccagcagtgt ggaccatttt accctttctg tatatgatgt ttgctctttt
    25681 taatggcttg gttctaaaac tcaatattcc aaatgccaag gataatcctt tcccttactt
    25741 ctttttgaat gtgaacaagg gttggaatgt tgtgtttaag tggtgtctga ttatctttgt
    25801 tgcctatatg gtagcaggat ttattttcta ctttatcaag caaatcaaga gaaagtcatc
    25861 ctaatactct tcgaaaatct cttcaaacca cgtcagtttc catctgcaac ctcaaaacac
    25921 tgttttgaac aacctgcggc tagcttccta gtttgctctt tgattttcat tgagtataag
    25981 atacaaggga ttcattttcg aatttaagaa ggagtctaca aaccaatgag gcttcttctt
    26041 ttcttgctta tttgataact atcaaaaaag tagaagatta agagaaatat agaaagagat
    26101 ttcatgaaac aatttttaga acgggccagc attttggctc tctccctcgt tttgattacc
    26161 tccttttcca tttcgagtgc cctaccagcc atgtttgact attatcaggg ttattctaag
    26221 gaacaaattg agctcttggt gagcttgcct tcctttggaa tcatgatgat gttactgcta
    26281 aatggtttct tagaaaaaat atttcctgag cgcttacaga ttagtttggg cttgctgatt
    26341 ttatcattga gcggtacagc tcccttctgg taccaagcct atccctttgt ctttggaaca
    26401 cggcttctct ttggtttggg tcttgggatg atcaatgcca aggccatttc tattatcagt
    26461 gaacgctacc aaggaaaaag gcgaattcag atgttagggc tacgcgcttc tgcagaggtc
    26521 gttggagctt ctctcattac cttggccgtc ggtcagttgt tggcctttgg ttggacagct
    26581 atctttctag cctatagtgc tggatttttg gtgctgcccc tttatctgct ctttgtccct
    26641 tatggaaaat caaagaaaga agtcaagaaa agagcgaagg aagcaagtcg tttaactcga
    26701 gaaatgaaag gcttgatttt taccttagct atcgaagcgg cagttgtagt ttgtaccaat
    26761 acagctatta ccatccgtat tccaagtttg atggtggaaa gaggattggg ggatgcccag
    26821 ttatctagtt ttgttcttag tatcatgcag ttgatcggga ttgtggctgg ggtgagtttt
    26881 tctttcttga tttctatctt taaagagaaa ctgctcctct ggtctggtat tacctttggc
    26941 ttggggcaaa tcgtgattgc cttgtcttca tccttgtggg tggtagtagc aggaagtgtt
    27001 ctggctggat ttgcctatag tgtagtcttg acgacggtct ttcaacttgt ctctgaacga
    27061 attccagcta aactcctcaa tcaagcaact tcatttgctg tattaggctg tagtttcgga
    27121 gcctttacga ccccatttgt tctaggtgca attggcttac taactcacaa tgggatgttg
    27181 gtctttagta tcttaggagg ttggttgatt gtaatctcta tctttgtcat gtacctactt
    27241 cagaagagag cttaggattg attcctaagt ttttcttttg atactcaatg aaaatcaaag
    27301 agcatagttg attgagtttg gaatagtacg ctgtagctgc taaaatattt ctagaaatta
    27361 atttgacttt tctaatagag ttattcatat cttatttcaa tctactatag aaagctagcc
    27421 gcaggttgct caaaatagtg ttttgaggtt gcagatggaa actgacgtgg tttgaagaga
    27481 ttttcgaaga gtatgagatt tttataccca tacaatattt gttttaggtc cttgtttaca
    27541 gactaatttc ttgataaaat agaggttatg acgagatata aagcaactat ttcctatgat
    27601 ggttatgcct ttgctggctt tcagcgccag cctcatgcgc gtagcgttca ggaagaaatt
    27661 gaaaaaacct tgaccagatt aaataaaggg caagccatta ctgttcacgg tgctggtagg
    27721 acagatagtg gggttcatgc cctgggacag gtcattcatt ttgacctgcc ttatcagatg
    27781 gatgaggaga aactccgttt tgccttggat acccagtctc ctgaagatat tgatgtgatt
    27841 tcgattgagc ttgtggcaga tgattttcat tgccgttatg ccaagcatag caagacctat
    27901 gagtttactg tggatagagg acgtcccaaa aatccgatgc gccgtcacta tgccacccac
    27961 tttccctacc cactcgatgt ggaacgaatg cagattgcaa tcaaaaagct agagggaacc
    28021 catgatttta ccggttttac agcctctggg actagtgtag aggataaggt tcgcaccatc
    28081 acagaagcta gtttaatagt cgatgagaca ggacaatttt tgacctttac cttttcagga
    28141 aatggtttct tgtataaaca gattcgcaat atggtgggga ctcttctcaa aatcggtaac
    28201 aaccgcatgc cagtagagca gattgatctc atcttggaga agaaggacag gcaacttgca
    28261 ggtcccactg cagcaccaaa tggtttgtat ttaaaggaga ttcgttatga agaataatcg
    28321 tattttagca ctttctggaa atgatatttt tagtggtggt ggactgtcag ctgatttggc
    28381 tacctatacc ttgaacggct tgcatgggtt tgtagcagtg acttgtttga cagccttgac
    28441 agaaaaagga tttgaagtct ttccaactga tgataccatt tttcaacatg aattagatag
    28501 cttgcgtgat gtggaatttg ggggaattaa gattggtctt ctccctactg tcagtgtggc
    28561 tgagaaggcc ttggacttta tcaaacaacg cccaggagta cctgtggtgt tggatcctgt
    28621 cttggtctgc aaggaaacgc atgatgtagc tgtcagtgag ctctgccaag agttgattcg
    28681 ctttttccct tatgtcagtg tgattacgcc taatctccca gaagcagaat tattatccgg
    28741 tcaggaaatt aaaaccttgg aagacatgaa aactgcagcg cagaaattgc atgatttagg
    28801 agcgccagca gtcattatca agggaggcaa tcgtcttagt caggacaagg ctgtggatgt
    28861 cttttatgat ggacagacct ttactatcct agaaaatcca gttatccaag gccaaaatgc
    28921 tggtgcaggt tgtacctttg cctctagcat tgccagtcac ttgattaaag gtgataaact
    28981 tttgccagca gtagaaagct ctaaggcttt cgtttatcgt gctattgcac aagcagatca
    29041 gtatggagta agacaatatg aagcaaacaa aaacaactaa aatcgccctt gtatccctat
    29101 taaccgccct ttctgtggtt ctaggttatt tcttaaaaat cccaacacct acaggaattc
    29161 taactctttt agatgctggt gtcttctttg cggcctttta ctttggtagt cgtgaaggag
    29221 cggtagtcgg aggactagca agtttcttga ttgacctctt atcaggctac cctcagtgga
    29281 tgttctttag cttggtcaac catggcttgc agggattttt cgcaggattt aaaggaaaaa
    29341 gtcagtggtt aggccttatt ttagcaacta ttgccatggt aggaggctac gccttgggtt
    29401 ctactttgat gaatggctgg gcagcagccc tcccagaaat tctaccaaat ttcatgcaaa
    29461 atatggtagg gatgattgta ggatttattc ttagtcaaag tatcaagaag attaagtaat
    29521 actcttcgaa aatctcttca aaccacgtca gcttccatct gcaacctcaa aacactgttt
    29581 tgagcagcct gaggctagct ttctagtttg cactttgatt ttcattgagt ataaagaggt
    29641 tgagtaaaaa gtatttcaaa taagaaaaac gcatagtatc aggtgttgaa tgaactgccc
    29701 cccaaaaagt tagacagaaa aaatctaact ttttggggtg tttttattat gaaattaa
//
LOCUS       DAVAZV010000023        28647 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVAZV010000023 DAVAZV010000000
VERSION     DAVAZV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28647
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.023"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(512..2239)
                     /gene="ezrA"
                     /locus_tag="VQT46_001005"
     CDS             complement(512..2239)
                     /gene="ezrA"
                     /locus_tag="VQT46_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET2371047.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2321..4267)
                     /gene="gyrB"
                     /locus_tag="VQT46_001006"
     CDS             complement(2321..4267)
                     /gene="gyrB"
                     /locus_tag="VQT46_001006"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET2371048.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFIPDPKIFTETTTFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4282..4845)
                     /locus_tag="VQT46_001007"
     CDS             complement(4282..4845)
                     /locus_tag="VQT46_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2371049.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEDILNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4930..5484)
                     /locus_tag="VQT46_001008"
     CDS             complement(4930..5484)
                     /locus_tag="VQT46_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET2371050.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5495..6718)
                     /locus_tag="VQT46_001009"
     CDS             complement(5495..6718)
                     /locus_tag="VQT46_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2371051.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6755..9205)
                     /locus_tag="VQT46_001010"
     CDS             complement(6755..9205)
                     /locus_tag="VQT46_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET2371052.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIHISSTKSGRTLLSSL
                     LPESCQAMGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIIGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9404..10333)
                     /locus_tag="VQT46_001011"
     CDS             complement(9404..10333)
                     /locus_tag="VQT46_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2371053.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELLVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10473..10760
                     /locus_tag="VQT46_001012"
     CDS             10473..10760
                     /locus_tag="VQT46_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET2371054.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10794..12128)
                     /gene="ciaH"
                     /locus_tag="VQT46_001013"
     CDS             complement(10794..12128)
                     /gene="ciaH"
                     /locus_tag="VQT46_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET2371055.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12118..12792)
                     /gene="ciaR"
                     /locus_tag="VQT46_001014"
     CDS             complement(12118..12792)
                     /gene="ciaR"
                     /locus_tag="VQT46_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET2371056.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12901..15447)
                     /locus_tag="VQT46_001015"
     CDS             complement(12901..15447)
                     /locus_tag="VQT46_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET2371057.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHIAYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15571..16011)
                     /locus_tag="VQT46_001016"
     CDS             complement(15571..16011)
                     /locus_tag="VQT46_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET2371058.1"
                     /translation="MIPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQSVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(15986..16855)
                     /locus_tag="VQT46_001017"
     CDS             complement(15986..16855)
                     /locus_tag="VQT46_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET2371059.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDLESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16897..17625)
                     /locus_tag="VQT46_001018"
     CDS             complement(16897..17625)
                     /locus_tag="VQT46_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371060.1"
                     /translation="MELFKTWKKNMVLYGLKSQIGTVYRNNDRTTSFYDVGNFLYLAG
                     ELDSRFWEDFVRKYGLDYKIIISENTNWQDFLHRKVGLNSFTRYSFKDKANFQVEFLN
                     NLVTHLEEGYNIVPIDNHIYNCFSTEEWSQDLQGDFESYQDFVLKGGFGFVILKNNEL
                     IAGISSGLVYRKAVEVEVATRPNEQGNGFAKKLGAAMILESLNRDMFPLWDAHNEASK
                     KVAEFLGYELSEPYEAFELEEILI"
     gene            complement(17633..18112)
                     /locus_tag="VQT46_001019"
     CDS             complement(17633..18112)
                     /locus_tag="VQT46_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2371061.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELTNFMVDHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVK"
     gene            complement(18123..18821)
                     /locus_tag="VQT46_001020"
     CDS             complement(18123..18821)
                     /locus_tag="VQT46_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET2371062.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18814..19080)
                     /locus_tag="VQT46_001021"
     CDS             complement(18814..19080)
                     /locus_tag="VQT46_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET2371063.1"
                     /translation="MKNVELKEKNMTFEEILPGLKAKRKYVRTGWGGAENYVQLFDTI
                     EQNGLALEMTPYFLINVSGEGEGFSMWSPTVCDVLATDWVEVHD"
     gene            complement(19146..20072)
                     /locus_tag="VQT46_001022"
     CDS             complement(19146..20072)
                     /locus_tag="VQT46_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET2371064.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFNLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20147..20962)
                     /locus_tag="VQT46_001023"
     CDS             complement(20147..20962)
                     /locus_tag="VQT46_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371065.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(20966..21286)
                     /locus_tag="VQT46_001024"
     CDS             complement(20966..21286)
                     /locus_tag="VQT46_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2371066.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLTKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(21583..21663)
                     /locus_tag="VQT46_001025"
                     /pseudo
     CDS             complement(21583..21663)
                     /locus_tag="VQT46_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(21707..23704)
                     /gene="metG"
                     /locus_tag="VQT46_001026"
     CDS             complement(21707..23704)
                     /gene="metG"
                     /locus_tag="VQT46_001026"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET2371067.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEYDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23828..25087)
                     /locus_tag="VQT46_001027"
     CDS             complement(23828..25087)
                     /locus_tag="VQT46_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371068.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKKSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(25089..25790)
                     /locus_tag="VQT46_001028"
     CDS             complement(25089..25790)
                     /locus_tag="VQT46_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371069.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25774..26973)
                     /locus_tag="VQT46_001029"
     CDS             complement(25774..26973)
                     /locus_tag="VQT46_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET2371070.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILIPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            27259..28605
                     /gene="gor"
                     /locus_tag="VQT46_001030"
     CDS             27259..28605
                     /gene="gor"
                     /locus_tag="VQT46_001030"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET2371071.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESIAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
BASE COUNT         8572 a         6299 c         5114 g         8662 t
ORIGIN      
        1 ttttagtcta gtataaatag cgagaaatat ctatcctatc ttctagaatg tcttccaaac
       61 gagaaaactc tcgtaaacaa agaggtttta gaggcctatt taccgtggac taaagttgta
      121 caagaaaagt gcaaataaga aatctccaga ttaggaacta tccgtgagtt ctctagtctg
      181 gagatttttc aatagacttc gttattggac ggttaccaag ttacttcaaa gtacagattt
      241 gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca aaaagcaaac
      301 taagaagcta gcctcaggct gtacttgagt acggtaaggc gacgctgacg tgatttgaag
      361 agattttcga agagtataaa acactgtttt gaagtggtgg ataaatcggc tgggtaaaaa
      421 ctcaatctca ggagaaaatg aagtaaatct ccccacaact atagaaaaag atttgattct
      481 gctcctcaca caataaaatc tttttctttt attaaaaacg aatcgtttca cgtgttttct
      541 catatgaggt aacaaagcga ttggttacac caggctctgc cacttccaat gcttgagaaa
      601 tcttgtcaaa tgaagcgtga taatcaaatt ctttttcaaa aatatctaaa gcttcgttaa
      661 atgcttcttg aatgcgttca tcaaatgagc gatagcggtt agaatattgc aagagttgct
      721 ctgtcaaagt tgcatattgt acaatattat aagtttccgt ttctaaagct tccatatcat
      781 tcgttgcaat ttcaagaact cgggtaacag attcaatgtt aatcattttt tgttctaact
      841 caaccattaa atcctcggta ttattgcttg ccgtaaagaa taacttcaag aaagtttgtg
      901 gaatacctgg cagattgcgt ttttccatgt atcgcttgat agtatggaga cgattgacat
      961 aaacattggc cttttgacgt gcattaatat catctttctc aatttgtgtc aggcgctcac
     1021 taactgaaat ttgctcatct tcaatatctt ttagttgagt ttgtaaatcc tcaagatttt
     1081 cttcaagaac tgaataagct tgggttggtt cttcttgatt tgaagttacc tcaacaatag
     1141 ctgcctcaaa actctctaat tctgtctgaa tacgacgaac atggcttgca gctgtctcag
     1201 gaagtaaata ggtcttgttc aaacgtgcaa tatcttctcc caataaagta ttattctctt
     1261 tcatatgttg aaggtaagtt ggaagagttg caagtagatt ttccactact ttctgagcag
     1321 caatttctcg agtaaaaata tcatacaagg cattgatttc ctcttgtgcc tgtccattct
     1381 catattcggc attatccaat tccaactgac gaatattctc ttggtttttc ttgaatgctt
     1441 cataaagcaa gtggaaacgc gcttcaatat ccgtttcaac aaaatgataa ttagcatcaa
     1501 ttagtttacg ataaccggct tccaaatcct gtaattgatc tggcaattct gtagaaagcg
     1561 tcgtaaccaa ggctggaaca cgatccacaa tatgacttaa ggccaaaatg tgattttctg
     1621 tattatccaa aatcactgcg gcttccacag ggtcacccga tgaattcaag gttacaaatt
     1681 gtgaaaattc agattggata ttttctaatt gtttttcaat ttcatccaag gcttgaccat
     1741 actgttctga attttcagca actctatgct gaagttcctc aaataaatcc aaagcatgaa
     1801 gaacacgacc actattttta gattcttgct tctctaagtc tgccaaagca ttgcgaattg
     1861 ccgcaatatc ttcttcaatc aaagtaattt gactctcaat ttggtcaatt tgatgactgg
     1921 ccttgagaaa acgaaatgaa tggttataac cttctgcttc aaagagatta ttttcaatat
     1981 cggcaaaaga gttgagagat aaatcgaccc atttttgatt ccattcacgg aaagccactt
     2041 gactttgtcc aatcaagtgc atatttttta cagcttctac ttcatcattt actggaagat
     2101 tgtatagttc ttcttttctt tcttctagcg cctctaatct cccctcgttt cgcttacgta
     2161 gaaagattgc cactacataa gccagaacta aaatgactgc aattgcaacc attaaataaa
     2221 ttagttgtcc attagacata tcaaactcct tttttacttg aaacaatcgt aacgattata
     2281 tcatattttt tagaccaagg gaactacttc tccctatttt ttagacatca agtgtactat
     2341 agacagcatt ttcttcgata aactcacgac gaggctctac tcgatccccc atcaacatat
     2401 caaagatttt atctgcttct gcagcatcat ctacagaaac tctagccatc aagcgatgtt
     2461 cgggatccat ggttgtttcc cacagctgat gatcgtccat ttcacctagc cccttataac
     2521 gctgaatagt cggtttggta cgaccttcac tataacgggc taaagcttct tggagtttga
     2581 tttcttgatc tgcacccggc tggatatatt ctttaatctc gcttccaacc ttgacaccat
     2641 agattggtgg ttgggcaata taaacataac cagcttctag gattggtttc atataacgat
     2701 aaatcaaggt taaaagaagg gtacgaatat gggctccatc gacatcggca tcggtcatca
     2761 aaacgagttt ttggtaacgg gctttcgaaa catcaaattc tgcgccaaat cctgttccca
     2821 tggctgtgaa aagactacga atttcttcgt tagctagaat cttatccata cttgcttttt
     2881 caacgttcaa aatcttaccg cgaattggaa ggatagcctg aaactcacgg ttacgaccag
     2941 atttggctga tccaccagct gagtctcctt cgacgatgaa gagttctgtt tcagcagggt
     3001 tattagaaga acagtctgct agtttccctg gaaggttgga aatttccaaa ccagattttt
     3061 tacgtgtgac ttcacgcgca cgcttggcag ccacacgagc cttggcagct aaaatccctt
     3121 tttccacgat acgtttggca atctgtggat tttccatgag gaaatcggag aaggcttcac
     3181 tgaagaggcg attggtaatc ttgaccactt cgctatttcc caatttggtc ttggtttgtc
     3241 cttcaaactg tggatttggg tgtttaactg agataactgc agttaatcct tcgcgaacat
     3301 cttcccctgt taaattatct tcattgtctt tcagtaactt attcttacga gcataatcat
     3361 tgataacacg agtcagtgcc gtacggaaac cttgttcatg cgttccacct tcatgggtat
     3421 gaatattatt ggcgaaactc atgacatttt catggtaacc tgttgtgtac tgcatggcta
     3481 cctcaactgt gatatcatcc atctcaccgt ctgtatagat tggtgtatca aagattacat
     3541 ccttgttctc gttgatatat tcaacgtaac tagcaatccc accttcataa tgataatgct
     3601 tggtttgttc caaaccttgg cgcttatcag tgatagaaat ttgaagaccg cgatttagaa
     3661 aggccaactc ttgaatccgt ttatttaatt tatcaaaatc aaaggttgtt gtttcagtaa
     3721 agatttttgg gtccggtatg aagtgaaccg ttgttccagt tctatctgta tccccaacca
     3781 cctcaaggtc tgcaacaaca tgaccacgac ggtattcttg gtaatgaatc ttaccgtttt
     3841 tatggacatg aacgtctaat tgagtggaaa gggcattaac tactgacgac cccaccccgt
     3901 gaagaccacc tgaaaccttg tatccaccac cgccgaactt tcctccagca tgaaggactg
     3961 taaagacggt ctcaacagca ggacggcctg ttttttcctg aatatcgact gggataccac
     4021 gcccatcatc cacaacagta atcgaatcat ctggctcaat aaaaacttga atatggctgg
     4081 caaatcctgc caaggcctcg tcaattgagt tatcaacaat ttcccagact agatggtgaa
     4141 gaccttcttt tgaggttgat ccaatgtaca tccctggacg catacgaaca gcctctaagc
     4201 cctctaaaac ttgaatttga ctggcatcat aatcctgtgc ctgcagattt ttgatttctt
     4261 ctgtcatctt attccttttt cttatatgtc taatacttgt cttaaattca cgatactggt
     4321 aaacaagtgg gtatcaagtc ctgcagcttg acctgcttcg atatcaatcg gccgatcacc
     4381 aatgacaaga ccagagctaa tctgatactt ttctcttaaa taaagcatgg attcgggatt
     4441 tggctttctc ttaaagcctg agctagaagt caccacttct gtaaaataag ctgctataga
     4501 ggttttttct aaaatttcca aaacctgatc atttcgatga gagaccaaaa aatgacggcc
     4561 accttgattt aaaatgtctt ccaataggtc agaaactcct tcaaataaaa tcgggtgttc
     4621 aagctctctg gcttcatttt ccttgtactt ttctaaaaaa ttctctaaat tgggagcgaa
     4681 tgtctcaatc gcaaaaggag tagaaacctt taaagcttga tagacactgt catggtcttg
     4741 tgtgatacca tacagtgcca atgtttcaac aaatgcagct gttgaagttt cataattatc
     4801 cagtaaagtt ccacctaaat cccagatgta atcgtgatat ttcataccct tcattatagc
     4861 atttttttat gaaaaaagcg atgatttccc tgagttttcc acataaaaaa cgagagaata
     4921 actcccgttt tactgatttt taccaaagac atctcgatag agcattcctg ttcgtaaact
     4981 ctctgcgtcc cctcctagtt gctccaccaa ctcgtaggca aaggcaaggg ctgttgaagg
     5041 accccgactg gttgtcaact gaccatctac cactactgtt tccttgacgt agtgaccatc
     5101 aaggatttgc tcttgaacgc cgtcataaca agtgtatcgc ttatttttca atatctctgc
     5161 ttgattgagg gcaattggtg ccgcacaaat ggctgctagt ttcttccctt cttgctcgaa
     5221 gctttgcaat tcttgaatca aggtctgatt atcacgtaaa tgtgcagaac caggcatacc
     5281 tccaggaaga acaatcatat catagtctga taaatctcca tcaaagacat gatctgctct
     5341 tacttggatt gcatgcgaac ccgttacttg ctcttcaaaa ccaaccatat cacatgtgat
     5401 attggctcga cgcaagacat ctacaactgt caaggcttca atttcttcaa agccctgagc
     5461 taacataact gctactttta ccatgatttt ctccttattt aatttgtttt aatacaacct
     5521 ttttccgttt gaatgggact tttccgctct tttcttcagc tagattagtc tggtaactca
     5581 tcgataaaag caaaccaaca ccaatcagat tactgataat agctgatccc ccttgcgaaa
     5641 tgaaaggcaa gggaatcccc gtcaaaggaa gtagtccagt cacagcaccg atattctcaa
     5701 agatgtggaa gagcaacatc ataatcaaac ctgtggaaat ataagtgtag aactggttat
     5761 ttgatttaag agtaatcttc aacatacggt aaatcaacat gagatagagg gcaataacca
     5821 ggacagagcc aataaagcca aaatcttctg caataaccgt aaaaatcata tctgactctc
     5881 gaactgggat aagcagattc gaagcattaa atccctgacc aaataagcca ccactcccaa
     5941 tggcaatctg cccttgagcc tgctggtaag tcgttgtttg ggcaaactca aagggattga
     6001 gccaagccaa aatccgattg atttggtagg tcggcattcc aatctggtga agaaaagctc
     6061 gtccgtcctt gctaataaag atagctaaga aaccagcaac tcctgttaca gcagtcacaa
     6121 atactgggat aataattttc caagaaaccc ctgataataa aacgattcct gagaaaatgg
     6181 ctacaaaaac caaagccgtc cccaagtcac tttgaagtgc taaaagaact aggactggaa
     6241 tggtaaagag aatcatccag aaaattaaca aaaagtccag cgaaaccgtg cgtctccatt
     6301 ccttatgttt ctttgtaaat tggacaatga cacgagccaa catgaggata taggatatct
     6361 tcataaattc tgacggttga aatagggtaa ttccatttat tgatacccag tttttggcac
     6421 ccgttgatgc aactaagctt ggattataaa atacaatcgg caagatcata agtcccaagc
     6481 ctaaaatata tagaaagggg gtcaccttcc aaagaaattc tgtattaaag agcatgacca
     6541 caaaaccaat cacaagcccc aaggcaatcc aggcgacctg ctgccctaaa atgggcagaa
     6601 tattattggg ataatcatga ctaacggcta tatagatagc caccacaccg atgaccagta
     6661 gaaaaaatac tggcaagagc aaactataat cgactctaga gtcgagagaa cgtttcatat
     6721 atactaacct tatactttca tacaatacta tttatcaaag ttcattaaaa aatctatcaa
     6781 tagcctcgtc aacttcggat cgagagatgg ttttaacagt cgcttcttct gctagagatg
     6841 ctactatttg tttgccgtat cgttttccga tgattctcct atccaaaata agagttaagg
     6901 aacgttggta ttcacgtctc atacttcttc ccaaagcctg ttttaaacga ataatggcca
     6961 ttggcaattg ataatcataa aaggcatttt tcccttcttg attcagttct tgattaatct
     7021 ttttcgtcaa gggttcttga ggattttgga aaggaagcct cggtacaact tgaatcacaa
     7081 aaggatggct tgaaaaatca actccctccc agaaacttgc tgcaccaagc aagatttgtt
     7141 gttcaccttt ttcaaagcgt ttctttagct gatgaacatc cccattttta tactgggcca
     7201 agtggctaac tgtaagtaaa tccgatactg ctagaagcat gtctttagcg gtaaagagaa
     7261 ccaaaatcgg ttgctggaaa gcttgaattt ccactagtaa agcagctacc tctctggcat
     7321 agacttctaa ggaggtttct gttaccagag ggaaatcttt gaccataacc acttcttgtt
     7381 cctgttttcc ccgagattca atcttgacaa atttggcttc aggatagcct aaaaggtctg
     7441 ccaaagaaac cctctgacta atctcaagag tagccgatac tcccatggct tggcaactct
     7501 caggaagtaa agaggacaga agagtacggc ctgattttgt agaagaaata tgaattttct
     7561 tttgactcgt ttcagttact tcaagccagt aatcaccttc agctgtaaaa tagcgaacca
     7621 gctcatcaaa gccttctact tctaattctg aaaaatactg atggagattg tccagagaat
     7681 ctaagatatt tttcctagat ttaccagact gaaattgttc tatcaagtag agacactcaa
     7741 agcgaatact ttctagtatc cgttgttgaa ccctgttttc ttctcctact aaagccttat
     7801 caattaaatc gataatagat tgtatatcgt aggtctcttg aagcagattt tctagagcta
     7861 acaaaatctt ttggacttca tcaataatca gtaaacggtc actgacaaat tcaggattat
     7921 cttcaagtct ggtcacgaga taggcatgat tagtcactaa aagcttgcaa gtctctgccc
     7981 tttcttgact acgtttccaa aaatcttccg tcacaaataa gctctgggat gataaattcc
     8041 catcatgacg aaggtctgct agaaaatgtt ggtaacgata gagttgcccg atttcatcca
     8101 aatctcctgt ctctgtctca gtaagccaga ccaagacttg cattttaaag cgtctaaata
     8161 agcgattttc atcattttcc tgcaaggaat gataaaaggc atccaacttc agataatttt
     8221 gtggtccctt taagctatga atatctgtat ggaacacttc cttgaggcgt ttaccttctt
     8281 cttccatgat ttgattttga agaatctttg tcggaacact aagaacaatt tgtcgctctt
     8341 tggattgaga taaagcgggt aagagatagc cataggtttt cccaatccct gtcggcgctt
     8401 gaatcagaga gacaggttca tctttcaata gcaagccaac ctctttagca aaactttctt
     8461 gttcctccct cacttcaagg ttcaacagag aaatattttt agaaaagtct tgagatagtt
     8521 ttcgtggctc cagagaagct gccgttttct taaaatacag accttgaact tggaccaagt
     8581 ctggagaact caggatagat tggttgcgat aagtttcctc aataaccagg taggactcat
     8641 ataggagagc gtcagccatt tccagcaagc gttccaagag acctttagga agctgagtca
     8701 tcttttcccg taaaaaaaga agtaattctg ctgtagcttg ggcatctgaa agggctgtgt
     8761 gtgcgtgttt aagaggaatt cctaattctc gacacaaaat cggcaagcta tatttttcca
     8821 gttcagggaa aaagacctgg gccaattcga ccgtatcaac acgagggttt cttagctcat
     8881 agccttcaaa aaataaattt tccgccaaga gattagcatc aaactgaaca ttatgggcta
     8941 caaaaatccc atcctccacc aagtcaaata tttttctggc aacttgcgaa aaatcaggtg
     9001 cttgcgccag acgttggtct gtcaatcctg tcagttcttt gatatgagca tccaagggtt
     9061 catgtggatt gacatccgtc gtatagtgat cgacgatttc tccgtcctca atcacgacaa
     9121 ttcccacttg gataatttta gccttactac ctgtgctagt tgcctctaaa tccaccacaa
     9181 catagcgatt accaatcgtt ttcattataa aaaattatac caaaaaaagg gccatttggc
     9241 acctgcaaac ataggataat tttcaaactc aagaacacta cttttcttaa aaatcccatc
     9301 gaatagagca ttctagcctg ctgatttttt aaaatagtga agaaatacga aaaattgaga
     9361 gaagaaatgt tttcatcttc cttctctcaa cgaatcatgt attttattta accatgtcag
     9421 gatcgtagtc ataaaatcct gtatcaagga aacggttttt agggtgaagt ttacgaactt
     9481 cttcatccag caagaaggct tggtcatggc taaagttgcc ctcttgaatc aagctacgcg
     9541 cttggataaa gagttttgca atctcaacaa agttctgacc aggagtgtag agcccttcta
     9601 gtttccagcg agtaaagcca tgctccacca attctgttaa tttgatcatc aaatcaaggt
     9661 cattgttggc aaagatatgg gtcccatgat tatcttcaaa aatggaatag tggctctctg
     9721 gatcacttgg ctcagccaag aagaggtcac gtttatgcgt cttttcatca tcgatatgtg
     9781 taaagttata gtagttttgc aagagtggac gtttagaatg atggatgacg ctagcaccgt
     9841 aaaccaaaac ttcagcagga atttccaaaa tctctggcat tttgaaaagt tcagctgatg
     9901 gaatttcacg cgccaaaaca gcctcagatg cgccagcctt ttgtccccag aagttaatct
     9961 gacgactgct agttaccatg gttgaagcat cgtagatggt cttaaatgaa taaccatcgc
    10021 ggttaactac gtaaaagacg cctgcatccc caatcgtaat atagtctgtc ttgatttctt
    10081 ccaagaagtc taagaaaggc ttgatacggt ccatcatatc ttggtgcatg agagcattga
    10141 ccgcaacgag caattcctta ccagcatcat gaaccaactt agcgatttca cgtaattggt
    10201 cataactaaa ggtcgttggc agacgaaggc caaaatcttt ctcaccgaca tagatacggt
    10261 ctacgccagc ttcgagtagt tgttcaactt gttcaatact ttcagcagtt gctgtaatga
    10321 caatcttttc cataagaaaa attataccac atttctccaa aatcatccat gctttgaaaa
    10381 tgaaaaggga ctttattctt tttgtaacct ttctgtaata attctctgcc gaaaaaatga
    10441 taaaataggt atgtactgtt aaggagagaa ttatgcccgt aagaaaatta caatcctatg
    10501 aggtagacta tcaagaagaa ttaaaccagc agcttcctca ttaccaagct tatacacctg
    10561 aagcgcaatc tgatgccaat ctcaaggaaa tcctattttt tattaatatc gctgtttttt
    10621 gtatctgtat tgctatcttt agttttatct ttttagcatt aaaattatca actgctcttg
    10681 cctttgccgc agcaatcgga ttcagcttac ttgttttaaa agttcaacgg tctattatca
    10741 aacgaaaacg tagaagataa atccaaaata tcgccccagt tggagcgata tttttatttt
    10801 ttctttttag atggtgtctg aatggcaatc ttcacttcaa agattgttcc cttgggttta
    10861 ttatctttga cagtaacagt tccttttaga gcatctacaa tttgcttggc tagggataat
    10921 cctaaaccaa aaccaccttt ttgccgagtt ctagccttgt ctactcgata aaaacggtca
    10981 aaaattttct ttttatcttc tgtcgaaata ccgattccat tatcagaaac aagtaaataa
    11041 agattgcgat cggtcgccga gataagaaaa tcaatttcac catcctcctc agtatacttg
    11101 acggcattat cgaaaagaat ggtcatcagt tgtttcagaa gaagctgatc tgtgacaatt
    11161 gttcgatgga tacgattttc aaaacggaag acacgattat tttccgaagc aatcatctcg
    11221 tagtttgtga aagttgtatt aaaaaagcta gttggaactt ctgcaagctc cggcttaatc
    11281 ccatcatctc tccgagctaa gttcagcaag cttgtcgtta aaaaacgcat atttcggact
    11341 tcttccaaac tcgatgcaat gctttcgctc acatccataa tggtagcttc tggcttacga
    11401 aaaagggtct ctaagcgatt ttgcaaaact gcgagtggag ttcgtaactc atgactggca
    11461 ttttccacaa aagactgttg cttctgcata ctctcaagca ggggcctaac actgacccta
    11521 gctagataga gactggcaag taaagacaaa atccagaaac tagccatcac gaccacaatc
    11581 aattgctcat gcttttgact agcctgttcc aactgactgg tattaatcaa gacagcagca
    11641 tacttgatat tggttgaaac cgaactaata ttggtctcca tcaaaatcac acgatagatt
    11701 tcttcctgcc catagctatt aaaaacctga atctggtaga tatgtcctag ttctttcttt
    11761 tctaacttaa tcttatccaa gcccaaaaat cgatttccag aaagaagttg agtaaagtct
    11821 ttatcaaaga gaatgacttc cgtattggaa ctgacattag gttttatttc tactttacta
    11881 gcgtccgccc tagcattttc taaatcttta atctcttctg ttgccctatt tatagccagc
    11941 tgaataactg cttgaggatt ttcactcagt ccatgaagct tatcgtccac cgaagtataa
    12001 agactcgaat gcatgacttg taaaataatc agagtcattg tagaaaaaat cagggtgaag
    12061 acaccgaagt tgcggataaa ataactaaag tcatccgcat accatgtttt tttaagttta
    12121 ctgaacatct tttaaaagat acccaacact acgcaaagtt tgcaaattct ctgcaaaagt
    12181 ggttcccttt aatttcttac ggacttttga aacatagact tcgacaaccg aaatcgttgt
    12241 atcactatca aatccccata gacggtcaaa aatctgcgtc ttaggcaaaa tcacattttg
    12301 attttgaagg aaataaacta gtaaatcgaa ctctttcccc agcaattcga caggagtatc
    12361 ttcaacttta acggtattgg ttgataaatt aaccacgata ttcccataag tcaaggtgtt
    12421 ttcattaaac ttccctgaac gtttgagaag ggcctgaatc cgcattttaa gttcttctag
    12481 gtagaaaggt ttggtcagat aatcatccgc tcccagttca aatccatgtc ccttgtcatc
    12541 caaactttcc ttggcagtca taatcagaac tggtgtcgta attccctttt cacgcaattc
    12601 ttttaagact tggaaaccat ttttttctgg caacatcaaa tccagcaaaa tcaagtcata
    12661 gacaccactc tcagcttcgt agagaccttc ttctccatca aatacctgca taacatccgc
    12721 aaaatcgtct aaaaagtcaa atactgaatt tgacagacct aggtcatcct caaccaataa
    12781 gatttttatc atgagaaact cctccttatt aaaactatta taccaaattt gccttaaaaa
    12841 aaactcaact ctctgcattt tacatgagat agctgagttt tctttttatt ttaggcttat
    12901 ttatgcattt ccgtattgaa gaacaactgc ttcgactgca gctttttcac ggctaatcaa
    12961 gtcaacacgc gctgcaattt ccttgattcc cataccgatg ttacggctaa gagcaaggtc
    13021 agaaagttgc ggctcaaaga actccttgta ttccgccaag cgttgctgag tcttaaatac
    13081 atgagcagga aggataacaa agctatcaaa gctcatatct cctccaaggg ctgccttaat
    13141 ccaagcccag ttttcacgcg cccaagacca agctgttttc tgagttgctt gatgagctag
    13201 gaattggtaa taccaagcag acaagtcctg tggtttgacc acaaatttgt ccttccaaga
    13261 agtaatcaag ttttggatat tatccgcatc tgtactgtat gcaagagctg ctgccaactg
    13321 gcgtttaaag acagcatctg ttgcgtgagt ataagtatca agataaagtg ctaacaagtc
    13381 tttagtctca tgatgtttca tctcattaat cagaacttgt gaacgaatag ctgctgggag
    13441 tcctgcaaga ttctccttgt gtgttgcgaa gatttggcta gcgacttgac tagcttctgc
    13501 atcatttgag cgaatcatca tcgaaacagc cagctgacga accaattcat cctcatctga
    13561 ttctccgtct ttagcttcaa aaccaagacg gtcatagtta tgacgagcca atttagcaac
    13621 cagtcctttg aaggctgttt cagcatccgt tccttcatca ataaagcgct caagggctga
    13681 aatcacttga gaaacagctg aaaccaccag ataagactct tccttagcaa gtttatcaag
    13741 aactggaagc aagtctgcat aagcaatgtg ccctgcctca gccaacaaac gacgttcttg
    13801 aacaatttgc agtttgcttg tgttatcaag tgtctctagc tcagcaagaa cagcttctaa
    13861 caagtctcct tgatagtcgg taatatagtg ggcagtattt tcagtgttga gacgaagagc
    13921 tccttcattt tcagcaagaa gagctgcgta gccagggatt tcgatacttt cagtttcgag
    13981 tgtatcaggc aagcctttcc agttgctatt gaggggcacc acccagagac ggttcttgtc
    14041 ttcgttctca ccgatgaaga attgtttttg tgaaatcttc aagacatcat tttcaacttt
    14101 aacagtaaga actgggtaac caggctgttc caaccaagaa tccatgaagg ctgcgacatc
    14161 acgtcctgac gcttgaccaa gggcatccca aaggtcacta ccaatggtgt tgctgtattg
    14221 gtgtttttca aagtaggcgt gcaaaccttt agcaaaatca gcatctccta gccaacggcg
    14281 aagcatgtgc atgagacggc ttcctttggc atagacgata gcgccgtcaa agagtgtatt
    14341 gatttcatct ggatgtttaa cttcgacgtg gacagactga acgccatcag tagcgtcacg
    14401 ttcaagagca agaggtactc cacctgtttg gaaatcttca aagatattcc agcttggttc
    14461 gatggtatcc acacagacgt attccatcat attagcgaaa ctttcattga gccaaaggtc
    14521 atcccaccat ttcatagtca cgaggttccc aaaccattgg tgagccaatt catgggccac
    14581 aacaagggca acttgttgac ggctagcaaa tgtagagttc tcatcgacaa ccaagtaaac
    14641 ttcacggtag gtcacaagac cccagttttc catagcacca gctgagaagt caggaagggc
    14701 gatgtggaga gattgaggaa ttgggtactt aactccatag taatcttcgt aaaactcgat
    14761 agagcgaaca gcgatatcca gtgagaaatc aagatttgaa agtggatgtg ctttggttga
    14821 gtagacacct accagggtac catttttagt tttagcggtc accccttgca aatcaccagc
    14881 aacaaaggcc aacaagtaag aagacatgcg aggtgttgtc tcaaacttcc agatacctgt
    14941 ttccttacgg ttttcaacat cgatttctgg catgtttgac aaggccaatt caccttctgc
    15001 ttggtcaaag cgaagagaga ggtcaaaagt tgctttggct tcaggctcat ccacacatgg
    15061 gaaagcttcg cgcgcaaaat ggctctcgaa ctgagtagac aagacctcct tcttgactcc
    15121 atcaactgta taataagaag ggtaaatccc tgtcatgttg tctgtaattt taccagaaaa
    15181 ggcaagaacc aattcaactt gaccagcctc agccaattcg atatgaaggg cttcattgtc
    15241 atggtcaact gtaaatggac gagcttgacc tgcaacttct acagaggtga tttccaagtc
    15301 tttttggtgg agggagatgc ggtcactctg tgcttgacca gtgatggtca ctttcccaga
    15361 aaaagtcttg gtctcacgac tcaaatctaa aaataaatca taatgttcag gaacaaattg
    15421 cttaataaaa tgttcaactg cttgcatagt tttctcctat tctaagttta agagctactg
    15481 ctcttcttca aacaaactta ttatatcata ttttgcttga gaaaaaagga ttggacagcg
    15541 atttccaaaa ctttcttcct tctaaatagt ctacagtggg tagaccttgc gaaattcttc
    15601 taaaacaacc ttgctttcag gtgtaaaagt cagccctact tcacccaaac agtctgtgaa
    15661 aaagtcctca tgaacctggc gccaataggc aagtgatttg tctccctcac cttccttaaa
    15721 ggcatgttgc gcagaaactt gattgaagag ttcaacagaa acctttgtaa tttcgacaat
    15781 gcagacagac tgattttgac tatctaaaat gacatcgaag gtccctactt ggggaagtgg
    15841 ttcgtcttct agtacataga ggtcataggc tgatgctgtt gctgtctttt ctcctttaaa
    15901 caccaaatcc gctaaaaggt ctggttcaac tccaaaagcc caagcatcga tttcatctcc
    15961 gatcaaagga ttgatttgct tgtatttatt ccacatttct tgcggtatca tgggtactcc
    16021 tttgtaattt tttactttct tcttttatgt gtttaagatg atctggatgg tcaatctcta
    16081 aatcaaaaat ctctggaata gaactgtagt ggataatgca cttgataccc aactgattca
    16141 ttttttgtat gaaagaagta ttcagatagc ctgctacagc aaaattaatc ttgttctttc
    16201 ttgctttatc ctgcatatct cttagcatat ctaacattat tggactttcc agatcatgcc
    16261 attgactgtt tctcatagtc gcaaaaacaa aggaagtcaa atcattcatt ccaactacaa
    16321 tctttgaaat gcccgtttcc agtatactag ataagtcaaa atacgctgac ggtaattcaa
    16381 tcatcgttcc gactttccca gtaaagccat actgacgcaa tactgtaata gcttgtttta
    16441 attggtcggc atcattgaca aaaggaaaga taacagatag attggggttg gtttgataaa
    16501 cttctgtaac gacatgtgct tcagcctgaa attcatccaa acacgccagt aaacgcctgg
    16561 ttcctctata gccaaacaag ggatgccctt cgtcaaaaaa ctctttagtc cccactaaac
    16621 aattggcttc tgtattcgtt aattcagtaa aacgatacca aacttcttca tctgagtaca
    16681 gggagcagat agtctctaga taatctttta caaattgctg acaacttgct aatatgatgt
    16741 tttgattaag ctctctcaac aaatattccc cacgaatcat gccgacgtgg tgaaatagtt
    16801 gaggataaat tttttcaaga attttttcgc cactaagggc aagttgattt ctcatagcca
    16861 ttcacctcgt cttaaaagat acaatatcat atataattat atcaaaattt cctctagttc
    16921 aaaagcttca taaggttcag ataactcata tcctaaaaat tctgctactt ttttggaagc
    16981 ctcattatga gcatcccaaa gtggaaacat atctctattt aaactctcta gaatcattgc
    17041 agcaccaagc tttttagcaa atccatttcc ttgttcgttt ggtctagttg caacttccac
    17101 ttcaactgct ttacggtaaa ctaaccctga ggaaatccca gcaatcagtt cattattttt
    17161 aagaatcaca aagccaaatc caccttttaa aacaaaatcc tgataggact caaaatcccc
    17221 ctgtaaatcc tgtgaccatt cttccgtaga aaagcagtta taaatatgat tatcaatagg
    17281 cacaatattg taaccttcct ctaaatgagt aactagatta tttaaaaatt caacttgaaa
    17341 atttgcctta tctttaaaag aatagcgagt aaaagaattt agccccactt ttcgatgcag
    17401 aaaatcttgc caattagtat tttctgaaat aataatctta taatctaaac catattttct
    17461 aacaaaatct tcccaaaatc tggaatccaa ctcccctgct aggtatagaa aattcccaac
    17521 atcataaaag cttgttgtcc tatcattgtt tcggtagaca gttccaattt gagatttaag
    17581 accatagaga accatatttt tcttccatgt tttaaatagt tccattatcc ctctacttca
    17641 ccttccaatt catgtaagaa gtcttgtcca gttctggaaa tcctaataat tcagacttaa
    17701 ccttcaagac taatggcgat gcattttctt ctgtaatctc ttgaatatcc atccaaatat
    17761 atccaagtga atcattcgca ccatcagaca cagcttccga agtcgtaact tgaggtgcac
    17821 tctcattcat ttcaacatca tacaaggcca tgacatggtc aaccataaaa tttgttaact
    17881 cttctctgac gaaaacatcg tagattcgag gattagagta gcttctaaca gtaaatcccg
    17941 tctcttccat aacttctcta gtcagcgttt ccgtcagtcc ttcaccaagt tgctgactgc
    18001 ctccaggtag atcataccga tgttgataag ggcctctcgt tttttcaatg cagagtaact
    18061 tcccattttc taagcaaaca gcgtagactc caaagtgttt tttgatttcc atccaactcc
    18121 tcctacttca aagaccagcc accatctatt gtcaagattt gtccttgcat ggcgctcgct
    18181 tttccacttg ctaaaaaaag actaagctct gctatttcct ctggctcaat ccagcgcttg
    18241 attggagttt cactagccac ccagtcagcc aaaccacctg gttcaaaatc cgcagcggtc
    18301 atagctgtct tgactgctcc tggagcgata ccaaagacct gaatcccagc ttcagcatag
    18361 tctagagcca actgcttggt gaagccagcc aaggcatgct tggatgaagt ataggcgtga
    18421 ccacctccac ctgctaggct agaagcaatg gaacacatat tgatgatgat tcccttttta
    18481 ttttccagca tttgtgtcaa ataataccga gtcaactcta ctggaataat gtagttgatt
    18541 tcaaaaatct cttgaatgtc ctgcgccgtt tgttccaaca gtggtttgta atcatccaaa
    18601 actccagcag tattacacaa aacatccacc tgagggcacc agtcaaaaat aggttccaag
    18661 tccaaggtca aatctctctg taaaaagtga aaatcaccct ctaagagtgg cttttcacct
    18721 tggtcaactc cataaacttg atagcccttc tctaaaaaga ggcgagcttg agccaatccg
    18781 atccctgaac tcactcctgt aatgagtaca cgtttagtca tgcacttcta cccaatccgt
    18841 tgccaaaaca tcacaaactg tcgggctcca catggaaaaa ccttctcctt cgccagaaac
    18901 gttgattagg aaataaggtg tcatttcaag tgcaagccca ttttgctcga tggtatcaaa
    18961 gagttggaca tagttttccg cacctcccca accagttcgt acatattttc tcttagcctt
    19021 taacccaggc aggatctctt caaatgtcat gtttttctcc tttaattcta cattcttcat
    19081 ttaattatag caaaaaaccg ctttatacgg ctttttgaat gtgagttatt caaacctgct
    19141 actacttacg gcaaattatt ccctgcagca agataaattt cataccattc ttttcttgtt
    19201 aagctaaagt ttgccgctcg gctaacttct ctcaagtgct taggatttgt tgtacctacg
    19261 actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt tgaagaggtt
    19321 actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa tttctcattt
    19381 ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg aatgaccaca
    19441 tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg actatcttcc
    19501 atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa ttgtagctga
    19561 ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat aggattttga
    19621 ttagaaactc caaaatctcg aactttacct tgtttataaa ggagattaaa ggcttctgct
    19681 acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc tagatgatca
    19741 atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt agaaaaatca
    19801 aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat cttttctctt
    19861 aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc acgaccataa
    19921 atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac aagctcttca
    19981 acttctttta cagacttatc ttttattctc atcattccga gaacaatttc tgataattct
    20041 ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa tttctaacat
    20101 tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat acttcactcc
    20161 attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg acagctaaag
    20221 gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa cggagcagag
    20281 aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc gcttctttcc
    20341 aattccaaat accgataact agcgaaatcg taaagacaga caaactatcc cagggagccg
    20401 gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct aaaacaacta
    20461 gaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga gaatcttgga
    20521 ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa ataagaagtt
    20581 gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa tcacttagta
    20641 gttgataata acgtaataca gccaggacaa gaattggcgt caaaagggac tctttgatag
    20701 aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc ttacctagat
    20761 aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc atcaaataga
    20821 tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa ctttcccaca
    20881 actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg cttgtttctt
    20941 cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct actttttgac
    21001 tcaaatcgtc ccattgctgc caaaagactg agacacgctc ttctccttct ttcgttaatg
    21061 aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt atccattgat
    21121 ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta tcaaatccag
    21181 cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca atcatatcca
    21241 agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact tctcccttct
    21301 aatctatttt gtaataccta ctagtaactt cacctatagt atattacttc tacactagtt
    21361 tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca gcgtcgccct
    21421 accgtatgta tggttactga cttcgtcagt ttcatctaca acctcaaaac agtgttttga
    21481 gctgacttcg tcagtttcat ctacaacctc aaaacagtgt tttgagctga cttcgtcagt
    21541 ttcatctaca acctcaaaaa catgttttga gctgacttcg tcagttctat ctacaacctc
    21601 aaaacagtgt tttgagcaac ctgcggctag cttcctagtt tgctctttga ttttcattga
    21661 gtataaataa aaaaacagaa ctagtctgaa ctagtcctgt ctacttttac ccaatcacac
    21721 ttccatttgg tacagctgga tcaactgtga gaagggttaa tttgccatca tattcagctg
    21781 atagaatcat accctggctg acatattttt tcatcatttt acgtggtttg aggttagcaa
    21841 cgatttgaac tttcttgccg accaattctt gttcatttgg atagtatttt gcaattcctg
    21901 aaagaatctg acgatcttct ccatcaccag catccaagcg gaattgaagc aacttatctg
    21961 aaccttctac tttagacact tctttgactt ctgcgacacg gatttcaacc ttgtcaaagt
    22021 cttcaaactt gatttcatcc ttgtttagtt tgagctcaac ttcgtccgga ttccattctt
    22081 tttcgactgc tggtttattg ccttccattt gttccttgat ataggcgatt tcttcttcca
    22141 tatttagacg tggaaagata ggtgttcctt tggcaactac agtcacatct gctgggaagt
    22201 cagccaaact caagttttca agactagaaa cttcttccaa accaagttga gtcaaaactg
    22261 cacgactagt ttccatcata aatggttcaa tcaagtgagc aactacacga atgctggctg
    22321 ccaagtggct catgacactt gccaattggt cacgaagagc ttcatccttg gccaagaccc
    22381 atggtgcggt ctcatcgatg tatttattgg tacgagagat cagagtccag actgcttcaa
    22441 gcgcacgtgg atagtcaact gcttccatgt gtgtatggaa gtctgcgatt gattgttctg
    22501 caacctcagc aagaacatga tcaaattcag tcacaccttc tacataggca gggatttgtc
    22561 catcaaagta cttattaatc atggaaaccg tacggttaag gaggttccca aggtcattag
    22621 ccaattcata gttgatacgg ccgacatagt cttcaggagt aaaggttccg tctgaaccaa
    22681 ctggaaggtt acgcatgagg tagtaacgaa gtggatctag tccataacgc tctaccaaca
    22741 tttcagggta aacgacattc ccttttgact tagacatttt tccgtctttc atgacaaacc
    22801 aaccatgggc aatcaaacga tcaggtaatt taacatccaa catcataaga aggattggcc
    22861 agtagataga gtggaagcga aggatatctt ttcctaccat atggaagact gttccattcc
    22921 agaacttgtc aaagttacca tgttcgtctt gagcgtagcc aagagctgtc gcatagttaa
    22981 gaagggcatc aatccaaacg tagacaacgt gttttggatt tgatgggaca ggcactcccc
    23041 atgtaaaggt tgtacgagat accgccaaat cttccaagcc tggctcgatg aagttgcgta
    23101 gcatttcatt aaggcgacca tctggcgtga taaattcagg atgagctttg aaaaattcga
    23161 ccaaacggtc ttggtatttg ctaaggcgaa ggaagtatga ttcttcagaa acccattcaa
    23221 cctcatgacc tgatggagca ataccaccag tcacatttcc agcttcatca cggaaaactt
    23281 ctgccagctg gctttctgta aagaattctt cgtctgatac tgaataccaa ccagagtatt
    23341 cacccaagta gatatcatct tgagcaagta agcgttcaaa gacctgtgcg acaacttttt
    23401 catggtagtc atcggttgta cggataaatt tatcgtatga gatatctagt aattgccaga
    23461 gttctttaac tccaaccgcc attccatcaa cataggcttg aggtgtaata ccagcttctt
    23521 ccgctttctg ctggattttc tgaccatgtt catcaagacc tgtcagataa aatacatcgt
    23581 agcccatcag gcgtttgtaa cgtgctagga catcacatgc gatagttgtg taggcagaac
    23641 cgatatgaag tttcccagat ggatagtaaa tcggcgttgt aatataaaaa tttttttcag
    23701 acataatttt tcctttccag gcaaatgaaa cctgtttttc taacacttca ttatatcaca
    23761 tttttaatga atttcgatag ggaaatccat acaaaaacaa gatagacgag tgtccatctt
    23821 gttgatctca ttcataacga agggcttcaa ttggatcaag tttcgatgcc ttgttggctg
    23881 gcaagactcc aaaaatcata ccaacactag ccgaaactgc aagactaaat agggcaactg
    23941 ggattgatac tccaacttct ataccttcta ttaaaccttg cagtaacaaa cctgctaagg
    24001 cagttaaacc acttgcaatt gtcaagccaa ttaagccacc taacaaggtc aaaatcatgg
    24061 attcaatcaa aaactgaatt aaaatattgg cacgtgttgc acccaaagct ttacgaagac
    24121 caatctcacg agtgcgctct gtcaccgaaa ccagcatgat gttcatgaca ccagttcctc
    24181 caacaaagag agaaatccct gcgatggaac taataatcgt cgtcataaaa ctaaacgatt
    24241 gttgaatttc tgcaaataca acggactcat ctgccacctg gtattctccc tgttgtaagc
    24301 ctgcaagctc tgtcattttt cgtgccagtt ctggacccag agttggggtt aaactggtat
    24361 cattcactcg aaagacaata ctagctattt catctatatt aaaattcgca gcaagggaga
    24421 tattggtagt aataggcaag ccaccaaacc catatatttt tgacttttta gcctccggac
    24481 tagtataaac cccaatgacc cggtaactaa atccattgac ttctacaacc ttgttaatag
    24541 cctcttgagg agattcaaat aaactaatgg acaattcctc atctagcaaa ataacacttg
    24601 caaactcttt gaaatcttgc tctctcagac tacgacctgc aataatttca ttcttaacag
    24661 cgtccatgta agttctgttt ccacctgtca aattagcatt ctcaaccttt ttatcttgat
    24721 aggtcaagat ggcattcgtt gaattggtta catagtaact atccactccc ttcagtttag
    24781 ctgcctcttg aacccaggat tcttgcggtt ttggcggttc aacaggaact tcctcttcct
    24841 ttccagaaac cgtaaaagct gattgtttct gagtaaaaga cccatcttta ctttttttag
    24901 gagagaaaaa gacgctaata tttttctgag atttagtcat atctttattg acttgacgag
    24961 atagggaatc acccaaagcc ataatcacaa caactgatga aacaccgata ataatcccaa
    25021 tcatagtaag caaagaacgc atcttgtgag ccatgataga tgaaaaggca aatttcagat
    25081 tctgcatctt agttttcctc ctttcctaac tgagcactgt cagacgaaat gaccccatcc
    25141 cgaatgacaa tctgacgttt ggcataggca gcaatctcag gctcatgcgt taccatgata
    25201 atggtttttc cttctttatt caaatcaacc aataattgca taatttggtt acctgttttg
    25261 gtatccaagg ctcctgtcgg ttcatccgct aggataatag aaggattgtt taccaaggca
    25321 cgcgcaatgg ctacacgttg cttttgacca ccagataatt ctgaaggtaa atggtgacta
    25381 cgttctgtca attcaacctt gtctaaatat tcctcagcca acttgcgacg ttttgaagac
    25441 gaaactcctg cgtaaatcaa gggcaattct acattttgca gagcattgag cttcgataga
    25501 agaaagaact gctgaaagac aaaaccgatt tgttggttac ggaccttagc tagttgtttt
    25561 tcaccaagcc cagccacttc ttgaccttca agataatatt ctccactggt tggtgtatcc
    25621 aacatgccaa tcgtattcat cagagtggac ttaccagacc cagatggtcc catgatggct
    25681 acaaattcac cctcattcac ttctagattg atatttttga gaacctgcag ttcttggtca
    25741 ccattacggt aacttctgaa gatatttttt agactaatta gttgcttcat cagccttcac
    25801 ctcttttcct tcttccaagg aagatgttgg attactgatg accttagcac cgttcgttaa
    25861 accagaagtg atttcttgat tttctgcgtc agcatttccc aatgaaacct caactttttt
    25921 agccttttgt tgttcatcca caatccagac ataattttta ctatcatcca ttactagact
    25981 gctaacagga ataagaatag ccttagtttt gcttttaacc tcaatgttga cagaaaaacc
    26041 ttgtttcaaa tcaccaacct cgcctgtcac atcaatagta taagggtatt tagaacctgt
    26101 attattcccg gctgctggac tagctgcttc accattgttt ttaggatagt cagaaatata
    26161 gcttaatttc ccagtccatt ttttatcagg atacacttta gaagtaaagc ttacttcttg
    26221 acctacagaa aggttggcta gattgtactc agacaattct cccttgactt gtaaattttc
    26281 attgctgaca atatgaacca taacttgact cgcccctgtt ggagatttag aaacattgct
    26341 attgacttcg actacagttc cctctagggt actgagaaca gttgttgcat ccaattgact
    26401 ttgagccttg cttaattgcg ctgcagcatc tgcacgcgca tcacgggcat cacccaattg
    26461 agcatcaata gaagcaacag aatttccagc cactggagtt gggctttgca ccgttgcatc
    26521 ttctcctcct actggcgctg gtaactgtgg agcctgagct gaagcggctt catttcgtgc
    26581 ttgattgagt tcattgatat gacgatctgc cttagctact gctcgactag ctgaatcata
    26641 ggccgcctgc gcttctgaac tactgtactt gactaaagcc tgcccttcgc tgaccttatc
    26701 gcccacagaa acaaggattt catctaaatc acccttacta gcatcaaaat aaacatattg
    26761 ttcatttttt gctgttactg tccctgacaa taaaacagag gatgccacgc ttccttcctt
    26821 ggcaacaaca agatgagtag gctcatcttt tacagcagtc tgagaaggtt gtctaaaaag
    26881 taaaatcccc ccggcaccca atacaactac actcgcagca ccgattgctg catacagttg
    26941 ccacttttta gctttaccat tctttttctt cataatgaaa ctccttttct tttttacaat
    27001 actttgctat tataccaaat ttccctccag caaacaatgc agttcagatg gaaataatgg
    27061 cagttcagga ttaaacaatc gttcggaatt ttgcttttct attgtactag atatataata
    27121 cactatcttg acttatttgg caagcttttt tgcaattttt tgtgcgtagc agatttttgc
    27181 aatcaaatca aaaaaagaat aaaatataac tatcaaaaaa gacactctac tatttaaaag
    27241 attacaaagg agttttcaat gagagaatat gatatcattg ctatcggtgg aggtagcgga
    27301 ggaatcgcta ccatgaaccg tgctggtgaa catggagcca aagcagccgt tattgaggaa
    27361 aagaaattag gtggaacctg tgtcaacgtc ggttgtgttc ctaaaaaaat catgtggtac
    27421 ggggcgcaaa tcgctgagac tttccatcaa tttggagaag actacggctt taagactact
    27481 gatcttaact ttgactttgc aaccctacgt cgcaatcgtg aagcctacat tgatcgcgct
    27541 cgttcttctt atgatggtag ttttaaacgc aacggtgtag acttgattga aggtcatgct
    27601 gaatttgtag attctcatac tgtaagcgta aatggtgaac tgattcgtgc taaacatatc
    27661 gtgattgcta caggtgccca tccaagtatt cctaatattc ctggtgctga gctaggtggc
    27721 tcttctgatg atgtatttgc ctgggaagaa cttccagagt caattgccat tctaggcgct
    27781 ggttatatcg ccgttgaatt agctggcgta ctccacactt ttggtgtcaa gacagatctc
    27841 tttgttcgcc gcgatcgtcc tttacgtggt tttgattcct acatcgttga aggtttggtc
    27901 aaggaaatgg aaagaacaaa cttaccactt cacactcaca aagtccctgt caagttagaa
    27961 aaaactactg acggcattac cattcatttc gaagatggta ctagtcacac agctagccaa
    28021 gttatctggg ctacaggtcg ccgtccaaac gttaagggct tgcaacttga aaaagctgga
    28081 gtgactctga acgaacgtgg ctttatccaa gtggatgaat accaaaatac tgttgttgag
    28141 ggaatctatg ctctaggtga tgtaacgggc gagaaagaac tgactccagt tgcaatcaag
    28201 gccggacgta ccctatctga acgtctcttt aacggaaaaa ctactgcaaa aatggattac
    28261 tcaactattc caactgttgt cttttcacac cctgctatcg gaactgttgg tttgacagaa
    28321 gagcaagcta ttaaagaata cggtcaagac caaatcaagg tttataaatc aagctttgca
    28381 tctatgtact ctgcttgcac tcgcaaccgt caagaatccc gtttcaaact cataacagct
    28441 ggttcagaag aaaaagttgt cggacttcat ggaattggct acggcgttga tgaaatgatt
    28501 cagggatttg ccgttgctat caaaatggga gcaaccaagg ctgactttga tgcaactgtg
    28561 gcaattcacc caactgcatc tgaagaattt gtaaccatgc gttaatcgaa acaaaagaag
    28621 ctgatataaa tatgtctgct tcttttt
//
LOCUS       DAVAZV010000024        28564 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVAZV010000024 DAVAZV010000000
VERSION     DAVAZV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 28564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28564
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.024"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..190)
                     /locus_tag="VQT46_001031"
     CDS             complement(<1..190)
                     /locus_tag="VQT46_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2371072.1"
                     /translation="MYEESKQLTNAQFKRLVGVQRTTFKEMLAVLKTAYQLKHAKGGR
                     KPKLSLEDLLMGTLQYVRE"
     gene            536..1489
                     /locus_tag="VQT46_001032"
     CDS             536..1489
                     /locus_tag="VQT46_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2371073.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLISLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            1540..2730
                     /locus_tag="VQT46_001033"
     CDS             1540..2730
                     /locus_tag="VQT46_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET2371074.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGTDAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            2879..3250
                     /gene="rnpA"
                     /locus_tag="VQT46_001034"
     CDS             2879..3250
                     /gene="rnpA"
                     /locus_tag="VQT46_001034"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET2371075.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            3225..4049
                     /locus_tag="VQT46_001035"
     CDS             3225..4049
                     /locus_tag="VQT46_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET2371076.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAKIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            4068..5054
                     /locus_tag="VQT46_001036"
     CDS             4068..5054
                     /locus_tag="VQT46_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET2371077.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSKTFYVTINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            5105..5728
                     /locus_tag="VQT46_001037"
     CDS             5105..5728
                     /locus_tag="VQT46_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET2371078.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPGWQLQQTSQWMNQAQRLRPHFWVYLQRDEQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            5859..7316
                     /locus_tag="VQT46_001038"
     CDS             5859..7316
                     /locus_tag="VQT46_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET2371079.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            7339..7620
                     /locus_tag="VQT46_001039"
     CDS             7339..7620
                     /locus_tag="VQT46_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2371080.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            7697..8182
                     /locus_tag="VQT46_001040"
     CDS             7697..8182
                     /locus_tag="VQT46_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2371081.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            8199..8864
                     /locus_tag="VQT46_001041"
     CDS             8199..8864
                     /locus_tag="VQT46_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET2371082.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            8868..9731
                     /locus_tag="VQT46_001042"
     CDS             8868..9731
                     /locus_tag="VQT46_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET2371083.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SRGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            9733..10437
                     /locus_tag="VQT46_001043"
     CDS             9733..10437
                     /locus_tag="VQT46_001043"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET2371084.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            10616..12289
                     /locus_tag="VQT46_001044"
     CDS             10616..12289
                     /locus_tag="VQT46_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2371085.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            12401..13492
                     /gene="ulaG"
                     /locus_tag="VQT46_001045"
     CDS             12401..13492
                     /gene="ulaG"
                     /locus_tag="VQT46_001045"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET2371086.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            13606..15582
                     /gene="tkt"
                     /locus_tag="VQT46_001046"
     CDS             13606..15582
                     /gene="tkt"
                     /locus_tag="VQT46_001046"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET2371087.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVTDYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDANRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            15699..15998
                     /gene="yajC"
                     /locus_tag="VQT46_001047"
     CDS             15699..15998
                     /gene="yajC"
                     /locus_tag="VQT46_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2371088.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVEGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            16045..16473
                     /locus_tag="VQT46_001048"
     CDS             16045..16473
                     /locus_tag="VQT46_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET2371089.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            16475..16885
                     /locus_tag="VQT46_001049"
     CDS             16475..16885
                     /locus_tag="VQT46_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371090.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            17185..19836
                     /gene="adhE"
                     /locus_tag="VQT46_001050"
                     /gene_synonym="adhC"
     CDS             17185..19836
                     /gene="adhE"
                     /locus_tag="VQT46_001050"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET2371091.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITEPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
     gene            complement(20821..21129)
                     /locus_tag="VQT46_001051"
     CDS             complement(20821..21129)
                     /locus_tag="VQT46_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2371092.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(21126..21434)
                     /locus_tag="VQT46_001052"
     CDS             complement(21126..21434)
                     /locus_tag="VQT46_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2371093.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(21439..22734)
                     /locus_tag="VQT46_001053"
     CDS             complement(21439..22734)
                     /locus_tag="VQT46_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2371094.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPSAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGIVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(22752..24161)
                     /locus_tag="VQT46_001054"
     CDS             complement(22752..24161)
                     /locus_tag="VQT46_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2371095.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYGNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSLCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            24319..25047
                     /locus_tag="VQT46_001055"
     CDS             24319..25047
                     /locus_tag="VQT46_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2371096.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            25507..25701
                     /locus_tag="VQT46_001056"
     CDS             25507..25701
                     /locus_tag="VQT46_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2371097.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSDVTLITGKNGTGKSTLL"
     gene            complement(26067..27377)
                     /locus_tag="VQT46_001057"
     CDS             complement(26067..27377)
                     /locus_tag="VQT46_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET2371098.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNFAITNGTLDVLAQHILYRTRTYPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYRKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTSIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            27614..28486
                     /locus_tag="VQT46_001058"
     CDS             27614..28486
                     /locus_tag="VQT46_001058"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET2371099.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         8947 a         5086 c         5949 g         8582 t
ORIGIN      
        1 attctcgcac atattgaaga gtgcccataa gaaggtcttc taggcttaat ttaggttttc
       61 gtccaccttt tgcgtgttta agttgataag ctgtttttaa tacagctaac atctctttaa
      121 aagtcgtgcg ctgaacacca acaagacgct taaattgtgc attggttagt tgtttacttt
      181 cttcataaat tttattgtat catatttttg tttcacagga agtctaataa ataaaaattc
      241 tttaaaattt tgttgggaaa atgggaaaag atataaatgg aaacttagta taacacttgg
      301 aaaactctgt aaaaatagta agtcaattca tgtcccgttt tttctctagg gaagttgggc
      361 ggctatattt atatgaccat ttgtcgtaat aaacatccct accaagggtc aatagaaata
      421 aattcaacga aacttttgct gtcagattta gatgcccaat ttgtcattta tactctttca
      481 tataggactt tctataagga tggaaaaaag aagggaaatt tgataagata ggaatatgga
      541 ttttgaaaaa attgaacaag cttataccta tttactagag aatgtccaag tcatccaaag
      601 tgatttggcg accaactttt atgacgcctt ggtggagcaa aacagcatct atctggatgg
      661 tgaaactgag ctaaaccagg tcaaagacaa caatcaggcc cttaagcgtt tagcactacg
      721 caaagaagaa tggctcaaga cctaccagtt tctcttgatg aaggctgggc aaacagaacc
      781 cttgcaggcc aatcaccagt ttacaccgga tgctattgct ttgcttttgg tgtttattgt
      841 ggaagagttg tttaaagagg aggaaattac tatcctcgaa atgggttctg ggatgggaat
      901 tctaggcgct actttcttga tctcgcttga taaaaaggtg gattacttgg gaatggaagt
      961 ggatgatttg ctgattgatc tggcagctag catggcagat gtaattggtt tgcaggctgg
     1021 ctttgtccaa ggagatgccg ttcgtccaca aatgctcaaa gaaagcgatg tggtcatcag
     1081 tgacttgcct gttggctatt atcctgatga tgccgttgcg tcgcgccatc aagttgcttc
     1141 tagccaagaa catacttacg cccatcactt gctcatggaa caagggctta agtacctcaa
     1201 gtcagacgga tacgctattt ttctagctcc gagtgatttg ttgaccagtc ctcaaagtga
     1261 tttgttaaaa gaatggctga aagaagaggc gagtctggtt gctatgatta gtctgcctga
     1321 aaatctcttt gctaatgcta aacaatctaa gactattttt atcctacaga agaaaagtga
     1381 aatagcagtg gagccttttg tttatccact tgctagcttg caagatgcaa gtgttttaat
     1441 gaaatttaaa gaaaattttc aaaaatggac tcaaggtact gaaatataaa atagattttg
     1501 ttataatagt tgaaaacgct taaaaagggg tatcatgtta tgacaaaaac aattgcaatc
     1561 aatgcaggaa gttcaagttt gaaatggcaa ttatacttaa tgccagagga aaaagtgtta
     1621 gccaaaggtt tgattgaacg tatcggtttg aaagattcaa tttcaactgt aaaatttgac
     1681 ggccgttctg aacaacaaat tttggatatc gaaaatcata cacaagctgt taaaatttta
     1741 ttggatgact tgattcgttt cgatattatc aaggcttatg acgagattac aggtgttggc
     1801 caccgtgttg tagcaggtgg agaatatttc aaagaatcaa cagttgttga gggagatgtt
     1861 ttagaaaaag ttgaagagtt gagtttgttg gctcctctac acaacccggc caatgcagca
     1921 ggtgttcgtg ctttcaagga attgttgcca gacattacca gtgtagttgt ttttgatact
     1981 tccttccaca caagtatgcc agagaaagct tatcgctacc ctctaccaac aaaatattac
     2041 acagaaaaca aggttcgtaa atacggtgct catggtacaa gtcaccagtt tgtagcagga
     2101 gaagctgcaa aactcttggg acgtccatta gaagacttga agttaattac ctgtcatatt
     2161 ggtaacggag gctcaattac agctgtgaaa gccggcaaat ctgtagacac ttctatgggg
     2221 ttcactcctc ttggtggtat tatgatggga acgcgtacag gggatattga tccagctatc
     2281 attccttatt taatgcaata tacagaggat tttaacacac cagaagatat cagtcgtgtt
     2341 cttaaccgtg aatcaggtct tttgggagtt tctgctaatt ctagcgatat gcgcgatata
     2401 gaagcagctg tagcagaagg gaatcacgag gctagcttgg cttatgaaat gtatgttgac
     2461 cgtatccaaa aacatatcgg tcagtacctt gcagtgctaa atggaacaga tgccattgtt
     2521 ttcacagcag gtgtcggtga aaatgcagag aatttccgtc gtgatgtaat ctcagggatt
     2581 tcgtggtttg gttgtgatgt tgatgatgaa aagaatgtct ttggcgttac aggagacatc
     2641 tcaacagagg cagctaaaat ccgtgtcttg gttattccaa cagatgaaga attagtcatt
     2701 gcccgtgacg ttgaacgctt gaaaaaataa gtgaaactaa aaaaatattc aatacaagga
     2761 gttgggaaag ttatttttcc agcttctttt tctgatgaaa ttgtccaaaa ccttgctatg
     2821 attggctttt ttgaaaaata tggtataata gtagtaattt aatagatgga gttgagtttt
     2881 gaagaaaaac tttcgtgtaa aaagagagaa agattttaag gcgattttca aggaggggac
     2941 aagttttgct aatcgcaaat ttgtggtcta ccaattagaa aaccagaaaa accattttcg
     3001 agtaggtcta tcagttagca aaaaactggg gaatgccgtc actagaaatc aaattaagcg
     3061 acggattcgg catattatcc agaatgcaaa agggagtctg gtagaagatg tcgactttgt
     3121 tgtcattgct cgaaaaggag tcgaaacctt gggatacgca gagatggaga aaaatctact
     3181 ccatgtatta aaattatcaa agatttaccg ggaaggaaat gggagtgaaa aagaaactaa
     3241 agttgactag tttgctagga ctgtctctgt taatcatgac agcctgtgcg actaatgggg
     3301 taactagcga tattacagcc gaatcggctg atttttggag taaattggtt tacttctttg
     3361 cgaaaatcat tcgcttttta tcgtttgata ttagtatcgg agtggggatt attctcttta
     3421 cggtcttgat tcgtacagtc ctcttgccag tctttcaggt gcaaatggtg gcttctagga
     3481 aaatgcagga agctcagcca cgcattaagg cgcttcgaga acaatatcca ggtcgagata
     3541 tggaaagcag aaccaaacta gagcaggaaa tgcgtaaagt atttaaagaa atgggtgtca
     3601 gacagtcaga ttctctttgg ccgattttga ttcagatgcc ggttattttg gccttgttcc
     3661 aagccctatc aagagttgac tttttaaaga caggtcattt cttatggatt aaccttggta
     3721 gtgtggatac aacccttgtt cttccgattt tagcagcagt attcaccttt ttaagtactt
     3781 ggttgtccaa caaagctttg tctgagcgaa atggcgctac gactgcgatg atgtatggga
     3841 ttccagtctt gatttttatc tttgcagttt atgcgccagg tggagtcgcc ctatactgga
     3901 cagtgtctaa tgcttatcaa gtcttgcaaa cctatttctt gaataatcca ttcaagatta
     3961 tcgcagagcg cgaggccgta gtacaggcac aaaaagattt ggaaaataga aaaagaaaag
     4021 ccaagaaaaa ggctcagaaa acgaaataaa taaggaggaa tctggtaatg gtagtattta
     4081 caggttcaac tgttgaagaa gcaatccaga aaggattgaa agaattagat attccaagaa
     4141 tgaaggctca tatcaaagtc atttctaggg agaaaaaagg ctttcttggt ctatttggta
     4201 aaaaaccagc ccaagtggat attgaagcga ttagtgaaac gactgttgtc aaagcaaatc
     4261 aacaggtagt aaaaggcgtt ccgaaaaaaa tcaatgattt gaacgagcct gtgaagacgg
     4321 ttagtgaaga aaccgttgac cttggtcatg tggttgatgc tattaaaaaa atagaggaag
     4381 aaggtcaagg tatttctgat gaagtcaagg ctgaaatctt aaaacatgaa agacatgcca
     4441 gcactatctt agaagaaact ggtcacattg agattttaaa tgaacttcaa atcgaggaag
     4501 cgatgaggga agaagcaggc gctgatgacc ttgaaactga gcaagatcaa actgaaaatc
     4561 aagacttgaa agagatgggc ttgaaggtcg agcaaagtta tgatattgcc caggtggcta
     4621 cggatgtgac tgcctatgtt caagcgattg tggatgacat ggatgttgaa gctacacttt
     4681 caaatgatta taaccgtcgt agcatcaatc tacaaattga caccaacgaa ccaggtcgta
     4741 ttatcggcta ccatggtaaa gtcttgaagg ccttgcaact gttggctcaa aattatcttt
     4801 acaaccgcta ttccaaaacc ttctacgtta caatcaatgt caatgattat gtcgaacacc
     4861 gtgcagaagt cttgcagacc tatgcgcaaa aattggcgat tcgtgtttta gaagaaggac
     4921 gtagtcatca aacagatcca atgtcgaata gtgaacgcaa gattatccac cgtattattt
     4981 cacgtatgga tggcgtgacc agttactctg aaggtgatga gccaaatcgc tatgtcgttg
     5041 tagatacaga ataagtaaaa tcagggttga cctgattttt tgctagctag aggaggttaa
     5101 actaatgttg aataagataa gagactattt agactttgct ggtttgcagt accgtaatcc
     5161 tgataaagcg ggagcagagc gagagaagat gctggcattc cgccacaaag gacaagaggc
     5221 ccgaaaggct tttacagaac tggccaaagc ctttcaagca agccatccag gatggcaact
     5281 ccaacagact agtcagtgga tgaatcaggc ccagcgtttg agaccacatt tttgggttta
     5341 tctacagaga gacgaacaag tgacagaacc tatgatggcc ttacgtttgt atgggacatc
     5401 tactgacttt ggaatttctt tggaagtcag tttcatcgaa cgtaagaagg atgagcaaac
     5461 actgggcaag caggccaaag ttttagacat tccaaccgtt aaagggattt attatctaac
     5521 ctactctaat ggtcaaagtc aacggtggga ggcgaatgaa gaaaagcgtc gtactttacg
     5581 cgagaaggtg agaagtcaag aagttcgaaa agttttagtg aaggtagatg ttcctatgac
     5641 agaaaattcg tctgaagaag aaatcgtaga aggcttattg aagtcttatt ctaaaattct
     5701 tccctattat ctagctacga gaaaataaga taatttgtaa aacatcataa atcatacagt
     5761 ccaagagtga acagtccgct gtgtaattct tggtcttttt gtttgcgctt tcgcattata
     5821 taataaactt acaaaaacaa ttcaaaagga gaacaattat ggaagtcgtt tcaagtgttc
     5881 taaattggtt ttctagcaat attttgcaga atcccgcatt tttcgtaggt ttattggtgt
     5941 tgataggata tgcacttttg aaaaaacctg cccatgacgt tttttcaggg tttgttaaag
     6001 caacagtagg gtatatgttg cttaacgtgg gtgctggtgg tttggttaca acctttcgtc
     6061 caatcttagc agctcttaac tacaaattcc aaattggtgc agcggttatc gacccttact
     6121 ttggacttgc tgcagcaaac aacaaaattg cagcagagtt tccagatttt gttggaactg
     6181 caactacagc tctattgatt ggttttggaa taaatatctt gctcgtagct cttcgaaaga
     6241 ttacgaaggt aagaaccctc tttattactg gtcacatcat ggtacaacaa gctgcaacag
     6301 tatctcttat ggttctattc ttagtaccac aattgcgcaa tgcttacggt acagcagcga
     6361 ttggtatcat ctgtggactt tactgggcag ttagttcaaa tatgactgtt gaggcaactc
     6421 aacgcttgac tggtggtggc ggatttgcga ttggtcacca acagcaattt gcaatctggt
     6481 ttgtagataa agtagcagga cgctttggta agaaagaaga aagtttagac aatcttaaat
     6541 tacctaagtt cctctcaatc ttccacgata cagttgttgc atctgctacc ttgatgctcg
     6601 tattcttcgg agccattctt ttaatcttgg gtccagacat tatgtctaat aaagaagtca
     6661 tcacttcagg aactctattc aatcctgcta aacaagattt ctttatgtac attatccaaa
     6721 cagcctttac cttctcagtt tacttgttcg ttttgatgca aggtgtccga atgttcgtat
     6781 ctgagttgac aaacgccttc caaggtattt caaacaaatt gttgccaggt tcattcccag
     6841 cggttgacgt tgcagcttct tatggatttg gttctccaaa tgctgtcttg tcaggattta
     6901 cctttggttt gattggtcaa ttgattacaa ttgttttgct catcgtcttt aaaaatccga
     6961 ttcttattat tacaggattt gtaccagtgt tctttgacaa tgcagccatt gcggtctacg
     7021 ctgataaacg cggcggatgg aaagcggctg ttatcctttc ctttatatca ggtgtccttc
     7081 aagttgctct aggagctctt tgtgtggccc ttctcgattt ggcatcttat ggtggctacc
     7141 atggaaatat cgactttgaa ttcccatggc ttggatttgg atatatcttc aaataccttg
     7201 gtattgttgg ttatgtactt gtgtgtctct tcttgcttgt tattcctcaa cttcaatttg
     7261 ccaaagcaaa agataaagag aaatattaca acggtgaagt tcaagaagaa gcttagtatc
     7321 tagaaaagga gaaataaaat ggttaaagta ttagcagcgt gcggaaatgg aatgggttca
     7381 tcaatggtta tcaagatgaa ggttgaaaat gctctccgta agcttaatca aacagatttt
     7441 acagtcaatt catgcagtgt cggtgaagct aaaggtttag cagtaggata tgacattgta
     7501 atcgcttctc ttcatttgat tcaagaattg gaagggcgaa ctaatgggaa gttaattggg
     7561 cttgataact tgatggatga taaagaaatc accgaaaaac tcagtcaagc actacagtaa
     7621 aaggttggag ggggctggac agaaactgag agttatcgtt tctgtccagc cccctcttta
     7681 aataaaggag gcagatatga atttaaaaca agctttaatt gacaatgact cgatccgact
     7741 aggtttagag gctaacaatt ggaaagaagc agtcaaggta gcagtagatc ccttgattga
     7801 aagtggggca attttgccag agtattacga tgctatcatt gaatcgactg aagagtatgg
     7861 gccttactat atcttgatgc caggtatggc tatgccccac gctagacctg aagctggtgt
     7921 gcaaagtgat gccttttcat tgattacctt acaaaatcct gttgtatttt cagatgggaa
     7981 agaggtatct gttttgttgg cactagcagc aacaagttca aaaattcaca caagtgtagc
     8041 cattccacaa attattgccc tgtttgaatt agaagattct attgcacgtt tacaggcttg
     8101 ccagactaaa gaagatgtct tggctatgat tgaagaatct aaggatagcc cttatctcga
     8161 aggattggat ttggaaagtt agaaagagga ataaagaaat gacaaaaaga atacctaatt
     8221 tacaagttgc attagaccat tcagacttgc aaggagcgat taaagcagct gtttctgttg
     8281 gtcaggaagt agatattatc gaagctggaa ctgtttgctt gcttcaagtt ggaagtgaac
     8341 tggctgaagt cttgcgtagc cttttcccag ataagattat tgtggcagac acaaaatgtg
     8401 ctgatgctgg tggaacagtt gctaaaaata atgcggttcg tggagcagac tggatgactt
     8461 gtatctgttg tgcaaccatc cctactatgg aagcagctct aaaggctatc aagactgaac
     8521 gaggagaacg aggcgaaatc cagatcgagc tttatggcga ttggactttt gaacaagctc
     8581 agctttggct agatgcaggt atctcacaag ctatttatca ccaatctcgt gatgctcttc
     8641 ttgctggtga aacttggggt gaaaaagacc ttaataaggt taaaaaactc attgacatgg
     8701 gcttccgtgt atctgtaaca ggtggtctag atgtagatac tctcaaactc tttgaaggtg
     8761 ttgatgtctt tacctttatc gcaggtcgtg gaattacaga ggctgcggat ccagcaggag
     8821 cagcgcgtgc cttcaaggat gaaatcaaac gaatttgggg gtaaatcatg gtacgtccaa
     8881 ttggaattta tgaaaaggca accccaacac actttacttg gctagaacgt ttaaattttg
     8941 ccaaggagtt aggctttgat tttgtcgaga tgtctattga cgaacgtgac gagcgtttag
     9001 caagacttga ctggagtaag gaagaacgct tggaagttgt caaagaaatc tatgaaactg
     9061 gtgttcgtat tccttctatc tgtttttcag gccatcgtcg ctacccattg ggttcaaaag
     9121 atccagttct agaggaaaaa tctctagaac tcatgaaaaa atgtatcgaa ttagctcaag
     9181 acttgggagt tcgtacgatt caattagctg gttacgatgt ttactatgag gaaaagtcac
     9241 cccagacacg ccaacgtttt atcaaaaatt tgagaaaagc ctgtgactgg gctgaagaag
     9301 ctcaggtggt acttgctatt gaaattatgg atgatccttt catcaatagc atcgaaaaat
     9361 atttggctat agaaaaagag attgactctc ccttcctctt tgtatatcca gatattggta
     9421 atgtgtctgc atggcataat gatatctata gtgagtttta tcttggtcat catgccatcg
     9481 cagctctcca tctcaaggat acttatgcag tgacagaaag ttcaaggggc cagttccgag
     9541 atgtaccttt tgggcaaggt tgtgtcaaat gggaagaagc tttcgatatt ttaaaggaaa
     9601 ccaattataa tggacctttc ctaatcgaaa tgtggtctga aaattgtgaa acagtagaag
     9661 aaacacgcgc agccattcaa gaggcgcaag cttttctcta tccactcatt aagaaagcag
     9721 gtttgatgta agatgaatca agtaatcaat gctatgcgta aacgagtctg tgatgccaat
     9781 caatcattgc caaaacatgg acttgtcaaa tttacctggg ggaatgtatc tgaagtcaat
     9841 cgcgaactcg gtgtcattgt tatcaaacca tcaggcgtgg attatgacga attgacacct
     9901 gaaaacatgg tagtgactga tctagatggt aagatcctag aaggggattt aagaccatct
     9961 tccgacctcc caactcatgt gcaattatat aaggcttggt cagaaattgg tagtgtggtt
    10021 cacacccatt cgacagaagc tgttgcttgg gctcaggcag gtcgtgatat tcctttctac
    10081 ggaacaaccc atgcagatta tttctacggt tcaatccctt gcgcccgtag tttgaccaag
    10141 gacgaagtag aagtggccta tgaaaaagat actggcctgg ttatcgtaga agagtttgaa
    10201 catcgcggac ttaacccggt tgaagtacca ggaattgttg tacgcaatca cggtccattc
    10261 acctggggca aaaatccaga gaatgctgtt tatcactctg tcgtactaga ggaagtatca
    10321 aagatgaatc gctttacaga acaaatcaat ccaagagttg gacctgctcc ccagtacata
    10381 ctagaaaaac actaccaacg taaacatgga ccaaatgctt attatggtca aaagtaagaa
    10441 cgatgaagga ggagaaaaag ataaatttag ctcctctttt tacatttgat ttttattgag
    10501 agtaaagttg gagttgaagt aattttaaaa gattttttag aaatagcgct tgatatatat
    10561 atggtaaaat aaaaagaatt gctgtgatat caatagattt gggggatttt ttaatatggt
    10621 actggataag gcaagttgtg atttgcttca atatttgatg gatcaagaaa cgtccaaaac
    10681 gattatggcg atttcgaaag atttgaaaga gtcaagaagg aaaatttatt atcacattga
    10741 caaaatcaat gctgctctgg gtgacgaggc gcttcacatc attagtattc cacgaattgg
    10801 tattcactta acggaagagc agagagatgc ttgttgtaaa ctattatcgg aagtagattc
    10861 gtacgattat atcatgagtg cgcatgaacg tatgatgata atgttactat ggataggtat
    10921 ttctaaagaa cgtattacga ttgaaaaatt gatagagtta acagaggtat ctaggaatac
    10981 tgttctcaat gatttgaata gtattcgtta tcaactaact ttggaacaat atcaggtgat
    11041 cttgcaagtg agcaagtcac agggatacca ccttcatgcc caccctctta ataaaattca
    11101 gtatcttcaa tcgcttctat atcatatttt tatggaagaa aatgccactt ttgtatctat
    11161 tttagaagat aagatgaaag agaggttaga tgatgagtgt ttgctttctg ttgaaatgaa
    11221 ccaatttttt aaggaacagg ttcctttagt tgaacaagat ttagggaaga aaataaacca
    11281 tcatgaaata acttttatgt tgcaggttct accttatttg ctgttaagct gtcataatgt
    11341 tgaacagtat caagaaagac atcaggatat agagaaagaa ttttctttga taagaaaaag
    11401 aatagagtat caggtgtcta agaaattagg agaacggttg tttcaaaagt ttgaaatttc
    11461 tttgtcagga cttgaagttt ctcttgtagc tgttctcctc ctctcctatc gtaaagattt
    11521 ggatattcat gcagaaagtg atgattttcg gcaattaaaa cttgctttag aagaatttat
    11581 ctggtatttt gaatcacaaa tccgaatgga gattgagaac aaggatgatt tgttacgaaa
    11641 tttgatgatc cactgtaaag ccttgttatt tagaaagact tacggtattt tttctaaaaa
    11701 tcctctaaca aaacaaattc gatccaagta tggagaatta tttttagtca ctagaaaatc
    11761 tgcggaaatt ttagaaggag catggtttat tcggctaaca gacgatgata ttgcctattt
    11821 gacgattcat attggaggat ttttaaaata tacaccatca tctcaaaaaa atatgaaaaa
    11881 agtttatctc gtttgtgatg aaggtgttgc ggtttcgaga cttttgctga aacaatgcaa
    11941 actttatttt ccaaatgagc aaattgacac tgtatttaca acagaacaat ttaagagtgt
    12001 ggaagatatt gcacaagttg atgtagtgat tactactaat gatgatttgg atagcagatt
    12061 tccgatttta agggttaatc ctatccttga agcagaagat attttgaaaa tgctagacta
    12121 tcttaaacac aatatatttc gtaataagag caaaagtttc agtgaaaatc tttctagtct
    12181 tatttcgtct tatattgtag acagcaagtt ggctagtaag ttccaagaag aggttcaaac
    12241 acttataaat caagaaatag tagttcaagc ttttttggaa gatatttgaa ggacagtcca
    12301 atgatgaaca caaacctgtg tttttcttgg tcttttttag tgttttgaag ggtggtatac
    12361 taatctcaaa gataacaatt atatccaaag gaggcaacat atgccaaacg tcaaagaaat
    12421 tacaagagag tcatggattt tagccacttt cccagagtgg ggaacatggt tgaacgaaga
    12481 aatcgaagaa gaagtcgtac ctgaaggcaa ctttgccatg tggtggctag gcaactgtgg
    12541 tacttggatt aagacaccag ctggtgctaa cgttgtcatg gacctttggt caaaccgtgg
    12601 aaaatcaacc aaaaaagtga aagatatggt tcgtgggcac caaatggcaa atatggcagg
    12661 tgttcgtaag ctgcaaccaa acttgcgtgt tcagccaatg gttatcgatc catttgctat
    12721 caacgaacta gactattact tagtttcaca cttccacagt gatcatatcg acccatacac
    12781 agctgcagca attctcaata atcctaagtt agagcatgtt aagtttatcg gtccttacca
    12841 ctgtggacga atctgggaag gatggggtgt tccaaaagaa cgtatcatcg ttgttaaacc
    12901 aggtgacact atcgaattaa aagatatgaa gattcatgca gtagaatcat ttgaccgtac
    12961 ttgcttggta actctcccag tgaacggtgc tgatgagaca ggcggtgaac ttgctggctt
    13021 ggctgttaca gatgaagaaa tggctcaaaa ggctgttaac tatatctttg aaacaccagg
    13081 tggaaccatc tatcatggtg cagattctca cttctcaaac tattttgcaa aacatggtaa
    13141 agactttaaa attgatgttg ctttgaataa ctatggtgaa aatccggtag gtatccaaga
    13201 caaaatgaca tctatcgacc ttcttcgtat ggcagaaaat ctgcgtacca aagtcattat
    13261 cccagttcac tatgatatct ggtctaactt catggcttct actaatgaga ttctagaact
    13321 ttggaaaatg cgaaaagatc gcttgcaata cgatttccat ccatttatct gggaagttgg
    13381 cggtaagtac acttatcctc aagatcaaca cttagtagaa taccatcatc cacgtggttt
    13441 tgatgattgt tttgaacaag actctaacat tcaatttaaa gctttgctat aatataaaaa
    13501 tattctttgg aggttatccg tatgttgcat gatacggata attttcatat aatagtaaaa
    13561 tagaatgtgt gattcaataa tcacctcaaa tagaaaggaa attctatgtc aaatctatct
    13621 gttaatgcaa ttcgttttct aggtattgac gccattaata aagccaactc aggtcatcca
    13681 ggtgtggtta tgggagcggc tccgatggct tacagcctct ttacaaaaca acttcatatc
    13741 aatccagctc aaccaaactg gattaaccgc gaccgcttta ttctttcagc aggtcatggt
    13801 tcaatgctcc tttatgctct tcttcacctt tctggttttg aagatgtcag catggatgag
    13861 attaagagtt tccgtcaatg gggttcaaaa acaccaggtc acccagaatt tggtcatacg
    13921 gcagggattg atgctacgac aggtcctcta gggcaaggga tttcaactgc tactggtttt
    13981 gcccaagcag aacgtttctt ggcagccaaa tataaccgtg aaggttacaa tatctttgac
    14041 cactatactt acgttatctg tggagacgga gacttgatgg aaggtgtctc aagcgaggca
    14101 gcttcatacg caggcttgca aaaacttgat aagttggttg ttctttatga ttcaaatgat
    14161 atcaacttgg atggtgagac aaaggattcc tttacagaaa gtgttcgtga ccgttacaat
    14221 gcctacggtt ggcatactgc cttggttgaa aatggaacag acttggaagc catccatgct
    14281 gctatcgaaa cagcaaaagc ttcaggcaag ccatctttga ttgaagtgaa gacggttatt
    14341 ggatacggtt ctccaaacaa acaaggaact aatgctgtac acggcgcccc tcttggagca
    14401 gatgaaactg catcaactcg tcaagccctc ggttgggact acgaaccatt tgaaattcca
    14461 gaacaagtat atgctgattt caaagaacat gttgcagacc gtggcgcatc agcttatcaa
    14521 gcttggacta aattagttac agattataaa gaagctcatc cagaactggc tgcagaagta
    14581 gaagccatca tcgacggacg tgatccagtc gaagtgactc cagcagactt cccagcttta
    14641 gaaaatggtt tttctcaagc aactcgtaat tcaagtcaag atgccttgaa tgttgtggca
    14701 gctaaattac caacctttct aggtggatca gctgaccttg ctcactcaaa catgacttat
    14761 atcaagacgg atggacttca agacgatgcc aatcgcttga atcgtaacat tcagtttggt
    14821 gttcgtgaat ttgcaatggg aacaatcttg aacgggatgg cccttcatgg tggacttcgt
    14881 gtatacggtg gaactttctt cgtcttctct gactatgtga aggcagctgt ccgcttgtca
    14941 gccttacaag gacttcctgt gacttatgtc tttacccatg attcaatcgc agttggggaa
    15001 gatggtccga ctcatgaacc agttgagcat ttagcaggtc ttcgtgctat gccaaatcta
    15061 aatgttttcc gtccagcaga tgcgcgtgaa acgcaagcag cttggtacct tgcagtgaca
    15121 agtgagaaaa caccaactgc ccttgtcttg acacgtcaaa atttgactgt tgaagatgga
    15181 acagacttcg acaaggttgc taaaggtgct tatgttgtat atgaaaatgc agccgacttt
    15241 gataccatct tgattgcgac aggttcagag gttaatcttg ctgtctcagc tgctaaagaa
    15301 ttggctagtc aaggcgaaaa aatccgcgta gtcagcatgc catctacaga tgtctttgat
    15361 aaacaagatg cagcttacaa ggaagaaatt cttccaaatg cagtccgccg tcgtgttgca
    15421 gtcgaaatgg gtgcaagtca aaactggtac aaatatgttg gtctcgatgg tgccgttcta
    15481 ggtattgata ccttcggagc ctctgcccca gcaccaaaag tattggcaga atatggcttt
    15541 actgtagaaa atcttgtaaa agttgttcga aacttgaaat aatcctaaaa atcagggcgt
    15601 aagctctggt ttttcttacc agaaaagtaa ggtacaatct tgtaaaagta gctgaaattt
    15661 gatatagtag tcctatgtaa aagacaaagg agaaaacaat gaatccaaat attacttttt
    15721 taatcatgct tgtaggtatg atggccttga tgttctttat gcaacgttct caaaagaaac
    15781 aagctcaaaa gcgtatggaa agcttaaata aactacaaaa aggctatgaa gtgattacaa
    15841 tcggtggact ttatggaaca gtcgatgaag tagatacgga gaagggaaca atagttcttg
    15901 acgtagaggg agtttacttg acttttgaac tagctgctat caagacagta ttaccgctga
    15961 aagaaacagc ttcactagaa ggcgcaattg aaaaataaga cgggatcacg aactcccgtt
    16021 tttctataaa agaaaggaaa tgggatgaaa aaattagtct ttgtctgtct gggaaatatt
    16081 tgccgtagcc ctatggccga gtttgttatg aaatcaatga cagataacta cgaaatccaa
    16141 agtcgagcaa cttcctcttg ggaacatggc aatccgattc ataaggggac tcagggaatt
    16201 tttcaagagt atgagattcc ttatgacaag aacaagacat cgcttcagat tagtaaggaa
    16261 gattttgaag cctttgatta tattatcgga atggacgctt caaatatttc tgacttacgt
    16321 cagatgtgtc cagtagactg tcaagataag atttactcat tttcatctga aagtgttcca
    16381 gacccttggt atacaggaga ttttgaagaa acctatcgac gtgttcaaga gggctgtcaa
    16441 gcttggttag aacgtttaga aaaggagagt taaggtggaa aatcttacga atttttacga
    16501 aaagtatcgt gtctatctga ctcgtccacg tttagagctt ttggcagtag ttaccattgt
    16561 tttctgtgct gtactcgtct tttttctaaa tattccagga aaaggtgtct taaaactcga
    16621 taatggaacg attgtttatg atggcagtct tgtccgcggt aaaatgaatg gccaaggtac
    16681 cattaccttc caaaatggag accaatatac aggtggcttc aacaatggag ccttcaacgg
    16741 aaaaggtacc tttcaatcta aagaaggctg gacctacgaa ggtgattttg taaatggtca
    16801 ggctgaagga aaagggaaac taacaacaga acaagaagtc gtttatgaag gaacttttaa
    16861 acaaggcgtt tttcaacaaa aataaagcct ccttatcaaa ggaggtatta ttagaatcgc
    16921 aaggtaagcg cttacctgca aatccctttc tttccaaatc cctcttccaa gcaagtttgt
    16981 gaaataaaaa atatttgaaa taaatttcac aaacttcaaa gataaaacct gataagaaaa
    17041 gaaaatgaga aaagtttcac aagagtttaa aaattctttg tgaaatgttt atgaaactgt
    17101 ttacaaagtt gaaataatgc gttataataa acttgtgaaa aaattaacaa aggatatcgt
    17161 tccttgaaag ctatggagga aaatatggct gataaaaaaa ctgtgacacc agaggaaaag
    17221 aaactcgttg ctgaaaaaca cgtagatgag ttggttcaaa aagctctagt tgcccttgaa
    17281 gaaatgcgta aattggatca agaacaagtt gactacatcg ttgccaaagc atcagtagca
    17341 gctttggatg cccacggaga attggcttta catgcctttg aagaaacagg acgtggtgta
    17401 tttgaagata aagcaactaa gaacttgttt gcttgtgaac acgtggtaaa caacatgcgt
    17461 cacactaaaa cagttggcgt tatcgaagaa gatgatgtaa caggattgac cctgattgct
    17521 gaaccagttg gtgttgtttg tggtatcact ccaacaacaa acccaacatc aacagcgatc
    17581 ttcaaatcat tgatttcatt gaagacacgt aatccaatcg tctttgcctt ccatccatca
    17641 gctcaagaat catcagctca tgcagctcgt atcgtccgcg atgcagctat cgcagctggt
    17701 gctcctgaaa actgtgtaca gtggatcact gaaccatcta tggaagcaac tagtgccctt
    17761 atgaaccacg aaggtattgc aacaatcctt gcaacaggtg gtaatgccat ggttaaagcc
    17821 gcatactcat gtggtaaacc agctcttggg gtaggtgccg gaaacgttcc agcttatgtt
    17881 gaaaaatcag caaacattcg tcaagcagca cacgatatcg tcatgtctaa atcatttgat
    17941 aacggtatgg tctgtgcatc tgaacaagca gttatcattg ataaagaaat ttacgatgaa
    18001 tttgtagcag agttcaaatc ttaccacact tactttgtaa acaaaaaaga aaaagctctt
    18061 cttgaagagt tctgcttcgg cgtcaaagca aacagcaaaa actgtgctgg tgcaaaattg
    18121 aacgctgaca tcgttggtaa accagcaact tggattgcag aacaagcagg atttacagtt
    18181 ccagaaggaa caaacattct tgctgcagaa tgtaaagaag ttggcgaaaa tgagccattg
    18241 actcgtgaaa aattgtcacc agttattgca gttttgaaat ctgaaagccg tgaagatggt
    18301 attactaagg ctcgtcaaat ggttgaattt aacggtcttg gacactcagc agctatccac
    18361 acagctgacg aagaattgac taaagaattt ggtaaagctg ttaaagctat tcgtgttatc
    18421 tgtaactcac cttctacttt tggtggtatc ggggacgttt acaatgcctt cttgccatca
    18481 ttgacacttg gatgtggttc ttacggacgc aactcagttg gggataacgt tagtgccatt
    18541 aacctcttga atatcaaaaa agtcggaaga cggagaaata acatgcaatg gatgaaactt
    18601 ccttcaaaaa catactttga acgtgattca attcaatacc ttcaaaaatg tcgtgacgtt
    18661 gaacgtgtca tgatcgttac tgaccatgcc atggtagagc ttggtttcct tgatcgtatc
    18721 atcgaacaac tggaccttcg tcgcaataag gttgtttacc aaatctttgc ggatgtagaa
    18781 ccggatccag atatcacaac tgtaaaccgt ggtactgaga ttatgcgtgc cttcaaacca
    18841 gataccatca tcgcactcgg tggtgggtct ccaatggatg ctgccaaagt aatgtggctc
    18901 ttctacgagc aaccagaagt ggacttccgt gaccttgtcc aaaaattcat ggatatccgt
    18961 aaacgtgcct tcaagttccc attgcttggt aagaagacta aattcatcgc gattccaact
    19021 acatctggta caggatctga agtaacacca tttgccgtta tctctgataa agcaaacaac
    19081 cgtaaatacc caatcgctga ctactcattg acaccaactg tggcaatcgt agatcctgct
    19141 ttggtattga cagttccagg atttgttgct gctgatactg gtatggacgt attgactcac
    19201 gcgacagaag catacgtatc acaaatggct agtgactaca ctgatggttt agcacttcaa
    19261 gccattaaat tggtctttga aaatctcgaa agctcagtta agaatgcaga cttccactca
    19321 cgtgagaaaa tgcataacgc ttcaacaatc gctggtatgg cctttgccaa tgccttccta
    19381 ggtatttctc actcaatggc ccataagatt ggtgcgcaat tccacacaat ccacggtcgt
    19441 acaaatgcta tcttgcttcc atacgttatc cgttacaacg gtacacgtcc agctaagaca
    19501 gcaacatggc ctaagtacaa ctactaccgt gcagatgaaa aataccaaga tatcgcacgc
    19561 atgcttggac ttccagcttc tactccagaa gaaggggttg aatcttacgc aaaagctgtc
    19621 tacgaactcg gtgaacgtat tgggatccaa atgaatttta gagaccaagg aattgacgaa
    19681 aaagaatgga aagaacattc tcgtgaatta gccttcctgg cttatgaaga ccaatgttca
    19741 ccagctaacc cacgtcttcc aatggtagac catatgcaag aaatcatcga agatgcatac
    19801 tatggctaca aagaaagacc aggacgccgt aaataattgt ttatcagtct agaagcaaga
    19861 caaaaactca atttgaggga aagatccagt aatttttcta tgataaaagg catcctatca
    19921 aggtttttga acacctgata ggatgccttt ttatgatatt gaggcctttt tgcccttttt
    19981 gaaaaactag aatagaaaca aaatatataa tagattgaaa ctggaatagt acacttctgc
    20041 ttctaaaaca ttgttagaat tcgatttgac tgtcctgatc gatttgtcct attcctattt
    20101 cattttacta tataaaaaat atagtatagt agactgaatc taaaatagta cgaaacaatt
    20161 gctaaaacat ttatagaaat taattttact ttcctgatag agttgttcac atcttatttc
    20221 aattcactat agtttaattt aagagtagta tttactaagg cccaattaaa atcaaagagc
    20281 aaactagaaa acgagtgcca ttcagctcaa aacactgatt tgagattgca gataagacta
    20341 gcccctcatt aacaggttta cgataaaacg atgacaaggt gtgttgcttt ttgatttcta
    20401 aagagtataa tgatagatct ctataaaata agtgcgaagg aaatgagctt ttatagtcct
    20461 ttcgttttaa aatactatct cagatgttct tatatcgaca agaagttttt gagtcattcc
    20521 ctcatcatac atattaaata aatagtggct cattcaattt tttactagaa taataagcta
    20581 gtatagtaaa ctgaaataag atataaacaa ataaattgga gcttaacatc tatttccagc
    20641 aattttttag aaactgcagt ggactattct aaattcaaca cattataaaa actagagtaa
    20701 aagaaaagga ttggatcttg tgtaatgcag gatctaatcc tttcaatcat tttgtccaac
    20761 ttttggaggt tcctacaatg tagccgtcat taataaagac agatgggaac gacagtgttc
    20821 ctatttattt tgatagagat cgatgaattc tttagatagc aactgaataa tctctgttga
    20881 agccatttgg tcttctgcat gcataaatag caaggagaat cctatttttt ctccagtagc
    20941 ttctttttgt atgagattag agtgaatctt gtgcgcttct actaaggagt cttccgcttc
    21001 ttcaacttta attttcgctt cttttaaatt tcctgcctta gctagttgga tggcttcaat
    21061 aaaggatgat ttggctgctc cactattggc aatgagctga aaacagatat attccatttc
    21121 ttctgtcatc ttatttctcc tatccatgca agtgcttgtt ccagaacttt tgctccattc
    21181 atcattccgt aatcccgcat atcaatggta tctacaggga tatttcctgc aatttctttc
    21241 acagcaagta actcataacg aatttgtggc ccaattagaa tgacatctgc ttcatggata
    21301 ttctttttcg cttctgtcat tgattttgct tggatagaaa tttcaatccc acgttcagtc
    21361 gcactttgtt gcattttttt aacaagcata cttgtcgaca ttcccgcatt acatactaat
    21421 aaaatttgtt tcataatctt aaccttccat ttcttgctca acaactttgt cattaacttt
    21481 gataaatgga atgtatagaa gaactccaag tgcaaagatg atgaattgaa ctagaactgc
    21541 tctcacgtcc cctgctgttg ctaaccatgc atttaagaat actggtgtag tccaaggaac
    21601 ttgtataaat gcaggactca tgaatcctgt aactgttgct aagtagctga ttaaaatacc
    21661 aaggactgga actgtgataa atggaatagc taatgaaatg ttataaacga ttgggtaacc
    21721 gaataatact ggttcattga tattgaagat accaggtcca aaagataatt tagccacgtt
    21781 tttagaaaca gcattgcgac tcactaagaa tgttgctatt aataaacata atgtagatcc
    21841 actaccaccc attaaagcga atgtttgtat ttgtgataag ttgatgatgt gtggaatggc
    21901 ttgtccatta tttgctgcag tgatgttttc agtaatgtta attaatagta atggttctag
    21961 gatggcactg taaataactg cttggtgaat accaaatagc cataacatat ttcctaaaga
    22021 gtaaataata atgaccccga ttaagcttgt accaatatga cgaattggtt cttgaataaa
    22081 gattgtaatg attgagatta agttcattcc agttatattg aataataatg ctgaaacaat
    22141 cccaaataag gagatgacag tcatgactgg aagtaatacg ctaaatgatc tactaacagc
    22201 tggtggaata ttttcaccaa ggttcatttg taaagcttta acgtttgata attcaatgaa
    22261 taattctgtt gcaataatcg ctacgataac cccggcgaac attgcgcctg tacctgtgtt
    22321 gttgaatgaa agaacacctg aaatgtttac agcatctttt gctccgtcag gaactacaga
    22381 aactgtattt ggcatcatca caattaaaga aactaatgat agcattgatg ctgctgacgg
    22441 gttttcgaaa tctctgtttt tagctaagaa ataaccaacc attacagcaa taatcatacc
    22501 tgaaatactt aaagtaccgt ttgcaattgt tattccccaa tattggaatt ttgttaatgt
    22561 atccccttgg aaaatccact taaataccgt gttgttcaaa agaacgatta aacctgccaa
    22621 aatatataat ggcattactg ttacgaatgc atctcttagg gtttttaaat gaatttggtt
    22681 ccctagttta ccagcaaagg tggcaaattg atctataaat tttgagtttt tcatctgaat
    22741 atctcctctc tttactcctc aatttctact tcaaaaccgt tattgtcact tactttgcga
    22801 taccatcttc ctgagctctt gatggttctc ttttgcgttt ctaaatcaac ggagataaat
    22861 ccgtaacgat tcttatatgc attattccaa gaccagcaat caaatgcggt ccaagcgtgg
    22921 tatccaaaac agagacttcc ctcttcaatg gctttatgta gccatcttaa atgttcttca
    22981 taaaattcaa tacgatacac gtcatcgata actccatttt catcgataaa ccgtgcttcg
    23041 ttttcaacac ccattccgtt ctcactgata aaccatggga tattaccata ttcttccttc
    23101 acaatcatag caatatcata aatggctttc ggaaaaattt cccaaccacg atatggattc
    23161 atgcgacgct ccggccattc atactctttg aagtattggt ctggcatcca gggcgtctga
    23221 tattcctcag gatttgcttg tgcttgaaca cgttttggat ggtagtagtt tactccaaga
    23281 aaatcaaccg tatttgattt catcagttga agctcttttt cggtatgact ccataacacg
    23341 ccatctctct ctagctgttt taccaatctt tctgggaaag ttcctttaac agctggattc
    23401 aagaagactt tgttaaagaa gtcttctgta aatcgacttg cttctaagtc ttctggagaa
    23461 ttacttcttg gataagcagg tgtcaagttt aaaataatcc caatctttcc atcaagtcct
    23521 aatgagcgat atagttgaat cacttttgca ctagcaaggt ttagattata gatgacttgt
    23581 acggcctctt ttccctttcc ttttagattt ggataatgga aagcatataa gtatcctgct
    23641 tctggaatga ccattggctc attgaaagtt gtccagtaat gaaccttatc tccaaagcat
    23701 gtgaaagcag tcttggcaaa cttcacgaat aactccacta catgtttgct ttcccaacca
    23761 ccgtattttt gaagaagttc cactggtaaa tcaaaatgat gtaaattcat cacaagatcc
    23821 atctggttct ttttagcttc ttcaatgatg gcattgtaga aagcaatacc ttttggatca
    23881 ggctcacctg tctctaaatt cttgatgagt cgactccatt ggatggaagt gcggaaagaa
    23941 ttaactccaa tttccttcat caagtggaaa tcttcggtgt aagtatgaaa aaagttactg
    24001 gctacaagag gtccgacatt atcgaaaaaa tcttctggat gcgttttgaa ccagtagtcc
    24061 atcacatttt catgtacttt tccatattga ccttctgtct gaggtccgct agaagcagct
    24121 ccccaccaaa acagattagg aaatactaac ttttttttca tgctcaacct cctttctatt
    24181 atgctataca taaagtatag cataatttta aaatttgtct agacattttt aaaaattgtt
    24241 gatacatata ttgtgtttgc ctcatttctt gaactttgtt atactactat tagaatatta
    24301 tagagagaac cagattaaat gagtacaaaa tatttattta tttacaatga gattcgtgaa
    24361 aagattctct gtaataaata taccatgaac gaacaattgc ctgatgaaat gacattagct
    24421 aaacagtttg cctgtagtcg aatgacgatc aaaaaagctt tagacttgtt agtttctgag
    24481 ggcttaattt ttagaaaacg tgggcaggga acctttgttc tctctcgtgg cagctcaaaa
    24541 agaaaattaa tcgttccaga aagagatatc cggggactga caaaaatatc tgaagatgct
    24601 cattctacaa ttgactcgag gattattcac ttcaaattag aatttgcaaa tgaattttta
    24661 gcagaaaaac tacaggtcgc tttgcagagt ccagtttata atatttaccg cctgcgtatt
    24721 attgacggta aaccttatgt tctggaacaa acttatatga gtaccgatgt tattccaggt
    24781 attactgaag atattttaca aaaatcgatt tacaattaca ttgaaggaaa gttaggattg
    24841 catattgcca gtgctacaaa aatcttgcga gcttcttcta gttcagaaaa tgagcaacat
    24901 tacttgcagc tccttccaac agaaccggta tttgaagtag aacaagtggc ttatttggat
    24961 aacggaactc cgtttgagta ctcgattagt cgtcatcgct atgatttatt tgaatttaat
    25021 tcttttgcat tacgacattc ctcctaggag aaaatgtgaa aatgaagcca atcttttaca
    25081 ggctctagtt taagaaaaat ttaaaacagg gcaagaaggt cccatctatg cttaaatggt
    25141 ttctcttttc taaataagat ggctttaaaa gagtgatcgt tttatccatc atgttgaaaa
    25201 atatcttcgt atagcttata gagtaggtac tgaaattgtt cacctgatct acttcttata
    25261 gttatttagt tttaaatagt gtttcaaaca ttcttacact gacgagaagt ttttgagtct
    25321 tttcttgtaa cacatatagt atactgaggt tagaatagta gactgtgact tctaacaaat
    25381 tgctagaaat gaatttcaat ctcccaattt atttgcttat atattatttt aatatattaa
    25441 ataaattctg gatcataatc atttaaaaaa attttatttt tttatttttc attacgaata
    25501 atatagatga aggggaaaga gtatgaaaac agaactgttt cttttgctat tagttcaaaa
    25561 ggagaaaaaa tgaaagtaga aaatatttcg tatagggtgg atcatcgtat attgtttgat
    25621 aatatttctt ttgatacttc gagttcagac gtgacattaa ttactggtaa aaatggtaca
    25681 ggaaagtcaa ctttactata gtggattgaa actagaatag tacacatcta cttctaaaat
    25741 attgttagaa atcgatttga ctatcctgat ctatttgtcc tgttcttatt tcatttcact
    25801 atatctcaaa ttgagtatga cgaagtgcgc tcccatgtcc tgggaacgca ctttcttcat
    25861 atttttcata ttcttgaatc catcgataaa gactattggg atgaattttt aaagttgaac
    25921 taatcatttt tacaggatga ggtttacagc agagagtttg aaggctttat caaaggtttt
    25981 tcttggcata atgacttttc ctcgtttcca cttaattttg tgtctacttt attataccaa
    26041 gtccaccctt aagttagata ataaatctaa cttaaggaag ctagaaggat gagaatccag
    26101 gtggtcaaga gtcccaaact taagctgatt gggacaccca gaataatttg ctttttgaag
    26161 gcaaggccac gttcctctat attgggaagt gagagttgaa tgagagaacc agctgatgaa
    26221 aagggtgaga tattagtaga tagagcgcca ataacggtgg ctgttgtgag taagtgaata
    26281 tcaatctggg gattttgagc actgatgata gcaatgatgg gaaagagggc tggagctaca
    26341 acggataggg tggaactaaa gagtgacatc accccggcta tcacacaaaa gaacagaggt
    26401 aaccagaaat gaggaatgga tgttgtcatg aggtgcccta tcagtgtgac taaacctgac
    26461 ttgaccgcta gagacattag taagctcatg ccgcagagca tgataattgt agcccaggga
    26521 actttagcca aaatggcttc ttgcttccct aatttgagcc ttaaggcgag gcagaccatg
    26581 agtattgaga caaagccaat atcaaatgtt tttcgataag tagctatcca ggcgatgttt
    26641 gggaaaatga gatgcaacaa gggaaaaagc caaaccaaaa ccatgctgct gatcatgagc
    26701 aaggtggttt gtctttgaac cttgctgagg agtggtggtt ggtcaatagt caaggatgag
    26761 tttgttcttc ccttactata gtgactgtaa caggataata aaagcaagac aatgagtggg
    26821 tagataatgc tgacgataaa gatatgattg ccaagtgaaa aagcttgctc ttcccatccc
    26881 atttgcttaa acaggccttg aaagacaatg cctgagctac tggttatcaa attagcccct
    26941 cctgaagctc cccaattgac ggcttgagct ccaatcaaag ggtgtttgtc cgctttttga
    27001 cagagagtaa tcgctagagg acagcaaacg gccatagtag tgaaaaatcc agcacctaaa
    27061 gcagacaaaa gggttgccat caggtataaa atcatgtaga gggcgttagg gtaggtgcgt
    27121 gtgcggtaga gaatgtgttg agccaaaaca tcaagagtac cgttagttat tgcaaagtta
    27181 taaaagagag agacgctaaa aatggtaaaa aagagtgagg ttggccaaaa atgaagaagt
    27241 tctttggggc ttaatcccat gagagtggtt gcgatgaggt aagaaaaagc aatagccagc
    27301 aggccaatat tgattttggt gcggtaacca attccaatgg ctagagcaat ggcgctaatc
    27361 attattaaat gaatcattga attgtccttt cagttagaat atggaaatag gttggcaatt
    27421 ttggcgctca aaagaccacc tgtttcctat tggtacttga ctattataca caaaaaaaat
    27481 acaattgtct tgacaattgt attgacactt gttagaatta aaaatgaggt attcaggctt
    27541 gtgatttcct atggaagtta atagtgattg cctctaatgc ttacaagtga tattaaaaat
    27601 agaggaccta gtgatgtcaa tcatttcaac tgatttaacc ccttttcaaa tagatgatac
    27661 attgaaagca gccttgcgag aagatgttca ttccgaagat tacagtacca atgccatttt
    27721 tgatcatcat ggccaagcca aggtgtcgct ttttgccaag gaagctggtg ttttagcggg
    27781 gctaaccgtt tttcaaaggg tttttaccct atttgatgcc gaggtgacct tccagaatcc
    27841 tcatcaattt aaggatgggg atcgtttgac tagtggcgat ttggttttag aaatcatagg
    27901 ctcggtgaga agtctcttaa catgtgaacg cgttgccttg aattttttac aacatttatc
    27961 agggattgct tcgatgacag ctgcttatgt agaagcctta ggcgatgatt gcattaaggt
    28021 atttgatact cgaaaaacta ctcctaattt acgtcttttt gagaaatatg cagtgagagt
    28081 tggcggtggc tataatcatc gctttaattt atcagatgct atcctgctaa aagacaatca
    28141 cattgcggca gtaggtagtg ttcaaaaggc aattgctcaa gcgcgtgcct atgccccttt
    28201 tgtgaaaatg gtcgaggtgg aagtggaaag ccttgctgct gccgaagaag ctgcggcggc
    28261 gggtgctgat attatcatgt tggataatat gtcattggaa cagattgaac aggccattac
    28321 cctaattgca ggacgttctc ggattgaatg ttctggaaat attgatatga ccactattag
    28381 ccgttttcgt ggtttagcga ttgattacgt ctccagtggt agtttaaccc atagtgctaa
    28441 gagtcttgat ttttccatga aggggttaac ctaccttgat gtctaagttg taaaataaac
    28501 taacttttta aaggatgtct ttcctctaga acgagtttta tgtcagatag tttaaacgcc
    28561 tctt
//
LOCUS       DAVAZV010000025        27275 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVAZV010000025 DAVAZV010000000
VERSION     DAVAZV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27275
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.025"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            228..1910
                     /locus_tag="VQT46_001059"
     CDS             228..1910
                     /locus_tag="VQT46_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371100.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQTAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELVKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHRKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            1895..2725
                     /locus_tag="VQT46_001060"
     CDS             1895..2725
                     /locus_tag="VQT46_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2371101.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVASLLLSLQNQGRFYNPWK
                     "
     gene            2918..3421
                     /locus_tag="VQT46_001061"
     CDS             2918..3421
                     /locus_tag="VQT46_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET2371102.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      3475..3709
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            3874..4437
                     /locus_tag="VQT46_001062"
     CDS             3874..4437
                     /locus_tag="VQT46_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET2371103.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTVAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYILLKPTLKHYER"
     gene            4451..5077
                     /locus_tag="VQT46_001063"
     CDS             4451..5077
                     /locus_tag="VQT46_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2371104.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVIIAFVFYRKRWKIESFFMLGNLTLAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDQVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGALFIEFPFYDKLRFQWRFKGKQK"
     gene            5189..6061
                     /locus_tag="VQT46_001064"
     CDS             5189..6061
                     /locus_tag="VQT46_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000525616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371105.1"
                     /translation="MGMLLATRLKNKRKELKLSQKELAEGICEQGQISRMEQGKYSPG
                     SELLFQLSKRLKVSMDYFFEDTEVSSLENIDKFKELSKKFLDEREYESLHYIYELEKS
                     KRARLSAKDQIYLDWIDTLVQFCYLNHQTGAVAKLEKILLSLKKSDFYYLQLGNTLAN
                     FYFDMGQEDTYQELYQLLKENLQSLSVHHLEQLELMIKFRYNYCRYLWLNERTSEAIE
                     EITETIAICKRYNSSYRLADLYCLLGSISEGFAERDRILGFYQVSYQLYKHEENQRMM
                     LEIEKEMKLLESED"
     gene            6191..6328
                     /locus_tag="VQT46_001065"
     CDS             6191..6328
                     /locus_tag="VQT46_001065"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371106.1"
                     /translation="MKRSQVVKRCILIALLLLFLLNVLSGSLSVTTRGVDPRPAYGVS
                     L"
     gene            6752..7666
                     /locus_tag="VQT46_001066"
     CDS             6752..7666
                     /locus_tag="VQT46_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HET2371107.1"
                     /translation="MKLYQINDGIQIFESSNLEKIVIRNYRNGKKITIDHQPLLKKLL
                     LFLEVPKREEEILLYLPELSNKTLRSVLTNFMSLNIIHCQDTLIIHKKINILIIGLGT
                     TGGYLADGLCRSNINSKLFLLDKDRVDETNVGRQIYLRDDIGQYKVDVFKQKFSDKEI
                     KVFKIFINSKKDLEKICKREGIDLVIQCGDSPSPRELGKIVNTVCDTLQIPYIVNTGY
                     MSNVVPLPEFYYPNNRYNFNYKHQFSDEKLLFSQVLSKADYMVAIQSSFVMLMQIKNF
                     IFNEEPIYYGYRGYYNSVTLAWEVEKID"
     gene            7659..8672
                     /locus_tag="VQT46_001067"
     CDS             7659..8672
                     /locus_tag="VQT46_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371108.1"
                     /translation="MTKYLELDYSHSYILEGFRKNDAFIENHKECLDMLSDKIWRDNK
                     YMNTEKNISSPTRTILSRYTCNILSSLFIDISKNSIEKLIVTCENSDLNWIYNYYKSV
                     YNGVFCELRQLIQQYCKVKDKYEKWLFIKAIINQGIRQNEKEVVEFFLKQLKDNNQGI
                     FDYINSFSFYLLKFYSKDKSRIFLEEQLDIDDFLGSDKEDYARSLVFKNYASLLPDTS
                     ELKRNIMEKCLSQTPQDTDLWKEWFETYASQKEIRQKATEIFKHGYSDISLLKLVKIE
                     PDDTESLIRMIILCTSDLNSNIARYLISFLSDGRLKEFLELFVENFDFLNIIEGKTSE
                     INF"
     gene            8656..10248
                     /locus_tag="VQT46_001068"
     CDS             8656..10248
                     /locus_tag="VQT46_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001236730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371109.1"
                     /translation="MRLIFRIIRKDIILYSILTFLLSIAMVSEAFLMQFIVDSIKFGE
                     KKYVLISIFIVIFLILQTLLYYYQQFLTAVLSKKSAYEYRKLIFKNIQQTSLRLVTGE
                     KNDSILASLTTQIDQIEYNYFYSVYWGGYLLCQLVVAIVMSLYLNPLMSVLTICLSLP
                     NLFVALLFKNSLEQKQEELINETNSSIAVTQDLIEGITDWKIANREPNIFRVFESKTL
                     KLLEKQVKVEKFQYIVVSLNQLFSNVLYFGSWIVGGFLIIRGQLSLGSLIAFSQLLAR
                     ISYPVYASSDLLSKYISGKKIVEILSKEFIFSDESRNYPDEFNVISFEHYFTNIDEKD
                     MPFDKEFYKNKKYLLKGKSGSGKTTILKSILREYDDYSGIVKINGVDVRDIKESVLFD
                     NIAYVSQKPHLFSASLRDNLTLFSEDFTDNEIVEVLKFVELSKWANKDCLDMMLSNDD
                     IKLSGGEVKRVSLARALLMNKNILLLDEFSAGIDYETLLKIEKKLIDLDKMIIYVTHV
                     DIDRSGKQFDDVIDLDCLFISS"
     gene            10440..11343
                     /locus_tag="VQT46_001069"
                     /pseudo
     CDS             10440..11343
                     /locus_tag="VQT46_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091364.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            11361..11498
                     /locus_tag="VQT46_001070"
                     /pseudo
     CDS             11361..11498
                     /locus_tag="VQT46_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            11526..11867
                     /locus_tag="VQT46_001071"
     CDS             11526..11867
                     /locus_tag="VQT46_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371110.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLKNHI
                     LPLWIGMVSFF"
     gene            11840..12151
                     /locus_tag="VQT46_001072"
                     /pseudo
     CDS             11840..12151
                     /locus_tag="VQT46_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            12279..12866
                     /locus_tag="VQT46_001073"
     CDS             12279..12866
                     /locus_tag="VQT46_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET2371111.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            13256..14863
                     /locus_tag="VQT46_001074"
     CDS             13256..14863
                     /locus_tag="VQT46_001074"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET2371112.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(15422..17053)
                     /locus_tag="VQT46_001075"
     CDS             complement(15422..17053)
                     /locus_tag="VQT46_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET2371113.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGITITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            17346..22325
                     /locus_tag="VQT46_001076"
     CDS             17346..22325
                     /locus_tag="VQT46_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET2371114.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLRYQGHEVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAVLASLGLASLALTLRRKREDKD"
     gene            22415..23611
                     /locus_tag="VQT46_001077"
     CDS             22415..23611
                     /locus_tag="VQT46_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET2371115.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            23747..24274
                     /locus_tag="VQT46_001078"
     CDS             23747..24274
                     /locus_tag="VQT46_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET2371116.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETILYVFVRVLETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            24351..24707
                     /gene="glnR"
                     /locus_tag="VQT46_001079"
     CDS             24351..24707
                     /gene="glnR"
                     /locus_tag="VQT46_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET2371117.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            24744..26090
                     /gene="glnA"
                     /locus_tag="VQT46_001080"
     CDS             24744..26090
                     /gene="glnA"
                     /locus_tag="VQT46_001080"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET2371118.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(26186..26305)
                     /locus_tag="VQT46_001081"
     CDS             complement(26186..26305)
                     /locus_tag="VQT46_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET2371119.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            26793..27275
                     /locus_tag="VQT46_001082"
                     /pseudo
     CDS             26793..27275
                     /locus_tag="VQT46_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         8594 a         4569 c         5792 g         8320 t
ORIGIN      
        1 aaccatacct acggcaaggc gaaactgacg tggtttgaag agattttcga agagtataaa
       61 atgatgggga aggctgggca actagtcttt ttcgatgttt atagattagt taggcaagta
      121 agctaggata ggaatctttt tggtgctaag attttaagag aagagactgc aagaagggct
      181 tgatttatga taaaatagaa gtctaagaag cgaatgaaga gagtaagatg aaagaagcta
      241 taattgagtg gaaggatttc tctttccggt atgaaacaca acaagaaccg accttgcaag
      301 ggatagactt gaccatttac aagggagaga aagtcttaat tgttggacca tctggatcag
      361 gtaaatctac cttgggtcag tgtttgaatg ggattattcc caatatttac aagggtcaga
      421 catatggaga atttttgata aagggtcaaa cagcctttga tatgagcatc tatgataagt
      481 ctcatctggt tagcacagtt ttgcaggata cagatgggca gtttattggc ttgtctgtgg
      541 cagaagattt ggcgtttgct ctggaaaatg atgtgacagc cctagatgag atgaaaggtc
      601 gtgtttataa atgggctgaa aagctggacc ttcttccttt actggatcag cgtcctcagg
      661 atttgtcagg tggacaaaag cagcgagtca gtctggctgg tgtcttgatt gatgaaagtc
      721 cgattctctt gtttgatgag ccactcgcca atctagatcc caagtcaggt caggatatta
      781 tcgaattgat tgaccagatt cataaggaag aggggacgac gactcttatt atcgagcacc
      841 gtttggagga tgttctgcat cgccctgtgg atcggattgt cttgataaac gatggtcgta
      901 tcctttttaa tgggagccct gaccagttgc ttgcgactga tttattgact caaaatggaa
      961 ttcgagaacc cctttatcta accactctcc gtcaattagg tgtggactta gtcaaggaag
     1021 aacagttagc gaatctggat aacatgtcta tctcaaaagg tcaggttcag ctgcagaatg
     1081 aactggtaaa agaaactcca gaattgcagt cactctttaa attagaggac gtgtctttct
     1141 cttatgatga tagaccgatt ttaaaatccc tacatttaga tattaaaaag ggtgaaaaga
     1201 ttgctattgt cggaaaaaat ggagcaggga aatcaactct agccaaggct ataagtagct
     1261 ttattcagac ggaaggacgc tatctttggg aaaaacagga tataaaaggc gattctgttg
     1321 cagagcgggc ggaacgagta ggctatgtgc tacaaaatcc taatcaaatg atttcaacca
     1381 atatgatttt tgatgaggtg gctctagggc tccgtttgcg aggtgtggat gagaaggaaa
     1441 ttgaaacgag agtctatgaa accttgaaaa tctgtggact ttatgaattc cgtaattggc
     1501 ctatttctgc cctgtcattt ggtcagaaaa aacgtgtcac cattgcttca attttggtct
     1561 taggagctga aattattctc ctagatgaac cgactgcagg tcaagatcag aagaactata
     1621 ctgagattat ggaatttctc gaagagttac atcgaaaagg gcataccatt gtcatgatta
     1681 cccatgatat gcaattgatg ctggattatt cagaccgagt ccttgtcatg gtggatggag
     1741 aattgattgc cgatactgtt ccagccagtc tgttgagcga tcctgagctg ttagtaaaag
     1801 ccaatctaaa agaaacctcc atctttaact tggctaagaa actagatgtg gatccactgg
     1861 atttaacggc attttacaaa gaaaggagag agggatgcaa gctaaattaa tcggttacca
     1921 gcatagagat actgtgattc atcgcttgtc aggagctggg aaacttctct ttttcattct
     1981 ggtatcattg gcggccatga ttagctatga taccagaatg ctcttgctga ttgccatctt
     2041 ttcagtcttt ctcctctatt tatcagaaat tcgctttaaa gatgtttcct ttgtagccgt
     2101 ttttgcgacg gtatttgccg ttttaaacgt tttgatggtc tatctctttt ctcccgagta
     2161 tggggttgga ctttatggag agagaagtgt gatttggcag ggaatcggtg tctacactct
     2221 aaccagccag gagctctttt atctgctaaa tttggccatt aagtatcttt gcaccattcc
     2281 tctggctatt atctttttga tgacaaccca tcctagtcag tttgcttcca gtttaaatca
     2341 aattggtgtg ccctataaga ttgcttattc tgtcagcctg accttgcgct atattccaga
     2401 tttgcaggaa gaattcttta ctatcaagat gtctcaggag gcgcgtggga tggaattatc
     2461 caagaaagct tctcttatgc aacgaatcaa aggcaatctg ctcattatta cgcccttgat
     2521 ttttagctcg ctagaacgca ttgataccat tgcgactgcc atggagcttc gccgctttgg
     2581 gaaagaaaaa aaacgcacat ggtatagtta tcaggccttg aaaaaaggag actatattac
     2641 cttgctcttg gcaaccttgt ttttagtagc tagtttacta cttagcttgc agaatcaggg
     2701 acgattttac aacccttgga aatagcttga aaaaattgaa aaaatcaagt cgtttctatt
     2761 gacaatgatt ctgaaagtgt tatactaaga aagtagtttc gctgatttac ttcaaacctg
     2821 ttgtgaggta agttaacgat gccttaacca cgctgtttgc tgagcttgac tccgggcagt
     2881 gtggctattt ttttgcaatg gtgaaaggaa gcaagtcatg acaaatcaca ttgtattatt
     2941 tgaacctcaa attccacaaa atacgggcaa tatcgcgcgt acttgcgctg cgaccaattc
     3001 tcccctccac atcatcaagc ctatgggctt tcctattgat gaccgcaaga tgaagcgggc
     3061 tggattggat tactgggata agctagagat ttatttttac gagagtttgg aagatttcat
     3121 atctcagatg aagggaaaac tctatctgat ttcgaaattc gcggaaaaag tctattctga
     3181 ggtggattta tcgactgacg aggaccatta ttttctcttt ggacgtgaag acaagggctt
     3241 acctgaagat tttatgcgag aacatcctga gaaggctctc cgtattccca tgaatgatga
     3301 acatgtccgc agtctcaatg tgtctaatac cgtctgcatg attgtctatg aggctcttcg
     3361 ccagcagaac tttgcaggtc ttgaactcgt ccatacctat gaagtggata aattgaaata
     3421 aaaaatgaaa atgaacaaaa tgcttgcgct tgcaagcgtt ttttgttatg ataaaagagt
     3481 cttcagggca gggtgtgatt cccgaccggc ggtgacttta actaggaaat gatcttttcc
     3541 ttttatactt tgttgacaag ctttgcctaa ccagaagtta tgcctacagc ttgtcgccta
     3601 gtctaaaaga aaaatctcta tttccttctc tttaaagaag tccgcgagcg caagctgatg
     3661 tggtgagatt ccacaaccga cagtatagtc tggatgggag aagacgaaag aatagctttg
     3721 tctgttttga tagatttata gccggattgt aaccacttgc tttgtttttc tttaatagag
     3781 taggagggaa cttttgggat ataaaaagtg agaatagata gaggaatcct ttccaacttc
     3841 ttctgatttt atagaaaatt ggaggaacct gttatgacaa acacacgtcg actttcgacc
     3901 attgcaattt tatcagccat ctcatttgtg ctgatgtact ttgactttcc gcttttacca
     3961 gcggcatctt tcctcaagat cgaatttagt atcttgccag tccttgtggg tctggtggtc
     4021 atggatttgc ctgctgctct aggagtgctc ttgcttcgct cactcttgaa attgcttctt
     4081 aacagccaag gagtgaatac ttacattggt ttgccgatga atatcgtagc tttgggagtt
     4141 tttgtcatcg tatttgcttt gatttggaaa aaggaacgga caacccttcg tttcctacta
     4201 ggctctctag ctgggactat tggtttaacc gtggctatgt tagttctcaa ctatgtttat
     4261 gctgttcctt tgtacgctaa gtttgctaac tttgatattg gaaaaatttt gggactttcc
     4321 aactacctaa tgaccatggt attacctttt aacttgattg aaggtgtaat cttttccgtt
     4381 tcattctggt tgttgtacat tctcttgaaa ccaaccttaa aacattatga aagataaaca
     4441 aacattttta atgaagggca gttttgccct tttacttttc gttattcttg gctatatggt
     4501 caaattttac cctgaaatgt tggtcaattt tgaccaatcg attcagactg ccattcgagg
     4561 agacttacca gattatttga ctattctttt tcgatccctc acacgtctga ttgatattcc
     4621 agtgattatc acttgggttg tcattatagc ttttgtcttt tatcgtaagc gatggaagat
     4681 agaaagtttc ttcatgctgg gaaatctgac tttggcaggt cttttaatcg tgacctttaa
     4741 aaatatctac cagcgcccac gaccagctat cttacatctg gtggaggaga agggattttc
     4801 cttcccaagt gggcattctc tggctgtaac gctgatggta gggactttga ttgttattct
     4861 tagtcagcgg attaaagatc aggtctggag aaaaatcgta caaatcgtcc ttggcctcta
     4921 cctagtcagt gtgctggtat caagagtcta tctgggagtt cattacccat cagatgttct
     4981 tgccagtctc tgtgtgggct tgggagccct gtttatcgag tttccctttt atgataagct
     5041 ccgcttccaa tggcgattta aaggcaaaca gaaatgatgg aaaagataaa aaattgtaca
     5101 aatacaaata gaaccatatg aaatatatac ttgaaacatg ttttggagtt tgatatattt
     5161 taataaataa agcaaggagg aagaaagtgt gggtatgtta ttagcgacac gcttaaaaaa
     5221 taaaagaaag gaattaaaat tatctcaaaa agaattagct gaggggattt gtgagcaagg
     5281 gcagattagc cgtatggagc aaggtaaata ctcacctggg tcagaattac tctttcaact
     5341 atctaagcga ttgaaggtga gcatggatta tttctttgaa gatactgagg tttctagttt
     5401 agaaaatatt gataagttta aagaattatc taagaaattt ttggatgaga gggaatatga
     5461 atctctccat tacatctatg aactggaaaa atctaaacgt gctcgtctat ctgctaaaga
     5521 ccagatttat ttggattgga ttgatacatt agttcaattc tgttatttaa atcatcaaac
     5581 aggggcagtt gcgaaactgg aaaaaatact gttatctctg aaaaaatctg atttttacta
     5641 tctacaactg ggaaatacct tggctaattt ttattttgat atggggcagg aagacacata
     5701 tcaggaactc tatcaacttt taaaagagaa cctccagtca ctatctgttc atcatttgga
     5761 acagttagaa ttgatgatta aattccgata taactattgt agatatttgt ggttgaatga
     5821 acgaacatct gaagctatag aagaaattac agaaacgata gctatttgta aaagatataa
     5881 tagtagttat cgattagcag atttgtattg tttattggga agtataagcg agggctttgc
     5941 tgaaagggat aggatactag gtttttatca agtatcttac cagctttaca agcacgaaga
     6001 gaaccagaga atgatgctag aaattgagaa ggaaatgaaa ttattggaaa gtgaagatta
     6061 agcaaaaaga tttgtattct tagataactt taatacatat tataaaaaaa ataaaaaaat
     6121 atcataaaaa ttattgacaa accaaaattg atgtgttaga atatcaccaa tagttaagga
     6181 ggtttagaag atgaaaagat ctcaagttgt caaacgatgt atattaattg ctttattgct
     6241 tctatttcta cttaatgtgt taagtggttc tttatctgta acaactagag gagttgatcc
     6301 aagaccagca tatggagttt cgctttaaag ttgtgcatag ttcttctttt atagacggag
     6361 agtttttctc aatagtaagt gattcaaatt ttgatggatg attttccatt aaattaagtg
     6421 attgcgaaaa ctttttgaaa tacattctct ttggatattg aaagtttgtt ttggattttt
     6481 ttatgaagct tatcttagct gttagattgg ggttttatgg gatttgtcct caccgggaaa
     6541 aaatcttaaa tctttgaaga aagaggtttt tatcttatgg ttagagatac atcagaagaa
     6601 attgaagtta ttgacttgtc ttctatgacc gtttcctact catctgttat gctaggaaac
     6661 tcttggatga cgtggaattg atttattaag atagattatt tggtttttac caaaaatctg
     6721 tctttttaat ttttaaagga ctaatggtga tatgaaacta tatcaaataa atgatgggat
     6781 acaaattttt gaaagtagta atcttgaaaa aatagtaatt agaaattata ggaatggtaa
     6841 gaaaataact atcgatcacc aaccattatt aaaaaaatta ctactattcc ttgaagttcc
     6901 taaacgtgaa gaagaaattc tattatatct tccagaatta tcaaataaaa cattacgaag
     6961 tgttttgacg aattttatga gtttaaatat aattcattgt caagatacat taataattca
     7021 caaaaaaata aacatattga taataggttt agggactacg ggtggatatc tggcagatgg
     7081 gttatgtcgt agtaatatta attcgaagct atttctttta gataaggatc gtgtagatga
     7141 gactaatgta ggtagacaga tttatttaag agatgatatt ggtcaatata aagttgatgt
     7201 atttaaacaa aagtttagtg ataaagaaat aaaggtattc aaaattttta ttaatagtaa
     7261 gaaagatttg gaaaagattt gcaaaaggga gggtatcgat ttggttatac aatgtggtga
     7321 ctccccttca cctcgagaat taggaaaaat tgtgaataca gtatgtgata ctctccagat
     7381 accttatata gttaacactg gctacatgag taatgtagtt cctttgccag aattttatta
     7441 tccaaataat agatacaatt ttaattataa gcatcaattt tcagatgaaa agttactgtt
     7501 ctcacaagtt ttgtctaaag ctgattatat ggtggcaatt caatcatcat ttgtaatgtt
     7561 aatgcaaata aaaaatttta tatttaatga agaacctatt tattatggtt ataggggata
     7621 ctataattct gtaacattag catgggaggt ggaaaaaatt gactaaatat ttagaattgg
     7681 attattctca ttcatatatt ttggaaggtt ttagaaaaaa tgatgcgttt attgaaaatc
     7741 acaaagaatg ccttgatatg ttatcagata agatttggcg agataataaa tatatgaata
     7801 cagaaaaaaa catatcatca ccgacacgaa caatcttatc acgctatact tgtaatattt
     7861 tatcgtcttt gtttattgat attagcaaaa atagcataga aaaattgata gtgacatgtg
     7921 aaaatagcga tcttaattgg atttataatt attataaatc ggtttacaat ggagtatttt
     7981 gtgaattgcg acaacttata caacagtact gtaaggtgaa ggataagtat gaaaagtggc
     8041 tttttataaa agctattata aatcaaggta ttcgtcaaaa tgagaaagaa gttgttgaat
     8101 tctttttaaa acaattgaag gataataatc aaggtatttt tgattacatc aatagtttta
     8161 gtttttatct attaaagttt tattcaaaag acaaatctcg cattttttta gaagagcagc
     8221 tagatataga tgattttttg ggatcagata aagaagatta tgctaggtct ttagttttta
     8281 agaattatgc ttctctattg cctgatactt ctgaattaaa aagaaatatt atggaaaaat
     8341 gtttaagtca aacacctcaa gatacagatt tatggaaaga atggtttgaa acttatgcca
     8401 gtcagaaaga gattagacaa aaagcaacgg aaatatttaa gcatggttat tcagatattt
     8461 cgttactaaa attagttaaa attgagcctg atgacactga gagtttaatc agaatgatta
     8521 tcttatgtac cagtgaccta aatagtaata ttgcaaggta tttgatttca tttttgagcg
     8581 atgggcgatt aaaagaattt ttggagttat ttgttgaaaa ttttgacttt ttgaatatta
     8641 ttgagggaaa aactagtgag attaattttt agaataatta gaaaagatat tatattatat
     8701 tctatattaa catttttgct atcaatagcg atggtaagcg aagcattttt gatgcaattt
     8761 attgttgatt caattaaatt tggtgaaaag aagtatgttt tgatttctat ttttattgta
     8821 atttttttga ttcttcagac tttattgtat tactatcaac aatttcttac agctgtatta
     8881 agtaaaaaat ctgcatatga gtaccgtaaa ttaattttta aaaatattca gcagacttct
     8941 cttaggcttg ttacaggtga aaaaaatgat agtattctag cttctttgac aacgcaaatc
     9001 gatcaaatag aatataatta tttttattct gtttattggg gtggatattt gctttgccaa
     9061 ttagtggtag ctatagttat gtcgctttat ctaaatccat tgatgtctgt attaaccatt
     9121 tgcttaagtc tccctaattt atttgtagca cttcttttta aaaactcctt ggaacaaaag
     9181 caagaagagc taattaatga gacaaattcc tcaatagcag ttactcaaga tttaattgag
     9241 ggaattactg attggaaaat tgcaaataga gaacctaata tatttagagt gtttgaaagc
     9301 aaaacattga agcttttaga gaagcaagtg aaggtagaaa aatttcaata cattgttgtt
     9361 agtttaaatc aattgttttc aaatgtttta tattttggta gttggatagt aggtggattc
     9421 ttgattatac gggggcaact ttcattaggg agtttgatag cgttctctca attattagca
     9481 agaatttctt accctgttta cgcttcttcg gatttattgt caaaatatat tagcggtaaa
     9541 aaaattgtag aaattctttc taaagaattt atattttcag acgaaagcag aaattatcca
     9601 gatgagttta atgttatttc atttgaacat tattttacaa acattgacga aaaggatatg
     9661 ccttttgata aagaatttta caaaaataaa aaatatttgt tgaaagggaa aagtggtagt
     9721 gggaaaacaa caattttaaa atcgatttta cgagagtatg atgattatag tggaattgta
     9781 aaaattaatg gggtagatgt tagggatata aaagagagtg ttctttttga caatatagct
     9841 tatgtttccc aaaaacctca cttgttcagc gcaagtctta gagacaacct gacattattt
     9901 tctgaagact tcactgataa tgagatagtt gaggttttaa aatttgttga attatctaaa
     9961 tgggctaata aagattgctt ggatatgatg ctttcaaatg atgatataaa attatcagga
    10021 ggggaggtca aaagggtttc tttagctcga gccttattga tgaataagaa tattctgtta
    10081 ttggatgagt tctctgctgg gattgattat gaaacattgt taaaaataga gaagaaactc
    10141 attgatttgg ataagatgat tatttacgtg acgcatgtgg atatagatag atccggcaaa
    10201 cagtttgatg atgtcattga tttggattgt ctttttatat cctcgtgaca tgagagttga
    10261 gtcagttgaa ttattttgtc actctgttta gttcttgttg gtagtgtcag gtaatctttg
    10321 ttaatttttc aggaagtcta ttgaaatatc ctcttggtta tatattacga ggagtaatta
    10381 atggatattc tcgagaattc aatacaacaa tttgattcta aagttaagta tgtttcttta
    10441 tttgcggaat caatctttta tcagatacca tgagctattt tgcaggtgct atgatttctc
    10501 ctttgtatgt gaggattatc ggagatgata tgacagatgc tatgggggtt agacaggcaa
    10561 ctgctggtgt agttaatatt ctcagcaacc ttataggggg agttttgatt gggggtcatc
    10621 agtcttcaga tgtttgtagg tttgaatgct ttgacctttc tttttgcact gttgggtgtg
    10681 gtgtttattc gtacttcttt gagagatatt gaggaacaga tggaggttag taaaagatta
    10741 gccgcaaaat cttttggaga gcatttcctc cattcaatga agatattgtc aagttttcca
    10801 gccatcatca aattaatatt cattgcagct atgaaccaag tgattttaag cattattatc
    10861 cctttaacga ctttgatgtt aatccatcat ccatttatct tctttgacac tgggaaatcc
    10921 attgcagcat tgtcagtggt tattttttca ggaacgattg tgggaagttt tttgagtgga
    10981 ggtatcctaa aaaatattcc cataaaaatg attgtctact ttgaagaaat tatgcatctc
    11041 tgtattctct tttcttggtt gaccaatcat ttcctccttt tattggtagt tgtcttctta
    11101 tgcgcagttg cagtaggaat gatggggcct cggattttca accttgtatt ctcgatggtt
    11161 ccagaagaag tcatgggaac catccagtca gtgcttggag tattcaatgt tgttgtacca
    11221 ggaattctta gcatgctcat cgttgcctta gcgagtgcta caaacctaaa aatcacagtg
    11281 cttccacttt ttatttttgt attgactgcc ttagcaattg tgaaagcaat gaaaatagag
    11341 taatagtagt atgaactact gtctcttttt gggtgggagt tcattaccca tcagacgtcc
    11401 ttgccagtct ctgtgtgggc ttgggagttt tgtttatcga gtttcccttc tatgacaagc
    11461 tccgcttcca atggcgattt aaaggcaaac agaagtgagt atcgaattcc cttgaggaga
    11521 aagaaatgaa agtcaatata gcagatcttc atccgactca actatattta tcagaaaaga
    11581 agttgcaaga tattcagatg ctttaccagt cggcagaaac aatccaagtc gatccaatca
    11641 gtattcttgc ctttggagat tgtttgctga ttacagatgg gcatcacagg gcttatcagg
    11701 ctttattggc aggtcgggat acgatttctg ctgagtggga tagagatggt ggtgatgaac
    11761 tatatcatct ctatgcgcaa gcttgcgagg aaagaaagat ttactctgtt tttgatttaa
    11821 aaaatcatat cttacctctt tggatcggca tggtgagctt tttttgattg aagtcaagga
    11881 gaagggagaa tggtttccaa ttggggatat tacactatct caggataatc tccccattgt
    11941 gattgggaat tccgcttacc aacatcgagg acttggaaaa aagattctaa gtgctttgat
    12001 tgaattggct cgagtaaaag gatggaaaga attgagagtc aaggaaatct acacctacaa
    12061 tcatgcttct aggaggtgtt tcaagtcgct tggatttgtg gaaaatggag caacagaaaa
    12121 aggaaggagt tttatattgg aattagtcta atcctgccac tttctccccc ttaacctttg
    12181 actattccgc aaaattatcg taaaataaag agtaaatgat aaaatgaggt cagagtctgt
    12241 tcgctctgac gatagtagta taaatgagga gaaacgcttt ggaattagaa gtatttgctg
    12301 ggcaagaaaa aagtgaacta tctatgattg aggtagcgcg tgctatatta gaacttcgtg
    12361 gtcgcgatca tgagatgcat tttagcgatc ttgtaaacga aattcaaaac taccttggaa
    12421 catcaaacag cgatatccgc gaagctttgc ctctgttcta cacagagttg aactttgacg
    12481 gtagcttcat ctcacttggg gacaacaaat ggggtcttcg ttcatggtat ggtgtggacg
    12541 aaatcgacga agaaatcatc gctcttgaag aaaatgacga cgatgaagta gcaccaaaag
    12601 ctaagaaaaa acgtgtcaat gcctttatgg atggtgattc agatgccatt gactacaatg
    12661 cagatgatcc agaagacgaa gatgcatacg aagcagatcc agctctttca tacgatgatg
    12721 aaaatccaga tgatgaaaaa aatgaagtgg aagcttatga tgcagaaatc aacgaaatcg
    12781 ctccagatga cttgggagaa gatgtggatc tcaacgaaga cgacgacgag ttttcagatg
    12841 acgacgctga aaccagcgag gaataagagt tagctattga caattatcct atttttaggt
    12901 atcatattgt ttgggcacct cttttagagg tcggggctcc ctagttctta gggagctatt
    12961 tttgtttttt caagaagtta tcttcttgta ttttatactc aatgaaaatc aaagagcaag
    13021 ctaggaaact ggccgtaggc tgctcaaaac actgttttga ggttgtagat aagactgaca
    13081 aagtcaggaa cacatatcta cggcaaggcg acgttgacgc ggtttgaaga gattttcgaa
    13141 gagtattagt tgtgaatctg gtgcagtcgt cccagattat tcttattagt agggtcttgt
    13201 tttctatatc ccctcgtagt taacaagacc ttgagcattt tagaaagagg aatctatgtc
    13261 tacgaaatat atttttgtaa ctggtggtgt ggtatcgtct attgggaaag ggattgtggc
    13321 agcgagtcta ggccgtctct tgaaaaatcg tggtctcaaa gtaaccattc aaaagtttga
    13381 cccttatatc aatattgatc cgggaaccat gagtccttac cagcacgggg aagtttttgt
    13441 gacagatgac ggagctgaga cagatttgga cttgggtcac tatgaacgtt tcatcgatat
    13501 caatctcaac aaatattcca acgtgacaac tgggaaaatt tacagtgaag ttcttcgtaa
    13561 agaacgccgt ggagaatacc ttggggcaac tgttcaagtc attcctcata tcacagatgc
    13621 tttgaaagaa aaaatcaagc gtgccgctct aacgaccgac tctgatgtca ttatcacaga
    13681 ggttggtgga acagtaggag atatcgagtc cttgccattc ctagaggctc ttcgtcagat
    13741 gaaggcagat gtgggtgcgg ataatgtcat gtatatccat acaaccttgc ttccttacct
    13801 caaggctgct ggtgaaatga aaaccaaacc aacccaacac tctgtcaaag aattgcgtgg
    13861 cttgggaatc caaccaaata tgttggttat tcgtacagaa gagccagctg gtcaaggaat
    13921 taaaaataaa ctggcccagt tctgtgatgt ggcaccagaa gccgttatcg aatcgttgga
    13981 tgttgaacac ctttaccaaa ttccactgaa cttgcaggca caagggatgg accaaattgt
    14041 ttgtgatcat ttgaaattag acgcaccagc agcggatatg acagaatggt cagccatggt
    14101 ggacaaggtc atgaacctca agaaacaagt taagatttcc cttgttggta agtatgtgga
    14161 gttgcaagat gcctatatct cagtggtcga agccttgaaa cactctggct atgtcaatga
    14221 tgtagaagtt aaaatcaatt gggtcaatgc caatgatgtg acagcagaga atgtagcaga
    14281 actcttgtct gatgcggacg ggatcatcgt accaggtggt tttggtcaac gtggtacaga
    14341 agggaaaatc caagccatcc gctatgcgcg tgaaaatgat gttccaatgt tgggagtctg
    14401 cttgggaatg cagttgacat gtatcgagtt tgctcgtcac gttttaggtc ttgaaggtgc
    14461 caattctgca gagcttgcac cagaaacaaa ataccctatc attgatatca tgcgtgatca
    14521 gattgatatt gaggatatgg gtggaaccct tcgtttggga ctttatccgt ctaagttgaa
    14581 acgtggctct aaggctgctg ctgcttatca caatcaagaa gtggtgcaac gccgtcaccg
    14641 tcaccgttat gagtttaata atgccttccg tgagcagttt gaggcagcag gttttgtctt
    14701 ttcaggagtt tctccagaca atcgtttggt agaaatcgtg gaaattcctg aaaataaatt
    14761 ctttgtagct tgtcagtatc accctgaact gtcaagccgt ccaaaccgac cagaagaact
    14821 ctacactgcc tttgttactg cagcggttga gaacagcaat tagcaaaatc agaacctttg
    14881 agaaaaatct cagaggtttt ttgcatacga tgatattgca atatatctga ggtagggggc
    14941 ctctgtatgt acctgctacc gttgaaatca atagcgactc cctcttgccc tgtgctagtg
    15001 aatggattta tcagtatatt gaaatgaaat aaaatttgaa caaattaatt cggaaagcca
    15061 aatcaatttc tagcaaagtt ttaggaactg gattgtatag tgaattgaaa taagatgtga
    15121 acatctctat cagaaaagtc aaattaattt atagaaatat tttagcagtc aagatgtact
    15181 gttatagatt caatacatta tactttttta atttaatcca ctatagtaaa atgaaataag
    15241 aacaggacaa atcgatcagg acagtcaaat cgatttctaa caatgtttta gaaatagagg
    15301 tgtactattc tagtttcaat atactatata tctgcagaat actctttcag tttcattcag
    15361 cctagtcttg cttaggaaaa agtaaaaagc catccaatta tgatggatag cttcttggtt
    15421 cttagatttg ttctgcaaaa accttttcag caaggttcat agcgtggtct gatacacgag
    15481 tgtagtgtga gatgatgtcg ataaagttga ccccagcttg tgttgaacat tcgcctttgt
    15541 tgaggcgttt gatgtgggtt tttctgagaa cacgttctat cttattgatt gcttcatgac
    15601 gttctacaag actgcgtgct ttttcaatat cattgttttc cacactatcc agagcatctt
    15661 tgataaagtc actagtttgg cggtaaactt cctctaattc tttcaaggcg gcatcagaaa
    15721 attcaacatt tttccgttga agatagtcag tcagattgag tagagcctcc gtgtggtctc
    15781 caatccgttc caaatcacgg gaggaatcaa ggatattggt aagcacttca ctttcttttt
    15841 ggctgagagc ttcgcttgaa agggcaatga gataacgtgt taattgctca tcgatggtgt
    15901 taattgcttc ttcggtttta tgcccttttt cagcaacttt ttcatccaag tcaatgatgt
    15961 acttatagga aaggtcaaag gctttagcag cgtagtttcc taagtgcaag agctctttct
    16021 tagcatttcc tagagcgata gatggggcct gtttgatgaa atgttcatca agatataagg
    16081 gttcgtattt gacaacctcg tcctctccag gaataatctt ggttacaaag taagccagag
    16141 ctccgataaa tggaaattgg acaatggtgt tggtaatatt aaaggttccg tgagcaaagg
    16201 cgatggtcat ttccggtgct agatttagcg tagcttcaaa ccaatgaatc aggacagtaa
    16261 aaggaactag aaaaataacg cagacgactg ttccgataac gttgaaggca acatgagctc
    16321 ctgctacccg tttagctgca atattagccc ctaaagaggc aatgatggct gtaatggtta
    16381 tcccgatatt gtcaccaaat agaactggca aagctccctg taggtcaatt agattgccgg
    16441 cgtagaggtt ttgtaaaatc ccaatggtag ccgaagaagc ttgaattagc aaggtcaagc
    16501 cggtaccgac aaagacaccc aaaacaggat tcttacttag ctcaatcata tagtccttaa
    16561 agacctgtaa atccttgagt ggagccattg cgccgctcat gagattgagg gcaaaaaaga
    16621 taccaccgac accaaagagg atgcgtccga tattattgac tgtccgattt tttgtaaaaa
    16681 agagacagac ggcaccgata aagagcatag gtagggcata gttacctaat ttaaaaccga
    16741 tgagaaagga tgtgacagtt gtcccaatat tagcacccat gacaatcccg atagcctgac
    16801 gtaaggttaa gagaccggca ctgaccaggc cgactgtgat aactgttaca ccagaactag
    16861 actgaattag agcagtcatc ccaataccaa ccagaactcc aaagaaagga ttactagtat
    16921 atttgtcaat gtaaaaacga aggcgatctc cagcagcttg ttgcaaaccg tctcccatgg
    16981 tcttgatgct atataagaat agccccagac cacctaaaaa gtgaaataaa atttcctgcc
    17041 aattaatgga catttctttt tcctccgaaa aataatcgcg gaatatcttc tattctattt
    17101 taaaggataa aagtaaatct aacaagtgtt aatgtcaagt ttgtaaaaga aaattataat
    17161 tgataagtgt attattttta agagttttta accttatttt agatttgtgc aaacagttat
    17221 tgttttttgt ctaaaaatgt tttaggataa aaatgtgatt atcatggttc tagagtttga
    17281 taaaaaacta cagaatataa agcgctttct tgaaaacaac aaaatcaatc ttttaggagg
    17341 agaaaatgaa gaatccattt tttgaaagac gttgtcgtta cagtattcgt aagttatcag
    17401 taggagcctg ctcgctgatg attggtgctg ttttatttgc tggtccagcc ttggctgaag
    17461 aaactgcagt tcctgaaaat agcggagcta atacagagct tgtttcagga gagagtgagc
    17521 attcgaccaa tgaagctgat aagcagaatg aaggggaaca tgctagagaa aacaagctag
    17581 aaaaggcaga aggagtagcg atagcatctg aaactgcttc gccagcaagc aatgaagctg
    17641 caactactga aactgcagaa gcagctagcg cagctaaacc agaggaaaaa gcaagtgagg
    17701 tggttgcaga aacaccatct gcagaagcaa aacctaagtc tgacaaggaa acagaagcaa
    17761 agcccgaagc aactaaccaa ggggatgagt ctaaaccagc agcagaagct aataagactg
    17821 aaaaagaagt ccagccagat gtccctaaaa atacagaaaa aacattaaaa ccaaaggaaa
    17881 tcaaatttaa ttcatgggaa gaattgttaa aatgggaacc aggtgctcgt gaagatgatg
    17941 ctattaaccg cggatctgtt gtcctcgctt cacgtcggac aggtcattta gtcaatgaaa
    18001 aagctagcaa ggaagcaaaa gttcaagcct tatcaaacac caattctaaa gcaaaagacc
    18061 atgcttctgt tggtggagaa gagttcaagg cctatgcttt tgactattgg caatatctag
    18121 attcaatggt cttctgggaa ggtctcgtac caactcctga cgttattgat gcaggtcacc
    18181 gtaacggggt tcctgtatac ggtacactct tcttcaactg gtctaatagt attgcagatc
    18241 aagaaagatt tgctgaagct ttgaagcaag acgcagatgg tagcttccca attgcccgta
    18301 aattggtaga catggccaag tattatggct atgatggcta tttcatcaac caagaaacaa
    18361 ctggagattt ggttaaacct cttggagaaa agatgcgcca gtttatgctc tatagcaagg
    18421 aatatgctgc taaggtaaac catccaatca agtattcttg gtacgatgcc atgacctata
    18481 actatggacg ttaccatcaa gatggtttgg gagaatacaa ctaccaattc atgcaaccag
    18541 aaggagataa ggttccggca gataacttct ttgctaactt taactgggat aaggctaaaa
    18601 atgattacac tattgcaact gccaactgga ttggtcgtaa tccttatgat gtatttgcag
    18661 gtttggaatt gcaacagggt ggttcctaca agacaaaggt taagtggaat gacattttag
    18721 acgaaaatgg gaaattgcgc ctttctcttg gtttatttgc cccagatacc attacaagtt
    18781 taggaaaaac tggtgaagat tatcataaaa atgaagatat cttctttaca ggttatcaag
    18841 gagaccctac tggccaaaaa ccaggtgaca aagattggta tggtattgct aacctagttg
    18901 cggaccgtac gccagcggta ggtaatactt ttactacttc ttttaataca ggtcatggta
    18961 aaaaatggtt cgtagatggt aaggtttcta aggattctga gtggaattat cgttcagtat
    19021 caggtgttct tccaacatgg cgctggtggc agacttcaac aggggaaaaa cttcgtgcag
    19081 aatatgattt tacagatgcc tataatggcg gaaattccct taaattctct ggtgatgtag
    19141 ccggtaagac agatcaggat gtgagacttt attctactaa gttagaagta actgagaaga
    19201 ccaaacttcg tgttgcccac aagggaggaa aaggttctaa agtttatatg gcattctcta
    19261 caactccaga ctacaaattc gatgatgcag atgcatggaa agagctaacc ctttctgaca
    19321 actggacaaa tgaagaattt gatctcagct cactagcagg taaaaccatc tatgcagtca
    19381 aactattttt cgagcatgaa ggtgctgtaa aagattatca gttcaacctc ggacaattaa
    19441 ctatctcgga caatcaccaa gagccacaat cgccgacaag cttttctgta gtgaaacaat
    19501 ctcttaaaaa tgcccaagaa gcggaagcag ttgtgcaatt taaaggcaac aaggatgcag
    19561 atttctatga agtttatgaa aaagatggag acagctggaa attactaact ggctcatctt
    19621 ctacaactat ttatctacca aaagttagcc gctcagcaag tgctcagggt acaactcaag
    19681 aactgaaggt tgtagcagtc ggtaaaaatg gagttcgttc agaagctgca accacaacct
    19741 ttgattgggg tatgactgta aaagatacca gcctaccaaa accactagct gaaaatatcg
    19801 ttccaggtgc aacagttatt gatagtactt tccctaagac tgaaggtgga gaaggtattg
    19861 aaggtatgtt gaacggtacc attactagct tgtcagataa atggtcttca gctcagttga
    19921 gtggtagtgt ggatattcgt ttgaccaagc cacgtaccgt tgttagatgg gtcatggatc
    19981 atgcaggagc tggtggtgag tctgttaacg atggcttgat gaacactaaa gactttgacc
    20041 tttattataa agatgcagat ggtgagtgga agctagctaa ggaagtccgt ggtaacaaag
    20101 cacacgtgac agatatcact cttgataaac caatcactgc tcaagactgg cgcttgaatg
    20161 ttgtcacttc tgacaatgga actccatgga aggctattcg tatctataac tggaaaatgt
    20221 atgaaaagct tgatactgag agtgtcaata ttccgatggc caaggctgca gcccgttctc
    20281 taggcaataa caaggtacaa gttggctttg cagatgtacc ggctggagca actattaccg
    20341 tttatgataa tccaaattct caaactccgc tcgcaacctt gaagagcgaa gttggaggag
    20401 acctagcaag tgcaccattg gatttgacaa atcaatctgg tcttctttat tatcgtaccc
    20461 agttgccagg caaggaaatt agtaatgtcc tagcagtttc cgttccaaaa gatgacagaa
    20521 gaatcaagtc agtcagccta gaaacaggac ctaagaaaac aagctacgcc gaaggggagg
    20581 atttggacct tagaggtggt gttcttcgag ttcagtatga aggaggaact gaggacgaac
    20641 tcattcgcct aactcacgca ggtgtatcag tatcaggttt tgatacgcat cataagggag
    20701 aacagaatct tactctccaa tatttgggac aaccagtaaa tgctaatttg tcagtgactg
    20761 tcactggcca agatgaagca agtccgaaaa ctattttggg aattgaagta agtcaggaac
    20821 cgaaaaaaga ttacctagtt ggtgatagct tagacttgtc tgaaggacgc tttgcagtgg
    20881 cttatagcaa tgacaccatg gaagaacatt cctttactga tgagggagtt gaaatttctg
    20941 gttacgatgc tcaaaagact ggtcgtcaaa ccttgacgct tcgttaccaa ggtcatgaag
    21001 tcaactttga tgttttggta tctccaaaag cagcattgaa cgatgagtac ctcaaacaaa
    21061 aattagcaga ggttgaagct gctaagaaca aggtggtcta taactttgct tcaccagaag
    21121 taaaagaagc tttcttgaaa gcaattgaag cggccgaaca agtgttgaaa gaccatgaaa
    21181 ctagcaccca agatcaagtc aatgaccgac ttaataaatt gacagaagct cataaagctc
    21241 tgaatggtca agagaaattt aaggaagaaa agacagagct tgatcgttta acaggtgagg
    21301 ttcaagaact cttggctgcc aaaccaaacc atccttcagg ttctgcccta gctccgcttc
    21361 ttgagaaaaa caaggccttg gttgaaaaag tagatttgag tccagaagag cttgcaacag
    21421 cgaaacagag tctaaaagat ctggttgctt tattgaaaga agacaagcca gcagtctttt
    21481 ctgatagtaa aacaggtgtt gaagtacact tctcaaataa agagaagact gtcatcaagg
    21541 gtttgaaagt agagcgtgtt caagcaagtg ctgaagagaa gaaatacttt gctggagaag
    21601 atgctcatgt ctttgaaata gaaggtttgg atgaaaaagg tcaagatgtt gatctctctt
    21661 acgcttctat tgtgaaaatc ccaattgaaa aagataagaa agttaagaaa gtatttttct
    21721 tacctgaagg caaagaggca gtagaattgg cttttgaaca aacggatagt catgttatct
    21781 ttacagcacc acactttact cattatgcct ttgtttatga atctgctgaa aaaccacaac
    21841 ctgctaaacc agcaccacaa aacaaagtcc ttccaaaacc tacttatcaa ccggcttctg
    21901 atcaacaaaa ggctcctaaa ttggaagttc aagaggaaaa ggttgccttt catcgtcaag
    21961 agcatgaaaa tgctgagatg ctagttgggg aacaacgagt catcatacag ggacgagatg
    22021 gactgttaag acatgtcttt gaagttgatg aaaacggtca gcgtcgtctt cgttcaacag
    22081 aagtcatcca agaagcgatt ccagaaattg ttgaaattgg aacaaaagta aaaacagtac
    22141 cagcagtagt agctacacag gaaaaaccag ctcaaaatac agcagttaaa tcagaagaag
    22201 caagcaaaca attgccaaat acaggaacag ctgatgctaa tgaagcccta atagcagtct
    22261 tagccagcct tggtcttgct agtttagcct tgaccttgag acggaaaaga gaagataaag
    22321 attaaatatc gaaaaatctt gtgaaatctt tccttatatt tccaaagtgt gatataatag
    22381 tttcgaataa aataaataaa ggagtttttg taacatggca aaacttactg ttaaagacgt
    22441 tgacttgaaa ggtaaaaaag tcctcgttcg tgttgacttc aacgtaccat tgaaagatgg
    22501 cgtaatcact aacgataacc gtatcacagc agctcttcca actattaagt acatcatcga
    22561 acaaggtgga cgtgcaattc ttttctctca ccttggacgt gtgaaagaag aagctgataa
    22621 agctggcaaa tcacttgctc ctgtagcagc tgacttggca gcaaaacttg gtcaagatgt
    22681 tgttttccca ggtgtcactc gtggtgctga attggaagcg gcaatcaacg ctcttgaaga
    22741 tggacaagtt ctcttggttg aaaacactcg ttacgaagat gttgacggca agaaagaatc
    22801 taaaaacgat cctgaacttg gtaaatactg ggcatcactt ggagatggta tcttcgtaaa
    22861 cgatgcattc ggtacagctc accgtgcaca cgcatctaac gttggtatct cagcaaacgt
    22921 tgaaaaagca gttgctggtt tccttcttga aaacgaaatt gcctacatcc aagaagcagt
    22981 tgaaactcca gaacgtccat tcgtggctat ccttggtggt tcaaaagttt cagacaagat
    23041 cggtgttatc gaaaacttgc ttgaaaaagc tgataaagtc cttatcggtg gtgggatgac
    23101 ttacacattc tacaaagcac aaggtatcga aatcggtaac tcacttgtag aagaagacaa
    23161 attggatgtt gcgaaagctc ttcttgaaaa agcaaatggt aaattgatct tgccagttga
    23221 ctcaaaagaa gctaacgcat ttgctggtta cactgaagtg cgtgacactg aaggtgaagc
    23281 agtttctgaa ggcttccttg gtcttgacat cggtccaaaa tctatcgcca aatttgacga
    23341 agctttgact ggtgccaaaa cagttgtatg gaacggacct atgggtgtat ttgaaaaccc
    23401 agatttccaa gctggtacaa tcggtgtgat ggacgctatc gtgaaacaac caggagttaa
    23461 atcaatcatc ggtggtggtg actcagctgc cgcagcgatt aaccttggcc gtgcagacaa
    23521 gttctcatgg attagtacgg gtggtggagc atcaatggaa cttcttgaag gtaaggttct
    23581 tccaggactt gcagccttga cagaaaaata agattttata aacaaatcaa agaagagagg
    23641 gatgaaagtt cctcttttct tttgcttaaa ataaaaacgc ttcctctcaa ctattactca
    23701 taaaaatcac cgatttatga taaaatggaa atagaaagtt gagattatga gttattttaa
    23761 aaaatataaa ttcgataaat cccagttcaa acttggtatg cgaaccttta aaacaggtat
    23821 tgctgttttt ctagttctct tgatttttgg cttttttggc tggaaaggtc ttcaaattgg
    23881 tgctttgaca gccgttttta gcctgaggga gagttttgat gagagtgttc attttgggac
    23941 ttcgcgtatt ctaggaaata gtatcggtgg actctatgcc ttggtcttct tcttattaaa
    24001 tacttttttc cacgaagcct tttgggtgac cttggtagtt gttccaatct gcaccatgtt
    24061 aaccattatg acaaatgtag ccatgaataa caaagcaggg gttattggtg gtgtagcagc
    24121 tatgttaatc attaccctat caattccaag tggtgagaca attttgtacg tgtttgtgcg
    24181 tgtattagaa acgtttatgg gagtttttgt cgcaattatc gtaaattacg atattgatcg
    24241 tattcgtctc tttttagaga aaaaagaaaa ataatgttac attttataac attatcaatt
    24301 gacgtttgtc tttttttaga ctataataga cagaaagaag gaaattgtaa atgaaggaaa
    24361 aagaatttcg ccgaaatatg gctgtttttc ctatcggcag tgttatgaag ttgaccgatt
    24421 tatcggcgcg tcagattcgt tattatgaag atcaagagtt gatcaagccc gatcgaaacg
    24481 aaggaaatcg tcgcatgtat tccttgaatg acatggatcg tctgcttgaa atcaaagatt
    24541 atatctctga aggttataat atcgctgcca ttaagaaaaa atatgctgaa cgtgaagcga
    24601 aatccaagaa agcggttagt cagactgaag tacgtcgtgc acttcacaat gaactcctcc
    24661 aacaggggcg ttttgcttca gtacagtcac cttttggtcg cggttaggca accgcaagta
    24721 gtcatagatt aaggagaaaa cttatgccaa tcacagctgc agatattcgt cgtgaagtca
    24781 aggaaaaaaa tgttaccttt attcgtctta tgttctcaga tattttggga accatgaaaa
    24841 acgtcgaaat tcctgctaca gatgaacagt tagataaggt cttgtcgaac aaggttatgt
    24901 ttgatggatc ttctattgaa ggttttgtac gtatcaatga gtcggatatg tacttgtacc
    24961 cggacttgga tacatggaca gtcttccctt ggggagatga aaatggaagt gttgcaggtc
    25021 tgatctgtga tgtctataca acagaaggtg aaccatttgc gggtgaccct cgtggtaatt
    25081 tgaaacgagc tcttcgtcac atggaagaag ttggattcaa atccttcaac cttggtccag
    25141 agccagaatt cttcctattt aagttggatg aaaatgggga cccaacactt gaagtgaatg
    25201 acaagggtgg ctactttgat ttggcaccta ctgaccttgc ggacaacaca cgtcgtgaga
    25261 ttgtgaatgt cttgaccaaa atgggatttg aagtagaagc gagtcaccac gaggttgcgg
    25321 ttggacagca tgagattgac tttaagtacg atgaagttct ccgtgcttgt gataagattc
    25381 aaatctttaa gcttgttgtt aaaaccattg ctcgcaaaca cggactttac gcaacattta
    25441 tggcgaagcc aaaatttggt attgctggat caggtatgca ctgtaatatg tccttgtttg
    25501 atgcagaagg aaataacgcc ttctttgatc caaatgatcc aaaaggaatg cagttgtcag
    25561 aaacagctta ccatttccta ggcggtttga tcaagcatgc ttacaactat actgccatca
    25621 tgaacccaac agttaactca tacaaacgtt tggttccagg ttatgaagcg cctgtttaca
    25681 ttgcttgggc tggtcgtaac cgttcgccac ttgtgcgcgt acctgcttca cgtggtatgg
    25741 gaactcgtct tgagttgcgt tcagtggatc caatggcgaa cccttacatt gctatggctg
    25801 ttcttttgga agttggtttg tatggtattg aaaataaaat cgaagcacca gctcctatcg
    25861 aagaaaatat ctacatcatg acagcagaag agcgcaagga agctggtatt acagaccttc
    25921 catcaactct tcacaacgct ttgaaagctt tgacagaaga tgaagtggtt aaagctgctc
    25981 tcggagatca catctacact agcttccttg aagccaaacg aatcgaatgg gcaagttatg
    26041 caaccttcgt ttcacaatgg gaaattgata attatttaga cctttactaa tactaatata
    26101 gaagaaagat tgcctgtggg taaacagtca cacagcagtc taagccatca aatacctata
    26161 acccttaaaa tagcgatttc ggtcgctatt tatttttcga aaaatcctct tgactctttt
    26221 gcgaattaga tttatcatca gacgtgtaga agaaaatcaa ggagtcacta tggaaaaatt
    26281 caatttcaaa aacaatatcg ggcaagaaaa caagttactt caaatcgaaa tctacaagtt
    26341 tactaacttt tgcaagcttc aaaattacac atctgtaaat attttttcga aagatatatt
    26401 tgaagccata gtaaattgag actagaatag tacactacat ctgctaaaaa tttctagaaa
    26461 ttaatttaac tttcctaatc gatttgttta catcttattt caatctacta tattatctca
    26521 ataaatgatg atggcgactg ttttgtttgt gcttgtcgat ttttgaatcc tgatcgagcg
    26581 gaagaatatt tctgccgagg ttgtcaaggg gaaaatcctg aagatattga attttatgat
    26641 gaacaattac aggcagaaaa ggtggaggct ttgaatattc gattggaagt aaaaaattga
    26701 attatctaca atctcatcaa caataaacct atttcaaccc cattatctat aggcgtattt
    26761 ttacgccttt ttatatactt gaagcacata agaaacatta tgggaagttt gctgatggaa
    26821 gtactcaaga aattgatgtt ccttatgata ttcctgatac ttgggagtgg gtgaggataa
    26881 aatcaattta ttggaatttt gggcaaaata agccagagaa atcctttagg tatatagata
    26941 cgtctagtat tgatagaaaa aagaacataa tcaactacaa aaatctacaa tatctttcac
    27001 ctgaacaagc gccttcccgt gccagaaaat tagtttcgca gaatagtgtc ttattttcaa
    27061 cagttagacc atatctaaaa aatattgctg tagttagaga acttaaagag tatttgatag
    27121 ctagtacagc atttattgtt ttggatactt tacttaacga aacatatttg aaatattatt
    27181 tattatcaga taattttatc aatcgtgtta ataataaatc tactggaaca agttatcctg
    27241 caatcaatga ttataatttt aatctattat taatt
//
LOCUS       DAVAZV010000026        26033 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVAZV010000026 DAVAZV010000000
VERSION     DAVAZV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26033
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.026"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..140
                     /locus_tag="VQT46_001083"
     CDS             <1..140
                     /locus_tag="VQT46_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371120.1"
                     /translation="RSKVENIFAKVKTFKIFSTTYRNHRKRFGLRMNLSAGIINHELG
                     F"
     gene            complement(303..554)
                     /locus_tag="VQT46_001084"
     CDS             complement(303..554)
                     /locus_tag="VQT46_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371121.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNVEWSHADSYFLS
                     FVSDDVEERYIENVYLDSLSVKQKFKFIFDFGDEWRFEC"
     gene            complement(844..2724)
                     /locus_tag="VQT46_001085"
     CDS             complement(844..2724)
                     /locus_tag="VQT46_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET2371122.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDGLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDIL
                     CPILDQHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(2718..3587)
                     /locus_tag="VQT46_001086"
     CDS             complement(2718..3587)
                     /locus_tag="VQT46_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2371123.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPDLENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNILCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(3671..6316)
                     /locus_tag="VQT46_001087"
     CDS             complement(3671..6316)
                     /locus_tag="VQT46_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET2371124.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDERFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELIVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVHISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(6407..7687)
                     /locus_tag="VQT46_001088"
     CDS             complement(6407..7687)
                     /locus_tag="VQT46_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET2371125.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSIDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            7858..9942
                     /locus_tag="VQT46_001089"
     CDS             7858..9942
                     /locus_tag="VQT46_001089"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET2371126.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKENKWLDIHTEQNHSHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPNH"
     gene            complement(9982..11661)
                     /locus_tag="VQT46_001090"
     CDS             complement(9982..11661)
                     /locus_tag="VQT46_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET2371127.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNLDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFDCRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIYVLAFQAGETEKRLTLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            12416..13645
                     /gene="arcA"
                     /locus_tag="VQT46_001091"
     CDS             12416..13645
                     /gene="arcA"
                     /locus_tag="VQT46_001091"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET2371128.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELILSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGNLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            13703..14719
                     /gene="argF"
                     /locus_tag="VQT46_001092"
     CDS             13703..14719
                     /gene="argF"
                     /locus_tag="VQT46_001092"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET2371129.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            14884..15831
                     /gene="arcC"
                     /locus_tag="VQT46_001093"
     CDS             14884..15831
                     /gene="arcC"
                     /locus_tag="VQT46_001093"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET2371130.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVIVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            16040..17551
                     /locus_tag="VQT46_001094"
     CDS             16040..17551
                     /locus_tag="VQT46_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET2371131.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNTWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            17573..18904
                     /locus_tag="VQT46_001095"
     CDS             17573..18904
                     /locus_tag="VQT46_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET2371132.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKEAGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAEDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(19310..19600)
                     /locus_tag="VQT46_001096"
     CDS             complement(19310..19600)
                     /locus_tag="VQT46_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371133.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(19588..19839)
                     /locus_tag="VQT46_001097"
     CDS             complement(19588..19839)
                     /locus_tag="VQT46_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET2371134.1"
                     /translation="MKEFQFERKQRFSLRKYAIGACSVLLGTSLFFAGMGDQPVQDTE
                     TSSALISSHYLDEQDLSEKLKSELQWFELENKLLNLWEH"
     gene            complement(20238..21122)
                     /locus_tag="VQT46_001098"
     CDS             complement(20238..21122)
                     /locus_tag="VQT46_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET2371135.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(21267..22418)
                     /locus_tag="VQT46_001099"
     CDS             complement(21267..22418)
                     /locus_tag="VQT46_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET2371136.1"
                     /translation="MAIFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHRCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIEHENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIVEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(22564..24330)
                     /locus_tag="VQT46_001100"
     CDS             complement(22564..24330)
                     /locus_tag="VQT46_001100"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET2371137.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEANDTDIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGCAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDSGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(24387..>26033)
                     /locus_tag="VQT46_001101"
     CDS             complement(24387..>26033)
                     /locus_tag="VQT46_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET2371138.1"
                     /translation="NYRTDKTAMWALSGNFDASKSWKKEELELANWISKNYSINPVDN
                     DFRTTTLTLKGHTGHKPQINISGDKNHYTYTENWDENTHVYTITVNHNGMVEMSINTE
                     GTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVDYNGDPNRAVDGNRNGNFNSGSVTHTR
                     ADNPSWWEVDLKKMDKVGLVKIYNRTDAETQRLSNFDVILYDNNRNEVAKKHVNNLSG
                     ESVSLDFKEKGARYIKVKLLTSGVPLSLAEVEVFRESDGKQSEEDIDKITEDKVVSTN
                     KVATQSSTNYEGVAALAVDGNKDGDYGHHSVTHTKADSNAWWQVDLGEEFTVSKVDIY
                     NRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDKVVDGLLSLKVPSVGAKLVKIELKSAA
                     IPLSLAEVEAYGSKRTPKKLSNIALTKETRQSSTDYNGFSRLAVDGNKNGDYGHHSVT
                     HTKGDSPSWWEIDLAQTEELEKLIIYNRTDAEIQRLSNFDIIIYDSNNHEVFKQHIDS
                     LESNNLSIDLKGLKGKKVRISLRNAGIPLSLAEVEVYTYK"
BASE COUNT         7387 a         5814 c         5077 g         7755 t
ORIGIN      
        1 agagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaata ttttcaacaa
       61 cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgagtgct ggtattatca
      121 atcatgaact aggattctag ttttgcagga agtctattga aatactaagc ctacacagac
      181 tgatttcaat tttaccattc ttcatagtca aaaccatcat aatctggata ttgttctggc
      241 aacgttccaa ccgaacgtac gagataagct tcttcgtcct ctgtctcgat ttctctcagc
      301 acttagcatt caaaacgcca ttcatcaccg aagtcgaaaa taaacttaaa tttttgtttg
      361 acacttaggc tatccagata gacattttct atgtaacgtt cttcaacatc gtcactaaca
      421 aagctaagaa agtaagaatc tgcatgactc cactcaacat tatccatgaa aaatgcatga
      481 gcatgatcat ttgcaaaatc gaaactccat aaaatcacat ctgctagttc cgctaacgtt
      541 tttgtttttg gaatctatat atgtcggtag caaccttttt taatttgacg gaaatgatcc
      601 aagcttctac agatgctggc ttttcagctt ctatttcttg ttttactaat tttaactgta
      661 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
      721 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
      781 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
      841 gtattaagtc gtataaatcg tcgaagctgt cgcaatggta tgccactggt tagctgtagt
      901 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
      961 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     1021 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
     1081 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
     1141 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
     1201 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
     1261 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
     1321 agcgaagtgc ggtttgtcct gttcaggtgt catgtgttga tcaagaatcg gacaaagaat
     1381 atcctgataa aaaacatagc ggttgggatt gataccgctg agattgcctg gtaggtctgg
     1441 taagaggttg gcaaggtcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
     1501 gaagtgcgca gacaaaccat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
     1561 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
     1621 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
     1681 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
     1741 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
     1801 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
     1861 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
     1921 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
     1981 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
     2041 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
     2101 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
     2161 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
     2221 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgagcat aggcttcgat
     2281 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
     2341 aatctggtaa gtgtcttcca tgtaaagttc aaaggttgag tagcccatga gagccaagac
     2401 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
     2461 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
     2521 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
     2581 atagtgacct tcctcaccct ggatagagat agaggcttgg tcagactgag tgacagccac
     2641 ttccacatct ggtagagaaa tatgaccttt taaaacctca atagcttgcg tttgtttggg
     2701 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
     2761 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
     2821 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
     2881 tgactgatag agccacccag actgatgaca tctggatcga tcagatactg gatattgagc
     2941 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag gatattacca
     3001 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
     3061 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
     3121 ggggcaaggg ttgtcatgta gccaaattct ccacccaagc cgtggcgacc tcgatgaagt
     3181 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
     3241 tcaagatctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
     3301 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
     3361 accgcactga agccatcaat cacacctgtc tcttgattga ctgcacctgg aacgctcata
     3421 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
     3481 aagttttcag gcgttgaaat acttgtctta tccagtattt tcccatcagg agtcagactg
     3541 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
     3601 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
     3661 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
     3721 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
     3781 ctgatatgtg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
     3841 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
     3901 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
     3961 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
     4021 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
     4081 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
     4141 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
     4201 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
     4261 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
     4321 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
     4381 agcggatttg tggattgtca acaaagacaa tcaactcagt ttccagagga atgtttgtca
     4441 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
     4501 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
     4561 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
     4621 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
     4681 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatattgtca tccacactca
     4741 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
     4801 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
     4861 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
     4921 aattagctcc gaggtcttcg attgtagcct ctacaggacg accatccaag tcctccacac
     4981 ggtaacttgg taagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
     5041 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
     5101 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
     5161 tccactcgtt gagcaagtta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
     5221 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
     5281 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
     5341 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
     5401 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
     5461 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
     5521 gaacatattc atcaaaagaa ctatgaacaa agattacatc cgggaagagt tcatttgcca
     5581 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
     5641 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
     5701 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagttg gcaaagagaa
     5761 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
     5821 accgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
     5881 ctgccacgtg aatacctgat ttttgaagga tttgaggagc ttgtcccata tttccaaagg
     5941 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
     6001 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
     6061 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
     6121 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
     6181 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
     6241 gatggctttc aaaaggcaag taccactcac gatcccagtg actatgtgag ataatatgta
     6301 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
     6361 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cggatatcca
     6421 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
     6481 agagggtcgg atcatctacg tggaagcttt cgtgcatgac acctgtacca ccatcgcagg
     6541 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
     6601 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
     6661 cgtattctcc ttggtagaag tatggatttt cagagctcag aatggtacgg cgagtggctt
     6721 gatacacttc atcatcgatc gaacagtagc ccagataggg cgcagctagt agacttggta
     6781 catttggatc atccatgatg ctggcatttc ctaggccatc tacttcaaaa gcgtaaatct
     6841 tttcgccctt gctgttggtg gtgtaagcgt agttttcgat tccttcttgg atttcatcct
     6901 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
     6961 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
     7021 actggcaaca gtcatcactc ggacgaaaag ctgaccaagt catacctgtc actgcaaagt
     7081 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtatct cggacaaaac
     7141 gataaggaga gttcttgtgg tcttgttcaa ctgtccatag atggagaatt tccttagtcg
     7201 ctgcgacaaa agtttcatca aactgactag tctcgccagt ctctttccag aggagataag
     7261 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
     7321 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
     7381 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
     7441 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
     7501 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
     7561 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc aaagacatca acccactctg
     7621 gatggtcctt ggcccgctct gctacttcat ctagccattc tctaacaatt tctttcgaat
     7681 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
     7741 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttatct ttaaaactcc
     7801 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
     7861 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
     7921 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
     7981 accagtgacc aggatggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
     8041 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
     8101 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
     8161 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
     8221 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
     8281 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
     8341 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
     8401 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctgggga ctggcgaatt
     8461 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
     8521 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
     8581 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
     8641 tttgaccact gcctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
     8701 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
     8761 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
     8821 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
     8881 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
     8941 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
     9001 gccatgctcg aaacagccag caaagccgac cctctcggca tcaatggccg ccacggacta
     9061 gcccaatacc aagaactagg ttacctctct accgaccacc acgaaagtgt tagccatact
     9121 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
     9181 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
     9241 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
     9301 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
     9361 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
     9421 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttacga aattcacgaa
     9481 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
     9541 cacattcctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
     9601 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
     9661 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
     9721 aaaccaagct atgatctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
     9781 gaaaataaat ggctagatat tcatactgag caaaaccaca gccattttaa ctttgtcaaa
     9841 gaatgccgac tggacaaaac actcgtatca actattcaac accaagacct cctaaaagct
     9901 gaacaactaa ctttcaccct cagctggcta ccaaatcact aataaccaaa agaacctttg
     9961 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    10021 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acaaggttgg
    10081 tagcgtcagc cttttttcag tctcaccagc ttgaaacgca aggacataaa tctcgtcctg
    10141 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagcct ctaaagagga
    10201 gctactttca ctacgttcaa tcctaaaatg aagagtctct ccctttgcca cagctaggct
    10261 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataacccag gagttttata
    10321 aagggaaatc ttggtcaata cagggataga ttgtgcctcg gtaatcatca cgcgcacctt
    10381 ttgtgcctct actagcggac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    10441 aaactcctgc cagacaccat ccacctctac ttgcacatga aaagcagcga ttcgttgccc
    10501 tagcttcaaa tcttctctta actcaattac atcaaaagtt ttaggagaac ctaaatcgag
    10561 ttctaactgg atgggcaagt ctgcatcgct tgcccaagag ctggtctcaa ggccgtctgt
    10621 caaatggcga caatcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    10681 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    10741 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    10801 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    10861 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    10921 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaagatt
    10981 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    11041 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    11101 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    11161 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    11221 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    11281 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    11341 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    11401 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    11461 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    11521 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    11581 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    11641 atgcggtttg attttcttca tcgttatata tctccttctt ttgcaacttc tcttgttcac
    11701 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    11761 caactggtag gctcaggatt tttctcctca atgttccctc ttcaaacagc tctgtcatat
    11821 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    11881 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    11941 tctaagctat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    12001 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    12061 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    12121 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtc atttgtatat
    12181 tttttgaaaa attttttaaa aaaattttat atccttttta tagaagttta tgcatttgta
    12241 tctatgtatt ctatcctatg ttatgtataa taacataaaa ttgtgctaaa catcataatt
    12301 tatattattt tccgagaaat tatagccatt gacattacct aggaattgcg ttataacata
    12361 catgtaagcg gtacccaaaa tggtgccaag tcaaaatttt taaggaggaa aatacatgtc
    12421 ttctcatcca attcaggtct tctcagaaat tgggaaactg aaaaaagtta tgttgcaccg
    12481 tccaggcaag gagttagaaa acttgttgcc ggactatctt gaaaggcttc tttttgatga
    12541 tattcctttc ttggaagatg ctcaaaaaga acatgatgca tttgcccaag ctcttcgcga
    12601 tgaaggaatt gaggttctct acctagaaca actcgctgct gaatcattga cctctccaga
    12661 aatccgcgat caatttatcg aggaatactt agacgaagcc aacatccgtg atcgtcaaac
    12721 caaggttgct attcgtgaat tacttcacgg catcaaggac aaccaagaat tggttgaaaa
    12781 aacaatggct gggattcaaa aagttgaatt gccagaaatt cctgacgaag ctaaagatct
    12841 aactgactta gttgaatcag attatccatt tgcaattgac ccgatgccaa acctctattt
    12901 cactcgcgac ccatttgcaa caattggaaa cgccgtatcg cttaaccaca tgtttgcaga
    12961 tactcgtaac cgtgaaacac tctacggtaa gtatatcttc aaataccacc caatctatgg
    13021 cggaaaagtg gatttggtct acaaccgtga agaagatacg cgtatcgaag gtggagacga
    13081 gctaattctt tctaaagacg tccttgcagt aggtatctct caacgtacag acgcagcttc
    13141 tatcgaaaaa cttttggtca acatcttcaa gaaaaatgtt ggcttcaaga aagttttggc
    13201 ctttgaattt gctaacaacc gtaaattcat gcacttggat actgtcttca ctatggtaga
    13261 ctatgacaag ttcactattc acccagaaat cgaaggcaac cttcacgttt actcagttac
    13321 ttacgaaaac gaaaaactta aaattgttga agagaaaggt gacttagctg aacttcttgc
    13381 tcaaaacctt ggtgtagaaa aagttcattt gattcgttgc ggtggtggca atatcgtagc
    13441 agctgcgcgt gaacaatgga acgacggttc taacactttg accatcgcac ctggtgtggt
    13501 agttgtttat gaccgcaata ccgtgaccaa taagattttg gaagaatacg ggcttcgctt
    13561 gattaagatt cgcggaagtg aattggttcg gggccgtggt ggacctcgtt gtatgtctat
    13621 gccatttgaa cgtgaagaag tgtaatcgct gttcggtatt cgtcaataga aaatgtaaaa
    13681 aatagaaaga ggaaataata aaatgacaaa ttcagtattc caaggacgca gcttcttagc
    13741 agaaaaagac tttacccgtg cagagttaga ataccttatt ggtctttcag ctcacttgaa
    13801 agatttgaaa aaacgcaata ttcaacacca ctaccttgct ggcaagaata tcgctctcct
    13861 atttgaaaaa acatctactc gtactcgtgc agcctttaca actgcggcta tcgaccttgg
    13921 tgctcaccca gaatacctcg gagcaaatga tattcagttg ggtaaaaaag aatctactga
    13981 agatactgct aaagtattgg gacgtatgtt tgacgggatt gaattccgcg gattcagcca
    14041 acgtatggtt gaagaattgg cagaattctc aggcgttcca gtatggaacg gtctaactga
    14101 cgaatggcac ccaactcaaa tgctcgctga ctacttgact gttcaagaaa acttcggtcg
    14161 cttggaaggc ttgacattgg tatactgtgg tgatggacgt aacaacgttg ccaacagctt
    14221 gctcgtaaca ggtgctatcc ttggtgtcaa tgttcacatc ttctcaccaa aagaactctt
    14281 cccagaaaaa gaaatcgttg aattggcaga aggatttgct aaagaaagtg gcgcacatgt
    14341 tctcatcact gaagatgctg atgaagcagt taaagatgca gacgttcttt acacagacgt
    14401 ttgggtatca atgggtgaag aagacaaatt cgcagaacgt gtagctcttc ttaaacctta
    14461 ccaagtcaat atggacttag ttaaaaaagc aggcaatgaa aacttgatct tcctacactg
    14521 cttgccagca ttccacgata ctcacactgt ttatggtaaa gacgttgctg aaaaatttgg
    14581 tgtagaagaa atggaagtaa cagacgaagt cttccgcagc aagtacgctc gccacttcga
    14641 tcaagcagaa aaccgtatgc acactatcaa agctgttatg gctgctacac ttggtaacct
    14701 ttatattcct aaagtataat tttagataat aaaccgtcta ccaacagcta tgagggctgc
    14761 gactaatagc tttagtccgg tcctctttta tgtaatggta atctattatt tcttataaaa
    14821 tatgtgaaaa atcattaaat tgaaatctaa acgcattcta ttgagtgtga taaaggagaa
    14881 tttatggcaa atcgtaaaat tgtagtagct ttgggaggaa atgcgattct ttcttctgac
    14941 ccatcagcaa aggctcaaca agaagcttta gttgaaacag ctaagcatct tgtaaaattg
    15001 attaaaaatg gagatgattt gattatcact cacggtaatg gacctcaagt tgggaatctc
    15061 ttgctccaac atttggcatc agactctgaa aagaaccctg ccttcccact cgactcactt
    15121 gtcgctatga cagaaggtag catcggtttc tggttgaaaa atgctttgca aaatgctctc
    15181 ttggatgaag gcatcgaaaa aaatgttgcc tctgttgtaa cgcaagttat cgtagataaa
    15241 aatgatccag cttttgttaa cttgagtaaa ccaatcggtc ctttctattc agaagaagaa
    15301 gcaaaagcag aagccgaaaa gagcggagcg actttcaagg aagatgctgg ccgtggctgg
    15361 cgtaaggtcg ttgcctcacc aaaacctgtt gacatcaaag aaattgaaac catccgtact
    15421 cttttaaata atggtcaagt cgtcgtagct gcaggtggtg gcggtattcc cgtcgtcaaa
    15481 gaaaacaatg gacatttgac tggtgtcgaa gcggttattg ataaagactt cgcttcccaa
    15541 cgtttggcag aattggttga tgcagacctc ttcatcgttt tgacaggtgt agattatgta
    15601 tttgttaact acaacaagcc aaaccaggaa aaattggaac atgtgaatgt tgcccagctg
    15661 gaagaatata tcaaacaaga tcagtttgca ccaggtagca tgcttccaaa agtagaagca
    15721 gctatcgctt ttgtcaatgg tcgtccagaa ggaaaagcag ttattacttc ccttgaaaat
    15781 ctaggcgcct tgattgaatc tgaaagcgga acaattattg aaaaaggata agttgtttta
    15841 ctaataagat gtattctatt tctagtatct ttatatcaaa ttagaaatta ttcttgaaaa
    15901 catgtacaat atttcaaaag atactagttt tagactttaa tatggtaaaa caaatataaa
    15961 tagaaagcgt tttcttgaat gtttatttaa gaaagtagtt ggttttttac actttgttag
    16021 acatcaggag gaaaaacaaa tgagtgaaaa agctaaaaaa gggtttaaga tgccttcatc
    16081 ttacaccgta ttattgataa tcattgctat tatggccgtg ctaacttggt ttatccctgc
    16141 gggggccttt atagaaggta tttacgaggc tcagcctcaa aatccacaag ggatttggga
    16201 tgtcctcatg gcaccgattc gggctatgct aggtactcat ccagaggaag gttcgctcat
    16261 taaagaaacg agcgcagcga ttgatgtagc cttcttcatc cttatggttg gtggtttcct
    16321 tggcattgtc aacaaaactg gtgctcttga cgtagggatt gcctctatcg tgaagaagta
    16381 taagggccgc gaaaaaatgt taattttggt attgatgcct ttgtttgccc tcggtggtac
    16441 aacttatggt atgggtgaag aaacaatggc cttctatcca ctccttgtgc cagttatgat
    16501 ggccgttggt tttgatagcc tgactggtgt tgcaattatt ttgctcggtt ctcaaatcgg
    16561 ctgtttggca tctactctga atccatttgc gacaggtatt gcttcagcga ctgcgggagt
    16621 tggtacaggg gacggtatcg tacttcgtct gatcttctgg gttaccttga ctgctcttag
    16681 tacttggttt gtttaccgtt atgcggataa gattcaaaaa gatccgacta agtcactggt
    16741 ttatagtact cgcaaagaag atttgaaaca ctttaacgta gaagaatctt catctgtaga
    16801 atctacactt agcagcaaac aaaaatcagt tctcttctta tttgtgttga cattcatctt
    16861 gatggtattg agcttcattc catggacaga ccttggcgtt accatttttg atgactttaa
    16921 tacttggttg actggtcttc cagttattgg taatattgtc ggttcatcta cttctgcact
    16981 aggtacttgg tacttcccag aaggcgcaat gctctttgcc tttatgggta tcctgattgg
    17041 tgttatttat ggtcttaaag aagataagat tatctcttcc ttcatgaatg gtgctgctga
    17101 cttgctcagt gttgccttga tcgtagcgat tgctcgtggt attcaagtta tcatgaacga
    17161 cggtatgatt accgatacaa tcctcaactg gggtaaagaa ggcttgagcg gtctatcttc
    17221 acaagtcttt atcgttgtaa cttatatctt ctatctacct atgtcattct tgatcccatc
    17281 ttcatctggt cttgccagcg caactatggg tatcatggct ccacttggag aatttgtaaa
    17341 tgtccgtcct agcttgatta tcactgctta ccaatctgct tcaggtgtct tgaacttgat
    17401 tgcaccaaca tctggtattg tgatgggagc tcttgcactt ggacgtatca acattggtac
    17461 ttggtggaaa ttcatgggca aactcgtagt cgctattatt gtagtgacca tcgcccttct
    17521 tctccttgga accttccttc cattcctata aaatagtgag tgaggtgatt ccatgaaaat
    17581 agatataaca aatcaagtta aagatgaatt tcttatatca ttaaaaacct tgatttccta
    17641 tccttcagta ctcaatgaag gagaaaatgg aacacctttt ggacaagcaa tccaagatgt
    17701 cctagaaaaa actttagaga tttgtcgaga cataggtttc actacctatc ttgaccctaa
    17761 aggttattac ggatatgcag aaatcggtca gggagcagag cttctggcca ttctctgtca
    17821 tttggatgtt gttccatcag gtgatgaagc agattggcag acaccgccat ttgaagcaac
    17881 tatcaaagac ggctgggtat tcggacgtgg tgtccaagat gataaaggcc cttcgctcgc
    17941 agctctctat gcagtaaaaa gcttgctgga ccaaggtatt cagttcaaaa agcgcgtacg
    18001 ctttatcttt ggtaccgatg aggaaaccct ctggcgctgc atggcacgct acaataccat
    18061 cgaagaacag gccagtatgg gctttgcacc tgactcatct tttcctctga cctatgctga
    18121 aaaagggctt ctacaggtca aacttcatgg ccctggatcg gatcaactag agcttgaagt
    18181 aggaggcgcc tttaacgttg taccagacaa ggccaactac caaggtcccc tctatgaaca
    18241 ggtttgtaac ggtctcaaag aagctggtta tgattaccaa tccactgaac aaaccgtaac
    18301 ggttctcgga gtgccaaagc atgctaagga tgctagtcaa ggtatcaatg ctgtcatccg
    18361 actagctacc attcttgctc ctctccaaga acaccctgct ctcagttttc ttgcaacaca
    18421 agcaggtcaa gacggcacag gaagacaaat ctttggtgat atagcagatg aaccttctgg
    18481 tcacctatcc tttaatgtcg caggtctcat gatcaatcat gaacgttctg aaatccgtat
    18541 tgacattcgg actcctgtct tagctgacaa ggaagaacta gtagagttgc ttacaagatg
    18601 tgcacaaaac taccaactcc gctacgaaga gtttgactat ctagcgcctc tatacgtcgc
    18661 agaagacagt aaactcgtta gcacactgat gcaaatctac caagaaaaga ctggcgataa
    18721 cagtcctgct atttcatccg gtggtgccac ttttgctcgc accatgccaa attgtgtagc
    18781 cttcggcgcc ttattcccag gagcgaagca gacagaacat caggcaaatg aatgtgccgt
    18841 tctagaagat ttgtaccgtg ctatggatat ttatgccgaa gccgtctatc gacttgcaac
    18901 ttaatcaggc aactgtttct accaaaaaaa atcgaccgat taatgaactg caccccaaaa
    18961 gttagacaga ataaatctaa cttttggggt gttttattat gaaattgagt tatgaagata
    19021 aagttcagat ctatgaacta agaaagcaag gacaaagctt caaacagctt tcaaaaagat
    19081 ttggtgtgga tgtttctggt ctaaagtcat ctgaatcttt gagatgagct ttataaatcg
    19141 cttttttcag tttttgcact ggtgtttcga taaactcaaa ctttttagcc gtggtattgc
    19201 ctgattttat agtatattga aactagaata gtacacctct acttctaaaa catttttaga
    19261 aatcgatttg actgtcctga acgatttgtc ctgttcttat ttcattttac tatatttgag
    19321 ccacttcgtc tttaacggct ttattcataa gctcttgtaa tttttcttta ctatcaatta
    19381 cttctgattt tccgttgtaa tttattgtaa taggttttaa cttacctaat ttctcgacac
    19441 gctcattaat ttgatctttt ttgaaggctg catatgtttt tcctaagatt ttttcgaaaa
    19501 tatatttatc agatagcggt ttgccttctt cttcagcttg gtttttgtat tgatttgaaa
    19561 cataaggaac aaatccttca tagtaaccta atgctcccat aagttcaaaa gcttgttttc
    19621 taattcaaac cattgcaact cagatttcag cttttcagat aaatcctgct catccaaata
    19681 atgacttgaa attagtgctg aactcgtttc tgtatcctgt acaggctgat cacccatacc
    19741 agcaaaaaat aaactcgttc ctagcaagac cgaacaagct cctattgcat atttcctcaa
    19801 agaaaaacgc tgctttctct caaattgaaa ttctttcatc ccatctccca tcattcatta
    19861 ttactgtata ttttgtatat cagaaatagt ttgtattcac aaatctttct agttattccc
    19921 ttatcattcc taattaaggg aggtaacata caataatttt tagttaaatg tatatctatg
    19981 ttttttgttt ttcttaataa acgcaataca aaaagagcct gttgccaagc tctttgtact
    20041 caatgaaaat caaatagcaa actaggaaac tagccacagg ttgctcaaaa caccgttttg
    20101 aggtagtaga taagactgac gaagtcagct caaaacactg ttttgaggtt gcagatagaa
    20161 ctgacaaagt cagtaacatc tatacggcaa ggcgacgctg acgtggtttg aagagatttt
    20221 cgaagagtat tagtctatta tttcttctca gcgcgaaggg ctgacaagat ttgtgttcgg
    20281 atatcatcca caccatttgg cgtatttggt aaaaagatgg tttgatttcc tttagaggca
    20341 aaggtattca aggtatccaa atactggttg gtcaagagga tagacatgat ttgttcttct
    20401 gtcatgccaa cattggcttc cttgagttcg gtgatagact ctgccaatcc atccacaatc
    20461 gccttacgtt gttgggcaat ccccacacca tgaaggcggt ctttttctgc ttctgcttca
    20521 gctgcagtga caattttaat cttgtcagct tccgccaatt cttgtgctgc gacccgctta
    20581 cgttgcgccg cattgatttc attcatggat tgcttaactt ctgcatccgg ttcgactttg
    20641 gtaatcaagg ttttcacgat aatgtagccg taagtggtca tttcttctgc tacttggtgt
    20701 tgaacttcaa gggcaatctc atcttttttc tcaaacaatt catccaaggt taattttgga
    20761 acagaagagc gaagagcatc ttcgatataa gatttaatct gagattctgg acgtatgagt
    20821 ttatagtaag catctgtcac gctctgctcg ttgacacggt actgagtcgc tacattcatc
    20881 ataacgaaca cattgtcctt ggtcttagtc tcaaccacaa tatcactttg caacaagcgc
    20941 aactgaatcc gtgctgcaat cgagtcaatc ccaaaaggca agcgaatatg aataccgcta
    21001 ttagcaacct tttggtattt cccaaagcgt tcaataatcg ccaccgactg ctgacgaacc
    21061 acataaactg tactcagtgt gactatcacc aataggagca cacaaacaat cagaaaaatc
    21121 atgaaaaata ttgccataat ggaacctcca caagtatttt tctagtatta tagcacattt
    21181 aaagaaggct gtgccgtttt tactgcgatt tttcctgaaa tgtcaataat tagaggtgaa
    21241 ttgtcctatt gtcgtccaat ctcttgctaa aataactctt tataaaaggc aatcgtttct
    21301 tctaaggttg gcataaatgg atttcctggt gcgcaggcat caatcaaggc attcttagaa
    21361 aggtattcaa agtcgaaatc tttttcttca ataccaagtt cagtcagttt cttaggaata
    21421 cctactgtct cagaaagctt ctcaatctca acaatcgcat aatcggcaca ttcttgatct
    21481 gatttacctt ctacatgaag tcccaaggct ttggcaacat tgcggaaagc ttctggtaca
    21541 cgtttagcat tttcatgttc tataactggt agcaacatgg cacagcaaac accatgtggc
    21601 aaattatata ctgcaccgag ttggtgagcc attgagtgaa cataaccaag accagcatta
    21661 ttaaagctca taccaccaag gaagatggca ttgaccatac cttcacgcgc ttcaatatca
    21721 tgtccatttt ctacagcacg aggaagatat tccttgataa gctcaatagc accaatagac
    21781 agtttcttgg ttacatcata agcaccaggt gttaccaaag cttcaacagc gtgagtcaga
    21841 gcatccatac cagtagcagc agtcaaggct tgaggtttgg aaagcatgag ttcagggtca
    21901 ttgacagaaa tcaaggcaag gctattcttg tcaaccatta ccatcttaac cttgcgttct
    21961 tcatcagtaa tcacatagtt aatagtgatt tctgctgatg tacctgccgt tgtattgata
    22021 gccacaaccg gcaagccttt tttagcagac ttatgaagcc cttcataatc ctgtggtttt
    22081 ccaccatttg tagccatgat agaaatacaa ctagctgcat cctgtggaga acccccgcca
    22141 agactgatga taaaatcaca tctatgttct tgcaaagcag ctaccccatc tgtgacattt
    22201 ttacaagtag ggtttggctc tacatcgcta aagatgacat attcgattcc ttctgtatcc
    22261 agtggtttta aagtcttagg taaaatatca ctgccttcga tgtacttatc tgtcaccaaa
    22321 agtgcctttt tatagccaag ttccttgata taaggaccca cttcatttac aacacctttt
    22381 ccaataaggt tgactgccgg aacataaaat atagccatat aattttcctc ctgcgcctcc
    22441 gcgctatcta tttaacatca ttatattact ttttgtattc gttttcaatt atttgtgaat
    22501 tgtttaacaa atctttttaa aaggatagga gggacgtaag ttcacctcct atataaacaa
    22561 gttttattta tgtagtggtc ccaacaactg acatgcacga tagtctgctg attctagatc
    22621 ttctgttcca aataaggacc aatttttagg tctaaagata tcttcctcag gtacattatg
    22681 catattgaca ggaattctca acatagaagc caaggtaatc aagtctgctc caatgtgtcc
    22741 atatgttatg gctccgtgat tagctcccca attattcatg acgtcataga cagacttgaa
    22801 agcacctttt cctgtcaaac gtggagcaaa ccaagtagtt ggccatcctg aatctgtacg
    22861 attatctaaa gtatggtgaa catcttcagg aagttcaagt gtgtaacctt ctgcaatttg
    22921 tagcactgga ccaacccctt ttagaagatt gagacgtacc attgttactg gcatatcccc
    22981 cttcgtcaag aaacgagttg agaatcctcc tccacggaag tactcgcggt ttgctggtgg
    23041 gaagtctgta ttttcaagca tagcctgtac ttcactttct tccaactccc agaatggttt
    23101 cataacaggt ttgccatctc gagtagcttg acctgtacca tccaatgtac aagaaccaga
    23161 gttgattaga tgtaagaagc cagctgcagc acaaccctct aaagtatgtc ccgttacacg
    23221 tttaacagcc tctggactcc aataagtgcg cacatcagca aagatttgtg gagtatttgt
    23281 taatagataa ttaaagagca tagacacacc atttagtgaa tcattctctg tcgcaaatac
    23341 aaatggtttt cgaataccat tccagtcaaa ctgagtattg aggaaagttt ccataaaatc
    23401 tccatttgga aaatggtctg tccactgacg ttgaccttgg aaaccagcta ctaaagcatg
    23461 gtgaccaacc gcttcttcct caaaaccaag ttcagcaagc cttgggttac caaccattaa
    23521 gtcacgtcca atcatgaaca tcttaataac aaattcccat tgtttttctt tctcttcttt
    23581 agaaagaatc aaatcctcac gatttcggtc aaccccttct ttgatatgtt cttttaccca
    23641 aaccatagca cgttcgaact cttctgggtc ataaatacca cggtccatac ggcgcgtgaa
    23701 ctccgtcata tctaccgatt catttcgcat tcctaagtat tcttggaaga aatctggatt
    23761 tacaatagaa ccgccaatcc ccatcgaaac actacccatt gataggtaag cagtgtctct
    23821 catcaagcca gttgcaagag ctgcacgcgc ataacgtaaa agtttttctt tgacatcttc
    23881 tggaatatct gtatcattag cttcctgaac atctctacca taaatcccaa aggctggaat
    23941 ccctttttga gcatgtgaag ctagtacagc tgcaagatag acagctcctg ggcgttctgt
    24001 cccattaaat ccccaaatag catgaggaat atctggagac atatccatag tttcactacc
    24061 ataacaccag catggtgtaa ctgtaattgt tgcgcaaaca tttgattttt taaacaactc
    24121 atgggaagct gcagcctctg gaacacgacc aatggtagat ggagaaatca cacattccac
    24181 aggttcccca tctggatatt tcaatgtgct tgaaatcaaa tctgccacac ttttagccat
    24241 gttcattgtt tgtacttcaa gtgattcgcg tacaccttga cgacgaccat caatagtcgg
    24301 acgaatccca atacgtggat gttgaatcat actattttcc tcttattttt ctgtttcttt
    24361 catactaccg atgataattt ttaaaattac ttataagtat aaacctctac ctctgccaaa
    24421 cttaaaggaa ttcctgcgtt tctcaaagaa attctaacct tttttccctt cagccctttt
    24481 aagtctatgg atagattatt gctttctaaa ctgtcaatat gttgtttaaa aacttcatga
    24541 ttatttgaat catatataat aatatcaaaa tttgataatc tctgaatttc agcatctgtt
    24601 ctattataaa taattaactt ttctaattct tcggtttgtg ctaaatctat ctcccaccat
    24661 gaaggagaat ctcctttggt atgagtcact gaatgatgac cataatctcc gtttttattt
    24721 ccatcaactg ctagacgaga aaaaccattg taatccgttg aactctgtcg agtttctttg
    24781 gttaatgcaa tattagaaag tttcttcgga gttctctttg aaccataggc ttcaacttcc
    24841 gctaaactta acggaatagc tgctgatttt aattctattt tgactagctt agcccctaca
    24901 gaaggtactt ttaaagataa caaaccatca actactttat caaaatgtct tctaaaaact
    24961 tcttctcctg atgaagatag aaaaataaca tcaaaattag ataaacgctg aggttcggca
    25021 tctgttctat tataaatatc aactttagaa accgtaaact cttctcccag atcgacctgc
    25081 caccaagcgt tagaatctgc cttagtatga gtcaccgaat gatgtccgta atctccatct
    25141 ttattaccat caactgctaa agcagctaca ccctcataat tggttgaact ttgagtagct
    25201 accttatttg tagagactac tttatcttct gttattttat ctatatcctc ttcagattgc
    25261 ttaccatctg attctctaaa aacctctact tctgctaaac tcaaaggcac tccactcgtt
    25321 agtaatttaa ctttaatata ccttgctcct ttttctttga aatctagact aacagattca
    25381 cccgacaaat tattaacatg tttcttagca acttcgtttc tattattgtc atatagaatc
    25441 acatcaaaat tagatagacg ttgagtctca gcatctgtgc gattataaat tttaacaagc
    25501 ccaactttat ccattttttt caaatcgact tcccaccaag agggattatc tgccctagtg
    25561 tgtgttaccg aaccagagtt aaaattacca tttctgttac catccacagc tctattaggg
    25621 tctccattgt aatctacaga actttgtgtt gttggttttg catatgctat attcaaatta
    25681 ccatcattaa atttatctgg tgttgggaaa gggactgggc ctgtcccttc agtatttata
    25741 gacatctcta ccattccatt atgattaacc gtaatggtat aaacatgggt attctcatcc
    25801 caattttctg tataagtata atgattttta tcgccactta tatttatctg aggtttatga
    25861 ccagtatgcc cttttaatgt aagtgttgtt gtcctaaagt cattatctac aggattgatg
    25921 gaataatttt tgcttatcca gttcgctaac tctaattctt ctttcttcca actttttgat
    25981 gcatcaaaat ttcctgataa tgcccacata gctgtcttat ctgtcctgta att
//
LOCUS       DAVAZV010000027        25336 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVAZV010000027 DAVAZV010000000
VERSION     DAVAZV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25336
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.027"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..309)
                     /locus_tag="VQT46_001102"
     CDS             complement(<1..309)
                     /locus_tag="VQT46_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HET2371139.1"
                     /translation="MKKKWMYYAACSSNESADDSSSDKGDGGSLVVYSPNSEGLIGAT
                     IPAFEEKYGIKIELIQAGTGELFKKLESEKEVPVADIIFGGSYTQYATHGELFENYIS
                     K"
     gene            complement(897..1673)
                     /locus_tag="VQT46_001103"
     CDS             complement(897..1673)
                     /locus_tag="VQT46_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET2371140.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            1795..2541
                     /locus_tag="VQT46_001104"
     CDS             1795..2541
                     /locus_tag="VQT46_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2371141.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2554..3534
                     /locus_tag="VQT46_001105"
     CDS             2554..3534
                     /locus_tag="VQT46_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET2371142.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            3729..4049
                     /locus_tag="VQT46_001106"
     CDS             3729..4049
                     /locus_tag="VQT46_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2371143.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4095..4403
                     /locus_tag="VQT46_001107"
     CDS             4095..4403
                     /locus_tag="VQT46_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2371144.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4420..5718
                     /locus_tag="VQT46_001108"
     CDS             4420..5718
                     /locus_tag="VQT46_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2371145.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQTLGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVITQLVILAMSTLVYFPFFKVQDRLAYQNEIKQS"
     gene            5869..8307
                     /locus_tag="VQT46_001109"
     CDS             5869..8307
                     /locus_tag="VQT46_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET2371146.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMTIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8326..8994
                     /locus_tag="VQT46_001110"
     CDS             8326..8994
                     /locus_tag="VQT46_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET2371147.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9012..10100
                     /locus_tag="VQT46_001111"
     CDS             9012..10100
                     /locus_tag="VQT46_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET2371148.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            10555..13056
                     /locus_tag="VQT46_001112"
     CDS             10555..13056
                     /locus_tag="VQT46_001112"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET2371149.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAWLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLIRSKEIVAENNGALD
                     KVYNETVKAVTEQIDSLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVTWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVISVPNKLVNIVVK"
     gene            13250..13945
                     /locus_tag="VQT46_001113"
     CDS             13250..13945
                     /locus_tag="VQT46_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371150.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMLARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYESLREL"
     gene            13957..14373
                     /locus_tag="VQT46_001114"
     CDS             13957..14373
                     /locus_tag="VQT46_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371151.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(15000..15092)
                     /locus_tag="VQT46_001115"
     CDS             complement(15000..15092)
                     /locus_tag="VQT46_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET2371152.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            15253..16224
                     /gene="ruvB"
                     /locus_tag="VQT46_001116"
     CDS             15253..16224
                     /gene="ruvB"
                     /locus_tag="VQT46_001116"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET2371153.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            16205..16777
                     /locus_tag="VQT46_001117"
     CDS             16205..16777
                     /locus_tag="VQT46_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET2371154.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            17008..17766
                     /locus_tag="VQT46_001118"
     CDS             17008..17766
                     /locus_tag="VQT46_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET2371155.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            17775..18578
                     /locus_tag="VQT46_001119"
     CDS             17775..18578
                     /locus_tag="VQT46_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET2371156.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            18600..19859
                     /gene="rseP"
                     /locus_tag="VQT46_001120"
     CDS             18600..19859
                     /gene="rseP"
                     /locus_tag="VQT46_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET2371157.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            19872..21725
                     /locus_tag="VQT46_001121"
     CDS             19872..21725
                     /locus_tag="VQT46_001121"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET2371158.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            21825..23204
                     /gene="bglA"
                     /locus_tag="VQT46_001122"
     CDS             21825..23204
                     /gene="bglA"
                     /locus_tag="VQT46_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2371159.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNELIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIHDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            23396..25204
                     /gene="glmS"
                     /locus_tag="VQT46_001123"
     CDS             23396..25204
                     /gene="glmS"
                     /locus_tag="VQT46_001123"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET2371160.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEDGLSVLEAFKKALHIIRGSYAFAL
                     IDSENPDVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
BASE COUNT         7735 a         4313 c         5537 g         7751 t
ORIGIN      
        1 ttttgaaata tagttttcaa agagttctcc gtgggtagca tattgtgtat aagaaccacc
       61 aaagataata tcagctacag gaacttcttt ttctgactct agttttttga aaagttctcc
      121 agtaccagct tgaatcagtt ctattttgat accatatttt tcttcaaagg caggaatagt
      181 tgctccaatt aagccttctg agtttggtga ataaacgact agcgaaccac cgtctccttt
      241 atcagatgaa ctgtcatcgg cagattcatt agaagaacaa gcagcataat acatccattt
      301 ctttttcatg atggatacct ccgttgtgtt atttaagttt attttaaaac aatgtaagcg
      361 tttttaaaac ctacaattct attctatagt gtattgaatc tataacagta cacattgact
      421 gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcac atcttatttc
      481 aattcactat attagagtaa aattctctac aaaaaaaaag aatagcctat tttactattt
      541 ttccgagtga tttcaattcc tttggggaaa tatggagata ctttttaaat cctgacaaat
      601 ggttgtttct ttttctaaat cggtgatact gtatcggaga atgcgcgtga ggtcacaaag
      661 gctgcgatag agcttctatg gagaatttct ttttggagag attttttaaa ggaatgagac
      721 atccgctacc tccttggaag gtttttttgt gataagtata gcagtttaaa aattctagag
      781 caaggtaaaa tagaaaaggt ttggctaaaa ttttttagct aaaccttttg aaaagttaag
      841 tatgtattat agatgcttgt tatctgcaaa tagctagagc atttcaagga aataaactag
      901 aaataacaat taatatggtg gttcagaaat accttttgat aatcaataag atcttcagga
      961 tgaagtgcgt tgattccatc catttcatat ttccgattta ataaacgata tttgttttca
     1021 ccaaattgat gaaaagggag tagttgaact tggtcgatat ttaatgagtt aaatagagta
     1081 gcgaattttt ctgcatcctc taaactattg ttaaaattag gaataactgg gattcttaaa
     1141 acgatagttt tattttgtga aaaagcataa tgaatgtttt taataatcat ttgattaaaa
     1201 accccagtca cttttttatg ttttatagaa ttataatgtt ttaggtctgt gtagataaaa
     1261 tccacatatt gaattaaatc aataaatttt tcatgatcaa caaaggcagt agtttcaatg
     1321 gcagtgtgta tgtgatgttc tttagctgat tttaagatag ctttagcaaa ttcaaactga
     1381 gcaaatattt cacctcctga taaagttaaa cctccaccgg attcttcgta aaattctttg
     1441 tcttttaata cctctgtaat aatttcttct acagtctttt cttcaccgac taaggtgaat
     1501 ttctctcgtt gagcatcttt cattttttca ggtttcattc tttgagattc aggattagaa
     1561 caccatggac agcgcagagg acatcctttt aaaaaaacag ttgtacgaat acccgggccg
     1621 tcatgaattg aaaagtgttg aatattaaaa ataattcctt tagatatttc cataagagtt
     1681 cctcctcttc ataagtctat cctatcacaa aaacgaaaga aaaacaatta cgaacgaaag
     1741 gttaatttgt tgttttttgc tttttatttt ggtagaataa aacggaggtg taaaatgaaa
     1801 agattggaac aaattattaa attagtatca gaatatgaaa agatcgacgt taatacatta
     1861 tcggaaaaat taaatgtatc gaaagtaacg attagaaaag atttagataa attagagtca
     1921 aaaggtttat tacacagaga gcatggatat gctgtattaa atagtggaga tgacttaaat
     1981 gtacgtttgt caattaatta tgaaattaag agaaaaattg ttcaggaagc agtaaaattg
     2041 gtgtcagata atgaaacgat aatgatagaa tctggatcga cctgtgcttt acttgctgag
     2101 gaaatttgca agcaaaaaag aaatgttacg attgtaacaa attcattttt tatagcaaat
     2161 tttgtgagag cttatgattc atgtcgtatt attgttcttg gtggagagtt tcagaaggat
     2221 tcacaggtta ctgtgggacc tttattaaaa gaaatgatac agacttttca tgtgcatcaa
     2281 gcttttgttg ggacagatgg atacgataaa gagatgggct ttacaggaaa agatttaatg
     2341 cgcagtgagg tagttcaata tatttcagca gcgtcggata aagtcattgt cctaactgac
     2401 tcaagtaaat ttgataaaag gggtacagta agaagatttg ctttaagtca agtctatgaa
     2461 gtaataacag acgaaaaact ttctaaacaa aatatagcta cattagaaaa tgctgggata
     2521 atggttaagg tagtttcgta agaggttaag tgtatgaatc aagataggaa taaactgctc
     2581 tctaaaattg cttatctgta ttatattgaa aacttaaatc agtcacaaat agcagcaaaa
     2641 ttaggaattt atagaacctc tattagtaga atgttaacag aagcaaggaa tgcaggaatt
     2701 gttaaaattg aaatagagaa ttttgatacc aatatgttta agttggaaaa ttatgtaaaa
     2761 gaaaaatatg gtctggaaag tttagaaatt attccaaatg aatttgatga taatccaaca
     2821 attttatctg aaagaatttc tcaagttgca gcaggtgtcc ttaggaatct aattgatgat
     2881 aatatgaaaa ttggcttttc ttgggggaaa agtttaagta atttagtaga tttaattcac
     2941 agtaaaagtg tccgaaatgt tcacttctat cctctagcag gtggtcctag tcacatacac
     3001 gctaaatacc atgtgaatac actgatttat gaaatgtcta gaaaatttca tggagagtgt
     3061 acatttatga atgcaacgat tgtgcaagaa aataaattgt tagcagatgg tattttgcaa
     3121 tcaagatatt ttgaaaattt gaaaaatagt tggaaagatt tagatatagc tgtagtcgga
     3181 attggtgatt ttagcaataa aggaaagcat caatggttag acatgcttac agaggatgac
     3241 tttaaagaat tgaccaaagt taaaactgta ggagaaattt gttgtcgatt ttttgattca
     3301 aaaggtaaag aagtctatga aaacttacag gaaagaacga tagcaatctc tttggaagat
     3361 ttaaaaaata ttcctcaaag tttagctgtt gcttacggtg atacgaaagt atcttcgatt
     3421 ctttctgtct tgcgtgctaa tttagtaaat catttgatta cagacaaaaa tacaatttta
     3481 aaagttttgg aagaagatgg ggatttgact tttagagaga ttctaggtga gtgaaaatga
     3541 tagactgatt cagtttatcg tttttctttt tagttgattg cacatttgtg cttatataaa
     3601 caaaaatagt ttatctgttg tttttggatt gacaacttta ttatgtagtt gtattctata
     3661 gttacaaaag aaaattttaa aatttcaaat gaaaaaagct ttttacatag tgaaatgagg
     3721 aggaatttat ggaaattatt gttccagatc aaattatcat gggtttaatt ttatatgctg
     3781 gtgatgcgaa acaacatatt tataaagcgt tagattacat aaaaaatggt acatgtgaac
     3841 ggtgtgaaga agaaatccag ttagctgatg ccgccttatt agaagcccat aatctacaaa
     3901 caaaattctt ggcacaagaa gcgtctggta caaagacaga aattacagct ctctttgttc
     3961 attcacaaga tcatctcatg actagtatga cggagattaa tttaatcaaa gaaattatta
     4021 gtttgagaaa agaacttcat aaaaaataat actagagtat tatcattgtt attaacatag
     4081 aggaggaaaa cataatggtg aagattggtt tgttttgtgc agcaggtttt tctactggta
     4141 tgcttgtaaa taatatgaaa attgcagcgc aatctagtgg agttgaggca gaaatagagg
     4201 cgttttctca gtctaaatta gcggattatg cgccaaatat agatgttgca ctattgggtc
     4261 cacaagttgc ttatacatta gataaatcaa aagaaatttg tgataagtgt gatgttccga
     4321 tagctgttat tccgatgatg gactatggta tgttagatgg gaaaaaagta ttagatttgg
     4381 ccctatcttt gattagtggg taagaaaagg agatttatta tgtcaaagat ggatgttcag
     4441 aaaatcattg caccgatgat gaagtttgtg aatatgcgtg gcattatagc tctaaaagat
     4501 gggatgttag caattttgcc attgacagta gttggtagtt tgttcttgat tatgggacaa
     4561 ttgccgttcg aaggattaaa taagagcatt gctagtgttt ttggagctaa ttggacagag
     4621 ccgtttatgc aagtatattc aggaactttt gctattatgg gtctaatttc ttgtttttca
     4681 attgcctatt cttatgctaa gaatagcgga gtagaggctt taccagctgg agttctatct
     4741 gtatctgcat tctttatttt gctaagatca tcttatatcc ctaaacaagg tgaggcgatt
     4801 ggggacgcta ttagtaaagt ttggtttgga ggccaaggaa ttatcggtgc tatcattata
     4861 ggtttggtag taggaagtat ttataccttc tttataaaga gaaaaattgt tattaagatg
     4921 ccagaacaag ttccacaagc tattgccaaa cagtttgaag caatgattcc agcatttgta
     4981 attttcttat cttctatgat tgtatatatt ttagcgaagt cattgactaa tggcggaaca
     5041 ttcatagaaa tgatttattc tgctattcaa gttccgttgc aaggtttaac tggatctttg
     5101 tatggtgcta ttggaattgc attctttata tcatttttgt ggtggtttgg tgttcatggg
     5161 caatcggtag taaatggagt agtgacagct ctgcttttat ctaatcttga cgctaataaa
     5221 gctatgttag cctctgctaa tctatcatta gaaaatggtg cacatattgt tactcaacaa
     5281 tttttagatt catttttaat tctatcaggt tcagggatta cgtttggtct tgtagttgcc
     5341 atgctttttg cagcaaaatc aaaacaatac caaaccttag gaaaagttgc agcttttcca
     5401 gcaatattta acgtaaatga gccagttgta tttggatttc cgattgtcat gaatccagtt
     5461 atgtttgtac ctttcattct tgttcctgta cttgcagctg tgatagtata tggagctatt
     5521 gcaacaggtt tcatgcagcc attctcaggg gtaacattgc cttggagtac accagctatt
     5581 ttatcaggat ttttggtggg tggatggcaa ggagttatta ctcagctggt gatattagcg
     5641 atgtctacat tggtttattt tccattcttt aaagtacagg atcgtttagc ttaccaaaat
     5701 gaaatcaaac aatcttagag gtatttgtgt gttactgtta aactcacaca tttgtgctaa
     5761 aaattagaga gttaaaattt ttctagttaa aagcttgaaa atttctataa aaatcggtat
     5821 tatattttcg aaagaaataa aaatattttc gaaagaaagg tggttacgat ggtaaataca
     5881 gaagtagcaa gaacaacaat caagacagaa tattttggca gccttactga aaggatgaac
     5941 aaatatcgag aagatgtttt aaataaaaaa ccttatattg atgctgagag agcagttcta
     6001 gcaacacgcg cctatgaacg atacaaggaa caacctaatg tcctaaaacg tgcatatatg
     6061 ctgaaagaaa ttttggaaaa tatgactatc tatattgaag aagaatctat gattgcggga
     6121 aatcaagctt cttccaataa agatgctcct atttttccgg aatatacgct agaatttgtt
     6181 ctcaatgagt tggatctttt tgaaaagcgt gatggagatg ttttctatat tacagaagaa
     6241 acaaaagaac aacttagaag tattgctccg ttttgggaaa ataataattt acgtgctaga
     6301 gctggtgcct tattacctga agaagtgtct gtttatatgg aaacaggatt cttcggtatg
     6361 gaaggtaaga tgaattctgg agatgctcac ctagcagtta actatcagaa acttttgcaa
     6421 tttggtttaa gaggttttga agagcgggct cgtaaagcaa aagtagctct agatttaaca
     6481 gatccagcaa gtattgataa atatcatttt tacgactcta tatttatcgt aatcgatgct
     6541 attaaagtat atgcaaagcg ctttgttgct cttgctaaaa gtttagccga aaatgcaaat
     6601 cctaaacgta agaaagaatt acttgagatt gcagatattt gctctagagt cccatatgaa
     6661 ccggcaacta cttttgcaga agctattcaa tcagtttggt ttattcaatg tattttacaa
     6721 attgaatcta atggccactc tctttcatat ggccgttttg atcaatatat gtatccatat
     6781 atgaaggctg atttagaaag tggtaaagaa acagaagata gcattgttga acgtctgaca
     6841 aatctttgga ttaagacaat tacaatcaat aaggttcgca gtcaatcaca tacattttct
     6901 tcagcaggaa gtcctttata tcaaaatgtt acaattggtg gacagactcg agataagaag
     6961 gatgctgtta acccattatc ttatttggta ttaaaatcag ttgcacaaac ccatctaccg
     7021 caacctaatc taactgtacg ttaccatgca ggtttagatg ctcgtttcat gaatgagtgt
     7081 attgaagtga tgaaacttgg ttttggtatg cctgcattta ataatgatga gattattatt
     7141 ccttctttta ttgcaaaagg agtattggaa gatgatgctt atgattacag tgccattgga
     7201 tgtgttgaaa cggcagttcc agggaaatgg ggctatcgtt gcacaggtat gagttatatg
     7261 aacttcccta aggttctact tatcacgatg aatgatggaa ttgatccggc ttcgggtaaa
     7321 cggtttgcac caagctttgg tcattttaag gatatgaaga acttttctga attagaaaat
     7381 gcttgggata aaacactaag atatttgaca cgaatgagtg ttattgttga aaattctatt
     7441 gatttatcat tggaacgaga agttcctgat attctatgtt cagcattgac tgatgattgt
     7501 attggtcgtg gaaaacacct taaagaaggt ggagcagtat atgattatat atcaggattg
     7561 caagttggaa ttgcaaattt gtcggattca ttagctgcaa ttaaaaaatt ggtgtttgag
     7621 gaagaacgta taagcccaag tcagctttgg catgcactgg aaacagatta tgccggagaa
     7681 gaaggtaagg tcattcaaga aatgttgatt catgatgcac ctaagtatgg taatgatgat
     7741 gattatgctg acaaattggt tactgctgct tatgacattt atgttgatga aattgctaaa
     7801 tatcctaata cacgttatgg aagagggcct attggaggaa ttcgttattc aggaacatct
     7861 tctatctcag ccaacgtagg gcagggacgt ggaacattag caactccaga tggacgcaac
     7921 gcgggtacac cgttagcaga gggttgttca ccatcacata atatggatca acacggccct
     7981 acatctgttt taaaatctgt ttcaaaatta ccaacagatg aaatcgtagg tggggttctc
     8041 ttaaatcaga aagtaaatcc tcaaacgtta gccaaagaag aagataaatt aaaactaatt
     8101 gctttgttac gaacattctt taatcgttta catgggtacc atattcaata caatgttgtt
     8161 tccagagaga cgttgattga cgctcagaaa catcctgaaa aacacagaga cttaattgtt
     8221 cgtgttgcag gatactctgc attcttcaat gttctttcta aggcaaccca agatgacatt
     8281 ataggacgta ctgagcatac tttgtaaaat aaagaggttc tttttatgga atttatgctt
     8341 gacacattaa atttagatga gattaaaaag tggtctgaaa ttttgccgct agctggggta
     8401 acttcaaatc ccactattgc aaaaagagag ggttctatta atttttttga acgaatcaaa
     8461 gatgtaagag aattgattgg ctctacaccc tctattcatg ttcaggtgat ttctcaagat
     8521 tttgaaggca tcttaaagga tgctcatgaa attcgaagac aagcaggaga tgatatattt
     8581 atcaaagtac ctgttactcc agctggatta cgtgcaataa aggtgctaaa aaaagagggc
     8641 taccatatca ctgcaacagc tatttataca gttattcagg gattattagc tatcgaagta
     8701 ggagcggatt acctagctcc atattataat agaatggaaa atctgaacat tgattcaaat
     8761 tctgtcattc gtcaattagc tcttgctatt gatagacaga actctcctag taagatttta
     8821 gctgcatcct ttaaaaatgt agcacaagta aataatgctt tagctgcagg tgcgcatgct
     8881 gttacagcag gagcagatgt ttttgaatca gctttcgcca tgccatctat ccaaaaggcg
     8941 gttgatgatt tttctgacga ttggtttgtt actcaaaata gtcgttccat ttagatagag
     9001 aggaaataca tatgagaatt tttgctagtc cttctagata tattcagggg gaaaatgcct
     9061 tgtttgaaaa tgccaaatca attttggatt tgggaaatta ccctattcta ttatgcgatc
     9121 agttggttta tgatattgtt ggaaaacgat ttgaagatta tctacatagg tatggtttcc
     9181 atattgttct ggcgctattt aatggtgaag cttctgacaa tgaaatcaat cgagttgttg
     9241 ccttggctga gaaagaaaat tgtgatagta ttatcggtct tggtggggga aagacgattg
     9301 atagcgcaaa agctattgca gatttgattg aaaagcctgt tattattgct ccaacaattg
     9361 catcgaccga cgcacctgta tctgctttat ctgttattta tacagatgaa ggtgcatttg
     9421 atcattatct attttattct aaaaatccag atttagtttt ggttgataca aaagttattt
     9481 cacaagcccc taagcgttta ttagcgtctg gtattgcaga tggtttagca acttgggttg
     9541 aggcgcgtgc ggttatgcag gcaaatggaa aaactatgtt gggacaacag caaacattgg
     9601 ctggagttgc aattgcgaag aaatgtgaag aaacgctgtt tgcagatggt ttacaggcta
     9661 tggcagcttg tgaagctaaa gtggtgacac cagcattaga aaatattgtt gaagctaata
     9721 ctttattgag tggcctaggt tttgaaagtg gaggattagc tgcggcgcat gcaattcata
     9781 atggttttac tgcattgaca ggtgacattc atcatttaac acatggtgaa aaagtagctt
     9841 atggaacttt agtacaacta ttattggaaa atagacctaa agaagaactt gataagtata
     9901 ttgagtttta caaaaaaatt ggtatgccaa caactctaaa agaaatgcat ttggatcaag
     9961 ttggatatga tgatttaata aaagttggta aacaagcaac tatggagggt gagacaattc
    10021 atcagatgcc gtttaagatt tcgccttcag atgttgctca agctattatc gctgtagatg
    10081 cctatgtaaa ttcaaaataa acaataagga ctactgtttt ccaaatggta gtcttttatt
    10141 gatcctcgta ttgaattcta tagcagattg aaataagatg agaacaaatc gattgggaaa
    10201 gtaaaattaa tttctataag tattttagca attgtttcgt actatttcag attcagtcca
    10261 ctatacgttc ttcataaatc aaaaagcgac ataggttgtc ggctatttat tgtgaataca
    10321 ttaattagca ttccagtttt atcttcggtc taaaataagt attttgtgct atacgagata
    10381 agtttcttga cttactcctt gatttactgc ataacaatgg gataaaaagt gggagataga
    10441 gcaattcata gtcatcaaaa ttaatgagat acagtataca gtttttcctt taaacacatt
    10501 tcaaattccc tcaaaaatgg tataatagta acatcacaaa attggagaga gaccatgagt
    10561 ttttacaatc ataaagaaat tgagcctaag tggcagggct actgggcaga acatcataca
    10621 tttaagacag gaacagatgc atcaaaacct aagttttatg cgcttgatat gttcccttat
    10681 ccgtctggag ctggtctgca cgtaggacac ccagaaggtt atactgcaac cgatatcctc
    10741 agtcgttaca aacgtgcgca aggctacaat gtccttcacc caatgggttg ggatgctttt
    10801 ggtttgcctg cagagcaata cgctatggat actggtaatg acccagcaga atttacagcg
    10861 gaaaacattg ccaacttcaa acgtcaaatc aatgcgcttg gattttctta tgactgggat
    10921 cgtgaagtca acacaacaga tccaaactac tacaagtgga ctcaatggat tttcaccaag
    10981 ctttacgaaa aaggcttggc ctatgaagct gaagtgccag taaactgggt tgaggaattg
    11041 ggaactgcca ttgccaatga agaagtgctt cctgacggaa cttctgaacg tggaggctat
    11101 ccagttgtcc gcaaaccaat gcgccaatgg atgctcaaaa tcacggctta cgcagagcgc
    11161 ttgctcaatg acttagatga actagattgg tcagagtcta tcaaggatat gcaacgcaac
    11221 tggattggta aatcaactgg tgccaatgta actttcaaag taaaaggaac agacaaggaa
    11281 tttacagtct ttactactcg tccggacaca cttttcggtg cgactttcac tgttttggct
    11341 cctgaacatg aattagtaga tgccatcaca agcacagagc aagcagaagc agtagcagac
    11401 tacaaacacc aagccagcct taagtcagac ttggctcgta ccgaccttgc caaagaaaaa
    11461 actggtgtat ggactggtgc ttatgccatc aatcctgtca atggtaagga aattccaatc
    11521 tggattgcgg attacgttct tgctagctat ggtacaggtg cggtaatggc tgtgcctgcc
    11581 cacgatcaac gtgactggga atttgccaaa caatttgacc ttccaatcgt cgaagtactt
    11641 gaaggtggaa atgttgaaga agctgcctac acagaagatg gccttcacgt taattcagac
    11701 ttcctagatg gactcaacaa agaagacgct attgccaaga ttgtggcttg gttggaagaa
    11761 aaaggctgtg gacaagagaa ggtaacctac cgtctccgcg actggctctt tagccgtcaa
    11821 cgttactggg gtgagccaat cccaatcatt cattgggaag atggaacttc aacagctgtc
    11881 cctgaaagtg aattgccact tgttttgcct gtaaccaagg atatccgtcc ctcaggtact
    11941 ggtgaaagtc cactagctaa cttgacagac tggcttgaag tgactcgtga agatggtgtc
    12001 aaaggtcgtc gtgaaacaaa tactatgcca caatgggcag gttcaagctg gtactacctc
    12061 cgctatattg acccacacaa tactgagaaa ttggctgacg aggatctgct caaacaatgg
    12121 ttgccagtag atatctacgt gggtggtgcg gaacatgctg tacttcactt gctttacgct
    12181 cgtttctggc ataaattcct ctatgacctc ggtgttgttc caactaagga accattccaa
    12241 aaactcttta accaaggaat gattttggga acaagctatc gtgaccaccg tggggctctt
    12301 gtggcgactg acaaggttga aaaacgtgat ggttctttct tccatgtgga aacaggggaa
    12361 gagttggagc aagcgccagc caagatgtct aaatcgctca agaacgttgt caacccagac
    12421 gatgtggtgg aacaatacgg tgctgatacc cttcgtgtct atgaaatgtt catgggacca
    12481 ctcgatgctt cgattgcttg gtcagaagaa ggtctggaag gaagtcgtaa gttccttgac
    12541 cgtgtttacc gtttgattag aagtaaggaa attgttgcgg aaaacaatgg cgctcttgac
    12601 aaggtttaca acgaaactgt taaagctgtc acagagcaaa ttgattccct caaattcaac
    12661 acagccattg cccaacttat ggtctttgtc aatgcggcta acaaggaaga caagctctat
    12721 gttgactatg ccaaaggatt tatccaattg attgccccat ttgcacctca cttggcagaa
    12781 gaactctggc aaactgttgc tgcaacaggt gagtcaatct cttacgtgac ttggccaaca
    12841 tgggacgaaa gtaaactggt tgaagacgaa atcgaaatcg ttgtccaaat caaaggtaaa
    12901 gtccgtgcca aactcatggt cgctaaagac ctatcacgtg aagaattgca agaaattgct
    12961 ctagcggatg aaaaagtcaa agcagaaatt gacggtaagg aaatcgtgaa agtgattagt
    13021 gtaccaaata aattggttaa tattgttgta aaataaccaa tttatttgct gatttccaac
    13081 ctcaaacagt ttcccaaact gtttgagcca actaaactcg ttaatatcgt tgtgaaataa
    13141 ggtaggaatc cttcagagta gaatctggag gattttttga atcttcttat gaaagtatgg
    13201 tatactatgg gcaactataa agtttgaaaa gtgaaaaaag gagaaagcta tgccagtaaa
    13261 tgaatatggt caaatgattg gggagtcaat ggaaggttat acaccaggtg aactgccttc
    13321 tattgatttc ttagaagggc gttatgctag gatagaggct ctttcagtgg aaaagcatgc
    13381 ggaggatttg ctagctgttt atgggcctga tacgcctcag gagatgtgga cctacctttt
    13441 tcaggagcca gtagcagata tgggggagct ggttagcctt ttacatcaga tgttggctcg
    13501 taaggaccgt ttttactatg caatcataga caaggcgact ggtaaggctt tgggatcttt
    13561 ttctctcatg cgcattgacc agaataaccg agtaatagaa gtcggagcag tcactttttc
    13621 tccagagcta aggggtacac ggataggaac tgaagctcag tatctcctag ctcgctatgt
    13681 ttttgaggag ctaaactatc gtcgctacga gtggaaatgc gatgccttaa atctgccatc
    13741 cagacgagct gcggagcgtt tgagctttat ttatgaagga accttccgtc aggcagtggt
    13801 ttataaggga cgtacgagag atacggattg gttgtctatg attgataagg actggcctca
    13861 agtcaaagat cgtttggaaa catggttgcg tcctgaaaat tttgataaaa atggacagca
    13921 gtacgagagc ttgagagaac tttaagaggt gttgagatga ttactattaa aaagcaagaa
    13981 attgtcaagc tagaggatgt tttacatctc tatcaggctg tcggttggac aaattatacc
    14041 catcaaccag agatgctgga gcaggcctta tctcattcat tagtaattta tctggcactt
    14101 gatggtgatg ctgtggtggg cttgattcgt ttggttggag atggattctc atcagtattg
    14161 gttcaggatt taatcgtttt accaatctat cagcgtcaag gaattggtag tgccttgatg
    14221 aaagaggctt tagaggatta caaagatgcc tatcaagtcc agctggtgac agaagagaca
    14281 gaaagaacct tgggcttcta tcgttctatg ggctttgaaa tcttatccac ctataattgt
    14341 atagggatga cttggatgaa tcgtaaaaaa taacaaaact tgttttttct taagcaaaat
    14401 ttaaggatgg tctagtatta tatagtcatt aaataaagac ctcctaactt tatttaataa
    14461 aatcctaaac ttttcttttt cataataatc tcccttaact ccacccaatc aggtggagtt
    14521 ttttagctct atttcaggct tttggggact attctaaaaa taatttttcg atatttttcg
    14581 gtatttttcg gattttggtc ggggaattgg cggggacttt tttagcgaat ataactaaga
    14641 aataggtctg tggtcgcttc agctagttca aactcaattt gattgtaagt gactgttaat
    14701 tgaagaactg gaactactgt aataatgatt ttgcttgtct agtagtggcg tattaaatga
    14761 gaagtgacat gtaagattgt ctcttcgttt acgaaatcaa aatttctatg aaattgatag
    14821 aatccctaac gttctcttaa tcttaaccgt cttgtcgtac agcggttgaa gaaaatgtaa
    14881 acctttgaca aaattcgtga actatgggat aataaaaagg aattgagtac tagttctata
    14941 tcataggcta gaaaagaccc caagctcacg accaaataag cttgaggtct tttttgacac
    15001 tatttgtcct tgtttagcca tttatcgact atacgaagaa cgacaccgac cacaattggt
    15061 ccgatgatag ttttgagtac taattccatc atgggctatc tcacctcctt tcgtaggcgg
    15121 tgtagcagtg tcgtagaata ttataccaca taagtgctaa acttaggagt cacccaatca
    15181 ggtggctttt ttgtttgtgg cttggttttt tgatataata gagccatgag tagaatttta
    15241 gataatgaga taatggggga tgaggagtta gtagaacgca cgctccgtcc tcagtattta
    15301 cgtgaatata tcggacagga taaggtcaag gaccagctac aaatctttat tgaagctgcc
    15361 aaaatgcggg atgaagcgct ggatcatgtg ctcttatttg ggcctccagg tctcgggaaa
    15421 acgaccatgg cctttgttat tgccaacgaa ctgggagtca atcttaagca gacgtcgggt
    15481 ccagtcattg aaaaagccgg agatctggta gctattttga atgagttaga gcctggggat
    15541 gtacttttta ttgatgagat ccatcgtttg ccaatgtcag tggaagaggt gctttatagt
    15601 gctatggagg acttctacat agatattatg attggggctg gtgagggtag tcgtagtgtt
    15661 catttggagt taccaccttt taccttgatt ggtgcgacga ctcgggctgg tatgctctcc
    15721 aatccgctac gggcacgttt tgggattaca ggccatatgg agtattatgc ccatgctgac
    15781 ttgacagaaa ttgtcgagcg gacggcagat atttttgaga tggaaatcac tcatgaggca
    15841 gcatctgagt tggccctacg tagtcgtggg acccctcgta ttgccaatcg tctcctcaag
    15901 cgcgtgcgcg attttgccca gataatgggg aatggggtaa ttgatgatat tattaccgat
    15961 aaggctttga ctatgctgga tgttgaccat gaaggtttgg actatgtgga tcaaaaaatc
    16021 cttcgtacca tgattgagat gtacagtgga ggacctgttg gtctaggaac tctttctgtg
    16081 aatatcgccg aagagcgtga gacagttgaa gatatgtatg agccttactt gattcaaaaa
    16141 ggttttatca tgcggacacg gtctggacgg gtggcgactg ctaaggcata tgagcactta
    16201 ggttatgaat acagtgaaaa ataagcaaga aatcttagag gcttttagag aaaatccaga
    16261 tatgatggcc attctgacga tcatccgaga ccttggtctg aaagactcgt ggttggcagc
    16321 aggttctgtc agaaatttca tttggaatct tttgtcagac aaatcccctt ttgatcatga
    16381 aacagatata gatgtgattt tctttgatcc agatttttct tatgaggaaa ccttattact
    16441 ggagaaaaag ctgagagagg attttcctca gtaccagtgg gaattgaaaa atcaggtcta
    16501 tatgcatcag cacagtcctc acactgcttc ctataccagt tctcgtgatg ctatgagtaa
    16561 gtatccagaa cggtgtacgg cagttggact gcgcttgaat gaagaatcag attttgaact
    16621 ctatgcacct tatggtttgg aggatatttt gaattttcaa gttcgtccaa ctcctcattt
    16681 cttagaaaat gaagaccgaa tggaactcta tcaaacacgt ttatccaaga aaaattggca
    16741 ggagaaatgg aaaaatttga tttttaaaaa tacttaagga aactttaagc tagggagtgt
    16801 acactaagtt cataagttaa gaagacctta acttaaactc ctaaaacttt ttcataataa
    16861 tctccctata aaaataaagt cgcccaatca ggcggcttat ttttttgaaa aatgggcatg
    16921 gtgcctgaga ataaatagct tagtgataga agaaaatggg gaaatatggt ataatgaaac
    16981 gatagatttt tgaataggaa taagatcatg tttggatttt ttaagaaaga taaggctgtg
    17041 gaagtagagg ttccgacaca ggttcctgct catatcggca tcatcatgga tggcaatggc
    17101 cgttgggcta aaaaacgtat gcaaccgcga gtttttggac ataaggcggg catggaagca
    17161 ttgcaaaccg tgaccaaggc agccaacaaa ctgggcgtca aggttattac ggtctatgct
    17221 ttttctacgg aaaactggac ccgtccagat caggaagtca agtttatcat gaacttgcca
    17281 gtagagtttt atgataatta tgtcccggaa ctacatgcga ataatgttaa gattcaaatg
    17341 attggggaga cagaccgcct gcctaagcaa acctttgaag ctttaaccaa ggctgaggaa
    17401 ttgactaaga acaacacagg attgattctt aattttgctc ttaactatgg tggacgtgct
    17461 gagattacac aggcgcttaa gttgatttcc caggatgttt tagatgccaa aatcaaccca
    17521 ggtgacatca cagaggaatt gattggtaac tatctcttta ctcagcattt gcctaaggac
    17581 ttacgagacc cagacttgat tatccgtact agtggagaat tacgtttgag caattttctt
    17641 ccatggcagg gagcctatag tgagctttat tttacggaca ccttatggcc tgattttgac
    17701 gaagcggcct tgcaggaagc tattcttgcc tataatcgtc gtcatcgccg atttggagga
    17761 gtttaggagg aaatatgacc caggatttac agaaaagaac cttgtttgca gggattgccc
    17821 tggctatttt cctaccaatt ttaatgattg ggggcctctt gcttcagata gcaatcggaa
    17881 tcatagccat gctagccatg catgaacttt tgaagatgag aggtctagag accatgacga
    17941 tggagggcct cttgaccctc tttgcaacct ttgcattgac cattcccttg gagaattacc
    18001 tgactttttt gccagttgat gggaatgtgg ttgcctatag tgttttgatt tcaatcatgt
    18061 taggaacgac cgtttttagc aagtcttata cgattgagga tgcggttttc cctcttgcta
    18121 tgagcttcta cgtgggcttt ggatttaatg ctttactaga tgctcgtgtt gcaggtttgg
    18181 acaaggctct cttagccttg tgtatcgtct gggcgacaga cagtggtgcc tatcttgttg
    18241 ggatgaacta tgggaaacga aagttagcac caagggtatc gcctaataaa acccttgagg
    18301 gtgccttggg tggtatttta ggagcaattt tagtaaccat tatctttatg atagttgaca
    18361 gtacagttgc tcttccatat ggaatttaca agatgtcagt ctttgctatt ttctttagca
    18421 ttgctggaca atttggtgat ttactagaaa gttcgatcaa acgtcatttt ggtgttaagg
    18481 attctgggaa atttatccct ggacatggtg gtgttttgga tcgtttcgat agtatgttgc
    18541 ttgtatttcc aatcatgcac ttatttggac tcttttaatc aaaagacgga ggaaacgcta
    18601 tgctcggaat tttaaccttt attctggttt tcgggattat tgtagtggtg cacgagttcg
    18661 ggcacttcta ctttgccaag aaatcaggga ttttagtacg tgaatttgcc atcggtatgg
    18721 gacctaaaat ttttgctcac attggcaagg atggaacggc ctataccatt cgaatcttgc
    18781 ctctgggtgg ctatgtccgc atggccggtt ggggtgatga tacaactgaa atcaagacag
    18841 gaacgcctgt tagtttgaca cttgctgatg atggtaaggt taaacgcatc aatctctcag
    18901 gtaaaaaatt ggatcaaaca gccctcccta tgcaggtgac ccagtttgat tttgaagaca
    18961 agctctttat caaaggattg gttctggaag aagaaaaaac atttgcagtg gatcacgatg
    19021 caacggttgt ggaagcagat ggtactgagg ttcggattgc acctttagat gttcaatatc
    19081 aaaatgcgac tatctggggc aaactgatta ccaattttgc aggtcctatg aacaatttta
    19141 tcttaggtgt cgttgttttt tgggttttaa tctttatgca gggtggtgtc agagatgttg
    19201 ataccaatca gttccatatc atgccccaag gtgccttggc caaggtagga gtaccagaaa
    19261 cggcacaaat taccaagatt ggctcacatg aggttagcaa ctgggaaagc ttgatccaag
    19321 ctgtggaaac agaaaccaaa gataagacgg caccgacttt ggatgtgact atttctgaaa
    19381 aggggagtga caaacaagtc actgttacac ccgaagatag tcaaggtcgt taccttctag
    19441 gtgttcaacc gggggttaag tcagattttc tatccatgtt tgtaggtggt tttacaactg
    19501 ctgctgactc agctctccga attctctcag ctctgaaaaa tctgattttc caaccggatt
    19561 tgaacaagtt gggtggacct gttgctatct ttaaggcaag tagtgatgct gctaaaaatg
    19621 gaattgaaaa tatcttgtac ttcttggcaa tgatttccat caatattggg atttttaatc
    19681 ttattccgat tccagccttg gatggtggta agattgtgct caatatccta gaagccatcc
    19741 gccgcaaacc attgaaacaa gaaattgaaa cctatgtcac cttggccgga gtggtcatca
    19801 tggttgtctt gatgattgct gtgacttgga atgacattat gcgactcttt tttagataat
    19861 cgaggaatat tatgaaacaa agtaaaatgc ctatcccaac gcttcgcgaa atgccaagcg
    19921 atgctcaagt tatcagccat gctcttatgt tgcgtgctgg ttatgttcgc caagtttcag
    19981 caggtgttta ttcttatcta ccacttgcca atcgtgtgat tgaaaaagct aaaaacatca
    20041 tgcgccaaga attcgaaaag attggtgctg ttgagatgtt ggctccagcc cttcttagtg
    20101 cagaattgtg gcgtgaatca ggtcgttacg aaacctatgg tgaagacctt tacaaactaa
    20161 aaaaccgtga aaaatcagac tttatcttag gtccaactca cgaagaaacc tttacagcta
    20221 ttgtccgtga ttctgttaaa tcttacaagc aattgccact caacctttat caaattcagc
    20281 ccaagtatcg tgatgaaaaa cgcccacgta atggacttct tcgtacacgt gagtttatca
    20341 tgaaggatgc ttatagtttc cacgctaact atgatagttt ggatagtgtt tatgatgagt
    20401 acaaagcagc ctatgagcgt attttcactc gtagtggttt agacttcaag gctattattg
    20461 gtgacggtgg agccatgggt ggtaaggata gccaagaatt tatggccatt acatctgctc
    20521 gtacagacct tgaccgctgg gttgtcttgg acaagtcagt tgcctcattt gacgaaattc
    20581 ctgcagaagt gcaagaagaa atcaaggcag aattgctcaa atggatagtc tctggtgaag
    20641 ataccattgc ttactcaagt gagtctagct atgcagctaa cttagaaatg gcaacaaacg
    20701 agtacaaacc aagcaaccgt gttgtcgctg aagaagaagt tactcgtgtt gcaacgccag
    20761 atgttaaatc aattgatgaa gttgcagctt tcctcaatgt tccagaagaa caaacgatta
    20821 aaaccctctt ctacattgca gatggtgagc ttgttgcagc ccttctagtt ggaaatgacc
    20881 aactcaacga agtcaagttg aaaaaccact taggagcaga tttctttgac gttgctagcg
    20941 aagaagaagt ggcgaatgtt gttcaagcag gatttggttc acttggacca gttggtttgc
    21001 cagagaatat taaaattatt gcagatcgta aggtgcaaga tgttcgcaat gcagttgtcg
    21061 gtgctaacga agatggctac cacttgactg gtgtgaaccc aggccgtgat tttactgcag
    21121 aatatgtgga tatccgtgaa gttcgtgagg gtgaaatttc cccagatgga caaggtgtcc
    21181 ttaactttgc gcgtggtatt gagatcggtc atattttcaa actcggaact cgctactcag
    21241 caagcatggg agcagatgtc ttggatgaaa atggtcgtgc tgtgccaatc atcatgggat
    21301 gttacggtat cggtgtcagc cgtcttcttt cagcagtgat ggagcaacac gctcgcctct
    21361 ttgttaacaa aacgccaaaa ggtgaatacc gttacgcttg gggaatcaat ttccctaaag
    21421 aattggcacc atttgatgtg catttgatta ctgtcaatgt caaggatgaa gaagcgcaag
    21481 ccttgacaga aaaacttgaa gcaagcttga tgggagctgg ttatgaagtc ttgacagatg
    21541 accgtaacga acgtgtcggt gttaaattta gcgatagtga cttgattggt cttccaatcc
    21601 gtatcactgt tggtaaaaaa gcggccgatg gcattgtaga agttaagatc aaggcaactg
    21661 gtgacaccat tgaggttcat gcagataacg tgcttgaaac gcttgaaatc ctaagcaaga
    21721 aataaaaact ataatcagaa gaaaaacaag gaaaaaatgt aactagtttt taccttgttt
    21781 tttctgtata atgggagaaa tgagtagata aagaggtaaa tgttatgcta agatttccaa
    21841 aggattttgt ctggggatcc tctacttctg gaccgcagac agaaggacgt gtagctggtg
    21901 acggtaaggg agacaatctc tgggattact ggttccaagt ggagccaaat cgttactata
    21961 atgggattgg ttcagataag acatcgactt tttatgaaaa ttgggagcgg gatattgagc
    22021 ttttgttaga gactggtcac acagtctttc ggacttctat tcagtggtca cggatttttc
    22081 cacaaggctg tggaaaagtc aaccctcaag gtgtggattt ttatcgtaag gtctttgagg
    22141 ctattaaggc taaaggaatt cgtctgttag tcaatctcta tcattttgat ttaccttttg
    22201 cccttcaaga ggatggtgat ggttgggaaa ataaggcgac agtctcagcc tatgaagact
    22261 atgctcgttt ttgttttgag acttatggag atttagtgga tcaatggatt acctttaacg
    22321 agctcatcgt tcctgtagaa tttggttatt tttatgatgc ccattatcca cataaggtgg
    22381 atgcagaggc agctgttaag gtagcctatc atacacaatt ggccagcagc cgggctgtta
    22441 aggcttgcca tgaacttttg cctgattcca agattgggat tgtcctcaac ttgacaccgg
    22501 cttatccacg tagccagcat cctgctgatg tcaaggcagc tcgtattgcg gccctttttc
    22561 aggcccaatc tttcttagat ccatctgtct tggggactta tccacaggag ttggtagaaa
    22621 tcttgcatga acacggtctt ttacctgatg ctacagagga agagttggaa ctcattcatg
    22681 ataatacggt ggacttcctt ggtgtgaact actatcaacc tttgcgtgtt atggctcctc
    22741 gatttgctaa gcatccagag agtccactct taccagaaca tttttacgag ccttatgtga
    22801 tgcctggacg taaaatcaat tctcaccgtg gttgggagat ttatgagcaa gggatttatg
    22861 acatcgccca aaatatcaag gaaaattatg gcaatattga atggatgttg actgagaatg
    22921 gtatgggtgt tgaaggggaa gaaaaattcc gtcaagatgg aatgattcaa gatgattacc
    22981 gtattgactt tgtaaaaggt catcttcgtg aacttcaccg tgccattgaa gatggtgcca
    23041 actgtaaggg ctacttgatt tggaccttta ttgactgctg gtcatggctc aacagctata
    23101 aaaatcgcta tggtttggtc gaattagact tggaaacgca agaacgtcgt ctgaagaaat
    23161 caggccactg gttcaaaaaa ttaagcgata ataatggatt ttaaaaagga ctctgactga
    23221 ttatcccaat cggtcagagt tttttgctta caggagctta atttgaacta taccaatttt
    23281 tactcttgac aagtgaaaga aacaagtata tactgttttt gctgattcta taaaagatga
    23341 attagactat accaatttta aggagaaagc acagcttgcc tgtgtcgtat atactatgtg
    23401 tggaattgtt ggtgttgttg gaaacacaaa tgcaactgat attttgattc aagggcttga
    23461 aaagcttgaa taccgtggct atgattctgc gggaattttt gtcctagatg gtgctgataa
    23521 ccatttggtg aaggctgttg gtcgtatcgc agaattgtct gccaagacag ctggtgttga
    23581 gggaacaact ggtatcggac atactcgttg ggcaactcat gggaaaccaa cggaagacaa
    23641 tgctcaccca caccgctctg agacagaacg ttttgtcttg gttcacaatg gggtgattga
    23701 aaactacctt gaaattaaag aagaatacct tgctgggcac cacttcaaag ggcaaacaga
    23761 tacggaaatc gccgtacatt tgattggaaa atttgcggaa gaagacggtc tctcagttct
    23821 tgaagccttt aaaaaagctc ttcatattat ccgtggttca tatgcctttg ccttgattga
    23881 ctctgaaaat ccagatgtca tctatgtagc gaaaaacaaa tctccacttt tgattggtct
    23941 tggggaaggc tacaatatgg tctgctcaga tgctatggct atgattcgtg aaaccaacca
    24001 atacatggaa attcatgacc aagagttggt aatcgtcaag gctgatagcg tggaagttca
    24061 agactatgat ggaaatcgtc gtgagcgtgc tagctacact gctgaacttg acttgtcaga
    24121 tatcggtaag ggaacttacc cttactacat gctcaaggaa attgacgagc aaccaactgt
    24181 tatgcggaaa ctcatccaag cctacacaga tgaggctggt caagttgtcg tagacccaga
    24241 tatcattaag gctgttcaag acgcagaccg catctacatc cttgcagctg gaacatctta
    24301 ccatgcagga tttgcttcta agaagatgtt ggaagaattg acagatacac cagttgaact
    24361 tggaatctca tctgagtggg gctacggtat gccacttctc agcaagaaac cactcttcat
    24421 ctttatcagc caatctggtg aaacagcgga tagtcgtcaa gttttggtca aggctaatga
    24481 aatgggaatt ccaagcttaa cagtgacaaa tgttccaggt tcaaccctct cacgtgaagc
    24541 caactatacc atgctccttc acgcaggtcc tgaaattgcc gtggcatcaa ctaaagccta
    24601 tacagcgcaa atcgcagccc ttgccttcct tgcaaaagca gtcggagaag caaatggtaa
    24661 tgctaaagcg caagcctttg acctggttca tgaattgtca atcgtagctc agtctattga
    24721 atcaactctt tcagagaaag aaaccattga agccaaggtt cgtgaacttc ttgaaacaac
    24781 tcgtaacgcc ttttacatcg gacgtggtca agattattac gtagccatgg aagcaagtct
    24841 caaactcaaa gagatttctt atatccagtg tgaaggtttt gcggcaggag aactcaagca
    24901 cggaaccatt gccttgattg aagaaggaac gcctgttttg gctctcttgt cagatccagt
    24961 tcttgccaac catactcgtg gaaatatcca agaggtcgca gcccgtggtg ccaaagtcct
    25021 cactatcgca gaagagaatg tagccaaaga taccgacgat atcgtcctta cgaccgtaca
    25081 tccatacctc tcaccaattt caatggtcgt accaacgcaa ttagtcgctt actttgcaac
    25141 cctccaccgt ggcctcgatg tggacaaacc acgtaacctt gccaagtcag taacggtaga
    25201 ataagctaaa aaagtctagt tatctaggct ttttcttgtg agcaaattgg ttgcttgtac
    25261 tcaagattcg tgttatactc ttagaaaatc tcttcaaacc acgtcaccgt cgccttgccg
    25321 taggtatggt tactga
//
LOCUS       DAVAZV010000028        24327 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVAZV010000028 DAVAZV010000000
VERSION     DAVAZV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.028"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..618)
                     /locus_tag="VQT46_001124"
     CDS             complement(<1..618)
                     /locus_tag="VQT46_001124"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET2371161.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEK"
     gene            complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQT46_001125"
     CDS             complement(769..2079)
                     /gene="secY"
                     /locus_tag="VQT46_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET2371162.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQT46_001126"
     CDS             complement(2092..2532)
                     /gene="rplO"
                     /locus_tag="VQT46_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET2371163.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQT46_001127"
     CDS             complement(2677..2901)
                     /gene="rpmD"
                     /locus_tag="VQT46_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET2371164.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQT46_001128"
     CDS             complement(2873..3367)
                     /gene="rpsE"
                     /locus_tag="VQT46_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET2371165.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQT46_001129"
     CDS             complement(3385..3741)
                     /gene="rplR"
                     /locus_tag="VQT46_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET2371166.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQT46_001130"
     CDS             complement(3825..4361)
                     /gene="rplF"
                     /locus_tag="VQT46_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET2371167.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQT46_001131"
     CDS             complement(4553..4951)
                     /gene="rpsH"
                     /locus_tag="VQT46_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET2371168.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQT46_001132"
     CDS             complement(5236..5505)
                     /gene="rpsN"
                     /locus_tag="VQT46_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET2371169.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQT46_001133"
     CDS             complement(5523..6065)
                     /gene="rplE"
                     /locus_tag="VQT46_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET2371170.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQT46_001134"
     CDS             complement(6089..6394)
                     /gene="rplX"
                     /locus_tag="VQT46_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET2371171.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQT46_001135"
     CDS             complement(6472..6840)
                     /gene="rplN"
                     /locus_tag="VQT46_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET2371172.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQT46_001136"
     CDS             complement(6866..7126)
                     /gene="rpsQ"
                     /locus_tag="VQT46_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET2371173.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(7151..7357)
                     /locus_tag="VQT46_001137"
     CDS             complement(7151..7357)
                     /locus_tag="VQT46_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET2371174.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQT46_001138"
     CDS             complement(7367..7780)
                     /gene="rplP"
                     /locus_tag="VQT46_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET2371175.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQT46_001139"
     CDS             complement(7784..8437)
                     /gene="rpsC"
                     /locus_tag="VQT46_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET2371176.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQT46_001140"
     CDS             complement(8450..8794)
                     /gene="rplV"
                     /locus_tag="VQT46_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET2371177.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQT46_001141"
     CDS             complement(8806..9087)
                     /gene="rpsS"
                     /locus_tag="VQT46_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET2371178.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQT46_001142"
     CDS             complement(9191..10024)
                     /gene="rplB"
                     /locus_tag="VQT46_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET2371179.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(10042..10338)
                     /locus_tag="VQT46_001143"
     CDS             complement(10042..10338)
                     /locus_tag="VQT46_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET2371180.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQT46_001144"
     CDS             complement(10338..10961)
                     /gene="rplD"
                     /locus_tag="VQT46_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET2371181.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQT46_001145"
     CDS             complement(10986..11612)
                     /gene="rplC"
                     /locus_tag="VQT46_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET2371182.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQT46_001146"
     CDS             complement(11828..12136)
                     /gene="rpsJ"
                     /locus_tag="VQT46_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET2371183.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(12402..13019)
                     /locus_tag="VQT46_001147"
     CDS             complement(12402..13019)
                     /locus_tag="VQT46_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET2371184.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQT46_001148"
     CDS             complement(13016..13606)
                     /gene="nrdG"
                     /locus_tag="VQT46_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET2371185.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKEIYEQVKRE"
     gene            complement(13599..14105)
                     /locus_tag="VQT46_001149"
     CDS             complement(13599..14105)
                     /locus_tag="VQT46_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371186.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKSQSAHDGGFWDVEDFSYEEWL
                     EGNRNKEMGIWLPENRVPSIQFVLFGESGCALGFLNLRLRLNEGLLNYAGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(14149..14289)
                     /locus_tag="VQT46_001150"
     CDS             complement(14149..14289)
                     /locus_tag="VQT46_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371187.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQT46_001151"
     CDS             complement(14301..16508)
                     /gene="nrdD"
                     /locus_tag="VQT46_001151"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET2371188.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNCRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            complement(16628..18166)
                     /locus_tag="VQT46_001152"
     CDS             complement(16628..18166)
                     /locus_tag="VQT46_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2371189.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            complement(18203..18346)
                     /locus_tag="VQT46_001153"
     CDS             complement(18203..18346)
                     /locus_tag="VQT46_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371190.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQT46_001154"
     CDS             complement(18424..19956)
                     /gene="cls"
                     /locus_tag="VQT46_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET2371191.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            complement(20102..20659)
                     /locus_tag="VQT46_001155"
     CDS             complement(20102..20659)
                     /locus_tag="VQT46_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET2371192.1"
                     /translation="MTPLFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQQVQQPAQQPAQQNTNTANAGGNQNQAAPVQNQPVAQP
                     TDIDGTYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKI
                     YTVNGNQIVVDDMDRDPSDQIVLTK"
     gene            complement(20656..21906)
                     /locus_tag="VQT46_001156"
     CDS             complement(20656..21906)
                     /locus_tag="VQT46_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET2371193.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRIQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFEMLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVNLYQA
                     GQDFLMLNGDFSSSLLNFSQLNIGLEGVYQQENAALALQTFLLFMGEGKEAVDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGALKRKD
                     YQGMLGYLTEKLPQVELKVTGFDYQGALDERDVTGYDIVSSCREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            complement(22114..22419)
                     /locus_tag="VQT46_001157"
     CDS             complement(22114..22419)
                     /locus_tag="VQT46_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET2371194.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQT46_001158"
     CDS             complement(22435..22854)
                     /gene="ruvX"
                     /locus_tag="VQT46_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET2371195.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPLDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            complement(22858..23124)
                     /locus_tag="VQT46_001159"
     CDS             complement(22858..23124)
                     /locus_tag="VQT46_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET2371196.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            complement(23211..23780)
                     /locus_tag="VQT46_001160"
     CDS             complement(23211..23780)
                     /locus_tag="VQT46_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2371197.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQT46_001161"
     CDS             complement(23846..24244)
                     /gene="spx"
                     /locus_tag="VQT46_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET2371198.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
BASE COUNT         6740 a         5398 c         4560 g         7629 t
ORIGIN      
        1 tttttcaata tctgagaaga catcattgat atcttgatta ccttcgatgt catgaaccaa
       61 acctttggca cggtagtgag caatgattgg ttctccttga gcaatattaa catccaaacg
      121 acgttttact gtctcaggct tatcatcttc acgttggtag taatcttctt ctttatagtc
      181 aactggtggg ttaaagacct tgtggaaagt ttctccagtt acgcggtgga tgatacggcc
      241 actcaaacgt tccaagaggc tgtcagggtt cacttcaata ttgataatac cttctagttc
      301 aatgccaagt tcagccaatg ttttgtccaa ggcatgagct tgttcaattg tacgtgggta
      361 accatccaat aagaatcctg tttctttaat atcatcttgt gaaaggcgtt cttttacgat
      421 tccatttgta acttcgtcag gaaccaattc acccttgtca atatatgact tagcaagaac
      481 acccatttca gtttgatttg ccattgcagc gcggaacata tcacctgttg agatatgtgc
      541 aacatggaat tgttctacga tttttgctgc ttgagttccc ttacctgcac caggtaagcc
      601 cataatcaaa agattcatga tttgatctcc ttattttatt tttaaataga agcaaaaagt
      661 cttttcaccc ctatttaaaa acaaaataga agaggggaga tccaactctt acaaatgtca
      721 gagtttaaac ctccactccc tcagtattta ctgattcagt aaatactttt attctgttct
      781 gtccatgaaa ccaacatact tacgtttcaa taggtaacct tccaattgct tgattccttc
      841 gatacctgta gagataatga tcaagagact tgttccacca aaggcaacaa catcagaaag
      901 accaaataca tctttagctg caatcggtaa aatggaaatc acaccaagga agagggaacc
      961 aacagttgca agacgacgaa gaagtttaga catatattct tctgtacctt taccaggacg
     1021 aactccatgg atataggcac cactcttttg taggctctct gctgcttttt caggattaat
     1081 ctgtacaaac gtatagaaga atgtaaagag aataatcaac aaagcataca tggcaatacc
     1141 agttggagaa gtagttgcca acatctcttg tgctaccctt acccaagccc aatcatgacc
     1201 tgtggcactc aaaaactgaa gaatagccgc aggcgctgca gtaatcgaac tggcaaagat
     1261 aacagggata actccagcag ggtttacctt taacggaagg taagagctag atggagcacc
     1321 ttgtgcaacc ttagtatatt ggattggaat tttgtattct gcttgttgaa cataagttgt
     1381 aaagtaaata atcaacaata cagtaataat caaaatgatt acgaaaatga tagatgaagt
     1441 gatacggcta cttgggacgt tcacaaagta gtccacatag atgccctgaa tcatctctgg
     1501 aattgaggaa acaatcccgg caaagataat catggaaaca ccgtttccgt atcccttatc
     1561 tgtaatttgc tcacccaacc aagtgacaat catactacca gctgttaaga tgataccaat
     1621 cgtcagaaaa acttgtggag ttaaagcagt tttaatcaat tgagctccag ccaaggtatt
     1681 aaaaccagct gtaatcccga tagattgcac aaaagcgaga actagagcaa tataacgagt
     1741 agcttgattc aattttcttc gacctacttc cccttgttta ccccactcta caaacttggg
     1801 taaaatatcc atttgcaaga gttggacaac aatagaagcg gtgatatagg gactaactcc
     1861 tagggcaaaa atcgaaaagt tttttagggc attccccgac accaagctca acatgtttaa
     1921 gaaggataat ccacttaaag cattcaagct attggcattc acaccaggaa ctgtaatgct
     1981 agttccgata cgaaagacca aaacgataaa aattgtaaat aaaatttttg atcgaacctg
     2041 cttgacttta agagcttctc ttaataattt aaaaaacata ggtcacctct cttagatgac
     2101 ttctactgaa ccacctttag cagtgatagc ttcttcagct gatttagaga atttagctgc
     2161 tttcacagtc aatttcttag tcaactcacc gttaccaaga attttaatac ctgacttttc
     2221 agctttaaca attcctgctt cgataagaac aactggagtt acttcagcac catcttcaaa
     2281 gacgttcaat tggtcaaggt tcacaattgc gtattcttta gcgttgatgt tagtgaatcc
     2341 acgttttgga agacgacgga acaatggagt ttgtccacct tcaaaaccaa ggcgaactcc
     2401 gccaccgcta cgagcttttt gacctttttg accacgacca gatgttttac cgttacctga
     2461 tgaagtacca cgaccaacgc ggttacgtac tttacgagaa ccttctgcag gtttcaattc
     2521 atgaagtttc atttttattt tctcctcttt tgtaaaatgc tagcgccgat aagggagaaa
     2581 aggttgtctc ccccatcaac tcgcctatac gatgtcatca tagatgacta tatctagttt
     2641 taggggatgg tacagtgcac atcccctaaa acttcattag tttacttctt caactgttac
     2701 taagtgagat actgctgtaa tcataccacg gatagcagcg ttatcttctt taataacaga
     2761 gctgttcaat ttgccaagtc caagtgctac aacagtttta cgttgtgatg gaatgcgtcc
     2821 gattggagac ttagtcaaag taattttaat ttgagccatt ttatcccctt tcttatgcca
     2881 aatcagaaac tgaaatacca cgaagggcag caatttcttc agcgcgtttc aattgtttca
     2941 aaccttcaac agttgcacga acaatgttga ttggagtgtt agaaccaagt gatttagatg
     3001 taatatctgc cacacctgcc aattccacaa cggcacgaac tgcaccacca gcggcaactc
     3061 cagaaccttc tacagcaggt ttcaacaata ctttagctcc accgaattct gaaagaactt
     3121 cgtgtgggat tgttgttcca accataggaa cttcgatcaa gtttttctta gcatcatcta
     3181 ctgctttacg gattgcttct ggaacttctt gagctttacc agtaccaaat cctacgcgac
     3241 cattgtggtc accaacaaca acaagagctg cgaaacgaag acgacgtcca cctttaacaa
     3301 cttttgtaac acggttgaca gcaactacgc gttcttctaa ttcaactgca ttgtctttaa
     3361 atgccatttt ctagtgtcct cctattagaa tttcaatccg ttttcacgag ctgcatcagc
     3421 caaagctttc acacgtccgt gatatagata tccaccgcgg tcgaacacca cttctgaaat
     3481 acctttagcg tttgcacgtt ctgcaacgag tttaccgaca gcaacggctt gttcagtttt
     3541 agttcctttt gaaacttctt tatcaagagt tgaagcactt gcgagcgtta cacccgctac
     3601 gtcatcaatc acttgagcgt agatgcctgt attagaacgg aatacgttca aacgtgggcg
     3661 atcagcagtt ccagagagtt ttccgcgaac gcgacggtgg cgtttttggc ggagtttgtt
     3721 tttatctggt tttgaaatca cagttttcac ctctttagtt ttaaatcgtg tgctatgcac
     3781 aaagttggaa aataggttgg tggttgatga tcaaccactc aacattattt acctgtttta
     3841 ccttctttac ggcgaacgaa ttcaccaacg taacggatac ctttaccttt atatggttct
     3901 ggtgaacgaa ggctacgtac gtaagcagct gtttgaccaa ctacttcttt tgaaattccg
     3961 ctaacaacga ttgttgttgg gtttggaagt tcaaaagtaa ttccttctgg agcttcaact
     4021 tcgtctggat gagatttacc aacagccaaa acaagtttag atccttgaag ctgtgcacgg
     4081 taaccaaccc cacgcatttc aagttctttc ttgaatcctt ctgatacacc aacaaccatg
     4141 ttgttcaaaa gggcacgagt agttccgtgg atagttttca tttcttttga atcgtttgga
     4201 cggtgaagag ttatttcagt accttccaca cggatttcaa tatcttttga gaactcacga
     4261 gtaagttctc ctttaggtcc ttttacagtt acaacgttgt cattgttagc gagttcaaca
     4321 ccagcaggca acacgataac tttattacca atacgtgaca tgtttatttt ctcctgttaa
     4381 attgtcaggc cagaacggcc agttttcacg gggttcagat acttatttag ttcaagagct
     4441 gaactgaaca cgctctaaga actgtgcaaa atagataagt tggcttgttt gtaaacaaac
     4501 ttctccaact tcctaatttt gctttgttct ttacgagctt tgtatcttga ttttaccaaa
     4561 cgtaagcgat aacctcacca ccaacattct tttggcgtgc ttctttatca gtaagcaaac
     4621 cttcagaagt tgaaaggatg gcaattccaa gtccgttaag aacttttgga aggtcttcac
     4681 gttttttgta gacacgaagt cctggtttag aaacacgttt caagttagtg ataactttct
     4741 caccatttgg tccgtattta agaaatacac ggatgacgcc ttgtttgtca tcttcaatga
     4801 tttcaacgtt ttttacaaaa ccttcgcgtt taaggatttc agcaatccct tttttgatgt
     4861 ttgatgcagg tacttcaagt acttcgtgtt tagcttggtt agcattacga atacgagtta
     4921 ggaagtctgc gattgggtca gtcataacca ttttgttttt ctcctcttac tagtagtttg
     4981 caagttgcac ttgctagtta atacatgata caaagagcgt aacagcacga gcaaaaatag
     5041 acaatttaat gcagaagcaa tgctccaaag caaattggtc ttttttgcca aagctgtagc
     5101 tcgtgttcaa attggcaagc ccaattgaac ccgggctaaa ctctgtgtga aaaagataaa
     5161 ctttcctaga aactttagtt tcttcgtcaa gtttcctatt tttacttgga gttttgacgc
     5221 tcttgatatc ttaaattacc aagatgcttt tgttacacca ggaatttgac ctttatgcgc
     5281 aagttcgcga aaagcgatac gactcagacc aaatttgcgg taaactgaat gtgggcgccc
     5341 cgtaactcta caacgattat gtaaacgagt cggtgaggcg ttgcgaggta atttagataa
     5401 accttcgtag tcccctgccg cctttaatgc agcacgtttt tcagcataac ggtcaacaat
     5461 tttttggcgt ttagcctctc tagctaccat tgatttttta gccattagat ttacctccta
     5521 tattattttg caaaaggcat tccaaggcct gtaagcaatg cacgtgactc ttcgtcagtg
     5581 ttagcagttg ttacgataac gatgtcaaga ccacgagttt tgtcaacgtc atcgaagttg
     5641 atttctggga agattaattg ttctttcaca ccaagtgtgt agttcccgcg tccatcaaat
     5701 gattttgttg gaacaccgtg gaagtcacgt acacgtggaa gtgaaactga taccaattta
     5761 tccaagaatt cgtacatacg ttcaccacga agggtaactt ttgcaccgat cgcaacacct
     5821 tcacgaagac ggaagccggc gattgatttt ttagctttag tgataagtgg tttttgacct
     5881 gagataagtg ccaattcttc agcagctttt tcaaggcttt tagcgtttga tacagcttca
     5941 ccaacaccca tgttcaaaac aatcttatct actttaggca cagccatcac tgatgagtag
     6001 ttgaattgtt ctgtcaaagc aggaactact tcattaagat atttttcttt taaacgattt
     6061 gccattatac ttctcctttc cttcgtgatt aatcaagcac ttcgcctgat tttttgttgt
     6121 agcgaacttt tttaccgtct acaaatttgt aaccaacacg accagctaca ccatttttgt
     6181 ccaaaacttg aacgtttgat acgtggatag ctgcttcttt ctcgatgata ccaccttgag
     6241 gaagctcgtt agttggacgt tggtgtttct taacaatgtt aacaccttca acgataactt
     6301 tgtttacttt tggaagggca gtaaggacaa cagcttctgt tcccttatct ttaccagcga
     6361 ttacgcgaac tttgtcgcct ttttttacaa acattaggtt tctccttgat ttttcttacg
     6421 cccataaggg caccctagct tgaagctagg ggactagttt gttcctaaaa attaaagtac
     6481 ttctggagca agtgacacga tcttcatgaa gccaccttca cgcaattcac gtgcaactgg
     6541 gccaaagata cgtgttccgc gaggagtttt gtcttcacgg atgataactg ctgcgttttc
     6601 gtcaaatttg atgtatgaac catcagcacg acgagcacct gatttagtac gaacgataac
     6661 tgctttaaca acgtcacctt ttttaaccgc accaccagga gtagcttgtt ttacagatgc
     6721 cacgataaca tcaccgatgt ttgcaaattt acgtcctgaa ccaccaagaa ctttgatagt
     6781 caagatttcg cgagcaccgc tgttgtctgc gactttcaaa cgagtttctg tttgaatcat
     6841 ttcagttttc tcctttcagg tttgattaga tgatgaccgc ttcttcaaca acttctacaa
     6901 gacggaaacg ttttgtagct gaaagcgggc gagtttccat gatacgtacg atatcgcctt
     6961 ctttggcaac attgttttca tcatgagctt tgtatttttt agagtagtta atacgtttac
     7021 catagactgg gtggttacgt tttgtttcaa ctacaactgt gattgtcttg tccattttgt
     7081 cagatacaac acgtccaaca agaactttac gattattgcg ttccattgaa atttctcctt
     7141 ccctagtcta ttatttcgct tcagattgaa ctgttttgat acgagcgatt tgttttttaa
     7201 cttctttcaa gcgagctgtt tgttccaatt gaccagtagc agcttggaaa cgaagttcaa
     7261 acaattcttt tttcaattcg ttttcgcgct tcgcgagttc ttcttgagaa agaccacgaa
     7321 gttctttaac aaattctttt acttcattaa gtttcatgcc ttctccttat tctgcttcac
     7381 gttttacgaa tttacattta actggcaatt tgtggctagc aagtcgaagc gcttcacgtg
     7441 caatctcttc agatacacca gcgatttcga acatcacttt accacgttta actggtgcta
     7501 cccaaccttc aggtgcccct ttaccagatc ccatacgcac accgatagct ttagcagtgt
     7561 atgatttgtg tgggaagatt ttaatccaaa ctttaccacc acgtttcatg taacgagtca
     7621 tggcgatacg agcagcttcg atttggcggt tagtgatcca gtggctagtt gtagcttgaa
     7681 gaccgtattc accgaatgct acttcttttc caccttttgc ttcaccgcgc atttttccac
     7741 ggaactcacg acggtgttta acacgtttag gtactaacat tggttattta cctcctttag
     7801 tgtttttacg agctggaaga acttcaccac ggtagatcca tactttaaca ccaagtttac
     7861 cgtatgtagt atctgcttct tcccaagcgt aatcgatatc tgcacgaagt gtgtgaagcg
     7921 gaacagttcc ttcagagtat ccttcagcac gggcgatatc tgcaccgttc aaacgacctg
     7981 atacttgagt tttgattcct ttagctccag cacgcattgc acgttggatt gcttgttttt
     8041 gtgcacgacg gaaagcaaca cgttgctcca attgacgagc aattccttca cctacaaggt
     8101 gagcatccaa atcaggttgt ttgatttcga tgatgttgat gtgtacttgt tttccagtca
     8161 atttgttaag ttttgcacgg agtgcatcaa cgttagcacc acctttaccg ataaccatac
     8221 ctggtttagc agtgtgaagt gaaacgttaa ctttgtttac tgcgcgttcg atttcaatag
     8281 ttgaaactgc tgcgtcagca agttcttttt gaacgaattt acggattgca agatcttcat
     8341 gaaggtaatc cgcgtattct ttttcagcat accatttggc atcccaatca cggatgatgc
     8401 cgacacgcat accaattgga tgtacttttt gacccacgat tttacctcct tatttttctg
     8461 caacagctac agtgatgtga gctgtacgtt tgttgattgg tgaagctgaa cctttcgcac
     8521 gtggacggaa acgtttcata gttggtcctt cgtttgcgaa tgcttcagat actaccaaat
     8581 tagctttatc caaaccaaag ttgttttcag cgttagctac agctgagttc aaaactttca
     8641 agatgatttc agcagctttg tttggagtga atgtcaagat tgcgattgca tcggctacgc
     8701 ttttaccacg gatgttatca agaacaagac gtgatttacg aggtgaaaca cgtactgtac
     8761 gagccattgc tttagctgaa gtaatttctg ccatttatgt tctccttatt ttctacgtgt
     8821 tttcttgtcg tctgcagcgt gacctttgta agtacgagtt ggtgcaaatt caccaagttt
     8881 gtggcctacc atgtcttctt ggatgtaaac aggtacgtgt ttacgtccgt cataaactgc
     8941 aatagtgtaa ccaatgaaac ttgggaagat cgttgaacga cgtgaccaag ttttaataac
     9001 ttttttcttt tcgtcgttag cttgagcttc aacttttttc atcaaatgct catcgacgaa
     9061 aggtcctttt ttaagactgc gtcccatttt tatattttct cctttaaatg ttgtaccaca
     9121 gcggcttgca ctcctatgga gcgctaccga gctggcggat ttactagttg cttaagcgac
     9181 tagtttaata ttatttctcg ttgcgacgac gaacgataag tttgtcagat ttcgctttct
     9241 tgttacgagt tttaagacca agagcaggtt tgccccatgg agtagatggt gctttacgac
     9301 caactggtgc tttaccttca ccaccaccgt gtgggtgatc gttagggttc attacagaac
     9361 cacgaactgt tgggcggata cctttccaac ggctacgtcc tgctttacca aggtttacaa
     9421 gtccatgttg ttcgtttccg acaacaccaa ctgtagcacg gcaagttcca agaatcatac
     9481 gaacttcacc tgattgaaga cgaacaagaa catatttacc ttcagaaccc aatacttgag
     9541 cagatgcacc agcagcacgt accaattcac caccacgacc tggtttcaac tcgatgttgt
     9601 gaatcaaagt accaactggg atgttagcaa gtggaagagc gtttccgact ttgatatctg
     9661 cttctggacc tgaaacgata cgttgaccta cttcaagacc ttttggagcg atgatgtatg
     9721 ctttcacacc gtcagtgtag tgtacaagag cgatgtttgc agaacggttt ggatcgtact
     9781 cgattgtttt aacaactgct tcaacgttgt ctttattacg tttgaagtca accaaacggt
     9841 aaaaacgttt gtgtccacca ccttggtgac gaactgtgat acgaccgttg ttgttacgac
     9901 cagccttgct cttcaatgca acaagcaatg atttttcagg agtgcttgtt gtgatttcag
     9961 cgaaatccaa agaagtcata ttacggcgac cgtttgttgt tggtttataa acacgaattc
    10021 ccacgatatt tcctccttag attattcagc ttcagcagca aacaactcga ttgctttaga
    10081 atcagctgta agtgtgatga tagctttttt agttttgtta gtaaaaccag tgtaacgtcc
    10141 aacacgttta gcttttggtt ttacgttgat tgtgttaaca ttggcaactt taacaccttc
    10201 gaaagcagct tcaacagctt gcttgatcaa aagtttgtgt gcacgagtgt caacttcaaa
    10261 tacatatttt cctgcttcaa gttgagccat tgagctttca gtgatgacag gttttttgat
    10321 aacatcatac aaattcatta tgcaagaacc tcctcgattt tagagatagc tgcttgtgtg
    10381 acaagaagtt tgtcgctatt tgcgatgtca agaacacttg cagttgtagc agttgcaact
    10441 ttcacgtttg gaaggttacg agctgaaaga gctgcgaatt catttccttc ttcaaggata
    10501 acaagaactt tagaatcgat gctcaatgct gcaagaactt ttgcaaattc agcagttttt
    10561 ggagctgtaa atgaaagagc gtctacagct acgaatttgt tttcagcaac tttttcagag
    10621 taaactgatt taagagctag gcgacgaact ttttgtggaa gtttgtagcc gtatgaacgt
    10681 ggagttggtc cgaagacaac accaccacca cgccattgtg gtgagcggat agaaccttga
    10741 cgagcacgtc cagttccttt ttgacgccat ggtttgcgtc caccacctga tactgcagag
    10801 cggtttttaa cagcgtgtgt tccttgacga aggcttgcgc gttggctgat gattacatca
    10861 aacacaactg attcatttgg ttcgatacca aatactgcat cgctaagaac aacttggcca
    10921 gcttctttac cagtttggtc aaataatgtt acgtttgcca ttgtgactga tttccccttt
    10981 ctttattatt taccagcttt aactgctgat ttgatagtga taagagattt cttagcacct
    11041 ggtacgttac ctttgataag gataacgttc ttttctggaa caacttgtac aacttcaagg
    11101 ttttgaattg ttacgcggtc gccacccata cgccctgcaa ggtttttacc tttgaatacg
    11161 cggttaggtg caacaggtcc catagaacct ggacgacggt ggtaacgaga accgtgagcc
    11221 attggtccac gtgattgtcc gtggcgtttg ataacacctt ggaaaccttt acctttagaa
    11281 gtaccagtta cgtcaacaac gtctccagct gcgaatgttt caactgtaat ttcagcacca
    11341 acttccaagc cttcaacgtt tttgaattca cgaatgaagc gcttaggagc cgtgttagct
    11401 ttcgctacat gtcctttagc aggtttgttg ctcaatactt cgcgtttgtc atcgaaacca
    11461 acttggatag cgttgtatcc gtctgtttca acagttttaa cttgaagaac aacgtttgga
    11521 gttgcttcaa taactgttac agggatcaat tcgccagctt cagtgaagat ttgagtcatt
    11581 cccacttttt tccctaagat tccttttgtc atgagaaaat agttcctttt ctatattttt
    11641 attcaaaaag tttttaacga gcgtttttta tgctcaagtc taagatacaa agggcgtcaa
    11701 actcaacgtg aaaataggaa actgacacag tgtctagcag acgcgaggaa gtttatcttt
    11761 ttcacaccga gtttagcccg tgttcaatta gattgaaaca ccagcctctg ctcttttata
    11821 ttttagatta aagtttgatt tctacgttta caccacttgg aagatccaat ttcatcaagg
    11881 catcaactgt tttttgagtt gggttaacga tatcgatcaa acgtttgtgt gtacgcattt
    11941 caaattgttc gcgagagtct ttgtatttgt gagtcgcacg aatgattgtg tagaggctac
    12001 gttcagttgg aagtgggatt ggacccgcaa cttgtgcacc tgtacgagta gctgattcta
    12061 cgatttttgc agccgctgtg tcaagcgtac ggtgttcgta agctttcaaa cggatacgga
    12121 tttttttgtt tgccatcttt ttctcctttt cgtctattta agataatagg ctagctccac
    12181 aagaaaaccg acgcggtgtt gcgtggcaat gcaaccgagc gtgtcgcaac ctcttgcatc
    12241 aaaactaagg ctgtaattta cagcaccata atagaataac acaaatcccc tgcgattgca
    12301 agggatttgt taggtttttt cgttttttgg ggatgaaact gttttcctac tttttctttc
    12361 taaaattagg gattttcttc tatatttctt ctatacataa gttaagtcct cttgacatca
    12421 aatttatctt ctgattggtc cactaagata tccgccttag actcagtttc tttatagtat
    12481 cgcagatact gctcccgtct catctgatgg ctagccaata taaaggatgc atcgcgattt
    12541 ctcacagtcg tatctctagc aaggcgtcgc tttaattcgg tctcctcatc cgtgtagaaa
    12601 cagatggttt tttcaaagag ttccttgggt agaaagccaa cagacatccc ttcgacaatc
    12661 aaaattggtt tggctccaga caagacctca ctagccttcc aaggttcttc aattgtcaag
    12721 acatccatac ccgcctgcaa ggcaaggata tctctctgca aactctccag ttcatgcgcc
    12781 actggcagac tggctgtcac cttttgattc ggcgcgtcct tgggtactac caaatagcgt
    12841 ccggaggtga tatagggatc tgtttctagc aaatttactg tagtagaatc taaagcttgg
    12901 tacaattcct gtgcaaaggt tgatttacct gaagctccat gaccgtatat tcccagtgtc
    12961 ctgactttcc ccgtctcgat ctctgagact agttggtcta ctaagtcttt tttcttcatt
    13021 ctctcttcac ctgttcatag atttcttttc cgtcattgag cttgtcccaa atcactactt
    13081 gcccactttt gagcgatttt tgcacatcga taattcgttg gttagacgaa cctcgaaact
    13141 ggagcataag atttctctta gttcgatcat atcttccatc gacaagaatg tcaatcagtg
    13201 acaagagttc cagtttatct ggagtttcca acatcatttc ttcccaagtg tagcccgtcc
    13261 aggaccagat gtccttgtct ggcaattcct tccgaatccg cttaacaagt ggcaagagaa
    13321 tcccagtatt aagaaaaggc tcccctccta gtaaggttaa cccctgaaca taaggctggg
    13381 caagatctgc cataatctgt tcttccaact cagctgtata gggaatgcct gcattgaagg
    13441 accaggtcgc tacattataa cacccctcgc agtgaaacat acagcctgct acatagagag
    13501 agttacgcac gccttcgcca tcaacaaagt taaaggcctt gtagtcaatg atacgacctt
    13561 gactaagttc ctcgcttttc cattcttgtg gttttggatt attcattcgc tacctctatc
    13621 caataacgct cgactccatt gcgagcatcc tcaaatattc caccatttgc tagaatgact
    13681 gctctgctag caggattatt cacgctacag gtcaccagag ctttcttgat gttcttttcc
    13741 ttagcaactt gcaagccctg acggagagtc tcttttgcat aacccttgcc tctttcagat
    13801 ggacggatgg agtagccaat gtggccagca taattcagta acccctcatt cagtctcaat
    13861 cgcagattca aaaatcctag agcacaacct gattcaccaa acaatacgaa ctgtatcgat
    13921 ggaacgcgat tttcaggtag ccatattccc atttctttat tacggttacc ttctagccac
    13981 tcctcgtaag aaaaatcctc aacatcccaa aatcctccat catgggctga ttggctcttt
    14041 tcaaactctg tcatcatatc taaaacagct ttcttatccg ctaatcttgg tctgcgtaat
    14101 tccatcctta cctcccacta tgagaaaagc gagagctggc tctcactttt attttttctt
    14161 gttcttgttt aaaaattgtt ctctgaagct aagcaagcgt tctttcttac cagctccacc
    14221 tttagagtgt ttctcgtgat aacgggtcac ttgtgcgcgc cccttatcgt ctagttgata
    14281 ttttcccatt tcatttcttt ctaatttgtt acttgatgcc cagctatttt aatcgttgaa
    14341 ccattcatat gtttgacacg cgcagcgatt tccttgtgac gcccgttgac catcggtctt
    14401 gcttgaggat tacctaggta gccacaagtt cgcttcacca catctactgt tttagggtcg
    14461 ctattgccac agtttggaca agcaaaccct ctctcagttg gttcaaaatc cccttcaaag
    14521 tcacacttgt agcaacggtc aatcggagta ttggtgccta gatagcctac acggtcataa
    14581 gcataatccc agacagcttc caaggccttt ggattttgct gaaggactgg atactcacaa
    14641 taatggatga aaccacctga cgcacctgct tctggataga ctttctcaaa gtccaatttt
    14701 tcaaacggtg ttggattttt acgaacatcg tagtggaaag agttggtgta gtattccttg
    14761 tctgtgatat caggaataga gccaaacttg tctatatcta gtcggcagaa acggtctgtc
    14821 agactttcgg atggtgttga gtagatagag aaatggtagc catattggtc tgaccactct
    14881 tctacacggc gtttcatatc gtgaatgatg tctagcgtga attccttagc atctggatta
    14941 ctttcccagc tgttaccaaa gaaaactgtc gctacttcat acaagccgat atagcccagc
    15001 gaaacggtcg cacgacaatt cttaaagagc tggtcaacac tttcttcttt acctagacga
    15061 tggccaaaag caccgtactg ataaaggata ggagcattcg ctggtgtcgc ctctttagtg
    15121 cgttcgacac ggtaaacaag agcatcttct gcgatattca ttcgctcgtt gaagatttcc
    15181 cagaacttat tcatatcacc ttcagactca agagcaatac gaggcagatt aaccgtcaca
    15241 acacccagat tcatgcgacc tgaattgact tctacaccat tttcatcctt ccatccttgg
    15301 aggaaagaac ggcaacccat aggcaccttg aaggatcctg tcaagtcaac aatcttatcg
    15361 taagataaaa catctggata catccgtttg gttgcacact caagagccaa ctgcttgatg
    15421 tcgtagttgg gagttccttc ctctaaatta aggcctcttt tcagagtgaa aataagttta
    15481 ggaaagatag ccgtacggtg ttctgaacca agacccttga tgcgaatgtt taaaatagct
    15541 ttttgaattt ctcgttcaaa acgactggtt cccagaccaa aacctagcga agtaaaaggt
    15601 gtttgtccat ttgaagtgaa gagagtattg atttcatact caagagattg catggcatcg
    15661 tagatgtcct tttgcgtttt cttccaagcg taatcttccc gtttttcagg caatacccac
    15721 tcttctgcat ctttgagatg tttttgatag ttcttctctg cataaggcgc caaaatttca
    15781 tcgatacggt cagctgaaca gccaccgtac tggctagaag caacgttggc aatgatttga
    15841 gaaatctgtg ctgtcgcagt ctggatagac ttgggactct ctacctctgc atttccaatc
    15901 ttaaaaccat tttccaacat acccttaaaa tcaatcaaac agcagttggt cataggggta
    15961 tagggactgt agtccaaatc gtgatagtgg atatccccct tttggtgggc attggctacg
    16021 tgcttaggaa gcatttgcag tccgattgat ttcccaacaa tccctgctgt caaatcacgc
    16081 tgagtgttaa agacatcact gtctttatta gcattttcat tgacaactgt ctggtctttg
    16141 ttgagaagtt tatgaatact aaagttgata tccgtcgctt ttgagcgctc aaaatccctc
    16201 tgtgtccgat aagtaatata ctcctcagcc agcgcatatt ctttggcttc aaggagttca
    16261 tgttctacga tattttgaat ttcgtaaatc ttaattccct gtggaaagcg actatgaatt
    16321 tctgtaataa ttctctcagt cagatcattg aggcgttttt caaccagggg tgtcacatcc
    16381 ataaccttgt cagctgcctt gtggagagcc ttgtcaatct tgtccacatc aaatacaaca
    16441 cgtctcccat ctcgtttctc gacgaagaga gttggcaaaa ttgtaatttt ttcttctagt
    16501 gcaatcatat gcatgctctt ttctaaaatg ttctttctaa aaagtattat accactctaa
    16561 aaagaaaaat caatatcttg tgttaaaaat cctaaaattt ttaaaaatac acaagatatt
    16621 gatttggtta tttaatttta tagactttaa actctgagta atcagtcttt acttgttggt
    16681 aattttcttt taaaagtgtt tccacttcag accagactac caccttgtca tttaccacaa
    16741 tcaccttagg ttgtttttct ttcaagtcat taagtaactt attacgattt tcctcagttg
    16801 ctgtatagtg caacggggac aaaatcgccg atggcgacaa gcgctcactc ttacgataaa
    16861 gagtcgcagt atcatcccat gcatagatag catcttccgt atttgtctcc tcttttacca
    16921 aatcagcaag acgattacgt tcttgataag gtactggata aaggacaaac ttcatcaaaa
    16981 aaggaacaga caaaagatag acaaacccaa aaactagcag atatagattt cctttgaaga
    17041 aacgactcca taggctaact ggcgtttctc ttcggcttct tctagcacta cgccccctct
    17101 gttgactctt gatattggtt accaataaaa gtaggaaaac agggaagacg accatcaaat
    17161 aagaagcgtg cagaggctct tgtgaaaaga aaagtaaaat caaacctaaa attaccacaa
    17221 gacttgcagg aaccgaaatg acgtatagtt taaagggttt ggattgaaag agacctaaaa
    17281 agatacaaac cacaaatccc aaaccaaggg acaacaagcc ataaaaaaac atattctcta
    17341 aaattttaga agtaaaatca aagcgaatac tgtcaatagg ataacgaata ccactaatcg
    17401 catccccaaa acttcctgtt gcagcactat agtaggcagt tggataaaag acaagtgaaa
    17461 aacctaaagc cactgcaaga aactgataaa acccatgcgc aaagcgtcta tgcccaaggt
    17521 taaagaccaa caagcctaaa ctcactacag caataaacag gagtgatgat aagggagcaa
    17581 agaaaaatcc gcctgccaaa gctaacccaa tccgtacaaa tcccttatca tggcttggat
    17641 tgcttaggta agccgcaact aaactaaagg ctgcgaataa gaaaggaagc gctaaaagag
    17701 tcgcatagcc tccaccaaaa gcaagacctg taactagcat gtaaaaaata gtcaccagat
    17761 gtccagcttg gtctccttgc tctgtcaagg tgtccgctga tctaaaaagg aaaaatcctc
    17821 ctgctaccaa ggctaaccac tcaaagatgg caaagaaaaa tccgccctga ctcacgtaag
    17881 tcagcaaata ataaagcaaa ccttgacttc cataatagtc gctgtaaatc ttccctgtct
    17941 gatgaagcgc ccaacctgca taaaaatcct gcacttcttg tgcactcatt aagtcgagta
    18001 atagcggtac tcctagagtt atccccgtta caagcgtact ccatagtaaa attttcacca
    18061 aaggaagacg acttgattca cgatgatgcg attcttgctc gatttggtat tctagaggtt
    18121 cacgattctc cttatgaact tcttctactc taccatacac actcatatcg tttctcctgt
    18181 tcaatttatc tgtcttagta tatcaaaaag tcctaggatt gtcagcttgc gatggctgtt
    18241 tgagtgattt tttgcatagt ttcacaaagg tttcaatttc ccgaaagcgg tgtaaatgtg
    18301 tctgtttgaa ctcaatcata tcattcactt cttccttagt tagcatgaat tcccctcctc
    18361 tttctttcta ttcgtaaaag acaagaaaaa taggtcgggt ttgtatccta agttctagat
    18421 ttcttataag ataggggcga atagctgggc gatttctttt acaagctttt gataccagct
    18481 cgttttgata gaatgaggat agacttcctg agaatctgca aatatatttc gaaaatctcg
    18541 ggcgatttcc cttatagaag gagttttata gagtaagact gcattttcat aatggtgtac
    18601 caagctccgg tagtcgagat tgattgtccc caccaccgca aaatcttcgt ctaccaacat
    18661 ctgcttacta tgaataaaac ctggactata ctcataaatc cgaacaccag cagaaagaag
    18721 gtcgggataa gctcctctcg tgactaactg aatgaacttc ttatctggta tgtaaggggt
    18781 gataattcga acatcgaccc ctctcatagc tgcatttttg attgtctctg ttaaatcata
    18841 atctataatc aaataaggtg tcgtaatata gaccgattcc gttgcttgat tgattaaact
    18901 ctgataaact tttttcccta cctgcgctcg aaaaattggc ttgggtccac ttccgtatgg
    18961 aatggttaaa ccgtcactcg ggatagaatg attttctaaa tgatattgat caaaatcact
    19021 aatttctcct cgattaatgt accaagtggt caaaaataag cgtgtcaggg cttttactgc
    19081 tagtccgtct aagcgaattc cactatcctt ccaataacca aatctctcga cgtggttaat
    19141 gtactcatct gccagattga ccccaccagt ataggctatc tgaccatcaa caatcaatat
    19201 ttttctatga tctctgttat tataagccac tgtcaaacga ggaataactt tattgaattt
    19261 atgggcctcg atgcccagct gacgaagtcg atgtgcataa tctcctgtta aagtagccat
    19321 acagccgata tcatcataga gcatcttaac ctctacaccc tgagctacct tttgctctag
    19381 tatatctagt atgcgattcc acatcaaacc ttcttctata atgtaatatt ccaagaaaat
    19441 aaatttctca gcctttttaa gatcttctac catctttttc cacatagctt ctccgttagg
    19501 aaaaaatgta gaggcagttt gatcatagat gtcagcattg gtatccatac tcaataagga
    19561 cttgatgact ccataagctg ccttgtcact ttcttttaat ttctctttta gtagctggct
    19621 atttgcttct tggaaatgca tagagcctag cttcttcagt tgtttgattt cttttttgga
    19681 caatcgcctt tcaccaaaca tcagatagag taagggacca aatactggca caaaggctac
    19741 taacaaccag gttaccttat tctcaggagt cgtattacgg ttgactatcg aaatgattgt
    19801 gatgatactc agtagaatga ggacagtaat ccataaaatg ggagccatgc gtcctaaata
    19861 aagaaagaga ccaaaaacaa gacaaagttc aagtagcata atcgaaagac taaagccata
    19921 cttggacatc aataattgaa atttcctata tttcatatcc cctccttgat agtttgaatg
    19981 ctaaaaacaa gtaattgata ctagtataac gcaggtattc ggtagaaggc aagtatttat
    20041 gattattttc taggtaaaag taaaaaggct gaaaaatcca gccctttcta cttgcatagt
    20101 cttatttagt taaaacgatt tggtccgatg ggtctctatc catatcatct acgacgattt
    20161 gattaccgtt tacagtgtaa attttgacat catcgccaat aatcatgcgt tgatttgctg
    20221 aatcaaatgt aacctgtttg actttctgat ccccgtcaga ttcgagctca gtccatgtac
    20281 cagtcgttcc agttaccact aaagtgatac ggtctccgtc atcctgacca gtataagtcc
    20341 catcaatatc ggtcggttga gcaacaggtt ggttttgtac tggagccgct tgattttggt
    20401 tacctcctgc atttgcagta ttggtattct gttgagcagg ttgttgagca ggctgttgga
    20461 cctgctgctg agcaacaggc tgttgaacct gttgagctct ttgtgaacaa gctactaaga
    20521 gactaaaact tgctagagaa gcaagagaaa gtgtgaatct ttttaatttc atgatgaatt
    20581 tcctttctgc taccaattta gagaaatttt ctctaaccag caattcccct agtataacaa
    20641 gttcaaacaa gggggtcaat ttatctgctc acggtccagc aggtagcccc gtacttctga
    20701 gataaaatag agagaccctg taacgaacag caagtcttga gcgtctgccc tttcttcgaa
    20761 actgctgata aattctcggc aagaagaaac tatatcgtaa cctgtcacat ccctttcgtc
    20821 caaagccccc tgatagtcaa agccggtcac cttgagttcc acctgaggca atttttcagt
    20881 caggtaacct aacatccctt gataatcctt ccgtttcaag gctccaaaaa ggatttgagg
    20941 tcgatagcct tcctgctctt tttctttgat aaactcaacc aagcgagtca aggcagggag
    21001 gttatgagca ccatccaagt aaatctgtgg gcgaatacgc tccaagcgac cagcccaatg
    21061 ggtctgttcc aaggcctttc ttacagcctg ttcatcaaca gcttcctttc cttctcccat
    21121 aaaaagaaga aaagtttgca acgccaaggc tgcattctcc tgctgataga ctccttctaa
    21181 gcctatgttc agctgtgaaa aatttagtaa agagcttgaa aaatcaccat tcagcattaa
    21241 aaaatcttga cctgcctgat aaaggttaac agctaaagat tcggcttttt tctgacagac
    21301 aagcctagct tctggaggca atttcgcaat cactgccttc ttaccagcct tgaaaatacc
    21361 agctttctgc tctgcaattg cttctagact atcacccaag gtttcttgat ggtcaagccc
    21421 aatggaggtg atgacagcaa gctctccagt taccacattg gtcgtgtcaa gtaagccacc
    21481 aattcccact tctaataaaa ccaaatccac ctcttgctcc ctaaaataaa gaaaagcaac
    21541 caaggtcagc atttcaaaaa aggacaactg gtcaggagtt tgcagaagcg ttttctccat
    21601 ctccttgacc tgatcagcca aacggataaa gtctgcgtct gctataggtt gcccattaat
    21661 gcagattcgg tcattgatag agacgatatg aggggaggta aaggtcgcaa cttttttgcc
    21721 atgccccata aataattccc tcataaaagc aatggtagat cctttcccat tagtccctgt
    21781 tacgtggata atagggtaag actgctcagg atttcctaac aaatccaccg cttgctgtat
    21841 tcggcccaaa cctgatcgaa aattcaaacc aatccgacta tgaagccatt cttctacttc
    21901 aaacatacac atctccttga caaaagtcca atcaattatc gcattaaagt atggttacta
    21961 ataaaaacaa ggccaggatt ttcgtcccga cctcttacct ggttagctaa taactagcca
    22021 ctatgaatgt gaatatgggc taaaaacatc cactagatgt tccaactctt ccccatttct
    22081 gggagttggg ctgatacagt ctcccagact gtatcactcc tccataaagc tgttgaagac
    22141 ttcttcaatc atgttccatt cgtcttctga gtcttctggg attggttgca attcgccttc
    22201 tgttccatct tcattttcaa tgaatgagta agcttggatt tcaacttgtc cgtcttcgtc
    22261 ttcttctgcg ttaactggta ctagaagaac atagttttta ccaaattctt cttttccatc
    22321 aattgtcaaa aggatttcaa acaaggtttc atttccttgc tcatctacta gtgtgattag
    22381 ttcacgttct tcgtggtcgt ggttatgatc gtgtgacata gcctctcctt tatattaaaa
    22441 ttttctatct aaataatttt gtaaaatcag ctgagctgct aacttatcaa tgactttctt
    22501 gcgcttattg cgactgatat ctgcttgttc aatcaacatg cgctcagcag ccactgttgt
    22561 caagcgttca tcctgatagt ctaatggtaa accaaaaaac tcttctagct ttgctccgta
    22621 ggcttgacta gcttctacgc gcggtccact tgtattgttc atgtttttag gcaagcccac
    22681 tacaaatcgt tccaccttgt aagtatcaac caattcctta acgcggtcaa aaccaaattg
    22741 gccttgttct tcatttatct ggatgatttc aagcccttga gctgtaaaac caagcggatc
    22801 gctaatcgcc acccctaccg tttttgaacc gacgtccaat cccataattc tcataggtta
    22861 tagatcgact ccttgtcctt tgaggtagta gcgaaccaat tcctcaacga tttcatcacg
    22921 ctcatactta cggatttgat ttcgtgcatt attataacga ggaacgtagg cagggtctcc
    22981 actcaatacg taacctacga tttggttaat tgggttgtaa cccttatcgt tcaacgaagc
    23041 ataaacatct gtcaaagttt cgctaatttc ttttttattg gaatcgtcca atttaaaacg
    23101 tactgtttct tcagtaaatc ccattctaac accctctttc cttagaatag taccattata
    23161 gcataattcc ttaccttcta caattcaggc agtctattta tttggatttt ctattgttct
    23221 gtcgcgccat ttgccaatct atctgaaata tatttgcttg gttcattttt caaaagattt
    23281 tccaaaccaa tattcttcag atgttccaac tgggaagcct tcttgacatc cagaacttga
    23341 aaatcaaaac tagtcgttgt ttgaagttcc gttgcgctca atagttttgt ttcaagtttg
    23401 aaacctgcca atttacgagc ttcaatgata gacttatcct tctcctccgc ttcaagaaga
    23461 gctttttgag tttcctccac tccatgttgg tcaatataag tcttcaactc atcagagact
    23521 ggacgttttt gttggatagt tagactcaaa aaagtcttgt ccttgtatgt aatggtttgt
    23581 gtctgctggc taccatcatc tgacttgggc aagaccaaag tcttagttac aactgtattc
    23641 ttctcagcat tttcaataac tggcaatgcc gactgaagcg tatctttttc tgtttttgta
    23701 gctggtccag tttctttttt ctgtccgcaa ccaaccagga caaaaaggaa agctagacta
    23761 acaagaacta tttttttcat ttctttcttc tttctttttg aaattaaaat agaataagac
    23821 tgggaagtgc tcccagcctt gatgtttata gagctgcacg caaacgtgct tctgcatttt
    23881 ctacattacg gacagagcgt ggtaggaagg cacgaatatc gtcttccttg tagccaactt
    23941 gcaggcgttt ttcatctaca aggattgggc tctttaaaat tctcggtgtt tccataatca
    24001 gattgagaac ttcattgaca ctcaaatctt caatatccac tccaagggct ttggcatagc
    24061 gatttttaga cgaaacgatg ctggctattc cgttatctgt tttggttaga atatccagta
    24121 attcttctct cgtaattcct tctttaccaa ggttttgttc tttataactt aactggtggg
    24181 cattgagcca ggtttttgct tttttacagc tagtacaact tgagactgta taaattttaa
    24241 tcatgtacct acccctttcg ctacatgtta ctatcagttt agtctattat accataaaaa
    24301 acatccgact tgcgacctat ttttaat
//
LOCUS       DAVAZV010000029        24166 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVAZV010000029 DAVAZV010000000
VERSION     DAVAZV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24166)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24166)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24166
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.029"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..249
                     /locus_tag="VQT46_001162"
     CDS             <1..249
                     /locus_tag="VQT46_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371199.1"
                     /translation="FLLPTLTTPSAIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSP
                     EYNPIEKTWAHIKKHLKKVLPSCCNTFYEALLSCSCFN"
     gene            complement(456..2714)
                     /locus_tag="VQT46_001163"
     CDS             complement(456..2714)
                     /locus_tag="VQT46_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2371200.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2943..3173)
                     /locus_tag="VQT46_001164"
     CDS             complement(2943..3173)
                     /locus_tag="VQT46_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET2371201.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3363..4046
                     /locus_tag="VQT46_001165"
     CDS             3363..4046
                     /locus_tag="VQT46_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2371202.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSEIVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            4046..4780
                     /locus_tag="VQT46_001166"
     CDS             4046..4780
                     /locus_tag="VQT46_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2371203.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDIAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4934..5791
                     /locus_tag="VQT46_001167"
     CDS             4934..5791
                     /locus_tag="VQT46_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET2371204.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGYRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5933..6805
                     /locus_tag="VQT46_001168"
     CDS             5933..6805
                     /locus_tag="VQT46_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET2371205.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLMTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     GDNAFGEDLVKQVFAGLKQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
     gene            7087..7770
                     /gene="rpiA"
                     /locus_tag="VQT46_001169"
     CDS             7087..7770
                     /gene="rpiA"
                     /locus_tag="VQT46_001169"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET2371206.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7784..8995
                     /locus_tag="VQT46_001170"
     CDS             7784..8995
                     /locus_tag="VQT46_001170"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET2371207.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8997..9539
                     /locus_tag="VQT46_001171"
     CDS             8997..9539
                     /locus_tag="VQT46_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2371208.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYHKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            9555..10364
                     /locus_tag="VQT46_001172"
     CDS             9555..10364
                     /locus_tag="VQT46_001172"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2371209.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10840..11820
                     /locus_tag="VQT46_001173"
                     /pseudo
     CDS             10840..11820
                     /locus_tag="VQT46_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
     gene            11845..12357
                     /locus_tag="VQT46_001174"
     CDS             11845..12357
                     /locus_tag="VQT46_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET2371210.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPISAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            13004..13714
                     /gene="deoD"
                     /locus_tag="VQT46_001175"
     CDS             13004..13714
                     /gene="deoD"
                     /locus_tag="VQT46_001175"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET2371211.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLDDAVCFNEVRN
                     MFGYTGTYKGHCVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13737..14261)
                     /locus_tag="VQT46_001176"
     CDS             complement(13737..14261)
                     /locus_tag="VQT46_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET2371212.1"
                     /translation="MKIAIIGYSGSGKSTIAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(14314..14550)
                     /locus_tag="VQT46_001177"
     CDS             complement(14314..14550)
                     /locus_tag="VQT46_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET2371213.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14618..15538)
                     /locus_tag="VQT46_001178"
     CDS             complement(14618..15538)
                     /locus_tag="VQT46_001178"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET2371214.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWISINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15728..16132
                     /locus_tag="VQT46_001179"
     CDS             15728..16132
                     /locus_tag="VQT46_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371215.1"
                     /translation="MKILKRYILELCFILSFALPFIKGTNADNGRCFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16348..16929
                     /locus_tag="VQT46_001180"
     CDS             16348..16929
                     /locus_tag="VQT46_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2371216.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLDVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16926..18203
                     /locus_tag="VQT46_001181"
     CDS             16926..18203
                     /locus_tag="VQT46_001181"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET2371217.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIRGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            18221..18883
                     /gene="deoC"
                     /locus_tag="VQT46_001182"
     CDS             18221..18883
                     /gene="deoC"
                     /locus_tag="VQT46_001182"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET2371218.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKIVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18870..19259
                     /locus_tag="VQT46_001183"
     CDS             18870..19259
                     /locus_tag="VQT46_001183"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2371219.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMAEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19349..20401
                     /locus_tag="VQT46_001184"
     CDS             19349..20401
                     /locus_tag="VQT46_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET2371220.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALNNAVKDAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20545..22080
                     /locus_tag="VQT46_001185"
     CDS             20545..22080
                     /locus_tag="VQT46_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371221.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            22073..23131
                     /locus_tag="VQT46_001186"
     CDS             22073..23131
                     /locus_tag="VQT46_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371222.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            23134..24090
                     /locus_tag="VQT46_001187"
     CDS             23134..24090
                     /locus_tag="VQT46_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371223.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
BASE COUNT         7022 a         4374 c         5491 g         7279 t
ORIGIN      
        1 tttctcttac caacattaac cacaccatcg gctattatta tggataatgc aagattccat
       61 agaatgggga agctagaact tttatgcgaa gagtttgggc ataaactttt acctcttcct
      121 ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa aaagcacctc
      181 aaaaaggtat taccaagttg ttgcaatacc ttttacgagg ctcttttgtc ctgctcttgt
      241 ttcaattgac tatagcagat tgaaataaga tgagaacaaa tcgattggga aagtaaaatt
      301 aatttctata aatgttttag caattgtttc gtactatttc agattcagtc tactatatat
      361 cataatggac aaagggcaag ctgtcaagaa attacagtta ttttagtaaa aaaagaagca
      421 gaaaaattta attttctact ccttttctat aggatttatt tttctttttc agaactttta
      481 acttcagctt ttttggcaga tttaatctga atgtttccct tgctagtcat aactgctttg
      541 agatcttttt cgcttggatt ttcaaggtag tagtcagtga ttgtgtcctc aatatagtct
      601 tgaatagtcc gacgaagtgg gcgtgctccc atttttggat cataacctag gtcaaccaac
      661 ttttccttga ccttgtcagt tacatccaaa cgaatgttgt tgctagagag gcgcttgtta
      721 acatctgcta gcatgagctc gacaatctga aggaggttat ccttgctgag agccttaaat
      781 tcgataatgc catcaaaacg gttcataaac tctgggctaa agaagttacc gagttcaccg
      841 aggacagaat tggtacgtcc ttctctagca gcaccaaatc caacgctagc ttcggtcttt
      901 cctgtacctg catttgaggt catgataatg atggcatcct tgaagctaac ggtgcgtcct
      961 tgcccgtctg tcaaacgacc atcgtccaag acttgaagaa acatgtgcat aacatctggg
     1021 tgagcttttt ccacttcatc gagaaggatg agagaatatg gattgtggcg aactttttca
     1081 gttaattgac cagcctcatc atagccaaca taacctggag gagcgccgac caacttagcc
     1141 acactatgtt tttccatgta ttcactcata tcaaagcgaa tcatactatc agcagaacca
     1201 aaaagttcga tagccagttg tttggaaagt tctgtcttac cgacaccagt tggcccaacg
     1261 aagaggaagc ttccgattgg gcggttaggg gtaccaagtc cgacacgatt acggcgaata
     1321 gccttggcaa tcttatcgac tgcatcatct tggccaataa catgagactt gagatcttcg
     1381 gctagatgga tgagttgaga ttgttctttc tctttcaaat caccaacagg gatattggtt
     1441 ttctgctcga taatgtgctc aatagttttc tcgctgatga taggagtatc ctggtctgtg
     1501 atctttttct tttgcatttc cttatacttg gcaatctggt cgcggaagta ggccgccttc
     1561 tcaaaatctt cttctcgtgt agcttgagac ttgagatttt cagcctcaat caagcgctga
     1621 tcaattactt taggatccac aaaattcaag gtcaagttca tcttagaacc agcttcatct
     1681 aggaggtcaa tggccttgtc aggcaagaag cgatcttgga tgtagcgatt ggaaagagtt
     1741 gcagctgctt caatcgcagc atctgtatat tgaacgtggt ggtaatcttc gtatttcttt
     1801 tgaatccctt tgagaatagt gattgtttcg tccaccgttg gttcatcgac tttaacaggc
     1861 tgcatacgac gctcgagggc agcatccttt tcaatgatac ggtattcatt gagggtagta
     1921 gcaccgacta gttgcagttc tccacgagca agggctggct tgaggatatt tcctgcgtcc
     1981 atattaccat cactcgcaga accagcacca acaatttcat ggatttcatc gataaagagg
     2041 atgatgtctt cacgtttgcg aatttcttcc atgagttttt gcatgcgttc ttcaaattgt
     2101 cctcgaatcc ccgttccttg aactaagcta accacatcca gacggatgac ttgtttacct
     2161 tggagtttat gtggcacatc gccatcgaca attttctgag ctagaccttc gacaacggcc
     2221 gtttttccga caccaggttc accgataagg acaggattat tcttggttct acgattgaga
     2281 atctcgatga cacggataat ctcatcgtcg cgcccaataa cggggtcaat gtctccacga
     2341 cgggcaattt cagttacatt aataccaaat tcttccagca ggcctttttc ttggctaggt
     2401 ggcggagttt gagcagatcc acgattttgg gaaccataac cgccgtttcc accgtaacct
     2461 ccacctgatt gggttggggg aataggagga gtattgctag aaggtctgaa attgtttaga
     2521 tcattgaaga aatcaccaaa gggatcgaag tcacgattgt tcagatccgt catacctttg
     2581 aagaggctat tgttaggatc tgttttgata atcttatagc agttttgaca gaggtcaatt
     2641 tgtttttgtt ttccattgag attggtgtaa agatgaattg ttgagtcgtt aattttacag
     2701 ttttgacaaa gcatacatct acctcatttc tttctttagc ctgacttgtt taaaggtcaa
     2761 aaatagtcaa attctatact ctcattataa caggattggg gtgtaaagca agtaaaaaga
     2821 ttgaagcttt gagaagttgt tacaatgaaa atttttgtga atttggacta taaaaaaatc
     2881 ctatttgtga gacaaaaagg attttactta gacatgcagg gacaatccca gcttgtttta
     2941 gattagtaga gaagttcgta aatttccatt gcgattaagt caatgctatc aaacgtatac
     3001 gtttcgcgat cttctacgtc acgaagggta aagattgggc cgttttcttc gtcgtggctg
     3061 tacgcaactt ctgcaacaac aactccttcg cgttcaaaat tacgttttaa atttccgcca
     3121 tcgtttgcca ttgcttcaag gcggttgatg attctaacca aatgtgattc cattttgatt
     3181 ctccttcatt tcttatcgtt actattttac cataaaggag gccaacttga ctagaaaaaa
     3241 ctaagatttc tcgctaattc tgctagttta aagattttta aataaattgg ataaaaaatt
     3301 taaattttaa ttcaaaacat gttataatca tacagtattc tattttagaa agcagtgtga
     3361 ctatgaattt ttctttttta cctaagtatt taccttattt taactatggg gctgttgtga
     3421 cgattcttat ttctatctgt gttatctttt tgggaactat tttgggtgtt gtcttggctt
     3481 ttgggcaacg ttcaaagttt aaaccgcttg tttggttggc caacttgtac gtttggattt
     3541 tccgtgggac accgatgatg gttcaaatta tgattgcctt tgctcttatg catatcaatg
     3601 ctccgactat tcagattgga attttaggtg ttgatttttc gcgtctgatt ccagggattt
     3661 tgattatctc tatgaatagt ggtgcttatg tttcggagat tgttcgtgcc ggaatcaatg
     3721 cggttccaaa aggtcagcta gaggcggctt attcgctagg gattcgtcct aaaaatgcga
     3781 tgcgttatgt gattttgcca caagcagtca aaaatatctt gccagcattg gggaacgaat
     3841 ttatcaccat tatcaaggac agctccctct tatcagctat tggggtcatg gagttgtgga
     3901 atggggctac aacagtttct acaacaacct atctaccttt aacaccactt ttatttgcag
     3961 cattttacta cttgattatg acctctattc tgacagtagc cttgaaagct tttgaaaaac
     4021 atatgggaca aggagataag aaataatgac agaaaccttg ataaaaattg aaaatttaca
     4081 taaatctttt ggaaagaatg aagtattgaa gggcatcaac ctcgagatta aaagaggaga
     4141 agttgtcgtt atcatcggtc cttcagggag tgggaaatct accttgcttc gctctatgaa
     4201 tttgttggag gaagcaacca aggggaaggt tatctttgag ggagtcgata ttacggacaa
     4261 gaagaatgac ctgtttgcca tgcgtgagaa gatgggcatg gttttccaac aatttaacct
     4321 ctttcctaat atgactgtga tggaaaatat taccttgtca cctatcaaga ctaaaggtga
     4381 aagcagggaa gttgctgaga agagagccca agagcttttg gaaaaagttg gtttgccaga
     4441 taaggcagac gcttatccac agagtctgtc gggtgggcaa caacaacgga ttgccatcgc
     4501 gcgtgggttg gctatggaac cagatgtttt gctctttgac gaaccaactt cagccttgga
     4561 tcctgaaatg gtaggtgagg tattggctgt tatgcaagac attgccaagt cagggatgac
     4621 tatggttatc gtaacacatg agatgggatt tgcccgtgag gtggcagatc gtgttatctt
     4681 tatggcagac ggtgtggttg ttgaagatgg gacacctgag cagatttttg aacaaaccca
     4741 agaacaacgg actaaagatt tcttgagtaa ggttttataa tctattttaa aatttcaaga
     4801 caagattagt gaaaagttca accagagctt tttcttatag tttgaaacta taggataacc
     4861 taggaaagaa gtgttagagg gcactagcag tttttggtat aatggaagat atttgaaaga
     4921 aaagagaagt gatatgacac agattattga tgggaaagct ttagcggcca aattgcaggg
     4981 gcagttggct gaaaagactg caaaattaaa ggaggaaaca gctctagtgc ctggtttggt
     5041 agtgattttg gttggggata atccagccag ccaagtctac gttcgcaaca aggagaggtc
     5101 agctcttgcg gctggttacc gtagcgaagt agtgcgagtt ccagagacca ttactcaaga
     5161 ggaattgtta gacctgattg ctaaatataa tcaggatcca gcttggcatg ggattttggt
     5221 ccagttgcca ttaccaaaac atatcgatga agaggcggtt ttattagcca ttgacccaga
     5281 aaaggatgtg gatggtttcc atcccctaaa catgggacgt ctttggtctg gacatccagt
     5341 catgattccc tcgacacctg caggaattat ggaaatgttt catgaatatg ggattgactt
     5401 ggaaggtaaa aatgcggtcg taatcggtcg ttcaaatatc gttggaaaac ctatggctca
     5461 gcttcttttg gctaaaaatg cgacagtaac cttgacccac tcacgaactc ataatcttgc
     5521 caaggtggct gctaaagcag atattcttgt agtcgcaatc ggccgcgcca agtttgtgac
     5581 tgctgacttt gtcaaaccag gtgcggttgt cattgacgtt gggatgaatc gagatgaaaa
     5641 tgggaagctc tgtggagatg ttgattatga ggcagttgca ccacttgcta gccatatcac
     5701 gccagtccct ggaggtgtcg gtcctatgac cattaccatg ctgatggagc aaacttatca
     5761 agcagcactt cggacattgg atagaaaata agagaagcat tcgattaata gagtgtattt
     5821 tctatagcta tatctaaaat ggcagaaatg aatattaaat tttagatata agattacaaa
     5881 aggaggtctg cgtctccttt ttattgtata ataaaagtga gaggaaaaaa ggatgaaagt
     5941 gattaatcaa accttattag aaaaagttat tattgaacgt tctcgttcaa gtcataaagg
     6001 agattatggt cgtctgctgc tgcttggtgg tacttatcct tatggaggtg ccatcatcat
     6061 ggctgcttta gcagctgtaa aaagcggtgc aggattgatg accgttggaa cggacaggga
     6121 aaatatcccg gctctgcaca gccatttacc tgagcctatg gccttttctc ttcaagacca
     6181 gcaattgtta aaagagcaat tggagaaggc agaagttatc ttgctggggc ctggtttagg
     6241 agacaatgct tttggagaag atttagttaa acaggtcttt gctggcttaa aacagaatca
     6301 gattttgatt gtagacggag gtgccttgac cattcttgct aggacaagtt tgtcatttcc
     6361 ctcaagccag cttatcctaa ctcctcacca aaaagaatgg gaaaaattat ctggaattac
     6421 gattgaaaag caaaaggaag atgcaacggc tagtgttctg acttccttcc ctcaaggaac
     6481 aattttggtg gagaaaggcc cagctactcg tatttgggaa gttggccaat ctgattatta
     6541 ccagttacag gttggtggtc cttatcaggc gactggggga atgggagata ctctggctgg
     6601 gatgatcgca ggatttgtag gccaattccg acaggccagt ctctacgagc gtgtggcagt
     6661 agcgacccat cttcattcag ccatagccca agaactatct caagaaaatt atgtggtctt
     6721 accgacggaa atcagcaggt atcttcccaa aataatgaaa attatttgtc aacaagagag
     6781 ggtaagcaaa gataaacttg tttaaaatag acagataaat ctacttcctt ctcttaattt
     6841 atgattcttg aaatgcgcct gctttaaggc taaactagac gtatcaaagt taagagtttg
     6901 tttttgtaac tggaaagaga tgaacaaatc aaatacataa aagataaact catttttatt
     6961 cgttttgtaa aaataaaatg catattttta aagaaagatt gatgaaaaat gtagatttga
     7021 tgtttttact tgaataaaaa gcggtttcat agtaaaataa gaactgagaa tgatggaggt
     7081 aaatcggtgg aaaatctgaa gaaaatggca ggtatcaagg ctgctgagtt cgtgagcgat
     7141 ggaatggtcg ttggacttgg aacaggctcg actgcctatt attttgtcga agaaatcggt
     7201 cgtcgtatca aggaagaagg attgcagatt acagctgtaa caacttctag tgtgaccact
     7261 aaacaggcag aaggccttaa tatcccgctc aagtctattg accaagtaga ctttgtcgat
     7321 gtgacggttg atggcgcgga tgaagtggat agtcagttta atggaatcaa aggcggtggt
     7381 ggtgcccttc tcatggaaaa ggtggtcgca acaccatcaa aagaatacat ttgggtggtg
     7441 gatgaaagca agctggtcga aaaactaggt gcttttaaat tgccagtaga agtggttcag
     7501 tatggtgcag agcaggtctt tcgtcatttt gaacgagctg gctacaaacc aagtttccgt
     7561 gaaaaagacg gtcaacgttt tgtgacggat atgcagaatt ttatcattga cctcgccttg
     7621 gatgtcattg aaaatccaat tgcttttgga caagaattgg accatgtcgt tggtgttgtg
     7681 gagcatggtt tattcaacca aatggtggat aaggtaatcg ttgctggacg agatggagtt
     7741 cagatttcaa cttcaaaaaa aggaaaatag aagggggcat aagatgtcta aatttaatcg
     7801 tattcatttg gtggtactgg attctgtagg aatcggtgca gcaccagatg ctaataactt
     7861 tgtcaatgca ggggttccag atggagcttc tgacacactg ggacacattt caaaaacagt
     7921 tggtttgaat gtcccaaaca tggctaaaat aggtcttgga aatattcctc gtgaaactcc
     7981 tcttaagact gtagcagctg aaagcaatcc aactggatat gcaacaaaat tagaggaagt
     8041 atctcttggt aaggatacta tgactggaca ctgggaaatc atgggactca acattactga
     8101 gcctttcgat actttctgga acggattccc agaagaaatc ctgacaaaaa tcgaagaatt
     8161 ctcaggacgc aaggttattc gtgaagccaa caaaccttat tcaggaacgg ctgttatcga
     8221 tgattttgga ccacgtcaga tggaaactgg agagttgatt atctatactt cagctgaccc
     8281 tgttttgcag attgctgccc acgaagacat tattcctttg gatgaattgt accgtatctg
     8341 tgaatacgct cgttcgatta cccttgagcg tcctgccctt cttggtcgca tcattgctcg
     8401 cccttatgta ggtgaaccag gtaacttcac tcgtacggca aaccgtcgtg acttggctgt
     8461 atctccattt tccccaactg ttttggataa attgaatgag gctggtatcg atacttatgc
     8521 tgtgggtaaa atcaacgata tctttaacgg tgctggtatc aaccatgaca tgggtcacaa
     8581 caagtcaaat agtcatggaa ttgatacact attgaagact atgggacttg ctgagtttga
     8641 aaaaggattc tcattcacaa acctagttga ctttgatgcc ctttacggcc atcgtcgtaa
     8701 tgctcacggt taccgtgatt gcttgcatga gtttgatgaa cgcttacctg aaattatcgc
     8761 agctatgaga gagaatgacc ttctcttgat tactgcggac catggaaatg acccaacgta
     8821 tgcaggaacg gatcacactc gggaatatat tccattgttg gcctatagcc ctgcctttaa
     8881 aggaaatggt ctcattccag taggacattt tgcagatatt tcagcgactg ttgccgataa
     8941 ctttggtgtg gaaactgcta tgattgggga aagtttctta gataaattgg tataagatga
     9001 cgcgctatgc tttgctggtg agaggtatca atgttggtgg taagaataag gtcgtcatgg
     9061 cggagcttcg tcaagaattg acaaacttgg gactggaaaa ggttgagagc tacatcaata
     9121 gtggcaatat tttctttact tcgatagatt ccaaagccca attggttgaa aagctagaga
     9181 ctttctttgc agtccattat ccatttattc agagcttttc tttactgagt ctagaggact
     9241 ttgaggcgga acttgaaaat ctaccagctt ggtggagcag agacttggca cgaaaagatt
     9301 ttctctttta cactgagggt ttggatgtgg accaagtcat cgcgacagtt gaaagtttag
     9361 agctgaaaga tgaagtgctt tattttggaa aacttgggat tttctggggg aaattttctg
     9421 aagaatccta ttctaagact gcctatcata agtacttgct gaaggtgcct ttctaccgcc
     9481 acattactat tcgtaatgct aaaacctttg acaaaattgg tcaaatgcta aaaaaataat
     9541 aaaggagaca cacaatgaca tttttaaaca aaatccatga aactgctact ttcctgaaag
     9601 aaaagggaat tgcagcccct gagttcggtc taatccttgg atcaggactt ggagaattgg
     9661 cagaagaaat cgaaaatcca gttgtagtag actatgctga gattccaaac tggggccgtt
     9721 caacagtagt cggtcatgct ggtaaattgg tatatggtga actggcaggt cgcaaggtct
     9781 tggctcttca agggcgtttc catttctatg aagggaatcc tctggaagtg gtgactttcc
     9841 cagttcgtgt gatgaaagtt cttggatgtg aaggtgttat tgtaaccaat gcagctggcg
     9901 gtatcggatt tggtcctggt accttgatgg ctatctcaga ccatatcaac atgacggggc
     9961 aaaatccatt gatgggtgaa aacttggatg actttggccc acgtttccca gatatgtcta
    10021 gggcctacac accagaatac cgtgccactg cccatgaagt ggctaaaaaa cttaatatca
    10081 agcttgatga aggtgtctat atcggagtta ctggtccgac ttatgaaaca ccagcagaaa
    10141 ttcgttccta taagacactg ggagcagatg cagttggtat gtctacggtt cctgaagtta
    10201 tcgtggcagc ccactctggc ttgaaagttc tgggaatttc atgtatcact aactttgcgg
    10261 ccggtttcca agaagaactc aatcacgaag aagttgtaga agtgactgaa cgtgttaaag
    10321 gtgatttcaa aggcttgctt aaagcgattc ttgctgaatt gtaagaaaaa agatttaaaa
    10381 gggggagtgc ctctgttttt tcaggattga ctgcctatcc ggattaaaga agaaacagag
    10441 gaatactatg agcttcttcc tgctcttata actgaaagaa gcggaagaat aggtatgtct
    10501 gatctgatag ccagcattgt gaaagacaag attctaggat actagcatta gcttcctagc
    10561 caagcagact agtatgataa ggagagatga gaatgaattg actttctgaa tttctcagtc
    10621 ttatcatata tagcacaatg agatttcgct tgagtctgct tgtaaataaa cgaaaagaaa
    10681 gataagaaat aatgaaaatt ggtcaacgaa ttatgcgctt tggcataaaa aattaagtat
    10741 cggagttgta tctgttgtag tcggctttga tttctagctc cagctggaat ttcagccaat
    10801 gaagtaaagc aagatgtaac atctgaagtg gtaataggtg tgctagattc taaggaggaa
    10861 ttgaaagagt cagaaaatga tgctccaaaa ctagaaactc ctcttagaga ggagccaaga
    10921 ctagctcctc aaacgcttcc ggaagcaagt gaagttcttg aaaacaaaag ggaagagtca
    10981 aaagtagaga taacataacc agctcaagcg gatgatatcc gcaaggttgt tggggaatta
    11041 gccaaggata taagtattac taagttgtat atgacaggtc attctcttgg atgttaccta
    11101 gctcagattg cagcggttga agcttaccaa aaatatcctg atttttataa ccatgtattg
    11161 aggaaagtga caactttcag tgctcctaaa gtgattactt ccagaactgt ttggaatgct
    11221 aagaatggtt tctgggatgt tggtttggaa agtcgtaaat tagctgttag tggaaaaatt
    11281 aagcattatg tggttgataa tgacaatgtt gtgactccct tgattcataa taatcgtgat
    11341 attgttacat ttacaggtaa ttcacgcttt aaacaccgtt ctcgtggcta ttttgaaagt
    11401 ccaatgaatg atattcctaa ctttaatatt ggtaaacaag ctaccttgga taaacatggt
    11461 tatcgtgatc cgaaattgga taaagtgcga ttctttaaga aacaggctct gcctcgatct
    11521 tctagtcaac caagcgctga accaatggaa aatattgcct taggaaaaca ggttactcaa
    11581 agttcgacag ctttcggagg agatgctaga agagctgtgg atggcaaagt cgatggtaac
    11641 tatggtcaca attctgtcac tcatacaaac ttccaatcta agccttggtg gcaagtagat
    11701 ttggctaaag aagaaaccat tcgccaaatc aatatttaca accgaacaga cactgcccag
    11761 gatagattgg caaactttga tgtcattctt ttagacagtt ctggtaaaga aattgagtga
    11821 aaacgtataa tatctcctaa agatgtgtca gcacaaatta cgattaacca taaaaaagcg
    11881 cgctatgttc ggattgagct agaaggctat aatgccctca gtcttgcaga agttgaagtt
    11941 ttccgcttta tagctacgaa tgctgaaacg gcgacacaag tttctaagcc agttcaacca
    12001 atcagtcaga ctcctgtgaa agataaaaca ttgacaattc aacacagtgg agcttacatt
    12061 gcccgctact ccataacttg ggaagaagtt ccagtagata aagatggaaa ccaagttgtt
    12121 cgtagtcatt cttgggaagg aaacggtcgc aaccagactg cgggttttgt cctcaacctc
    12181 ccaatcaaag aaaatatgag aaatctgcga gttaagattg agaaaaagac gggcctacta
    12241 tggaatagat ggcaaacaat ctatgaaaac agaccaattt cagctcaacc ccaccgtaaa
    12301 attacccatt ggggtacgac attgaattcc aaggtgagtg acgatgatgt cttgtaatct
    12361 gatggtacaa tgacagttag tttgtctagt ttataagaaa gtactacctg agcttgaata
    12421 gaactcaggt agctctctgt gaaagaacaa aattaatact caatgaaaat caaagagcaa
    12481 actaggaaac tagccgcagg ttgctcaaag cactgctttg aggttgtaga taagactgac
    12541 gaagtcagtc acatatataa tccaaggcga cgttgacgtg gtttgaagag attttcgaag
    12601 agtataaaca gaaaggtaga gcgcgtgttc taatttgaac acgagtagaa aacttttcta
    12661 aaaacaaaaa cgaaaggatg ggtaaactgt attcgctgaa ctgaatacgg gcgactctcc
    12721 tctaaatcaa aattaagaaa ggaattgacc ccaccctaaa agtagtggga aaaagatagt
    12781 tggtctagcg agcatcgctc actgcgccca actcctattt tcccttcgct ttttgatggg
    12841 tttggtatct ttctcaatat aaaataaaga aaggtagagc gtgtgttttg atttgaacac
    12901 gagcggaaaa ctcggaaaat agataatctg actgaaaaat caggatttct cgtcaggttc
    12961 ctaattttca gtcgttttct tctcgctctt tgtatcataa attatgtcta tccatattgc
    13021 tgctcagcag ggtgaaattg ctgataaaat tcttcttcct ggggatcctc ttcgtgctaa
    13081 gtttattgcg gagaatttcc ttgatgatgc tgtttgtttt aacgaagtgc gtaacatgtt
    13141 tggttacact ggtacttaca agggtcactg tgtatctgtc atgggaactg ggatgggaat
    13201 gccatctatt tcgatttatg cgcgtgagtt aatcgtagac tacggtgtga agaaattgat
    13261 tcgtgtggga actgcaggtt ctttgaatga agaggttcat gttcgtgaat tagttttggc
    13321 gcaggcggct gcaaccaact caaacatcgt tcgtaatgac tggccacagt acgattttcc
    13381 acaaattgct agctttgatt tgcttgataa agcctaccat atcgccaaaa aacttggtat
    13441 gactactcac gttgggaacg ttttgtcatc tgatgtcttt tactcaaatt actttgaaaa
    13501 gaatatcgag cttggtaaat ggggagtcaa ggctgtggaa atggaagcag cagctcttta
    13561 ctatcttgct gcccaatacc atgttgatgc gctagctatc atgaccatct ctgatagctt
    13621 ggtcaatcca gacgaagaca caactgcaga agaacgtcaa aataccttca ctgatatgat
    13681 gaaggttggt ttggaaacct tgattgcaga ataattatag ccaaaaagga agccctttat
    13741 gaattgtagg acttcctttt cttatccaga aattgatcta gctctctctg atttcgaaga
    13801 atagtgactt tatgtgaata ttcttggcaa agtttttggt aattttcttt ttgagttttg
    13861 ctacgcccat cccaaagaat ccatctgata aactcccact caaagcgttc agggcaatct
    13921 gccgccatac tttctctgac ttttccacgg tatttaagat aacgcttaaa ggctctaaag
    13981 agacaggtca atggcgaaaa attgagaaag atgatttggt cagcttcttg cattcgttct
    14041 tggtagtagc accaagaata attaccatcg atgacccaag ctttatgctt ggtgagaaag
    14101 ttttttatct cggttaacat ccattcgcag tcactgtctt gccaaccagg ttgaaattgg
    14161 agtgtgtcca tgtgcagttt tggaatggag tagtagttag ataacttttc tgctatagtt
    14221 gacttaccag aaccagaata tccgataatt gcgattttca ttttctactt tttcctattt
    14281 ggagacaaaa aaacagcctc tatggactgt ttcttattta gcaagtttag ctgaaagacg
    14341 agctttatcg cggcttgctt tgtttttgtg aatcaaacct ttagtttctg ctttatcgat
    14401 agctgagcta gcagcacgga aaagttcttc agatgggttt gcttcgaaag cttttatagc
    14461 agtacgcata gctgattttt gagctgagtt cttttcgttt tgtttaacgt tcaattcagc
    14521 gcgtttgata gctgatttaa tgtttgccaa tgttcttacc tccatattta ctaactatac
    14581 cattatatat gaaaacttac gttttgacaa gggaaaatta cttttttaag taaatttcat
    14641 cgatttcatg gttcttgctt ttatgaagaa tcacttctgc acgatttctg gttggttcaa
    14701 tataattttg cagatttgtg agattgatac tgatccagac ctgatgggca aaggactcca
    14761 cttccccaat cggcatctga gtaaaacgat aatagtagct atcagggtcg ttttgggcta
    14821 ggctcagcat tttcaagaaa cggtccagat accaactttc aatatcatcc actccagcat
    14881 ctacatagat ggaaaagtca aagaagtcag tgatatagag acgatcgttt tgtggatttt
    14941 gaaagacatt aattccctca acaattacaa aatcagcagc tttgacactt tgtttctttt
    15001 cgggtacgat gtcgtaaact tcatgagaat agacaggaat atctacatct tgtccatttt
    15061 tgatgcggtc caagaagttg agaagagctt ccatatcata gctttcagga aatcctttac
    15121 gatttaaaat cccctgctca atcaaggttt gattgggata gagaaaacca tcagttgtaa
    15181 ccaactcaac cgtagcatct gtaaacgtac gggacagtag gatttgaagt aggcgactgg
    15241 ttgtggattt tccaacggca acactcccag aaaccccaat aataaaaggt tgagatttac
    15301 tttcacgttg gaggaaaatt ccttttgaaa aggctaaatc ttccttagtt cgcttgtaaa
    15361 tctgaatcag atgagccaag gggagataga tatctgtaac gtcttggaga ctgatttggt
    15421 cattaaaact cttgatagat tccaattctt cttctgtcaa aggaggtgtt gtctttcgat
    15481 gtaaagattg ccaagtctgg cggctgattt tttcaaaatg taaaaattcg ttggtcattt
    15541 gttttcccct agatattttg tctatcatac cataaaaagc taaaaaaata aagcggtttc
    15601 ttgaatgtgg taagtcaatg gtatatagta taagtgatca atttattgat gaaataggag
    15661 atagattcta ctgatttata agcttataaa gggggctttt tagttcacaa cttataggag
    15721 gtgtactatg aaaatcttaa aacgttacat attggaactc tgttttattt taagttttgc
    15781 tttacctttt ataaaaggaa ccaatgcaga taatggtaga tgctttgtgg aaacctatta
    15841 cggttttact tttttgatgg aacatgctat tgtaacagct gtctttatct attcgttttt
    15901 aattgctttc ttactaaaaa aacgatgggc gaaatggatt gctgctggta gttattgctt
    15961 tttagtccta tggattgcga cagagggtta tttcttccgc atgtcactag aagatttgat
    16021 acgactttgg acaagtttgg aaatcctgac acaaacgtat cagttgggct tttatctaaa
    16081 cattttgtta ggaattttgt tgataataaa gtattttaag gttaagcaat agaaataata
    16141 atctgcctga ttatagatga taaacttttt gtttttatct ggactgtgat atttatagtt
    16201 ctaaatggtt tattatttat aagtgttgaa agagattgaa gaaaatggct tcgtgacttg
    16261 ctttcttcgg tctttttcgt tttattatca atttgtaaac gatttacaat ttgagtcaaa
    16321 ttatggtaaa atagtgtcat gagtaaaatg tattatgcag aaaatcctga cgctgctcac
    16381 gacattcatg agttgagagt ggacttgttg ggacaaaaaa tgactttttt gacagatgcg
    16441 ggtgttttta gcaagaaaat ggttgacttt ggaagtcaac tcttgctcaa gtgtctggat
    16501 gtcaaccaag gagagacagt cctagatgta ggctgtggtt atggtccatt aggtttgtcc
    16561 ttggtcaagg tttacggagt tcaggcgacc atggttgata ttaacactcg tgccttggat
    16621 ttagctcgga gaaatgctga aaaaaataat gcaaaagcga cgattttcca gtccaacatc
    16681 tatgaacaag ttgaaggaca ttttgatcat gtcatttcca atcctcctat ccgtgcgggc
    16741 aagcaagtcg ttcatgaaat cattgagaaa agtaaagatt tcttggaaac tggtggggat
    16801 ttgacaatcg tcatccagaa aaaacaaggg gctccaagtg ctaagtccaa gatggaggat
    16861 gtgtttggta attgtgaaat ccttaaaaaa gacaaaggat actatatcct tagaagtgtg
    16921 aaagaatgag agcagttgat ttaatacaaa aaaaacgaga cggtcaagaa ctgacttcaa
    16981 gtgaaattga atggctggta gaaggctatg tgtcaggaac tgttcctgat tatcagatgt
    17041 ctgcctttgc tatggctgtt tattttaaag gaatgacgac tcgtgaaatt tctgatttaa
    17101 cgatgaatat ggttaagact gggcaagagt ttgacctgtc agccattgat ggtgtgaaag
    17161 ttgacaagca ttctactggt ggtgtcggcg ataaggtaac cttgatttta gctcctcttg
    17221 ttgctagctt cggtgtgcct gtagcaaaaa tgagtggtcg tggtcttggc catacaggcg
    17281 gaacaattga taaattggag tccattaggg gctatcaagt agaacgtagt caagaggatt
    17341 ttattcgtca ggttcaggat attggagtat ctgtcattgg gcaatcagac cagctggtca
    17401 aagcagataa gcttctctat gcccttcgtg atgtgaccgc aactgtcgac acgattcctt
    17461 tgattgcgag ttcggtgatg agcaagaaaa ttgcggcagg ggcggatgct attttgctag
    17521 acgtgactgt cggtgagggt gccttcatga agacggttga tgaggcgcgt gagttggctc
    17581 aaactatggt agatcttggt aaggttgttg gacggaagac agtagcagtg attacggata
    17641 tgagccagcc tttgggacga gcgattggaa atcgtctgga aatacttgaa gcattggaga
    17701 ttttgcaagg tcaaggacgt caggatatta cccactttat ttgtgaattg gctcaaatta
    17761 tgcttggttt ggcaaatgtt aacaagactg ttgaagaagt tcaccaacat cttgagaatg
    17821 gtcaagcact ggctaagttt gaggaaatgg tgcaagccca aggtggagac ttggaagacc
    17881 tctatcgtcc tgtaaatgta gctcatgtgg tggaaatccc tgctcaggaa acgggtgtca
    17941 tttcagctct tccagctatg gactttggtc tttatgccat gaggctgggg gctggtcgtg
    18001 cagttaagtc tgatgccttg gactatgaaa caggaattgt ttttgaaaag aagattggag
    18061 actccgttca aaagggtgaa attgttgcaa aagtatacac aaatgaaaaa attccacctc
    18121 aactagttac agatttccaa aaatgtgtta aaataagtga tgaagtgaaa aaaatccgtg
    18181 aaattgtaga aatcatctcc taaatggagg gaaaaccgaa atgaaattaa ataaatatat
    18241 agatcatacg cttttaaaac aagatgcaaa gaaaaaacaa attgatagtt tgttgtctga
    18301 ggctagagag tatgactttg ccagtgtttg cgttaatccg acctgggttg aacatgctaa
    18361 aaaaggactt gaaggcacag atgttaaggt ttgcacggta gtaggtttcc ctttgggagc
    18421 aacaacttca gccgtgaaag catttgagac aaaagaagct atccaaaatg gtgcagatga
    18481 gattgatatg gtgatcaatg ttggagctct caaatcaggt aatttagcct tggttgagtc
    18541 agatattcgc gcagtagtgg aagcaagtgg tgataagtta gtgaaagtca ttattgaagc
    18601 ttgccttctg acagaccaag aaaaaattgt tgtttgccaa ttggcccaaa aagctggggc
    18661 tgactttgtt aaaacatcta ctggtttttc aactggtggt gctacgatag cagatgttac
    18721 attaatgcgt gaaacagttg gatctgatat gggagtcaag gctgctggtg gagctcgttc
    18781 ttatgcagat gctcttgcct ttgtcgaagc aggtgcgacc cgtatcggaa cgtcagctgg
    18841 ggtagctatt ttaaaaggag aattggcaga tggcgactac tgagttgatt gaactggcaa
    18901 ttgaaaccag caaacatgcc tatgtcccct attctcactt tcctatcgga gcagttttag
    18961 tagccaaaga cggaagtgtt tacacgggag tgaatatcga aaatgctagc tatcctttga
    19021 ccaattgcgg tgagagaaca gctattttta aggctatatc tgaaggccaa agagaatttt
    19081 cagaattgat tgtctatggt caaactgaaa aaccgatctc gccatgtggt gcttgtcgcc
    19141 aagtgatggc tgaatttttt gaacaagatc taaaagtgac cttagtcgca aaagataaat
    19201 cgacggtcga gatgacggtc ggggaattac ttccatactc ttttacagac ttaaactagt
    19261 ctgagtcgct ctctgagtgg cacggtcctt gtggccaacc aatccatact tgcaacatcg
    19321 ttgcacatct tatttaggag gttcagtaat gaacaagaaa caatggctag gtcttggcct
    19381 agttgcagtg gcagcagttg gacttgctgc atgtggtaac cgctcttctc gtaacgcagc
    19441 ttcatcttct gatgtgaaga caaaagcagc aatcgtcact gatactggtg gtgttgatga
    19501 caaatcattc aaccaatcag cttgggaagg tttgcaggct tggggtaaag aacacaatct
    19561 ttcaaaagat aacggtttca cttacttcca atcaacaagt gaagctgact acgctaacaa
    19621 cttgcaacaa gcggctggaa gttacaacct aatcttcggt gttggttttg cccttaataa
    19681 tgcagttaaa gatgcagcaa aagaacacac tgacttgaac tatgtcttga ttgatgatgt
    19741 gattaaagac caaaagaatg ttgcgagcgt aactttcgct gataatgagt caggttacct
    19801 tgcaggtgtg gctgcagcaa aaacaactaa gacaaaacaa gttggttttg taggtggtat
    19861 cgaatctgaa gttatctctc gttttgaagc aggattcaag gctggtgttg cgtcagtaga
    19921 cccatctatc aaagtccaag ttgactacgc tggttcattt ggtgatgcgg ctaaaggtaa
    19981 aacaattgca gccgcacaat acgcagccgg tgcagatatt gtttaccaag tagctggtgg
    20041 tacaggtgca ggtgtctttg cagaggcaaa atctctcaac gaaagccgtc ctgaaaatga
    20101 aaaagtttgg gttatcggtg ttgatcgtga ccaagaagca gaaggtaaat acacttctaa
    20161 agatggcaaa gaatcaaact ttgttcttgt atctactttg aaacaagttg gtacaactgt
    20221 aaaagatatt tctaacaagg cagaaaaagg agaattccct ggcggtcaag tgatcgttta
    20281 ctcattgaag gataaagggg ttgacttggc agtaacaaac ctttcagaag aaggtaaaaa
    20341 agctgtcgaa gatgcaaaag ctaaaatcct tgatggaagc gtaaaagttc ctgaaaaata
    20401 atggatggaa gtcatttctt aggaagcggc caagggccgc ttttttaaga gttgagacaa
    20461 agtcattttg tctcagtaaa gcttgctact agacaaacta gcaagtttta ttgaaataaa
    20521 ataagactct gaaaggaaga gcacatggca cacgaaaatg tcattgagat gcgtgatatt
    20581 accaaggtgt ttggtggatt tgttgccaac gacaaaatca acttgcacct acgaaaaggt
    20641 gaaattcatg cacttttagg agaaaatggg gctggtaagt ccacgctaat gaacatgtta
    20701 gcaggccttc ttgaaccaac tagtggtgaa atcgcggtca acggtcaagt tgtcaatctc
    20761 gactccccat ctaaagcagc tagcttggga atcgggatgg ttcaccagca ctttatgttg
    20821 gttgaagcct tcacagtggc tgaaaacatc attttaggta gtgaattgac taaaaatggt
    20881 gtgctagata tcgctggagc tagcaaagaa atcaaggctc tttctgaacg ttatggctta
    20941 gctgttgacc cttctgccaa ggtagcagat atctcagttg gagcccaaca acgtgtagaa
    21001 attttaaaaa cactttatcg gggggctgat atccttatct ttgacgaacc aacggctgtt
    21061 ttgactccat cagaaattga tgagttgatg gctattatga aaaatcttgt caaagaagga
    21121 aaatcaatta tcttgattac ccacaaattg gatgaaattc gcgcagtttc tgaccgtgtt
    21181 acagttatcc gtcgtgggaa atcaattgaa accgttgaaa ttgcaggggc taccaatgct
    21241 gatttggcgg aaatgatggt aggacgttct gtttccttta aaacagagaa gcaagcctct
    21301 aaaccaaaag aagtggtttt gtctatcaaa gatttggtgg tcaatgaaaa ccgtggtgtt
    21361 ccagctgtta aaaatctgtc cttggatgtt cgtgctggag agattgttgg tattgcgggg
    21421 attgatggaa atggtcagtc tgaactgatt caagccatta caggtcttcg taaggttgaa
    21481 tctggtagca ttgagctaaa aggagattca attgtaggct tgcacccacg tcagattaca
    21541 gaactaagtg ttgggcacgt tccagaagac cgtcaccgtg atggcttgat tttggaaatg
    21601 atgatatctg aaaatattgc ccttcaaacc tactataaag aaccacatag taaaaatgga
    21661 attttgaatt attcaaatat tacttcttat gctaaaaagc tgatggaaga gtttgatgtt
    21721 cgcgctgcca gtgaattagt tcctgcagct gcactctcag gaggaaatca acaaaaagca
    21781 attattgctc gtgaaattga tcgagatcct gatctcctta tcgttagcca gccaactcgt
    21841 gggttggatg tcggtgccat tgagtatatc cacaaacgct tgattgaaga gcgtgataat
    21901 ggcaaggctg tccttgttgt cagctttgaa ttggatgaga ttttaaacgt ctcagaccgt
    21961 attgccgtta tccacgatgg taagattcaa ggtattgtat caccagaaac aaccaataaa
    22021 caagaacttg gtgtcttgat ggctggtgga aacttgggaa aggagaagag tgatgtctaa
    22081 aaaattacaa caaatttcgg ttcccttgat ttctgtattt ctaggaattt tactcggagc
    22141 cattgtcatg tggatcttcg gttatgatgc tatttggggc tacgaagaat tgttctatac
    22201 agcctttggc agtctgcgtg ggattggaga aatcttccgt gctatgggtc ctctggtctt
    22261 gattggtctt ggttttgcgg ttgccagtcg agctggtttc tttaacgtcg gacttcctgg
    22321 tcaggctttg gcaggttgga ttctcagtgg ttggtttgcg ctgtcgcatc cagatatgcc
    22381 ccgtcccttg atgattctag caaccatcgt gattgccttg attgctggtg ggattgtcgg
    22441 agcgattcca ggtattctta gggcctatct agggacgtca gaggttattg taaccatcat
    22501 gatgaactac attgtcttgt atgtagggaa tgcctttatc catgctttcc ctaaagactt
    22561 catgcaaagt acagattcga ccattcgtgt tggggctaat gcaacctatc agacaccttg
    22621 gttggctgag ttgactggta actcacggat gaatattggt attttctttg ccatcattgc
    22681 cgttgcagtt atttggttca tgctcaagaa aacaactctt ggttttgaaa tccgtgcagt
    22741 tggtcttaat ccacatgctt cagaatatgc tggtatttct gccaagcgga ctattatcct
    22801 atctatgatt atttcaggtg ccttggcagg tcttggtgga gctgttgaag gtttgggaac
    22861 cttccagaac gtctatgttc aaggttcgtc attagctatc ggatttaacg gaatggcggt
    22921 tagtttgctt gcggccaact caccaattgg tatactcttt gcagccttcc tatttggcgt
    22981 tctccaagtt ggggctcctg gtatgaatgc ggcgcaggta ccatctgagc ttgtcagcat
    23041 tgtaacagcg tctattatct tctttgtcag tgttcattac cttatcgaac gctttgtcaa
    23101 accgaaaaaa caagttaaag gaggtaagta aagatgtcta ttataacctt gctccccctc
    23161 ttggtgtctt ctatgctgat ttactcagca cctctcatct ttacaagtat cggtggtgtt
    23221 ttctctgaac gtggtggtgt ggtaaacgtt ggccttgaag gaattatggt tatgggtgcc
    23281 ttttctggag ttgtctttaa ccttgaattt gcagaacaat ttggagcagc aactccatgg
    23341 ctatccttgc ttgtagcagg attggttggt agtgttttct ctatcatcca cgcagcagcg
    23401 acggttcatt tccgtgcaga ccatgttgtc agcggtacgg tattgaactt gatggcgcct
    23461 gccttggctg ttttcttagt taaagttctt tataacaaag gacaaaccga caacctaagt
    23521 caaacttttg gacgctttga tttcccagtc ttggcaaata tcccagtgat tggtgatatc
    23581 ttcttcaagt caactagtct acttggttat ctggcgattg ccttctcatt ccttgcttgg
    23641 tttattctct ttaagactca atttggtctt cgtctccgct ctgtcggtga acatcctcaa
    23701 gcagcggata ccttgggaat caacgtctac aagatgagat atttagggat tattatttca
    23761 ggttttctag gtggaattgg cggagcgatt tatgcgcaat caatctcagt taacttctca
    23821 gtgacaacta ttgttggacc tggatttatc gcccttgctg cgatgatctt tgggaaatgg
    23881 aatccaatcg gtgctatgct ttctagtctc ttctttggac tttcacaaag tttggctgtt
    23941 atcggttctc aattgccgtt cctacaagga gtgccagcgg tttatcttca aattgcacct
    24001 tatgttttga caattcttgt cttagcagcc ttctttggaa aagcagtcgc accaaaagca
    24061 gatggtatca actacatcaa atcaaaataa gcatacaaaa aaacgtcagt ccaatgactg
    24121 aactgccccc caaaagttag acagaaaaaa tctaactttt ggggtg
//
LOCUS       DAVAZV010000030        23540 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVAZV010000030 DAVAZV010000000
VERSION     DAVAZV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23540)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23540)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23540
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.030"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            351..611
                     /locus_tag="VQT46_001188"
     CDS             351..611
                     /locus_tag="VQT46_001188"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2371224.1"
                     /translation="MSGGETKRVALAKIILKNPPLIFADELTASLDSTTSQGIMKLLL
                     GMKNKNRLIIIATHNPDIWNQADEVINLNQLLQSIYIFYILK"
     gene            complement(715..1185)
                     /locus_tag="VQT46_001189"
     CDS             complement(715..1185)
                     /locus_tag="VQT46_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2371225.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQTLLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(1202..3475)
                     /locus_tag="VQT46_001190"
     CDS             complement(1202..3475)
                     /locus_tag="VQT46_001190"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET2371226.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGKAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLASDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCETFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            3822..6923
                     /locus_tag="VQT46_001191"
     CDS             3822..6923
                     /locus_tag="VQT46_001191"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET2371227.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQGVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRLAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSLEAGHTVEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNSSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIENRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEVREGAFYYIKGKVQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSDELEAKLNEIVMKT
                     IYR"
     gene            7005..8012
                     /gene="pfkA"
                     /locus_tag="VQT46_001192"
     CDS             7005..8012
                     /gene="pfkA"
                     /locus_tag="VQT46_001192"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET2371228.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            8069..9574
                     /gene="pyk"
                     /locus_tag="VQT46_001193"
     CDS             8069..9574
                     /gene="pyk"
                     /locus_tag="VQT46_001193"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET2371229.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(10306..10531)
                     /locus_tag="VQT46_001194"
                     /pseudo
     CDS             complement(10306..10531)
                     /locus_tag="VQT46_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            11379..12251
                     /locus_tag="VQT46_001195"
     CDS             11379..12251
                     /locus_tag="VQT46_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET2371230.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(12397..12741)
                     /locus_tag="VQT46_001196"
                     /pseudo
     CDS             complement(12397..12741)
                     /locus_tag="VQT46_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            12884..13174
                     /locus_tag="VQT46_001197"
     CDS             12884..13174
                     /locus_tag="VQT46_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371231.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEYPELYAVAQTSGEIPEKNAKNCVRLSQLSLNKR"
     gene            13198..13914
                     /locus_tag="VQT46_001198"
     CDS             13198..13914
                     /locus_tag="VQT46_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2371232.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(14043..14858)
                     /locus_tag="VQT46_001199"
     CDS             complement(14043..14858)
                     /locus_tag="VQT46_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET2371233.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(14855..15760)
                     /locus_tag="VQT46_001200"
     CDS             complement(14855..15760)
                     /locus_tag="VQT46_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET2371234.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMLFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
     gene            complement(16031..16114)
                     /locus_tag="VQT46_001201"
                     /pseudo
     CDS             complement(16031..16114)
                     /locus_tag="VQT46_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            16158..18287
                     /locus_tag="VQT46_001202"
     CDS             16158..18287
                     /locus_tag="VQT46_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET2371235.1"
                     /translation="MDKKYEKISQDLGVMLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            18274..18723
                     /locus_tag="VQT46_001203"
     CDS             18274..18723
                     /locus_tag="VQT46_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET2371236.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            18782..19054
                     /locus_tag="VQT46_001204"
     CDS             18782..19054
                     /locus_tag="VQT46_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2371237.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(19102..19266)
                     /locus_tag="VQT46_001205"
     CDS             complement(19102..19266)
                     /locus_tag="VQT46_001205"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371238.1"
                     /translation="MDEAGEILLILFKNQSANYVNFTLPTKLQPVAGFLVCTLIFIEY
                     KSKKALNQAV"
     gene            complement(19408..19599)
                     /locus_tag="VQT46_001206"
     CDS             complement(19408..19599)
                     /locus_tag="VQT46_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371239.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            20027..20785
                     /locus_tag="VQT46_001207"
     CDS             20027..20785
                     /locus_tag="VQT46_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371240.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            20787..22775
                     /locus_tag="VQT46_001208"
     CDS             20787..22775
                     /locus_tag="VQT46_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371241.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYSVKEKEVLRYSNFGIANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKALTLNDHQFSVKEEFTKDFIVNHVPNQF
                     NILTADYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVNASEAEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(22817..23461)
                     /locus_tag="VQT46_001209"
     CDS             complement(22817..23461)
                     /locus_tag="VQT46_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET2371242.1"
                     /translation="MLRAGVLDANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNEEFKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLEQLFSI"
BASE COUNT         7225 a         4238 c         4967 g         7110 t
ORIGIN      
        1 tctagtaatt ttgtgataaa atgtaattgt tccatatgaa tctttctaat gagttgtttt
       61 gtcgcttttc attataggtc atatgggact ttttttctac aataaaatag gctccataat
      121 atctatagtg gatttaccca ctacaaatat tatagaaccc ttttttattg acagtatcag
      181 gatatctttt tcaaattttt ggtttgttag ataatgaaaa tgtttctatc aatctagatt
      241 taggattaat aaatcgtaaa tgtaattata aagaaaaaga taagttaaaa aaagatgtat
      301 tagcaagagt tggtctaact catattcatc tataacaaaa gatatatgaa ttgtctggcg
      361 gtgaaacaaa acgtgttgct ttagcgaaaa tcattcttaa aaatccacca ttaatattcg
      421 cggatgagtt gactgcatca ctcgattcga cgacttcaca aggaattatg aaattgttat
      481 taggtatgaa aaataaaaat cgtctaatca tcattgcaac tcataatccc gatatttgga
      541 atcaagcaga tgaagttata aatttaaatc aattattaca gtcaatatat atcttctata
      601 ttttaaagta attttatctg aatccgttaa gagactattg tcccaggctc tttctgatgt
      661 taaagacttt ctaccaggtt ttttaaaagc ataattgtta gttgtagtca tttattattc
      721 ttcaaagaaa aatggtgggg cgaatttttt cagttcttca aagcactttt gagcagtatc
      781 tgcatcttca cagatgataa gacagacatc attaccacaa agggtagcga tagcgtcagg
      841 gaagctcaaa gtatcaatga tagaaccaaa ggattgagcc agtccaggaa gggtttttag
      901 taggacttgg tgttgaactg ggcgcatcca gacaagggcg tcttccatgt agagttcgag
      961 acgtttttcc cattttgaga tggaaccatt gttaagaaca taataagcgc tatcttcttc
     1021 gcggactttt gataggttca tatttttgat gtcgcgtgag agggttgcct gagttacttg
     1081 aatgtcgttc tcagcaagaa gggtttgcaa ctcagcctgt gtatgaatct tgttttttgt
     1141 gataagagcg cgtataagtt ggtggcggtg ttctgattta ttcataataa tgtaactcct
     1201 tttagcaagg taaggtaagc atggactgag cgaggtcgac agtcaagtgg tagtctgtat
     1261 tgtcacggat ggtgatttca aagtcagtag tatagaggac taaacggaga gtgtctcctt
     1321 cttttagctt gtaaatagtt ggctgcagtt caaattgaac gtccatccat tcatctgcag
     1381 taatatcctc tactaacagt aaatcatttc tattttgtaa attaaggtaa ccttttgtca
     1441 cgactctttg tgcctctggt ctaaatggca attcacagag attttccaac atgtgatagc
     1501 gaccgttgtc aatggttcta gcacttaaaa tagctggata aggttgtagg tatttctttt
     1561 gcccaaattc tagcagttgg gcagataaga gccccttgtt tgtactggat ttgatacgaa
     1621 gattgagctg agcgcgaccg tttaggtgga gatctttagt cacaggaagg ttaatagtaa
     1681 tctgattagc tttcccttga tagagctctg tattgaaggt ttggtatgtc ttaccatagc
     1741 gctcaaaatc cttatctggg tactggtttt gaatagcttg ctcttcttga ccaagtgaga
     1801 aggtttcaca gttttcttgc ccaccgaagt tatcaagtga taaccaagtc tgtggagctg
     1861 tattgtcctg ccagataaca gtaggaagtt gaaagtctgt ttcctgtcct agtaatttct
     1921 tggtcaataa ggcatttatg gactcacgga agtcaattga ttgccaattg ttcatgtaaa
     1981 catgggcacc attatggaaa aagagatgct tgtgtatatg agtaggaaga gcatggaaca
     2041 tctggtaaac atgaagtggt ttgacattcc aatcctgaga accatgagta aagacaacct
     2101 ctgcctttac tttatgggca ttgagcagat aattgcggtc atgccaaaac tgattgtagt
     2161 ccccagtttt tcggtctagt tgagctttca ctttttctaa gtcagcttgg tgagcttcat
     2221 tgccacggat atagtcgcta gccaagagat tacgagaata ggttaactca gcaagggagt
     2281 caaagtcctc acctggataa ccacctgggc tagtcaccag accgttttca cggtagtagt
     2341 tgtaccatga tgaaattcct gcctcggcaa tgataacttc taaaccatcg actcctgtag
     2401 tcgcaagacc attggacatg gtacctagat aggaaagtcc cgttgtagca acttttccgt
     2461 ttgaccaatc agccttgact tgacgctggc gcgtgtgatc agtaaaggca cggcaacggc
     2521 cgttaagcca atcgatgaca tttttataag cctcgatttg ctggtagtct ccattagtca
     2581 tgaaacctgt cgagtctttg gtaccaacac ctgagacata gagattggca aagcctctcg
     2641 gaaggaagta gtcgtttagt gtatagctag agttgatgtg agttagcttt tcctcagcct
     2701 ctgctataag ctcagcttta ccttggggtt ggacgagatt tagttgaggt ttctctagct
     2761 caatcttgtg aggaagttta acctcaagct cgccctccat cttgtagaga gccttgtcac
     2821 tagccttgtc attggttccc tgatgataag ggctggctgt catgatggca gggatttttc
     2881 catcaaaacg agggcgaata atgctaacct ttactaggtc tgatagccct ttttggtcag
     2941 tatcgacacg agactcaacg taaacgactt cacgaatgac atcctggtta gaaaaagtag
     3001 ccaaactctt gccgttaaag tagtggtagt cattatcctc cggaataaga ccatcactaa
     3061 caagttggtc gataagagta tttccttttt tggtgcgagt attgagtaac tgatagagat
     3121 tttcaatcaa gtcaccatat ataatgggaa atccagtttc tttacgaaaa acgtcactat
     3181 cttcgaagtc aaccaaataa gaaaagccta aaagttgaaa agcaacagta taaaaaatat
     3241 ctgctgtcag ttcatcttct gattgaaaaa atgtcagcag gtctgttttt ttatcagctg
     3301 ctaggataga aagtgggtag ttggtgtctt gataagtgaa aaagaaacga cgtaaaaagg
     3361 tttcaagtga gtctttgtga ttggctgtat tttgtaaatc aaagccacat ttttttagtt
     3421 cagataagac attttctttt ggaaaattga tataactata ttgattaaaa cgcatagaac
     3481 ctccatatag aatgacagtt aaggttatta tatcaaaaaa aaagcagaaa gggaattgtt
     3541 aacttcaaaa ggaaataatc caataaaaat gaataaagta ctaaattcaa tatagagaac
     3601 agagtaacaa taagaataaa tagatagggt ataaaagttc taggagattt atattatatg
     3661 ctttctgttt ttatatacaa tatagtataa atataaaaat gatgacaaaa atacaaatga
     3721 atagaaaata aattagtaag ctgatgaaat ttttctcaag agaagccatt tataggtgaa
     3781 aatggtataa tatagtgaga aggatagagg agaagtgtaa attgatcgca caactagata
     3841 caaaaacagt ctatagtttt atggaaagcg tcatttcgat cgaaaagtat gtgagagcag
     3901 ctaaagaata cggctacact catttggcta tgatggatat tgacaatctt tatggcgctt
     3961 tcgactttct agagattaca aaaaaatacg gcattcatcc tttgctaggg cttgaaatga
     4021 cagtgtttgt agatgatcag ggagtgaatt tgcgcttttt agctctatct agtgtgggct
     4081 atcagcagtt gatgaagctt tcgacagcca agatgcaggg ggagaaaact tggtcagtcc
     4141 tgtcccagta cctggaggat atcgcggtca ttgtgcctta ttttgataga gttgagtcgt
     4201 tagaactagg ctgtgattac tatatagggg tttatccaga aacactagca agcgaatttc
     4261 atcatcctat cttacctctt tatcgggtca acgcttttga aagcagggat agagaagttc
     4321 ttcaagtttt aacagcgatt aaagaaaatc taccgctcag agaagttccc ttgcgttcga
     4381 gacaagatgt ctttatatca gcaagttctt tagagaaact attccaagag cgttttccgc
     4441 aagctttgga caatttagaa aagcttattt caggcatttc ttacgacttg gatactagtc
     4501 tgaaactgcc tcgttttaat ccagctagac cagcagtaga ggagttgaga gagcgtgctg
     4561 aactggggct tgttcagaag gggttgacta gtaaagaata tcaagataga ctagaccaag
     4621 aattgtctgt tattcatgat atgggctttg atgattattt cttggttgtt tgggatttgt
     4681 tgcgttttgg acgatcgaat ggctattata tgggaatggg aaggggttct gcagtaggca
     4741 gtttggtttc ttatgcctta gacatcacgg ggattgaccc agtagagaaa aatctgattt
     4801 ttgaacgctt tcttaatcgt gaacgctata ccatgcctga tattgatatt gatatcccag
     4861 atatttatcg tccagatttt atcagatatg ttggtaataa atatggtagt aaacatgcgg
     4921 cacaaatcgt tactttttca acctttggag ccaagcaagc tcttcgagat gtcttgaaac
     4981 gctttggtgt gccagagtat gaattatctg caattactaa gaaaatcagt tttcgtgaca
     5041 atcttaagtc ggcctatgag ggcaatctcc agtttcgtca gcaaatcaat agtaagttag
     5101 aataccaaaa agcttttgag attgcttgca agatagaggg ctatccaagg caaacctctg
     5161 tccatgcggc tggtgttgta attagtgacc aagatttaac caactacatt cctctaaagt
     5221 atggtgatga aattccactg actcagtatg atgctcatgg agttgaggct agcggacttt
     5281 tgaagatgga ctttctggga ctacgaaatt tgacctttgt ccagaagatg caagagttgc
     5341 ttgctgaaac agaaggtatt catctgaaaa ttgaagaaat cgatttagaa gacaaagaaa
     5401 cattagcttt atttgcctct ggtaatacaa aaggtatctt tcaatttgag caaccaggtg
     5461 ccattcgtct gcttaagcgt gtgcaaccag tctgttttga agatgtcgtc gcgactactt
     5521 ctctaaatcg accgggtgct agtgactata tcaataattt tgtggcaaga aagcatgggc
     5581 aggaagaagt gactgttctg gatccagtac tggaggatat tttggctcca acctacggca
     5641 taatgctcta tcaggagcag gttatgcagg ttgcccagcg acttgccgga tttagtcttg
     5701 ggaaagccga tattttgcgt cgggctatgg ggaaaaagga tgcctctgcc atgcatgaga
     5761 tgagggcttc ctttattcaa ggttcattag aagctggtca tactgtggaa aaagcagagc
     5821 aggtctttga tgttatggag aagtttgcag gttatggttt taacaggtca cacgcctatg
     5881 cctactcagc cttggccttc cagttggctt atttcaaaac gcattatcca gccatttttt
     5941 atcaggtcat gttaaattct tccaacagtg attacttaat agatgcactt gaagcaggtt
     6001 ttgaagtagc ctctctatcc atcaacacca ttccctatca cgataaaatt gccaacaagg
     6061 ccatctatct aggtttgaaa tccattaaag gagtcagtaa tgatttagct ctctggatta
     6121 ttgaaaatag accttattct aacattgaag attttatagc taaattacct gagaattatc
     6181 tgaaacttcc tctgctagaa cctttggtaa aagttggtct tttcgattca tttgaaaaaa
     6241 atcgtcaaaa agtatttaat aacttagcta atctatttga atttgtgaaa gagttgggaa
     6301 gtttgtttgg agatgctatt tatagttggc aggaatcgga agattggacg gaacaagaaa
     6361 aattttatat ggaacaagag cttttaggga taggtgtcag caaacatcca ctacaagcta
     6421 ttgcaagtaa ggctatttac ccgattaccc caatcggaaa tttgtcagaa aatagctatg
     6481 ctattatctt ggttgaagtt cagaaaataa aagtgattcg taccaaaaag ggtgaaaata
     6541 tggccttctt acaggcagat gatagtaaga aaaaattgga tgttacactc ttctcagatt
     6601 tatatcgaca ggttggtcag gaagtaagag aaggagcatt ctactatatc aaagggaaag
     6661 tccaatcacg tgacggtcgt ctgcaaatga ttgcacaaga aataagagaa gcagttgctg
     6721 aacgcttttg gatacaggtg aaaaatcatg aatcggatca agaaatttca cgtattttag
     6781 aacaatttaa aggcccaatc ccagtcatca tccggtatga agaggaacag aaaaccatcg
     6841 tttctcccca tcattttgta gctaaatctg atgaattaga ggcgaaattg aatgaaatcg
     6901 ttatgaaaac gatttatcgc taaaaatacg gaaaatagaa gaattttaaa atcaaatgtg
     6961 atataatcaa gaagaatgtt aaaagaaaaa ggagcataac caatatgaaa cgtattgctg
     7021 ttttgactag tggtggagac gcccctggta tgaacgctgc catccgtgca gttgttcgtc
     7081 aagcaatttc agaaggaatg gaagtgtttg gtatctatga cggatatgct ggtatggttg
     7141 ccggtgaaat tcatccccta gatgcagctt cagtagggga catcatttct cgtggtggta
     7201 ctttccttca ctcagctcgt tacccagagt tcgctcaact tgaagggcaa cttaaaggga
     7261 ttgagcaatt gaaaaaacac ggaattgaag gtgtagttgt tatcggtggt gacggatctt
     7321 accacggcgc tatgcgtttg actgaacatg gcttcccagc tattggtctt ccaggtacaa
     7381 tcgataacga tatcgttggt actgacttta caatcggttt tgacacagcg gttactactg
     7441 ccatggacgc tatcgataag attcgtgata catcatcaag tcaccgtcgt acttttgtaa
     7501 tcgaagttat gggacgtaac gctggtgata tcgctctttg ggctggtatt gcaactggtg
     7561 ctgatgaaat catcatccct gaagcaggct tcaagatgga agatatcgta gcaagcatca
     7621 aagctggtta tgaatgtggt aaaaaacaca atatcatcgt cttagctgaa ggtgtgatgt
     7681 cagcggctga atttggtcaa aaacttaaag aagctggaga tacaagcgac cttcgtgtaa
     7741 cagaacttgg acatattcaa cgtggtggtt ctccaactgc gcgtgaccgt gttttggcgt
     7801 cacgtatggg tgcacatgct gttaaacttc ttaaagaagg tatcggtggt gttgcggttg
     7861 gtattcgtaa cgaaaaaatg gttgaaaatc caattcttgg tactgcagaa gaaggggcat
     7921 tgtttagcct tactgcagaa ggtaagattg tggttaacaa cccgcacaaa gccgatattg
     7981 agctatctag cttgaataag agcttgtcat aatttacaat ttagttaata agaccaaaaa
     8041 ggtcatatat aaaggagtca caaaaatcat gaacaaacgt gtaaagatcg ttgcaacttt
     8101 gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt gaggacggat actggggtga
     8161 aaaacttgat gttgaagctt cagctaaaaa cattgctaaa ttgattgaag ctggtgctaa
     8221 cacattccga ttcaacttct cacacggcga ccaccaagaa caaggtgagc gtatggcaac
     8281 tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg atacaaaagg
     8341 acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa gaatattcat acaaaactgg
     8401 tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag tgattgcgtt
     8461 gaacgttgct ggtgctcttg atatctatga tgatgttgaa gttggtcgtc aagttttggt
     8521 tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc gtgaatttga
     8581 agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca tccctaacac
     8641 taaaattcct ttcccagctc ttgctgaacg cgataacgac gatatccgtt tcggtcttga
     8701 acaaggtatc aacttcatcg caatttcatt cgtacgtact gcaaaagatg tgaacgaagt
     8761 tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa ttattcgcta aaatcgaaaa
     8821 ccaacaaggt atcgataact tagacgaaat catcgaagca gctgatggta ttatgattgc
     8881 tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc aaaaaatgat
     8941 tatcaagaaa gtcaatgctg caggtaaagt tgttatcact gcaacaaaca tgcttgaaac
     9001 aatgactgaa aaaccacgtg caactcgttc agaagtatca gacgtattca acgctgttat
     9061 cgacggaact gacgctacaa tgctgtcagg cgagtctgca aacggtaaat acccactcga
     9121 gtcagtaact acaatggcta caatcgacaa gaatgctcaa gctcttctta atgaatacgg
     9181 acgtcttgat tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg cttctgctgt
     9241 taaagatgct actagctcaa tggatatcaa attggtcgta actcttacta agacaggtca
     9301 tactgcacgt ttgatttcta aataccgtcc aaatgctgac atcttagcat tgacatttga
     9361 cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt tgacagatgc
     9421 tccatcttca actgacgata tgttcgaaat cgctgaacgt aaagcggtag aagcaggtct
     9481 cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag aagctgttcg
     9541 cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc tatcatatcc
     9601 agctttagag cttgtgtgat aggctttttg tatagagggt aagaaatagg caaaactttc
     9661 ataatggatt gatactcttc gaaaatcaaa ttcaaaccac gtcagcgtcg ccttaccgta
     9721 tatatgttac tgacttcgtc agttctatct acaacctcaa agcagtgctt tgagcaacct
     9781 gcggctagct tcctagtttg ctctttgatt ttcattgagt atgaaataag atatgcacaa
     9841 attgattagg aaattcaaat gaatttctac aaatgtttta gcaatcgtaa tgtacttgtc
     9901 tagattcgat ctgatatatt ttcgatttaa tgatatggta tttaaaacct ccaaagtagc
     9961 ttgctccatt cttttactta cgtgagtgta gatgttattt actgttttag cgtttttgtg
    10021 ttccactcta accattatag cattcttctc agctagtgta ctaaggagtg tgtgcctgaa
    10081 aatatgggaa ctaaggggct ggtttatcgg tttctctagt ttagtatttg ccttttgcaa
    10141 agtgatgtta aatgcctttc tctaaattta catatcacta ttgtttaaca aaatctaatc
    10201 tactttaggt cacttattct ttttttgaaa tgtagaatga actttttcaa agtttttcga
    10261 atcttttaaa atctgtttgt tttatatcgc cattctcccc cttttttaat tctccctata
    10321 tagcctgaca actttcccga tggtacgaat atggttgctt tcgtctaggt ggatgtcggg
    10381 gtatttggga ttgagttttt ttaaggtagc cttggcggag tttcttgaca tagttagcgc
    10441 cgtctacttg gaagatgccg atggtattat agtcaatctg tggggtattc ttgataaata
    10501 ggtagtcgct gtttcttatc tttggctcca tggacttgct gacgacataa gcgattgggt
    10561 cgtagtcgtc tgggataatg gaaactccat aactaaatcg tcgtcctgca tcgagcggct
    10621 acctgcagag ataaactacc taacacgaga gtaagtagtc tgtctgtagt cgtccagtct
    10681 gatgattttt acgatatttc gtttttctgc tcatacagtt gcctctcggc ataggtcaga
    10741 actttacctt gtctgggtgg tgcccgttgg tcgtagatag attggatatc gctaggagaa
    10801 tccttttgaa ctggaggaaa gagggtatca atcaagctac tgaatacttt agctaagtca
    10861 aatatagtat ttttcttagt agacctaacc cttttttcat aatttccaat ggtgttttta
    10921 cttataccaa tcttagtacc caattcttat tgagtccaac cattactagt ctatattgtt
    10981 ttatagttga ttgagtttgg aatagtacgc tgtagctgct aaaacatttc taggaattaa
    11041 tttgactttc ctaatagagt tgttcatatc ttatttcaat ctactatgtt tttcacctct
    11101 aacaatcgca atctcttctt tatccatgaa tgaaatcgct ttctattttt gtaagtaaag
    11161 catcacacga aatccacgaa aatgaaaacc tttgttgtgt tttcgtaaaa aatttgttga
    11221 cagagcacga aacgcctact ataattaaat caagcttaag gaaataacaa aaaaacaaat
    11281 cggagggaaa gacgatgaac acattaaatg agaaagtaat caatatctgt aaagcagtag
    11341 ttaaagaaac tttaatccaa gacatttagg agaaagaaat gaagaaatca agaaaattag
    11401 ccacattagg aatctgttca gccttgtttt taggcttggc tgcttgtcaa caacaacatg
    11461 ctacttctga ggggacgaat caaaggcaaa gcagttcagc gaaagttcca tggaaagctt
    11521 catacaccaa cctaaacaac caggtaagta cagaagaggt caaatctctc ttatcagctc
    11581 acttggatcc aaatagtgtt gatgcatttt ttaatctcgt taatgactat aataccattg
    11641 tcggctcaac tggcttatca ggagatttca cttcctttac tcacaccgaa tacgatgttg
    11701 agaaaatcag tcatctctgg aatcaaaaga agggcgattt cgttgggacc aactgccgta
    11761 tcaatagtta ttgtcttttg aaaaattcag tcaccattcc aaagcttgaa aagaatgacc
    11821 aattgctttt cctagataac gatgcgattg ataaaggaaa ggtctttgat tcacaagata
    11881 aggaagagtt tgatattcta ttttcgagag ttccaactga ggcaactaca gatgtcaagg
    11941 ttcacgctga aaagatggaa acattcttct cacaatttca attcaatgaa aaagctcgaa
    12001 tgctgtctgt agtcttgcac gacaatctgg atggcgagta tctgtttgta ggccatgttg
    12061 gggtcttagt acctgctgat gacggtttct tatttgtaga gaaattgact ttcgaagagc
    12121 cctaccaagc gattaaattt gctagtaagg aagattgcta caagtatttg ggcaccaagt
    12181 atgcggatta tacaggcgag ggactggcta agccttttat catggataat gataagtggg
    12241 ttaaacttta atagtgttat gatatgacag taatcttagg atttttattt ctatttttga
    12301 tgacttggtg ggttatttca atcgttaata gccagaaacc acgcaaaaat gaaacattta
    12361 ttggctatat ccaaagatac gatattgatg ggaatggcta tcaatcatta ccgtgtcctc
    12421 agaactgaga ggagttcttg aaaccgtaaa accgctttga acaagagtta cttcaaccca
    12481 ttggctccga cggagtaagt tgctttcgtg aataccaaaa tcagccgcaa tttgttcata
    12541 agttcgatat tctcgcacat attgaagagt ggccataaga aggtcttcta ggcttaattt
    12601 aggttttcgt ccaccttttg cgtgtttaag ttgataagct gtttttaata cagctaacat
    12661 ctcttcaaaa gtggtacgct gaacaccaac aagacgctta aatcgtgcat cagttagttg
    12721 tttacttgct tcataattca tagaactact ataccatatt ttgtttcgca ggaagtctaa
    12781 tgctaaaatc ttatcagtga gaagatttct taaagtttat tctttgtagt ttcatctgta
    12841 ttagtacata atttaactta gagaaaatag gaggactaat cgaatggaat taaaagattt
    12901 tacagaaaaa gaacaggaaa tgattaagaa aaggcttaca atgtctaata ttagtgacaa
    12961 agaaactact gagaagattc tggcgctagt cccacaagac ttgattaagc gaatcccgtt
    13021 ttttgtcaga aaacatgcta caacacgtac gattaaacgt atttcaattg aataccctga
    13081 actctacgct gtagctcaaa caagtggtga gattccagaa aaaaacgcga agaattgcgt
    13141 cagattatca caactatctt tgaacaaaag atgaataagc atagtattaa gtagagaatg
    13201 aaaaaatatt ttattggcgg tttgggaagc aatgcctatc atagcaagga ttttcttcaa
    13261 gaactagatt cgcaggtcta ttttctaaat ccatatgaaa agcatcttcg agatgaaaca
    13321 gaattgaaat catggtttaa aaatgagatt gtagaggaag aatctatctg tctgataggt
    13381 cattctattg gaggcgattt agctcgttat ttcgcatcgg aatttgaaga agtaaagaaa
    13441 ctgattcttt tggatggtgg ctatctagat ttagataaga ttttaccttt ggatacagag
    13501 ttagaggaaa ctaaaaatta tatcaaatct caaattattt cggacttaga tgttcttact
    13561 tctaaagaaa aatctgaagc aaagcattgg tcagaaaata tggagaaagc tgtaagacag
    13621 tcctatcact ggaatgttga gtataataga tatgagttgg ctataaatta tgaaaatata
    13681 gaagcgatac tccgcctacg gagaaaaata caagctttta agagagaagt gggagatacc
    13741 ttgtttatta gtcctcgcta tcctaatgaa gctacatgga gagaggaagc cctaaaagaa
    13801 ttgccagact attttgatac tattttttta gaaaactttg gccatgagct ttatactcaa
    13861 gcacctaaag aaatcgctag tctaatgaat gagtggctcg cttattttct atgagctact
    13921 tgtattgctg gaaatggtat aagatgaaaa tctacaagtc actaattttc atataacaaa
    13981 aaacgaacag gctctttttc tgttattcag aagagaactt gttcgttttt atcttgattt
    14041 tcttaaaaag ctctatatac atagggattt tctggtttat cgactttggt aaagctgtcg
    14101 atttccaagg ttggaaggtt ttgtttgagt tctttatggt agtgattgac cagttttcct
    14161 ttggctgtta tccaagtgtt gttttcatac tgccgggtat tgcccttggt cagcaatcca
    14221 tagacaccag aatctgcgat acagtggata atgccgaatc ggaacagaaa ttgactattg
    14281 gcatgactgg ggtcgttata gacaaagcct gtaaactgga ttgtcttgcc ctcaaactca
    14341 tctggatagt cgtagatagc ctccatgact tccatatagt tttcattagt gatctgaata
    14401 ctatcttggg ataagtattt atccgccgcc gttcgcattt ccttttcata ggctgatttt
    14461 gaaaaataag aactggtatc tggtttcaaa tattggcttg tcgtcccttc gcttgtctga
    14521 atggctagat ctgttccttc cgataggggg aaatgataac ctttagcaga aacggtctga
    14581 gaatccaagc taacagttgg gaaagttaag ccgatgacaa gtggaatagc cagaagagaa
    14641 atactcgtca tcttggccaa tcggctgttc agatgactgt gggttttgac ttgcttcatc
    14701 cagatataca attgaacaat tgccaagata aaggaaagca ccatggagat ataggccaga
    14761 taggaatagt gcatgttgat gtactggttt agtttgcccg acagatggag gtaaatagtc
    14821 agttcaaaat agccagctaa aactaaaaat cgaatcatag gatgactcca atcaagagag
    14881 aatagactaa gacgacaaga gttacaatcg ttatgaagtg actgataaat cgtgctttca
    14941 agtaattttt catcatgaga atatttttga tatccagcat tggaccaatg acgagaaagg
    15001 ccagaactgg tgccaaaccg aaactcgaga gaagagaagc acctataaag gcatccgcct
    15061 cactacagag cgaaagaaga aaggccaaaa tcatcaagag caggatggca aaaagaggag
    15121 tcgcactgat agaggtcaga atccgagtcg gaacgtagac ctgtattata gaagcaaaga
    15181 ggcagccaaa taccaaataa cgccccgtat caaaaaattc atcaatggcc tgcacaaaga
    15241 cttgaaaaac tttttttgca gaactcaagt aagaaaaatc atgctcatga caagccagac
    15301 gattttcttt ctgaatcggt tcttgccaga aaaatcctag aaaaattcct agtattacag
    15361 ccacaagaat ggaacccaga gctcgtaata gggcgacatg gaaggagttg ccaaaggcag
    15421 aataggtcgc aaaaagaaca atgggattga taacaggtgc tgtcacaaga aaaggaacgg
    15481 ctgtgtaact gggaaccttt ttttccagaa aacgattgat gatggggacg attccacatt
    15541 cacaagaagg gaaaagcata ccgacaaagg tcccaaaaaa gattctcccc caacgatttc
    15601 gagggagaaa atgataaacc ttgtcaggtg tgatataaac ttcaatcagc cctgagacaa
    15661 tgcttcctat tagaacgaag ggaagggctt caatgataat ggagagaaaa atggctccag
    15721 tttgaagtac actagatggg agttgttgaa aagcagtcat ctagtttttc ttttctgctt
    15781 tggctttttt ctctttgtca tcagggaaag taacttgttt caaatcaggg agtttagcaa
    15841 actcttcaaa catcttgtcc aagtcgtctc gttttgtaaa ttttacagcc ataggtgtac
    15901 ctcgattcta aagtctacct ctattatact attattttgc ggaaaaggga gttttttaat
    15961 ttgttttcga tagttgatac acttcgaaaa tctcttcaaa ccacgtcagc ttcgccttac
    16021 cgtatatatg tgacttatcc acaacctcaa aacagtattt tgagcagcct gcggctagct
    16081 tcctagtttg ctttttgatt ttcattgagt atgaaaagga ttggagaaag ccttccagct
    16141 tgtggtataa tagatttatg gataaaaaat atgaaaaaat ctctcaggat ttgggagtga
    16201 tgttaaagca aattgatacc gttctaagtt tgacagctga aggggcgact attcccttta
    16261 tcgcgcgtta tcgcaaggac atgactggta gtctggatga ggtggcgatt aaggctatta
    16321 ttgatttgga taaaagtctg acaaatctca atgaccgtaa ggaagctgtc ttagctaaga
    16381 ttcaagaaca aggtaagttg accaaggaat tggaagaagc tatcttagtt gccgaaaaat
    16441 tagcagacgt tgaagaactc tatcttcctt ataaggaaaa gcgtcgtacc aaggcaacca
    16501 ttgcccgtga agctggactc tttcctcttg ctcgtttgat tttgcagaat atagttgact
    16561 tagagaaaga agctgaaaag ttcgtctgtg aaggatttgc gactggcaag gaagccttga
    16621 ccggtgcagt tgatattttg gtcgaagcct tatcggaaga tgtgaccttg cgttctatga
    16681 cttatcagga agtgctgaga cactctaaac ttacttctca agccaaggat gaaagtcttg
    16741 atgaaaagca ggtttttcag atttattatg atttttcaga gacagttgga actatgcaag
    16801 gctatcgtac cttggctctc aatcgtgggg agaaacttgg tgtcttgaag atcggttttg
    16861 aacatgcgac ggaccgtatt cttgccttct ttgctactcg tttcaaggtg aaaaatgctt
    16921 atattgatga agttgttcag caatccgtta agaaaaaggt cttgcctgct atcgagcgtc
    16981 gtattcggac agaattaact gagaaagctg aagaaggagc tatccaactt ttttctgaca
    17041 atctgcgcaa tctcctcttg gttgctccac tgaaagggcg cgtggttctt ggatttgacc
    17101 cagcctttcg tacaggtgcc aagttagctg tcgtggatgc aacaggaaaa atgctgacaa
    17161 ctcaggttat ttatcctgtt aaaccagcat cagctcgtca aatcgaagaa gccaagaaag
    17221 atttagcaga tttaattggt caatacggtg tagagattat tgccattgga aatggaacgg
    17281 ccagtcgtga aagtgaagct tttgtagcgg aagttctgaa agatttccct gaagtcagct
    17341 atgttatcgt taatgaaagt ggtgcttctg tctattctgc cagcgaactt gctcgtcagg
    17401 agtttccaga cttgaccgtt gaaaaacgct ctgccatttc tatcgcccgt cgtttgcaag
    17461 atcctcttgc ggaattggtc aaaatcgatc ctaagtcaat tggtgtcggt caataccaac
    17521 acgatgtcag tcagaagaaa ctatctgaga gtctggactt tgttgtcgat acagtggtta
    17581 accaagttgg tgtcaatgtc aatacagcta gcccagctct tctttcacac gtagctggac
    17641 tcaacaaaac tatctctgaa aatattgtca aataccgcga ggaagaagga aaaatcactt
    17701 cacgcgccca aatcaagaaa gttcctcgtc tgggagccaa ggcctttgag caggctgctg
    17761 gtttccttcg tatccctgaa agtagcaata tccttgataa tacaggagtt cacccagaga
    17821 attacactgc agttaaggaa ctcttcaaac gtttagatat taaagaccta aacgaagaag
    17881 cccaaagcaa actcaagtcc ctttcagtca aggaaatggc tcaagagcta gacctcggtc
    17941 cagaaaccct taaagatatc attgcagatc ttctcaaacc aggtcgagat ttccgtgatt
    18001 cctttgacgc acctgtgctt cgccaagatg tcctagatat caaagaccta gtggtaggtc
    18061 agaagctaga aggtgttgtg cgtaacgttg ttgacttcgg tgccttcgtt gatatcggga
    18121 ttcacgagga cggcttgatt catatttctc atatgagtcg caagtttatc aaacacccta
    18181 gtcaagtggt gtcagttgga gatttggtga ccgtttgggt caagaaaatt gatactgaac
    18241 gtgaaaaagt taatctgtcg ctcctcgctc caaatgaaac tgactgatta tgtcaagcag
    18301 gtttcactag aagacttcgg gagagctttt atccatcatg tccagtggaa taggcgtcta
    18361 cgttcgacag gtgggcgatt tttccccaaa gatgggcatc tggattttaa tcccaaggtt
    18421 tatcagaaac tgggtatgga ggtttttagg aaaattgtcc gacatgaact ctgtcattat
    18481 cacctttatt tccaagggaa gggctatcaa cacaaggatc gggattttaa ggaactgttg
    18541 aaagcagtgg atggattaag gtttgtacca tccttgccca atagtaactc taaaccactc
    18601 aagctttatc gttgtcaatc ctgccagcaa aggtatcagc gcaagcgtag gattgatacc
    18661 aaacgctatc gctgtggact ttgtcgaggt aaattgcttc tgataaatca gcctgaggac
    18721 tgatgaaagc cgagcctccc cgtgatatac tatgtctaac ctagcagaaa gaggaaatat
    18781 catgaacagt aaattttata aaatgagacg caatcgcatg atttcaggag ttctggcagg
    18841 tctgtcagac aagtggaatt ttgatgttac cctagttcgt ttcttgtttg ccatttttac
    18901 agttgcaaac tttggacttg gcgtgattat ctatatcatc ctagcttcta tcatgcctac
    18961 caaggaagaa atcgaagcag aaatgtacgg aacaggccca cgtaaacgca aagaagccca
    19021 agccattgac gacaatgaag gctggttttg gtgaggttct acagaagatt tggaataagc
    19081 aaaaagcttt aaatcaatag tctaaactgc ttgatttaaa gcttttttac ttttatactc
    19141 aataaaaatc aaagtgcaaa ctaggaagcc agccacaggc tgtaatttag tcggcaatgt
    19201 gaagttgaca tagtttgcac tttgattttt gaatagtatt aataatattt cgccagcttc
    19261 atccacaaac tatagtggat tggaactaga atagtacacc tctacttcta aaacattgtt
    19321 agaaatcgat ttgactatcc tgatcgattt gtcctgttct tatttcattt tattataaaa
    19381 gcagtaattt aaactcagtt ttttaatcta tttttgctgc tgagacaata catttttgga
    19441 aaaatggtgg atgctgataa caactgataa ccagcaaata acataagcag tgccggtaaa
    19501 ttctgtaccg ataaagtgtg tgtgttcaac taagagctga ccgatgaatg gagagagcag
    19561 atagagaagt ccgatgagta tatgttcttt gtgtttcatt aaagcgcacc ttctttcctt
    19621 ataggttgaa cgacttgcaa gtgttaaatt gaatggtatg ttatctaggt aagcttactc
    19681 aaatgatagt tcccgcttcc tcctttccaa agtaagcctt ttcatactta tattttacaa
    19741 ctttaaaaat aggaaatcaa atcattttct aagtaatttt gcttatattt cacccaatct
    19801 tacaaaaatg taagattaaa gtctcttttg taaggttagg ttatggcaag cggtcttttt
    19861 ttgatgtaaa ctagactcat aaagaacaaa ggagtaacat catgaaacaa atcttacata
    19921 agaaaactag aaaaccaagt cacaaagaaa ttgagcgcgt tcagctggga tgcactatga
    19981 tgcaagctac atttcatttg atgggatatt aagaaaggag attctcatga cacttttaga
    20041 tgtaaaacac gttcaaaaaa tttataaaac acgttttcag ggcaaccaag tagaagccct
    20101 caaggatatt cactttaccg tcgaaaaggg tgactacgtt gccatcatgg gtgagtctgg
    20161 ttctggtaaa tcaactcttc tcaatattct agctatgctg gataaaccaa gtcgtggtca
    20221 ggtttacttg aatggaactg acaccgcaac cattaaaaat tcacaggcct ctagcttccg
    20281 tcgtgaaaag ttgggctttg tcttccaaga ctttaacttg ctagatactc tatctgtaaa
    20341 ggacaatatc ttgcttccgc ttgtcttgtc aagaagacct attacagaga tgatgaagaa
    20401 attggtggtg acagctgaga atctgggaat aaaccaatta caagagaagt acccttacga
    20461 gatttctggt ggccagaaac agcgtgtagc agtagcacgc gccatcatca ctgaacctga
    20521 aattctcctt gcggacgaac cgacaggagc tcttgactcc aagtcatctg cagccttact
    20581 tgatgtcttt gatgaaatca atgagcgcgg ccaaaccatt ctcatggtaa cccactcaac
    20641 agcagcagct agcagagcta aacgtgtact ctttatcaaa gacggcattc tttacaatca
    20701 aatctaccgt ggagagaaga cagaacgtca gatgttccaa gaaatctctg ataccttgac
    20761 tgtcatggca agcgaggtga attagtatgt ttcgattaac caataagtta gcggtatcga
    20821 acttgattaa aaaccgcaaa ctctactatc cttttgcgct ggctgttctc ttggcagtca
    20881 ctgtcaccta tctcttttac tctctaacct tcaatcccaa gattgctgaa attcgtggag
    20941 gaacaaccat tcaggctaca cttggatttg gtatgtttgt cgtcaccctt gcgtcagcca
    21001 ttatcgttct ctatgccaat agttttgtca tgaagaaccg ttccaaggaa ctaggaattt
    21061 atggcatgtt gggcttggag aagcgtcatc ttatcagtat gacctttaag gagttagtgg
    21121 tatttgggat tctaactgtt ggagcgggta tcggtattgg agccttgttt gacaagttaa
    21181 ttttcgcttt cctgctcaaa ctaatgaaat tgaaggttga gctggttgct accttccaga
    21241 cgaaagttgt cattacagtg cttgttgtct tcggtttgat tttcctaggc ctcatgttcc
    21301 tgaatgccct tcgaatcgcc cgtatgaatg ccctccagct ctctcgtgag aaagctagtg
    21361 gagagaaaaa aggtcgcttc cttcctctcc aaaccattct tggttccata agtttaggaa
    21421 ttggctatta tcttgccctt acggtaaaag atcctcttac agccttaaca accttcttca
    21481 tagctgtttt actggttatc tttgggactt atctcttgtt taatgcaggg attaccgttt
    21541 tcctccaaat cttaaagaaa aataagaaat actattacca accaaataat ctcatatctg
    21601 tttctaactt gattttccgt atgaagaaaa atgcagttgg actagccacc atcgctatct
    21661 tgtcaacaat ggttttggta accatgtcag cagcgacaag cattttcaat tcctcagaaa
    21721 gctttaaaaa agttctaaat cctcatgatt ttggggtttc agggcaaaat gttgaaaaag
    21781 aagacttgga caaactcttg agccagtttg caagtgacaa aggttatagt gtcaaagaga
    21841 aagaagtact tcgttacagt aactttggta ttgcaaatca agaaggaact aagttaacta
    21901 tttttgaaaa aggacaaaac cgtgtccaac caaaaacagt tttcatggta tttgaccaaa
    21961 aagattatga aaatatgact ggtcaaaaac tgtctctatc aggaaatgag gtcggactct
    22021 ttgcaaagaa tgagggagtt aaagaacaga aagctctaac tctaaatgat catcaatttt
    22081 ctgtaaaaga agaatttact aaagatttta ttgtcaacca tgttccaaat cagtttaata
    22141 ttttgactgc tgattacaat taccttgttg tacctgattt acaagccttt ttggatcaat
    22201 tcccagattc ggctatctat aatcagtttt acggtggtat gaatgtaaat gccagtgaag
    22261 cagaacaact caaggtcgct gaggagtatg aaaaatactt acaaaagttt aatgctcaat
    22321 taaacactga aggtaactat gtgtatggta gcactctagc agatgctagt gctcagatga
    22381 gtgccctctt tggtggtgtc ttctttatcg gtattttctt atccattatc tttatggtcg
    22441 gaaccgttct ggtcatctac tacaaacaaa tttctgaagg atatgaagac cgtgagcgct
    22501 ttattatctt gcagaaagtc ggtttagatc aaaagcaaat caagcaaacc atcaacaaac
    22561 aggttttaac tgtattcttc cttcctttgc tctttgcctt cctacatcta gcctttgcct
    22621 accatatgct tagtctgatt ttaaaagtga ttggtgtact ggatacgact atgatgttga
    22681 ttgtgacctt gtctatctgc gctatcttcc tcatcgccta tgtgctgatt ttcatgatta
    22741 cttcaagaag ttatcgcaag attgtgcaaa tgtaaaaaag atacctcgac ttcaaaatcg
    22801 aggtatttct tgtattctaa atgctgaaaa gttgttcgag caggaaggta actcccatgg
    22861 tcaagagacc aatagcaagg ttccgaatca tagctgtttt ggttggggct tttccaagtc
    22921 tagcacttgt gtaaccagtg agaagaaggg ccacaccgac aataaggacg gtagcaggga
    22981 tgcggtaatc acttggaaaa atggtcactg acagcattgg aggcaaactt ctaaggaaaa
    23041 aggcaacgaa gctagaaatg gcagcgtgcc aaggattggt aaattcttca tactcaatcc
    23101 catatttttc ctctaccaga gccttgagtg gatttttaag aaagatctta ttagtcaaga
    23161 gttgggcaga agttttgaat tcttcatttt ggatataagc agcatagagg gattttttgg
    23221 ctagttccct atcttggtct agcaagagtt tttctcgcga aacggcagct tcctcggtat
    23281 cttttggagt tgaaacggat acatattctc caccagccat tgaaaaggca ccagctaaga
    23341 tagccgcaaa tcctgataaa aagataatcc agatattggt cgtggcactg gcaaccccga
    23401 taaccacacc agcaatggaa ataattccat cgttagcatc aagaacaccc gcacgcagga
    23461 tatttaaacg acctgcaaaa tttgaatcaa tttcgtgatt tgtttctgac gctaaatttc
    23521 aagttcaagt tagccatcca
//
LOCUS       DAVAZV010000031        23312 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVAZV010000031 DAVAZV010000000
VERSION     DAVAZV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.031"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(196..654)
                     /locus_tag="VQT46_001210"
     CDS             complement(196..654)
                     /locus_tag="VQT46_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET2371243.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(651..1091)
                     /locus_tag="VQT46_001211"
     CDS             complement(651..1091)
                     /locus_tag="VQT46_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2371244.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1675..2541
                     /locus_tag="VQT46_001212"
     CDS             1675..2541
                     /locus_tag="VQT46_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371245.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEKVEELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKIYMEWIKSLIDFYFYGQKEDAIVRLEGVLSQLSVSDLNYLQVSNTLFN
                     FYYDIGDLGRFNKIREKLEYQVNHLNLSTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKAYRTNYLLADLYLLMGNVSENFSSKSSVKEYFETAYFLYKLEENMSMT
                     LKVEHYIADITE"
     gene            2878..3435
                     /locus_tag="VQT46_001213"
     CDS             2878..3435
                     /locus_tag="VQT46_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase family
                     flavoprotein"
                     /protein_id="HET2371246.1"
                     /translation="MDKKNLLVLVTGSVGASNVDTYLYYIKKFYNVKVILSENSKKFI
                     SKELISYFCDKVYDEIFVEEVVPHVFLPYESDLLLILPATANVIGKIANGIADDLVTA
                     TVLNFNKKIIFCPNMNSTMWDNHIVQRNVSILKELGHIFLFESKKTYEVGLRKAIDST
                     CSMLQPQSLVKELIKLENIVLEEGH"
     gene            3656..4762
                     /locus_tag="VQT46_001214"
     CDS             3656..4762
                     /locus_tag="VQT46_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HET2371247.1"
                     /translation="MINKKIQQVVLESLQNFLNGNFISPCVVYDFGLLETVLDEFKNQ
                     IPVTFNYQLFYAVKANSNEKILEFLVDKIDGVDVASLSELDVAKKFFPPTQISVNGPA
                     FSYETLYNLIKKQYKVDINFLEHLQQFSPKESVGIRVTEPDELNNRMSRFGINICSDN
                     WTSNLQNPLITRLHFHFGEKDDKFIVKLDKILFKLQEINKLREVREINLGGGFMKLFM
                     ENRLKEFFLSLMEIYKKYDIDSTVTTIIEPGSAITSFSAYMITSPVNVSEVNEQQVIT
                     LDTSIYTNTLWFVPHIITTLNSSSKERYSTILYGNTCYEHDKYKMKVSLPRLTQNSSI
                     VFFPVGAYIKSNHSNLHRNDFMREVYLWTKNLTY"
     gene            4738..6129
                     /locus_tag="VQT46_001215"
     CDS             4738..6129
                     /locus_tag="VQT46_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371248.1"
                     /translation="MDKKLDILDKVKEYLGNKTTQILDNQYKEFLKLNDIRRAFGISE
                     KVLNNSFNFTSKEFNDLINNENYLFEYACRIREEWRKKCFNHSYRFLCSPIITDDFLN
                     TKTLRSSQIEYKYERYLSKSSIGDRAVDGFVSFNTLTANGMSAIKLCLEILNSIFFKK
                     KIDLLYSTGYYETRFLLNNLAKSGISCYEVSNCELDKDKFYNVFMMEPNRADLTLQKT
                     DFKIVEYFVKYKNNSIKVVILDISYQGSNFKLVEFLEKFKFANVIIFVVRSLIKLDQM
                     GLELTNGGIIEVFIPNHLRKLKNFIEEEFNKFRNSHGANLSLYEYCLLDNSLTLKNDW
                     NYSDLVMKFTSNFYADIKDLFMENSDIEIIHEEGVPFVFLDLIGEGKKEYEMFFQWLN
                     FFYKQLGITLYARNSFGFRNLTVEYFGIIGTERYIFKICPGVYKGLSYYLMKFLLKSF
                     SNEYLKTTDEVNR"
     gene            6126..7304
                     /locus_tag="VQT46_001216"
     CDS             6126..7304
                     /locus_tag="VQT46_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2371249.1"
                     /translation="MKNLIKLLIIRLIVNLADSVFYIVALWHVSNNYSSSMFLGIFIA
                     VNYLPDLLLIFFGPVIDRVNPQKILIISILVQLAVAVIFLLLLNQISFWVIMSLVFIS
                     VMASSISYVIEDVLIPQVVEYDKIVFANSLFSISYKVLDSIFNSFASFLQVAVGFILL
                     VKIDIGIFLLALFILLLLKFRTSNANIENFSFKYYKREVLQGTKFILNNKLLFKTSIS
                     LTLINFFYSFQTVVVPIFSIRYFDGPIFYGIFLTIAGLGGILGNMLAPIVIKYLKSNQ
                     IVGVFLFLNGSSWLVAIVIKDYTLSLILFFVCFMSKGVFNIIFNSLYQQIPPHQLLGR
                     VNTTIDSIISFGMPIGSLVAGTLIDLNIELVLIAISIPYFLFSYIFYTDNGLKEFSIY
                     "
     gene            7729..7962
                     /locus_tag="VQT46_001217"
     CDS             7729..7962
                     /locus_tag="VQT46_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000623387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2371250.1"
                     /translation="MISIDLGGTNIKITVLSNDGEIETLWSITTDTSEKGSQIISDII
                     SSIKNKLTERNIPDSDLLGIGMGSCSSYFPCKS"
     gene            8245..10194
                     /gene="mutL"
                     /locus_tag="VQT46_001218"
     CDS             8245..10194
                     /gene="mutL"
                     /locus_tag="VQT46_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET2371251.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKIQITDNGYGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(10519..10986)
                     /locus_tag="VQT46_001219"
     CDS             complement(10519..10986)
                     /locus_tag="VQT46_001219"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET2371252.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(10987..12192)
                     /locus_tag="VQT46_001220"
     CDS             complement(10987..12192)
                     /locus_tag="VQT46_001220"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET2371253.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQT46_001221"
     CDS             complement(12212..12847)
                     /gene="ribE"
                     /locus_tag="VQT46_001221"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET2371254.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQT46_001222"
     CDS             complement(12832..13932)
                     /gene="ribD"
                     /locus_tag="VQT46_001222"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET2371255.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(14067..14181)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            14338..14931
                     /gene="ruvA"
                     /locus_tag="VQT46_001223"
     CDS             14338..14931
                     /gene="ruvA"
                     /locus_tag="VQT46_001223"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET2371256.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDGLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            14941..15504
                     /locus_tag="VQT46_001224"
     CDS             14941..15504
                     /locus_tag="VQT46_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET2371257.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRDFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            15501..16178
                     /locus_tag="VQT46_001225"
     CDS             15501..16178
                     /locus_tag="VQT46_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2371258.1"
                     /translation="MMSNKNKGILIFAILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     VGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(16319..17350)
                     /locus_tag="VQT46_001226"
     CDS             complement(16319..17350)
                     /locus_tag="VQT46_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET2371259.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGRALFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNAGHATPRAIVPFGVHAHVDAQE
                     QVIRFDYNK"
     gene            complement(17605..18288)
                     /locus_tag="VQT46_001227"
     CDS             complement(17605..18288)
                     /locus_tag="VQT46_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET2371260.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASVFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(18300..19244)
                     /locus_tag="VQT46_001228"
     CDS             complement(18300..19244)
                     /locus_tag="VQT46_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET2371261.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            19376..22207
                     /gene="uvrA"
                     /locus_tag="VQT46_001229"
     CDS             19376..22207
                     /gene="uvrA"
                     /locus_tag="VQT46_001229"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET2371262.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAIKASSVEQIVDKVLELPERQRLQILSPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDNSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPNASKTLHEGALAPWNPISSNYYPNMLEQAMTAFGVAMDKP
                     FEDLSEEDKNLILYGSDGKKFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCHGYRLNDQALSVRVGGEQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            22200..23261
                     /locus_tag="VQT46_001230"
     CDS             22200..23261
                     /locus_tag="VQT46_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2371263.1"
                     /translation="MNKRVQAFLAKMQEKELDGVIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
BASE COUNT         7035 a         4105 c         4754 g         7418 t
ORIGIN      
        1 agatctgaaa taactgttat gatatagagg attgaaacta gaatagtaca cctctgcttc
       61 taaaacattg ttagaaatcg atttgactgt cctgatcgat ttatcctgtt cttatttcat
      121 ttcactatag taaggtgcag caggataaag aaaaaccgag aagtttcttt ctcggatttg
      181 cttattatga ggttcctatt ttctatgctc caagagttga ttgatgtgat ctactttttt
      241 agcctctctt ttatagagaa tagcccagat gatgagatag acaatcgcaa actcgataat
      301 gagctggagg tagaaaatcc agtggaaagg gaaccaacca gcaagagttg ctagtgggac
      361 aaagccagcc agcataagga agaaatgagt cagagtggca cgaagcatgc tccagtcacg
      421 gctgaataag cgattgccaa agttgaagag cataccaatg gctgcccaga taagtgtgca
      481 gtagagcaag accaaggcac cgtgaacctg atgctgatcc atcacttggc cgatgagaga
      541 gtagggattt agtggtgcgt aggtatttgg tgcataaatg agtgaaaaga ggatagagag
      601 gatgaggccg ataagaacac cggcagctgc atcgtgaaat acttgttttt tcatagttct
      661 aatttctcct tgatggtttt tagataacgg cgtgaagagt aggtgaagct ttcgtttttc
      721 aagaaaattt ctaccagacc gtttggcgtg agcttgaggt gagagatgga atcgatattg
      781 atgatttctg attgggaaat ttggataaaa ttggttggca agagtttaag aacctgatag
      841 agtcgcaaat caatgctgta ggtctgactc gcggtttctg ctagaacctt ccgattctcg
      901 atatagaagc gctgaatctt gccaatctca actagataga cctgatcatc gattttccct
      961 ttgatttttt ctctttggtc cagattttct gcgaactcga tgactttctg aactttatct
     1021 gtcggctgag gtgcttggac aatcagcttt tcctcctcgt aagtctcact aatctgtaat
     1081 tctactttca taaatttctc tccttgtttt tcatacaaaa ttaatctcac ttcttgtaca
     1141 cctttattaa tactcttcaa aaatctcttc aaaccacgtc agcgtcgtct tgccgtagga
     1201 tagttgttga ctttgtcagt tttatctaca acctcaaaac agtgttttga gctgtctgcg
     1261 cctagctttc tagtttgctc tttgattttt attgagtata ccactatttt actccctctg
     1321 gcaaggtact ttgtctatgt ggagggattg ggctcctatg tggtggagct tttctgttct
     1381 ttctgaaata tggtataata gcactaatca atttctagga aaatagatac agaaaggggc
     1441 tgaaagaact aggggaacag ttgtaattag aaggtgatag gtatgaaaag tggcgttgaa
     1501 gctggataag tttataaaga gtttgaatga agaaatgaaa agtaaataag ttgatgatga
     1561 attgcaaaaa tagattttat atacaatttg tatctttcaa atcattgatt tgaattttag
     1621 atttaatcat gttacaatta aaaatgaaat caaatagaag aggaagatgc aaacgtgggc
     1681 acactattag caacaagatt aaaaaataga cgaaaagaat taaaaatgtc tcagcgagaa
     1741 ctagctgaag gtatctgtaa acaggggcaa atcagtcgat tagagagcgg agagtttact
     1801 cctggagcag atttcttgca tgcccttgct aagaagttaa aagtcagtat ggattatttt
     1861 tttgatgagc aggttgtaga gaaagttgag gagttatcag aatttaagaa attagcacag
     1921 acatttatta caaatcgcaa ttatgagtct ttgaaatata tatatgaatt ggagaatgta
     1981 aaagctcacc gcctatcttt agcagataaa atctacatgg aatggataaa atctctgata
     2041 gatttttatt tttacggaca gaaagaagat gcgattgtac gattagaggg ggtattatca
     2101 cagttaagtg tatctgattt gaactatctc caagtttcaa acaccctatt caatttttat
     2161 tatgatattg gagatttagg tcgtttcaat aaaattcgtg aaaaactaga gtatcaagta
     2221 aatcacctca atttgagtac aatcgaagag ttagaactat ctattaagtt taactacaac
     2281 gtttgtcgtt atctatggtt acagaaaaat attgaagaag ctattactaa aattacagct
     2341 actataaaac aatgtaaggc ttacagaacg aattatcttt tggctgattt gtacttattg
     2401 atgggaaatg taagtgaaaa tttttcttct aaaagttcgg tgaaagaata ttttgagacg
     2461 gcatattttc tatacaaact tgaggagaac atgtcaatga ctctgaaagt tgagcattac
     2521 attgcagata taacagaata atgaatacgg tgttcaagtg agcatcgttt ttcaaaccta
     2581 gttcagatac aaaaaagtat caaataaaaa aaaataaaaa aacattataa aaacaattga
     2641 caagctaatt ttgaagtgat aaaataaatg caagaaaaca aaaggagagg tatatgagaa
     2701 gtttgtttaa gaaaatagtt gctgtattag ttattggctt aattctgtta ggaattgcga
     2761 gaacacctca agttcataag atggctagag ggattgatcc tggtcctgcg aattttattt
     2821 agaaatcaat ttctactaat tgagtactaa ttgagtatta atgggtaaaa agattgtatg
     2881 gataagaaaa atttacttgt attggttact ggttcggtag gtgccagtaa tgtagataca
     2941 tacttatatt atataaaaaa attctataat gttaaagtga tactttctga aaattctaaa
     3001 aaatttataa gtaaggaatt aattagttat ttttgtgata aagtttatga tgaaatattt
     3061 gttgaagagg tagttccgca cgtttttctg ccatatgaat ctgacttact tcttatttta
     3121 ccagctacgg caaatgtgat tggcaaaatt gctaatggta ttgctgatga tttagttaca
     3181 gcaactgttt taaactttaa taaaaaaata attttttgtc ccaatatgaa ctctactatg
     3241 tgggacaatc acatagttca aagaaatgta tcaattctaa aggagttggg acatatattt
     3301 ttatttgagt ctaaaaaaac atatgaggta ggattgcgta aagcaataga ttcaacatgt
     3361 tcaatgttac aaccacagtc gttagtaaaa gaacttatca aattagaaaa tattgtcctt
     3421 gaagagggac attaaaaact actgagaata ttaaggaggg gaaaaaatgg aaaattcatc
     3481 aatcgatgta gatatgctgt tggaagaatt gacacaagaa gcaatggtcg ttgttgctgt
     3541 tgataaggac tgttaattta aacttatggc aatatatgaa aggttactgg atgttttaaa
     3601 ttatgcaggc agtagccttt tattatatac aaatggataa agtaaggata atacaatgat
     3661 taataaaaaa atacaacaag ttgttttgga atcattacag aattttttga atgggaactt
     3721 catttcgcct tgtgtagtct atgattttgg cttgctggaa actgtacttg atgaatttaa
     3781 aaatcaaatt cctgtaacat tcaattacca acttttttat gccgttaaag caaattcaaa
     3841 tgagaagata cttgaattct tagtagataa aattgatgga gttgatgtgg cgtcattatc
     3901 tgaattagat gtggctaaaa aatttttccc accaactcaa atttctgtta atggtcccgc
     3961 attttcttat gaaactttat ataatctgat taaaaaacaa tataaagttg atattaactt
     4021 tttggaacat cttcaacaat tttccccaaa agaatctgtt ggaataagag taacggagcc
     4081 agatgaactt aataatcgta tgagtcgatt tggaataaat atttgcagtg ataattggac
     4141 tagtaattta caaaatcctt taattacacg actgcatttt cattttggag aaaaagatga
     4201 taaatttatt gttaagttag ataaaatatt atttaagtta caagaaatta ataaacttag
     4261 agaggttaga gaaataaatc ttggaggcgg ttttatgaaa ttatttatgg aaaatcgttt
     4321 gaaagaattt tttctatcac ttatggaaat ctataaaaag tacgatattg atagtactgt
     4381 gactacaata atagaaccag gtagtgcaat tacttcattt tctgcctata tgattactag
     4441 cccagttaat gttagtgagg tgaatgagca gcaggttatc acgttagaca catcaatata
     4501 caccaataca ttatggtttg ttccgcatat tattacaacg ttaaattcaa gtagtaaaga
     4561 gcgttatagt actattctct atggtaatac ctgttatgaa catgacaagt ataaaatgaa
     4621 agtttcgctt ccaaggttaa ctcaaaatag cagtatagtg ttttttcctg taggagctta
     4681 tataaaaagc aatcattcaa atttacatcg taatgatttt atgcgggagg tatatttgtg
     4741 gacaaaaaac ttgacatatt agataaagtt aaggaatatt taggaaataa aactactcaa
     4801 attctggata atcaatataa agaatttttg aaacttaatg atataaggcg agcgtttggt
     4861 atttcagaaa aagtattaaa caattctttt aattttacga gtaaagaatt taatgattta
     4921 attaataacg aaaattattt attcgaatat gcatgtagaa ttagagagga atggagaaaa
     4981 aaatgcttta atcattctta tcgttttcta tgctcaccta taattacaga tgattttctt
     5041 aacacgaaga cattgagaag tagccaaatt gaatataaat atgagcgata tttatcgaaa
     5101 agttcgatag gcgatagagc ggttgatggc tttgtttcct tcaatacttt aacagctaat
     5161 ggtatgtctg ctattaaact atgtcttgag atattaaact ctattttctt caagaagaag
     5221 attgatttat tatattcaac cggatattat gaaacaagat ttttattaaa taatcttgct
     5281 aaatcaggta ttagttgcta tgaggtaagt aattgtgaat tggataaaga taaattttat
     5341 aatgtattca tgatggaacc caatcgagcc gatttaacat tacaaaaaac tgatttcaag
     5401 atagtagaat attttgttaa gtataaaaat aattcaataa aagtcgttat tttagatatt
     5461 tcatatcaag gttctaattt taaattagta gaatttttag agaaatttaa atttgcgaat
     5521 gtaattattt ttgtggtacg atctttgata aaattagatc aaatgggatt agaattgaca
     5581 aatgggggaa taatagaagt gtttattcct aatcatttga gaaagttgaa aaattttatt
     5641 gaagaggaat tcaataaatt tagaaattct cacggagcta atctaagcct ctatgaatac
     5701 tgtttgcttg ataattcttt aaccttaaaa aatgattgga actattctga tttagttatg
     5761 aaatttacga gtaattttta tgctgatata aaagacttgt tcatggaaaa ttctgatatt
     5821 gaaatcatcc atgaagaggg agtacctttt gtatttttag atttaatagg tgaaggtaaa
     5881 aaagaatatg aaatgttttt tcaatggtta aacttctttt acaaacagct tggaatcaca
     5941 ttgtatgcta gaaatagttt tgggtttcgg aatctaacag tagagtattt tggaattatt
     6001 gggacagaaa gatatatatt taagatttgt ccaggtgttt ataaagggtt aagttattat
     6061 ttgatgaaat ttttattaaa atctttttca aatgaatatt taaaaactac tgatgaggtt
     6121 aatagatgaa aaatttgata aagttgctaa taattagatt gattgttaac ttagcagaca
     6181 gtgtatttta tatagtagca ttgtggcacg ttagcaataa ttattcttcg agcatgttct
     6241 taggaatatt tattgcagta aattatctac cggatttgtt actaatcttt tttggaccag
     6301 ttattgacag agtaaatccg caaaaaattc ttataatatc aattttggtt caattagcag
     6361 tggctgtaat atttttatta ttattaaacc aaatatcatt ttgggtgata atgagtctag
     6421 tgtttatttc agtaatggct agctccataa gttacgtgat agaagatgtg ttgattcctc
     6481 aagtggtaga atatgataag attgtatttg caaattctct ttttagtatt tcgtataaag
     6541 tattagattc tatttttaat tcattcgcat catttttaca ggtggcagta ggatttattt
     6601 tattggttaa gatagatata ggcatatttt tacttgctct atttatattg ttgttgttaa
     6661 aatttagaac tagcaatgcg aatatagaaa acttctcttt caaatattac aagagagaag
     6721 tgttgcaagg tacaaagttt attttaaata ataaattatt atttaaaacc agtatttctt
     6781 taacgcttat aaactttttt tattcatttc agacagtagt tgtaccgatt ttttctattc
     6841 gatattttga tggtccgatt ttttatggta tttttttaac tattgctggt ttgggtggta
     6901 tattgggaaa tatgctagcg ccaatcgtaa taaaatattt aaaatcgaat caaattgttg
     6961 gtgtatttct ttttttgaac ggctcaagtt ggttagtagc aattgttata aaagactata
     7021 ctttatcact tattttattt ttcgtttgtt ttatgtctaa aggagtcttc aatattattt
     7081 ttaattcgtt gtaccaacaa atacctccac atcaacttct tggtagggta aatactacca
     7141 ttgattctat tatttctttt ggaatgccaa ttggtagttt agttgcagga acgcttattg
     7201 atttgaatat tgaattagtg ttaattgcta ttagcatacc ttattttttg ttttcttata
     7261 ttttttatac ggataatgga ttgaaagaat ttagtatata ttagaaatgt ttatgttcat
     7321 tcaaaagcat aatgactata actgaaaaag aaaagtgata tctttaaggt tgttcttctt
     7381 ggtggtgaga ttcgtgagac aacccaagct tttgtcggaa agattaccaa tgctttgatg
     7441 gataggatgt actttagcaa gatgttttta gtggtaacgg tatcgtggat ggacgtgtaa
     7501 taacctcttc tttcgaggag tattttacta aaaaactagc cttggagcgt tccccagaaa
     7561 cggacttact cattgactct tcaaagattt ggggagaaga ttttgcttca tctgttcctt
     7621 gaaaaaagtc acagcagtca tcacagacga tagtactgaa caaaactatg aagagttaga
     7681 aatttatacg caggtgattg tataaaggat ctggaaatag ataagaagtt gattagtatt
     7741 gacctaggtg gtacaaatat taagattact gttctttcaa atgacggtga gattgaaact
     7801 ttgtggagta ttacaacaga tacaagtgag aaaggttctc aaattatatc ggacatcatc
     7861 agttctatta aaaataaatt gaccgaacgg aatattcctg atagcgacct tcttggaatc
     7921 ggtatgggaa gttgctcatc atactttcct tgtaaatcat aggggctata aactctccgt
     7981 ctacttgtcc tgcaacaatt gaagtctgct caaaacgccg tccgctaatc ttttcataga
     8041 ctttctccct tttaggagcc tagctttcta gtttgttctt tgatttttat tgagtatacc
     8101 actattttac tccctctggc aagggacttt gtctatgtgg agggattggg ctcctatgtg
     8161 gtggagcttt tctgttcttt ctgaaatatg gtataatagc actaatcaat ttctaggaaa
     8221 atagatacgg aaaggggctg aaagatgtct catattattg aattgccaga gatgctggca
     8281 aaccaaatcg cagctggaga ggtcattgaa cgtcctgcca gcgtggtcaa agaattggta
     8341 gaaaatgcca ttgacgcggg ctctagtcag attatcattg agattgagga agctggtctc
     8401 aagaaaatcc aaatcacaga taacggttat ggaattgccc acgatgaggt ggagttggcc
     8461 ctgcgtcgcc atgcgaccag taagataaaa aatcaagcag atctctttcg gattcggacg
     8521 cttggttttc gtggtgaagc cttgccttct attgcgtctg ttagtgtctt gactctgtta
     8581 acggcggtgg atggtgctag tcatggaacc aagttagtcg cgcgtggggg tgaagttgag
     8641 gaagtcatcc cagcgactag tcctgtggga accaaggttt gtgtggagga tctctttttc
     8701 aacacgcctg cccgtctcaa gtatatgaag agccagcaag cggagttgtc tcatatcatt
     8761 gatattgtca accgtctggg cttggcccat cctgagattt cttttagctt gattagtgat
     8821 ggcaaggaaa tgacgcggac agcagggact ggtcaattgc gccaagcaat cgcagggatt
     8881 tacggtttgg tcagtgccaa gaagatgatt gaaattgaga actctgacct agatttcgaa
     8941 atttcaggtt ttgtgtcctt gcctgagttg actcgggcta accgcaatta tatcagcctc
     9001 ttcatcaatg gtcgttatat caagaacttc ctgctcaatc gtgctatttt ggatggtttc
     9061 ggaagcaagc ttatggttgg acgttttcca ctggctgtca ttcacatcca tatcgaccct
     9121 tatctagcgg atgtcaatgt gcatccaact aagcaagagg tgcggatttc caaggaaaaa
     9181 gaactgatga ccctggtttc agaagctatt gcaaatagtc tcaaggaaca aaccttgatt
     9241 ccagatgcct tggaaaatct tgccaaatcg actgtgcgca atcgtgagaa ggtggagcaa
     9301 actattctcc cactcaaaga aaatacgctc tactatgaga aaactgagcc gtcaagacct
     9361 agtcaaactg aagtagctga ttatcaggta gaattgactg atgaagggca ggatttgacc
     9421 ctgtttgcca aggaaacctt ggaccgattg accaagccag caaaactgca ttttgcagag
     9481 agaaagcctg ctaactacga ccagctagac catccagagt tagatcttgc tagcatcgat
     9541 aaggcttatg acaaactgga gcgagaagaa gcatccagct tcccagagtt ggagtttttc
     9601 ggacaaatgc acgggactta tctctttgcc caagggcgag atggacttta catcatagat
     9661 cagcacgctg ctcaggaacg ggtcaagtac gaggagtacc gtgaaagcat tggcaatgtt
     9721 gaccagagcc agcagcaact cctagtgccc tatatctttg aatttcctgc ggatgatgcc
     9781 ctgcgtctca aggaaagaat gcctctctta gaggaagtgg gcgtctttct agcagagtac
     9841 ggagaaaatc aatttattct acgtgaacat cctatttgga tggcagaaga agagattgaa
     9901 tcaggcatct atgagatgtg cgacatgctc cttttgacca aggaagtttc tatcaagaaa
     9961 taccgagcag agctggctat catgatgtct tgcaagcgat ctatcaaggc caatcatcgt
    10021 attgatgatc attcagctag acaactcctc tatcagcttt ctcaatgtga caatccctat
    10081 aactgtcctc acggacgtcc tgttttggtg cattttacca agtcggatat ggaaaagatg
    10141 ttccgacgta ttcaggaaaa tcacaccagt ctccgtgagt tggggaaata ttaaaagtat
    10201 aaaaaagtct gggaaaaatt ttcaaaatca gaaaaacgca taaaatcagg tgttcaaaaa
    10261 ccttgatttt atgcgtttta tcatggaaat agttacttca tgttttccta attcttttcg
    10321 aaactctttt taaaccacgt cagttttatc agtaatctca aaacagtgtt ttgagctaat
    10381 tttgccagtt ttatctgtaa catcgaagtt gtgtttgacc actctgcgac tggtttccta
    10441 gtttgctcta tgattttcac agagtattaa attgcgattt tgccaagttt ctttattcgt
    10501 ctaaaagtag agtctgttct atgcgtctaa tgtacgaatt aggttgacca tttcaatagc
    10561 tccttgtgca cactcagaac ccttatttcc tgctttggta ccagctcgtt ctatggcttg
    10621 ttcaattgta tctgtcgtta gcacaccaaa cataacagga atttcgctat ttaaactgat
    10681 ttgggcgatt cccttagata cctcgctaca tacataatca taatgacttg tattccctct
    10741 aatgacagct cccaagcaga taattgcatc atatttttta ctttttgcca tttttgatgc
    10801 aatcagtggt atttcaaaag ctcctggaac ccaggctacc tctatatctt tctcgtttac
    10861 attctctctt ttgagattat ctagtgctcc agataataat tttgaagtta taaattcatt
    10921 aaatctcgct acaacaatac ctattttaat attgtttgct actaaattac cttcataagt
    10981 gttcatttat ttttcctcca tatttaaaat gtgacccatt cgatttttct ttgtttctaa
    11041 ataaaaacta tcgtaaggat tggcttctat ttcgattgat attctactgg aaatggtaat
    11101 tccatatttt tctaactgtt caaccttgtc aggattattt gtcagtaaat gaagtgactg
    11161 aagtcccaga tctttaagca tttgtgctcc aatatgatat tctcttaaat caccttcaaa
    11221 gcctaatgca agattggcat caagcgtatc catgccttga tcttgtaaat gataggcttt
    11281 taatttattg ataagtccaa ttcctcgtcc ctcctgtcgc aagtaaagta agacacccga
    11341 accattctca acaatcattt tcatagcttt atcgaattgc tgtccacaat cgcaacgtaa
    11401 agagcctaaa acatctcctg ttaaacattc ggagtggacc cgacataata cattggcttc
    11461 atcctctata tttcccataa taagagcaag atgatgttcc ccatttagtt tatctatata
    11521 gctaattgct ttgaaattac cgtatctagt aggcatattg acagttgaaa ctcgttctac
    11581 cagctgatca tatacttttc tatattcttg taattctttg atggtaatta gtggaatgtt
    11641 gtgtttcttc gagaactgaa ttaaatcatc tgttctcatc attttgccat catgattcat
    11701 tatttcacaa cataggccac actcttttag tccagctaat tttaataaat caacagttgc
    11761 ttctgtgtgt ccatttcttt ctagaacacc accttttttt gcaattaaag gaaacatgtg
    11821 tcctggcctg cgaaaatcag agggtgttat atcttcagct acacacatac gtgcggtcag
    11881 tcctctctcc tcggcagaaa tacctgtggt cgtttcttta taatcaattg aaactgtaaa
    11941 agcagtctta tgattatctg tattgttttc aaccataggt gaaagcatta attgattagc
    12001 taaactttcg ctcataggca tacaaattaa tcctttggca taagtagcca taaaattaac
    12061 attttctgtt gtagctgctt gtgcagaaca aattaagtct ccttcatttt ctctatcctt
    12121 gtcgtctata acaagaacaa gtcgtccctt ctgcaatgct tctaatgctt cttgtatttt
    12181 tcgatattcc attgactgat tatcctttct gctaaaatcc attttgatat aatagttcct
    12241 tagatatttc tgattttgga gagttatcca tcagtttttg cacatattta cctaagatat
    12301 cattttcaag atttactgta ctcccgactt gtttactctt aagaatggtt tgttccaagg
    12361 tatgagggat aacagatact gaaaagttta ctttggagac tttagcgaca gtcagactaa
    12421 tgccgtcaat tgtaatagat cctttttcaa ctattaaatc taaaatttct ttttgtgtgt
    12481 tgatttgata ccatacagca ttatcatctt tttttattga cgagattttt cctgtaccat
    12541 caatgtgtcc tgtaacgacg tgacccccaa gtcgaccgtt gacagataag gctctttcta
    12601 gattcacctc acttccatgt tttaatagag taagagctgt tcgactccat gtttcattca
    12661 ttacatcaac tgtaaaggat tgatgattga aatgagtaac tgtaagacag ataccattta
    12721 ctgctatact atcgcctaaa tggatatccg ttaatatttt tgaggcttta attgatagtt
    12781 tacaattacg agagtctttc tgtattcttt caacttttcc gatttcttca attattcctg
    12841 tgaacatgga taaatcactt cactttctat gagatagtca tttcctattt gagaaaaagc
    12901 ataaggtttc aatctaatag cgtcatttgg caaagaaatg ccttcacctc cgacaggaaa
    12961 cttggcactg cctccaaaaa tttttggtgc aatatatatt ttcagctcat caacaatttg
    13021 ttgttccaaa gcactccaat tcattagact gcccccttct agaactaggc tatcaatctg
    13081 catgtttcct agatgttgca ttaaactcga taagtctata tgattgcctt ttttctttat
    13141 ggaaagtatt tcacagccat gattttgata tagcttcatt ttatttttgt cttcagagga
    13201 agtggcaatg taagttttaa tatcatttgc tgtttttacg attttagagg taagaggagt
    13261 tcgtaaatgt gtatcgcata tgatacggat aggatttttc ccttcctcca atctacatgt
    13321 cagcaaagga tcgtcttgaa taacagtatt gactcccacc ataattgcac taacatggtg
    13381 tcgtaactga tgcacatgct ttcttgcttc ttcttcagta atccatttgg attgatttgt
    13441 tttagtggct atttttccat ccattgacat tgcatatttc ataaaaacat agggtacatg
    13501 ctgggtaata tactttctaa aactttttat taagttaaga cactcatttt ctaaaattcc
    13561 aacagtaact tgaagattat tttcctcaag tatctttact ccttttccag atacaatagg
    13621 attacagtct aggcttccaa tgactactct tgtaatacca ctatcgatta tagcatctat
    13681 acagggaggt gttttcccga agtgacaaca gggttcaagt gttacataaa gcgtcgctcc
    13741 gacaggggat tctctacagt ttttaagagc atttctctca gcatgtgggc caccaaaaaa
    13801 ctcatgataa ccttgtccga tgatgtgatt atcttttaca ataactgcgc cgaccatagg
    13861 attgggattg acgtaaccag cccctttttg tgccagtttt attgctaatt tcatatattt
    13921 tgaatcgctc atctcactac ctccaaaaaa aatatacctt gaatagggga ctactcaagg
    13981 catacaaaag aaaacttatg cgattaacaa aaatactctg aaatgacaag taatcatttc
    14041 agagcacgca aaaagcacaa atatactttt atcttctttc atccagacta tactgtcggc
    14101 tttggaattt caccaaatca tgcctttcgg ctcgtgggct ataccaccgg tagggaatta
    14161 caccctgccc tgaagatagt tattcaatta cagatgatta tagtacttaa ttttgaatat
    14221 gtcaacagat aaataccgat tgtttttgat atactgtatt tgtgataatc gattctcgct
    14281 cctcggataa agaaaatatg atatactaga taaacgaaat aagagagaag gaatactatg
    14341 tacgcatatt taaaaggaat cattaccaaa attactgcca aatacattgt tcttgaaacc
    14401 aatggtattg gttatatcct gcatgtggcc aatccttatg cctattcagg tcaggttaat
    14461 caggaggctc agatttatgt gcatcaggtt gtgcgtgagg acgcccattt gctttatgga
    14521 tttcgctcag aggatgagaa aaagctcttt cttagtctga tttcggtctc tgggattggt
    14581 cctgtatcag ctcttgctat tatcgctgct gatgacaatg ctggcttggt tcaagccatt
    14641 gaaaccaaga acatcaccta cttgaccaag ttccctaaaa ttggcaagaa aacagcccag
    14701 cagatggtgc tggacttgga aggcaaggta gtagttgcag gagatggcct tcctgccaag
    14761 gtcgcagtgc aagcaagtgc tgaaaaccaa gaattggaag aagctatgga agccatgttg
    14821 gctctgggct acaaggcaac agagctcaag aaaatcaaga aattctttga aggaacgaca
    14881 gatacagctg agaactatat caagtcggcc cttaaaatgt tggtcaaata ggagcagaga
    14941 atgacaaaac gttgttcgtg ggtcaagatg accaacccac tctacatcgc ctatcatgat
    15001 gaggagtggg gccagcccct ccatgatgac caagcgttgt ttgagttatt gtgtatggaa
    15061 acctatcagg caggcctgtc ttgggaaacg gtactcaaca aacgccaagc tttccgagaa
    15121 gcctttcata gctatcaaat tcactcagtc gcagagatga ctgacactga attggaagcc
    15181 atgctggaga atccagctat cattcgaaat agagccaaga tttttgctac acgcgctaac
    15241 gcccaagctt ttctacagtt acaggcagag tacggctctt ttgatgccta tctttggtct
    15301 tttgttgagg ggaaaactgt cgttaacgat gttcctgatt atcgccaagc cccagctaaa
    15361 acacccttat ctgagaaatt agccaaagat ctcaaaaaac gagacttcaa gttcacaggc
    15421 ccagtcgccg tattgtcttt tctacaggct gcagggctag ttgatgacca cgagaatgat
    15481 tgtgagtgga aaggtcttaa atgatgtcta acaaaaataa gggaattctg atttttgcga
    15541 ttctctatac agtcctcttt gtgtttgatg gcgttaaatt gctggcttct ttaatgccat
    15601 ctgccattgc aaattatctt gtttatgtag ttttagctct atatggctcc ttcttattca
    15661 aggatagatt gatccaacaa tggaaggaga ttagaaagac taaaagaaaa ttcttctttg
    15721 gcgtcttaac aggatggctc tttctcattc tgatgactgt tgtctttgaa tttgtatcag
    15781 agatgttgaa gcagtttgtg gggctagtcg gacaaggtct aaatcagtct aatattcaaa
    15841 gcacttttca agagcaacca ctactgatag ctgtttttgc ttgtgtcatt ggacctctgg
    15901 tagaagaatt atttttccgt caggtcttat tgcattactt gcaggaacgg ttgccaggtt
    15961 tactaagcat tattctggta ggacttgttt ttgctctgac tcatatgcac agtttggctc
    16021 tatcagagtg gattggtgca gttggttact taggtggagg ccttgccttt tctattattt
    16081 atgtgaaaga aaaagagaat atctactatc cactacttgt tcacatgtta agcaacagcc
    16141 tctccttaat cattttagct atcagtatag taaaatgaaa taagaacagg acagtcaaat
    16201 cgatttctaa caatgtttta gaagtagatg tgtactattc tagtttcaat ttgctgtaat
    16261 atgtgatgaa aatgccagta atgataccga gaaaaaagct gagaaacttt tcccagcttt
    16321 atttgttata gtcaaagcga atgacttgtt cctgtgcatc tacatgagca tggaccccaa
    16381 agggtacaat tgctcttgga gttgcgtggc cggcattcag attatagaca atcgggatat
    16441 tgctgtcaat gatatccaat agtgcctctt tatagtcgtc atggaaagtt tcatccatag
    16501 gttttccgac caagagtcca ttgatgaccg cgaatatgcc agtgtccttt aaagttagca
    16561 acatcttttt gaagtcttct ggcttaggct tttcttcgct tgtttcgagc aagaggattt
    16621 tcccttccca gtctgacaag tcagggaaaa gtttgtattt ttggcagagc tccgtgctat
    16681 ctgcgtatcg agagttgtca aagatatcgt agagggattc gaggcaacca ccgaggattt
    16741 tcccctcgaa tagtgccctt ccttgcaaca agtcaaaacc tgtatttgta tgactgacac
    16801 gaggtgttcc cagggccgtg ggactaaaat cagttcgttc ctcataccaa acgtcactag
    16861 ggcggatttc tgaaattctt cccgtctcaa tcaattcttt aaagtagtga aggctatagg
    16921 ctagcatttc tttgtctaat tcacaaatgt ctgctaaaaa ggattgacca taaaaagtct
    16981 tgattcctaa tttatgcaac atgaggtggt tcatggttgt atccgagaag ccaagaaaaa
    17041 ttttttgctt gataaccttt tggagttggt cattttcaaa aagataaggt agcaagcgat
    17101 aggtatcgtc tccaccgatg gcacatagga tcatgtcgat gctatcatca gaaaaggcat
    17161 gaatcaaatc ctctgcacga gcttcaggat ggtccttgat aaagtctaat ccttttaacg
    17221 aatggggcaa aaagatggga ttgagtccca gatccttgag acgttggata cccaagtcca
    17281 cttcgtgttt gacaaaatcc tctccgataa tgccactaga taaactaaca ataccaatag
    17341 tagaaaccat atctcatcct cctagaaata gattgagcct attttatcac aaaatataag
    17401 agaaagctat gtgggatttc agaagaatac ttttaatact cttcgaaaat ctcttcaaac
    17461 cacgtcagtt ttatctgcaa cctcaaagct gtgctttgag caacctgcag ctagcttcct
    17521 agtttgctct ttgattttca ttgagtataa ctcaaaaaag taagtgaaaa agcaaccgca
    17581 cctgcagttg cttttatcgt tttcttattc ttgatagcgt gttggtcctg cacttgcact
    17641 acggatattc aagcgtttct tgagatagaa gcgaagggct aggagggctg ctccaataat
    17701 agctagtggc aatggatcca gtactgggtt aaggctagct ggtaggaagc ttgttgcaaa
    17761 gaagacaagc aaccaaagga acacagaagc taggataact agtacagatt tccagaaagg
    17821 tggacgttga ctgcgatcca tatctggtcc atagtattgg taaacaaagt agtacatcaa
    17881 gtagaaggca aatccaccaa ccagtccaac taatagaaga gtaatcaatc catagccgaa
    17941 agcttgatct gccgcaaaga aggttgtgag ggcgctgaca agggcaaaga ggctagtgat
    18001 gaaaagagct gagtccataa tcatcagttt tgggtcatca ttttcttttg gatgctcttt
    18061 ttcgtactgc tctttgacag tgaagctatg agcccaatga gttggtgcgc cgtataggga
    18121 acgggcagtt gtacctttag attgctcctc aaggatttgg ggaatgactt cctcaaaaat
    18181 agtctggatt tcagcgtctg ttttcccatc tttgatgaat tgttgggtag caatgtggac
    18241 aaactcttgg tttttcttag ttaatttttg tagatcaatt tgagacatag gaactccttt
    18301 tagaaccatt ttttatggat gagatagaga gtgagcgaga cactcatagc aaaggcgata
    18361 aagacgatta accagaaggc atttggctct ccgtttaggg gaatttcatt atccttaaag
    18421 ttcatcccgt aggcagaaaa gaccatggtt gggatggaca tgacgatggt cacaagggcc
    18481 aaggttttca tgatgttgtt ctggttgtta gaaatgatag aggcaaaggt ctctgtcata
    18541 gaatgcaaga cgtttccata aatatctgcc atctcgatgg cctgttgggt ttcaatcagg
    18601 gtgtcttcaa gcaggtcttc gtcctcaagg tatttcttga tattgctggt tgaactggtc
    18661 aatttcttaa tcacgcgctc atttgttttg agggaggcct tgaaatagac gatagttttt
    18721 tccaattcca tgagctcaat caattcttca ttacgagttg attgatgcag ttgactttcg
    18781 atttgttcac tcttgcggtc gattgaacga agggctgtta ggtaaagctc tgcattgcga
    18841 taaagaattt gaaagataaa acgtgaacgc atgaaggtat agaaattacg caatcgacgg
    18901 ttgataaaga catcaaggac aggtagtggt tccaaacacg tagtgataat ggtttcctca
    18961 gtgatgataa taccaagcgg gatggttacg tagtaggtgc ggttatttct ttcctccgtg
    19021 accggcacgt ctacgataat cagggtatac tcgtcttcaa tggtaatacg agacatttct
    19081 tccgcatcga gcggtgctcg aaggtcggca atatcaatat cgaaggtgtt ggcgatttcg
    19141 agtgattcat tttgagtcgg attgacgaga ttgatccaag tacccggttc aagcgtatcg
    19201 atctctttaa attcagttgt tgtagagaga aaaacttgtt tcatatccct tatcctttct
    19261 catttttcag attttttcac actgtactat tatactacaa aatcggcctt ttgggtaata
    19321 gaatctcact ttttttggta taatggtaag caataatgga ctagaaagaa caaagatgca
    19381 agataaaatt gtcattcatg gggcgcgtgc ccataattta aaaaatattg atgtggagat
    19441 tccgcgagac aagttggttg tcgtgactgg cttgtcaggt tcagggaagt ccagtttggc
    19501 ttttgatacc ctctatgcgg agggacaacg tcgctatgta gagagtttgt ccgcctacgc
    19561 tcgtcagttc ttgggaaata tggaaaaacc agatgtagat gccattgatg gtctcagccc
    19621 agctatttct atcgaccaga aaacgactag caaaaaccct cgctcgacgg tgggaacaac
    19681 gactgaaatc aatgactatc tgcgtctcct ctacgcgcgt gtggggacgc cttactgtat
    19741 caacgggcat ggggctatca aggcttcttc tgtggagcaa atcgttgata aggttttgga
    19801 gttacctgaa cgccagcgct tgcagatctt gtctcctgtc atccgcaaga aaaaaggcca
    19861 acataagagt gttatcgaga aggttcagaa agacgggtat gttcgtgtcc gtgtggatgg
    19921 ggaagtctat gatgtgaccg aagtgccaga gttgtctaag agcaagcaac acaatatcga
    19981 tgtcgtggtt gaccgtattg ttatcaagga gggcattcgt agtcgtctct ttgattccat
    20041 tgaggctgcc cttcgtattg cagaaggtta tgtcattatc gacaccatgg acaactctga
    20101 gttgttgttc tctgagcatt atgcctgtcc agtttgtggt tttactgtcc cagagttaga
    20161 gcctcgtctc ttttctttca atgctccttt tggctcttgt agtgagtgtg acggcttggg
    20221 catcaagctg gaggtggata ctgatttggt agtgccaaat gccagcaaaa ccttacatga
    20281 gggagcgctg gcaccttgga atcctatctc atccaactac tatccaaaca tgctagagca
    20341 ggccatgacg gcttttggag tggctatgga taagcctttt gaggacttgt cagaagaaga
    20401 caagaacttg attctctacg gctcagatgg taagaaattc catttccact atgagaatga
    20461 atttggtggc gtgcgcgata tcgacattcc gtttgaggga gttatcaata atatcaaacg
    20521 tcgttaccat gaaaccaata gcgattacac tcgcactcag atgcgcctct acatgaatga
    20581 gctgacttgc ggaacctgtc acggttatcg tctcaatgac caggccttgt ctgtccgtgt
    20641 gggtggtgag caagggccac atatcggaga aatttcagac ctgtctatcg cagatcactt
    20701 ggacttggtg agccagttaa ctttgtctga aaatgaagcc atcattgctc gtcccattct
    20761 caaggaaatc aaggatcgtt tgaccttcct taataatgtg ggtcttaact atctaaccct
    20821 gtcacgttca gcaggaaccc tttcaggtgg ggaaagtcag cgcattcgtt tggcaaccca
    20881 gattggttcc aacctatcag gcgtcctcta tatcctagac gagccgtcaa tcggtcttca
    20941 ccagagagac aatgaccgcc tgattgccag tctgaaaaag atgcgtgact tgggcaatac
    21001 tcttatcgtg gtggaacacg acgaagatac catgcgtgaa gctgattatc tgattgacgt
    21061 tggtcctggt gccggtgttt ttggtggtga gattgttgca gcaggtacac ctaagcaagt
    21121 ggctcgcaac agcaagtcta tcacaggtca gtacttgtca ggcaaacgtg tcatcccagt
    21181 accagaagag cgccgtgtcg gaaatggtcg ttttattgaa gtgataggag cgcgtgagaa
    21241 caacttgcaa aatgtcacgg ctcgctttcc actaggaaaa tttatcgcag tgacaggtgt
    21301 gtcgggttca gggaaatcga ctctaatcaa cagcattctc aaaaaagcca ttgcccagaa
    21361 gctcaaccgt aattcagaca aacctggtaa gtttaagact attacaggga ttgagcatgt
    21421 cgaccgtttg attgatattg accagagccc tatcggacgg acgccgaggt ctaacccagc
    21481 tacctataca ggagtttttg acgatatacg tgaccttttt gctcagacaa atgaagccaa
    21541 gattcgaggc tacaagaagg gacgcttcag tttcaacgtc aagggaggtc gctgtgaagc
    21601 ttgctcaggt gacgggatta tcaagattga gatgcacttc ttgccagatg tttatgtggc
    21661 ttgtgaagtt tgccacggaa cccgctataa cagtgaaacc ctagaagttc actacaagga
    21721 aaagaatatt tcgcaggtct tggatatgac ggtcaacgat gcggtagaat ttttccaaca
    21781 cattccgaaa attcaacgca aactccagac catcaaggat gtagggctag gctatgtgac
    21841 cttgggacag ccagctacca ccctttctgg gggagaagcc caacgtatga agttagctag
    21901 cgaactccac aaacgctcga caggaaaatc tttctacatt ctggatgaac cgacgacagg
    21961 gcttcataca gaggacattg ctcgcctgct caaggtttta gctcgctttg tagacgatgg
    22021 caatacagtc ctcgtcatcg agcacaatct ggatgttatc aagacggcag accatatcat
    22081 tgacttggga cctgagggcg gtgtcggtgg tggaaccatc atcgtaacag gaactccaga
    22141 agaagtagct gccaacgaag ccagctatac aggacactat ttgaaaggaa agttacatca
    22201 tgaataaacg cgtacaagca tttctagcta aaatgcaaga aaaagaacta gatggtgtca
    22261 tcatcaacaa tcttaaaaac gtctattatt tgactggttt ttggggctca aacggaacag
    22321 tctttatcag ccgtgaccgt caggtattag tgacagactc tcgctatatc atcgcagcta
    22381 agcaagaaac cagtggtttt gagattgtgg ctgatcgtga tgaattggct gtcattgcag
    22441 gaattgttaa ggacatgggc ttgactcgta tcggttttga agatgagatt tcagtgtctt
    22501 attaccaccg tatgcaggca gcttttgcag gtttgaactt gcttccacaa actcagtttg
    22561 tggaaggtct tcgtatgatt aaggatgagg cagagattgc agcgattcgc aaggcttgtt
    22621 ctatctcaga ccaagctttc cgcgatgcgc ttgactttat caaaccagga aaaactgaaa
    22681 ttgagattgc caacttcctt gatttccgca tgcgtgagtt gggagcatct ggcttatctt
    22741 ttgatacgat cctagctagc ggtatcaatt cttctaaacc ccatgcccat ccaatgcaca
    22801 aaccagtgga gttgggagaa gccattacca tggacttcgg ctgtctctat gaccactatg
    22861 tcagtgatat gacccggact atctatctag ggcatgttag cgatgagcag gcagagattt
    22921 acaatacggt tctaaaagct aaccaagcct tgattgacca agctaaggca ggcttaggtt
    22981 tccgtgactt tgacaaaatc cctcgtgata ttatcattga ggcaggttat ggtgactact
    23041 ttactcacgg cattggccac ggtattggtc tggatatcca tgaggaaccc tactttagtc
    23101 agacttctac agaaactatt aagacaggta tggccttgac cgatgaacca ggtatctata
    23161 tcgaaggcaa atatggcgtt cgtatcgagg atgatatcct gattacagag acaggttgtg
    23221 aattattgac cctagctcca aaagagttga tagtcattta gttgtttgtc aagaaaaaag
    23281 tacgaaaatg acgaaaaaag tcaaaaaaaa tt
//
LOCUS       DAVAZV010000032        23023 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVAZV010000032 DAVAZV010000000
VERSION     DAVAZV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23023)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23023)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23023
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.032"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..337)
                     /locus_tag="VQT46_001231"
     CDS             complement(<1..337)
                     /locus_tag="VQT46_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002202361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371264.1"
                     /translation="MDSASIIAHTIHQKFNLKVPNYRQEEDWARMGLPITRKEIANWH
                     IKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSQLTYYWTFLSGKSEKQGIT
                     LYHHDQCRSG"
     gene            complement(345..650)
                     /locus_tag="VQT46_001232"
     CDS             complement(345..650)
                     /locus_tag="VQT46_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase zinc-finger binding
                     domain-containing protein"
                     /protein_id="HET2371265.1"
                     /translation="MFPVETEEITYKRKKSKGKRQALLAQFDSEEVHHQVEESICSDC
                     QGDLKEIGATLQRQELVFIPAQLKRIDHIQHAYKCQACSDKNPSDKIVKAPIPKAPL"
     gene            complement(637..831)
                     /locus_tag="VQT46_001233"
     CDS             complement(637..831)
                     /locus_tag="VQT46_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371266.1"
                     /translation="MKIIQQQSATIDSLTNALALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLNLFEEESPSEKDGDVPS"
     gene            complement(907..1247)
                     /gene="tnpB"
                     /locus_tag="VQT46_001234"
                     /pseudo
     CDS             complement(907..1247)
                     /gene="tnpB"
                     /locus_tag="VQT46_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1228..1413)
                     /locus_tag="VQT46_001235"
     CDS             complement(1228..1413)
                     /locus_tag="VQT46_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371267.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(1717..3279)
                     /gene="guaA"
                     /locus_tag="VQT46_001236"
     CDS             complement(1717..3279)
                     /gene="guaA"
                     /locus_tag="VQT46_001236"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET2371268.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3421..4119
                     /locus_tag="VQT46_001237"
     CDS             3421..4119
                     /locus_tag="VQT46_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET2371269.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4162..5058)
                     /locus_tag="VQT46_001238"
     CDS             complement(4162..5058)
                     /locus_tag="VQT46_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET2371270.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLLIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5067..6002)
                     /locus_tag="VQT46_001239"
     CDS             complement(5067..6002)
                     /locus_tag="VQT46_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET2371271.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(5999..6724)
                     /locus_tag="VQT46_001240"
     CDS             complement(5999..6724)
                     /locus_tag="VQT46_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET2371272.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(6808..7443)
                     /locus_tag="VQT46_001241"
     CDS             complement(6808..7443)
                     /locus_tag="VQT46_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET2371273.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKSLKDYLY"
     gene            complement(7445..8272)
                     /locus_tag="VQT46_001242"
     CDS             complement(7445..8272)
                     /locus_tag="VQT46_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2371274.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8294..8630)
                     /locus_tag="VQT46_001243"
                     /pseudo
     CDS             complement(8294..8630)
                     /locus_tag="VQT46_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
     gene            complement(8631..9347)
                     /locus_tag="VQT46_001244"
     CDS             complement(8631..9347)
                     /locus_tag="VQT46_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HET2371275.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPVEVMDAIKEAGYHVLDLAHNHILDSQIEGVISMADII
                     EKAGITPIGVYTHEPRDQAPLVIKEVNAIKVALLAYSYGFNGIEQYIFQEDYNRYLSD
                     LNEDKIKAEVERAEKEADITIIMPQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSKTVEKDGDKKLIIY"
     gene            9870..10481
                     /locus_tag="VQT46_001245"
     CDS             9870..10481
                     /locus_tag="VQT46_001245"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET2371276.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEGIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10526..11254
                     /gene="rlmB"
                     /locus_tag="VQT46_001246"
     CDS             10526..11254
                     /gene="rlmB"
                     /locus_tag="VQT46_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET2371277.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEMTEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(11293..12204)
                     /gene="trxB"
                     /locus_tag="VQT46_001247"
     CDS             complement(11293..12204)
                     /gene="trxB"
                     /locus_tag="VQT46_001247"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET2371278.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12270..12494)
                     /locus_tag="VQT46_001248"
     CDS             complement(12270..12494)
                     /locus_tag="VQT46_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET2371279.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12572..13315)
                     /locus_tag="VQT46_001249"
     CDS             complement(12572..13315)
                     /locus_tag="VQT46_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2371280.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILLLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13315..14115)
                     /locus_tag="VQT46_001250"
     CDS             complement(13315..14115)
                     /locus_tag="VQT46_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2371281.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14273..14629)
                     /locus_tag="VQT46_001251"
     CDS             complement(14273..14629)
                     /locus_tag="VQT46_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2371282.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14642..15154)
                     /locus_tag="VQT46_001252"
     CDS             complement(14642..15154)
                     /locus_tag="VQT46_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET2371283.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(15154..15648)
                     /locus_tag="VQT46_001253"
     CDS             complement(15154..15648)
                     /locus_tag="VQT46_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371284.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15783..16229
                     /locus_tag="VQT46_001254"
     CDS             15783..16229
                     /locus_tag="VQT46_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET2371285.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16226..16873
                     /locus_tag="VQT46_001255"
     CDS             16226..16873
                     /locus_tag="VQT46_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET2371286.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(16894..17475)
                     /gene="pdxT"
                     /locus_tag="VQT46_001256"
     CDS             complement(16894..17475)
                     /gene="pdxT"
                     /locus_tag="VQT46_001256"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET2371287.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17476..18351)
                     /gene="pdxS"
                     /locus_tag="VQT46_001257"
     CDS             complement(17476..18351)
                     /gene="pdxS"
                     /locus_tag="VQT46_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET2371288.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18503..19882)
                     /locus_tag="VQT46_001258"
     CDS             complement(18503..19882)
                     /locus_tag="VQT46_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2371289.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKDKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            20177..21100
                     /locus_tag="VQT46_001259"
     CDS             20177..21100
                     /locus_tag="VQT46_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET2371290.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGISPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21160..21765
                     /locus_tag="VQT46_001260"
     CDS             21160..21765
                     /locus_tag="VQT46_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2371291.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKTIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLTHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            21783..>23023
                     /locus_tag="VQT46_001261"
     CDS             21783..>23023
                     /locus_tag="VQT46_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET2371292.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRNFKFKFELEVLEIDEVPMF
                     NQDEKWDESFQLRFLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGAS"
BASE COUNT         6846 a         5158 c         4197 g         6822 t
ORIGIN      
        1 aaccacttcg acactgatca tggtggtaaa gcgtaatccc ttgtttctct gatttacctg
       61 acaaaaaagt ccaatagtaa gtcagctgac tatcactttc taagacccga taagaggttt
      121 catctgcatg aagaagaggt tgttctaaca acttttctcg taaaaggtta taaagggact
      181 ctaaatagta ttgactcgcc ttgatatgcc aattagcaat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattagg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaagctg agtcaatagt ctcgttataa aggggcttta
      361 ggaataggag ctttcacaat tttatcactc ggatttttat cactgcatgc ttggcatttg
      421 taagcgtgtt ggatatgatc tatgcgtttt aattgcgcag gaataaagac taattcttgt
      481 cgttgaaggg ttgctccaat ctcttttaga tctccctgac aatcagagca aatgctctct
      541 tctacttgat gatgaacttc ttctgaatca aattgggcaa gaagagcttg gcgtttccct
      601 ttagatttct tacgtttgta ggtaatttcc tctgtttcaa ctgggaacat ctccatcttt
      661 ctcagatgga gactcttcct caaaaaggtt gagttgtcca gaggggcaaa cacttttctc
      721 agaggatttt ccatagagct tttgagtcag ataagccact tgttcacgaa gaagggcaag
      781 tgcattggtg agactatcaa ttgtagcact ctgttgttga atgattttca atcttcttcc
      841 atgggcttcc cctccttgtt ttctaccttt attatactaa aaagaaagtc ctcatttcaa
      901 tagaaatcac gactttctga tggatttatt tttggagtga tagaaaagtc cttcataagc
      961 cagtctactt gttcagatgt gagagctttg acatcctttt ctgtactggg ccaagtcagt
     1021 ctgccgttcc caaagcgttt atatagtagc caaaatcctt gaccatccca gtaaagggct
     1081 ttaaagcggt atttacgtcc accacaaaag agaaaaactt gacctgagaa aggatctaat
     1141 tcaaagtggg ttttaaccag ataagccagt gaatcaatgc cttgcctcat atccgttttc
     1201 ccacatacga gatagacctg ccctaggcta gatagatgaa ttgtcataga gcaacacctt
     1261 atccaaaagc tgttctacca tttcgagatt gagagattga aaaaaactta cttcaagctt
     1321 gccaatacga attttaagca gaatatcatt tctcttttta gaatcaaaag gacgagattg
     1381 tggaatctct acaggaacaa taggttgtgg cattaaaata tcctccaata gttttacttt
     1441 actaatagta tacaggagga actccatgaa tgatagatac cttgttatga cgcgattact
     1501 atattagaaa gttggctctc taattaaatt aattctcatt atatatatca aaagaccgca
     1561 gcttgaaaac tacggtctaa ttttttgtcc aaatgtaaac cacttggaac tattattcaa
     1621 tttattcttt ttagtaaatg ttcccgtttt aatcccagtt acagttttta atcctctgta
     1681 accgttgatt ttacaaagct tttaattttt ttgcgattat tcccactcaa ctgttgcagg
     1741 tggtttactt gtaatatcgt agacgatacg gttaacatga tccacttcat ttacgatacg
     1801 tactgagatt ttttgaagta cttcccatgg aattttggca aaatcagcag tcataccatc
     1861 gatagaagtg atagcacgga ttgcaatcgt gtagtcatat gtacgaccgt cacccataac
     1921 accgactgaa cgaacgcctg tgttaacagt gaagtattgc caaatatcgc ggtcaagtcc
     1981 agctttagcg atttcttcac gaagaatagc gtctgattca cgaacggttt caagtttctc
     2041 ttcagtgatt tcacccatga cacggatagc aagtcctggt cctgggaatg gttggcgcca
     2101 tacgatatgg tctggcatac caagctctgt accaagagca cgaacttcat ccttgtaaag
     2161 agtattgagt ggttcaatca attcaaactg catatcttct ggaagaccac ccacgttgtg
     2221 gtgtgacttg atagtttgag ctgtatccgt accagactcg ataacatctg tatataaagt
     2281 accttgagca aggaatttca catctttgag cttgcttgct tcgtcatcga atacatagac
     2341 aaactcgtta ccgatgattt tacgtttttg ttcaggatca gaaacgccag caagtttgtc
     2401 aaggaaacgt ttagcagcgt ctgctttgac gatattcaaa ccaaacttac caccgagcat
     2461 gtccataact tgatcagctt cgcctttacg aagaagaccg tggtctacga agatacagat
     2521 caattgatcg ccaatcgctt tttggagaag aaccccaacg acagatgagt caacaccacc
     2581 tgatagacca agaaggacac gtttatcacc gacggtttca cgaatttttt tgatctgcat
     2641 gtcaatgaaa ttatccattg accagtcacc tttagcctta caaatgttaa gggcaaagtt
     2701 acgaaggata tcatttccgt atacagaatg acgaacttct gggtggaatt ggataccgta
     2761 aatgtgttta tctgggtttt cgatggctgc gtatgggcag tcagctgatg tacctgtacg
     2821 aacaaagtca gcaggaatct cagtaaccgc atcaccatgg ctcatcaaaa cagtctgttc
     2881 atcaggtgtt gattcaaaaa gcgctgatgg tgtgtgagtt agggttgatt gaccgtattc
     2941 acgatttcca gcatcacctg caggaacaac ttttcctcca agtttatggg tcaataactg
     3001 cataccataa cagattccca aaattggaat tccgagttcg aagatttctg ggtcaatatc
     3061 aaatgaacca tcttcatata cagaatttgg accacctgat agaataattc ctacaggatt
     3121 gacttcacga acttcagcag ctgaaatttt atggcttttt agttctgaaa aaacaccaat
     3181 ctcacggata cggcgtgaaa tcagctggtt gtactggcta ccatagtcca atacgatgat
     3241 tttttctaca tcttgcaaat cagttgaaat gttgctcatc tttttccttt ctcaaaagaa
     3301 atatcttttc tcaatattct atcacaaata agggcgaatt accaactaaa caaggcgaag
     3361 tttgactttt tctagtttat tggggtacaa tagagaaaag atagaaatga agtgaaaaat
     3421 atgctacctg cttatatgaa aatccatgat cagataaaaa aggatattga cgagcaccgt
     3481 tgggctattg gtgagaggct tcccagtgaa agagatttag ctgagcagtt tgcggtcagt
     3541 cgcatgaccc tccgccaagc cgtatctcta ttagtcgaag aaggcgtctt agagcgccgt
     3601 gtaggaagcg gcacctttgt ttccagtact cgagtacaag aaaagatgcg agggacaacc
     3661 agttttactg aaattgtcaa atcccaaggt aaagttccct ctagccagct catttcctac
     3721 aaaaaaacca ttcccaatga gcaagaagtt gccaagctag gaatttttcc aacggacaat
     3781 attatccgaa tggagcgggt ccgctatgcc gaccaagttc ccctagttta tgaagttgct
     3841 tctattcctg aaaaattcat taaggacttt aaaaaagaag aaatcacaag tcatttcttc
     3901 caaaccttgc aaaaacatgg ctatcgtatc ggcaaatctc aacagaccat ctatgctcgc
     3961 cttgctaaag aaaagattgc ccactatttg gaagttgaaa aaggacatgc tattcttgga
     4021 ttgacccagg tttcctacct agaagatggt actgcttttg aatacgtaaa aagtcaatat
     4081 gtaggcgaac gctttgaatt ttatcttgaa aataattaga ttaccacgca aaaactctct
     4141 gtcacggaca aagagtcttt tttatttttc taagaataaa tctttcaaag aaatcaaagt
     4201 tacagcaaac aatatcattg ccataccaag aaaatcaatg ggataaaatt gttcattcat
     4261 tattaagaag gcaaagaaaa tcgccgatat tggctcaatt gaagccaaca agcttgactt
     4321 gaccggtcct atcagactgg ctcctttaag gaaagctgta taggcaaaga cagtcccgat
     4381 aaggataatg cctgcaaacg caaggagaaa atcaagacta gtcgggatat cggcctgtag
     4441 aacccctgta aaaggaaggg cgaccaaacc tgctatgacc attcccacac caatgagcaa
     4501 gctgctcccc cactttttaa tcaaggctat gggtaaaatg atatacagag cataagtcaa
     4561 ggcagaaaag agaccccaga acagaccagc aggtgtcatg gataactggt ccaactgccc
     4621 atgtgttgcg atcaggaagg ttcctccgat ggcgaatatg atggaaacta tctctcccag
     4681 tgtcggtgcc accctatcct tgatacagct ataaattaaa attccgacag gacaaacata
     4741 ctgaagcacc gtcgctgttc ccgcattggt ctcctgaata gcagacagat aggcgaattg
     4801 gttgagaaaa agaccaatca gagcaaaaat aagaagagac agcaaactct ttctatcctt
     4861 taaaaagacc agtattttat cctttgcagt agcataagcc aagagcatga gaattccacc
     4921 agcgattaaa agacgcaagt tggtcaagac cagagccgaa attccgtgtg ccattaggta
     4981 ttggccactc gttcctgaca acccccaagc aataccagcc acaactgtta gtaaagtccc
     5041 ttttaaacta tttgacatgt ctctccttac tcttctttgc gaatcaagtt catcacttga
     5101 ttgcggtcta atatccattg agctctctcg tccttttcat aggtacgatt cgataggaaa
     5161 atagtggctt cttgcttctg acgattccac atgataaagg tacctgtata gcccgtatgg
     5221 tctagccaat ctccttccaa attccatgct aaagaacgtt ccttgtcatc caaaggagaa
     5281 aaattttgat ttaagtctct tgcaaaatca tctgctaaat agtgttctaa aaagatttgt
     5341 aaatccttta tagtcgaaaa taaaccagca ctcccagcat gtctacccag gagacgagcc
     5401 ttgggatcat gcactatgcc tgcctctaca cctctaactg ttggaacagc aagctcaact
     5461 ggcccaaact tggtttccgt cattccccaa ggtttccaga cttgatcctt taaaatcaca
     5521 tccaaatctt gattaaaaat tctttccaaa ataaagccca acagcaaaaa atggacatcc
     5581 gaataaagaa aggctggctg acttcgtctg ttgagatgaa acatcgcttc ctttaattca
     5641 ggggctgtta aaagatcacg attaggaata aaaggatcaa ggtctgttgc atgagtcaag
     5701 agctggcgaa tagtgatgtc tggataatca ctctcaggta aaaaatctat taccagtcta
     5761 tcaatatcta attgacctat ttcccacaag aaggtacaaa ctgtgccaac cccaacaacc
     5821 ttgctgacac tagctagatc ataaactagt cctgcctcag tctgcaagcc atgctctggg
     5881 tcactctggc ctaaatagaa ctctgtccat tgattgtcct taaaatacgc aaaagaggct
     5941 ccgggataaa ttcctgcctc gatttgttct tctatttttt taataatctt ggtccacttc
     6001 atacttcttc aaaccacaat tcaacattat ttctatcttt accaaggaag aatttttcag
     6061 acttaggaat aaaatattca gtagactcaa acttctggcg aagacttgct atgtctaatt
     6121 cattgaccaa gaacttgagc atagataagt cccaggtaac cgtattgtcc acagtcaaat
     6181 cctgcccctg agctggaata aaatcaaggg atgccccaat ttcagatgat tccaagaaac
     6241 tttcgatatc agttgggaga tgtaattcca tagaaatctc aaatttactt aaagaaattg
     6301 atgccaaatc tgtttgaaat tcaggctttt ctcctacttc tactagactt gctctgtcat
     6361 cttccgcatg aatcaaaatc aaatcatctt ctggtgagaa aatttcaaaa gcgtagccat
     6421 tttgaccttt atataatcga tgaatcgaat ctgttttaga taagattcct tcaatttcta
     6481 agggattttc caccttgaca atcaatctag ctagtttttt tcttccctct accttacgag
     6541 tacgcatact gggagcttct tctaaaacca gcttttcaag acccgtttgg tcacctagtg
     6601 acagaaaggc cgattcttct aacaaggcct tcattccaag ggtttcaata taaaatgttt
     6661 catttaattt tctattatta gcttttaaag taggaataat ccgtacaatc tgatttacat
     6721 tcataaattc ctccgtcact ttttatttta aaggatttta gaatttttta caagatatta
     6781 tgctcaaatt taacattatt tagctattta gtaaagatag tctttcaagg attttgacaa
     6841 agcctgataa ccagcaatac tgaggtgcag tccatcagtt gtatattctt ttttgagttg
     6901 gcctgcttgg tctgtcaaac aatcaaatac tggcacaaat tccacctgca tataggcaga
     6961 tgcaagctct tgataggctt gattccagtt ctgaattttt tcattcgagc ggatatagac
     7021 tgcctgctgg tactcctctc cctcattgac aggcaaaatg gaaagcaatt taatctctgt
     7081 caatggataa tcgcgagcaa cggattgaat gatagcttcg agattattga gagcctcatt
     7141 cacaggaaca tcctttccga tatcatttgt cccaatcaga agaaaaattt tatctactgc
     7201 tccaccatat agatgagcat caagattctc tagtaacagt cctgtctgat agccacgaat
     7261 tcctcgattg acaatcgtct ttgaagtccc aaatagctcc tgtagaggat aatactcgac
     7321 aatggaatcc ccaataaaaa gaatgtttgg ttctacaaca gaaatgtgat ttaggtgacg
     7381 atacttagtt tgaatttttt cttgttcctt taggagccaa ttttctaata actgtactgc
     7441 cacttcattc tcctttttct aaccagtttt ccaagacttg ataaactcct ccttggctgt
     7501 tggctggtgc tagagcagtc gccacagctt tggctttctc atcagcattt tccatcgcat
     7561 aggcaattcc agccatttca agcatttcaa catcattttc actatcacca aaagccatga
     7621 tttcttggga tttcaagtcc cagcgcttga gtaattcctc caagccccat gctttatgaa
     7681 tcccagcttg gaggatatca atgcaaccat agccactgga tacagctcgg acacggccat
     7741 caaagagagc attgatttct tccaaaaccg aactcaaacg ttcctcacca acaaccatgc
     7801 tcatcttgag cacaccacca aagaggtcag atgttaattc atccacaaat tgcatccgtt
     7861 ggtagaattt ttcaatcatt tctggagtca taaaactttc aagatctgta aaaatcgtac
     7921 cttccttgac aaaatcaccc ttcatccccg ttacaacaaa ctggtcctga cacgctcgac
     7981 ccttgaaatg agccaaagcc ttgttgacaa tggcgtcatc ccatgtctga gcctgaatca
     8041 attcattgtt ttcaaaaata cgagcgccat tagcaacaac cagaaccact cgatccacca
     8101 agggactcag tagttgtctc atgcggtgaa tttcattgcc cgtcgcaatg acaaaacgaa
     8161 tgcccctttg atccaactga tctaaaatct tttccaatcg tgggagatca agctgacccc
     8221 tagcatccag caaggtccca tccatatctg tcgcaattac cttaatcatc atttactttc
     8281 ctctggattc aagctaatac cacttcaatc ccacatgttc attcatttct ttataggctg
     8341 tatcaattcg ttccttagtc gcttcatcta actggtcacg atgactgcca cccctctata
     8401 aaatcttcca aaatataagt ttggtaatga tacaagggat atccttctgg tgaaaaggtt
     8461 ccctttggtg ttcgattgac ccaagtagga tgagctttag ctgttccgat agttgttttt
     8521 ccatccttct tcttgatggt gacatccatg agaacaccac gttcagtcca cttagcattc
     8581 tcttcatctc ccatagattc aatccgttga ttggaaatga agttccccat ttaatagata
     8641 atgagtttct tatctccatc tttttcaacc gttttagatg gttcaacaac gtgaggatgc
     8701 cctccaaaga taatatccgc tccccaatcg atcatcttgt gataaagagc tttttgttct
     8761 tcagttggtt ccaatcgata ctcaacaccc atctgaggca tgataatggt gatatctgct
     8821 tccttctctg cccgttcgac ttcagccttt atcttatctt cgtttaaatc tgaaagataa
     8881 cgattatagt cttcctgaaa aatatactgc tcaattccat tgaaaccata ggaataggct
     8941 aacaatgcaa ccttgatagc attcacttcc ttaatgacca gcggagcctg atcacgtggt
     9001 tcgtgcgtat aaactccgat tggagtgatt ccagctttct caataatatc ggccattgaa
     9061 ataactccct caatttgcga atccaaaata tgattatgag ctaaatccag cacatgataa
     9121 cctgcttcct taatagcatc cataacttca acaggagcat taaagagaag ataacccgct
     9181 aaataatgat ccttattaat ggttccttca aaatcaccaa tagctaaatc tgcttgcttg
     9241 agccaaggag tcacatactc aaaattttca tgaaagtcat aggtaccgtc ttctttttta
     9301 gctgaaaaga aaagtccatc gtggtagagc aaatccccgt gggccataat tctggcagtt
     9361 ttttcctctt cctactcctg agacttttgc ttagtcccct cttgagaaat agtatctcgt
     9421 ttttgactag tcaagggatt ccttggaagc tttcaaacaa caagaccaag cccattgata
     9481 aaccaactgc tagcaagagt atcgccacaa atcccttatt gctccacttg cgataactcc
     9541 taaaaagttt accaagccct tcataaaacg aaaagctaaa ccaccctgat ttcgattttg
     9601 tcttctttgt atcttcattc tccctacttt cttatgcaag ccttttcttt ttattatatc
     9661 acagataagt atttctttca caattgaatt gaacttccca tctattttct ataaatccta
     9721 aatgccataa tgctttcaat tcttgtcatt ttgtgatatc atgtagaggt aatgaaagga
     9781 aatgaactaa tccacagtgg cttattccaa gtataccact tgggctttgg cagtagttaa
     9841 ctgcactaaa cataatataa ggagagaaaa tgtctgcaat agaacgtatt acaaaagctg
     9901 ctcacttaat tgatatgaac gatattatcc gtgaagggaa tcctactcta cgcgcgattg
     9961 ctgaggaagt cactttcccc ctatctgacc aggaaatcat cctaggcgaa aagatgatgc
    10021 aattccttaa acattcccaa gatcctgtca tggctgaaaa aatgggactc cgcggtggtg
    10081 ttggactggc tgctccccag ttagatatct caaaacgcat tatcgctgtt ttggtaccta
    10141 atattgttga agaaggcgaa actccacagg aagcctacga tttggaaggc attatgtaca
    10201 atccaaaaat cgtctctcac tctgttcaag atgctgctct tggcgaagga gaaggttgcc
    10261 tgtctgttga ccgtaacgtg cctggctatg ttgttcgcca tgcccgcgtt actgttgact
    10321 actttgacaa agatggagaa aaacaccgta tcaaactcaa aggctacaac tccattgttg
    10381 ttcagcatga aattgaccac attaacggta tcatgtttta cgatcgcatc aatgaaaaag
    10441 acccatttgc agttaaagat ggtttactga ttcttgaata aagaaaatcc cgttgcaaga
    10501 cggggttttg tgttataata gaggcatgaa aacaaatgat attgtctatg gtgtccacgc
    10561 cgttaccgaa gccctccttg caaatacagg aaacaaactc tacctccaag aagatctccg
    10621 aggtaagaat gttgagaaag tcaaggaact agctacagaa aagaaggtgt ccatttcttg
    10681 gacatcaaaa aaatctctct ctgagatgac tgaaggtgct gttcatcaag gttttgttct
    10741 acgagtgtct gaatttgcct atagcgagct agattacatc cttgcaaaaa cacgccaaga
    10801 agaaaatcca cttctattga ttctagatgg tctaaccgat ccccataatc tgggttctat
    10861 cttgcgaaca gccgatgcga ccaatgtttc aggtgtcatc attcccaagc accgtgctgt
    10921 cggagtaact cctgtcgttg ccaaaacagc cacaggtgct attgaacacg ttccaattgc
    10981 ccgagtgaca aacctcagtc aaaccttaga taaactcaag gatgaaggct tctggacctt
    11041 tggaacggat atgaacggta ctccttgcca caagtggaat acaaaaggga aaatcgccct
    11101 catcatcgga aatgaaggaa aaggcatctc tagcaacatc aaaaaacagg tcgatgaaat
    11161 gattaccatt ccgatgaatg gacatgttca aagcctcaat gccagtgttg ctgcagccat
    11221 tctcatgtac gaagtttttc taaatagact ataaaaaagt ttccagtcat ctgattggaa
    11281 acttttttat gattaactat gttctgtgat aaacttgtag gcttcttgac cagcgatagc
    11341 tccatctcca actgctgttg ttacttggcg aaggtctttc aagcgaacat ctccaactgc
    11401 aaagataccg tcgactgcag tcttcatgtg gctatctgtc acaatccagc ctgcctgatc
    11461 ttggatattc aattctttaa caaaatcgct aagagggtcc aaaccaacat agataaagac
    11521 accaccgaag gcttgctctg tcacttgacc tgttttcaca ttttcaaaaa cgacagattc
    11581 tactctgttt tcacccttga tttccttcac tacagaatcc cagataaagc tgattttttc
    11641 attcgcaaag gcgcgatctt gtaaaacctt ttgggcacga agttggtcac gacggtgaac
    11701 aatggtaaca gtcttagcaa aacgagtcaa gaagagggct tcttcaacag ctgaatctcc
    11761 accaccaact accaataaat cttggtcacg gaagaaagca ccatcacaca cagcacagta
    11821 agaaacacca cgactgttca gttcttcttc tccaggcact cccaaaggac ggtgtttaga
    11881 accagttgct acgataactg tacgtgtttc atatgtttgg tcatcagtca tcactttctt
    11941 aaaatcacca tggtcttcga cattttcaac ataaccataa atgtgctcaa caccaagatt
    12001 ttcaagtggt tcaaacatct tttcagccaa ttcaggtcca ctaatattag cgtatcctgg
    12061 gtaattttcg atatcagatg tattattcat ctgaccacct ggcagaccac cttcaatcaa
    12121 agctactttt agattgcttc gagcagcata caaggccgca gtcatccctg caggtccagc
    12181 accgataata atagtatcgt acatatagat tccttctttc ttgttgtaac tatctttatt
    12241 ctaactcttt cttgtcaatc acgcaaggat tatgccttga aaacaagaat taaactcata
    12301 accgcaaagg ataatactgg gacaaccaag actccaatca taatcatatc atagagatgg
    12361 gcttggcgag ccctggctgt cttatcaact cccgacatgg ctctcagacc aatccaaatc
    12421 cctaaaaaaa tcagaacaag gatggtggtc aagatcaaac tctcgaaata taaagaaaat
    12481 agttgcagta gcatgatttc tctcatttct atctttttta aagagtaaac tcagctagtc
    12541 caactaactg agttttcctt tatctattat atcaaatata agtccgtttg taactagcga
    12601 agaattcttt tgtccgctct tctttagggg tgtggataat ctcatccgga gttccagact
    12661 cgatgatttt ccccttatct aataagagaa ttttatccgc aacttgggct acaaaggaca
    12721 tgtcatgact gaccaaaatc atggtctgac ctgacttagc agcatctgca atagactttt
    12781 ctacttcacc gaccaattct gggtcaaggg ctgaagttgg ttcgtctaag agcaaaacat
    12841 ctggtttcat agcaagcgca cgcgctaggg caacccgttg cttctgtcca cctgataaat
    12901 ggcgaggata atggttttca cggtccgaaa gcccaacctt agccaactct tccttggcaa
    12961 tcttagtcgc ttcttggtca gataatttct tgacaacaac caagccttct ttcacattat
    13021 caagtgctgt tcgacgttca aataaattaa actgttggaa aaccatagac aacttacggc
    13081 gtagggcaag gatttcttct tgagtgattt tagaaaaatc aactgaaaaa ccatcaatct
    13141 gaatagagcc actgtcaggt gtttcaagat aattgagact gcgaagaaag gttgattttc
    13201 cagctcctga agaaccaatc aaggctacaa cttccccttt ttgaatatcc aagttcagat
    13261 gatccaagac agtctgtcct gaaaaggatt tgcttaaatt cgaaatctta atcattaacg
    13321 aaggtctcct ttcacatctg tttgcactgt atcaggtgca gaaatagcca tttttctctc
    13381 gatgaaacga ccgaggcttt caattccgat attgactacc caataaacaa gggcaacaga
    13441 gatgaagcgt tcaaaatagc gataatcagc tccacctaga atctgagctt gggcaaagac
    13501 ttccacaaca cccgcactaa aagctagaga tgttcccttg gtcaaaccga tgagggaatt
    13561 aatcaaggtt ggagtagcta ccaccgctgc attaggaata atcactcgtc gataaacttg
    13621 cgctcgggtc atacccagac tgcgcgccgc ctcaatctca ccaggattaa ctgagagaat
    13681 ggctgcacga atggtttcac tagcataagc tgcctcatta aaggcaaaag cgacaatcgc
    13741 aaaagctgca gctggaatcg cattgatatt gagaccagtt ccccattgct gattgagggc
    13801 tttcaaagcc aaagggattc cgtagtaggt caacatgagt tgcaccaaaa tcggtgtccc
    13861 ttttaagaaa ctaacaaaga aggcctgcaa gggatataaa atcttgacac gattgatctt
    13921 cacaatggca aaaagaagcg ccaaaaccaa gccaaaaagg gcaccaccaa ttgtcaacat
    13981 aattgttgtt ggaagttgtt ggacaattct agggattcca tcaaagaccg aacgtaggct
    14041 aaacagcttg ccatccggaa tcaattgcat caagttttgg taccaatctg atgctaaaat
    14101 cgttgtaaca ttcataaaaa catcctcttc tgataatgat tcattctacc atgcttctgc
    14161 cgtcaatgaa attatttgct acggtcagat acagactttg tctacctact agtttatcat
    14221 actttgaaac agggaagtta tatattttat ctatcaaaga gatagataaa aactatttca
    14281 gtcccagttc ttcataagat tttcgataac cgatttgctt aacagttcca ttttctacta
    14341 aaatgggccg ttttaacaac ataccgtcac ttgctagcaa ctcagccgct tcttggtttg
    14401 acaaacttcc taccttatct tttagcccta attcacggta tttgatacca ctggtgttga
    14461 aaaattgctt caattcaaat cctgaggttt ctagccaatt caaaatgact tcttggctag
    14521 gtgtttcttc cacgatatgg acggctttat agtccacacc taattgattt aattcttgtt
    14581 ttgctttttt acaagttgaa catttggggt attcgataaa ttctaacatg tgcttctcct
    14641 tctatttgtt tatatcttta aaatctacgc cttcatgctc caagagccaa gctttctttt
    14701 ccactcctgc agcatagcct gtcagacgct tgcctgctcc caacacacga tgacaaggta
    14761 ctaggataga ccaaggattg cgtcccactg ctccaccaat tgcttgagca gaagccactt
    14821 gcaggtcttg agcaatttgt ccataggtca ctgtctgacc ataaggaatg ccctgtaaat
    14881 agtcccaaac tctcttttca aaattcgttc cgattggcgc caagagcaag ttggataaat
    14941 cctgaggctt gcctttaaag taatcatcta agcaagcaat aactgggtct aaaataggat
    15001 gactaacaac ttcttctatc gtttcatctc ctagtcccct ctcaaaatgc ttctgctcct
    15061 gaacccaaat tccatacaaa taatggtcat cagctacaag tgatagaata ccaattggtg
    15121 aggagtagag tatttttaca tacttctttt gcattatttc tttaattttt gataggccaa
    15181 gcgttcgcca tctactggca ccttaccaac ttgtttaaaa ccaagttttt caaaaatatg
    15241 ttgcataacc ttgttttcag catgcgtatc tgagcgaaaa tcaagataat caaaaccttc
    15301 aatcaagccc tctaagaagg tttgagcaac tccttttccc tgcacatctg ctgccacagc
    15361 aatacggtga aagactagat actctgactc tccagcttgc cagtttccct cataaatagc
    15421 ttcataggcc tcctctggac tcttggtcac agcagcatag gctagcagtt ctccctcttc
    15481 caaggctacg taggcttgcc ctgagatgat atcatcgata ataacatctg catttggata
    15541 gccattttgc cactggtcac taccagcatc tgctaaacat tttttggcat cctccatcac
    15601 ctgcatgatg gcatctactt catttggaaa agctaaacga atttccatct tttttcctca
    15661 tttctgacta gtttctccca tcatagcata atttaagtat ttctacaagc agttaaaact
    15721 tgactttgtg tttttgttat tttataatct agttatcaaa actatataaa aaggagttga
    15781 aaatgaaaac taccttttcc tacccaaaat gggcagaaat tccaaacatt gacctctatc
    15841 tggaccaggt tttgctctat gtcaatcagg tctgcgcccc tatctctcct aataaagaca
    15901 agggcctaac agcatctatg gtcaacaatt atgtgaaaaa tggttacctg acaaagcctg
    15961 acaaaaaaaa ataccaacgc caacagattg cccgtttgat tgctatcaca accctcaagt
    16021 ctgtattttc tattcaagaa atagcccaga cacttaatac tctacaaact caagcaagtt
    16081 cagaccaact ctacgatgct tttgtggact acatgaacca aggaattgac ccagctaacc
    16141 ctattatcca aaccagctgc caaaccgtca aactctatca tcaaactcta gacttaatcg
    16201 atcatactca agaggaggta atccaatgaa cactagtctt aaactcagca aacaactcag
    16261 ttttggagag gagattgcta atagcgtgac ccatgctgtg ggtgcagtca tcatgcttat
    16321 cttgctgcct atttcatcca tctatagtta tgaagcacac ggatttttat cctctatcgg
    16381 cgtttccatt ttcgtcatca gtctctttct catgttccta tcatccacca tttatcactc
    16441 tatggcctat ggttcgaccc acaaatatgt tttgcgaatc attgaccatt ctatgattta
    16501 cgttgccatt gccggctcat acacgcccgt tgtcttgacc ttgatgaata actggtttgg
    16561 ctatctgatt attgtcatcc aatggggaac gaccatcttt ggtattctct ataaaatctt
    16621 tgctaaaaag gtcaatgaga aatttagcct tgctctttac ctgattatgg gctggttggt
    16681 tctggctatc attcctgcca ttatcagtca aacgacaccc gttttctgga gtctcatggt
    16741 aactggcgga ctctgttata cagttggagc tggattttat gccaagaaaa aaccttattt
    16801 ccacatgatt tggcatctct ttatcctagc tgcgtccgca cttcaataca tcgctattgt
    16861 ttattacatg taaaaaagtt gagaaattca atctcaactt ttttctttac acatattgat
    16921 aaagtactgg tgcaagcgca catcatcagt caattctgga tgaaaagaac ttaccaacat
    16981 atttttttct tgggctgcaa caatttgatt gttcactgtt gctagaattt ctacaccctc
    17041 accaacacta ctgataatcg gaccacggat aaaggtcatt ggaatcttgc caactccctt
    17101 acattctgct tccgtgtaga aacttcctaa ttggcgccca taagcattac gctcgaccac
    17161 catatccata gttcctagat gactctcttt ctgagaagtg atttccttag ccagcaaaat
    17221 taagcccgca caggtcccaa acactggtaa gccagataga atggcttctc ggatgggaag
    17281 tagcatgttc tggtcacgta agagcttgcc catggttgta gactcaccac caggcaaaat
    17341 caaacccgac aagtcactct gatcttgctg aaaatcatct agatttctga gttctacact
    17401 ctcgacacct aattgatcta gcacttttgc atgttctgca aaggcccctt gcaaggccaa
    17461 tattccaatt ttcatctatt ttcctcgttc agccatgaga atttggattt cattttcatt
    17521 aataccaacc atggcttctc ctaaatcttc agagatttga gctaggattt gaggattacg
    17581 gaagttagtc acagccttaa caatggcact cgctcgttta acaggatctc ctgacttgaa
    17641 aatacctgaa ccgacaaaga ccccctctgc ccctaattgc atcattaacg cagcatctgc
    17701 tggcgttgca acacctccag cagcgaaatt tacaactggc aattttccat gttcatgaac
    17761 atattggacc aattctacag ggacttgcaa atccttggca gcaacataaa gctcgtcctc
    17821 acgtaagttt tgaatgcggc gaatttcctg attcatcata cgcatatgac gaacagcttg
    17881 gacgatatcc cctgtccctg gttctccttt ggtacgaatc atggaagcac cttcagcgat
    17941 acgacgcaag gcttcaccca aatccttagc accacagaca aaaggaactt ggaattcttt
    18001 cttgtccaca tggaaacggt catcagctgg agatagaact tcactctcgt cgatataatc
    18061 aatttcaata gcctctaaaa tctgagcttc aacaaaatgc ccgattctga ccttagccat
    18121 tactggaata ctaaccgctt cttggatttc cttaatcatc tttgggtcgc tcatgcggga
    18181 aactcctcca gctgcacgaa tatcagccgg aattcgttcc aaggccatca cagctgccgc
    18241 accagcagct tctgcgatac gagcctgttc aggattctgc acatccataa taacaccacc
    18301 cttgagcatc tgtgccaagt ttttatttag ttcataacga ttttcagtca tttgttttat
    18361 cctcatcatt tgtattggta gctacctttt cattttaagt cagaacagaa tgaagcacaa
    18421 gataaaaaaa ctataattgt atggggacag attggctaaa aactatctga ccttaactta
    18481 aggccagata gctcattcat ttttattttt cagccgtaag ggcagccatt gtgatgtagt
    18541 tgtatggttt attgaagtgt ggcaagaaga agaggtctgt caatgccaat ttatcaattg
    18601 tcacatgctc ttggatagca agtgagaaca tgtggattcc catgctaatt gcaatatcat
    18661 gtgaaaccat ttgggcacca agaatttcac ggctatcttt gtcaaagaca atcttaattg
    18721 ctacttcatg gttgtcatgt ttcatgaatt ctggtttttg aagatcgtta aagcctgttt
    18781 cagttgcgtt gtaaccagca gctttcgctt tttcaagagt caaaccagtt gaaaccatgt
    18841 gaagaccgta gattgagata ccatttgaac cttgaacacc gattccttcc aattcatgtc
    18901 cacaagcgtt gtaggcacca acgataccag tgcgaacagc atttgaagca agagcgatat
    18961 agcttgtatc tttacgagca ttgtcataaa cagtcgcaca gtcaccaaca gcgtaaacgc
    19021 ctgggataga tgtttcttgt ttcttgtcta caaggaaggc accgttgcgg aagagttcga
    19081 tcttaccatc agcaagggct gtgtttggac ggaaaccaac tgcaaggata accatatcca
    19141 cgtcaaagct ttctttgtca gtaatcaagc gttcaacttt accatcacct tcgattgctt
    19201 taacagtttg acctagagcc aagcggatgt tgtgatcttc caagttcttc gccatcattt
    19261 gtgtgaagtc tttgtcatag taaccgttca agacagtatc aacgatatca acaaggacaa
    19321 cttcttttcc aagacgttca aaggcttcag caagttcaac accgatgtaa ccaccaccaa
    19381 caacggcgat acggtcgaga tgttggctct tgtcagaaag tttattgata acttcttcag
    19441 cattttggta caatttcacg aattgtacgt tttcaagagt tgctttaaat tcgcggtttc
    19501 ctttaacaat ttcaacacct tcgattggtg gcaagattgg tgtagaacct gtagcgaaaa
    19561 tcaatttctc gtatgattct ttgtgttctt ttccttcaac ttctgctgta accactttgt
    19621 tatcatagtc gattgaaaga actggtgaat tcatataaac cttagcacct ttagcttcta
    19681 atttgtcttt atcagaatag aacaagcctt cagcaccgtc aatttgttca ccaatccaaa
    19741 gagccattcc acatcctagg aaagagatgt tagagttttg gtcaaataca acaatttcgt
    19801 tctcatttcc aaaattatcc aacatggtat tgatacatgc tgtaccagcg tggttagcac
    19861 cgactacaac gattttactc ataaaaaatt tcctgccttc attctaaatt tactttacta
    19921 gtataccatt taccgttagc gtttacaagg gggggactat tatttcagca ttttttatca
    19981 aaaataattc cccatttatc ctgttttcaa gcctcatgaa ttttatgagc atatttcttg
    20041 actttttcca aattttgttt gtgaaaattc taactttatg gtattataat aacatgaaaa
    20101 taaaatgtaa gggcttcaat ttagatgatt atttgatatt gcaacttatt ttctataaga
    20161 gaaaggagtt ggtagcttga ctcttcgttc acattctgaa cggctaatgg ggactactat
    20221 cactatttca ttagtggatg agcaagccga tatctttctc caaaaatcct ttgacttgct
    20281 caaagagctt gaataccgct tcaacgccaa tagtcaagaa tctgagttga tggaaatcaa
    20341 ttatcaagca ggaatatccc ccgtcacagt tcatccagac ctgtttgagc tgatttcact
    20401 tgggttagag catagcctag cgctctctag ccacctcaat atcagcattg gtcccttaat
    20461 tcaaacctgg cgtatcggtt tttcagatgc caaggtcgcc cagcctcaag aaattgaatc
    20521 ggtgctgcct ctaatcaatc ctcatggtat cgagttagat tcttctactt ctactgtgtt
    20581 tttaaaacag aaaggaatga agatcgatct aggttgttta gccaaaggat acagtgcgga
    20641 taaggttgcc caatttctta ggaaagaggg ggtgacttct gccttgatca atctgggagg
    20701 gaatatcctg accattggaa aaaatcaggc aagaggggat aacccatggc aaatcgggat
    20761 tcaagaccca gccaatccta ggggaaatca tttaatgacc atccctgttg tcaataaatc
    20821 tgtcgtgact tcaggcattt atgaacgtca cctgaccgtc gatggacaag attaccatca
    20881 catttttgac agtcaaacag gatatcctgt tgaaacggaa ctagcgagtc taacaatcat
    20941 ctctgataaa tcagtcgatg gcgaaatctg gacgactcga ctctttggag aaagacctgc
    21001 ttctatcctc tggcaagtcg aaagtttgga gggcatcgaa gtcatcctca tcgataaaga
    21061 aggccaccta agctgttctt caggaattcc tactctatag agacaactgt ttcaatggaa
    21121 ttttaaaatt gtattatgta aaaagagaaa ggaaatatca tgttaaaact tattgctatt
    21181 gttggaacaa attcaaaacg ttctacaaac cgtcaattgc ttcaatacat gcaaaaacac
    21241 tttgctgaca aagctgaaat tgaacttgtt gaaatcaaga ccattcctgt cttcaacaaa
    21301 ccagctgaca agcaagtacc tgctgaaata ttggaaattg ctgctaaaat cgaagaggca
    21361 gatggcgtta ttatcggtac tcctgagtat gatcactcta ttccagctgt tttgatgagc
    21421 gctcttgctt ggttgtctta tggtatttac ccacttttga acaaaccaat catgattaca
    21481 ggtgcttctt acggtacgct tggttcatct cgtgcccaat tgcaacttcg tcaaatcttg
    21541 aatgctcctg aaatcaaggc aaatgttctt ccagatgaat tcttgctcac acactctctt
    21601 caagcattta acccaagtgg cgacttggtt gaccttgatg ttatcaagaa attggatgcc
    21661 atctttgatg acttccgtat cttcgtgaag attactgaga aattgcgcaa tgcgcaagaa
    21721 ttgcttcgca aagatgctga agactttgac tgggaaaatt tgtaagatag gagaccgaaa
    21781 gaatgaaatt tgttggactt gttggatcaa actacgatca atcatataac cgcaaactct
    21841 tggaatttat ccgtcgcaat ttcaaattca aatttgaatt agaagtactt gaaatcgacg
    21901 aagttccaat gtttaaccaa gacgaaaaat gggacgaaag cttccaattg cgtttcttgt
    21961 ataacaagat tacacgtgct gatggtgtca ttatcgccac tcctgagcac aaccacacta
    22021 tctcagcttc actcaaatct gtacttgaat ggctttcata cgaagttcat ccatttgaaa
    22081 acaagcctgt tatgattgtg ggtgcatcat actatgacca aggaacatca cgtgctcaag
    22141 ttcaccttcg taaaatcctt gatgctccag gtgttaatgc ctacacgctt ccaggtaacg
    22201 aattccttct tggtaaagct aaggaagctt ttgataacaa cggaaatatc accaacgaag
    22261 gcactgttaa attccttgaa acttgcttag ataactttgt taaatacgta ggagtcgttt
    22321 cgaaattgaa aaaaccaaaa ccaatcgaat cagaagactt ggattgtgga aaaccaatcg
    22381 ctacaaccat cacagaagtt gaccctgacg atccagaatg ggtagaaaaa gttgcagcaa
    22441 tcactggtgc tgtttctggt gatacctatg tcaaattgga ccacggtatc ctaacagtta
    22501 accaaattga tatgttcttg aaagctatgc catttgaatt gacatacgct gacgacaaca
    22561 accaattcct ctactacaac aacgctcacc aagatccaga cactatgttc gctaaacgtg
    22621 taccacctca atcaggtagc cgtatgtcga ctgttcatgg ttctcttcca ccagcacgta
    22681 tgaagaacgt agagtgggtt atcggaacac ttcgcaacgg aaaccaagaa tacgtccgta
    22741 cgatcgttcc aggttctcct gcaggtgtta tcaacactca caactaccaa gcaatgtact
    22801 atcctgatgg atcatacgct ggtatcaatg aaatcgtctt taacttccaa ccatggcttg
    22861 actggtacct aaaagagact ggtcaacgtt tggtgggtgg tagcggacca tttgctcctg
    22921 ctgccggagg tcatggagac gccgatgcta cttctggcgc ttctgattca ggggatgctg
    22981 gaggccacgg tggtgacgca gacgctacag ccggtgcaag tta
//
LOCUS       DAVAZV010000033        22314 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVAZV010000033 DAVAZV010000000
VERSION     DAVAZV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22314
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.033"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQT46_001262"
     CDS             complement(160..2118)
                     /gene="ftsH"
                     /locus_tag="VQT46_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET2371293.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQT46_001263"
     CDS             complement(2134..2676)
                     /gene="hpt"
                     /locus_tag="VQT46_001263"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET2371294.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQT46_001264"
     CDS             complement(2680..3957)
                     /gene="tilS"
                     /locus_tag="VQT46_001264"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET2371295.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3954..5222)
                     /locus_tag="VQT46_001265"
     CDS             complement(3954..5222)
                     /locus_tag="VQT46_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET2371296.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5342..5710)
                     /locus_tag="VQT46_001266"
     CDS             complement(5342..5710)
                     /locus_tag="VQT46_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET2371297.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5703..5969)
                     /locus_tag="VQT46_001267"
     CDS             complement(5703..5969)
                     /locus_tag="VQT46_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET2371298.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQT46_001268"
     CDS             complement(6027..9536)
                     /gene="mfd"
                     /locus_tag="VQT46_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET2371299.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YQKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPIQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKEFKEENSI"
     gene            complement(9537..10106)
                     /locus_tag="VQT46_001269"
     CDS             complement(9537..10106)
                     /locus_tag="VQT46_001269"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET2371300.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVKYYLQEKNFEKTMQRYNG"
     gene            complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQT46_001270"
     CDS             complement(10177..11292)
                     /gene="ychF"
                     /locus_tag="VQT46_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET2371301.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIIEFRFNV"
     gene            complement(11376..11570)
                     /locus_tag="VQT46_001271"
     CDS             complement(11376..11570)
                     /locus_tag="VQT46_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET2371302.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQT46_001272"
     CDS             complement(11635..12771)
                     /gene="dnaN"
                     /locus_tag="VQT46_001272"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET2371303.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQT46_001273"
     CDS             complement(12930..14291)
                     /gene="dnaA"
                     /locus_tag="VQT46_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET2371304.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYNYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14504..15262)
                     /locus_tag="VQT46_001274"
     CDS             complement(14504..15262)
                     /locus_tag="VQT46_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET2371305.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15320..16501)
                     /locus_tag="VQT46_001275"
     CDS             complement(15320..16501)
                     /locus_tag="VQT46_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET2371306.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16684..17163
                     /gene="rlmH"
                     /locus_tag="VQT46_001276"
     CDS             16684..17163
                     /gene="rlmH"
                     /locus_tag="VQT46_001276"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET2371307.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17207..17280
                     /locus_tag="VQT46_001277"
     tRNA            17207..17280
                     /locus_tag="VQT46_001277"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17241..17243,aa:Arg,seq:tct)
     gene            17445..17570
                     /gene="comC"
                     /locus_tag="VQT46_001278"
     CDS             17445..17570
                     /gene="comC"
                     /locus_tag="VQT46_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET2371308.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17591..18916
                     /locus_tag="VQT46_001279"
     CDS             17591..18916
                     /locus_tag="VQT46_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2371309.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18913..19665
                     /locus_tag="VQT46_001280"
     CDS             18913..19665
                     /locus_tag="VQT46_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2371310.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19717..19788
                     /locus_tag="VQT46_001281"
     tRNA            19717..19788
                     /locus_tag="VQT46_001281"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19750..19752,aa:Glu,seq:ttc)
     gene            19794..19867
                     /locus_tag="VQT46_001282"
     tRNA            19794..19867
                     /locus_tag="VQT46_001282"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19828..19830,aa:Asn,seq:gtt)
     gene            complement(19908..20450)
                     /locus_tag="VQT46_001283"
     CDS             complement(19908..20450)
                     /locus_tag="VQT46_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET2371311.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20629..21396
                     /locus_tag="VQT46_001284"
     CDS             20629..21396
                     /locus_tag="VQT46_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET2371312.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21481..22161
                     /locus_tag="VQT46_001285"
     CDS             21481..22161
                     /locus_tag="VQT46_001285"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET2371313.1"
                     /translation="MADGSGKLAEGGTKLTSGLEDLQTGLASLGQGLGNASDQLKSVS
                     TESKNAEILSNPLNLSKTDNDQVPVNGIAIAPYMISVALFVAAISTNMIFAKLPSGRH
                     PESRWAWLKSRAEINGIIAVLAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMV
                     TTLTTWNSRIGAFFLLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQT
                     ISINKSFS"
BASE COUNT         6901 a         4110 c         3643 g         7660 t
ORIGIN      
        1 acagtccctt ggacttcttc atacaattct ttaatcataa ttttcccctt tctagataca
       61 gtctaacaga ttagaaaaca catttgttcc attttctcca ttctgttccc tttagctcct
      121 aaactgcaca aaaaagagag gctccagcct ctctcagggt tatttttcgt cattcatttt
      181 tgactttact tcatcatagg atagtgcatg agattcctct tctactgctt caggcatctt
      241 tcctgtttcg taaagagctt taatttgtgt actatccaat gtttcgtatt tcaataatgc
      301 ttctgcaatt aacttgtgaa tttcacgatt tgactgaata atttcagcag ctttatttcg
      361 tgcctcattt aataatgaac gaacctcttc atcaatttca taagctgttt gttctgaaat
      421 tgatttttga ggactctgtg caccaaacat agcatggttt ccttcatatt gtactgggcc
      481 aagtttttca ctcataccgt actctgtaac cattgcacgc gccatttgtg tcgcttgttc
      541 aaagtcgttt gaagctcctg tagtttggac attaaagata atttcttcag ctacacgtcc
      601 acccattaag ccagccaatt gctctttcat atcttcttta gatagaagca tttgatcctc
      661 tttaggaagt gcaatcatgt atccgcctgc acggccgcgt ggtacaattg taaccttatg
      721 gacaacgcga gcattcgaca agactagacc aacaatggta tgtcctgcct catggtaagc
      781 aaccaattct cgttcttttt gtgaaactgt cttatctttc ttagaaggtc cagcaataac
      841 tctatcttct gcttcatcaa tatctgaagc atcaattatc gatttattgc gacgagcagc
      901 aactaaagct gcttcattca agacattctc taaatcagca ccaacaaagc ctggagtttg
      961 ttgagccact aatttcaaat caacatcttc tgctaaaggc ttgttcttag cgtgaacttt
     1021 caagattgct tcacgacctt taacatcagg acgaccaacc aatacttttc tatcaaaacg
     1081 tcctggacgc aaaagggcag gatcaagtac atctgaacgg tttgtcgcag cgatgacgat
     1141 aatcccttca tttccctcaa aaccatccat ctcaatcaaa agttggttca aggtttgttc
     1201 acgttcgtca ttacctccgc cgagaccgac tccacgttga cgtccaacag catcaatttc
     1261 atcgataaag atgatagctg gtgctgcttt tttggcatcc tcaaaaagag agcgaacacg
     1321 actagctcca actccgacaa acatttctac aaagtcagaa cctgagatac taaagaatgg
     1381 aacacctgct tctccagcga ctgccttagc aagcaaagtt ttacctgtcc ccggaggtcc
     1441 ctccaaaaga acacctgctg gaatacgggc tccaagtttt gtgaatcgtt ttggatcttt
     1501 taagaactca acaacttcaa ctagttcttg tttttcttcc tcagctccag caacatctga
     1561 aaatcttact ttaatatctt ctttatttgc tgctttagcc ttactacgtc caaaactcat
     1621 tggattacgg ccattgcctc ctcccatatt tcccatcata gagaatagga agaagaatag
     1681 aattccaaat ggcacaatgg atacgagtag attaatccat ataccacttg aactttcatg
     1741 cttaacagtt acttctgctt tatggtcagt agcaagtttt tgcaattctg atacggtagt
     1801 atctgcagga agaatagtgc tggtaaattt ctctacctta gtaacagatg gcgtgaaaaa
     1861 ctgaatacct gtttcttctt tacttgtttt aggattttta tagacaccag aaacttcgat
     1921 aacactacca tttggttggt aagttaattc ttttacatta ccatcggtaa tttcttgtac
     1981 caactcagta tagttgattt gctgacttcc tcctgagtta ttcccagaat agaaatactg
     2041 gaatcctgtc acaaggaaaa agataaataa taaccataga aaaggatttt taattaaacc
     2101 attattttgt tttttcatta aagattattc tttctaattt gaatacactt cctctttcaa
     2161 tactccaata taaggaagat tacgataatt ttctttgtag tctaaaccat aacctactac
     2221 aaactcattt gggatagtaa agcaggtata gtctgcctca atttctacaa cacgtccttc
     2281 tggtttatcc aacaaggttg caattttaac agaagctgct tctcttgctt taaacatatc
     2341 tcgcaaattc ttcaaagttt gacctgtatc aatgatatct tctacaaata gaacatgtct
     2401 tcctttgata tcttgagtca catcttgttt aatattgata acaccactac ttgctgttcc
     2461 accatggtag ctagaaacca tcatgaagtc catttcaata tgtgtatcaa tatgtttgac
     2521 caattcagcc ataaaaggaa tagatccttt taaaatccca actaagattg gattttttcc
     2581 tgcatagtct ttagttaatt gagcacctag ttttttagct gcttctgtaa tttcatcgtg
     2641 tgaaacgagg acttttttaa tatcgttttc taacattttt tacctatcta ttttttctat
     2701 ataaagtaca gtgttcatta tatcattttt cgttttttta ctcaaattat tggtcgcaat
     2761 tcccaaaatt gagacaattt caccaaattg ctcaataata agagcagagt ttctcttttc
     2821 catagggatt ttcaaatcaa taaataaacg tctgagtttt tttctatgcc cattttgaat
     2881 caaaacatct cctgtttttc gatgacgaat gtgtatggat gtttcacgtg aaacaggtat
     2941 ttgttgaatt gattcacctt ctaatggaag tccaaaggaa aataaatatc cttgataagc
     3001 tacctgattt tgatagtgta acacaagttc atcttcctct tcatcagcct gcggactgat
     3061 tttacaaatc tgaaactgtt ggtactcttt tatcaattca tagccatttt taatcggatg
     3121 acgatactgg cttttagatt ttaaaatctg ctgaacttca gcaaactgag cttttgtaag
     3181 attcaaatct ggaaaacgat tcagataagt ttgaagtaaa actctttgtg tagactcaga
     3241 gtaagaaaat aactgctgta aatcttccac attaatattg ttagataatt cagctattgc
     3301 caaatcataa tctaaaattt cattgccaat gcctaagatt gcatccctaa atcgaggatt
     3361 ttctttttcc aattctggta agtaagagtt tcgaatacga tttcgaaaat aatgattctc
     3421 ctgatttgat gtatcttcaa agtgaaaaat tgatggaaag tcttttttct gaaaatgcaa
     3481 gaagggacga atgatttcta tctctccgac tacttgcttc tccttaattc ctgatagata
     3541 gcgcaagcga gttcctcgaa tcaagcgcat caaaatcgtt tccacctgat catcagcatg
     3601 gtgggcagtg actaaagctg tcgcacctgt ctttttcatg acctcttgaa aaaaatcata
     3661 acgaaaattt cgtgcacgcg cttctgaaaa ttctcctgaa aaattgctga tataaatagg
     3721 aagctctgct tcagcagcca acttccttaa ttccttttct tcccaatctg attcaattct
     3781 ctgcttatga ttcacatgag ctagaatcaa ttcaatctct aactcttttt gataagtaga
     3841 caatacctta aatagaaaca tggaatctaa tccaccagaa agagctagaa ccgccttagc
     3901 atgctttttg aaatatccct tcttgagaaa atgatttaaa aaatctggtt ccctcatttt
     3961 agaacctcat aaacatcctt ggctatctta gaaatcgtat cataatcaga attcttagtg
     4021 aaaatagaaa gaataaatgg agaatctgca tagacaacac ccgtatcatg cttaaattca
     4081 tccgcatctc caattttatg agctacttta acagaaacac ctttggcaat tcgctgacta
     4141 tcaaaatctg ttttagtcaa agactctaac acaaatccat tttgattata aatagcttcc
     4201 ataaacttcc cggccatctt agaagaaatc aatttttctt ttggatccca atcatctccc
     4261 ataatggcag acatcttgga tttgaatgtg gcatcagatt ggtttgaaat gtaatatccc
     4321 aatagattat gagctacatt atcagattct tttgatactt tcgtaattaa atcctttaaa
     4381 gaatattctt tattatcttc ttttttagga agactaccac ttccctctgg tttataagaa
     4441 cctggaaaat cattgactgc agatacgtat tttacagtcg tatctaactg ataaagaccc
     4501 tcatttattt tttcttgcgt ataatagaga taagagagtt tcaaaacgct ggctgcatac
     4561 atcttttcat cttgattgat accagcttct tttccagtag tcagttgctt aacataaata
     4621 gagaaagaat ctttctgata tttttcagat aacatttctt gaactttact catccgatta
     4681 tcttcttcag aagttgattc tttagctacc catccagcct gatcaatatg tagaaattct
     4741 cttccttcta caaacatggt cttgtcgatt gatacttgcg aataagctga taaggatgat
     4801 ttcacttctt ttaaatcata aggactattg tacagtttaa agtcagattc taaccatgct
     4861 ttttttattg ttggagttac ctctgattga tcatataaaa atcgtttgtc cgcagctata
     4921 aattgatgat ttgatagctt aaatactgga attccttgtt tatttaagcg ccactcggtt
     4981 atttgaaaac ttgttttggg agtcaatttc ccagattcca ctactaaatc ttcattcgca
     5041 taaacaggaa cctctccata aaccatggga gaacttaatt tttctctaaa ataaatacca
     5101 aagtcagatt gtgaaaggta ataaatttct ttcgaagtat agacgacttc tttttctgtg
     5161 ctaacgactt ttgaaatggt caaaaaactt ggtagcaaca aaataattaa gaatttacgc
     5221 attcttcctt tccttttctt cttgtaaacg caataattga tttttatcag ccaattcttc
     5281 cagcttttca tctgacaaac tcaaaaattg ctctattacg tctaataaat tttccatttt
     5341 atcacctttg aagcaagtca ggaatcgtat aaactttttc cctcgactta gaataatagt
     5401 acttcgctcg tgtatatttg gcagcataat cttcatcttt caacttggta gcaaatgctg
     5461 tctccttatc cttttcatca ctcaaagttt gatactgagt ttgcaagtct gctaattgct
     5521 gacgtctttg gagtaattgc tgataactct gcgctaaatt aaaagttggc aagataaata
     5581 atagcataat caaaatcaat acccctccca taaaacgatt ccgtttttgt cgttctttca
     5641 tcaggtagcg acgacgttgg tattcatttt gaataaaaga attattcaat tgtacaatat
     5701 ttttagacat tttcttctac ccgtgtttca ctgataattt catacattcc tgctgcatct
     5761 tctttttttg tactatcttt catctctagt acttttacaa gcagcaactt attgccaaag
     5821 cgaatttcaa cttggtcatt aactttcaag tccgttgaac ttttggccaa gattccatta
     5881 accttgattc tacctttatc tgctacttcc tttgcgactg tacgacgctt gataattcgc
     5941 gatactttta aatatttatc taatctcatc cttattacct caatttatta ttgtaccatt
     6001 tttatctatt ttatagaaga aaaatatcaa atggaatttt cttccttaaa ctcttttatc
     6061 tctaataaac tttctccaaa aatcagcaga ccttctaaaa tttcataatc tttcttattt
     6121 tggacatcaa atacaagctc cattaatccc ttattctcag cgatgcctgc ttttaagttc
     6181 gttacggata aagctttaaa ataatcttga gctaaaaaca atcgttgagt gactttttca
     6241 aattgaattg taattttatt atcttttctt tccacacgtt gaacaaagac cttgtccaag
     6301 tatgatttaa ccaaaccaat ctctaaaaga taggctacta catctgggta ttctccaaaa
     6361 cggtctatca actcctcttg taactcttca taattgacac ggttgtcaat ttgacgaatt
     6421 ttcttgtaaa tttcaatctt atgtcgttga tcagaaatat aagtatcagg aagataggca
     6481 tcaatttgca aaatcaactc agcattccct ttggttcttg tgttagcgtt agcattaccg
     6541 tttcgtttag caatagcttc ctctaataac tgcgaataca attcaaaacc aacagaatca
     6601 atgaaaccag actgggattt tcctaaaaga tttcctgctc cacgaatcga aagatctcgc
     6661 attgcaatct taaagccaga gcccaattct gtaaatcctt taatcgcttc taatctcttt
     6721 tcagagactt cactgattga tttttctgga cgatacatga gataagcata agcaatacga
     6781 ttactacgac cgactcttcc tcttaactga tataaggttg acaagcccat atggtccgca
     6841 ttttcaataa ataaagtatt agcatttgga atgtccaccc ctgtctcaat aatagtagtc
     6901 gtcaccaaga tatcgtattg tccctcaata aagtctaata gagtattttc caactggact
     6961 tcactcattc gaccatgaac atatccaatc gaagcctccg gaatcaactc ctgtaattct
     7021 gaaaccttct gaacaattgt gtcaactttg ttgtaaagat aataaacttg acctccacgc
     7081 tccatttcac gcaagacagc atcacgaatg acactatcat tcttttccaa aacataggtc
     7141 tgaacaggat agcgattagt cggcggagtt tcaataacag ataaatctct gattcccagc
     7201 atagacatat ggagggtacg agggattggc gtagcggtca aggttaggac atccacttgt
     7261 ttcttcagtt ctttcaaagt ttccttatgc ttgacaccaa atcgctgttc ctcatcaata
     7321 atcatcaagc ccaaatcagc aaacacaaca tcttttgaca aaacacgatg tgttccaatc
     7381 aaaatatcga cttgaccgtt tttcaatttt tcaagtgttg cagtctgctc ttttttactt
     7441 ctaaagcgac tcaacacatc aatattaact gcaaaatttt ggaatcgttc cttaaaattc
     7501 gtatagtgct gttgcgctaa aaccgtcgtc ggaactagaa tgacaacctg tttgtgatca
     7561 ttgactgctt taaaggctgc acgcatagca acttcagtct ttccaaaacc aacatcccca
     7621 actaaaagtc gatccattgg ctgagaagcc tgcatatccc tcttgatttc ctcaatacta
     7681 cgaagttgat catccgtttc aacataaggg aaagcatcat caaaggcatc ttgatcatca
     7741 tcatcagctg agaaagcaaa acccttcaac tgactacgtt cagagtagag tttgattaaa
     7801 tcatcagcta tatcctctac ctggttctta accttttgct tggccttttt aaaatgaccg
     7861 tcatttaatt tattgagttt tggagcttta ccatcacttg aaatatattt ggacagtaga
     7921 tgaatctgtt ccacggggat agaaatttga tcaccatttt ggtattggac actgacataa
     7981 tcgcgatgaa ttcccttgat ttcaatggtt tcaattccta gatattgacc aatcccatgg
     8041 atatgatgga caacatagtc ccctttttca agttcattgt aatcttttaa tctctctgca
     8101 tttgaaacat gttgtcttcg aaaacgacgc tttaatttct tttgaaaaat ctcatgttca
     8161 gttatcaata aaatcttttc atctacaaaa tgaaaaccat gtctgagatt accctctatt
     8221 aaatttacag attctttaca gatacttgtc ttatctctag aatccaattt aatctgatat
     8281 tcctctaaca tatcctccaa tgttttactt cccattgaat tgctagactg cagaataatg
     8341 gtgtaatcca tttttttata tcgttcaatt tcttctttta gaaaagaaaa ctgattgaaa
     8401 aattcctgta taggatattg attgaattga taaattttgt caaatttgag atttcctaaa
     8461 cccttttgaa gattagagaa aaaggtcact ggactttgtt ttttatagat ttgttcaata
     8521 tcagaaaaat actgcatatc agaaaatgct ttactattct gtaattcttc tgtaaagtac
     8581 tgcgctaatt ctctttcaaa gacttcatac tgattcatca atttttgata atcatcaaag
     8641 aatattggag tatctttttc aatataatca aagacagtcc atgtcttatc atagcacaaa
     8701 gataaaaact tccgagaatc tgcatgactt tgtttttggt gaaaacttga aagaatttct
     8761 tctaggtatg atttcaaaat aggtgataaa gtttttgaaa tttgtttttc taaagctgac
     8821 tgtcctcgtt gataatcctt ttctctcaaa agcatatcac tagctggaaa gatagtgagt
     8881 tctgtcttat tttctttcga taattgtgtt tctacttcaa atgacctgat accatcaatt
     8941 tcatcaccaa aaaactcaat tcgacaaggt tctaactggg atatttcaaa aatatctaaa
     9001 atatctcctc gaagactaaa ttcgccctga gtttgtactt gagtaacttt ttgatagcca
     9061 ttttccttta actgatggat aaacgcgtgt tgagcatatt cttcaccaac tgagattttt
     9121 acaatactat ctttgaatgc attgggagac ggtaaaatca atcgacttgc tgcgatatta
     9181 caaactaaaa tccctttctt agatgaatca gtcaaaaaac gcaaggcttc aacccgtgaa
     9241 ataatttttt cctgtgaaga catcaaaaac tccaccatag gagcatcatc taccaaaaat
     9301 ggatagacga gttcctcacc caagatagaa ataagatcac taacaagtcc ttctgcttct
     9361 ccataagttg acgtcaataa cacaatccta tcttcttttt ctaaactgct tgcaattgca
     9421 agagccttag tagatgttga taaaccaagt attagttgtc ttttcttatc tgttaaattt
     9481 tgatgccatt ttttaatctg atcattttct gagaataaat ctaataaggt caccatttat
     9541 ccgttatacc tctgcattgt tttctcaaaa tttttctctt gtaaatagta ttttacagaa
     9601 tcgtcaactt tgtcaacaga ctgtaaaata ccgatataat catccctgtc aaacttactc
     9661 aaaacatgat gaacaactga cataccattt ttaggtcttc caattccaat cttaacacgg
     9721 ttaaagacct gagttcctat atgttgaata atagacttga taccattatg accacctgct
     9781 gagccttttg ctcttaaacg aattttccca acttccatgt caagatcatc gtaaatgata
     9841 agtaaatcgt caatatccaa accatagtaa gttaataaag catgaactgc ttttccactt
     9901 tcattcataa aggtcgttgg tttaaccaga taaatttttt ctccatttag gaaaaaggat
     9961 gctaggtcag cttgaaatat cttatcgtgt gtaaaagtga cattctgttt cttcgctagt
    10021 tgatcaatca acataaaacc aacattgtgt tttgtttcaa aatatttatc ccctggattt
    10081 cccaaaccta caagtaattt ggtcatttat ttttcctttc aaaagccaaa agggttggaa
    10141 tttttttcca acctaattga caccatttat taatttttag acattaaagc ggaattctat
    10201 gatgtcgcca tcttgaacga tatattcttt tccttcttca cgcaagcgtc cagcttcttt
    10261 tacggccttt tcagatccgt atttcactag atcttcatat gacatggtta ctgcacgaat
    10321 aaagcctttt tcaaagtctg agtggataat accagctgct tgaggagcct tcataccacg
    10381 tttgaaagtc caagcgcgaa cttctttttc accagctgtg aagtaagttc ccaatccaag
    10441 caagtggtaa gctgcacgcg tcaacttatc tacacctgat tctgtcaaac caatggcttc
    10501 aagaaactct tttttatctt catcatccaa ttcagaaatt tcttcctcag cacgcgcaga
    10561 aataacgact acttcagcat tttctgtcgc tgcaaattca cgaatttgtt tgacatagtc
    10621 gatagagtca ggttctgaaa ccacatcctc gtccacatta gctacataaa gaactggttt
    10681 agtcgtcaaa aggaaaagac ctttgacaac cttttgttcc tcatctgtaa attcaatggt
    10741 acgagctgat ttcccgtctt ctaggactgg tttaatcttt tgaagaacat tgaattctgc
    10801 tactgattct ttatcttttt gcgtacgtgc catcttttct acacgcgcat atcgtttgtt
    10861 cactgattct aagtcagcaa gaattaattc cagattaatt gtatcaatat ctgcaagtgg
    10921 atctacaaag gcgtcttcac gtccttgctc gcgcatcaca ttttcatcat caaaagcacg
    10981 aactacgtga acaatcgcat ctacttcacg aatattggcc aagaatttat tccctagccc
    11041 ttctcctttt gaagctcctt ttacaatccc tgcaatatcc gtaaattcaa atgttgtggg
    11101 aactgtcttt ttaggagtta tcatttcagt tagtttttgt aggcgttcat ctggaacttc
    11161 caccattcca acatttggat caatcgtcgc aaatgggtag tttgctgcct ctgctcctgc
    11221 ttttgtaatt gcattaaata gtgttgattt accaacgttt ggcaaaccaa cgatacctgc
    11281 tgtcaaagcc atatttctca ttctccgttt tcatttcaat ccctaatatt ataacacaaa
    11341 aagggataaa gtgctaaccc tctaactaag ggttctcagt caataatttt attcattttt
    11401 cgctcaaaat catatcgccc catcatgaca acatgctcac aattactgca ttttattttg
    11461 atatctgctc ctacacgtgt aatttcccaa cgattagcct ttttaccagt cgacttgatt
    11521 gtacaagcgt gtgatttttt catctcaaca aaatttccaa cttgatacat actactctcc
    11581 ttttcttttt cgattatatc ataaaagagg cgagccaggc tcaacctctt tcacttaatt
    11641 tgtacgaact ggtgtaatga gctgcatgaa gtcttcgtca gtatctgctg gcacaagagt
    11701 aaatggacga acagctgaga taaagctaat ggtcaccttt tcgctattta aagctttaag
    11761 agaatcaatc aagtaagttg ggttgaaact aatggtcaaa tcttcaccag taacctgatc
    11821 agtatcgatt tcttcgttta ctttaccaac ttctggagag tgaacatggg cgctaacaac
    11881 cccatcctta atttcaagtt tcacagtacc attttgagtc gcacttgata aaagacgggc
    11941 acgctccatt gactggcgta agtttaccac attaaaagta atagtagtgt taaagtctgt
    12001 tggaatcaag cgatctgtat caggatagtt tccttctagg agacgagtat agaagctaat
    12061 attttcgctt ctaaagagga tttggttatt ggcaaagaaa atctctacag tttcgatatc
    12121 atctgtaaat accgctgaaa attcgcgtag agaacggcta ggaattacga catcaaaatc
    12181 atcactattt ttttcaagag tcaatttttt ctggcttagg cgatgagagt ctgttgcaac
    12241 tgtttttaac tctttgtgtt gactcaatac gaagtggaca cctgttaaaa tcggacgact
    12301 ctcttgtgta cttgcagcaa aggctgtttc attaataatt ttcttgagta attttgtttc
    12361 aagtattaaa ggagtgcttg ctgaaatttc ttggattcgt ggatattgtt cgctatcttt
    12421 tccttttagg gtaatttctg atttgccact ggttaaaaca atttgatttt gttcaatttc
    12481 tttaaaatca agagttacat caggtaaact agatactaca ttgataaaga aagaagcttc
    12541 aagaaggatc gaacctaaag aagtaattaa caaaccagca tcttcatttt tttgagaaat
    12601 aaaattttca attgaaattt gaccatttga accaattaaa gtaatacctt cattggtcac
    12661 gtcaattttt actgttgata aaataggaat ggcattttta gaactaatag ctctcttagt
    12721 agtatttaat gcttgtagaa ataaattttt attaattgaa aaatgaatca tggattctcc
    12781 tttatttatt tttagtatta gaaagataat agtaataata gagtctgtga aatctgtgga
    12841 aaacagcctt taaacaagtc atatcaagtt ttttagcttg tttaaaaaat gtggataaaa
    12901 aagataaaaa actaaaagtt atccacaaat tatttgattt tctttttgat tgattcaatt
    12961 tctaaacgta aattatcgtc ttgatcaatc aaagatttta ttttggcatg ggcatgaatg
    13021 actgtggtat gatcttttcc cccaaattcc ttcccaattt ttggaagact attatctgtt
    13081 agttctctag ataaatacat ggctacttga cgggccaaaa caatattttg aaggcgtcta
    13141 cttcccttca tttctttgat actaacacca taaaagttac caacttcagt ttggatttta
    13201 tcaattggga tgacgagcat ttggctaaca tcttgtttgc gggctctaat ggcttctgca
    13261 gcaatatcaa tagtgatatc cttgattttt tttactctgg caattaaagt gatgtcgttg
    13321 atggctccct caagatctcg aacatttgaa tcaaattgcc cagctaggta ttctagagta
    13381 tcactttgga aattgtagcc taaatgttcc gttttacttt gtaaaatggc aatacgtgtt
    13441 tcaaagtcag ggggtgtgat agtttgtgtc aatccccaac taaaacgcgt gacaagcctc
    13501 tcctcgagcc cttctagatg ttttggacta cgatcactcg ttaggacaat ctgtttttgc
    13561 ttgtcatgaa gggcgttaaa ggtattgaaa aattcttcct gagttgcgac tttttttccg
    13621 ctgagtgact ggatatcatc gattaacaaa agatcaagac tacgataggt ctttttaaac
    13681 ttttccattt ccccaagtct taggtgatca agaaagtcat taataaagct ttcggcaggg
    13741 atatatttaa cacgcgcatt aggaatattt tttagaattt catttccaat agcgtttaat
    13801 aagtgagtct taccaaggcc tggtcctcca tagataaaaa gagggttata ggtcagagcc
    13861 aaatcttcag agacagctaa agcggctgac acagcccaaa catttccatc cccttgaata
    13921 aagttatcaa aggtatactt ttcttttaat cccgtatctg aataaggaat agatactaac
    13981 tttggactat agttataaag agttaaattt gtagcttctt caacttgtga gctagtcgta
    14041 tcttgaggtt tggtgaaaat atagtgggga gttatttcag cgtcataaat ttcaaaacca
    14101 gctactacaa taatatcttt tagttgtttt tcccagacca tttccatttc agagcgaggt
    14161 agaaatatag tggcaacatt ttcctctacc ttgatgagtt cagcttgaat agcatagaaa
    14221 tcatacatgg atcgagtcag tctttcttgt gcaaattcta atatacgatt ccaaaattgt
    14281 ttttctttca atcctttctc ctcctttact atttaaaagt ttaatactag agatatttta
    14341 ccatagatag caagaatttt ccacaagctg tgaaaaataa tccacaatgt taccaaactt
    14401 tatccacagg ttggggataa aagaagaaat tattgattta ttaagctttt tattgaaaaa
    14461 catagtggat aaccttgtga gataaaaaaa taaaagaaca gccttatttc aggctgttga
    14521 taattctact atattcttct tgatttgaaa aagaaataat gatttttcca ctgtcttttt
    14581 tagatagttt aatttctaca tctaatccga gtagttttct taactgtttt tcttcatttt
    14641 gtatgaaatg attagttttt tgctgtttct tttgtttttt ctctgtcaga agagcttcta
    14701 atttccttac agaaatatct tcttctataa tccgttgaaa gaaatagtct tgttgttcct
    14761 tatttaaccc aactagggaa cgcgcatggg cttgtgatag tttgccattt tctacttctg
    14821 aaagaatctg ttctggcaag gaaagtaaac gaatggagtt gctgatatat ggacgagact
    14881 tgcccatctt atctgcaatt tcagcatggg tgaatccttt ctctacgaga gattcatagg
    14941 cgcgtgcttc ttctattggg tttaaatttt ctctctgtaa attttcaata atggactgga
    15001 ccatcatctc ttggtctgaa atctgtttaa caacagctgg gatagaccgt agaccagcta
    15061 aaagtgaagc ccgatagcgt ctctctcctg caaggatttc ataaccaata acaggagatt
    15121 gacgaacaat aatcggttga atgaccccat tttctttgat agactgtgct agttcatcta
    15181 gtttttctct atcaaattct tttcggggtt gatagggatt tttttgtata tctgtgatag
    15241 aaatcatttc aaatttttcc atgattctac actaacacat cttttctctt atgtaaagct
    15301 ttctttacat agatgtcaat taagattcta aatcacctga actcttgtta agtttgatag
    15361 aggtagtttc ttctttcccg ttacgatagt aggttatctt aatggtgtct ccgatagaat
    15421 ggttgtaaag agcactttgt aagtctgttg atgaagcaat ctctttgtca tctacttttg
    15481 taattacatc gtatttttca aggtgaccat tggcaggcat attactttgt accgaacgaa
    15541 caactacacc agatgtaaca ttacttggaa tattgagtct tctgatgtcg cttgtactca
    15601 cattagataa attaaccatc tggattccca aagctggacg cgtcactttt ccgttttttt
    15661 ctaactgttc aataatattg atagcatcat ttgcaggaat tgcgaaacca agaccttcta
    15721 cagatgttcc tccatttgta gcaattttac ttgaggtaat tccgataacc tgcccttgaa
    15781 tattgatcag tgggccgcca gagttacctg ggttaatagc agtatcagtt tggatggctt
    15841 ttgtagaaat agcttgtcca tcttccgatt ttaaggatac atttctattg agactggata
    15901 cgataccttg agtgacagta tttgcatatt cagaacctaa cgggctaccg atggcaatag
    15961 cagtttctcc tacagttaac ttactagaat caccaaactc agctactgtt gtcacttttt
    16021 ctgaagagat ttttacgaca gcaatatcag agaaagtgtc agctccgaca atttctccag
    16081 gtactttagt cccatctgac aatcgaatat ctactttgct ggcgccattt ataacgtgat
    16141 tgttggtgac gatgtaagct tctttatcat tctttttata aataactcca gatccttcac
    16201 tagagattcg ctgagaatct gtgtcagtat catcattgcc aaatacgcta ttttgtctgt
    16261 ttgccgaata agtaataaca gaaacaacag catcttttac tttgttaaca gcctgtgttg
    16321 ttgaattttc gttcttatag gcagtttgtg taatagtact attgttgtta gagttgttta
    16381 cactactttt ttgagttagt tgagttattg aaaaactacc caaggctcca ctaaaaaagc
    16441 taatgacgat aacgactaat aattgaaacc attttttgta aaatgttttt agatgtttca
    16501 tatttgcctc catatgtttg aattactgaa agtataaact gactagctta attataactt
    16561 aaacacaaaa gttttacaca aactgtggat aactcttttg aaactgtgat tttcttaatt
    16621 gaaatctatt ttttattttg tgaataagat gtgaaaaaat agagaatatg ttagaataga
    16681 gtcatgaaaa ttaaagttgt aacagttggg aaactgaaag aaaagtattt aaaagatggt
    16741 atcgcagagt attcaaaacg aatttctaga tttgctaagt ttgaaatgat tgagttatca
    16801 gatgaaaaaa caccagataa ggccagtgaa tcagaaaatc aaaagatttt agaaatagaa
    16861 ggtcagagaa ttttatcaaa aattgctgac cgtgatttcg ttattgtgtt agccattgaa
    16921 gggaaaactt tcttctcaga agaatttagt aagcagttag aagaaacttc tataaaagga
    16981 ttttctactc ttacttttat tattggggga agtttaggat tgtcatcatc tgtaaaaaat
    17041 agagccaatc tttctgtcag ttttggtcgc ctaaccttac cccatcagtt aatgagacta
    17101 gttcttgttg aacaaatcta tcgcgctttt acgattcagc agggattccc ctaccataaa
    17161 tagaaaattg acttttaatt gaatttttgg tagaataatt gtattaggtc tcatagctca
    17221 gctggataga gcattcgcct tctaagcgaa cggtcgcagg ttcgaatcct gctgggatca
    17281 atataatagc aaagctggga attttcccgg cttttttctt aaaaaagtac actttgggag
    17341 aaaaaaatga cagttgagag aattttatct aaaacgaaat tccattttgt ataatggttt
    17401 ttgtaagtta gcttacaaga aaaaacattt taggagattt tattatgaaa aacacagtta
    17461 aattggaaca gtttgtagct ttgaaggaaa aagacttaca aaagattaaa ggtggggaga
    17521 tgaggttgtc aaaattcttc cgtgatttta ttttacaaag aaaaaagtaa tgaaataagg
    17581 ggaaagagta atggatttat ttggatttgg gacggttatt gttcattttt taattattag
    17641 tcacagttac cattttattt gtaaaggtca aataaataga aaagaattat tcgtttttgg
    17701 tgcttataca ttactaacag aaatagtatt tgattttccc ttatatattc tatatttaga
    17761 tgggttaggg attgaaagat ttttatttcc tttgggatta tattcctatt ttcgatggat
    17821 gaaacagtat gagagggata gaggactatt cctaagttta ctactatctc ttttatatga
    17881 gagcactcat aactttctgt ccgtaacttt ctcctctata acaggagata attttgtttt
    17941 acaatatcat ttcccattct ttttcgttgt gacggtgtta acctattttg ttacattaaa
    18001 aatcatttac tatttccatt tggaactagc ctattttgac gaggactacc tttatccttt
    18061 cttgaaaaaa gtattttttg ctttactatt gctacatatt gtatctttcg tttcagatat
    18121 ggtaagtacg attaaacatt tgaatagttt tggaagtatt ttgtcatcta ttgtctttat
    18181 ctctctcctt ttgaccttct ttgcaatgaa ttctcataaa gttcaaatgg agaaagagat
    18241 tgctttgaag cagaagaaat ttgaacagaa acatttacag aattacacag atgaaattgt
    18301 tggtctgtat aatgaaatcc gtggttttcg acatgattat gctggaatgc ttgtcagcat
    18361 gcagatggca attgacagtg gtaatttaca ggaaattgac agaatttaca atgaagtttt
    18421 agtcaaagca aatcataaat tgcgttcaga taagtacact tactttgatt tgaacaacat
    18481 agaagactca gctttacgaa gtttggttgc tcagtcaatt gtctatgctc gaaataatgg
    18541 tgtagagttt acactggaag taaaagatac gattaccaag cttccaattg aactattgga
    18601 tttggttcgt atcatgagcg ttttattgaa taatgctgtc gaaggatcgg ctgatagcta
    18661 taaaaagcag atggaagtag cagttattaa gatggaaact gaaacagtta ttgtgattca
    18721 gaattcatgt aaaatgacga tgactccttc aggagatcta tttgccttag gattctccac
    18781 taagggaaga aatcgcggag tcggattaaa taatgtgaaa gaactactag ataagtacaa
    18841 caatattatt ttagaaacag agatggaagg cagtacattt agacaaatca ttagatttaa
    18901 gagggaattt gaatgaaagt tttaatttta gaagatgtta ttgaacatca agtgagacta
    18961 gagagaatat tggatgaaat ttcgaaagaa tcgaatattc caatatcata caagacaacg
    19021 ggaaaagtcc gtgaatttga agaatacatt gaaaatgatg aagtaaatca gctttatttc
    19081 ctagatatcg atattcatgg aattgagaaa aagggatttg aagtggctca gctcattcgt
    19141 cattacaatc cttacgctat tatcgtcttt atcactagtc gatcagagtt tgcgactcta
    19201 acctataaat accaggtatc agccctagat tttgttgata aggatatcaa tgatgagatg
    19261 tttaagaaga gaattgagca aaatatcttc tacacgaaga gtatgttact tgaaaatgaa
    19321 gatgttgtag attatttcga ctacaattac aagggaaatg atttaaaaat tccttaccat
    19381 gatattttgt atattgaaac aacaggggtc tctcataaat tgcgcattat tggtaagaat
    19441 tttgcaaaag agttttatgg taccatgaca gatattcagg aaaaggacaa acatactcag
    19501 cgattttatt ctcctcacaa gtcatttttg gtaaatatag gcaatatcag agaaattgat
    19561 cgaaaaaact tagaaattgt tttctatgaa gaccatcgtt gtcctatttc aagattaaaa
    19621 attagaaaat taaaagatat tttagagaaa aaatctcaaa agtgattgac aattagcaag
    19681 aaattgatat aatggttata tctgctacag atagaaggtc cgttggtcaa ggggttaaga
    19741 caccgccttt tcacggcggt aacacgggtt cgaatcccgt acggactatt ttatccgcca
    19801 tagctcagtt ggtagtagcg catgactgtt aatcatgatg tcgtaggttc gagtcctact
    19861 ggcggagtat agataaaagg gaacacagct gtgttcctct ttttgtatca atttgtatca
    19921 ccaagcattt tcataaggaa gtctgttatt tcttgagaac tttctttttt tccatgtgca
    19981 atccaagttt ggcagacacc aaaaagtgca tgagttagat agatgctact atattctaat
    20041 tcggtggtat ttagattcag ttgcataaat cgcttttgta aatctgtact aagcatgata
    20101 tgaagtttat ttcgtaagaa attttggatt tctttagtcc cattttcaga aagaagggca
    20161 gccagaagtg gttctgactc tagatattca aaaacttcta aaatagcgtc tcttttgtga
    20221 tgagcatgtt tttgaaaaat atattcaaat gtatggaata gcttgctttg atagtgctca
    20281 atcatatcat acttatcctt atagtgagta tagaagctgg aacgactaat tccggctttt
    20341 tctactaatt tgacagtaga aattttatca aatggctgtt ccatcagtaa ttgtaccata
    20401 gcattttcaa tagttcgctt tgtttttaag cgtttgttac tttcttgcat atttcctcct
    20461 tgtaaacaaa ttagactata tgtttaaaaa tagatttttt atcttgtaat ttagattttt
    20521 taatgtataa tctattatat caaaatttta gacaatatgt ttaaaaaagg agaaactaag
    20581 tttaaagaat ggaaagcaat ttaaaaaaaa ccaaccttta ttattgtcat gatcgggatt
    20641 tctcttattc cagatctgta caatatcata tttttgtcat caatgtggga tccatatggg
    20701 caattgtctg acttacctgt ggcagttgta aataatgata aagaggcttc ctataatggt
    20761 aatactatgg caataggaaa agacatggtg tccaatttaa aagaaaataa aaccttggat
    20821 tttcattttg tagatgaaga ggaaggaaag aagggattgg aagatggcga ttactatatg
    20881 gtagtgactt taccaagtga tttatctgaa aaaacaacta cattatccaa tattcaatcg
    20941 acagcagctt atcaatcatt gacaagtgag caacaaactg agataagtga ttctgtatct
    21001 caaaattcaa ctgatagtat tcaatcggct cagtcaattg tagctttagt acaagattta
    21061 cagggaagtt tagaaaactt acaaaatcaa tcttctaatc tttcgacttt aaaaaatcaa
    21121 tctaatcaag tatcacctat tacttctact tctttgatag gattgtcaag tggattaaca
    21181 gagatacaag gagatgttac tagcaaatta gttcctgcca gtcagtcgat tgcatcaggt
    21241 gtaaacgcat atactacagg tgttgataaa gtttctcagg gcgcaagtca actaagtgaa
    21301 aaaaatgcca ccttgacagg tagtttggat aaactagttt caggctcaaa caccttgaca
    21361 caaaaatctt ctagattgac agcaggagtt ggttaattac aatcaggatc tgggcaatta
    21421 gcagacaaat ccagtcagtt actttcaggt gcttctccat tagagaatag agctaataaa
    21481 ttggcagatg gatctgggaa actagcagaa ggtggaacaa agttaacttc tggattggaa
    21541 gatttacaga caggacttgc ttctttagga caaggactag gtaatgctag tgatcaactc
    21601 aaatcagtat caacagaatc taaaaatgca gagattttgt caaatccact caatctttca
    21661 aaaacagaca atgatcaagt tcctgtaaat ggaatcgcaa tagctcctta tatgatatca
    21721 gttgctcttt ttgttgcagc aatatcaaca aatatgatat ttgcgaaatt gccttcagga
    21781 cgtcatccag agagccgttg ggcttggttg aaatctcgag ctgaaataaa tggtattata
    21841 gctgttttgg caggaatttt ggtatatgga ggagttcagc ttattggttt aactgctaat
    21901 catgagatga gaatatttat tctcatcatc ctaacaagtt tagtattcat gtctatggtg
    21961 accactttaa caacgtggaa tagccgtata ggagcttttt tcttacttat tttgctttta
    22021 ctacagttag catcaagtgc aggtacttat ccacttgctt tgacaaatga tttctttaga
    22081 tctattaatc cctggttacc aatgagctat tcagtttcgg gattacgaca aacaatctct
    22141 atcaacaagt cattttccta gctgtcatac tagctctatt tactggttta ggtatgctag
    22201 cctatcaaca taagaaaatg gaagaagatt aaaaaaatcg accgattaat gaactgcacc
    22261 ccaaaagtta gacagaaaaa atctaacttt tgaggtgttt tattatgaaa ttaa
//
LOCUS       DAVAZV010000034        22017 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVAZV010000034 DAVAZV010000000
VERSION     DAVAZV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22017
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.034"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..233
                     /locus_tag="VQT46_001286"
     CDS             51..233
                     /locus_tag="VQT46_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2371314.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIVSELVAGLR"
     gene            533..1372
                     /locus_tag="VQT46_001287"
     CDS             533..1372
                     /locus_tag="VQT46_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET2371315.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGIIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            1390..3228
                     /locus_tag="VQT46_001288"
     CDS             1390..3228
                     /locus_tag="VQT46_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2371316.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPDVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     NLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            3241..4656
                     /locus_tag="VQT46_001289"
     CDS             3241..4656
                     /locus_tag="VQT46_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET2371317.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSAIPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDELNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            5248..6294
                     /gene="pheS"
                     /locus_tag="VQT46_001290"
     CDS             5248..6294
                     /gene="pheS"
                     /locus_tag="VQT46_001290"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET2371318.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            6294..6803
                     /locus_tag="VQT46_001291"
     CDS             6294..6803
                     /locus_tag="VQT46_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371319.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            6880..9285
                     /locus_tag="VQT46_001292"
     CDS             6880..9285
                     /locus_tag="VQT46_001292"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET2371320.1"
                     /translation="MLVSYKWLKELVGIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEILSCEDVPETHLHVCQVNVGEEEERQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKKFADGIQILPENAVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMRGVAHEVAAIYDKAVNFKEFTLTETNEAATDALSVGIETDK
                     APYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SHVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLSRQVRTIAE
                     GAGLTEIITYVLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLEVTYTATAEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSVIEAALQPAAPFVEITKFPAVSRDVALLLKAAVTHQEVIDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEKKVNA
                     EVR"
     gene            complement(9458..10459)
                     /locus_tag="VQT46_001293"
     CDS             complement(9458..10459)
                     /locus_tag="VQT46_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2371321.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMAAILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIADDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            10615..11103
                     /locus_tag="VQT46_001294"
                     /pseudo
     CDS             10615..11103
                     /locus_tag="VQT46_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            11187..11453
                     /locus_tag="VQT46_001295"
     CDS             11187..11453
                     /locus_tag="VQT46_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371322.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGVSQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
     gene            11714..13963
                     /gene="metE"
                     /locus_tag="VQT46_001296"
     CDS             11714..13963
                     /gene="metE"
                     /locus_tag="VQT46_001296"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET2371323.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            14027..14893
                     /gene="metF"
                     /locus_tag="VQT46_001297"
     CDS             14027..14893
                     /gene="metF"
                     /locus_tag="VQT46_001297"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET2371324.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            15578..17791
                     /gene="pnp"
                     /locus_tag="VQT46_001298"
     CDS             15578..17791
                     /gene="pnp"
                     /locus_tag="VQT46_001298"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET2371325.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDDQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRLELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            17807..18424
                     /gene="cysE"
                     /locus_tag="VQT46_001299"
     CDS             17807..18424
                     /gene="cysE"
                     /locus_tag="VQT46_001299"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET2371326.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFIW
                     KHGFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            18436..19320
                     /locus_tag="VQT46_001300"
     CDS             18436..19320
                     /locus_tag="VQT46_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371327.1"
                     /translation="MIQVRNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHIEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            19402..20745
                     /locus_tag="VQT46_001301"
     CDS             19402..20745
                     /locus_tag="VQT46_001301"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET2371328.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYEVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEGLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            20738..21124
                     /locus_tag="VQT46_001302"
     CDS             20738..21124
                     /locus_tag="VQT46_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET2371329.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLISLMLEEQILTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            21128..22012
                     /locus_tag="VQT46_001303"
     CDS             21128..22012
                     /locus_tag="VQT46_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET2371330.1"
                     /translation="MRAKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDMIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
BASE COUNT         6765 a         3964 c         4861 g         6427 t
ORIGIN      
        1 accccaaaag ttagattttt tctgtctaac ttttggggtg tagttcacag ttgaagagcc
       61 agaaaattaa agtgtctttt actcaatcaa aaatagtaac gcctattctt ttggtgaata
      121 agactattgt ttggtatggt gcaatgccat tattagggaa ggtagatgag atgaccatat
      181 tacgtttgga atcagctagt atagtttctg aactagtggc aggtttacga tagagaaaat
      241 ttttaaaaat ttctatgtat gattttcatt tctttagtga gactgttgcc attatcacat
      301 tcgaatcaca caaaataaaa aaatttctac aagtacttga caaatagatt gaaatatcat
      361 aaaatgaaaa tggttacaga gttattaatt atttaagctt catgtcacca ttaaaaattg
      421 aaataaaagg atgttatcac taatacaagt gagcaggaac ctatttaatc acatcggaag
      481 aagtttcttg atgtttttaa gtaggttcct tttattttaa aagggaaatt ttatgatcat
      541 aaaacgaata ctaaaccaca atgccgtaat tgcgcaaagt aaaaaagata tcgatattct
      601 tctttttgga aggggcatag cttttggaag aaaaactgga gataaagtaa atccaattga
      661 tattgagaaa agtttttttc tcaaaaatag agataatatg acccgtttta cagagatgtt
      721 tattaacgtt cctttggagt tggtgtacat caccgaaaaa ataattaacc taggtaaaat
      781 aacattgggt aataattttg atgaaattat ctatattaat ttaacggatc atatttcttc
      841 gagcatagaa cgttataaag aagggattat tatttcgaat cccctacgct gggaaatatc
      901 gaaatattat aaagaagaat ttgaacttgg gaaaagggct ttacaaataa taaaaaaaga
      961 gttaggtatt gaacttccaa ttgacgaagc tgcattcata gcgctacatt ttgttaatgc
     1021 taatttagaa aataattttc aagagtcgta taaaatcact gaaataatta tgggaattga
     1081 gaaaatcatt caagatttct attgtactga gtttaaccaa gattctattg attattatag
     1141 attcataact catataaaat tatttgctca tcgcttggtt gaaaatacaa cttattgtga
     1201 cgatgatgat gaagacttgt tagcattaat gaaaaataaa tatcctagag aatatgaatg
     1261 tggtgaacag gtggcaatgt ttatacaaac tgagtacaat tatttgctga cttctagtga
     1321 attagtttat ttgatggctc atattcgtcg cttaacaaaa aatttagatt aatagaatag
     1381 gagaatacca tgagttataa agatacggta caaaaaatcc tcgatgtaat tggaggtgaa
     1441 aaaaatgtca atagagttac ccattgtgta acacgtttaa gattagaatt aaaagatgaa
     1501 aatttagtca atgatgatga tgtgaagaag ataccagatg taataggtat tatgaaaaag
     1561 aatggacaat atcaaattat acttggtaat gatgtagcta attattataa agaattcgtt
     1621 aaacttggca attttgaatc cgattcagtt gttcaagggc acaaagggaa tattttagaa
     1681 agaatcattg agtatatcgc tggttccatg actccaatca ttccagcaat gttaggggga
     1741 ggtatgttga aagtcttggt aatcatttta ccaatgcttg gtatattgca atcagattct
     1801 cagactattg cttttttgac attttttggg gatgctccat attatttctt accgctgtta
     1861 ttagcttatt ctgcatcaca aaaattaaaa gtaacatcta cattagctat gtctgtagca
     1921 ggtgtacttc tccatccaaa ttttgttcaa atggtgcaat cagggaatcc tcttagttta
     1981 tttggtgcac ctgtgacacc agctagttat ggttcatcag tcgttccaat tcttattatg
     2041 gtttggttga tgaaatatat tgaaaaaata attgctaaat taacaccagc tattactaag
     2101 agttttttgc aacctacgct agtattatta gtatcaagct gtattgcctt agttgtagtc
     2161 ggacctattg gagtaattgt tggtgaagga ttatcaaatc tagttgggca aatgtatggt
     2221 gtagctggat ggcttacatt agctattctt ggtgctatta tgccatttat tgttatgact
     2281 ggaatgcatt gggcttttgc acctattttt ttggcggcat ctattgctac tccagacgta
     2341 ttaattcttc cagcaatgtt agggtcaaac ttagctcaag gggctgcttc gatggctgtt
     2401 gcattaaaga gtaaaaataa taatacaaaa caaattgctt ttgcagcagg tttctcagcc
     2461 ttacttgcag ggattaccga acctgcatta tatggtgtga ctttaaaata taaaaaaccg
     2521 ctttatgcag ctatgattgg tggtggatta gcgggattat ttgcaggtct tactagtgtt
     2581 aaagcatatc tatttgctgt cccatctttg atagcgttgc ctcaatttat ttattctgat
     2641 gtgccatcaa atattgtaaa tgctttaatt gtggcggtca tttcggttgt tattaccttt
     2701 gtattagctt atatatttgg aatcgatgaa gaagagagtt ctagcaattt agaagttaaa
     2761 gctggagttt caaataaaaa aatgatattt tctcctatat caggagaaat cattccgtta
     2821 agcgatgtcc aggataaaac attttcagat aaattaattg gagacggagt agcgattatc
     2881 ccaagtgaag gtaaggttta tgcaccattt gatgggaaaa ttacaaatat ttttccgact
     2941 aagcacgcaa ttggattgaa gagtgatgag ggtgttgagt tactaattca tattggatta
     3001 gatactgttg agctaaaagg tcaaggtttt attagtcatg tagaagaagg agacagagtt
     3061 ttcaaaaatc agttgatttt tgaaatgaac ttgaatttaa tcaagactaa aggctacgaa
     3121 acagttacac cagtaattgt aacgaatacc aatgattttc tagatgtatt agtattacct
     3181 aataatcaga caatcgagca ttctaaggaa ttactggtaa tattataatg gaggaaagtt
     3241 atgaccattt ttccagatga ttttctttgg ggtggagcgg ttgcagctaa tcaagtagag
     3301 ggagcatata atgaagatgg taagggctta tcagttcagg atgtgttacc caaaggtgga
     3361 ttaggagaag caacagaaaa tcctacagaa gataacttaa aattgatagg tattgatttt
     3421 tatcataaat ataaggaaga tatatccttg ttttctgaaa tgggctttaa tgtttttcgt
     3481 acttctattg catggagtag aatttttcca aaaggagatg aggaagaacc taacgaagct
     3541 ggtttgaaat attatgatga attatttgat gaactacatg ctcacgggat agaaccactt
     3601 gtaactcttt cacactatga gactccatta tatttagcaa gaaaatatca tggatggatt
     3661 gataggagaa tgattcattt ttatgaaaaa tttgctcgaa cagttttaga aaggtataaa
     3721 gataaagtta aatattggct tacatttaac gaagtaaact ctgttttgga attaccgttt
     3781 actagtggag gaatagatat acctaaggag aatctttcga aacaagaatt atatcaagct
     3841 atacatcatg aattagtcgc ctcgagtttg gttacaaaaa ttgctcgtga gattaattca
     3901 gagtttaagg tggggtgtat ggtattagct atgccagctt atccaatgac tccaaatcca
     3961 aaagatgtat gggcgactca tgagtatgag aatctaaatt atctattttc agatgtgcat
     4021 gttagaggtt attatccgaa ttatgcaaaa agatatttta aggaaaatga cattaacata
     4081 gagtttgcag ctgaagatgc agagttatta aaaaattata ctgtagattt tttatccttt
     4141 agctattaca tgagtgtgac tcaatctgct attccaacac agtataattc aggagaaggg
     4201 aatattattg gtggtttagt aaatccttat ttagagtctt cagagtgggg atggcaaatt
     4261 gatccaattg gactacgtat aattttaaat agatattatg accgttatca aatcccatta
     4321 tttatagtag aaaatggatt aggtgctaaa gatcaactaa taaaagatga acttaataac
     4381 ttaaccgtcc aagatgatta tagaattcag tatatgaaag aacatttatt gcaagttgct
     4441 gaagctctac aggatggtgt tgaaattatg ggctatacgt cttggggatg tattgactgt
     4501 gtttctatgt ccactgcaca actttctaaa aggtacggtc tcatttatgt tgatcgaaat
     4561 gatgatggaa atggcacatt caatcgatat aagaaaatgt cctttacttg gtataaagga
     4621 gtgattgaat caaatggaga atccttattc aaatagtttg tttattgatg attagatatt
     4681 atcacggtta aggcaacatc tcattaaata taaaataaag aggtttggaa gacatcaaat
     4741 tctaaacctc tttattttat agggggatta attaatttaa ttttgttaca gagagccgat
     4801 tataaatagt taacttagga tagattggtt atatatagta gactgaatct aaaatagtac
     4861 gaaacaattg ctaaaacatt tatagaaatt aattttactt tcccaatcga tttgttttca
     4921 tcttatttca atccgctata aagttagata agaataagct aacaagcaga agtaagatag
     4981 gtcttgcaag aatggtaaaa atctgataaa ctaagtagta attgaatagg aatctgaaag
     5041 actagtagcc caagggaagt atatcaggga ggagagccgt gactgcaagc tctctatatg
     5101 aaagctgggt gaattcactt gcgcatggat ttagaaatga aggtctgact tgtcagatga
     5161 aaacggatgg taccgcgtgt caacgctccg agtggagttt ttggcatgtg gttttctttt
     5221 tatctacgag agactgatgg aggaaatatg tcaactattg aagaacaatt aaaagcgctt
     5281 cgcgaagaaa cgctggctag cttgaagcag attactgctg gaaatgaaaa agagatgcaa
     5341 gatttgcgtg tctctgtcct tggtaaaaag ggttcgctca ctgaaatcct caaagggatg
     5401 aaagatgttt ctgctgagat gcgtccaatc atcgggaaac acgtcaatga agctcgtgat
     5461 gtcttgactg ctgcttttga agaaacagct aagctcttgg aagaaaagaa agtcgcggct
     5521 caactggcta gcgagagtat cgatgtgacg cttccaggtc gtccagttgc gactggtcac
     5581 cgtcacgttt tgacacaaac cagtgaagaa atcgaagata tcttcatcgg tatgggttat
     5641 caagtcgtgg atggttttga agtggagcaa gactactata actttgaacg tatgaacctt
     5701 ccaaaagacc acccagctcg tgatatgcag gatactttct atatcactga agaaatcttg
     5761 ctccgtaccc acacgtctcc agttcaggcg cgtgctatgg atgcccatga tttttctaaa
     5821 ggtcctttga agatgatctc gccagggcgt gtcttccgtc gcgatacgga cgatgcgacc
     5881 cacagtcacc aattccacca aatcgaaggc ttggtagttg ggaaaaatat ctctatggct
     5941 gatcttcaag gaacgcttca gttgattgtc caaaaaatgt ttggtgaaga gcgtcaaatt
     6001 cgtttgcgtc catcttactt cccattcaca gagccatctg ttgaggtgga tgtttcttgc
     6061 ttcaagtgtg gtggagaagg ctgtaatgta tgtaagaaaa caggttggat cgaaattatg
     6121 ggggccggta tggttcaccc acgtgtcctt gaaatgagtg gtatcgatgc gactgtatac
     6181 tctggctttg cctttggtct tggacaagag cgtgtagcta tgctccgtta tggaatcaac
     6241 gatatccgtg gattctacca aggagatgtc cgcttctcag aacagtttaa ataatgatta
     6301 gaaaagtaga aatggcagat gttgaggtgt tggctaaaat tgccaaacaa gcctttcgtg
     6361 aaacctttgc gtatgataat acggaagagc agttacagga atactttgaa gaggcttata
     6421 gtctgaaaac tttgtcaact gagttgggaa atcctgactc tgaaacctat ttcattatgc
     6481 atgaggagga gatagctggt tttctcaaag tcaactgggg aagtgctcaa actgagagag
     6541 aattagagga cgcttttgaa attcaacgcc tctatgtgct acaaaaattc caaggatttg
     6601 gactaggtaa gcaactgttt gaattcgcac ttgaacttgc tacaaaaaat agtttttctt
     6661 gggcttggct aggtgtttgg gagcataata caaaagctca agcgttttat aaccgatatg
     6721 gttttgaaaa atttagccaa catcatttta tggttggtca aaaagtagat acggattggt
     6781 tactgagaaa gaaattaagg taagaagaga attcttctat tgaaatgata ggaaaggaaa
     6841 agaaccagtg tggcaatggt cattctggag aactaaatta tgcttgtatc ttataaatgg
     6901 ttaaaagaat tggtgggcat tgatgtgcca tcacaggagt tggctgaaaa aatgtcaacc
     6961 acagggatcg aggtcgaagg tgtcgaatca ccagctgccg gtctttcaaa aattgtcgtc
     7021 ggtgagatct tgtcttgcga agatgtgcca gaaactcacc ttcatgtttg tcaggttaac
     7081 gttggcgaag aagaagagcg tcagatcgtt tgtggtgccc caaatgtgcg tgcaggcatc
     7141 aaggttatgg tggctcttcc gggagctcgt atcgctgaca attacaaaat caaaaaagga
     7201 aaaatccgtg gcttagagtc acttggaatg atctgttcac ttggtgaatt gggtatttct
     7261 gactcagttg tacctaagaa attcgcagat ggtattcaaa ttttgccaga aaatgccgtt
     7321 ccaggtgagg aagtcttttc atatctagac ttggatgatg aaatcatcga actttctatc
     7381 acaccaaacc gtgcagatgc cctttctatg cgtggagtgg ctcacgaagt ggcagccata
     7441 tatgacaagg cagtcaactt taaagaattt actttgacag aaacaaatga agctgcgaca
     7501 gatgcccttt ctgtgggcat tgagacagac aaggcgcctt actatgcagc tcgtatcttg
     7561 gacaatgtga ctatcgcacc aagtccacaa tggttgcaaa accttctcat gaacgaaggc
     7621 atccgtccca tcaataacgt tgtagacgtg acaaactaca tcctgctcta ctttggtcaa
     7681 cctatgcatg cttttgactt ggacacattt gaagggactg acatccgtgt gcgtgaagcg
     7741 cgtgctggtg aaaaattggt gaccttggac ggtgaagaac gtgacttgga cgtgaatgac
     7801 ctagtcatca ctgttgcaga caagccagta gcccttgcag gtgtcatggg tggtcaagca
     7861 acagaaatct ctgaaaaatc tagtcatgtt gtccttgaag ctgctgtttt caatggcaaa
     7921 tctatccgta agacaagtgg tcgcctgaac cttcgttctg agtcatcttc tcgctttgaa
     7981 aaaggaatta atgtggcaac agttaatgaa gcccttgatg cggcagctag cctgattgcg
     8041 gaacttgcag gtgcgacggt gcgtaagggt atcgtttcag cgggtgagct tgatacttca
     8101 gatgtagaag tttcttcaac tcttgctgat gttaaccgtg tcctcggaac tgagctgtct
     8161 tatgctgatg tcgaagacgt cttccgtcgt cttggctttg gtctttctgg aaatgcagac
     8221 agctttacag tcagcgtacc acgtcgtcgt tgggatatca caatcgaagc tgatctcttt
     8281 gaagaaatcg ctcgtatcta tggatatgac cgcttgccaa ccagccttcc aaaagacgat
     8341 ggtacagctg gtgaattgac tgtgacacaa aaactcagcc gtcaagttcg taccattgct
     8401 gaaggagcag gtttgacaga aatcatcacc tatgttctaa caactcctga aaaagcagtt
     8461 gagtttacgg ctcaaccaag taaccttacg gaactcatgt ggccaatgac tgtggatcgt
     8521 tcagtcctcc gtcaaaatat gatttcaggt atccttgata ccgttgccta caacgtggct
     8581 cgtaagaata aaaacttggc cctttacgag attggaaaag tctttgaaca aacaggtaat
     8641 ccaaaagaag aacttccaaa tgaaatcaac agttttgcct ttgccttgac aggcttggtt
     8701 gctgaaaaag atttccaaac agcagcagtt ccagttgatt tcttctatgc taaaggaatc
     8761 ctagaagcgc tctttactcg cttgggacta gaagtgacct atacagcaac agctgagatt
     8821 gccagccttc acccaggacg tacagcagtc atttcactcg gtgaccaagt tcttggtttt
     8881 cttggccaag tgcatccagt cactgctaag gcttacgata ttccagaaac gtatgtggct
     8941 gagctcaacc tttcagtcat cgaagctgcc cttcaacctg ctgctccatt tgtggaaatc
     9001 acgaaattcc cagcagtcag ccgtgacgtt gcccttctcc tcaaggcagc agtaactcac
     9061 caagaagtta tagatgctat ccaagctgcc ggcgtgaaac gtttgacaga tatcaaactc
     9121 tttgacgttt tctcaggtga gaaattggga cttggtatga agtcaatggc ttatagcttg
     9181 accttccaaa atccagaaga cagcttaacg gacgaagaag tcgcacgcta catggaaaaa
     9241 atccaagcat cgcttgaaaa aaaagtgaac gcagaagtgc gttaaacgat agtaggatac
     9301 aaattccccc tctagtttat gaacactaga ggggtgattt tatataatac tcaatgaaaa
     9361 tcaaaaagca aactaggaag ctagccgtaa gctgtacttg agtactgtaa ggcgaggctg
     9421 acgtggtttg aagagattgt cgaagagtat aaaataatta aaatgtgatt tctgtaaaaa
     9481 tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca tagtagtggt
     9541 ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt tggctattcc
     9601 aagttcctct ttcaaaaggt ggtagtacat ttaatgcgtc cctatgagag cttatttttg
     9661 caagtgctcc atgacgcata gttgcattaa aatcatctgc aataatagcc tttggatatt
     9721 ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc attaaacctg
     9781 gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt ctcgaatgta
     9841 atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag aaaccataac
     9901 ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga gaagtgaaaa
     9961 tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt ctctggtttt
    10021 cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg gcgtcaaaat
    10081 ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc caagttacta
    10141 attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt ccgaataata
    10201 gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt ttatttttct
    10261 tgtaaaaaga tagggaaaaa aatacgaaac ttaaaatagc agccatagtt gcagtagcta
    10321 aggggaaggc ataaatctgt gccaagatag gtctggtaga tagccaaata ttaagattag
    10381 aagatggaaa aaaagaataa gttatgatag ggataacaaa gagaatgacc gaaagggcag
    10441 agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct cggagctaat
    10501 gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat agattaagta
    10561 caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac agaaatgcaa
    10621 gacaattata ctacaaaagg caaacatttg acaatcgata gccgtcgctt aatcgaaaga
    10681 tggaaaaaag aagggaaatc aaatagagaa attgcctctc tgcttggaaa agttcctcaa
    10741 actatccaca ctgaaatcaa gcgtgggaca gtccgacaat gtcttggaaa agggcgcttc
    10801 aaagaggttt attctgccga ctatgctcaa cagtcttatg aaaacaatcg caagcgctcg
    10861 gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta tcataaccaa
    10921 aaattttcgc ttgaaatgat ggtgatggct aaaggggtta acgtgggaat ttcaaccatt
    10981 tactattgga ttcatcgtgg aaaattgggg ttaagcaagc aggatctgct ttaccctaga
    11041 aaaggaaaag cgcttaagaa acaggctagc accaacttta aacctgctgg tcaatctatc
    11101 gaatcataat tcgctcattc ttttaaaaat acatagacgt aaaagaaaga gggttaagtg
    11161 atgaagaata gtgctattgg gagtaattgg aaggatgtcc atctgagctc tttagcaagg
    11221 aggaaatcct tgaaagtgat atgcgagtgg ctatcatgag cgagttgatt gaggctaggt
    11281 atgaacaagg aatcagtcag aaaaagctgg aagaagtcag tggagtgagt caacctgtca
    11341 tagctaggat ggaaacagga gagagcagtc ttcagttgga tacggtctta aaagttctaa
    11401 ccagtctagg aaagacacta gcagtcgttc cacttgaaca ggggaaaagt tgactagaat
    11461 cagttatagt cttttctaat aacaggtcat agtcacttat aagaattact aataacatgt
    11521 tttagtattc taattggaat atagctgtaa agtaagaatt acaaaggatt tgagacgttt
    11581 gcttcaagtc tttttctttt gtccgaaaca gatatatagt ttcaaactat atcaaaccct
    11641 aattttttac aattatacag acgctttctt ttctgttaag atagtttcaa caacaaattt
    11701 tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg aattccgtga
    11761 attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag aacttttagc
    11821 agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag gcatcactga
    11881 aattccatca aatgactttt ctcactatga taacttccta gatgcggctt tccttttcaa
    11941 cgtggtgcct gcatccgttc aaaacttgga cttgtctgac cttgagcgct acttcgcttt
    12001 gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga agaaatggtt
    12061 caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag taaaattggc
    12121 tggtcacaag attttcgatg agttccaaga agccaaagaa cttggattga acactcgtcc
    12181 tgttcttgta ggtcccttca ctttccttca attgtcagac tttgaagaag gcgtgaaagc
    12241 agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta aattggctga
    12301 acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact tgacagctga
    12361 agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa aaggtcttga
    12421 agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc ttgtaaactt
    12481 accagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg aactcgttaa
    12541 aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta aaaacatctg
    12601 gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa attccagctg aaaacatcgt
    12661 tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg aagaatttga
    12721 accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa tccgtgactt
    12781 ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag aactctttgc
    12841 gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct tgacagacgc
    12901 agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag aagctttcaa
    12961 acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag aagttcgtgc
    13021 caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg ctttccttgc
    13081 tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg tccttgttca
    13141 cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt caggatacct
    13201 cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac caccaatcat
    13261 ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct atgcacaaag
    13321 tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc ttaactggtc
    13381 attcccacgt gaagacatct ctatcaagga ttctactctt caaatcgccc ttgctatcaa
    13441 ggatgaagtg cttgaccttg aagctgctgg tgtgaaaatc atccaaattg atgaggctgc
    13501 tcttcgtgaa aaattgccac tccgtcgtag tgactggtac gaagattacc ttgactgggc
    13561 aattcctgcc ttccgcttgg tacactcaac agtagcgtca gacacacaaa tccacactca
    13621 catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg atgcagacgt
    13681 tatttccttt gaagccagcc gttcaaacct tgaaatcttg gacgaactca aagcgaaaaa
    13741 cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg taccaaatga
    13801 aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca agaaagtttg
    13861 gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag aaagcttgat
    13921 ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga tttctctcca
    13981 tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt cacgccaaac
    14041 accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg gtaacattat
    14101 ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa ctgccagcaa
    14161 taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc aaaatgactt
    14221 ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca aggttgctga
    14281 aactattgct gacttggaca aagttggggt tcagaaaatc ttggctcttc gtggggatat
    14341 tattccagac gtagaaccac aaaaggattt ccgctatgca accgacttga ttgagtttat
    14401 caaggaacaa gcccctcact ttgatattat tggagcttgc tatccagaag ggcatccaga
    14461 ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg caggctgttc
    14521 gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc aggacaagtg
    14581 tatcttggct gggattgatg ttcctattca tgcaggaatt atgccaattc tgaatcgaaa
    14641 tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca aatttaaagc
    14701 catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac ttgcctatgc
    14761 agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc tctatacgat
    14821 gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt ttaatcacca
    14881 gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt tcctttttaa
    14941 tggtaaagac ctcacttttt aagaaaaata tgataaaata gattctgtac gtacttgata
    15001 caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa cgacacgagt
    15061 gagtcaaatc gatgttattt gacgaaagag ttagtaaagc atttagctaa tcgcccgata
    15121 gcgattagcg tgaaaggttt agatacttta atattaaacc tttctaatga tgtatcttga
    15181 aaactgaaca cgcctacaac tctgtggaaa aagataaatc tgcctaggag cagtcgctcc
    15241 gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt gatgacttga
    15301 attttggtct catttcttag gaaaaaagat aagcttccta gcactcgtcg agtgcgacgt
    15361 caccttccta tttttctaca gaaatgttcg gcaagccgaa ccgtccaaaa tatcttgtgt
    15421 aattgaacac ggccgaaaag ctgtgtaaaa aagataaact gtcttgtctt catcgaagac
    15481 ttcgtcagtt tcctattttt actttgcttt tgacgtcctt ggtatcttga tctttgtagg
    15541 caaggcgtat aatttcatca atccaaaggg gattaaaatg gcaaaacaag tgtttcaaac
    15601 gacttttgcg ggtcgtgagt taattgtaga gactggtcag gttgctaagc aagcaaatgg
    15661 ctctgttgtc gtacgttacg gtgagtcaac tgtcttgact gctgccgtta tgtctaagaa
    15721 aatggcaact ggggattttt tcccactcca agtcaactac gaagaaaaaa tgtatgcggc
    15781 tgggaagttt cctggtggct ttatgaaacg tgaaggacgt ccttcaacag atgcgacctt
    15841 gacagcgcgt ttgattgacc gtccgattcg tcctatgttt gcggaaggtt tccgtaatga
    15901 agtccaagtc atcaatacag tgctttctta tgatgaaaat gcatctgcac caatggctgc
    15961 tatgtttggt tcatctttgg cactgtctat ttcagatatt ccatttgacg gaccaattgc
    16021 tggggtacaa gtgggatatg tagatgacca aatcatcatc aacccaagtc aagaacaagc
    16081 agagcaatct cttcttgaat tgacagtagc tggaactaag cacgctatca acatggtaga
    16141 gtctggtgcc aaagaattgt cagaagaaat catgttggaa gcgcttctta aagggcacga
    16201 agctgtcaaa gaattgattg ccttccaaga agaaatcgtt gctgctgtcg gtaaagaaaa
    16261 agcagaagtg gaattgcttc acgtggatgc tgaattgcaa gctgaaatca ttgcagccta
    16321 caacagtgac ctccaaaagg cagttcaagt agaagagaaa ttggcccgtg aagctgcaac
    16381 tcaagcagtg aaagaccaag tgactgccgt ttacgaagaa aaatatgcgg accacgaaga
    16441 atttgaccgt attatgcgtg atgtggctga aatcttggaa caaatggaac acgcagaagt
    16501 gcgacgttta attacagaag acaaggtgcg tcctgatggt cgtaaggtcg atgaaatccg
    16561 tcctttggat gcggttgttg acttccttcc tcgtgtacat ggttcaggtc tctttactcg
    16621 tgggcaaact caagctcttt cagtcttgac cttggctccg atgggagaaa ctcaaatcat
    16681 tgatggtttg gatccagagt acaagaaacg ctttatgcac cactataact tccctcaata
    16741 ttctgtaggg gaaacaggtc gttacggtgc gccaggtcgt cgtgaaatcg gtcacggtgc
    16801 ccttggtgag cgtgctcttg ctcaagtctt gccaagcttg gaagaattcc catacgctat
    16861 ccgtctagta gcagaagttt tggaatcaaa cggttcttca tctcaagctt ctatctgtgc
    16921 gggaactctt gcccttatgg ctggtggtgt gccaatcaag gcgccagtag ctggtattgc
    16981 tatgggactt atctcagatg gaaataacta cacagtattg acagatatcc aaggtttgga
    17041 agatcacttt ggagatatgg acttcaaggt tgcaggtact cgtgatggga ttacagccct
    17101 tcaaatggat atcaagattc aagggattac tgcagaaatc ttgacggagg ctcttgctca
    17161 agccaagaaa gcgcgttttg aaatccttga tgtcattgaa gcaaccattc cagaagttcg
    17221 tctagaattg gctccaactg ctccgaaaat tgatacgatc aagattgatg tggacaagat
    17281 taagattgtc atcggtaagg gtggagaaac catcgacaag attatcgctg aaacaggtgt
    17341 taagattgat atagacgaag aaggaaatgt gtctatctac tctagtgacc aagatgctat
    17401 taaccgtgcc aaagaaatta ttgctggttt ggttcgtgaa gccaaagtgg atgaagttta
    17461 ccgtgctaaa gtcgttcgta tcgagaaatt tggtgccttt gttaacctct ttgataagac
    17521 agatgccctt gttcatatct ctgagatggc ttggactcgt accaatcgtg tagaggattt
    17581 ggtagaaatc ggggatgaag ttgatgttaa ggttatcaag attgatgaaa aaggccgtat
    17641 cgatgcctct atgaaggctc ttctacctcg tccgccaaaa cctgagcatg atgaaaaagg
    17701 tgaaaagtct gagcgtcctc accgcccacg tcatcacaag gatcacaaac ctaagaaaga
    17761 atttacagaa acaccaaaag attcagaata agaaaaggag aaatgtatgg ggtggtggcg
    17821 cgaaaccatt gatatcgtaa aagaaaatga tccagcggcc cgcaccactt tggaggtttt
    17881 gctgacttat ccaggtgtca aggccttggc ggcccaccgt ctctcgcatt ttatctggaa
    17941 gcacggcttc aaactcttag ctcgtatgca cagtcagttt tggcgctttt ggactcagat
    18001 tgagattcat ccaggagccc agattgattc aggtgtcttt attgaccatg gttctggtct
    18061 ggtgattgga gagacagcga ttgttgaaaa aggcgttctt ctctatcacg gagtgactct
    18121 tgggggaaca gggaaagact gtggcaaacg ccatccgact gtacgaaagg gagccctcat
    18181 atcagcccat gcccaagtta tcggacctgt ggaaattggt gaaaatgcca aggtcggtgc
    18241 tgcagcagtt gtcgtagcag atgtacctag tgatgtgacg gttgtcggta ttccggccaa
    18301 gattgtccgt cttcatggta agaaagatga gcctgtcatt cacgaagtcg aagaaaaacg
    18361 agagtattat gtcaataaac tcgagcaggc taaagatgcc agtcacagat cgtctggttt
    18421 gtagaggata cctatatgat tcaagtaaga aacaagttaa gccaagagga gctatctgag
    18481 gcgaaaaaag taattaactg ttgccaaaac tatgacggta cctatcgcga tccctatctc
    18541 tctaacatgc ttaattttga cccaaacatg cccgcctttt tcctttatta tgaaaaaggc
    18601 gaacttgttg gtttattaac tgtctatgca gatgaccaag atgtagaagt gacgatactg
    18661 gttcatccag gtcatcgccg tcaggggatt gcgcgtgcat tgtttactag ttttgagaga
    18721 gaaacagctt ctttccccat tcgatcagtc acttttcaga cagaacgtat ttttttagag
    18781 aatcatcctg actttgccag taactgggga ctaatcgagg atgaagagac agaaacttgg
    18841 ttaggtaagg atagaagacc ttatccgtta gcaaatgttt cccatattga agttttgtta
    18901 gcagatagtt cgtatcagga tcaaattagt caattaaaat ttcaggcatt ttcagaggaa
    18961 catgaatcga gagaagttgt ggatagatat gtcgctgaag ctctgaagga tccagaaagc
    19021 cgactatata ttttgttaaa agacggtcag gttattggga cttgcacggt agatttatcg
    19081 actaatacga attacttcta cggtttagca atatcggaac ctgaacgtgg gaaaggctat
    19141 ggaagctact tagcaaaatc cctcgtcaac caactaattg agcaaaatga caaggaattt
    19201 cagattgcag tggaagatag caatgtaggt gccaaacgtt tgtatgaaaa aattggcttt
    19261 gtcaaacaga ctcaggtggt ttatctgaat gagaaaggag caagggattc cgaagtgtag
    19321 agatattcgg actgaaattt acttgaactt ttagtgatga aactaattgt tcttggattt
    19381 cagctttctt gattatgatt tatgattaaa atctatgaca ccatgtctcg tgatttgcga
    19441 gaatttgtcc cgattgagga cggcaagatc aagatgtatg tttgtgggcc aacggtgtac
    19501 aactatattc atgtagggaa tgctcgttca acggtagctt ttgataccat tcgtcgctat
    19561 tttgagtatc gtgggtacga ggttgcctat atttccaatt ttacggatgt ggatgataag
    19621 attatcaacc gtgccaggga agaaggcatc acgcctcagg aggttgcgga taagtacatc
    19681 gctgcctttc gtgaggatgt gacggccttg ggcgtgaaac ctgcgactcg ccatccgcgt
    19741 gtagtggagt ttatggcaga catcatccgt tttgtggaag gcttgatcga gaaaggcttt
    19801 gcctatgaga gtcaagggga tgtctatttc cgtgtagaaa aatcccacaa ctatgctaaa
    19861 ttggctaata aaaccttgga agatttggag ctaggtgctt caggtcgtac cgatgaagaa
    19921 acggctcgta aggaaaatcc tgtagacttt gctctatgga aatcttccaa accaggtgag
    19981 atttcttggg atagtccttg gggacctgga cgtccgggtt ggcatattga gtgttcagtc
    20041 atgtcgacag agattttagg tgataccatt gatattcacg gtggtggagc tgacctagag
    20101 tttccacacc acaccaatga aattgcccaa tctgaagcta aaacaggcaa ggcttttgct
    20161 aactactgga tgcacaatgg ctttgtcaat atcgacaatg tcaaaatgtc taagtccttg
    20221 ggtaacttca ttacggtaca cgatgccctt aaaactcttg atgggcaagt acttcgtttc
    20281 ttctttgcga cccagcacta ccgtaagcct atcaacttca cggaaaaggc agttcgcgat
    20341 gccgagacca atctcaagta tctgaagaat acttacgaac aaccatttac aggaaacgtg
    20401 gatgcccaag agttacaaaa ctttaaagat aagtttgtag cagctatgga tgaagatttt
    20461 aatgctgcca acggtatcac agttgtcttt gaaatggcca aatggatcaa ctcagggaac
    20521 tatgatgcaa gtgtcaagca agctcttgca gatatgttag aaatttttgg aattgtcttt
    20581 gttgaggaag ttttggatgc agagattgaa gacttgattc aaaaacgcca agaggcgcgt
    20641 gccaatcgtg actttgcgac agcagaccaa atccgtgacc aattggttac tcaaggaatt
    20701 aagctccttg ataccaagga tggagtgagg tggacacgtg attgatgtca atctcattaa
    20761 cgggattgcg ctagcctttg agggagatgc ggtgtattct atgtatattc gccgccacct
    20821 catcctcaaa ggtatgacca agcccaataa actccaccaa gaggcgacca agtacgtgtc
    20881 agccaaggct caagctcgcc tgatttctct catgttggag gagcagatcc taacggaaaa
    20941 agaagaagaa atctacaaac gtggccgcaa taccaatagt cacacaaagg ctaaaaatgc
    21001 agatgtcgtg acttatcgta tgtccacggg atttgaagca gttatgggct atctccatat
    21061 gactgagaat ctggaacgtc ttgagagttt ggtttcatgg tgcatccaaa aagtggaggg
    21121 ctagaacatg agggcaaaag aactacaaga ctggtttcct gaggctcgga tttcagacca
    21181 accagtagag aaagagggct atctcacgct tcctttagct tctcagcagt ggattttgct
    21241 ggaggaagct gggctcagcg agcgtgaaaa gcagttggtt gcccttttga cccagcagga
    21301 gcaggctcgt tcgctaaacc cttggtattc ctatctggtt gaaggcaagg gacaggcacc
    21361 gcaagttttt aaaaagattc agttggttta ttgccatctt tcttattttc agcaggaaaa
    21421 tctggcttct tggctagata tgatgcggac tctttttccg aattgtcaga cagtgttaca
    21481 ggtcggagct caggattatg ttttcgtgct tcaacaagac aaatacactt ctgtaagaga
    21541 tattttaagt gatatgattg aagcagttga gtatgacttt ggacttcgtc tttctatcat
    21601 gttgggtcag gtttggtctc agacaggaca tcaagcccta tcagacttaa tcaaagctga
    21661 gcgggatttg ttcaagacat ggtggcgtca gggtcaccaa ggtgttcata ctttttctca
    21721 gctctatctt tggagtatgg gagaaagact cgtggacttg aagccaatta aagaatgtct
    21781 acaccagatg attttggatc aagatcagat tcaggaaatc attctctctc tttgggaaaa
    21841 tagtgctgtt ctcactaaaa cagcccagca actctatctg caccgcaatt ctctccaata
    21901 caagattgat aaatgggaag agttgacagg gcttcagttg aaagagttga ccgacctgac
    21961 cttgtgttat caattgattt taggttcttt gtcaactata gttggtttgt aaagaag
//
LOCUS       DAVAZV010000035        21460 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVAZV010000035 DAVAZV010000000
VERSION     DAVAZV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21460
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.035"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            66..287
                     /locus_tag="VQT46_001304"
     CDS             66..287
                     /locus_tag="VQT46_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371331.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTNSAYAKIERGEHTLTADV
                     LVTLSNFYDVSTDYLLELTDFPDKIRFRK"
     gene            804..1043
                     /locus_tag="VQT46_001305"
                     /pseudo
     CDS             804..1043
                     /locus_tag="VQT46_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            1187..2416
                     /locus_tag="VQT46_001306"
     CDS             1187..2416
                     /locus_tag="VQT46_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET2371332.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSAASVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            2436..5132
                     /gene="ppc"
                     /locus_tag="VQT46_001307"
     CDS             2436..5132
                     /gene="ppc"
                     /locus_tag="VQT46_001307"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET2371333.1"
                     /translation="MSLQKLENSSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    5215..5432
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5545..6549
                     /locus_tag="VQT46_001308"
     CDS             5545..6549
                     /locus_tag="VQT46_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2371334.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     IELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTIKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            6618..7484
                     /locus_tag="VQT46_001309"
     CDS             6618..7484
                     /locus_tag="VQT46_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371335.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            7481..8239
                     /locus_tag="VQT46_001310"
     CDS             7481..8239
                     /locus_tag="VQT46_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371336.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            8329..10089
                     /gene="dnaG"
                     /locus_tag="VQT46_001311"
     CDS             8329..10089
                     /gene="dnaG"
                     /locus_tag="VQT46_001311"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET2371337.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYRAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYTQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            10092..11201
                     /gene="rpoD"
                     /locus_tag="VQT46_001312"
     CDS             10092..11201
                     /gene="rpoD"
                     /locus_tag="VQT46_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET2371338.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            11215..11544
                     /locus_tag="VQT46_001313"
     CDS             11215..11544
                     /locus_tag="VQT46_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET2371339.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            11659..12702
                     /gene="cpoA"
                     /locus_tag="VQT46_001314"
     CDS             11659..12702
                     /gene="cpoA"
                     /locus_tag="VQT46_001314"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET2371340.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            12718..14043
                     /locus_tag="VQT46_001315"
     CDS             12718..14043
                     /locus_tag="VQT46_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2371341.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGILIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGALYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFRTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            14074..14250
                     /locus_tag="VQT46_001316"
     CDS             14074..14250
                     /locus_tag="VQT46_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET2371342.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            14309..14443
                     /locus_tag="VQT46_001317"
     CDS             14309..14443
                     /locus_tag="VQT46_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET2371343.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            14507..15817
                     /gene="obgE"
                     /locus_tag="VQT46_001318"
     CDS             14507..15817
                     /gene="obgE"
                     /locus_tag="VQT46_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET2371344.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            15827..15985
                     /locus_tag="VQT46_001319"
     CDS             15827..15985
                     /locus_tag="VQT46_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371345.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
     gene            17035..18294
                     /locus_tag="VQT46_001320"
     CDS             17035..18294
                     /locus_tag="VQT46_001320"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET2371346.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            18310..18861
                     /locus_tag="VQT46_001321"
     CDS             18310..18861
                     /locus_tag="VQT46_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371347.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLFIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            18854..20131
                     /locus_tag="VQT46_001322"
     CDS             18854..20131
                     /locus_tag="VQT46_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2371348.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIDRLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            20147..21007
                     /locus_tag="VQT46_001323"
     CDS             20147..21007
                     /locus_tag="VQT46_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET2371349.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            21230..21340
                     /locus_tag="VQT46_001324"
                     /pseudo
     CDS             21230..21340
                     /locus_tag="VQT46_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818216.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase"
BASE COUNT         6560 a         3687 c         4816 g         6397 t
ORIGIN      
        1 ccagttagga cactttgaat gatttcttag ttttatatat tatacttttc tcaggagaaa
       61 gctagatgta cagacgtttg agagatttga gggaagatca cgatttgacc caaaaacaaa
      121 tagctaaaat actttcgttt acaaactcag cttatgctaa aattgaacgg ggtgagcata
      181 cgttaacagc agatgtattg gtaactctct caaactttta cgatgtcagt acagactacc
      241 tattggaatt gacagatttt cctgataaaa ttcgctttag aaaataatct cctcaatttc
      301 atagagtgtg aaaatgagga gattttttat ttgttctttg aaaattaaat agtccaaaat
      361 ggtactttcc tcatttgtgg agcaaatttg aatggctcgc catgataaga gcgattttaa
      421 agccatcaat aaaatagagc gatactttat atgccatgat acaaatgata tacaatgata
      481 cttctgaccg ttcaggctgc catcgtaaaa gagcagcaag tgaaattctt atgatgactt
      541 catcagtcat gccacgttga atgtgtgagt ttgttagaga aacgcaatta atcctcaaaa
      601 ggttccccga accttttgag ttccacagac gcatcacgtg gagtgtgtaa gcttgttgct
      661 aaaagcgtaa aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa
      721 tacaataaaa ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagagc
      781 cttgtaggtg ttcagcgcac gagatgttag ctgtgttaaa aacagcttat caacgcaacg
      841 taaacgcgca aaaggtggac gaaaaaccaa attaagccta gacgatctcc tcatggtaac
      901 tattcaatac atgcgagaat agcgcactta tgaacaaatt gcggctgatt ttggcattca
      961 cgaaagcaac ataattagtc ggaggtcaat ggattgaagc aactcttatt caaaatggtt
     1021 ttacgatttc aaattctgcc ttaattctgt aaaaacagta aaattcgaag gattgtaagg
     1081 taagagtttt tttctttctg aaaaaatggt ataatagcaa tcaaaactag aaaataaaac
     1141 ggaatttgga acagatttgt ctgtatccta gtagagtggt gatactatga agattagtaa
     1201 gaggcactta ttaaattatt ccatcttgat tccctacttg cttttatcta ttttgggctt
     1261 gattgtggtc tattcgacca ccagtgctat tttaattgaa gaaggcaaga gcgccttgca
     1321 gttggttcga aaccaaggaa tcttttggat tgttagtttg atactgattg ccttaattta
     1381 taaattgaga ctagattttt tgagaaatga gcgactaatc attttagtta tattaataga
     1441 aatgctttta ttgttcttgg ctcgttttat tggtatttca gtaaacgggg catacggttg
     1501 gatttcggtt gcaggagtaa ctattcagcc agctgagtac ttaaaaatca ttattatttg
     1561 gtatttagct caccgattct ccaaacagca agaagaaata gctacttatg attttcaagt
     1621 tttgactcaa aatcaatggc ttccccgtgc ttttaatgat tggcgattcg ttctcctagt
     1681 tctgattgga agtttgggaa ttttccctga tttaggaaat gcgactattt tagtcttggt
     1741 ttccttgatt atgtatacag ttagtggaat cgcttatcgc tggttttcaa ccattctggc
     1801 gctcgtatct gccgcttctg tctttgtctt gaccactatc agcctaatcg gtgttgagac
     1861 cttttcaaaa attccagtat ttggctatgt agccaaacgc tttagtgcct tttttaatcc
     1921 ttttgccgat cgtgctgatg caggtcacca gttagctaat tcttattttg ccatggtcaa
     1981 tggtggttgg tttggtctag gtcttggaaa ctcgattgaa aaacgaggtt atttgccaga
     2041 agctcataca gactttgtct tttctatcgt gattgaagaa tttggctttg ttggtgccag
     2101 tcttatttta gctctcttgt ttttcatgat tttgcggatt atcttggtcg gtattcgagc
     2161 ggagaatcct ttcaatgcca tggttgcact cggtgtcgga gggatgatgt tggttcaggt
     2221 atttgtcaat atcggaggga tttcgggctt gattccatct acaggagtaa ccttcccctt
     2281 cttatcccag ggtggaaata gtcttctagt cttatcagtg gcagtagcct ttgtcttaaa
     2341 tattgatgcc agtgaaaaac gcgctaagtt gtaccgagaa ttggaaaatc aaccaatgaa
     2401 ccttctgttg aagtaggata aagaaaggat agtttatgtc tcttcaaaaa ttagaaaatt
     2461 ctagtaataa aagtgttgtg caagaagaag tcttgattct aacagaatta ctggaagata
     2521 ttactaaaaa tatgcttgcc ccagagacct ttgaaaaaat aatacagttg aaagaattat
     2581 caacgcagga agattatcaa ggtctaaacc gtctagtgac tagcttatca aatgatgaaa
     2641 tggtctatat ttcacgctat ttctctatct tgcctctttt gattaatatt tcagaggatg
     2701 tggatttagc ttatgaaatc aatcatcaaa ataatattga tcaggactat ttaggtaaat
     2761 tatctacaac gattaaattg gtagcagaaa aggaaaatgc cgttgagatc ctagaacact
     2821 tgaatgttgt tccggttttg acagcccatc caacacaagt gcaacgcaaa agtatgttgg
     2881 atttaacaaa tcatattcat agtcttttgc gtaaataccg tgatgttaag ttggggttga
     2941 tcaataaaga taaatggtac aatgatttgc gtcgttacat cgaaattatc atgcagacag
     3001 acatgattcg tgagaaaaaa ttaaaagtga ctaacgaaat cacgaatgct atggaatatt
     3061 ataacagctc ctttttgaaa gctgtacctc atttgacgac ggagtataag cgcttagcgc
     3121 aagcgcatgg tctgaattta aaacaggcta aaccaatcac catgggtatg tggataggtg
     3181 gtgaccgtga tggaaatcca tttgttacag caaagacctt gaagcagtct gcactcactc
     3241 aatgtgaagt catcatgaac tactatgata aaaagattta ccaactttat cgtgaatttt
     3301 ctctttcaac tagcattgtc aacgtcagca agcaagtcag agaaatggct cgtcaatcca
     3361 aggataactc gatttaccgc gaaaaagagc tttaccgtcg tgccttgttt gatattcaat
     3421 caaaaattca ggcaactaaa acctatctga ttgaggatga agaagttggg actcgttatg
     3481 aaaccgccaa tgatttctac aaggatttga ttgccattcg agattctcta ctagagaata
     3541 agggcgagtc cttgatttca ggtgattttg tggaattatt gcaggcagta gagatatttg
     3601 gtttttacct agcatcaatt gatatgcgac aagactctag cgtctatgaa gcctgtgtgg
     3661 cagaactctt gaaatcagca ggaattcatt ctcgttatag cgagttgagc gaagaagaaa
     3721 agtgtgacct tcttttgaaa gaattagaag aagatccccg aattctttct gcgactcacg
     3781 cagaaaaatc agaattatta gcaaaagaac tagctatttt taagacggct cgtgttttga
     3841 aagataagtt gggagatgat gtcatccgtc agaccatcat ttcacatgca accaaccttt
     3901 ctgatatgct agaattagct attctgttaa aagaagtagg actggtggat acggaaaggg
     3961 cgcgtgttca gattgttccc ctttttgaaa caattgaaga cttggatcat tcagaggaaa
     4021 caatgagaaa atatctttct cttagccttg ccaaaaaatg gattgactca cgaaataact
     4081 accaagaaat catgcttggc tactctgaca gtaataaaga tggcggttac ttgtcatcat
     4141 gttggaccct ctacaaggct caacaacaat tgactgctat tggagatgaa tttggcgtta
     4201 aggttacctt cttccatggt cgtggtggta ctgtcggtcg tggtggtggg ccaacctatg
     4261 aagccattac atctcaaccg ctcaagtcta tcaaggatcg tatccgtttg acggagcagg
     4321 gtgaagtaat tgggaataaa tacggtaaca aagacgccgc ttactataac cttgaaatgc
     4381 tagtatcggc agctattaac cgtatgatta ctcagaagaa gagcgatacc aataccccaa
     4441 atcgttatga agccattatg gatcaagtag tggaccgtag ttacgatatc taccgtgatt
     4501 tggtctttgg taatgagcat ttctatgatt atttcttcga gtcaagtcca atcaaggcta
     4561 tttcaagttt taatattggt tctcgtccag ccgctcgtaa gactattact gaaatcggtg
     4621 gtttgcgtgc catcccttgg gtattctcat ggtcacagag tcgtgttatg ttccctggat
     4681 ggtacggggt tggttcaagc ttcaaggaat ttatcaataa aaatccagag aatattgcta
     4741 tcttacgaga tatgtaccaa aattggcctt tcttccaatc gcttctttca aatgttgata
     4801 tggttttgtc aaaatcaaat atgaatattg cttttgaata tgctaaactt tgtgaagacg
     4861 agcaagttaa ggccatctat gagattattt taaatgaatg gcaagttact aagaacgtta
     4921 tcttggctat tgaaggacat gacgaactct tagctgacaa tccatatcta aaagctagtc
     4981 tggattaccg tatgccttac tttaatattc tcaactatat tcagttagag ttgattaaac
     5041 gccaacgtcg tggagaattg tccagtgatc aagaacgatt gattcatatc accatcaacg
     5101 gaattgcgac aggattgcgt aattcaggtt gataattttc aagagtgaat gctaaaagtg
     5161 aatatcaaaa aaattctaat agactattga caagtagttt aaaaatgata taatttaacc
     5221 attcagaaaa gtaatcatac aaacttttta gagagtctgt ggtagctgaa aacagataag
     5281 tggcgatgat gaaaattggg ctgaatgcta tttagaattt gaaattataa aaattcggta
     5341 agcacacctt acagtgcatc tcgttattgc gagactgagc gatagggaaa ttccctataa
     5401 ttgaggtggt accgcgcatc gacgtcctca cacaagtttt ttgtgtgagg atttttttga
     5461 tggaggttag tatggaaaga aaacgatggc gtcgcttgtt tagataagtg aaatatgtta
     5521 aaggaaataa aaaggagaaa cagaatgaaa aataaacgtt taattggaat tattgctgca
     5581 ttagcagtct tagtagcagg aagcttgatt tattcttcaa tgaataaatc agaagctcag
     5641 aataataagg atgagaagaa aataaccaag attggtgtgc ttcaatttgt gagccatcca
     5701 tcccttgatt tgatttataa agggatccaa gatggacttg cagaagaagg atataaagat
     5761 gatcaagtta aaattgattt tatgaactca gaaggtgatc aaagtaaggt tgcgacaatg
     5821 agtaaacaat tggttgcaaa tgggaatgac cttgtggttg gtattgcaac accagcagcc
     5881 caagggttgg ctagtgcaac aaaagaccta ccagttatca tggccgctat tacagaccca
     5941 attggtgcta acttggttaa agatttgaaa aaaccaggtg gtaacgttac aggggtatct
     6001 gaccacaatc cagctcaaca acaaattgaa ctcatcaagg ctctgacacc gaatgtgaaa
     6061 acaatcggag ctctttactc aagtagcgaa gacaattcaa aaacacaggt tgaagaattt
     6121 aaggcttatg ctgaaaaagc aggtctgaca gtggaaacat ttgcagttcc ttcaacaaat
     6181 gaaattgcct caactgtcac tgttatgact atcaaggtag atgctatttg ggttccaatt
     6241 gataacacca ttgcatcagg atttccaacg gttgtctcta gcaatcaaag ttctaagaaa
     6301 ccaatttatc ccagtgcgac agctatggta gaagtaggtg gtttggcatc agttgtaatt
     6361 gaccaacatg accttggtgt ggcaacaggt aaaatgattg tgcaagtctt gaaaggtgca
     6421 aaaccagccg ataccccagt caatgtcttt tcaactggta agtcagtcat caataaaaaa
     6481 atagcacaag aactaggtat tactattcct gagtctgttc tcaaagaagc aggacaagtc
     6541 atcgaataaa taaggtaggg aggaggagac tcttcccatt ttttaaaaag atgaatatag
     6601 aaaggattaa ataaaatatg attgtttcca ttatttctca aggatttgtc tgggctattc
     6661 taggtctggg aatctttatg acatttagga ttttaaactt tccagatatg acgacagaag
     6721 gttccttccc tcttggggga gctgttgctg tcactttgat aaccaaaggc gtgaacccat
     6781 ttttagcgac acttgttgct gtaggagcag gttgtttggc tggaatggca gcaggccttc
     6841 tttatacaaa agggaagatc ccaaccttgc tctcagggat tttggtgatg acttcttgtc
     6901 actcaatcat gctcttgatt atgggacgtg cgaatttagg cctgcttgga accaagcaaa
     6961 ttcaggatgt tttgcctttt gattcggatt tgaatcaact cttgacaggt ctcatctttg
     7021 tgagcattgt tattgctctc atgctctttt tcttggacac taaactcgga caagcctata
     7081 ttgctacagg ggataatcct gatatggcta gaagtttcgg gattcatact ggacgcatgg
     7141 agctcatggg cttggtctta tcaaatggtg tgattgccct tgcaggtgcc ctcattgctc
     7201 agcaagaagg ctatgccgat gtgtctcgag ggatcggggt tatcgttgtg gggcttgcaa
     7261 gtttgattat tggagaagtt attttcaaga gtttgagctt ggcagagcgt ttggttacta
     7321 tcgttgtagg ttctatcgct tatcaatttt tagtgtgggc agttatcgca cttggcttta
     7381 atacaagtta ccttcgttta tacagtgcct tgattttagc agtctgcctc atgattccaa
     7441 catttaagca aacaatcttg aaaggagcca agttaagcaa atgacagcaa ttgtagaatt
     7501 aaaaaatgca accaaaattg ttaaaaatgg ctttgatgaa gaaaagatta ttttaaatga
     7561 tgtttcctta gaaatttttg aacgggactt tatcacgatt ttgggcggaa atggtgctgg
     7621 aaaatcaacc ctctttaaca ctatagcagg gaccttatca ctaactagtg gaactatccg
     7681 tattttaggt gaagatctca ctaagttttc acccgagaag cgtgccaagt acctgtctcg
     7741 tgtcttccaa gatccaaaga tggggacagc tccccgtatg acggtcgctg aaaatctttt
     7801 aatcgccaag tttcgtggtg agaagcgtgg attgttacca cgacgcttga ctagctataa
     7861 ggatgaattt caggcaacca ttgaaaaagt aggaaatggt cttgagaaac acttgaatac
     7921 accgattgag ttcttatcag gtggacaaag acaggctttg agtctcttga tggcaacctt
     7981 gaagcgacct gaattactcc tgttagatga gcatactgct gccctggatc caaagactag
     8041 tgttgctttg atggaattga cagatgaatt tgttaagaaa gatcagctaa cagcccttat
     8101 gattactcat catatggaag atgctctcaa atacggcaat cgcttgattg tcatgaaaga
     8161 aggacggatt atccaagatt taaaccaaga agaaaaagca aaaatgaaaa tctctgatta
     8221 ttatcaactc tttgaataaa gtagggaaaa tgagtgaaat ggtttacttt ttttctgaaa
     8281 taaagtatac tatataaagt aaactatgat aacatggagg tattgtgtat ggttgacaaa
     8341 caagtcattg aagaaatcaa aaacaatgcc aacattgtgg aagtcatagg agatgtgatt
     8401 tctttacaaa aggcaggacg gaactatcta gggctctgtc cttttcatgg tgaaaaaaca
     8461 ccttctttca acgttgtaga ggacaagcag ttttaccact gttttggttg tggtcgctca
     8521 ggtgatgtct ttaaattcat cgaggagtac caaggggtta cctttatgga ggctgtccaa
     8581 atcttaggtc agcgtgtcgg gattgaggtt gaaaaaccgc tttatagtga acagaagcca
     8641 gcctcgcctc accaagctct ttatgatatg cacgaagatg cggctaaatt ttaccatgct
     8701 attctcatga caacgactat gggcgaagag gccagaaatt acctttatca gcggggtttg
     8761 acagatgaag tgcttaaaca tttttggatt ggtttagcac ctccagaacg aaactatctc
     8821 tatcaacgtt tgtctgatca gtatcgtgaa gaggatttac tggattcagg cctgttttat
     8881 ctctcggatg ccaatcaatt tgtagacacc tttcacaatc gcattatgtt tcccctgaca
     8941 aatgaccaag gaaaggtcat tgccttctca ggtcgtatct ggcaaaaaac ggattcacaa
     9001 acttctaagt ataaaaacag ccgatcgact gcaattttta acaaaagtta cgaattatat
     9061 catatggata gggcaaaaaa atcttctgga aaaactagtg agatttacct gatggaagga
     9121 ttcatggatg ttattgcagc ctatcgggct ggaatcgaaa atgctgtggc gtcgatggga
     9181 acggccttga gtcgagagca tgttgagcat ctgaaaaggt taaccaagaa attggttctt
     9241 gtttacgatg gagataaggc tgggcaagcc gcgatattga aagcattgga tgaaattggt
     9301 gatatgcctg tgcaaatcgt tagcatgcct gataacttgg atcctgatga gtatctacaa
     9361 aaaaatggtc cagaagactt ggcctatcta ttaacaaaaa ctcgtattag tccgattgag
     9421 ttctacattc atcagtacaa acctgaaaac agtgaaaatc tgcaggctca gattgagttt
     9481 attgaaaaaa tagctccctt gattgttcaa gaaaagtcca tcgctgctca aaacagctat
     9541 attcatattt tagctgacag tctggcgtcc tttgattata cccagattga gcagattgtt
     9601 aatgagagtc gtcaggtgca aaggcagaat cgcatggaaa gaatttccag accgacgcca
     9661 atcaccatgc ctgtcaccaa gcagttatcg gctattatga gggcagaagc ccatctactc
     9721 tatcggatga tggaatcccc tcttgttttg aacgattacc gtttgcgaga agactttgca
     9781 tttgctacac ctgaatttca ggtcttatat gacttgcttg gccagtatgg aaatcttcct
     9841 ccagaagttt tagcagagca gacagaggaa gttgaaagag cttggtacca agttttagct
     9901 caggatttgc ctgctgagat atcgccgcag gaacttagtg aagtagagat gactcgaaac
     9961 aaggctctct tgaatcagga caatatgaga atcaaaaaga aggtgcagga agctagccat
    10021 gtaggagata cagatacagc cctagaagaa ttggaacgtt taatttccca aaagagaaga
    10081 atggagtaat aatggcaaca aaacaaaaag aagtaacaac atttgacgta caggtagcag
    10141 aatttatccg taatcataag caaaaaggga cagcaacaga tgatgaaatc aatgcaagtc
    10201 tggttattcc ttttaccttg gacgctgatg ggattgaaga tctcttgcaa cggattcagg
    10261 atgcagggat ttctatcaca gataacgaag gaaatccaag tgcgcgtgtt cttagcaatg
    10321 aagaagaacc agaactcagc gatgaggact tgattggatc aacttctgct aaggtcaatg
    10381 accctgtccg tatgtacttg aaagaaatag gggtcgttcc tctcttgacc aatgaagagg
    10441 agaaagagtt ggcactggct gttgaagctg gcgatatcga agccaaacaa cgtcttgcgg
    10501 aagccaatct tcgtttggtt gtttccattg ccaaacgcta tgtcggtcgt ggcatgcagt
    10561 tccttgactt gattcaagaa ggaaatatgg gcttgatgaa ggcggttgac aagtttgact
    10621 attctaaagg gttcaagttt tcaacttatg caacttggtg gattcgtcag gctatcactc
    10681 gtgctattgc ggaccaagct cgtaccatcc gtatcccagt tcacatggtt gaaactatca
    10741 ataaattggt tcgtgaacag cggaatctcc ttcaagaatt ggggcaagat ccgacaccag
    10801 aacagattgc tgaacgaatg gatatgacac ctgataaggt tcgtgaaatc ttgaagattg
    10861 cccaagaacc agtatctctt gaaactccta tcggtgaaga ggacgatagc caccttggag
    10921 actttatcga agatgaagtg attgaaaatc cagtggatta tacgactcgt atcgtcttgc
    10981 gtgagcaatt ggatgaaatc ttagatactc ttacagaccg tgaagaaaat gttctgcgtc
    11041 tacgttttgg actagatgat ggaaaaatgc gcacacttga agatgtgggg aaagtcttta
    11101 acgtaactcg tgagcgtatc cgtcagattg aagcaaaggc tttgagaaaa ctacgccaac
    11161 caagtcgcag caaaccgctt cgtgatttta ttgaagacta agagtgagga aaatatggct
    11221 tatacagaag agcaaattga aaacatcaaa acacggattt taacagcctt ggaagaagtc
    11281 atcgaccctg agttgggaat cgatattgtc aatcttggtt tgatctatga gattcgtttt
    11341 gacggtgaca cagggcaaac agagattgac atgactttga caactatggg ttgtccctta
    11401 gcagaccttt tgacagacca gatttatgat gctatgatag aggttccaga agtaacggat
    11461 actgaggtta aattagtctg gtatccagcc tggacagttg aaaaaatgag tcgctatgcc
    11521 cgcattgccc taggcattaa gtaaacatat aaaagcatgt gagagactag aggaaaagcg
    11581 aggaaatttc ccctcttttc ctctagtctc tcctttcttt tgctgatttt attcaaagaa
    11641 aatgatataa tagtagttat ggagaaaaag aaattacgca tcaatatgtt gagttcaagt
    11701 gagaaagtag caggacaggg agtttcaggt gcttaccgtg aattagttcg tcttcttcac
    11761 cgtgctgcca aggaccaatt gattgttaca gaaaatcttc caatcgaggc agatgtgact
    11821 cactttcata cgattgattt tccctattat ttatcaacct tccaaaagaa acgctcaggg
    11881 agaaagattg gctatgtgca tttcttgcca gctacacttg aaggaagttt gaaaattcca
    11941 tttttcttaa agggaattgt gaaacgctat gtattttctt tttacaaccg gatggagcac
    12001 ttggttgtgg tcaatcctat gtttattgag gatttggtag cagctggtat tccacgtgaa
    12061 aaagtgacct atattcctaa ctttgtcaac aaggaaaaat ggcatcctct accacaagaa
    12121 gaggtagtca gactgcgcac agatcttggt cttagtgaca atcagtttat cgtagtaggt
    12181 gctgggcaag ttcagaaacg taaagggatt gatgacttta tccgtctggc tgaggaattg
    12241 cctcagatta cctttatctg ggctggtggc ttctcttttg gtggtatgac agatggttat
    12301 gaacactata agaaaattat ggaaaatccc cctaaaaatt tgatttttcc aggcattgta
    12361 tcgccagagc ggatgcgcga attgtatgct ctagcggatc ttttcttgtt gcctagttac
    12421 aatgagctct ttcctatgac tattttagaa gctgcgagtt gtgaggctcc tattatgttg
    12481 cgtgatttag atctctataa ggtgattttg gagggaaatt atcgggcgac agcgggtaga
    12541 gaagagatga aagaggctat tttggaatat caagcaaatc ctgctgtctt aaaagatctc
    12601 aaagaaaagg ctaagaatat ttccagagag tattctgaag agcatctgtt acaaatctgg
    12661 ttggactttt atgagaaaca agccgcttta gggagaaagt aaaaagtgag gtaatctatg
    12721 cgaattggtt tatttacaga tacctatttt cctcaggttt ctggtgttgc gaccagtatt
    12781 cgaaccttga aaacagaact tgaaaagcag ggacatgctg tttttatctt tacgacgaca
    12841 gataaggatg tcaatcgcta cgaagattgg caaattatcc gcattccaag tgttcctttc
    12901 tttgctttta aggatcgtcg ctttgcctac cgaggtttta gcaaggcact tgaaattgct
    12961 aaacagtatc agctagatat tatccatact cagacagaat tttctcttgg cctgttgggg
    13021 atttggattg cgcgtgaatt gaaaattcca gtcatccata cctatcacac ccagtatgaa
    13081 gactatgtcc attatattgc taaggggata ttgatccggc cgagtatggt caagtatctg
    13141 gttagaggtt tcctgcatga tgtggatggg gttatttgcc ctagtgagat tgtccgtgac
    13201 ttgctatctg attataaggt caaggttgaa aaacgggtca ttcctactgg gattgaatta
    13261 gccaagtttg agcgtccgga aatcaagcag gaaaatttga aagaactgcg tagtaaacta
    13321 gggattcaag atggtgaaaa gacgttgctt agtctttcga gaatctccta tgaaaaaaat
    13381 attcaagcag ttttagcagc ctttgctgat gttctgaaag aggaagacaa ggttaaactg
    13441 gtagtagctg gggatggccc ttatctgaat gacctcaaag agcaagccca gaacctagag
    13501 attcaagact cagtcatctt tacagggatg attgctccta gtgagacggc tctttactat
    13561 aaagcggcgg atttcttcat ttcggcatcg acaagcgaaa cgcaaggttt gacctacttg
    13621 gaaagcttag ccagtggaac acctgtcatt gctcacggaa atccttattt gaacaacctc
    13681 atcagtgata aaatgtttgg agccttgtac tatggagaac atgatttggc tggtgctatt
    13741 ttggaagccc tgattgcaac accagacatg aatgagcata ccttatcaga gaaattgtat
    13801 gagatttcag ctgagaactt tgggaaacga gtgcatgagt tttatctgga tgccattatt
    13861 tcaaataact tccagaaaga tttggctaaa gatgatacgg tcagtcagcg tatctttagg
    13921 acagttttgt atcttccgca acaggtggtt gctgtacctg taaaaggatc tagacgcatg
    13981 ttgaaggctt caaaaacaca gttgatcagt atgagagact attggaaaga ccatgaagaa
    14041 tagaaagagg aacagctatg aaaaaaacaa ttaatgagaa gcggtcgtga taaaaagatt
    14101 gcgggtgttt gtgctggggt ggcccattat ctggatatgg atccgactat cgttcaagtc
    14161 atttggggtg ttcttacttg ctgttacgga gctggaattg tagcttacat tattttatgg
    14221 attatcgcac cagtagcaac tgactattga aaactagctc aattcatgct aagataatag
    14281 aaaatagaat gtaacgaagg agagaaaaat ggcatttgga gataatggaa atcgtaaaaa
    14341 aactatgttt gagaaaataa ccttgtttat cgtgattatc atgctagtag caagtttatt
    14401 gggaattttt gcaactgcaa ttggtgccct cagtaatcta taaaatagat tcaagaaaat
    14461 ttagtgactg ggatttccca gccctttttt aaagtgagaa gaaataatga gtatgttttt
    14521 agatacagct aagattaagg tcaaggctgg taatggtggc gatggtatgg ttgcctttcg
    14581 tcgtgaaaaa tatgtcccta atggaggccc ttggggtggt gatggtggtc gtggaggcaa
    14641 tgtggtcttc gttgtagacg aaggactacg taccttgatg gatttccgct acaatcgtca
    14701 tttcaaggct gattctggtg aaaaagggat gaccaaaggg atgcatggtc gtggtgctga
    14761 ggaccttaga gttcgagtac cacaaggtac gactgttcgt gatgcggaga ctggcaaggt
    14821 tttaacagat ttgattgaac atgggcaaga atttatcgtt gcccacggtg gtcgtggtgg
    14881 acgtggaaat attcgtttcg cgacaccaaa aaatcctgca ccggaaatct ctgaaaatgg
    14941 agaaccaggt caggaacgtg agttacaatt ggaactaaaa atcttggcag atgtcggttt
    15001 agtaggattc ccatctgtag ggaagtcaac acttttaagt gttattacct cagctaagcc
    15061 taaaattggt gcctaccact ttaccactat tgtaccaaat ttaggtatgg ttcgcaccca
    15121 atcaggtgaa tcctttgcag tagccgactt gccaggtttg attgaagggg ctagtcaagg
    15181 tgttggtttg ggaactcagt ttctccgtca catcgagcgt acacgtgtta tccttcacat
    15241 cattgatatg tcagctagcg aaggccgtga tccatatgag gattacctag ctatcaataa
    15301 agagctggag tcttacaatc ttcgcctcat ggagcgtcca cagattattg tagctaataa
    15361 gatggacatg cctgagagtc aggaaaatct tgaagaattt aagaaaaaat tgtctgaaaa
    15421 ttatgatgaa tttgaagagt taccagctat cttcccaatt tctggattga ccaagcaagg
    15481 tctggcaaca cttttagatg ctacagctga attgttagac aagacaccag aatttttgct
    15541 ctacgacgag tccgatatgg aagaagaagc ttactatgga tttgacgaag aagaaaaagc
    15601 ctttgaaatt agtcgtgatg acgatgcgac atgggtactt tctggtgaaa aactcatgaa
    15661 actctttaat atgaccaact ttgatcgtga tgaatctgtc atgaaatttg cccgtcagct
    15721 tcgtggtatg ggggttgatg aagcccttcg tgcgcgtgga gctaaagatg gggatttggt
    15781 ccgcattggt aaatttgagt ttgaatttgt agactaggag actggtatgg gagataaacc
    15841 gatatctttc cgagatgcgg atggtaattt tgtttccgcc gcagacgttt ggaatgaaaa
    15901 gaaattggaa gaactattta atcgtctcaa tccaaatcgt gccttgagat tggcacgaac
    15961 taaaaaggaa aatccatctc agtaaagaag ctaaaaaatc ccgtgcctca tcagacacgg
    16021 gattttgtgg tacgacaggc atgtatagca aactgaatct ggaatagcac agcatatctt
    16081 ctaaaatatt gttataaatt gatttgaatt tcaaaattaa attgtttgat tcttatctca
    16141 atttgttata gtatatctga tgtcaaagtt ctcggcgagt caaatagcga ttcccaagcc
    16201 tgactatcgt gaggtagcgg attaaaatgg tctggggata gaccgtttta agtctgacgc
    16261 tggaaataag aattgtcaga agaagggata gcgaaatcgt ggctctacga acaggaacgt
    16321 gataataagg cgtatatagc ggataagagg gcctcaaact ctaaagtcca aaaaggtagt
    16381 cgtaacctat atgcgtaaat cacgagagta attgaattcg tactaagatt ttctattttc
    16441 actgtaacct tttaacgtcc ttatatcttg tatacacgag gaaagatgta cgacttatcc
    16501 cgtgaggtct atcactataa agagaaaacg acagatagaa gtgatcctga gtcacggtta
    16561 tctttaaaat agattgtctg ataggacggt atgtataaaa cgcttctgtg aactgagaga
    16621 agggggagaa gttcttgcta aaatttagtt gaacagccgt attccgatac ttagataaga
    16681 gatctagtct tagctcctac tcagttttag gggataaaaa aggggaaata gcgattcgag
    16741 aaagattata ctcttcgaaa atctcttcaa atcacgtcaa tatcgccttg ccgtatgtgt
    16801 aggatactga ctacgtcagt tccatctaca acctcaaaac agtgttttga gcaacctgcg
    16861 gctagtttcc tagtttgatc tttgattttc attgagtatt agtaattcag ttactaactc
    16921 gtcaactctg atttatccaa taaaattgaa aaggatggaa aaaaggataa atttatgata
    16981 tactttattt tgaagacctt attagaaatc ttgaaagagt attgaaaact tagaatgaga
    17041 aaaattgtta tcaatggtgg attaccactg caaggtgaaa tcactattag tggtgctaaa
    17101 aatagtgtcg ttgccttaat tccagctatt atcttggctg atgatgtggt gactttggat
    17161 tgcgttccag atatttcgga tgtagccagt cttgtcgaaa tcatggaatt gatgggagct
    17221 actgttaagc gttatgacga tgtattggag attgacccaa gaggtgttca aaatattcca
    17281 atgccttatg gtaaaattaa cagtcttcgt gcatcttact atttttatgg gagcctctta
    17341 ggccgttttg gtgaagcgac agttggtcta ccgggaggat gtgatcttgg tcctcgtccg
    17401 attgacttac accttaaggc gtttgaagct atgggtgcca ctgctagcta cgagggagat
    17461 aacatgaagt tatctgctaa agatacagga cttcatggtg caagtattta catggatacg
    17521 gttagtgtgg gagcaacgat taatacgatg attgctgcgg ttaaagcaaa tggtcgtact
    17581 attattgaaa atgcagcccg tgaacctgag attattgatg tagctactct cttgaataat
    17641 atgggtgccc atatccgtgg ggcaggaact aatatcatca ttattgatgg tgttgaaaga
    17701 ttacatggga cacgtcatca ggtgattcca gaccgtattg aagctggaac atatatatct
    17761 ttagctgctg cagttggtaa aggaattcgt ataaataatg ttctttacga acacctggaa
    17821 gggtttattg ctaagttgga agaaatggga gtgagaatga ctgtatctga ggacagcatt
    17881 tttgtcgagg aacagtctaa tttgaaagca atcaatatta agacagctcc ttacccaggc
    17941 tttgcaactg atttgcaaca accgcttacc cctcttttac taagagcgaa tggtcgtggt
    18001 acaattgtcg atacgattta cgaaaaacgt gtaaatcatg tttttgaact agcaaagatg
    18061 gatgcggata tttcgacaac aaatggtcat attttgtaca cgggtggacg tgatttacgt
    18121 ggggccagtg ttaaagcgac cgacttaaga gctggggctg cactagtcat tgctgggctt
    18181 atggctgaag gtaaaactga aattaccaat atcgagttta tcttacgtgg ttattctgat
    18241 attatcgaaa aattacgtaa tttaggagcg gatattagac ttgttgagga ttaaaccgta
    18301 gaggtgttta tgaatatttg gaccaaatta gcaatgtttt ctttttttga aacggatcgc
    18361 ttgtatttgc gtcctttctt ttttagtgat agtcaggact tccgcgagat agcttcaaat
    18421 ccagaaaatc ttcaatttat tttcccaacg caggcaagtc tggaagaaag tcaatatgca
    18481 ctggccaatt actttatgaa gtcccctttg ggagtgtggg caatttgtga ccagaaaaat
    18541 caacaaatga ttggttctat taaatttgag aagttagatg aaatcaaaaa agaagctgag
    18601 cttggctatt ttttgagaaa agatgcttgg tcgcaaggat ttatgacaga ggttgttaga
    18661 aaaatttgtc agctttcttt tgaggaattt ggcttaaaac aattatttat cattacccac
    18721 cttgaaaatg aagctagcca aagagttgct cttaagtctg gatttagttt gttccgtcag
    18781 tttaagggaa gtgatcgtta cacaagaaaa atgcgggatt atcttgaatt tcggtatgta
    18841 aaaggagagt tcaatgagta agcatcagga aattctaagc tatttggagg aattaccagt
    18901 aggtaaaagg gtcagtgttc gtagcatttc gaatcatcta ggagttagtg atggaacagc
    18961 ctatcgagct attaaagaag ctgaaaaccg tggaattgtg gagacccgtc ctagaagtgg
    19021 aacaattcgt gttaaatccc agaaagttgc tatagataga ttaacgtttg ctgaaattgc
    19081 agaagtgact tcttctgagg ttctggctgg gcaagaaggt ttagagagag aatttagtaa
    19141 gttttcaatt ggtgccatga ctgaacaaaa tatcttgtct taccttcatg atggggggct
    19201 cttgattgtc ggagaccgaa cccgtattca gttgctagcc ttggaaaatg aaaatgcagt
    19261 tctggttaca gggggatttc aggttcatga tgatgtgctt aaactggcca atcaaaaagg
    19321 gattcctgtt ctaagaagta agcatgatac ctttaccgtc gctaccatga tcaataaagc
    19381 cttgtcaaat gtccaaatca agactgatat tctgacagtt gagaaacttt atcgccctag
    19441 tcatgagtat ggttttctga gagagacaga tacagttaaa gattatttgg acttggttcg
    19501 taagaatcgt agcagccgtt tccctgttat caatcaacat caggtcgttg ttggcgttgt
    19561 aaccatgaga gacgctggtg ataaatcacc aagcacgaca attgataagg ttatgtctcg
    19621 tagtctattt ttggttggat tatcgacaaa tattgccaat gtgagtcaac ggatgatcgc
    19681 agaagacttt gaaatggtac cagttgttcg aagcaatcaa actttgcttg gcgttgtgac
    19741 gcgacgagat gtcatggaga agatgagccg ttcccaagtt tcggctctac caactttttc
    19801 tgagcagatt ggacaaaagc tctcttatca ccatgatgaa gtagtcatta cagtggaacc
    19861 ctttatgcta gaaaaaaatg gagttttggc taatggtgta ttggcagaaa ttctgaccca
    19921 catgacccaa gatttagttg ttaatagtgg tcgcaatctc attatcgagc agatgctgat
    19981 ctactttttg caggccgttc agatagatga tatattgcgc attcaggcac ggattattca
    20041 tcatacgaga cggtcagcta taattgatta cgatatttat catggtcacc agattgtttc
    20101 aaaagcaaat gtgactgtta aaattaatta gaaactagga gaaaagatga taacattaaa
    20161 atcagctcgt gaaatcgaag ctatggacaa ggctggtgat tttctagcaa gtattcatat
    20221 aggcttacgt gatttgatta agccaggcgt agatatgtgg gaagttgaag aatatgtccg
    20281 ccgtcgttgt aaagaagaaa atttccttcc acttcagatt ggggttgacg gtgccatgat
    20341 ggactatcct tatgctacct gttgctctct taacgatgaa gtggctcacg ctttccctcg
    20401 tcattatatc ttgaaagatg gtgatttgct caaagttgat atggttttgg gaggtcccat
    20461 tgctaaatct gacctaaatg tctcaaaatt aaacttcaac aatgttgaac aaatgaaaaa
    20521 atacactcag agttattctg gtggtttagc agactcatgt tgggcttatg ctgttggtac
    20581 accgtccgaa gaagtcaaaa acttgatgga tgtaaccaaa gaagctatgt acaagggtat
    20641 tgagcaagct gttgttggaa atcgtatcgg tgatatcggt gcggctattc aagaatacgc
    20701 tgaaagtcgt ggttacggtg tagtgcgtga tttggttggt catggtgttg gcccaactat
    20761 gcacgaagaa ccaatggttc ctaactatgg tattgcaggt cgtggactcc gtcttcgtga
    20821 aggaatggtc ttaaccattg aaccaatgat caatacaggc gattgggaaa ttgatacaga
    20881 tatgaaaact ggttgggcgc ataagaccat tgacggtgga ttgtcatgtc agtatgaaca
    20941 ccaatttgtc attacgaaag atggacctgt tatcttgact agccaaggtg aagaaggaac
    21001 ttattaataa aaagtgaaaa gactactgga agtttattat gaaaaaatcc agtagatctt
    21061 ttcataataa aacgcattgt atcaagtgtt aggggctgat atcatgcgtt tttctgcttt
    21121 taagattttt tccaactctg tttgtaagcg catcataaca aagggtctag gattcagggc
    21181 tctcctccta tatactatta gtaaagtaaa actaagggag gatattttag tgtcgcagtc
    21241 tattgttcct gtagagattc cacaatattg tcgttttgat tctaaaaaga gaaatggaat
    21301 tctgtttaat gttcgtattg ccaatcttaa atttaccttt tttagattag acttcctgcg
    21361 aaacaaaaca tggtatagta gttctatgaa tgatgaagca agtaaacaac taactgatgc
    21421 acgatttaag cgtcttgttg gtgttcaacg cacgactttt
//
LOCUS       DAVAZV010000036        21413 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVAZV010000036 DAVAZV010000000
VERSION     DAVAZV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21413
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.036"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            89..487
                     /locus_tag="VQT46_001325"
     CDS             89..487
                     /locus_tag="VQT46_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371350.1"
                     /translation="MKSPIPKAPLAHNFGSASIIAHTIHQKFNLKVPNYRQEEDWARM
                     GLPIIRKEISNWHIKTSQYYLEPLYNLLRERLLTQPLLHADETSYRVLESDSQLTYYW
                     TFLSGKAEKQGITLYHHVLIDLFISYFNPL"
     gene            complement(684..1604)
                     /gene="cysK"
                     /locus_tag="VQT46_001326"
     CDS             complement(684..1604)
                     /gene="cysK"
                     /locus_tag="VQT46_001326"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET2371351.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(1889..2524)
                     /locus_tag="VQT46_001327"
     CDS             complement(1889..2524)
                     /locus_tag="VQT46_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET2371352.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVSVNLV"
     gene            2580..3878
                     /locus_tag="VQT46_001328"
     CDS             2580..3878
                     /locus_tag="VQT46_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2371353.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            3875..4537
                     /locus_tag="VQT46_001329"
     CDS             3875..4537
                     /locus_tag="VQT46_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET2371354.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQACQFWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            4617..5165
                     /gene="raiA"
                     /locus_tag="VQT46_001330"
     CDS             4617..5165
                     /gene="raiA"
                     /locus_tag="VQT46_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET2371355.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            5301..7274
                     /locus_tag="VQT46_001331"
     CDS             5301..7274
                     /locus_tag="VQT46_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET2371356.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDALGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNTVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            7271..7723
                     /gene="rplI"
                     /locus_tag="VQT46_001332"
     CDS             7271..7723
                     /gene="rplI"
                     /locus_tag="VQT46_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET2371357.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            7767..9119
                     /gene="dnaB"
                     /locus_tag="VQT46_001333"
     CDS             7767..9119
                     /gene="dnaB"
                     /locus_tag="VQT46_001333"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET2371358.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            9121..9387
                     /locus_tag="VQT46_001334"
     CDS             9121..9387
                     /locus_tag="VQT46_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371359.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            9476..10822
                     /gene="cbpD"
                     /locus_tag="VQT46_001335"
     CDS             9476..10822
                     /gene="cbpD"
                     /locus_tag="VQT46_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET2371360.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKTKSA
                     IKTEPLVSGTVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      10905..11007
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            11078..11368
                     /locus_tag="VQT46_001336"
     CDS             11078..11368
                     /locus_tag="VQT46_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET2371361.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     gene            11331..12089
                     /locus_tag="VQT46_001337"
     CDS             11331..12089
                     /locus_tag="VQT46_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371362.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            12127..13134
                     /locus_tag="VQT46_001338"
     CDS             12127..13134
                     /locus_tag="VQT46_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2371363.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            13134..13862
                     /locus_tag="VQT46_001339"
     CDS             13134..13862
                     /locus_tag="VQT46_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371364.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            13981..14439
                     /locus_tag="VQT46_001340"
     CDS             13981..14439
                     /locus_tag="VQT46_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET2371365.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQVIQEVDRKGK"
     gene            14441..16873
                     /locus_tag="VQT46_001341"
     CDS             14441..16873
                     /locus_tag="VQT46_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2371366.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFMELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALVLGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     ALRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            17515..18168
                     /gene="rr06"
                     /locus_tag="VQT46_001342"
     CDS             17515..18168
                     /gene="rr06"
                     /locus_tag="VQT46_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET2371367.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            18165..19505
                     /gene="hk06"
                     /locus_tag="VQT46_001343"
     CDS             18165..19505
                     /gene="hk06"
                     /locus_tag="VQT46_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET2371368.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILFLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            19588..20115
                     /locus_tag="VQT46_001344"
     CDS             19588..20115
                     /locus_tag="VQT46_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET2371369.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAMVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            20194..>21413
                     /locus_tag="VQT46_001345"
     CDS             20194..>21413
                     /locus_tag="VQT46_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET2371370.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLFLGGVVHAEGVRSGD
                     TPKVTSSGDEVESHLKKILSEIQTQLDRKRHAKTVALINKLQDIKRTYSYKLNVLEEK
                     PKAELTSKTKEELTAAFEQFKKDTLPTEPGKKVAEAEKKVAEAEKKAEDQKEEDRRNY
                     PTNTYKTLELEIAEFDVKVKEAELELLKEKAKKPLNEGTIKQAKEKVESKKAEATRLE
                     NIKTDRKKAEEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPAPKPEKPAPAPKPENP
                     APKPEKPAPAPKPENPAEQPKAEKPADQQAEEDYARRSEEEYNRLTQQQPPKTEKPAQ
                     PSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYL
                     NANGSMATGWLQNNG"
BASE COUNT         6722 a         3563 c         4825 g         6303 t
ORIGIN      
        1 ccaatattag tcggaatctt taaggtactt gatttatgcc atatagcatt gtccataacg
       61 agtaaaagat aatcatctgg ataagcttgt gaaatctcct attcctaaag cccctttagc
      121 gcataacttt ggctcagctt ctattatcgc tcacaccatc catcagaagt ttaatctgaa
      181 ggtacccaat tatcgccaag aagaagattg ggctaggatg ggtttaccaa tcatacgtaa
      241 ggaaatctct aattggcata tcaagacgag tcaatactat ttggagcccc tttataacct
      301 cttgcgagag agactattga ctcagccctt acttcatgcg gatgaaactt cttatagggt
      361 gctagagagt gatagtcagc tgacttacta ctggactttt ttgtctggga aagctgagaa
      421 acaagggatt acgctttacc atcatgtcct aatcgatttg ttcatatctt atttcaatcc
      481 attataaata gtgagaaata tctatcctat cttctagaat gtcttccaaa cgtggaaact
      541 ctcgtaaaca aagaggtttt agaggcctat ttaccatgga ctaaagttgt acaagaaaag
      601 tgcaaataag aaatctccag attaggaact atccgtgagt tctctagtct ggagattttt
      661 caatagactt cgttattgga cggttacaat tcataaagtg ctgtagagag ataacgttca
      721 ccgttatctg gtgctagggc aaggactttt ttacctgtac ctaatttttt ggcaacctcg
      781 atggctccgt agatagctgc agctgaggaa atccctacaa ggaagccttc ttttccacca
      841 atttcacgtc cgagtgcaag agcgtcatct gatgttacac gaacgatacc atcataggct
      901 ttagtatcaa gtgtatcagg aataaatcca gctgagatac cttgaatttt gtgaggacca
      961 ggtttttcac cagatagaat agcagattca tctgcttcta ctgcaaaaac ttgaatgtta
     1021 gaattttctg atttgagtgc atgagaaaca ccagaaatcg ttccaccagt acctactcca
     1081 gcaacaaagg catctaatcc atctttaccg aaagcagcta gtatctcagc tcctgttgtt
     1141 ctttcgtgta cttctggatt agctggattg tcaaattgaa gaggaaggaa accatcacgt
     1201 tcagcagcga tttcttgagc cttagcaata gcacctttca ttccctcgct accaggagtt
     1261 aggacgagtt cagcaccata agcttggata attttacgtc gttctacact catagtttca
     1321 ggcataacga tgacgacttt atacccttta gcagcaccta cccatgaaag tccaataccg
     1381 gtgtttccac ttgttgcttc aacaatagta gaaccaagtt tcagaatacc atcttgttca
     1441 gctttttcaa tcatgctaag ggcaatacgg tcttttacag atgaaccagg attaaatgct
     1501 tcaagcttta tatagacgtc tgcagcacct tctggcacga tgttgttaag tttaacaatc
     1561 ggtgtttgac cgattaattc agtaatgttg ttataaatag acatatgaat acctctttgt
     1621 ataagatatc tttagtataa cgctatccat accatttgta aaatatagaa atcctatcga
     1681 agcgatagga tttctatata tcatagatca aagtcattaa ttttcaagtg attgcgttca
     1741 gttaattcta gtaaataggt gtgaaggaaa acgatatcag gtttcgtttg aattgcttca
     1801 ttttctagta tattttggta cgcatctttt tattttgctc gctaaagtag ttgtgagaat
     1861 gtcaacgaaa cgctgtatta ttcattgttt acactaagtt tacagaaact tcaacctctc
     1921 gtaaaccttg gtcagttaaa gtgacttttc cattaaaaaa ctccacaagt gcagctttaa
     1981 tagtttcttt ttcttcttta tcaacataaa tcatcgtatc gacttgatct gtaaagtttg
     2041 tatccagctc catgagatca tgttctttaa ggaagttact gtactcttgg tactgagcat
     2101 aagacatttg aatagcaatg ccagcctgtt cttttatttc aataatacca atttctttga
     2161 cagctaaggc gacactgccg gcgtaagcac gaattagtcc tccagcgcct agtttaatac
     2221 caccaaagta gcgtgtcacg accacacaga cattggtgag attgtgattt tctagtaccc
     2281 caagcatggg aacaccagca gtaccactag gctcaccatc atcacttgta cgtttaattt
     2341 cactacgttc tccaataata aaggcagagc agttatgtgt cgctttgtag tgttcttttt
     2401 tgatggcagt aatgaagtca cgagcctctt cttcgctata aacacgcttg gcatggcaga
     2461 taaagcgaga ttttttgatt tcttcttgga cttggccgtc ctctttaatt gtcctaaatt
     2521 ccatgattta attgtactaa aaaataatct aaagtgctag tttttacgaa taaagaagta
     2581 tgaaagtaaa tttagattat ctcggtcgtt tatttactga gaatgaatta acagaagaag
     2641 aacgtcagtt ggcggagaaa cttccagcaa tgagaaagga gaaggggaaa cttttctgtc
     2701 aacgttgtaa tagtactatt ctagaagaat ggtatttgcc catcggtgct tactattgtc
     2761 gagagtgctt gctgatgaag cgagtcagaa gtgatcaaac tttatactat tttccgcagg
     2821 aggattttcc gaagcaagat gttctcaaat ggcgcggcca attaactcct tttcaagaga
     2881 aggtgtcaga gggactgctt caagcagtag acaagcaaaa gccaacctta gttcatgcgg
     2941 taacaggagc tggaaagaca gaaatgattt atcaagtagt ggctaaagtg atcaatgcgg
     3001 gtggtgcagt gtgtttggct agtcctcgca tagatgtttg tttggagctg tacaagcgcc
     3061 tgcaacagga tttttcttgc ggtatagctt tgctacatgg agaatcggaa ccttattttc
     3121 gaacaccact agttgttgca acaacccatc agttattgaa gttttatcaa gcttttgatt
     3181 tgctgatagt ggatgaagta gatgcttttc cttatgttga taatcccacg ctttaccacg
     3241 ctgtcaagaa tagtgtaaag gagaatggat tgagaatctt tttaacagcg acttcgacca
     3301 atgagttaga taaaaaggtc cgtttaggag aactaaaaag actgagttta ccgagacggt
     3361 ttcatggaaa tccgttgatt attccaaaac caatttggtt atcggatttt aatcgctact
     3421 tagacaagaa tcgtttgtca ccaaagttaa agtcctatat tgagaagcag agaaagacag
     3481 cttatccgtt actcattttt gcttcagaaa ttaagaaagg ggagcagtta gaagaaatct
     3541 tacaggagca atttccaaat gagaaaattg gctttgtatc ttctgtaaca gaggatcgat
     3601 tagagcaagt acaagctttt cgagatggag aactgacaat acttatcagt acgacaatct
     3661 tggagcgtgg agttaccttc ccttgtgtgg atgttttcgt aatagaggcc aatcatcgtt
     3721 tgtttaccaa gtctagtttg attcagattg gtggacgagt tggacgaagc atggatagac
     3781 cgacaggaga tttgcttttc ttccatgatg ggttaaatgc ttcaatcaag aaggcgatta
     3841 aggaaattca gatgatgaat aaggaggctg gtctatgaag tgcttgttat gtgggcagac
     3901 tatgaagact gttttaactt ttagtagtct cttacttctg aggaatgatg actcttgtct
     3961 ttgttcagac tgtgattcta cttttgaaag aattggggaa gagaactgtc caaattgtat
     4021 gaaaacagag ttgtcaacaa agtgtcaagc ttgtcaattt tggtgtaaag aaggagttga
     4081 agtcagtcat agagcgattt ttacttacaa tcaagctatg aaggattttt tcagtcggta
     4141 taagtttgat ggagacttcc tgttaagaaa agttttcgct tcatttttaa gtgaggagtt
     4201 gaaaaagtac aaagagtatc aatttgttgt aattccccta agtcctgata gatatgctaa
     4261 cagaggattt aatcaggttg agggcttggt agaggcagca ggctttgagt atctagattt
     4321 attagagaaa agagaagaga gagccagttc ttctaaaaat cgttcagagc gcttggggac
     4381 agaacttcct ttctttatta aaagtggagt cactattcct aaaaaaatcc tacttataga
     4441 tgatatctat actacaggag caactataaa tcgtgttaag aaactgttgg aagaagctgg
     4501 tgctaaggat gtaaaaacat tttcccttgt aagatgagga aaaaatttgc aaaaatagaa
     4561 tgaaagcgtt ataataaaat cataaaaaca aaaatgttta gaaagaaggt actcatatga
     4621 ttaaatatag tatccgtggt gaaaacctag aagtaacaga agcaattcgt gattatgtag
     4681 tttctaaact cgaaaagatc gaaaagtact tccaaccaga acaagagttg gatgcccgaa
     4741 ttaacttaaa agtttatcgt gaaaaaacgg ctaaagtgga agtaacgatt ccgcttggat
     4801 ctattactct ccgcgcagaa gatgtatctc aagatatgta tggttcaatt gaccttgtaa
     4861 ctgataaaat tgaacgtcag attcgtaaaa ataaaacaaa aatcgagcgt aaaaataaaa
     4921 ataaggtagc aactggtcaa ttatttacag atgctttggt ggaagattca aatattgtcc
     4981 agtctaaagt tgttcgttca aaacaaattg atttaaaacc aatggatttg gaagaagcaa
     5041 ttctacaaat ggatttattg gggcatgatt tctttatcta tgtggatgtt gaagatcaga
     5101 caaccaatgt gatttatcgt cgtgaggatg gcgaaattgg tttgttagag gttaaagaat
     5161 cttaatttca atatgtgtaa aggtaggttt actgaattgt aaactacctt tttcttataa
     5221 ttgatagaat tactgattac acttttaaaa agtcgctttt tgaggggtat tatggtataa
     5281 tgggtgccaa gaggttttga atgaaaaaat tttatgtaag tccaattttt cctattctag
     5341 taggattgat tgcgtttgga gtcttatcca ctttcattat ttttgttaat aataatctgt
     5401 tgacggtttt aattttgttt ctttttgtag gaggctatgt ttttttattt aagaaactga
     5461 gagtgcatta tacaaggagt gatgtagaac agatacagta tgtaaaccac caagcggaag
     5521 aaagtttgac agctctattg gaacagatgc ctgtaggtgt tatgaaattg aatttatctt
     5581 ctggagaggt tgagtggttt aatccctatg ctgaattgat tttgaccaag gaagatggtg
     5641 attttgattt agaagctgtt caaacgatta tcaaggcttc agtaggaaat ccgtctactt
     5701 atgccaagct tggtgagaag cgttatgctg ttcatatgga tgcttcttcc ggtgttttgt
     5761 attttgtaga tgtatccagg gaacaagcca taacagatga attggtaaca agtcgaccag
     5821 tgattgggat tgtctctgtg gataattatg atgatttgga ggatgcaact tctgagtcag
     5881 atattagtca aatcaatagt tttgtagcta attttatatc agagttttca gaaaaataca
     5941 tgatgttttc tcgtcgggta agtatggatc gattttatct atttactgac tacacggtgc
     6001 ttgagggctt gatgaatgat aaattttctg ttattgatgc tttcagagaa gagtcgaaac
     6061 agagacagtt gcccttgacc ttaagtatgg gattttctta tggcgatgga aatcatgatg
     6121 agatagggaa agttgctttg ctcaatttga acttggctga agtacgtggt ggcgaccagg
     6181 tggttgttaa ggaaaacgac gaaacgaaaa atccagttta ttttggtggt gggtctgctg
     6241 cttcaatcaa gcgtacacgg actcgtacgc gcgctatgat gacagctatt tcagataaga
     6301 ttcggagtgt agatcaggtt tttgtagtcg gtcacaaaaa tttagacatg gatgctttgg
     6361 gctctgctgt aggtatgcag ttgttcgcca gcaatgtgat tgaaaatagc tatgctcttt
     6421 atgatgaaga acaaatgtct ccagatattg aacgagctgt ttcattcata gaaaaagaag
     6481 gagttacgaa gttgttgtct gttaaggatg cattggggat ggtgaccaat cgttctttgt
     6541 tgattcttgt agaccattca aagacagcct taacattatc aaaagaattt tatgatttat
     6601 ttacccaaac cattgttatt gaccaccata gaagggatca ggattttcca gataatacgg
     6661 tcattactta tatcgaaagt ggtgcaagta gtgccagtga gttggtaacg gaattgattc
     6721 agttccagaa ttctaagaaa aatcgtttga gtcgtatgca agcaagtgtc ttgatggctg
     6781 gtatgatgtt ggatactaaa aatttcacct cgcgagtaac tagtcggaca tttgatgttg
     6841 ctagctatct cagaacgcgc ggaagtgata gtattgctat ccaggaaatc gctgcgacag
     6901 attttgaaga atatcgtgag gtcaatgaac ttattttaca ggggcgtaaa ttaggttcag
     6961 atgtactaat agcagaggct aaggacacga aatgctatga tacagttgtt attagtaagg
     7021 cagcagatgc catgttagcc atgtcaggta ttgaagcgag ttttgttctt gcgaagaata
     7081 cacaaggatt tatctctatc tcagctcgaa gtcgtagtaa actgaatgta caacggatta
     7141 tggaagagtt aggcggtgga ggccacttta atttggcagc agctcaaatt aaagatgtaa
     7201 ccttgtcaga agcaggtgaa aaactgacag aaattgtatt aaatgaaata aaggaaaagg
     7261 agaaagaaga atgaaagtaa tctttttagc agatgttaaa ggaaaaggta aaaaaggcga
     7321 aattaaggaa gtaccaacag ggtatgcgca aaactttctt atcaaaaaga atctagccaa
     7381 agaagcgact gctcaagctg taggtgaact tcgtggtaaa caaaaatcgg aagaaaaagc
     7441 tcacgctgag atgattgcag aaggaaaagc aattaaagca caacttgaag cagaagaaac
     7501 tgttgtagaa tttgttgaaa aagttggtcc agatggtcgt acctttggct ctattaccaa
     7561 taagaagatt gcagaagaat tgcaaaaaca atttggaatt aagattgata aacgtcatat
     7621 tcaagtacaa gctccgattc gagcggttgg tttgattgat gtgccagtga aaatctatca
     7681 agatatcaca agtgtaatca atcttcgtgt gaaagaagga taagtttaca ccttcttgac
     7741 aagattgtaa aaggaaggga agtctgatgg cagaagtaga agagttacga gtacaacctc
     7801 aagatatctt agctgagcaa tccgttttag gggctatctt tattgatgag agtaaacttg
     7861 tttttgtgcg agaatacatt gagtctcggg acttttttaa gtatgcccat cgtttgattt
     7921 tccaagccat ggtcgattta tccgatcgtg gtgatgccat agatgcaaca acggttcgta
     7981 ctatccttga taatcaaggt gatttacaga atattggtgg cttgtcttac ttggttgaga
     8041 ttgttaattc tgtgccaact tctgctaatg cggagtatta tgctaagatt gttgcagaaa
     8101 aagcaatgct acgtcgttta attgccaagt tgacagagtc tgtcaaccaa gcttacgaag
     8161 cgtcacaacc agctgatgaa attattgctc aggcagaaaa agggctgatt gatgtcagtg
     8221 aaaatgcaaa tcgaagcggg tttaagaaca ttcgagatgt gttgaatctc aactttggaa
     8281 atctggaagc tcgctcgcaa caaacgaccg atattacagg tattgcgaca ggttatcgtg
     8341 atttggatca tatgacaaca ggacttcatg aggaggagtt gattatctta gcagctcgtc
     8401 cagcagttgg taagacagca tttgccttga atatcgctca gaacattggg actaagttgg
     8461 acaaaacggt tgctattttt tcactcgaaa tgggtgcgga aagcttggta gatcgtatgt
     8521 tagctgcaga aggcttagtg gagtcacatt ctatccgtac agggcaattg acagatgagg
     8581 agtggcaaaa atatactatt gctcagggta atctagctaa cgccagtatc tatatcgatg
     8641 atacgccagg tattcggatt acagagattc gttctcgttc tcgtaaattg gctcaagaaa
     8701 ctggaaatct tggtttgatt ttgatagact atttgcaact tatcacggga actggtcgag
     8761 aaaatcgtca acaagaagtt tctgaaattt ctcgtcagtt gaaaatacta gccaaggaat
     8821 tgaaggttcc agtaatcgct ctgagtcagc tttctcgtgg tgtagaacaa cgtcaggaca
     8881 agagaccggt cttgtctgat attcgtgaat ctgggtctat tgagcaggac gctgatatcg
     8941 tagcttttct ctatcgcgat gactactatg aacgtggtgg tgaagaagag gagggtatcc
     9001 caaataataa ggtggaagtt attatcgaga aaaaccgtag tggagctcgt ggaacagtgg
     9061 aattgatttt ccaaaaagaa tacaataaat tttcaagtat ctcaaagagg gaggcataag
     9121 atgtcagatg catttacaga tgtagccaag atgaaaaaaa tcaaagaaga aatcaaggca
     9181 catgagggac aagtcgtaga aatgactttg gagaatggtc gtaagcgcca aaaaaataga
     9241 ttgggtaagc taattgaagt ttatccatct ctatttattg tggagtttgg ggatgtggaa
     9301 ggagataaac aagttaatgt ttacgttgaa tcctttactt actcagatat tcttacagaa
     9361 aagaatttga ttcattatct tgactaaagt gagaaatttt ctcacttttt cttttttctc
     9421 cgaataattt aggtgaaggc aatcatcgct ttatattatt tttcaaggag gaagaatgaa
     9481 aattttaccg tttatagcaa gaggaacaag ttattacttg aagatgtcag ttaaaaagct
     9541 tgttcctttt ttagtagtag gattgatgct agcagctggt gatagtgtct atgcctattc
     9601 cagaggaaat ggatcgattg cgcgtgggga tgattatcct gcttattata aaaatgggag
     9661 ccaggagatt gatcagtggc gcatgtattc tcgtcagtgt acttcttttg tagcctttcg
     9721 tttgagtaat gtcaatggtt ttgaaattcc ggcagcttat ggaaatgcga atgaatgggg
     9781 acatcgtgct cgtcgggaag gttatcgtgt agataataca ccgacgattg gttccattac
     9841 ttggtctact gcaggaactt atggtcatgt tgcctgggtg tcaaatgtaa tgggagatca
     9901 gattgagatt gaggaatata actatggtta tacagaatcc tataataaac gagttataaa
     9961 agcaaacacg atgacaggat ttattcattt taaagatttg gatggtggca gtgttgggaa
    10021 tagtcaatcc tcaacttcaa caggcggaac tcattatttt aagaccaagt ctgctattaa
    10081 aactgaaccc ctagttagtg caactgtgat tgattactat tatcctggag agaaggttca
    10141 ttatgatcaa attctcgaaa aagacggcta caagtggttg agttatactg cctataatgg
    10201 aagctatcgt tatgttcaat tggaggctgt gaataaaaat cctctaggta attctgttct
    10261 ttcttcaaca ggtggaactc attattttaa gaccaagtct gctatcaaaa ctgaacccct
    10321 agttagcgga actgtgattg attactatta tcctggggag aaggttcatt atgatcagat
    10381 acttgaaaaa gacggctaca agtggttgag ttatactgcc tataatggaa gtcgtcgcta
    10441 tatacagcta gagggagtga cttcttcaca aaattatcag aatcaatcag gaaatatctc
    10501 tagctatgga tccaataata gttcaactgt cggttggaag aaaataaatg gtagttggta
    10561 tcatttcaaa tcaaatggtt ctaaatcaac aggatggctg aaagacggtt ctagctggta
    10621 ttatttgaaa ttatctggtg aaatgcagac aggatggtta aaggagaatg gctcgtggta
    10681 ttatctgggt agttcagggg caatgaaaac aggctggtac caggtctctg gtaagtggta
    10741 ttattcttac tcttcaggcg ccttagctgt taatacgacg gtggatggct acagagtaaa
    10801 cagtgatgga gaacgagtat agaaaattgg agtaggagaa atttcctgct cttttctgta
    10861 agcagtttcc ttgacatttt tcttattttg cgctatcata tatacatata atatatggga
    10921 gtctgtgtac agtctgagag gaagtgttaa acttcgaccg cacctgatct gggtaatgcc
    10981 agcggaggga acgatactta gtctaatttt gcaccttttc catgtatggt aaaggttttt
    11041 ctttttttta aaaggaaaac gagaagagga ggttcttatg aaagcaagca ttgccttgca
    11101 agttttaccc ctagcacagg ggattgatcg gatagctgtt attgatcagg tcattgctta
    11161 tctgcaaact caagaagtga cgatggtagt gacaccattt gaaacggtct tggaagggga
    11221 gtttgatgag cttatgcgca ttctaaaaga agcgctggaa gtggcagggc aggaggcaga
    11281 caatgtcttt gccaatgtca aaataaatgt aggagagatt ttaagtattg atgagaaact
    11341 tgaaaagtat actgagacga cacattagtc tattgggctt tctcggagta ttgtcaatct
    11401 ggcagttagc aggttttctt aaacttctcc ccaagtttat cctgccgaca cctcttgaaa
    11461 ttctccagcc ctttgttcgt gacagagaat ttctctggca ccatagctgg gcgaccttga
    11521 gagtggcttt actggggctg attttgggag ttttgattgc ctgtcttatg gctgtgctca
    11581 tggatagttt gacttggctc aatgacctga tttaccctat gatggtggtc attcagacca
    11641 ttccgaccat tgccatagct cctatcctgg tcttgtggct gggttatggg attttgccca
    11701 agattgtctt gattatctta acaacaacct ttcccatcat cgttagtatt ttggacggtt
    11761 ttaggcattg tgacaaggat atgctgactt tgtttagtct gatgcgagca aacccttggc
    11821 aaatcctgtg gcattttaaa atcccggtta gcctgcctta cttttatgca ggtctgaggg
    11881 tcagtgtctc ctacgccttt atcacaactg tggtatctga gtggttggga ggttttgaag
    11941 gtcttggtgt ttatatgatt cagtctaaaa aactgtttca gtatgatacc atgtttgcca
    12001 ttattattct ggtgtcgatt atcagtcttt tgggtatgaa gctggtcgat atcagtgaaa
    12061 aatatgtgat taaatggaaa cgtacttaaa atagagcgtt tttgaaaaag aaaagaggaa
    12121 atcaaaatga agaaaacatg gaaagtgttt ttaacgcttg taacagctct tgtagctgtt
    12181 gtgcttgtgg cctgtggtca aggaactgct tctaaagaca acaaagaggc agaacttaag
    12241 aaggttgact ttatcctaga ctggacacca aataccaacc acacagggct ttatgttgcc
    12301 aaggaaaaag gttatttcaa agaagctgga gtggatgttg atttgaaatt gccaccagaa
    12361 gaaagttctt ctgacttggt tatcaacgga aaggcaccat ttgcagtgta tttccaagac
    12421 tacatggcta agaaattgga aaaaggagca ggaatcactg ccgttgcagc tattgttgaa
    12481 cacaatacat caggaatcat ctctcgtaaa tctgataatg taagcagtcc aaaagacttg
    12541 gttggtaaga aatatgggac atggaatgac ccaactgaac ttgctatgtt gaaaaccttg
    12601 gtagaatctc aaggtggaga ctttgagaag gttgaaaaag taccaaataa cgactcaaac
    12661 tcaatcacac cgattgccaa tggcgtcttt gatactgctt ggatttacta cggttgggat
    12721 ggtatccttg ctaaatctca aggtgtagat gctaacttca tgtacttgaa agactatgtc
    12781 aaggagtttg actactattc accagttatc atcgcaaaca acgactatct gaaagataac
    12841 aaagaagaag ctcgcaaagt catccaagcc atcaaaaaag gctaccaata tgccatggaa
    12901 catccagaag aagctgcaga tattctcatc aagaatgcac ctgaactcaa ggaaaaacgt
    12961 gactttgtca tcgaatctca aaaatacttg tcaaaagaat acgcaagcga caaggaaaaa
    13021 tggggtcaat ttgacgcagc tcgctggaat gctttctata aatgggataa agaaaatggt
    13081 atccttaaag aagacttgac agacaaaggc ttcaccaacg aatttgtgaa ataatgacag
    13141 aaattagact agagcatgtc agttatgcct atggtcagga gaggatttta gaggatatca
    13201 acctacaggt gacttcaggc gaagtggttt ccattctagg cccaagtggt gttggaaaga
    13261 ccaccctctt taatctaatc gctgggattt tagaagttca gtcagggaga attgtccttg
    13321 atggtgaaga aaatcccaag gggcgcgtga gttatatgtt gcaaaaggat ctgctcttgg
    13381 agcacaagac ggtgcttgga aatatcattc tgcccctctt gattcaaaag gtggataagg
    13441 cagaagctat ttcccgagcg gataaaattc ttgcgacctt ccagctgaca gctgtaagag
    13501 acaagtatcc tcatgaactt agcggtggga tgcgccagcg tgtagcctta ctccggacct
    13561 acctttttgg gcacaagctc tttctcttag atgaggcctt tagcgccttg gatgagatga
    13621 caaagatgga actccacgct tggtatcttg agattcacaa acagttgcag ctaacaaccc
    13681 tgatcatcac gcatagtatt gaggaggccc tcaatctcag cgaccgtatc tatatcttga
    13741 aaaatcgccc tgggcagatt gtttcagaaa ttaaactaga ttggtctgaa gatgaggaca
    13801 aggaagtcca aaagattgcc tacaaacgtc aaatcttggc agaattaggc ttagataagt
    13861 agaaaaatag ggagttggtg aagattatcc tttaccagcg ccctttttct tttaaaaatg
    13921 agaaaatttc ggtataatag tcaaacaagg tcaaggttta aagagagagg tgggtttgtt
    13981 atgagattta aaaatacatc ggatcatatt gaggcctaca tcaaggcgat tttagatcaa
    14041 tctggtatcg tggagttgca acggagtcag ttggcagata cctttcaggt tgttcctagt
    14101 cagattaact acgtgatcaa gacacgcttt acggaaagta gaggctactt ggttgaaagt
    14161 aagcgtggtg gcggaggcta cattcgtata ggacggattg agttttctag tcatcatgaa
    14221 atgctccggg agctgcttta ctcgattggt gagcgagtca gtcaagaaat ttatgaggat
    14281 attctccagc ttttggttga gcaggaattg atgaccaagc aggagatgaa tttgctagaa
    14341 tcagtagctt tggatcgcgt tttaggagaa gaagctccag ttgttcgagc aaacatgcta
    14401 cgtcaggtca tacaagaggt agatagaaaa gggaagtaag atgaactatt caaaagcatt
    14461 gaatgaatgt atcgaaagtg cctacatggt tgctggacat tttggagctc gttatctaga
    14521 gtcgtggcac ttgttgattg ccatgtctaa tcacagttat agtgtagcag gggcaacttt
    14581 aaatgattat ccgtatgaga tggaccgttt agaagaggtg gctttggaac tgactgaaac
    14641 ggactatagc caggatgaaa cctttatgga attgccgttc tcccgtcgtt tgcaggttct
    14701 ttttgatgaa gcagagtatg tagcgtcagt ggtccatgct aaggtactag ggacagagca
    14761 cgtcctctat gcgattttgc atgatggcaa tgccttggcg actcgtatct tggagagggc
    14821 tggtttttct tatgaagaca agaaagatca ggtcaagatt gctgctcttc gtcgaaattt
    14881 agaagaacgg gcaggctgga ctcgtgaaga tctcaaggct ttacgccaac gccatcgtac
    14941 tgtggctgac aaacaaaatt ctatggccaa tatgatgggc atgccgcaga ctcctagtgg
    15001 tggtctcgag gactatacgc atgatttgac agagcaagcg cgttctggca agttagaacc
    15061 agtcatcggt cgggacaagg aaatctcacg tatgattcaa atcttgagcc gtaagactaa
    15121 gaacaaccct gtcttggttg gggatgctgg tgtcgggaaa acagctctgg tgcttggtct
    15181 tgctcagcgt attgccagtg gtgatgtgcc tgcggaaatg gctaagatgc gcgtgttaga
    15241 acttgatttg atgaatgtcg ttgcagggac acgcttccgt ggtgactttg aagaacgcat
    15301 gaataatatc atcaaggata ttgaagaaga tggccaagtc atcctcttta tcgatgaact
    15361 ccacaccatc atgggttctg gtagcgggat tgattcgact ctggatgcgg ccaatatctt
    15421 gaaaccagcc ttggcgcgtg gagctttgag aacggttggt gccaccactc aggaagaata
    15481 tcaaaaacat atcgaaaaag atgcggctct ttctcgtcgt ttcgctaaag tgacgattga
    15541 agaaccaagt gtggcagata gtatgactat tttacaaggt ttgaaggcga cttatgagaa
    15601 acatcaccgt gtacaaatca cagatgaagc ggttgaaaca gcggttaaga tggctcatcg
    15661 ttatttaacc agtcgtcact tgccagactc tgctatcgac ctcttggacg aagcagcagc
    15721 aacagtgcaa aataaggtaa agtatgtaaa agcagacgat tcagatttga gtccagctga
    15781 taaggccctg atggatggca agtggaaaca ggcagcccag ctaatcgcaa aagaagagga
    15841 agtacctgtc tacaaagact tggtgacaga gtctgatatt ttgaccacct tgagtcgctt
    15901 gtcaggaatc ccagttcaaa aactgactca aacggatgct aagaagtatc taaatcttga
    15961 agcagaactc cataaacgtg tcatcggtca agatcaagct gtttcaagca ttagtcgtgc
    16021 gattcgccgt aatcagtcag gaattcgcag tcacaagcgt ccgatcggtt cctttatgtt
    16081 cctaggaccc acaggtgtcg gtaagaccga gttggccaag gctttggcag aagttctctt
    16141 tgatgacgaa tcagccctta tccgctttga tatgagtgag tatatggaga aattcgcagc
    16201 cagccgtcta aatggagctc ctccaggcta tgtgggttac gaagaaggtg gagagttgac
    16261 agagaaggtt cgcaataaac cctattccgt tctcctcttt gatgaggtag agaaggccca
    16321 cccagatatt tttaatgttc tcttgcaggt tctggatgac ggtgttttga cagatagcaa
    16381 gggacgcaag gtcgattttt caaataccat tatcattatg acatcgaacc taggtgcgac
    16441 tgcccttcgt gatgataaga ctgttggttt tggggctaag gatattcgtt ttgaccagga
    16501 aaatatggaa aaacgcatgt ttgaagaact gaaaaaagct tatagaccgg aattcatcaa
    16561 ccgtattgat gagaaggtgg tcttccatag cctatctagt gaccatatgc aggaagtggt
    16621 gaagattatg gtcaagcctt tagtggcaag tttggctgaa aaaggcattg acttgaaatt
    16681 acaagcttca gctctgaaat tgttagcaaa tcaaggatat gacccagaga tgggagctcg
    16741 cccacttcgc agaaccctgc aaacagaagt ggaggacaag ttggcagaac ttcttcttaa
    16801 gggagattta gtggcaggca gcacacttaa gattggtgtc aaagcaggcc agttaaaatt
    16861 tgatattgca taaaagaata aaagtatcag catctgacca taagtcacag tggagtgaaa
    16921 ctcaatgaaa atcaaagagc aaactaggca gctagccgca ggttgctcaa aacactggtt
    16981 tgaggttgca gatagagctg acgtggtttg aagagatttt cgaagagtat gaaactaaaa
    17041 cctatagctt ctaaacgatc cgtggttttc accattcaac acaaaattca tatgtttatt
    17101 accctccgtc gtatttgtct tagagcgtgt gtagtagaaa aagagcagtc ttatctgaaa
    17161 tttttattct ttcaaaagag acctgtttct tttttgcatg tcaaatccgt tctagctggt
    17221 atttgaaaaa tcaaactaat attcaatgaa aatcaaagaa caaactaggc agctagccac
    17281 aggttgctca aaacactgtt ttgaggttgt agatagagct gacgtagttt gaagagattt
    17341 tcgaagagta taagctgcaa gatgaatgat tttcttgtat tgacgttgtt gttgacaaaa
    17401 agtagcggat aaatgaaatc cattccatta tcatagatga taggctggta ggaaattttc
    17461 aaatagcata caggaaatag atgtatggag ttctggtagt agaaagggag agagatgaac
    17521 attttagttg cagatgacga ggaaatgatt agagaaggaa ttgcagcatt tctgacagaa
    17581 gagggttatc atgtcattat ggctaaggat ggacaagagg tcttggaaaa atttcaagat
    17641 ctccctatcc atctcatggt attggattta atgatgccta ggaagagtgg ttttgaagtg
    17701 ttaaaagaaa tcaatcaaaa gcacgatatt cctgtcatcg tcttgagtgc tctgggagat
    17761 gaaactactc agtcacaggt atttgatctc tatgctgatg atcatgtgac aaaacctttt
    17821 tctttggtac tgcttgtcaa gcgtattaag gcgcttatca gacgttacta cgtcatagag
    17881 gatatttggc gatatcagga tgtaacagtg gattttacct cttacaaagc acattataaa
    17941 aatgaagaaa ttgatctcaa accaaaggaa ttactggtac taaagtgttt gattcagcat
    18001 aaaaatcaag ttttaagtag agagcagata ttggaagaaa tttcaaaaga tgtagctgat
    18061 ttaccttgtg atagggtcgt tgatgtctat attcgtactc ttcgcaaaaa attagcttta
    18121 gattgtatcg tgactgtgaa aaatgttggg tataagatta gcttatgata aaaaatccta
    18181 aattattaac caagtctttt ttaagaagtt ttgcaattct aggtggtgtt ggtctagtca
    18241 ttcatatagc tatttatttg acctttcctt tttattatat tcaactggag ggggaaaagt
    18301 ttaatgagag cgcaagagtg tttacggagt atttaaagac taagacatct gatgaaattc
    18361 caagcttact ccagtcttat tcaaagtcct tgaccatatc tgctcacctt aaaagagata
    18421 ttgtagataa gcgactccct cttgtgcatg acttggatat taaagatgga aagctatcaa
    18481 attatatcgt gatgttagat atgtctgtta gtacagcaga tggtaaacag gtaacagtgc
    18541 aatttgttca cggggtggat gtctacaaag aagcaaagaa tattttgttt ttgtatcttc
    18601 catatacatt tttggttaca attgcttttt cctttgtttt ttcttatttt tatactaaac
    18661 gcttgctcaa tcctcttttt tacatttcag aagtgactag taaaatgcaa gatttggatg
    18721 acaatattcg ttttgatgaa agtaggaaag atgaagttgg tgaagttgga gaagttggaa
    18781 aacagattaa tggtatgtat gagcacttgt tgaaggttat tcatgagttg gaaagtcgta
    18841 atgagcaaat tgtaaaattg caaaatcaaa aggtttcctt tgtccgtgga gcatcacatg
    18901 agttgaaaac ccctttagcc agtcttagaa ttatcctaga gaatatgcag cataatattg
    18961 gagattacaa agatcatcca aaatatattg caaagagtat aaataagatt gaccagatga
    19021 gccacttatt ggaagaagta ctggagtctt ctaaattcca agagtggaca gagtgtcgtg
    19081 agaccttgac tgttaagcca gttttagtag atattttatc acgttatcaa gaattagctc
    19141 attcaatagg tgttacaatt gaaaatcaat tgacagatgc taccagggtc gtcatgagtc
    19201 ttagggcatt ggataaggtt ttgacaaacc tgattagtaa tgcaattaaa tattcagata
    19261 aaaatgggcg cgtaatcata tccgagcaag atggctatct ctctatcaaa aatacatgtg
    19321 cgcctctaag tgaccaagaa ctagaacatt tatttgatat attctatcat tctcaaatcg
    19381 tgacagataa ggatgaaagt tccggtttgg gtctttacat tgtgaataat attttagaaa
    19441 gctatcaaat ggactatagt tttctccctt atgaacacgg tatggaattt aagattagct
    19501 tgtagacaga ttagtttttt attaaagttc atatagggtt aacataagtg tgttattctt
    19561 tgtgtagata aaagaaagga tactaatatg gtattagcga ttattttagt aacattcttt
    19621 attcgattga tttttttaaa gcgttcgata gagaatgaga aacgaatcct tagcaatggc
    19681 gggaaagaat ttggagttga gaatacaaaa cgattaacta tggctcatat tgttttttat
    19741 ctctcttgct tggttgaggc aatggtgcac aagacaattt ttgatggcat gggcatggtt
    19801 ggtttagtct tgcttatttt ttctatgctg atgttaatgt tggtgattca cttgttggga
    19861 gatatttgga cagtgaagct tatgcttgtc aataatcaca aatatgtaga tcatatcttg
    19921 tttaggacag taaaacatcc taattacttt ttaaatattc ttcctgagtt gattggcttg
    19981 accttgttga gtcatgctta tgtgactttt gttttagttt ttccagttta tgcagttatt
    20041 ttgtatcgac gaatagctga agaggaaaag ctattacatg aagttataat cccaaatgga
    20101 agcataaaga gataaataca aaattcgatt tatatacagt tcatattgaa gtgatatagt
    20161 aaggttaaag aaaaaatata gaaggaaata aacatgtttg catcaaaaag cgaaagaaaa
    20221 gtacattatt caattcgtaa atttagtatt ggagtagcta gtgtagtagt tgctagcttg
    20281 ttcttaggag gagtagttca tgcagaaggg gttagaagtg gggatacccc caaggttaca
    20341 tctagtgggg atgaagtcga gtcgcatcta aaaaaaatat tgagtgagat ccaaacacaa
    20401 ttagatagaa aacgacatgc caaaactgta gcgctaatta acaagttgca agacattaag
    20461 agaacgtatt cgtataaatt aaatgtttta gaagagaagc cgaaagctga gttgacgtca
    20521 aaaacaaaag aagagttaac cgcagctttt gagcaattta aaaaagatac attaccaaca
    20581 gaaccaggaa aaaaggtagc agaagctgag aagaaggttg cagaagctga gaaaaaagcc
    20641 gaggatcaaa aagaagaaga tcgtcgtaac tacccaacca atacttacaa aacgcttgaa
    20701 cttgaaattg ctgagttcga tgtgaaagtt aaagaagcgg agcttgaact attaaaagag
    20761 aaagctaaga aacctttaaa cgagggcaca attaagcaag caaaagagaa agttgagagt
    20821 aaaaaagctg aggctacaag gttagaaaac atcaagacag atcgtaaaaa agcagaagaa
    20881 gaagctaaac gaaaagcagc agaagaagat aaagttaaag aaaaaccagc tgaacaacca
    20941 caaccagcgc cggctcctca accagaaaaa ccagctccaa aaccagaaaa accagctcca
    21001 gctccaaaac cagagaatcc agctccaaaa ccagaaaaac cagctccagc tccaaaacca
    21061 gagaatccag ctgaacaacc aaaagcagaa aaaccagctg atcaacaagc tgaagaagac
    21121 tatgctcgta gatcagaaga agaatataat cgcttgactc aacagcaacc gccaaaaact
    21181 gaaaaaccag cacaaccatc tactccaaaa acaggctgga aacaagaaaa cggtatgtgg
    21241 tacttctaca atactgatgg ttcaatggcg acaggatggc tccaaaacaa tggctcatgg
    21301 tactacctca acagcaatgg cgctatggcg acaggatggc tccaaaacaa tggttcatgg
    21361 tactatctaa acgctaatgg ttcaatggca acaggatggc tccaaaacaa tgg
//
LOCUS       DAVAZV010000037        21312 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVAZV010000037 DAVAZV010000000
VERSION     DAVAZV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21312)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21312)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21312
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.037"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(57..176)
                     /locus_tag="VQT46_001346"
     CDS             complement(57..176)
                     /locus_tag="VQT46_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2371371.1"
                     /translation="MDFKSFIIGLVVGIFGPYMYNLIRKIFSKFPKKDTDSTP"
     gene            complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQT46_001347"
     CDS             complement(179..409)
                     /gene="blpU"
                     /locus_tag="VQT46_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET2371372.1"
                     /translation="MDTKMMSQFSVMDTEMLACVEGGGCNWGDFAKAGVGGAAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQT46_001348"
     CDS             complement(478..747)
                     /gene="blpJ"
                     /locus_tag="VQT46_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpJ"
                     /protein_id="HET2371373.1"
                     /translation="MNTKMLSQLEVMDTEMLAKVEGGYSSTDCQNALITGVTTGIITG
                     GTGAGLATLGVAGLAGAFVGAHIGAIGGGLTCLGGMVGDKLGLSW"
     gene            complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQT46_001349"
     CDS             complement(1214..1411)
                     /gene="blpI"
                     /locus_tag="VQT46_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpI"
                     /protein_id="HET2371374.1"
                     /translation="MNTKMMEQFSVMDNEELEIVSGGRGNLGSAIGGCIGAVLLAAAT
                     GPITGGAATLICVGSGIMSSL"
     gene            1693..2280
                     /locus_tag="VQT46_001350"
     CDS             1693..2280
                     /locus_tag="VQT46_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2371375.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
                     SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG"
     gene            2273..3862
                     /locus_tag="VQT46_001351"
                     /pseudo
     CDS             2273..3862
                     /locus_tag="VQT46_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864064.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            3873..5234
                     /locus_tag="VQT46_001352"
     CDS             3873..5234
                     /locus_tag="VQT46_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET2371376.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMDESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSGEDEFGYHNTFMNFTKQSHDIELGITKTN
                     TEVSNQANLANSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLLLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            5291..5446
                     /gene="blpC"
                     /locus_tag="VQT46_001353"
     CDS             5291..5446
                     /gene="blpC"
                     /locus_tag="VQT46_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET2371377.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FHQPIQL"
     gene            complement(5490..6830)
                     /locus_tag="VQT46_001354"
     CDS             complement(5490..6830)
                     /locus_tag="VQT46_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2371378.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNTYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNIRDKALKSLLAGKFLKARDKNIVFNVEVPEEI
                     QVEGMSLLDFLTVVSILCDNAIEASVEACQPHVSIAFLKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6844..7581)
                     /locus_tag="VQT46_001355"
     CDS             complement(6844..7581)
                     /locus_tag="VQT46_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2371379.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7586..7924)
                     /locus_tag="VQT46_001356"
     CDS             complement(7586..7924)
                     /locus_tag="VQT46_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2371380.1"
                     /translation="MKHMIIQTQKTVYKVNVDDIYYIQTHPTKAHTVQIVTEEASFNM
                     LQNLSNLENQYGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8201..8530
                     /locus_tag="VQT46_001357"
     CDS             8201..8530
                     /locus_tag="VQT46_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET2371381.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8698..9747)
                     /locus_tag="VQT46_001358"
     CDS             complement(8698..9747)
                     /locus_tag="VQT46_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371382.1"
                     /translation="MKDLFLKRKQAFRKECLCYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEAIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(9744..10475)
                     /locus_tag="VQT46_001359"
     CDS             complement(9744..10475)
                     /locus_tag="VQT46_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371383.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10543..10953
                     /locus_tag="VQT46_001360"
     CDS             10543..10953
                     /locus_tag="VQT46_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET2371384.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMNATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10963..11250
                     /locus_tag="VQT46_001361"
     CDS             10963..11250
                     /locus_tag="VQT46_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371385.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIIDQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            11412..11651
                     /locus_tag="VQT46_001362"
     CDS             11412..11651
                     /locus_tag="VQT46_001362"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371386.1"
                     /translation="MHHNLGNSYSIKIKKQTRKLGTDCSKHRFKVVDRTDEVSSKHCF
                     EVVDRTDEVSNHTHDKPTLTWFEEIFEEYHSPFHN"
     gene            complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQT46_001363"
     CDS             complement(12001..13137)
                     /gene="dnaJ"
                     /locus_tag="VQT46_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET2371387.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13342..13695)
                     /locus_tag="VQT46_001364"
     CDS             complement(13342..13695)
                     /locus_tag="VQT46_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371388.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDHTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQT46_001365"
     CDS             complement(13708..15531)
                     /gene="dnaK"
                     /locus_tag="VQT46_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET2371389.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQT46_001366"
     CDS             complement(16011..16535)
                     /gene="grpE"
                     /locus_tag="VQT46_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET2371390.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQT46_001367"
     CDS             complement(16562..17596)
                     /gene="hrcA"
                     /locus_tag="VQT46_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET2371391.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTGLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17760..18269)
                     /locus_tag="VQT46_001368"
     CDS             complement(17760..18269)
                     /locus_tag="VQT46_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET2371392.1"
                     /translation="MNSRVEFRIFTIVDLDKEEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTTTFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            18877..20814
                     /locus_tag="VQT46_001369"
                     /pseudo
     CDS             18877..20814
                     /locus_tag="VQT46_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399214.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            20812..21312
                     /locus_tag="VQT46_001370"
                     /pseudo
     CDS             20812..21312
                     /locus_tag="VQT46_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819352.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         6698 a         4437 c         3832 g         6345 t
ORIGIN      
        1 attaaagaaa ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag
       61 ggggtactat ctgtatcctt tttgggaaat tttgaaaata tttttctaat taaattatac
      121 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
      181 accaccaaca tgttgctgca taggctacac ctccaagtat agctccaccc gcagcaccag
      241 ttgctgcacc ttgccatgtt cctgttttaa tgcctagttg aagacctctt gctgctgctc
      301 ctccaacacc tgctttggca aaatctcccc aattgcatcc gccaccttca acgcaagcaa
      361 gcatttcagt atccataaca gaaaattgtg acatcatttt tgtatccatg acaaatactc
      421 cttttttaaa aaactaaaat aaatcagaat agaatcctca taattttact ataagtctta
      481 ccaacttagt cccaatttat caccaaccat acctcctaag catgttaatc cacccccaat
      541 tgcaccaatg tgtgctccaa caaatgcacc agcaagtcca gctactccta aagtggccaa
      601 acctgctcca gttccaccag ttataattcc cgtagtgact cctgtaatca gtgcattttg
      661 acaatcagtg gagctatacc ccccttcaac tttcgcaagc atttcagtat ccataacctc
      721 taactgtgac aacatttttg tattcatgat gaatacctcc tttttatttt caatttgtta
      781 ccaaagtctt aaattcaata aacaaataga ttttttatag tatctttttg attttcttaa
      841 aaaagtatat acgtctacta tcttcttaaa ggtagcagta cctatttttt agtctaagat
      901 ttcaataatc ttgagtatct aaaatatctt aatttcgtta ttctccttgc aataaaaagt
      961 tttactatac tatttattaa cttgcagaaa gcaaaaaata ttagtaaata atagtttata
     1021 gttaagtttt ttattcctac caatccatca actaagtaaa gcatcaacga ttacataaac
     1081 gattgataat ataattaaaa ttttgctaac tatcttattc tcatcattct tagataactt
     1141 tgatattttg taagtaagta aataagacag taaattaata gcgataataa tactatattt
     1201 aagaatcata atcttacaaa gaggacataa ttcctgaacc tacacaaata agtgttgctg
     1261 ctcccccagt tatcggacca gtcgcagcag ctaatagtac tgctccaata caaccaccga
     1321 ttgcagatcc taaattgcct cttcctccac taactatttc gagttcttca ttatccataa
     1381 cagaaaattg ttccatcatt tttgtattca tgacaaatac tccttttttc tttttttatt
     1441 tttgtcttgt tgtaactttg ataagtttag tatatcatcg ttttttaaaa tttttcatcc
     1501 agatcttgaa ttgtcatcga aacgtcttga attagctttt ttatttcaag ccacctctaa
     1561 atgtttaaaa aaaataattt ctaatcactt ttttaccatt caggaagttt taatgactat
     1621 tcaagatttc ataaaatatg aacttagttt tatgacataa tagacctatc cactatatga
     1681 aaagaattgc caatgacttc ttataaacgt acatttgttc ctcaaataga tgcgagagac
     1741 tgtggtgtcg ctgccttagc ctcgattgct aaattctatg gttcagattt ttctctagct
     1801 cacttgagag aacttgcaaa gaccaataaa gaagggacga ctgctcttgg cattgtaaaa
     1861 gccgctgatg aaatgggctt tgaaacaaga cctgttcaag cagataaaac gctctttgac
     1921 atgagtgatg tcccctatcc atttatcgtt cacgttaaca aagaaggaaa actccaacat
     1981 tactatgttg tctatcaaac aaagaaagac tatctgatta ttggtgatcc tgacccttct
     2041 gtaaaaatca ctaaaatgtc aaaagaacgc tttttctatg aatggactgg agtagctatt
     2101 tttctagcta ccaaacccag ctatcaaccc cataaagata aaaagaatgg tctactaagc
     2161 aagcttcctt cctctgattt tcaaacaaaa atctctcatt gcttacattg ttctctcaag
     2221 cttattggtc actattatca atataggtgg ttcttactat ctccaaggaa tcttggatga
     2281 atacattcca aatcagatga aatcaacttt aggaatcatc tcagttggtc tggttatcac
     2341 ctaggttatc acctatatcc tccaacaagt catgagcttc tccagagatt atctcctaac
     2401 cgttctgagc cagagattaa gcattgatgt gattttatcc tatattcgcc atatttttga
     2461 acttcccatg tctttctttg cgacacgtcg tacaggagaa atcatttcac ggttcacaga
     2521 tgctaactct attatagatg ccttggcttc taccattctt tctctttttc tggatgtttc
     2581 tattctgatt cttgtagggg gagtcttgct ggcacaaaac cctaatctct tcctcctttc
     2641 tcttctttcc attcctatat acatgttcat catcttttct tttatgaaac cttttgaaaa
     2701 aatgaaccat gatgtcatgc aaagtaattc tatggttagc tctgccatta tcgaagatat
     2761 caacgggatt gaaactataa agtcgctcac gagtgaagaa aatcgctatc aaaatataga
     2821 cagcgaattt gtagattatt tggaaaaatc ctttaagctc agtaaatatt ctattttaca
     2881 aacgagttta aagcagggaa caaaattagt tctgaatatc cttatcctat ggtttggcgc
     2941 tcaattagtc atgtcgagta aaatttctat cggtcagctg attaccttta acacactttt
     3001 ttcttacttt acaactccta tggaaaatat tatcaacctc caaaccaaac tcccatctgc
     3061 gaaggtcgct aataaccgtt tgaacgaagt ctatctagtc gaatctgaat ttcaagttca
     3121 agaaaaccct gtccattcac attttttgat gggcgatatt gaatttgatg acctttctta
     3181 taagtatggt tttggacgag ataccttaac agatattaat ctcacgatta aacaaggaga
     3241 taaggttagc ctagttggag ttagtggttc tggtaaaaca actttagcca aaatgattgt
     3301 caatttcttt gaaccctaca aagggcatat ttccatcaat catcaggata ttaaaaacat
     3361 tgataaaaaa gtcttgcgcc gtcatattaa ttacctaccc caacaagcct atatctttaa
     3421 tggctctatc ttggaaaatt taaccttggg cggtaatcat atgattagcc aagaagatat
     3481 tctaagagct tgtgaattag ctgaaatccg tcaagacatt gaaagaatgc ctatgggcta
     3541 tcaaactcag ctctctgatg gagctggtct atcaggagga cagaagcaac gaatagccct
     3601 cgctcgtgct cttttaacta aatctcctgt tttaatacta gacgaagcta ctagcggtct
     3661 tgatgtcttg actgagaaaa aagttataga taatcttatg tccctaactg ataaaaccat
     3721 tctctttgta gcccatcgtc tcagtatagc cgaacgaact aaccgtgtca ttgttcttga
     3781 ccaggggaaa atcattgaag ttggtagtca ccaagagtta atgcaggcgc aaggcttcta
     3841 ccatcatctg ttcaataaat aaggagaatg tcatgaatcc taatcttttt agaagcgtcg
     3901 agttttatca gagacgttac cataactatg cgacagtgtt aattatacct ctttcattac
     3961 tgtttacttt catcttgatt ttctcccttg ttgccacaaa agaaattact gttacttccc
     4021 aaggagaaat cgcccctaca agtgtcattg catccattca gtcaaccagt gataatccta
     4081 tccttgctaa tcatttagtg gcaaatcaag tagttgaaaa aggtgactta ctcatcaaat
     4141 actctgaaac aatggatgag agtcagaaaa ctgccttaga aactcaatta caaagacttg
     4201 agaagcaaaa agaaggactt ggaattttga aacaaagttt agaaaaagcg actgatcttt
     4261 tttctggcga ggatgagttt ggctaccata atacctttat gaattttact aaacaatccc
     4321 atgatattga actgggtatc acaaagacta acaccgaagt ttcaaatcaa gctaatcttg
     4381 ccaatagcag ttcatcagcc atcgaacaag aaattacaaa agttcaacaa caaattggag
     4441 aatatcaaga gttgagagat gctatcataa ataacagagc acgcttacca actggcaatc
     4501 cgcaccagtc aattttaaat cgttatctta tagcctctca aggacaaaca caaggaacgg
     4561 cagaggagcc atttttatct caaattaatc aaagtattgc aagtcttgaa tcatctatcg
     4621 caagcctcaa aattcagcaa gctggtatcg gaagtgtagc aacttatgat aatagtttag
     4681 caaccaaaat tgaagtactc cgcactcagt ttttacaaac agcctcacag caacaactaa
     4741 ccgtggagaa tcaattaaca gaattaaaag tacaactaga tcaagcgaca cagcgcttag
     4801 aaaataatac cttaaccgct ccaagtaaag gtatcgttca tctgaacagc gaatttgaag
     4861 gtaaaaatag aattccaact ggtacagaaa ttgctcaaat attccctgtc atcacagata
     4921 caagagaagt actaatcact tactacgtat catctgacta tctcctctta ctagataaag
     4981 gacaaactgt aagattaaaa ctggagaaga ttggaaatca cggcaccacc atcatcggcc
     5041 aacttcagag tattgatcaa actcctacca gaacagagca aggcaatctc tttaaattaa
     5101 ccgctcttgc aaaactatct aacgaggata gtaaactcat ccaatatggc ttacaaggtc
     5161 gcgtcactag tgtaactaca aagaaaacat attttgatta tttcaaagat aaaattttaa
     5221 cacattctga ttaattttca gataacactc tataactatt tattatctta tcaaaaagga
     5281 gaatcataac atggataaga aacaaaacct aacttcattt caagaactaa caactaccga
     5341 actcaaccaa attataggtg gaggatggtg ggaagatttc ttatatagat ttaatataat
     5401 tgaacaaaaa aatacaaaag gatttcatca gccaatacaa ctataaaaaa acaagaccaa
     5461 gagaacgcac tctcggtctt attttttctt cattctatat gtattacagt aagtacctga
     5521 cgaaaaacgt gatcttggca ggtggtattg agactggtat tgggatgact ttccacaatt
     5581 ttcataacgg tatagagacc aactcctctc tcctcccctt tagaacttgc tccaaaggag
     5641 aagatttcag aaatatcgat tccctcttct ttgatggaat tttcaatgat aaaggtctcc
     5701 tgtgctccat tttttaaaaa ggcaattgaa acatgaggtt gacaggcttc tacactagct
     5761 tcaatagcgt tgtcacaaag gatagacaca acggttagaa aatcaagtag actcatcccc
     5821 tctacctgaa tctcctctgg aacttcgaca ttaaagacaa tgttcttatc tctagctttt
     5881 agaaatttcc ctgctaggag acttttgagg gctttatcac gaatattcac caatcgacca
     5941 aggtcatatt tattgtcctg caatttttca ctagaatcct ttaagaccga gtcgtagatc
     6001 tcttttatct gctccatatc ctcctcttca atgcccagac gtaagctagt caagaggttg
     6061 gtgtagtcat ggcgaaaact ccgtacttcc ttataaagct cctctatatg ccgactatac
     6121 cgctccatct ctctgtagcg caagtcctgc tcttggttca gtctctcatg gagtttgtcc
     6181 ttcaaatagg tatccaattt cttgataatc cccataaaaa agagcaggta aaagactagg
     6241 atgagatggc gaacagtcgt tgattgaatc ccctgttcat attcaaagta agacagattt
     6301 tgtatcacca aatagtaagc ccccattatc cagttaatct gagtcaggga cttttgaaaa
     6361 tctttatcga gaatcccctt tctcaagcta gtgaaatcat agtccaacca tttcaaaaaa
     6421 gctagagaaa tgaagaaatt gaaaattatt atacataacc aaataaatga gtagtcatca
     6481 tatacttgcc cttgtcccaa aaatggaagc acaaaatagg aaacacctct ataaaagaga
     6541 ttcactaata tcattggaaa gagaccataa aagagaagga gttttttagg aagttctctt
     6601 aacaataaga aagataagcc tatgccgtac aagggttcca taaaataaga tagataagta
     6661 tttcctacca tatagccaag cattccaaaa acaacggcca acagtatctt aaaaagaaag
     6721 gccttaaaaa tcctctcaaa agtgagacta attccatcta ccttaaagaa tatgacaatt
     6781 tttaatccgt gagtaacaag tgtatacaac aatatccaag caacattcat aaactctcct
     6841 agctcagtgt aagttattaa tagcctcaga cacttccctg accttataac gcgcgattag
     6901 acaacttcca ccattgggaa agaaaagcag tttttctttc ttatctaaat gcaccacatt
     6961 ggcaggattg atgagaaaag agcgatggca ctgcaagaga cgaggctcct gcttgagaac
     7021 ctcctctaga ctcgctgtaa attccagcct gtctgtcttg gtatagagaa taacacgatg
     7081 gggtcttgtg gacgtttcga gatagtaaac ctctttaaaa ggatactgga attgagcaaa
     7141 ttttgattta aagtaaaagc aatcttccgc tagactttta ctgtcttgac cattggcata
     7201 gaggagggct gtctcgatac gagattcaaa ctcctctgcc gaaagggcct tatcaatata
     7261 gtccagagca gacacttggt agcgaaagga caggggcata aactccgagt gagtcgtcac
     7321 aaagacaatc agggcatacg gatcccgatc ccgaatcttt ctagccactt ccagaccctt
     7381 catctcctca tttcgaatct caatatccaa aaagaatagc tgatgggccc ccttctcatg
     7441 cacctctgcc agcagttggt ctggcttgcc aaatacctca aaagagctgg gagtgatatg
     7501 atgttccttc aagagtttct caatcgtcgt ttcaatccta gtctgttggg aaaaatcatc
     7561 ctctaaaaca aatattctca tcttcttact ctccctcttt caaccatttt tgacgaattt
     7621 ctctatagcg acgtctggca tacttgacag cgtattgacc ttcttctccg agaaaaagga
     7681 ttctttcttg aaaatcaatc gattttaatt tatcaagatt aaccaaacaa tttcgatgac
     7741 atctcatcaa ggtttcccca tattggttct caagattact taaattttga agcatattaa
     7801 aactagcttc ttctgtaaca atctgtacgg tatgggcttt agttggatgt gtttggatat
     7861 agtagatatc gtcgacgttt actttataga ctgttttctg cgtctgaata atcatatgtt
     7921 tcattggatt ctcctcctaa gaaaagaata acagaaaagt tctagcccaa gcccacccaa
     7981 tcctaaacag tctttgaaag ctcctaaaag gattattttt ctacaacatc atgatgagct
     8041 tacaactatt ttatcataaa attcactcag cgcaattcaa gacatttcaa tgacaattaa
     8101 agatttgaat aaaaaaaaag aattaaaaat gataaactaa cagtatcaaa acacagttgc
     8161 cagaagtaag actggcaccc agattaaagg aggcattccc atgacagata cagaccccat
     8221 caaaagagct catactttga ttactgactt aaacaaagcc taccaagcat gcaaacaggc
     8281 aagcgctgac gacgtccgct ttcaggagca attaaactct attcttggtt ttttagccaa
     8341 ggctgaaaca gtggataatc gattcttgat tgaactagaa aaattttacc agacttccag
     8401 tcttctcatg ggactcagcg ctcttgatcc agatgctcca actcgcgccg cttggcgggc
     8461 ctatgaccgc ttccactttg accaagtcaa gaccaagtta atactcaatg aaaatcaaag
     8521 agcaaactag gaagctagcc gcaagctgta cttgagtacg gtaaggcgac gctgacgtgg
     8581 tttgaagaga ttttcgaaga gtataagtct ctacggacca accattatcc tgtagtaaca
     8641 aaaaagaagc tgagacagac tgaactcaac ttctttttta gtgtcgtatc agcaatgtta
     8701 gtcctgcatc tgacgtttta cctgataagg caaatacaag actagtaaaa ccaaaccagc
     8761 tcctagtaag gctagaaggg ccagtttttc ttggaaggta atcaacccaa caactaattc
     8821 cacaagtaaa acaaaactgg tcaatcctcg aactacctcc tgtaagcctt tttccttttg
     8881 ccccttgtcc agcggaaaga gttgggtcaa atactggtag tcaaaggcat gatagagggc
     8941 cagcaactgg aagagcaaga ggtagttaaa gagaactacc actgctgtcg caatccaagc
     9001 ttgctcgata aaaacctgcg ccagtacgga aagtaataga agacgaagac tgagagcaaa
     9061 gaggtcgcca tttcgcagat aagaacgcag atagagattt tgccaaatct tcccaggcac
     9121 cttctgaaca gcctttaaga taaagtccag ataggcacga cgcttaacgc tgtttgaaat
     9181 tcccttgacc tgcgtaaaga gggcaaagaa acgaagcaag acttgcttac gcttgctttc
     9241 ttgagaaata acatagtccc agtccagtcc agtttcagta aaaaatttgc tggccttttg
     9301 acgaaagtgg aaatattttc ctacccccaa taaaagcaca tatagcagaa aaactggcaa
     9361 gccataaccc attgctaaaa ataaaggcgc aaataacagc aagaaaaggg tctgtacaaa
     9421 gagccaaaag actagggaaa tgccagtttg acgcttgaga tggagcttga ttgcctcttc
     9481 tccaactaag agaaagagct tgtctggagc ctccatatag gtggcaattc ctccccaaag
     9541 taagagtaaa acagacgtaa ttcctacaaa caaaaggata ggccaatgat tttcaggaaa
     9601 atgttgtaag agttgactgt actggtaggc tagaaagccc aacaggacaa gcaggaacaa
     9661 gacaaagtgg tcattgagca catagcgcag ataacaaaga cactccttac gaaaggcctg
     9721 ctttctcttt aaaaacaagt ctttcataga tcctcctctt tggtcagagc caagtaaata
     9781 tcattcaaac tagcctcagg catatcaaag gcttcacgta gttgcaggag attgcctttg
     9841 gcacgcacct ctcccttgtg aagaatgaca aaggcatcac acatcttttc cgccgaatcc
     9901 agcacgtggg tactcatgag aatagacttg cccttttgct tctccacttc caaaagctga
     9961 atcaaatcag aaatagccag cggatcaaga ccaaggaaag gctcatccac gatgaaaaga
    10021 cttggatcca ccacaaaagc acagataatc atgaccttct gcttcatccc ttttgaaaaa
    10081 tgaacaggga accagtctaa tttctgttcc aaacggaaca tttttaacaa gggctctact
    10141 cgttcgaaag ccactttttg ctcaataccg taagccatag caaccgtttc gatatgctct
    10201 ctgagggtca attcctcata cagactaggc gtctcaggaa tgtagccaat ctgcttgcgg
    10261 tagctagtcg catctccttg cagagtcagg ccattgatat tgatggagcc actataaggt
    10321 gccaacagac cgataatctc attgatcgtc gttgatttcc cagcaccatt gagaccaatc
    10381 aaaccgacca actgcccact ttcaacagta aaggacacat ctttcaaaac aggaacatga
    10441 acatagccac ctgtcaggtt tttaatttct aacatatttt ctccaaatct ggtataatgt
    10501 agctatatta tatcaaaatt cagtacagta gaggtagatt ttatgtcaga ttgcattttt
    10561 tgtaaaatca tcgcagggga aattcctgct tcaaaagtat atgaagatga gcaggtcctt
    10621 gcctttcttg atatctctca agtaacacta ggacacacct tggtcgtgcc aaaagaacac
    10681 tatcgcaatc ttttggagat gaatgctacg agcgccagcc aactctttgc ccaagtacca
    10741 aaagtagctc aaaaagtcat gaaagtcact aaggctgctg gtatgaatat catttccaac
    10801 tgtgaagaag tcgctggtca aacagttttt catactcacg ttcaccttgt gcctcgctac
    10861 agtgctgacg atgacctcaa gattgatttt atcgcccacg aaccagactt tgacaaactt
    10921 gctcaagtcg ctgaaaccat caaaaacgct taaggagttg ctatgaaatt atccaaccta
    10981 ctgctatttg caggagctgc agccggaagt tatctggtta caaaaaatcg ccaaaccatc
    11041 acagatgaag tcttgaatac cactgaccgc gttcaagcta tcaaagacga tgtggatatt
    11101 atccaaaata gcctgcaaat catcgaccag caaaaagaac ttatcaagga ataccaagaa
    11161 gacttgactt acaagtttaa ggtcttggaa aaggatatcc agactagact agctgtgata
    11221 aaagaaatgc agggaactga agataagtaa aaagagcccc ccggctcttt tttaaaacgt
    11281 aaacaagtta tagtgaattg aatttagaat agcacatcat agtttctaaa gcattgttag
    11341 agattacttt aaaatcctct tatcaatttg ttcatattct atttcaatct actatatata
    11401 tcccatcaac tatgcatcat aatttaggta actcatactc aataaaaatc aaaaagcaaa
    11461 ctagaaagct aggcacagac tgctcaaaac accgttttaa ggttgtggat agaactgacg
    11521 aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
    11581 cccatgacaa gccgacgctg acgtggtttg aagaaatttt tgaagagtat cattcaccat
    11641 ttcacaacta aatcgaagac tttctgccgt aatgaaaaca cctgaaacag cttggtttca
    11701 gctgtccgga aactttaaga cttaggttca aagtttaggt atggaacttc gaaggaggtc
    11761 gctaccgtcc gtcattactt aggaaagtct taaaaaatct ataaagtaaa aagagcccga
    11821 cagctctttt tgtttatact caatgaaaat caaaaagcaa actaggaaac tagccacggg
    11881 ctgctcaaaa cactgttttg aggttgtaga tacgactcac atatatacgg caagccgacg
    11941 ctgacgtggt ttgaagagat tttcgacgct gacgtggttt gaagagattt tcaaagagta
    12001 ttattctcca tcaaaggcat ctttaatatg gtcaaagaag ccttttttct ttggatttac
    12061 tttcaagtca ccagcagccg cgaattcttt caaggctact ttttggcggt cgttcaagcc
    12121 tgtcggtgtt acgacattaa cagtaacgta ttggtcacca actgcaccgc cacgaaggct
    12181 cggtgccccc ttactacgta ggcggaattt cttaccagtc tgagttccct ctggaataac
    12241 caattcaaca tcaccgtgaa cagttggaat atctactgta tcaccaagag ccgcttggac
    12301 aaagttgagg ttgagattgt agaagatagt cgttccttca cgttcaaact tgtcgctagc
    12361 ttctacagaa actactacat acaagtcccc ataaggtcca ccgttaaagc ctgcttcgcc
    12421 ttgaccagcg aggcgaattt gttgacctgt ttccacacca gcagggattt tcacatgtac
    12481 gctatgagct tgtttctcat gacctgttcc atgacaggtt gtacatggat atttgatttc
    12541 ttttcctcga ccgtgacaga catcacaggt tacttggcga cgcatcatac caagaggagt
    12601 ctgcgtatcg acgttaatga caccagcgcc atgacagcgt ccacaagtga ctggacttgt
    12661 ccctggctta gcaccagagc cattacatgt acgacagcca gcttcacgat gatacttaac
    12721 ttccttctca gttccgaaga tagcttcttc aaaggtcaaa ttgacacgat actggagatc
    12781 atctccttgg cgaggagcgt ttggattgcg cgaagaaccg cctccgccga agaaacttga
    12841 aaaaatatcc tcaaaaccac cgaagccacc tgccccattg aaaccaccga aaccaccagc
    12901 tccaccaaaa ccaccattgg cgcctgcagc accatactgg tcataggcag cacgtttttg
    12961 gtcgtcactc aaagtctcat aggcttcttg aacttccttg tacttgtcct cagcaccagg
    13021 ctccttgttg atatctgggt gatatttttt ggaaagctta cgataagcct ttttgatctc
    13081 gtctgccgaa gcgttttttg acacccccag acgatcataa aattcagtat tgttcataca
    13141 agataccaag accgtaaaat tcgactgaaa aataggaaat ctgacgctgg agcgacgctc
    13201 ctagacagat ttctcttttt tccgagaatt taggtcgggt tcaattcctt tcttttatat
    13261 tgatgagata atactccagc cactcggccc tatccctttt taccgaaaaa cagaggctga
    13321 gttgcaacct ctgtggttag attattcatt tgaaataaaa atggttgtat tatctctagt
    13381 agtaatcttc aaagaccttt tagctaaatc aaactcaaat ttattatagt gtgggtcttg
    13441 tgttttatat aggtgtaact cctgacatat atgatccgaa aagtaaatca taacatcttt
    13501 aaacacagaa gtgtggtcat atttactctt accaacagct acttctgtaa attctttata
    13561 aatgacattt ccatttcttt ccacagtcac cagcatttct gttggattat aatccaaatt
    13621 aaataattct tcaaaaaact ttatcttttc atgataatct gcaatgtcag aaagattatt
    13681 tttattaaca ctcataacac tagcccctta tttttcagta aactctccgt ctacgacgtc
    13741 atcgcctgcg tttcctgttg cttgtgcgcc ttctgctcct tcttgagctt gttgcgctgc
    13801 tgcagcttgt tcgtagagtt taacagcaag tccttgagct ttttcgttca atgcttcaag
    13861 ttttgctttc atgtcgtcca agttgttgtc ttcttgagct ttcttaaggt catcaagggc
    13921 agcttgggca gcgtcacgtt ctgcgtcgaa gcctttacct tcagtttcct tgattgtctt
    13981 ttcagtcgca aagattgctt ggtctacttc attacgaagg tctacttctt ctttacgttt
    14041 cttatcggct tcagcgtttg cttctgcatc tttcatcatg cggtcgattt cttcgtcagt
    14101 caaacctgag ttcgattgga tgacaatagt ttgttctttt tgagttccaa ggtctttggc
    14161 cttaacagac acgataccgt tcttgtcgat gtcaaatgtt acttcgattt gaggaattcc
    14221 acgaggtgca gctgggatat cagtcaattg gaagcgtcca agagtcttgt tatctgctgc
    14281 cattgggcgt tcaccttgaa gaacgtggat atcaacggct ggttggttgt ctgctgctgt
    14341 tgagaagact tgtgatttag atgttgggat tgtagtgttg cgatcgataa gttttgtaaa
    14401 tactccaccc attgtttcga taccaagtga caatggcgtt acatcaagaa ggacaacgtc
    14461 cttgacatca ccagtaatca caccaccttg gatagccgca cccatagcaa ctacttcatc
    14521 agggtttact gatttgtttg gttctttacc agtttcagct ttaacagctt caacaacggc
    14581 agggatacga gttgaaccac caacaaggat aacttcgtcg atttctgaca agctcaaacc
    14641 tgcatctgaa agggcttgac gaactggaac ttttgtacgt tcaacaaggt cacgagtcaa
    14701 atcgtcaaat ttcgcacgag tcaaagtcat ttccaagtga agaggtccag cctcacctgc
    14761 agtgataaat ggcaagctga tttgtgttga agttacacca gaaaggtctt tcttcgcttt
    14821 ttcagccgca tctttcaaac gttgcattgc catcttgtca gtagacaagt cgataccgtt
    14881 ttctttcttg aattctgcta ccaagtggtc aatgattttt tggtcaaagt cgtcaccacc
    14941 aagtttgttg tcccctgcag ttgacaatac gtcgaagaca ccgtcaccca attcaaggat
    15001 agagacgtcg aatgtaccac caccaaggtc aaataccaag attttttctt ctttgtcagt
    15061 cttgtccaaa ccataagcaa gagctgctgc agttggttcg ttaacaatac gttctacttc
    15121 aagaccagca attttaccag cgtcttttgt tgcttgacgt tgagcgtcgt tgaagtaagc
    15181 cggaactgtg ataacagctt tggttacttt ctcaccaagg tagtcttcag cgtagccttt
    15241 caagtattga aggatcatag ctgagatttc ttgtggagtg tattcttttc catttgcaga
    15301 aactttttca gaagttccca tcttagattt gatagagata actgtatctg ggtttgtaac
    15361 tgcttgacgt tttgcagcat caccaacgat gatttctccg tttttgaatg agactacaga
    15421 tggagttgtg cggtttcctt ctgggtttgc gatgattttg ctttcagttc cttcaagaac
    15481 tgcaactgct gagtttgttg tacctaagtc aataccgata attttagaca tgtgtttttc
    15541 tccttgttag ttaattttct atttttcttt ttgatactct tcttaagtgg cgacgccgtc
    15601 agagcttgac ttcgtcaatc tctttgacta aactttgagc ctaaggtctc aaaatttgcg
    15661 caaatagcac cacggcgaag agtatcgtct ttggttcgct tcgctcacta ttacaaagcc
    15721 aaacatattt tatctttctt catagtttat tgtcgtttcg gacaagtttt ctattatgta
    15781 aattgcgaca cgaggagtcg aaatcgattt tatttcgacg acgagttagt aaggaagcta
    15841 ggcaaacgtc atagcgattg ccgttttctg acgagttgct ttagctaccg tcagaattgc
    15901 cgaatcgaac acgccctaag ctctgagtaa aaaagataga ttttcttgtg ttcatcgaac
    15961 acttcgtcaa tctcctattt ttactgcgag ctttttacga gctttgtatc ttagttatac
    16021 accactacca ttgctgggcg taggatgcgg tcatggagtt tgtagccttt ttgaaagact
    16081 tgggcgatgg tatctactgg gtgttcatcg tctgctggga gagtttggat ggccatatgg
    16141 tagttatggt caaattcgcc atctgctgcg atttcttcaa ttccttcttc tttcaaagcg
    16201 tgaatcaagc tttcttgcac catccccaag cccttcttca catcatctgt caaaccttca
    16261 actgcaagtg cacgctcaag gttgtcaaga gatggtaaga ttgcttttgc caagtcctgg
    16321 ctacgataac gttgcaagtt ttgacgttct tcattggcac ggcgttggat attttgcatt
    16381 tctgcatgag cgcgaagata tttgttttcg aactcatctg cacgttcatt tgccaagtcc
    16441 aactcagact tttcaggagt tgtttcttca gctgtttcca caacttcctc ttcttgaact
    16501 tcttctactt cttcattttt tatatcttgg gccatgttcg cctcctttaa tgatttcaat
    16561 cttaatgtac ttcgtaatga ttactgctga ggtagcggta aaaatctgtc aacttcatgg
    16621 tcaaaacacg gttgaccaca ttgacttgat tgattagctg ttggtaatcc agattaactg
    16681 gaccgataat ggctagaatt ccaactcccc gataaggaat gaggaactta ctactaatca
    16741 ccgctaggtc agctaaacag gactcttgac cgtctgcaac acgaacattt tgcatctgat
    16801 cctcacgcaa cccctcacga atctccaagg ccaccttttg cggttggtca aagaactgat
    16861 aggcttctag attggcaaaa ttcaagagat tgaccttgcc cgccatcaca atgttttcgt
    16921 tgaacatttc cttaaagatg tgttcaaaga gatcgatgac attatccgtt gttgtaaagt
    16981 aacgctggat aatctgcgga atctccgtcc gaatcttgta gtgaatatct aaaacggtgt
    17041 gaccgaggaa acgttcctga atgatgctct tcagtttcag caaatcctcc tgcaagaagt
    17101 tccttggaat cagaaactga ctagtaaccg ttcgcgactc gtctagggta aataccgcca
    17161 aggctgtatg ttgccccaaa acaacgatat caaaggctgt caaacgttgc ctgctcggct
    17221 caacatccag tgccactacc gtacagccac tcaggcctgt tagcaagtta gcagcctctt
    17281 gcagaatatc ctccaatttg aagaattcct gatcaaaggc tttgacaatc tcatatacct
    17341 cattttcagc cagccggtga aaatccagtg agtgtttcac atagtactga aaaccagcaa
    17401 cacttggcat ccgaccgctt gaagtatgag ccttctcaag caacccttgt ttttctagtt
    17461 ccgccatgtc attacgaatg gttgcactgc tagagttaat agactcttgc aaggcttttg
    17521 atccgacagg ttcgtgcgtt ttggtaaaga tgtcaataat cagatttaaa atatcctgct
    17581 gacgctctgt aaccatctca tcactcctct ctgtctgatc aattagcact caatgcatcc
    17641 aagtgctaac ttatgattct attatacacc cttaaaagag aatgtcaaga caaaaactca
    17701 aaaaattagc actcttttat caagagtgct aaaaatcaat ctgaagacct agaaccttgc
    17761 tattcatcta ctcggtattt cctttttagt ctgaaataac catgaattag ataagaaatc
    17821 agaaaagcat ataaaacaaa aataagaaag aaagacatag aaagatcctc tctaaacaaa
    17881 ctcgtacaaa caacaagacc acctaagaaa gtagttgtac aggaacgaag tctagatcgc
    17941 ataacttccc atttgagccc cttactcata tagacttgat cctctggaag taaatcagaa
    18001 gacgatttac gaagaatcga acaagaacct gctcctatca attcccaacc tctatctcta
    18061 aaatcttgca gttcatgctt atatttttta agaaatctag aatcatagat acggtagatg
    18121 acatcgtctg gttgacattg gtcaaaatag aacaaaccaa aacgactcgt tctatacctc
    18181 caacctttca aatgcatctc atgtaaatat tcttcttcct tgtccaaatc aacaatggtg
    18241 aaaatccgaa attctactct gctattcatt gtcttacccc aaaattagaa aacatgcctg
    18301 gcgttattta ttagataatt ctttccactt ttgactcaat ctccaaaaaa tataagaaat
    18361 ctgaatcgca aaaactatca ataaaaccca atctattatg aaaatcaaaa acactttcca
    18421 actgaaagaa ctacctccag tgacaaactt tgagcaaaac ggtagtagag ctaaaaagag
    18481 aagtaaaata ggaagcatcc gcattgttaa aatccgtttg gcataaaaaa atctttattt
    18541 aaactaaaat attatagcaa aatttacgcc agtttttgaa cggctgatgt agatatttta
    18601 tactttcaaa atgtttaaat gtgattattt atttttgaaa aatagctcac cagcccgact
    18661 gaaagtgctt atagaatgat aataagtcgc ctgccgaaaa cagcggaaaa tagcggtgtt
    18721 atgcggagat aatctgacgc gatgcgaaag tatattgcat acttattttc aacaatttag
    18781 cagagtattt ttataagtgt gatataatag aagtataatt tgttctgata gtttatttta
    18841 tggagaagta gatttttaga atgcggaggg ttcaatatgg ttgagtttat aaagtctaag
    18901 aaagaaatga gtgaggagga tattaaagca aatttcatca ctcctgctat tgtatccaaa
    18961 ggatggaaaa atggtgagca tatcgcttac gaagaatact tcactgatgg tcgaattgag
    19021 gttagaggag ataaggctcg tcgtaaagaa ggaaaaaaat cagactattc actgtattac
    19081 caatttggaa ctcgaattgc aattgttgag gcaaaggata ataaacacag cgttcgagca
    19141 ggattacaac aagctattga atatggagag attttagatg ttccatttgt ttattcttcg
    19201 aatggtgatg gctttattga acacgaccgt atcacgagag aagaacgtga gctggagtta
    19261 gacgaattcc ctactcgtga agaattattt tctcgtatga cgaaggaaaa aggattgacg
    19321 tacgaaatta cagaagctat ctcaactcca tactatacag acgccttctc aatgaaaacg
    19381 ccacgctatt atcagcaaat agctatcaac cgtactattg aaacagttgc cagaggacaa
    19441 aaacgagtaa tgtttgtgat ggcaacagga acagggaaaa cgttcatggc ttttcaaatt
    19501 attcatcgcc ttcgaaaagc tggtttggct aaacgagttt tattcttagc agatagaaac
    19561 atcttagtag accaaacgat ggctgaagac tttaagccat tcgaaaaggt aatgacgaaa
    19621 attacaccaa aacttttgac tgctcctgaa aaattaaatt ctttcgaaat ttatctaggg
    19681 ctttatcagc aactaactgg tgaagatgga actgaaacac attatcaaaa atttgacaaa
    19741 gacttctttg atttaatcgt aattgatgaa gcgcaccgtg gttcagctaa ggaaaacagt
    19801 aactggcgta aggtaattga ttatttcagt tctgcgacac agattgggat gaccgctact
    19861 cctaaagaaa ccaagaatgc ttccaatacg gaatactttg gtaagccaat ctatacttat
    19921 agtttaaaac agggaatcga ggatggtttt ttggctccat atcgtgttat gagggttaat
    19981 ttagatgtgg atgtggatgg ttatcgtcca gaaactggaa aagttgatgc taacggacaa
    20041 ttaatagaag ataggtacta cggcaggaaa gattttgata aaaccattgt cattgatgat
    20101 agaacgcaaa gagttgccaa gtttgtttct gattatatga agcaaaacaa tgcacgattt
    20161 gataaaacaa ttgttttttg tgttgatatt gaccatgccg agcgaatgcg tgctgcactt
    20221 gtaaaagaga atctagactt agtccaagaa gactatcgtt atgtcatgca agtaactggt
    20281 gacaacgctg aaggaaaagc tcaactggat aactttatgg atgtcaattc taattttccc
    20341 gctattgtaa caacgtctaa attattaacg acaggagtta atgctaaaac atgtcgtttg
    20401 attgttttag actctaatat ccaatccatg actgaattta aacaaattat tggtcgtggc
    20461 acacgtcttt atcctcaaaa ggggaaagaa ttttttacga ttattgattt tcgaaatgtt
    20521 accaatttgt ttgctgaccc tgattttgat ggtgagccag tgaaggtgct ggaaacaggt
    20581 gcgaaaacag tcagtggttc tacgcctggt ttcgtaggtg aggaaggtga cccagtagaa
    20641 aaatatatcg ttacagacaa gcaggttacc attcttaatt ctactgttca agtattggat
    20701 gaaaacggga aactgattac cgaaagcctg accgactaca ctcgaaagaa tatcttaggt
    20761 agctacgcca ctttgaacga ttttatcaca gtttggcata cggcagataa gaaacattat
    20821 gggaagtttg ctgatggaag cactcaagaa attgatgttc cttatgatat tcctgatact
    20881 tgggagtggg tgaggttttc tacattggtt gaaattgtca gaggtggctc tccacgacca
    20941 atcaaagatt atcttacttc tgaagtagat ggaataaatt ggataaaaat aggtgatact
    21001 gaaaagggtg aaaagtatat aaataatgtt aaagaaaaaa tcaaaaaatc agggcttaac
    21061 aaaactagat ttgtaaaaaa aggtacattt ttgttaacta attctatgag ttttggtaga
    21121 ccttatattt tgaatgttga tggtgcaata cacgatggat ggttggctat ttcgaactat
    21181 gaaaactcat taaataaaga ttacctattc tatattcttt catcaaatgt agtttattct
    21241 caatttctat ctctaattag tggagctgtt gtgaaaaact tgaatagtga taaagttgct
    21301 tctattctta tc
//
LOCUS       DAVAZV010000038        20904 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVAZV010000038 DAVAZV010000000
VERSION     DAVAZV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20904)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20904)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20904
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.038"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQT46_001371"
     CDS             <1..128
                     /locus_tag="VQT46_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2371393.1"
                     /translation="FRSLENLEQAIVDYIDYYNNKRIKVKLKELSPVQYRTKSFG"
     gene            complement(176..2719)
                     /locus_tag="VQT46_001372"
     CDS             complement(176..2719)
                     /locus_tag="VQT46_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET2371394.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQKKVD
                     ILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTKTFT
                     EAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQAQT
                     GFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(2781..4403)
                     /locus_tag="VQT46_001373"
     CDS             complement(2781..4403)
                     /locus_tag="VQT46_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2371395.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            4609..5634
                     /gene="trpS"
                     /locus_tag="VQT46_001374"
     CDS             4609..5634
                     /gene="trpS"
                     /locus_tag="VQT46_001374"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET2371396.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            5787..7265
                     /gene="guaB"
                     /locus_tag="VQT46_001375"
     CDS             5787..7265
                     /gene="guaB"
                     /locus_tag="VQT46_001375"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET2371397.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQT46_001376"
     CDS             complement(7316..8413)
                     /gene="recF"
                     /locus_tag="VQT46_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET2371398.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQT46_001377"
     CDS             complement(8416..8784)
                     /gene="yaaA"
                     /locus_tag="VQT46_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET2371399.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKIDIPDMNIDILLTQSTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            8943..10193
                     /locus_tag="VQT46_001378"
     CDS             8943..10193
                     /locus_tag="VQT46_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2371400.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSYLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHCPSKYGDEKHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSQLDLFSGFLRMYAGIDRENRNQARKMMNNQLLDL
                     KKGYFTELELEQTKEMIRRSLLLSQDNQSSLIERAYQNALLGKSSADFKSWIAKLEQV
                     DKDAICRAANNVKLQAIYFMEGIE"
     gene            10190..11473
                     /locus_tag="VQT46_001379"
     CDS             10190..11473
                     /locus_tag="VQT46_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET2371401.1"
                     /translation="MTKVVFEEKYYPAVKEMVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTLVTEVDGDVKQYPAGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELITSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            11515..12336
                     /locus_tag="VQT46_001380"
     CDS             11515..12336
                     /locus_tag="VQT46_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2371402.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            12347..12892
                     /gene="pgsA"
                     /locus_tag="VQT46_001381"
     CDS             12347..12892
                     /gene="pgsA"
                     /locus_tag="VQT46_001381"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET2371403.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            12889..13716
                     /locus_tag="VQT46_001382"
     CDS             12889..13716
                     /locus_tag="VQT46_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2371404.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            13701..14540
                     /locus_tag="VQT46_001383"
     CDS             13701..14540
                     /locus_tag="VQT46_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET2371405.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            14533..15327
                     /locus_tag="VQT46_001384"
     CDS             14533..15327
                     /locus_tag="VQT46_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2371406.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            15386..16204
                     /gene="mreC"
                     /locus_tag="VQT46_001385"
     CDS             15386..16204
                     /gene="mreC"
                     /locus_tag="VQT46_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET2371407.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKVSQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            16204..16698
                     /gene="mreD"
                     /locus_tag="VQT46_001386"
     CDS             16204..16698
                     /gene="mreD"
                     /locus_tag="VQT46_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET2371408.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            16792..17970
                     /locus_tag="VQT46_001387"
     CDS             16792..17970
                     /locus_tag="VQT46_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET2371409.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            18194..18973
                     /gene="rpsB"
                     /locus_tag="VQT46_001388"
     CDS             18194..18973
                     /gene="rpsB"
                     /locus_tag="VQT46_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET2371410.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            19052..20092
                     /locus_tag="VQT46_001389"
     CDS             19052..20092
                     /locus_tag="VQT46_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET2371411.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            20339..20680
                     /gene="tnpB"
                     /locus_tag="VQT46_001390"
                     /pseudo
     CDS             20339..20680
                     /gene="tnpB"
                     /locus_tag="VQT46_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
BASE COUNT         6652 a         3357 c         4299 g         6596 t
ORIGIN      
        1 gctttagatc tttagaaaac cttgaacaag ctattgtgga ctacattgat tactacaaca
       61 acaaacgaat taaggtaaaa ctaaaagaac ttagccctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actttttggg gtcagtacat taactggtcg attttttatg
      181 ccttagatga ctttcgtctg tgattataga ttccaaatag taagagagaa gtaaaggaac
      241 agattgctcc agtaataaaa ccattgggaa tgaaggaaag tgtaatagtt cctttcccct
      301 tgggaatgtc aactttcata aatccagttt gagcttgttt aatttctatt ttcttaccat
      361 cttggtaggc agaccaacct ttgtcataag gaatggtgaa gaaaatagat gtatcttgtt
      421 ggacatcata tgtagcaaaa accttgtttt tagaagttga tactgtgaca ggttgttctt
      481 taattttttg aattgcctcg gtgaaagttt tggtatctaa acgatagaag gtaggagatt
      541 caaatgatac ttgtgaattt ccagggaaac taacattgat attgaaagtt tttttctctt
      601 tagtatatcc tagattaaag aaggagaaga cattatcagt tgtaaaagtc tttttttcac
      661 catttacaag gatgtcaacc ttcttttgtt tatcgttaga aaagtgaagg tttatgaaag
      721 agagataaac ttggctgttt tctggaactt caatttgata ctggattgct gcatcttcat
      781 ttgaagaact tgtgacacta atcaaatcat tagtattttc tgttttttca taaggtattg
      841 gagaaaaata atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca
      901 aggtatgttc attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa
      961 gagagtattg attttcatat agggtaagat tatctttttg atagatatct ttaaagccat
     1021 acttatcaat aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa
     1081 tactattatt tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat
     1141 ctaaagtaga gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt
     1201 tgaatttcat actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat
     1261 ttccaatata tgttgagaaa gattccatag ctgggatatc tcgactataa gcacttcgag
     1321 aagcaaatcc ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt
     1381 caaccagtat aaataaagag attagaatgg caaatagatt cacagatata aactttttga
     1441 taactgcaag gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca
     1501 aatctgttaa aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta
     1561 caagaaaaag cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt
     1621 ctgctgctgt gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt
     1681 ttggagtatg catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta
     1741 gaaatgcaaa gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa
     1801 aaaataaaat ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat
     1861 actttgttgt gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac
     1921 tttcagtttg aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata
     1981 gagtgggaag agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat
     2041 caagaacaga tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa
     2101 taagaaacaa tactgtcata tatccaaaat aataattttg aataaataag attgacagac
     2161 ttgtaaagta caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta
     2221 aaggaatcaa gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac
     2281 tcatcagagc ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca
     2341 atttattcaa actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca
     2401 gatagacagc atctggcata ttcgttagat caaaaaagta aactagaggc gcgagaaaac
     2461 tacccaagta ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt
     2521 aaaacagact actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt
     2581 gatgaaagcc atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata
     2641 gatatactcc agacataatc actacaggaa tgatgaaaga aataaaatag gttcgatatg
     2701 tttttaaaaa tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca
     2761 actgagtttt gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct
     2821 gcattttcta ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat
     2881 aagacaatga tatggttagc caaagtttga ataaactcgt ggtcatggct ggcaaagatg
     2941 attgattctt taaagttttt cagtccatca ttcaagcttg agatagattc caagtccaag
     3001 tgatttgttg gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc
     3061 atgacacgaa ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca
     3121 gagaagagca tacggccgag gaaaccacgt aggaaagtat tgtcatcttc ttctttactt
     3181 gcgaattgac gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct
     3241 tttggtaggt aagattgact agttgtaact ccccacttga cagttccttc atagtcaata
     3301 tctcccatga ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct
     3361 gtcttatcat ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc
     3421 tttacagtta gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag
     3481 ttgataaatg gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc
     3541 attttcttac gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg
     3601 aattcttgca attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta
     3661 gcagcaagct cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt
     3721 ccaaagtcaa ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat
     3781 actacgataa ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg
     3841 atatccaaac cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct
     3901 ttggcgagga gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt
     3961 aattcttctg gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa
     4021 cctccaagtt cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag
     4081 aaatcttcct tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt
     4141 cccatgataa cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga
     4201 acagagagac gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca
     4261 gctaaaattt ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta
     4321 tttccttctg taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt
     4381 gaaacatcag atactgtaag caatgttttt ctcctatatg tgtaatatat ttattctact
     4441 agaaaataca gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt
     4501 atcctttaca caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt
     4561 cattaaaaaa atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc
     4621 attattttaa caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt
     4681 ctcaaaaatc gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct
     4741 gaccaacaag ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga
     4801 aatgtggctt tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt
     4861 caaagccaga ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta
     4921 gcacgtttgg agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa
     4981 agcattccga caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc
     5041 aaggctaatt atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa
     5101 attgttcgtt cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt
     5161 tatccagaaa atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct
     5221 aaatcactaa ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta
     5281 atgagtatgt atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga
     5341 aatatggttt tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct
     5401 gatatgaaag aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta
     5461 cttgaaatat tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag
     5521 gatatgggag aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg
     5581 ggtcaaaccc tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat
     5641 tttacaagaa actatcattt ctatctcgaa gaaaagatag tttttttatt tacccctgta
     5701 acatttgaca aatttttata gaatggtatg atagatacaa tataaaaaga gtcaagctca
     5761 aaaagaaaga aaagaggaaa cttcgaatgt ctaattggga cactaaattt ttgaaaaaag
     5821 gttttacctt tgatgatgta ttgcttattc cagctgaaag tcatgtgttg cctaacgatg
     5881 cagatttaac aactaaattg gcagataatt tgactttaaa tatcccaatt attaccgctg
     5941 ccatggacac agttacagag agtcaaatgg ccattgctat tgctcgtgca ggcggtctcg
     6001 gagttatcca taaaaacatg tcaattgctc aacaagcaga cgaggttcgt aaggtaaaac
     6061 gttctgaaaa tggagttatt attgatccgt tcttcttgac gcctgaacat acaattgctg
     6121 aagcagatga gcttatgggt cgttaccgca tcagtggtgt tccagttgtt gaaacacttg
     6181 aaaatcgtaa attggttggt attttgacaa accgagatct tcgttttatt tcagattata
     6241 atcaaccaat ttcaaaccat atgactagtg aaaatcttgt tactgctcct gtgggtacgg
     6301 atcttgcaac ggctgagagt attcttcaag agcatcgtat tgaaaaactt ccgttggtcg
     6361 atgaagaagg cagtctttct ggtttgatca ctatcaaaga tattgaaaaa gttattgagt
     6421 ttccaaatgc ggctaaagat gagtttggtc gtcttctagt tgcaggtgca gtaggtgtta
     6481 cttcagatac atttgaacgt gcagaggctc tttttgaggc aggagcggat gcgattgtta
     6541 ttgatactgc acatggtcat tctgcaggtg tcttgcgtaa aattgccgag attcgtgctc
     6601 atttcccaga tcggactttg attgctggaa atattgctac tgctgaaggt gcacgtgccc
     6661 tttatgaagc gggtgtagac gttgttaagg ttggtattgg accaggttct atctgtacta
     6721 ctcgtgtgat tgctggtgtt ggtgttccgc aagtaacagc tatctacgat gctgcagctg
     6781 ttgcgcgcga atatggtaaa acgattattg ctgacggtgg gatcaagtat tctggagata
     6841 ttgtaaaagc acttgctgca ggtggaaatg ctgttatgct tggatctatg tttgctggaa
     6901 ctgatgaagc tccaggcgaa actgaaatct tccaaggacg taaattcaag acttaccgtg
     6961 gtatgggatc aattgctgct atgaagaaag gttcaagcga ccgttatttc caaggttctg
     7021 tcaatgaagc aaacaagctt gttccagaag gaattgaagg tcgtgttgct tataaaggag
     7081 cggcagctga tattgttttc caaatgattg gtggtattcg ctctggtatg ggttactgtg
     7141 gtgcagctaa ccttaaagaa ctacacgata atgctcaatt tattgaaatg tctggtgctg
     7201 gtttgaaaga aagccatcct catgatgtgc aaattactaa tgaggcacca aattattcta
     7261 tgtaaaaaac aatgaaaaga actccagtga aaacaggagt tcttttacaa tgttgtcaat
     7321 ttccatttac agcagcttta ccatcctgaa tagtgaagat acttagattt tctggcagat
     7381 tttgaagatg gtctaagctt gttgttgtga taaaggtttg gattgattga gaaatcgttt
     7441 ctaataattt taactgtcta gtgttgtcaa gttcactcat cacatcgtca agcagtaata
     7501 taggagattc tgtggtaatg ctttccatta attcgatttc tgctaatttt atcgagagga
     7561 cgagactacg atgttgacct tggcttccga aactagcatc catcccattt atataaaaag
     7621 aaatgtcatc tcgatgagga ccgacaccag tattcttttt aaataaatct ctggatctac
     7681 ttttttctaa agcaattttg aaagattcgg ataagttttg tttgtcagtt atattgacag
     7741 aagattgata ggatattgac aactcttcga tctgattaga gagttcaaaa tgtttcttac
     7801 gcccaaatga ttctagtttt tttatgaaat ctaagcggtg attcattaca cgacatccat
     7861 aatcaactag ctgatcatct aacacagaaa ggaatgtttc atctattttt tgagctgatt
     7921 ttaggtaagt gtttctttgc tttaggatgt ggttataatt ggttaagtca gataaataga
     7981 ttggcttaat ttgcccaagt tccatatcaa tgaattttcg tcgaatcgaa ggtgctcctt
     8041 taattagttg taaatcttca ggagcaaata agacaacatt catgtgtcct acataatctg
     8101 aaaggcgtgc ctgttttaag tgattaactt ttgttacacg gcctttttgt gttagttcga
     8161 tttctagggg aatggatcca gtttttttct gaacgagacc tgaaagatga agttgttcct
     8221 catcaaaatg aatgagattt ttatctgttc gagttcgatg actacgcgtt aaggctaaaa
     8281 aatagatagc ctctaacatg tttgtttttc cttgtgcatt acgtcccaaa aagacattca
     8341 atttaggatt aaagtctatt ttcgtttctt tgtaattacg aaaagtcttg agagatagat
     8401 gttgtagcca catgattatc taccagggaa tcgtggagct tgttggcttt taggtgatga
     8461 agcaggtttc gatttgtctt ttttaactcc cttattcatc tttttgacaa gtttagcgat
     8521 ccgttctttt tcaactttat cagcttggta ttcatcttgt tcttcagaag tagattgtgt
     8581 caacaagatg tcaatgttca tgtcagggat gtcaatttta tcgccaatac gaagtttttt
     8641 accacgacga ctctctaatt ccctattaaa gtaaacagaa tgttcagaga gaaatgattt
     8701 aatagctcct ccgctatgtg taattccaag ttctttgagt agtgcttgga gggtaataaa
     8761 ttcttcaaat aatttgtatt ccataattca cctcaatctt tggtattata ccatattttc
     8821 ctaaaaatag tgagagatac agcgagaaat gtaagcgatt tttatttcaa aagtgttaca
     8881 gggaacaaga aaatttcagg ttttcgtgat ataatagaag tctgtatata aggagataaa
     8941 tcatggagtt agtgcatgga atttcaacac attttatcca atcaaaaaag tttaaaacaa
     9001 acaaaattac cgtgcgtttt accgctccat tatcccttga tacgattgca ggtcacatgt
     9061 tgagtgcaag tatgctagag actgctaatc agatgtaccc cacttctcaa gatttgagga
     9121 gacacttggc cagtctatac ggtacagata tgtcaaccaa ttgtttcaga agagggcaaa
     9181 gccacattat agaattgaca tttacctatg ttcgtgatga gtttttaagt aggaaaaacg
     9241 tgctaacttc tcagattttg gaacttgtaa aagaaactct tttttcaccc gtagtagttg
     9301 ataatgggtt tgatccggcc ttatttgaaa ttgagaaaaa acaattgcta gcaagtttag
     9361 cagctgatat ggatgattct ttttattttg cacataaaga attggataaa ttgttttttc
     9421 atgatgaacg tcttcaattg gaatatagtt atttacgaaa tcgtatttta gctgaaactc
     9481 cacaaagttc ttattcttgt ttccaagaat ttttagccaa tgatcgaata gatttctttt
     9541 tcctaggtga ttttaatgag gttgaaattc aaaatgtatt agaatcattt ggctttaaag
     9601 gtcgaaaagg agatgtgaag gttcagtatt gtcaacctta ttctaatatc cttcaggaag
     9661 gtatggttcg gaaaaatgtg ggacaatcca ttttggaatt aggttatcat tgcccttcta
     9721 aatatggtga tgagaaacat ttacccatga ttgtaatgaa tggtttactt ggtggatttg
     9781 ctcactctaa actttttaca aatgtccgtg aaaatgctgg attagcttat actatttcaa
     9841 gtcagctcga tttatttagt ggattcttga ggatgtatgc tggtattgac cgagaaaatc
     9901 gtaaccaggc tcgtaaaatg atgaataatc aactgcttga tttaaaaaaa ggttatttta
     9961 cagagcttga gttagagcag accaaggaaa tgattcgtcg gtctttgtta ctttctcaag
    10021 ataaccaatc ttcattgatt gaacgtgctt atcaaaatgc cttacttgga aaatcttcag
    10081 cagattttaa aagttggatt gcaaaactcg agcaagttga caaagatgct atttgtagag
    10141 cagctaacaa tgtgaaacta caagcgattt actttatgga aggaatagaa tgacaaaggt
    10201 tgtttttgaa gaaaaatact atccagctgt aaaagaaatg gtttatcgaa ctcgtttggc
    10261 aaatggattg acagtagctc ttttgcctaa aaaggaattt aaagaggttt acgggagtgt
    10321 aactgtacag tttggttcgg tagatacgct tgtcacagaa gttgatggag atgtaaaaca
    10381 atatcctgca ggaattgctc attttcttga acataaatta tttgaaagag aagattctag
    10441 cgatttgatg tcggctttta cgagtctagg tgcagatagt aatgccttta caagctttac
    10501 aaaaacaaac tatctttttt cagcaacgga ttatttttta gaaaatttag atttacttga
    10561 tgaattgata acatcagcac actttactga agcttccatt ctgacagagc aggatattat
    10621 tcagcaagaa cgagaaatgt accaagatga tccagattcg tgtttattct tttcaacttt
    10681 agcgaatttg tatcctggta cacctttagc aactgatata gttggaagtg aggagtccat
    10741 ttcccaaatc aatctaacta atttgcaaga aaattttaca aagttttaca aacctgtaaa
    10801 catgtctctg tttttagttg gtaattttga tgtggagcga gtacaggact attttgaaag
    10861 caaagaactg aaagattcag attttcagga agtagcaaga gaaaagttgt ttttacagcc
    10921 tgtaaagcta acagatagta tgagaatgga agtatcttct cccaaactag cgattggagt
    10981 tagaggtaag cgagaagttt ctgaagcgga ttgctatcga catcatattt tattaaaatt
    11041 attgtttgca atgatgtttg gttggacttc ggatcgtttt caaaaatgtt atgaatcagg
    11101 taaaattgat gcgtccttat ctctggaagt tgaaataaca agtcgctttc attttgtcat
    11161 gttgacaatg gatacgaaag agccagttgc tttgtctcat caatttagga aggctattcg
    11221 taattttaca aaggatttag atattacaga ggaacattta gatattatca aaagagagat
    11281 gtttggcgaa tttttcagta gcatgaactc tcttgaattt attgcaacgc aatatgatgc
    11341 ttttgaaaat ggtgagacaa tttttgattt gccgaaaatt ttacaggaaa ttactttaga
    11401 ggatgtcctt gatgctggac atcatttaat agatgatggt gacatagttg attttacaat
    11461 atttccatcg tagtaaccta tcataataga cactagaaag aagggatgac aagtatgaga
    11521 aaaaaaacaa ttggagaggt tttacgatta gctagaatca atcagggatt gagtttagat
    11581 gaattgcaga aaaagacaga aatccagtta gatatgttgg aagcaatgga agcagacgat
    11641 ttcgatcaac ttccaagtcc tttttacacg cgttctttct tgaaaaaata tgcatgggct
    11701 gttgagttag atgaccaaat tgttttggat gcttatgatt ctgggagtat gattacttat
    11761 gaggaagtag atgttgatga agatgagttg acaggtcgta gacgttcaag taagaaaaag
    11821 aagaaaaaaa catcattttt acctttattt tattttatcc tttttgcttt atcgatttta
    11881 atttttgtga cttattatgt ttggaactat attcaaactc aaccagagga gccttctctt
    11941 tctaattaca gtgtggttca atcaacaagt tcaactagct ctgttcccca ctcctcaagt
    12001 agtagttctt ctagtataga atcagctata agtgtatcag gcgaaggaaa tcatgtagaa
    12061 atcgcttata agacaagtaa ggaaacagtt aaattgcaat tggcagtttc agatgttaca
    12121 agttgggtca gtgtttcaga aagcgaactt gagggcggtg taaccttatc gccaaagaag
    12181 aaaagtgcag aagcaacagt tgcaactaaa agtcctgtaa caattacgtt aggtgttgta
    12241 aaaggtgttg atttgacagt agataatcag actgttgatt tatcgaaatt aacagctcag
    12301 actggacaaa tcactgtaac ctttactaaa aattaaggaa aaacgaatga aaaaagaaca
    12361 aattcccaat ctcttaacaa taggtcgaat tctctttata cctattttta tctttatttt
    12421 aacgatagga aattcgatag agagtcatat agttgcagct attatctttg ctgttgccag
    12481 tattaccgac tatttagatg gatatttagc tcgtaaatgg aatgtggtca gtaattttgg
    12541 taaatttgca gatcctatgg cggataagtt actagttatg tcggctttta ttatgttgat
    12601 tgagttaggt atggctccgg cttggattgt tgcagtgatt atatgtcgtg agttagctgt
    12661 gacaggttta aggcttttat tggttgaaac tggtggaaca attttagcag cagcaatgcc
    12721 tggaaaaatt aaaactttta gtcagatgtt tgctattatt ttcttgctat tacattggac
    12781 tttgcttggt caagttctac tttatgtagc cttatttttc actatctact ctggctatga
    12841 ctattttaag ggtagtgcct atgtatttaa agggacattt ggttcgaaat gaaatcaata
    12901 attgatgtaa aaaatctttc ttttcgctat aaagaaaatc agaactacta cgatgtgaag
    12961 gatattacgt ttcacgtgaa acgtggagaa tggctttcga ttgtagggca taatggtagt
    13021 ggtaaatcaa cgacggttcg attaattgat ggcttactgg aagcagaatc cggagagatt
    13081 gtaattgatg gccaacgttt gactgaggaa aatgtttgga atatacgtcg tcaaatcggt
    13141 atggtttttc aaaatccaga caatcaattt gttggagcga ctgttgaaga tgatgttgct
    13201 tttggtttgg aaaatcaggg actttctcgt caagaaatga aaaagagagt ggaagaagct
    13261 ctggctttag ttggcatgtt ggactttaaa aagagagagc cagcgcgtct atcaggtggt
    13321 caaaagcaac gtgtggccat tgcaggtgtt gtagccctaa gaccagctat tttaatctta
    13381 gatgaagcaa cgagtatgtt ggatcctgag gggcgtagag aacttattgg gacagtaaaa
    13441 ggaattcgaa aagactatga tatgacggtc atttctatta cccatgattt ggaagaagtc
    13501 gccatgagtg atcgcgtatt ggtcatgaaa aaaggggaaa ttgaatcaac tagtagtcca
    13561 agggagcttt tctctcgaaa tgatttagat caaattggat tagacgatcc ttttgctaat
    13621 caattaaaaa aatctttgag ccagaatggc tatgatttac ctgaaaatta tttgacagaa
    13681 agtgagctag aggataagct atgggaattg ctctagaaaa tgtgaatttt acatatcaag
    13741 aaggtactcc cttagcttca gcagctttgt cggatgtttc tttgacgatt gaagatggct
    13801 cttatacagc tttaattggg cacacaggta gtggtaaatc aactatttta caactcttaa
    13861 atggtttatt ggtgccaaat caagggagtg tgagggtttt tgatacctta atcacctcga
    13921 cttctaaaaa taaagatatt cgtcaaatta gaaaacaggt tggcttggta tttcagtttg
    13981 ctgaaaatca gatttttgaa gaaacggttt tgaaggacgt tgcttttgga ccgcaaaatt
    14041 ttggagtttc tgaagaagat gctgtgaaga ctgcgcgtga gaaactggct ctggttggaa
    14101 ttgatgaatc actttttgat cgtagtccgt ttgagctgtc agggggacaa atgagacgtg
    14161 ttgccattgc aggcatactt gccatggagc cagctatatt agtcttagat gagccaacag
    14221 ctggtctaga tcctctaggg agaaaagagt tgatgaccct gttcaaaaaa ctccaccagt
    14281 cagggatgac catcgtcttg gtaacgcatt tgatggatga tgttgctgaa tatgcgaatc
    14341 aagtctatgt aatggaaaag ggacgtttag taaagggggg caaaccaagt gatgtctttc
    14401 aagacgttgt ttttatggaa gaagttcagt tgggagtacc taaaattacg gccttttgta
    14461 aacgattggc tgatagaggc gtgtcattta aacgattacc gattaagata gaggagttca
    14521 aggagtcgct aaatggatag tatgatttta gggcgttata tcccagggga ttcgattgtt
    14581 caccgattgg atccacgtag caaattgctt gctatgatgc tactgatttt gattgtgttt
    14641 tgggctaata accccttgac gaatctgatt ctttttatag cgacagggat atttattgcc
    14701 ttgtcaggag tatctctttc attttttatt cagggcttga agtctatgtt tttcttgatt
    14761 gccttcacaa ctatttttca actatttttc atttctaatg ggaatgtttt atttgagttt
    14821 tcgtttgtga gaatcacgga ttatgctttg caacaagctg ggattatttt ttgtcgcttt
    14881 gtattgatta ttttcttttc aactttgtta accttaacaa ccatgccttt aagtttggca
    14941 tcagctgtcg aagctttatt agcaccttta aagcgtgtga aagttccagt tcatgaaatt
    15001 ggattgatgc tgtctatgag tttgcgtttt gtcccaacct tgatggatga tacgactcgg
    15061 attatgaatg cacagaaagc tcgtggagtg gattttggag aaggaagcat cgttcaaaaa
    15121 gtaaaggcga tgattcccat tttgattcct ctttttgcga caagtttaaa acgtgcagat
    15181 tccttggcta tcgctatgga agcgcgtggc tatcagggtg gaaaaggcag aagtcaatac
    15241 cgacaattga aatggactct aaaggatacg ctgaccattc ttgttattct cgtacttggt
    15301 tgttgtttat ttttcttaaa atcttagtag ctttcaggaa ttgataaaaa gttactgtaa
    15361 cagtttttga tataaaggta ggaatatgaa ccgttttaaa aaatcaaaat atgtcattat
    15421 tgtttttgtc actgttctgc ttgtgtcagc tctcttagcg acgacttatt caagtacaat
    15481 tgtgacaaaa ttaggagatg gaatctcatt ggttgataga gttgtacaaa aaccttttca
    15541 gtggtttgat tctgtcaaat cagatttggc tcatttgaca cgaacatata atgaaaatga
    15601 aagtttgaag aaacagcttt accaattaga agttaaatca aatgaggtgg aaagtttaaa
    15661 gacagaaaat gaacaactgc gccaattgct tgatatgaag tctaaattgc aagccacaaa
    15721 gactttagca gcagatgtta ttatgcgttc tccggtatct tggaagcagg agttgacctt
    15781 agatgcaggt agatcaaaag gtgcttctga gaacatgtta gctattgcaa atggtggctt
    15841 gattgggagt gtttcaaaag tagaggagaa ctctactata gtcaaccttc tgacaaatac
    15901 ggaaaatgct gataagattt ctgttaaaat tcaacatggc tctactacaa tttatggaat
    15961 tattattggc tatgacaagg aaaatgacgt tcttaaagtt agccaattaa atagtaatag
    16021 cgatattagt gcgggagata aggtgactac tggtggatta ggaaacttta acgttgctga
    16081 tattcctgtt ggtgaagtgg ttgccacaac gcatagtaca gactatttga cacgagaagt
    16141 aactgttaaa ttgagtgcag atactcataa tgtagatgtg atagaattag tggggaattc
    16201 ataatgagac agttgaagcg agttggagta tttttattgc ttcctttctt tgttctaatt
    16261 gacgcccata ttagccagct tctgggctca tttttccccc atgtacattt ggctagtcat
    16321 tttctttttc tatttctctt atttgagacg atagaagtat cagagtatct ctacctagtc
    16381 tattgttttg ttataggctt ggtttatgat gtttactttt tccatctaat agggattaca
    16441 actctcttat ttatcttatt gggagccttc cttcataaat tgaatagtgt tattttgttg
    16501 aatcgttgga caagaatgct agctatgatt gtactgacat tcctgtttga aatgggtagt
    16561 tatcttttgg cttttatggt agggttgaca gtagatagca tgtcgatttt tatagtctat
    16621 agcttggtac cgacgatgat tttaaatttt ttatggatta ctgtttttca atttattttt
    16681 gaaaaatatt atctataaga acgacatata aatgtaacaa aggcgtaata tttattaggc
    16741 ctttttttgg tatactagta ttgtctttaa aagaaggagt atctacgtaa tatgaagaaa
    16801 aaaatcttag cgtcactttt attaagtaca gtaatggttt ctcaagtagc tgttttaaca
    16861 actgcgcatg cagaaacgac tgatgacaaa attgctgctc aagataataa aattagtaac
    16921 ttaacagcac aacaacaaga agcccaaaaa caagttgacc aaattcagga gcaagtatca
    16981 gctattcaag ctgagcagtc taacttgcaa gctgaaaatg atagattaca agcagaatct
    17041 aagaaactcg agggtgagat tacagaactt tctaaaaaca ttgtttctcg taaccaatcg
    17101 ttggaaaaac aagctcgtag tgctcaaaca aatggagccg taactagcta tatcaatacc
    17161 attgtaaact caaaatcaat tacagaagct atttcacgtg ttgctgcaat gagtgaaatc
    17221 gtatctgcaa acaacaaaat gttagaacaa caaaaggcag ataaaaaagc tatttctgaa
    17281 aaacaagtag caaataatga tgctatcaat actgtaattg ctaatcaaca aaaattggct
    17341 gatgatgctc aagcattgac tacgaaacag gcagaactaa aagctgctga attaagtctt
    17401 gctgctgaga aagcgacagc tgaaggggaa aaagcaagtc tattagagca aaaagcagca
    17461 gctgaggcag aggctcgtgc agctgcggtg gcagaagcag cttataaaga aaaacgagct
    17521 agccaacaac aatcagtact tgcttcagca aacactaact taacagctca agtgcaagca
    17581 gtatctgaat ctgcagcagc acctgtccgt gcaaaagttc gtccaacata cagtacaaac
    17641 gcttcaagtt atccaattgg agaatgtaca tggggagtaa aaacattggc accttgggct
    17701 ggagactact ggggtaatgg agcacagtgg gctacaagtg cagcagcagc aggtttccgt
    17761 acaggttcaa cacctcaagt tggagcaatt gcatgttgga atgatggtgg atatggtcac
    17821 gtagcggttg ttacagctgt tgaatcaaca acacgtatcc aagtatcaga atcaaattat
    17881 gcaggtaatc gtacaattgg aaatcaccgt ggatggttca atccaacaac aacttctgaa
    17941 ggttttgtta catatattta tgcagattaa tttacagagg gactcgaata gagccctctt
    18001 ttcaggtttt accgtgacaa tccctattaa aaattatatc aaaatagctt gaaaatattg
    18061 gaaaagtatg gtaaaatgaa aattgtcgtg tgaacgataa tactcattct tgatgaattg
    18121 tgaagcagtt gcccttgggt cgttttgcga gttgaagtca agaagaggaa aaaaacaaaa
    18181 aggagaaata ctcatggcag taatttcaat gaaacaactt cttgaggctg gtgtacactt
    18241 tggtcaccaa actcgtcgct ggaatcctaa gatggctaag tacatcttta ctgaacgtaa
    18301 cggaatccat gttatcgact tgcaacaaac tgtaaaatac gctgaccaag catacgactt
    18361 catgcgtgat gcagcagcta acgatgcagt tgtattgttc gttggtacta agaaacaagc
    18421 agctgatgca gttgctgaag aagcagtacg ttcaggtcaa tacttcatca accaccgttg
    18481 gttgggtgga actcttacaa actggggaac aatccaaaaa cgtatcgctc gtttgaaaga
    18541 aattaaacgt atggaagaag atggaacttt cgaagttctt cctaagaaag aagttgcact
    18601 tcttaacaaa caacgtgcgc gtcttgaaaa attcttgggc ggtatcgaag atatgcctcg
    18661 tatcccagat gtgatgtacg tagttgaccc acataaagag caaatcgctg ttaaagaagc
    18721 taaaaaattg ggaatcccag ttgtagcgat ggttgacacc aatactgatc cagatgatat
    18781 cgatgtaatc atcccagcta acgatgacgc tatccgtgct gttaaattga tcacagctaa
    18841 attggctgac gctattatcg aaggacgtca aggtgaggat gcagtagcag ttgaagcaga
    18901 atttgcagct tcagaaactc aagcagattc aattgaagaa atcgttgaag ttgtagaagg
    18961 cgacaacgct taatttatac aaatagtaat tacctaggag ggcggggctt agcccggctc
    19021 tcctattttc aaaaaatata ggagaattaa aatggcagaa attacagcta aacttgtaaa
    19081 agagttgcgt gaaaaatctg gtgccggtgt tatggacgct aaaaaagcgc ttgtagaaac
    19141 agacggtgac atcgaaaaag cgattgaatt gcttcgtgaa aaaggtatgg ctaaggcagc
    19201 taagaaagct gaccgtgttg ctgcagaagg tttgactggt gtttatgtta acggtaatgt
    19261 tgcagcagtt attgaagtaa acgctgaaac tgacttcgtt gcaaaaaacg ctcaattcgt
    19321 tgaattggta aatactacag ctaaagtcat tgctgaagga aaacctgcta acaacgaaga
    19381 agctcttgct ttgataatgc cttcaggtga aactcttgaa gctgcatacg tatctgcaac
    19441 agcaactatc ggagagaaaa tctcattccg tcgctttgca ttgattgaaa aaacagacgc
    19501 acaacacttt ggagcatacc aacataacgg tggacgtatc ggtgttattt cagttgttga
    19561 aggtggagac gaagcacttg ctaaacaatt gtcaatgcac atcgcagcga tgaaaccaac
    19621 agttctttct tacaaagaat tggatgagca attcgttaaa gatgagttgg cacaattgaa
    19681 tcacgttatc gaccaagaca acgaaagccg tgcaatggtt aataaaccag ctcttccaca
    19741 cttgaagtat ggatcaaaag ctcaattaac tgatgatgtt attgctcaag ctgaagctga
    19801 catcaaagct gaattggctg cagaaggcaa accagaaaaa atctgggaca aaattattcc
    19861 aggtaaaatg gatcgcttca tgcttgataa cactaaagtt gaccaagctt acacacttct
    19921 tgcacaagtt tacatcatgg atgacagcaa gacagttgaa gcataccttg aatcagttaa
    19981 cgcttcggta gttgagtttg ctcgctttga agttggtgaa ggtatcgaga aagctgcaaa
    20041 cgacttcgaa gctgaagttg cagctacaat ggcagcagcc ttgaataact aataatagaa
    20101 aggaagcaaa ttgcttcctt ttttgtatag ggcttagatt tttcctgaaa ttgttttttc
    20161 cccagtctca ctcgattaga ataattaaaa caaaaagccc tataataagg gctaagtgca
    20221 tttaggagac tatacttcaa attcatagta agcgcgttca taacaaggta tctatcctaa
    20281 ttccccaact tccagtatac tagataaaaa ataattatcg gagtaaaggt attgtactat
    20341 gataattcaa ctaagtgatt taggtcaagt tcaccttgtt tgtggcaaga cagatatgag
    20401 gtagggaata gactcattag cctatgtagt taaaacccac tttgaattgg attctttctc
    20461 cggtcaagtc tttctctttt gtggtgaacg taaagaccgc tttaaagccc tttactggga
    20521 tggtcaagga ttttggctac tatataaacg ctttgagaac ggaaaactga cttggctaag
    20581 tacagaaaag gatgtcaaag ctctcgcacc tgaacaagta gattggctta tgaagggctt
    20641 ttctatcact ccaaaatata gtatattgaa actagaatag tacacctctg cttctaaaac
    20701 attgttagaa atcgatttga ctgtcctgat cgatttatcc tgttcttatt tcattttact
    20761 ataaatctat cagaaagttg tgatttctat tgaaatgagg actttctttt tacactcatc
    20821 tgctttcaaa aagcattcta gtccgtctcc gattaacgat ggactttatc acctccttct
    20881 ccagtccttg tatgacatct tcca
//
LOCUS       DAVAZV010000039        20838 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVAZV010000039 DAVAZV010000000
VERSION     DAVAZV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20838
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.039"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            182..658
                     /locus_tag="VQT46_001391"
     CDS             182..658
                     /locus_tag="VQT46_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371412.1"
                     /translation="MKLSLYSEVEHYHFLSSYSLNDITYTDTPKNIIEKSKKDKYRYP
                     IVILNKDHKVIGFFCLHLNTGPKEYGYYQNDYALIRGFSIHDNFRNQGYGSNALNEIF
                     EFIDSTLKLEINHIILAVNEKNILAQKAYRNSGFSVVKKDLEGKRGKLIIMEKSRN"
     gene            complement(1332..1724)
                     /locus_tag="VQT46_001392"
     CDS             complement(1332..1724)
                     /locus_tag="VQT46_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2371413.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLTRQIAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTDKSQYEFLFPSVK
                     IKEEKTDKKEEVATDSSEKAEKKIRREA"
     gene            complement(1702..2163)
                     /locus_tag="VQT46_001393"
     CDS             complement(1702..2163)
                     /locus_tag="VQT46_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET2371414.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVGQLEAELDRSQFEKVEGNRLYMKQDDKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            complement(2126..2386)
                     /locus_tag="VQT46_001394"
     CDS             complement(2126..2386)
                     /locus_tag="VQT46_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371415.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            complement(2391..2819)
                     /locus_tag="VQT46_001395"
     CDS             complement(2391..2819)
                     /locus_tag="VQT46_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET2371416.1"
                     /translation="MEGQIVKSMIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVE
                     EQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLTVPKGIQAPSGQSITF
                     DRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            complement(2788..3114)
                     /locus_tag="VQT46_001396"
     CDS             complement(2788..3114)
                     /locus_tag="VQT46_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HET2371417.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQGDGRITEEQVKAYNEYYTKNGGA
                     NRKVND"
     gene            complement(3116..4132)
                     /locus_tag="VQT46_001397"
     CDS             complement(3116..4132)
                     /locus_tag="VQT46_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET2371418.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            complement(4080..5021)
                     /locus_tag="VQT46_001398"
     CDS             complement(4080..5021)
                     /locus_tag="VQT46_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET2371419.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            complement(5097..5462)
                     /locus_tag="VQT46_001399"
     CDS             complement(5097..5462)
                     /locus_tag="VQT46_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET2371420.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            complement(5613..6671)
                     /locus_tag="VQT46_001400"
     CDS             complement(5613..6671)
                     /locus_tag="VQT46_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET2371421.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQT46_001401"
     CDS             complement(6834..7985)
                     /gene="nagA"
                     /locus_tag="VQT46_001401"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET2371422.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            complement(8138..9955)
                     /locus_tag="VQT46_001402"
     CDS             complement(8138..9955)
                     /locus_tag="VQT46_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET2371423.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQT46_001403"
     CDS             complement(10056..11198)
                     /gene="tgt"
                     /locus_tag="VQT46_001403"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET2371424.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAECGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11328..12185
                     /locus_tag="VQT46_001404"
     CDS             11328..12185
                     /locus_tag="VQT46_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET2371425.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQT46_001405"
     CDS             complement(12213..12857)
                     /gene="pcp"
                     /locus_tag="VQT46_001405"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET2371426.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(12964..13332)
                     /locus_tag="VQT46_001406"
     CDS             complement(12964..13332)
                     /locus_tag="VQT46_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET2371427.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATRSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLWYGIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            complement(13343..13768)
                     /locus_tag="VQT46_001407"
     CDS             complement(13343..13768)
                     /locus_tag="VQT46_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2371428.1"
                     /translation="MIEIQDLLYQLRLSEQASTQLFEKRLGISLTRYQILLFLLEHSP
                     CNQMAVQERLKIDQAALTRHFKILETEGLVERHRNPENQREVLVEAAKYAKEQLVVNP
                     PLQHIKVKEEMESILTEFERTELSRLLNKLVLGIENIEI"
     gene            complement(14193..15335)
                     /locus_tag="VQT46_001408"
     CDS             complement(14193..15335)
                     /locus_tag="VQT46_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2371429.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETSSAVAEEAPQGTTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            complement(15501..16121)
                     /locus_tag="VQT46_001409"
     CDS             complement(15501..16121)
                     /locus_tag="VQT46_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2371430.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNTFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            complement(16125..17405)
                     /locus_tag="VQT46_001410"
     CDS             complement(16125..17405)
                     /locus_tag="VQT46_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2371431.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            complement(17466..18950)
                     /locus_tag="VQT46_001411"
     CDS             complement(17466..18950)
                     /locus_tag="VQT46_001411"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET2371432.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            complement(19026..20303)
                     /locus_tag="VQT46_001412"
     CDS             complement(19026..20303)
                     /locus_tag="VQT46_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET2371433.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            complement(20410..20493)
                     /locus_tag="VQT46_001413"
     tRNA            complement(20410..20493)
                     /locus_tag="VQT46_001413"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20457..20459),aa:Leu,seq:caa)
     gene            complement(20503..20574)
                     /locus_tag="VQT46_001414"
     tRNA            complement(20503..20574)
                     /locus_tag="VQT46_001414"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20540..20542),aa:Gln,seq:ttg)
     gene            complement(20588..20660)
                     /locus_tag="VQT46_001415"
     tRNA            complement(20588..20660)
                     /locus_tag="VQT46_001415"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20625..20627),aa:His,seq:gtg)
     gene            complement(20675..20745)
                     /locus_tag="VQT46_001416"
     tRNA            complement(20675..20745)
                     /locus_tag="VQT46_001416"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20711..20713),aa:Trp,seq:cca)
     gene            complement(20750..20830)
                     /locus_tag="VQT46_001417"
     tRNA            complement(20750..20830)
                     /locus_tag="VQT46_001417"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20794..20796),aa:Tyr,seq:gta)
BASE COUNT         6236 a         4735 c         3669 g         6198 t
ORIGIN      
        1 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata atgaaaataa
       61 aggactaaag caataactct aaatacatct gatttttata ggatatttca taaaaaaaat
      121 ctacatacct agagtcctat ttagttatgt atcttacata aagagaaagg aattaattat
      181 catgaaatta tctttgtata gtgaagttga acattaccat tttttaagtt cttattcttt
      241 aaatgatatt acatatactg ataccccaaa aaatattatt gaaaagtcta aaaaagataa
      301 gtatagatac ccaatagtaa tacttaataa agaccataaa gtaattggat ttttttgcct
      361 acacctaaac actggtccta aagagtatgg ctattatcaa aatgattatg cgcttattag
      421 aggattttct attcatgata atttcagaaa tcaaggatat ggttctaatg ctctgaatga
      481 aatatttgaa ttcatagact caactttaaa attagaaatt aaccatatta tattggctgt
      541 aaatgaaaaa aatatattgg ctcaaaaagc atatagaaat tccggttttt ctgttgtgaa
      601 aaaagattta gaaggaaaaa gggggaaatt aattattatg gagaaaagca gaaactagta
      661 atgatactag tttctgcttt tctctaagtc tgctataaat ttataacatg ttgaaataag
      721 atgtgaataa attgattgca gaattcaaac caatttctaa caatgtttta gaaaactcgg
      781 cggactattc cagattcaat ccactatatt ctatcttatt tgcatatttt gagagaaata
      841 atctatatac taaactttta tgtttataat tcattccttt cgtttcactc aaggcacaag
      901 acagaatgaa aaagtggtgt gctctttatt ttgttttata ataatagtga gaaaacctat
      961 cactactaca aatcacgggg aggtgaataa gtgagtggta tagccactac ctcgcatttt
     1021 tataggtgtc attctttcca tcaagcacaa gaactgtgac taggagcacg taaacttata
     1081 attgaataag cgactcgttt gtgaaaggaa agaatagtca agggataggc agactcaaat
     1141 ttggtgaagg gaaacccctc atgttaaaag ccaaacttca attttaaaaa ttttaaaatt
     1201 tgtttcgtat tcactactcc ttgcctttat attggattga ttaagagaac ctttcgcgtt
     1261 tctagaaact acagtggact attctggatt caacgcatta tagttgaatt gactaggaat
     1321 tctctttctt ttcaggcttc tcttctgatt tttttctccg ctttttcgct tgaatcagtc
     1381 gctacctctt cctttttatc cgttttctct tctttgattt tgactgaagg aaacagaaac
     1441 tcatattgac tcttatccgt acgaacagtc gtcaccaagc ttgttttctt gttttgatag
     1501 ctcacctgac ctagattaaa aacctgttcc ccactttctt gctcggcttt atccttggtt
     1561 cgtttagcca tggcaaaagc aaccaatttt tctttattta aagcatagtc ttgatagtgg
     1621 gcgatttgtc gggtcaaata aaattgcaac aaaagactaa agatggctgc tatggtgact
     1681 gcgtagagga gaacacctgc cttaactttc ttctttttcc acacgataga tgaactccct
     1741 ttctaagcct ttttgaaact ggaaacgaaa atgaaccagt tgattgtcct ctgtaatctg
     1801 agctgatttg aggccataaa ccataggctg atacccccgt ccactagcat cggttttacg
     1861 aaaatcgtct gactttgact taccgatggc gatgtccttg tcatcttgct tcatgtatag
     1921 gcgattgcct tctacttttt cgaactgcga acggtctaat tctgcctcaa gttggcccac
     1981 aaacaagagc cactcctttt gctcgctttg ttgctggtag cgaacttctg aaatgaggag
     2041 ctgactcata gcttgaaaaa ggagtaatcc cccactgatg acaatgaggg caagcaggga
     2101 ttctaacaag gtaaaagcct tgaccttatg gctctttgat tgccaacaac tgttctgaac
     2161 catggtagac ctccaatccc ttttcactag aaaatacctg aatctcaact ccgttgatgc
     2221 ttacctgatt ttgccccgtc tgcaaggcca tcttagctac cctcaagact tcttcctttt
     2281 gcaagatttt tgcttcctct tgcctatttt tttgaatttg tcccaaaagg agggtcgcaa
     2341 tgctggcaaa gatagctaga gcgactactg cttccagtaa aatcactgcc ctaatttttt
     2401 gtttccttaa tgcgtttaat ttttccattt cctagatata attgatagcg aatcgctcct
     2461 ttactggtct gaaattcaac cttagccagg gacgaattgc ccccagctcg gtcaaatgta
     2521 atactttggc ctgatggtgc ctgaattcct ttaggaactg tcaacttttg actgccattg
     2581 ctaatcatct gcccatccaa gttcagacta gtcttttgtt gactagctac actgcgtttt
     2641 tgggtttccc gatagagttc ttcaaactcc ataaagaaaa tctgttcctc taccgctgca
     2701 aaagtggact ggacagagcc ggacaagccc aaggcaagga tactcacaag tcccaaaacc
     2761 aagagacttt ccagcatggt aaaggcctta atcattgact ttacgatttg cccctccatt
     2821 tttagtatag tattcattat aagctttaac ctgttcttcc gtgatgcgcc catctccttg
     2881 taacttgctc agagtagcat cttcattttt atccaagcta taaagttctg cctggctttc
     2941 caccacctta acaacagctg cttttccttt gtcattgact gcttcttttt gcttggtcag
     3001 attaggtaca aagagcaaga aaagcacgct gataatcagc aagaccacca acatctccac
     3061 caatgtaaaa gctttaacct tagctttttt caagaatgtc atcatttttt tcattttaaa
     3121 aatttacctc catattttga tacatgggca tgagcattgc cgcataaagt aaaacgataa
     3181 tcagtgccac aaagataaaa accagtggct gcaccaaatt catggtgcgg ttgactcggg
     3241 taaaaaaggc ttcccaagtt ttttcagcat agatttccaa ctcactaccc agcttggact
     3301 taacttcccc atactctatg atgagactca attccttcct aaagaaagga taggttccta
     3361 tcgtctgaga aaattcacgg ccatttttca gggtttgagc cagatcttga ccgatttctt
     3421 taaagagctg ggaaccttgt tcctgcatca tttgaaaaat ctgcgtcagc tccattccct
     3481 gtgaaatcat attcccccat tcacgtgcat aataggctgt caagtaggtc tgcacaaaga
     3541 ttccaataaa gggaaggcgt gctaagatag aaaagacact catcttagaa cttcttttat
     3601 aaaaagttag tgctaaaagg gcaagcacgg aaacaagccc taccatgcct agaaaaattt
     3661 gtggcagatt accgataatt cgggtggcaa tattgctact atccagttgt gggagcaggt
     3721 aattccgtag ccccagcata attaagagaa gaaaatccag caaaatcaaa ggataggtcg
     3781 ctacttcaat taactttttc ttgaccttgg ccagattgtc tagatattct tctatctttc
     3841 ccaaactcag gtgaagattg ccatgaactt cagctagaga taactgagtg acaatggtac
     3901 ttgaacatcc caaactttcc atcatttctg agaatgattt cccctgagac aagcctgtac
     3961 gcatctgggt cacacactgc ttgtccaaca aggaactcct atctaaaaag gagatagtct
     4021 ccaccagatg aaaaccgcta gaaaagagat tgttaaatag ggtgatgata tttttttgct
     4081 tagctgtagc taattttttc cgtctcagcc tgaagacttg tgatatgtcc atctttaaga
     4141 agttggtcaa tttgctcatt ccacttggct gcttggtgtt cttgataatc tctgtttgca
     4201 aagtcaacga ttcctcctcc cccgattaat ctctggtagc agactccttg cagaacaact
     4261 gccaattctt cttcactcac acccaactcc agcagacgct cataaacacc tcggatactc
     4321 ttggcgtgaa tggttgaaaa gactgtcgca cctgtcaaac tagctctgac cactgcacgc
     4381 gccgtctcgc tgtcacgaat ttctccgata atcaagagat ctggtcgatg acgcaaggaa
     4441 agtttgatta gattttcata ggttaggccg attgcttcgt tcaactgcaa ctgaagcatg
     4501 tcgtcctgct tgatttcgac aggatcttcg atggacataa cttgctgtcc tttaaagagt
     4561 gacttggaca attcatgcat caaggtcgtc ttaccactcc caaccgggcc agcaaaaaga
     4621 tagagtcccc gttgcctgta ctgcttgcct aattcttcaa tatcctgaaa ccaaaaatgc
     4681 aagtcctgct cctcatcgtg caacaaacgg ataaccaaac tctcatgccc ccgataatcg
     4741 cctacagtag ataaacgtag agacgccatc ttctggtcat aggcataatc acaggaaccc
     4801 agttgactac gtcttttttc tcccacattc atacccgcca caaacttaaa gtgactgata
     4861 acggctgcaa acttttcaaa atcatagcta ccaattttac agcgctcgtc tcctaccctc
     4921 atatgaagct cataggcgtc taacttaggg acaaaataaa tatcctgcgt cccttttttc
     4981 cgagctgaac gaatgatttc ttgtgcaatt tcttgaacca tacttacctc ctcacctata
     5041 ctattcgcaa agcgttagaa aaataaaaaa agcaactcca aaaaagttac ttttctctat
     5101 tttaatttca tacggcaaga acgattcctt tcctgactgg tttgtttttc atagcctgag
     5161 cgtagttttt cgtctgggat aacctgctca tcctgcaaaa gagccaaaga atggtattgt
     5221 tgtaaatact catcacattc atcacaccag cgttggtctt ccgggtccca aaaaatggtc
     5281 atcaagtcgc ttctactttt ataaagaggg gattcttgtt ccaatctaaa ccagcaagtt
     5341 ttgtagtatt tgagagcatc ataatactgg tcaaattttc tacttgctac aatatcttct
     5401 tcccaacctt ctaagaacca ccacggttca aaatctccgt acatttctat aacacgatac
     5461 atattcattc attcctttgt accgtatatt ataaccaatt ccgccagaca aggaaagaaa
     5521 tatgctcatt tcttaatttt ttgataaaaa atccagccat ctgatggatg actgaatttc
     5581 tatttgctta tgtacaaaaa tatttttact acttaggctt ctgagatatc gttttcgata
     5641 atgaccttaa tggcatggtg gtctgctgcc ttactgaaga cttcgtaggc tttttcaatt
     5701 tcactgagtt tgaaatagtg agttaccaat ttttccggtt caatcttatg actttcaagt
     5761 gctttcaaca attgtggagt cgtatttgta gataccaaac cagttgttac attgatgttg
     5821 cgaatccaaa gtttatctaa atcgaattca actggtttac catgcacacc acagttggca
     5881 accgttccgt ctacaccgat aatcttttga cagaaatcaa atgtttcagg aatccctaca
     5941 gcttcgatag cgacatccac accacgacca tctgtcaaat cataaatttc tttaatggct
     6001 tttttagggt ctgaagaatt aaccttatga gtcgcaccga atgatagggc agtttccaag
     6061 cggttatcgt ctaggtctac cataatcaat ttagctggtg aatagaattg ggctgttaaa
     6121 agagcagcca atccaactgg acctgaacca ataatggcta cgctgcaacc aggttctact
     6181 ttccctttta agacaccaat ttcatatcca gtaggcagaa tgtctgacag cataaccaaa
     6241 gcttcatctg acaagtcttc tggagtatgg taaagagtat tatctgcatg agggacacgt
     6301 agatattcag cctgcatacc atcaatcaag tgaccgaaaa tccagccccc ttcgtcttca
     6361 cagtgggcat aaattccttt tttacagtag tagcatttac cacaggcaca gacgcaagaa
     6421 atcaagacct tgtcaccttt tttgaagttg gaaactcctt ccccaacttc ttcaacaatc
     6481 ccaatccctt cgtggccaag aatggtacca ctttggcaag taggaacatc ccctttgata
     6541 atatggaggt ctgttccaca aatagtggtt tttacaatac gcacaatagc gtctgttggc
     6601 ttgcgaataa ctggtttgtc tacatcaaca aaagaagcaa gtcctggttt aacataagta
     6661 taggctttca taaagcactc ctccgttttt ttatttgtaa tatttatagt tcaattgtaa
     6721 gcctttttct ttgtttcttc aagctttttt tgtgattttt ttaacttttt atttaccagt
     6781 aaagtaccct gtataaaaaa gcagaagcta gtctctaact tctgccttct ctcttatgct
     6841 tgataacgtt tcacaccatc taggtaggtt gctaccaatt ccaaatcttt atctaatacg
     6901 atgaagtcag cgtcgtagcc ttcacggatt tggccacaga cgtcatcgat gtgaacggat
     6961 ttagctgggt tgaagctggc catcatgact gcttcatgcg gattcgcaat tccccattcg
     7021 accacattct tcaaaccatc tttgagtttg aggatagaac ctgccaagtt acctgtcgat
     7081 ttgaggcgtg cagttccatt tgcaacgaca actgggaatt ctcccaacat ataatctccg
     7141 tcttccaatc ccccagctgt catacagtct gtgataagag cgatgttttc tgttcctttt
     7201 tgtttgataa gaatttcgca agcctttgga tctacgtggt gaccatcaca gatcaactct
     7261 gcataggtat gtggcaattg gtacatggct ccaaccatac ccaattcacg gtgagtcaac
     7321 ccacgcattc cattgtaggc atgcacccaa acactcgctc cagcatcgac tgcttttttg
     7381 gcttcatcaa aagtcgcgtt tgaatgtcca agagcaaccg tcacaccttc gcccgtaact
     7441 gtacgaacaa agtcttccac cccatcacgt tctggtgcaa gggcaatttt attaagcaag
     7501 ccatttgccg ctttttgcca agaatgaaac tcctcaacac ccgggtctct catataagtt
     7561 ggattttgtg cccccttaaa agtttctgtg aaatatggac cttcataata aatcccacga
     7621 atcttagcac ctgttgcttc tttataatgg tttccaagat tttcagtgac tgcaagcaat
     7681 tgctcataag tggctgttaa agttgtgggt aagaaactgg taacaccggt actaagaagt
     7741 ccttcactca tagtatgcaa tgtaccttca atgttgttgt ccatcacatc tacacctgca
     7801 tatccatgaa tatgagtatc cacaagtcct ggggcaatgc tataacctgt atagtcaatc
     7861 acctcagccc cttcaggaat ctgctctaca tgtttcccaa acttgccgtc cacaagttcc
     7921 aagtaaccac ctcgacgaac tccgtgtggg tagaaaaact gatccgcttt aatatagtta
     7981 ggcataatgt taacctcctt aaaagattga ttctacaatt tattatgtca attacattat
     8041 aaacctttct tttttatttg taaatggtat agacctattt tttggagata ttttaaaaga
     8101 gctggatttc tccaactctt ctctttttta atacaagtta ttttgattta accggcttgt
     8161 cttgagctgt ctgcaaagct gtggcaatcg tatctgcata caattttgct cctgcttcga
     8221 tagtgctact ctcactcccg aaatgaacct ggtctgttcc agcccaaatt tctggatgct
     8281 ctttcgcaac ttgattccaa tctgctatcg taatgtaagg tgtcttctct gccaattctc
     8341 tcatataggc agcagccttc tcaacgatgg cataggtctc ttttgtctta tctccctcat
     8401 aaggagtcac caaaatcata tggtgtccct taggaagatt tttcacgata ctgtcccagt
     8461 catccttgta attctcagga ttatttaccc cagtcgcaat gaccaccgtc ttaggtaaaa
     8521 atttattctg gctattattt agcatgattt catttgcggt cttggttgtt acgctgacct
     8581 gcgcgttaat ctgtgctcca ggaagagctg tctgtagtgc tgtatttgcc cttaaagcca
     8641 ctgagtcacc aattaacata gtgccatcag caattcccaa actgtttgca tctgcccgtt
     8701 ctgccatcac cttggtctgg ccaatatttg ttgcagcttg cttcaagcca ttgacagtca
     8761 agtctgtctc aaacgctccc acttgtggtg ccaacaaggt caccatgcag acaatgaagg
     8821 tcaagattcc tgtacctgct gcaagaattg cgtgaatata aggcagggga cgaagagttt
     8881 gtaaaatagg tgtgttcttg cctgcaatcc aaggttccaa tacataaaat gacagactgg
     8941 caaagccata agaacaaatc agagtcagta atacagcaag aagatttgat gtcaactgtg
     9001 agaaaatgat atagaaaggc caatggaaaa gataaaccgc atagctagta tccgctaaaa
     9061 agctgataat cttcggctcc tgtatatgat gtgtcttttc atgtaagaca cgcgccgcca
     9121 gaatcatggc aagagctgca agactggcaa gcaagaagcc gataagatag gcaaaaagat
     9181 aagtgaattt gacaaagaaa gtcaaaagaa ctaggaaacc aaagcctcct ccaaaaacta
     9241 ctaaagtctt tcgtaaatcc cagattttat ccaactgctt gacgagggaa gtcgtctgac
     9301 gaacgcctac aatagttgct aacatacttc ccaaaaagaa tggatagaca tgagttaaac
     9361 tggagaaata aacagaggaa taagaggtca ctagaaaact accaataaac atggagaaga
     9421 aactgatcaa gaaggcagta gcagataaga gaaagatcat ccccttcaac tgaccatttg
     9481 atttagcttg tttggataag aaccaaactg ccaatcccca aagaatatag tagtgaacct
     9541 caactgccaa actccaatta tgaacaaaca aatgaggaat gaactgagat tcataactcc
     9601 cacctgttaa gagttcatag aagttggtca taaagcctaa gacgcccgca atctggccac
     9661 caattccagc aacatagtct tggcgaacca agaaagtaaa aggcatggtc accaagacca
     9721 tcaaaaccac aggtggcaca atccgataaa agcgtcttct aaaaaatcct atcaaatcaa
     9781 tctcattgtt cttagaaaat tcttcaatga gtagagctgt aatcaggaaa cctgaaaatg
     9841 tgaaaaagac atctaccccg aaaaatcctc caggaaagat cgtctgaaag aagtgataca
     9901 agagtaccaa aagtaaacct ataatcctaa tcaaggaaaa ccatttaatg cgcatacgag
     9961 tttattcttc ctttcattgt acactttatt ctatcaaaaa aagaagaaaa atcctaagag
    10021 aaaacttagg atttttagct tatatcaatt ccattttaga aattacgtcc tgacttatta
    10081 tagccatatt tttccacaaa atacttacgg aattccaaga gattgtcatc catgatggct
    10141 tgtcgcactt gcttcatcag gttaagcaag aagtaaagat tgtggtagct agtcaagcgg
    10201 ataccaaagg tttcatcagc cttgagcagg tgacgaaggt aagcgcgtgt atagttatta
    10261 catgtgtagc aatcacactc aggatccagt ggcgtaaagt cctcagcaaa ctgggcattt
    10321 ttcacaacca aacgtccttg actggtcata caagtcccgt tacgagcaat tcgagtcggt
    10381 aagacacagt caaacatatc caccccacga atgaccccat cgatcaagct atctggcgct
    10441 cccacaccca tcagataacg aggtttattt tcaggcagca gttgagttgt aaagtccaag
    10501 accgcattca tctcttcatg ggtttctccc actgccaaac caccgataga gtagcctgag
    10561 aaatccatgc tgacaagatc gtgagctgat tggcggcgaa ggtcttcaaa tcctgcacct
    10621 tgcacaattc caaacaaacc ttggtcatgt ggacgacggt gagccttcaa accacactca
    10681 gcccaacggc tggtacgctc gatcgatttc ttaacgtagt cataaggttg ataaaactga
    10741 ggacattcat caaaggacat catgatgtct gaacccagat tattctgaat agagatggct
    10801 ttttctgggg ataggagcat cttagaacca tttagatgat ttttaaaggt tactccttct
    10861 tctgtgatat tacggctatc tgctaaagaa taaacctgaa aaccaccact atctgtcaag
    10921 ataggctggt cccaattcat gaacttgtgg agaccaccag cgcgtgcaat gagttcatct
    10981 ccagggcgaa gccagagatg ataggtgttt gataggataa ttcccgaacc catctccttc
    11041 aattcttcag gtgactgagt tttgacagtg gcttgtgtcc caactggcat aaacataggt
    11101 gtcggaaagg taccgtgggg agtgatgatt tctcctagac gagctcctgt gtgtttttct
    11161 ttcttaatca aacgatattt gattggtgaa tctgacattt tttacctccg aagctgggaa
    11221 agacagtccc agttcataca gtgtgcccaa ggacacactg tatgatttta tcaaaaaaag
    11281 taggaactgt cacgaactat gtataagaac tatggtataa taagagaatg aactatccaa
    11341 aaattgattt aaaaacaatt cgtcaggagt caaaacattt tcaggctgac accccccgtc
    11401 tctttctcct ctatatcctt cccagtatgc tggtcatctt atctggtttt cttaatccct
    11461 tatctcggat ccacgggact gttttagaac agccattttt cagcatactt ggccaaatac
    11521 ttcaaaccta cctctttcct ctactagtct cctttatcgg gactattctt ttgaccagtt
    11581 ccgtctatgc aacactgaca ctcatgaaag attctaaaac ggagccatct gtaaaaaaca
    11641 gcctagctct ctttgatgag gagcgctttt ctcaaacctt tttgacccta cttctcaaac
    11701 gtttctatct ctttttatgg agtatcccta atttacttgg gatttacctc ctcttttata
    11761 gtagcttttt agccaaaaaa ttcgtcaccc tacatcctga gtttccaaat ctagatctct
    11821 catcagttga aaccgagcgt ttcctcatgg tctttggact ctactttctt gcaagtctca
    11881 tcttgatcat tgtaggaaat atcctctata ttccacagta ttatgcctat tcacaggtgg
    11941 aatttcttct ctgttatagt ctagacctag gacaggtccc accaagacga atcctaaaaa
    12001 ctagccgttc ctttatgaag ggctacaagt tccagcactt tgtcctagat ttacagcttc
    12061 ttccttggta cttcctcaat tggattacct ttggcattgc tagtttttca ctcctacctt
    12121 atatccaatg cactaaaatt atgttttacc gagcagtatt ggctcgaaaa cgtccaaaag
    12181 cttgaaggtt tttcccctca agcttttttc tatcaatgag tttctccgcc taccaacttg
    12241 agttcctgat ctccatgttc tatcatagcg ccgattgctg cttctatccc tcgccgaata
    12301 tccactaaac tcatagttgg agtagtcggt ctgttcacca cctgttccat catataagga
    12361 atatgcataa aacctgcctt aacatatgga aatttctttt ctaccaaata gagagcctga
    12421 tacatcaaat ggctgcagac aaaagtccct gccgtattgg aaacagaggc cggtaagccc
    12481 tcttttttta tagcttgaac catcgcttta atcggcaaac tactaaagta ggccgaagca
    12541 ccatctgggc gaatgggacg gtcaatcggt tgattatctt cgttatcaga aatgcgtgca
    12601 tcgtcttgat taatggccac tcgttcaggt gtcacactag ttcttccacc agcttgccca
    12661 atacaaagga caaagtcagg ttgataacga ttcatctctt cttccaatac ttgagcagat
    12721 ttgtgaaaaa ctgtcggcac ctctagccaa cggacctcag caccatggat ttcagctggt
    12781 aaacctttaa tggcctccaa agttggattg cccttttccc ctccaaaggg ctcaaaacct
    12841 gtcactaata ctttcatttc taactcctca aaaccaattc aatgagactt ttttcttaaa
    12901 aacaagtata acatatttcc cttattctgg attaaaaagg attagcgaga ttaaaatcga
    12961 ccttcaagtg tatttaaaga gtaaaatact aatcaaggcc aaaatagctg atccaccttg
    13021 cttcaaaata atttttttat ccgctgttaa agagccgtaa gtcgcagcac caatcacaaa
    13081 taagacaaaa atagtcacaa tttctaaatt ctgtgagaaa taaatgccat accagagaaa
    13141 gactcctagc agagccttat aaatcccttg atttttgaac aatgaactta ctgacggatg
    13201 agccaattct tccttttcca tattaaatac acgactagtc gcatctgatc gcgtagcaat
    13261 actttccaaa taaaaaatgt aaaaatgctc caaagcaacg atcgttgtta aaataattgt
    13321 aataattgac atctatttct ccttaaattt ctatattttc aatacccaaa accaatttat
    13381 ttaataaacg gctgagttct gttctctcaa actctgttaa gatactttcc atctcttcct
    13441 taaccttgat atgttgcaga gggggattca ccactaactg ctccttggca tacttcgcag
    13501 cctctaccaa cacttcccgc tgattttcag gattacgatg acgctccacc aaaccttccg
    13561 tttccaaaat cttgaaatgc cgtgtcaaag cagcctgatc aattttcaaa cgctcctgaa
    13621 ccgccatttg gttacaagga gaatgctcca gcaaaaacag taaaatctga taccgtgtca
    13681 aactaatccc aagccttttt tcaaacaatt gcgtactcgc ttgctcagac aagcggagtt
    13741 gatacagtaa atcttgaatc tctatcattt cttcctccta tccattgact tatcaatagt
    13801 tgaccaatca attataatat aaagtatagt gaaatgaaat aagagcagga caaatcgatc
    13861 aggacagtca aatcgatttc taacaatgtt ttagaagcag ttgtgtacta ttctagtttc
    13921 aatctactat aaaatagatt gcaagaatgt tgcttagatt attacaagat gataactttc
    13981 cattttccat tcaaattgat actcaatgaa aatcaaaaag caaactagga agctagtcgc
    14041 aggttgctca aagcacagct ttgaggtttc agataaaact gacgtggttt gaagagattt
    14101 tcgaagagta tgacaaagaa aaaacgaacg agaatcgctt cccatcacga aagctagatc
    14161 tcattcgtca aaatgatgtt accaagtcgg gtttatccat tcattgaaac gtgaacgtga
    14221 tcatagtgat tttctgtcac actaccacgg tctggcattg ggttccaagt gttagctggc
    14281 ccatatttgc tatcgaatgg agcatagaaa cgttgtttcc agatgatgta actaatgcca
    14341 cggctggcca tgttttgaat agcatattcc gcaatcttat cccctaattc tgaacgttct
    14401 ggtaccataa agtcgatagc caaacctttt ccgtgatctc cactgtctcc tggacgataa
    14461 ccgctaaagg atgtaatgcc aaacaagtta gcaatttctt ctttaaaggc agctgtttgt
    14521 ggttgaagac ctgcattttc agattttgct actgcaagtc cagcataatc gggcgcagct
    14581 ggagcctcgt aagttgttga aattattttc gtctcttctg gttgataagt agaaactgct
    14641 gctgtagctc catttgatga tgctacttct tttgcttctg aacttgttgt agttgcttcc
    14701 actgctgatg cagcttgagg gcttgcttgt gtttcctgct tctcagctgg agtcgttccc
    14761 tgaggagctt cttctgcaac tgcactgctt gtttcggccg tttgctcctc tgggacagaa
    14821 gtgcccgtag atggtgccac ttcttcagaa gcaatcactg tctttgtaac ttctgaactt
    14881 gatgctactt cttttggagc ttctgcaatt ggttgagaaa ggtctgcaac ctgaacagtt
    14941 tgatcatcaa cggtcacttg attagtggtc aaatctgctg tcgcagttgt cacttcttca
    15001 ctagagtctg cttgaggtgt ttggatttca acttctgtta cttcttctgc ttcattgaca
    15061 gtcgttgtca aaacagtttc tgggaaaatc aagtccatat tagtgatttt gttcagattc
    15121 gcaagcactg tgacatctac acccaaggct tctgcaatgg tgctcaaagt atcaccatac
    15181 tgtacggtat aacttgtttt gttgtccgtt ttagtcaaat cgttttggat ttgctcaaca
    15241 ctacgtgcag tccaaagaac ttcttctgct tgagttgcca atactggggc aaatgacaag
    15301 gctactgttg acgctaataa cattcttttc ttcattcttt caaattcctt tcaaatgagt
    15361 acctgtctat cataacacaa aaaatgtaga aaaaaagccc tctcgggcct atttaacaga
    15421 actgtctatt ccttgtaaca aactagatta cttgaaatag tttgttaggt ctctgtcaca
    15481 aaactgacac aatcttttta tcacttagtc tcaaaaatac gggaaatatc tgctaacgct
    15541 tgaatcctgt gattcccttc ataagtagac tctaaaaagt tgatactttg aatcccacta
    15601 ttctgggcaa attccacatc cagagtccga tcccctatat aataagtatt atcagaattc
    15661 aactgatact tatctagcag ataggtagcc gcttctggac ttggcttccg cacaaagcca
    15721 ctctgactgg tcaaaatctc tgtaaaatag gattccaccc ccaagtcctt gagaatggta
    15781 aaagtgttgt tccccttatg agtatatata aactgctgaa ttcctgattc gtctgcccaa
    15841 gctagcacct cacgcgcacc tggcatcaaa actacctgag cattcttctc agccagactc
    15901 tgggcacgca cctgatttag cacctcaaca tccagatttc tatcttctgc cacccgcaca
    15961 agcaaatttt gcaccgaata cttgaagata aactctctca ccttctcctt atcataagga
    16021 atagaaaact gagcaaaagt ctcctcaatc cctgataaaa tcgcttcgta agagtccaat
    16081 aaagtcccgt ctaaatccca aataaaagct gttttttgca tttcctatcc tttcaagctc
    16141 atatagcgct ggtaacgata gcgtagaaat aaccagcgaa aaccattatc caagagagac
    16201 cctgcccaaa taccaggcaa gccccaacca agcacaatac ccatcagata tcctgtccca
    16261 atgcggatac accacatgcc tatacttgtc gcataaaaag ggaggcgtgc atttcctaat
    16321 ccctgccaga ctgccgtata gatgactgtt cctgtcgtca taggggtacc aagtagtgaa
    16381 aacagtgtca ctagaacact agcctccacc gctagagaat cagtcgtata gagatgagtt
    16441 aatggtacac ccaagacata tatactaaag gacaggggca acatgaggaa cagagaaagc
    16501 caaaaggttt gtttactcaa actagcaact cttttccaat catcctctcc aactgctcgg
    16561 gccaacagca tgaccgttgc cgtagcgaca ccaaaggcag gcatatagtt aaactgggtc
    16621 aagacttctc cgattgcatt cccagcaact gcctccgtcc caaaagaaac gaccaaggca
    16681 atgatcacta catctccagc cctcatcata agtcgctctc cagctgctgg taaagccaag
    16741 gtcaacagtt ccttatctaa accaaaagtt agcttcccat aaggcagttt taattgtgac
    16801 cacaaaatca caagaccaac caaacgagac agaattgtcc cccaagcaac accagctatc
    16861 cccatatcca gaacaaaaat agctagactt gaaaaaagaa tattcaaggc attggataaa
    16921 aaactaacat agagaggcag acgtggatta tgcgttgcac gaatcaaggc tcccaaacta
    16981 gtcattaaac ctaagagaac aatcgatccg cctaccaaag atagatacag tccaccactc
    17041 tcagctacat ccctctccgt ccccaaaagt cctatcatct ctttcccagc gaagatggac
    17101 aaaaatccta aaaggaaact taatagtaag gtaatcttca acgcctcagt cacatgatag
    17161 gccaacttcg actggtcttt ctgccctatg ctttttgaaa taacactgga aatagcagct
    17221 cccagagcga tgaaaatcgc ctgataaatg gtgataatat taccagctac tgaaacccct
    17281 gaaatagcta tcaatcctaa atgagcaacc aaataactgt ccaccattcc cattagcatc
    17341 tgcaaaaagt tttcacccat agctggcaat gcaatattaa gaatgtcttt atttttctta
    17401 aacaatctct cctcctgatg aaaagaaact cagttggttt cccaaccgag tttgctccct
    17461 ctgtcttaaa gtcctaaata agcctcaacc gctgcttgca tgtcagcagc tgccactgtt
    17521 gtcttgtgac gaattggagc tatttcaagc ccatcaactg ctggtggcac tgcaacgcct
    17581 gagatttcat gtaattgagc caaggcttca aagtctgtca aacctgcttt tccagttaca
    17641 gcttctactg caactactgg gaacttgtat ggactagctg ttgaagcaat cactgtctta
    17701 gttacatctc cagtaaccgc ttggtatttt ctataaactg ctgaggcaac cgccgtatgt
    17761 ggatcctcaa tataagaatc tgactcataa acacgcttga tttctgccgc tgtttcttcc
    17821 tcagtcgcat attcagctgc aaagaggtcc aaaatctctg catcaaagtc tgtcaactta
    17881 tattgtcctt gcgtgttcaa ggcattcata agttcagctg tcttttcagc attatttccc
    17941 aaaagatgga aaatcaagcg ctccaagttt gaagatacca agatatccat agatgggctg
    18001 gttgttacct taaactcacg ttttttgtca tagacacgtg ttttaaagaa gtctgtcaag
    18061 acattattgt catttgaagc acagattagc ttgccaactg gtaggccgat ttgtttggca
    18121 taaaaggcag ccaagatatt tccaaagttt cctgttggta ctgtgaagtt aaccttttca
    18181 ccagctacaa tttcaccagt cttaaccaat tgagcgtaag cataaacata ataaacaatt
    18241 tgtggcacca gacgaccaat gttcatagag ttagctgatg aaaattgcaa cttgttggta
    18301 gtcaattttt cacgaagagc cacgtcgtta aacatgtgct tcacatttgt ttgcgcatcg
    18361 tcaaaattac catcaatagc aataacatga gtattgtcac cattctgagt ggtcatttgc
    18421 aactcttgta ccttgctgac accacccttt ggataaaaga cgataatctc agtaccaggc
    18481 acatccgcaa accccgccat agcagctttc cccgtgtcac cagatgtcgc tgtcaagata
    18541 acaatcttgt tctccaaacc atgtttctta gcagcagtcg tcataaagta tggcaaaata
    18601 gacaaggcca tatccttaaa ggcaatcgtt gaaccatgga aaagttccaa attgtattgc
    18661 ccatctaatt tcactaatgg tgcaatagct ggagtatcaa atttgctatc gtaggcattg
    18721 ttgatacagt agtccaactc ctcagctgta aagtcatcta aaaatgctga caaaactagc
    18781 ttagcaactt cctggtaaga agcatctttc aatttgtcaa agtccaaatc tacctttgga
    18841 taagtaaccg gtgtaaacaa accgccgtcc gtcgccaaac cttgcaaaat tgcttggctg
    18901 gcagttactg tattgttggc atcacgcgtt gattgataaa ctaatgtcat tactctctat
    18961 cctttatcta tagtctcgtc cattatatca tgatttttca gaaaattctc cctttataag
    19021 agaaattata ggctcaattc ttctctcaaa ggctgtaaat aggtcatttc ttccttattt
    19081 ctcaccacta gtccctcctc agctagtagg agtaagtctt tggaaaattc aataatcgta
    19141 gtttcttcct catctgtaag atttttctta gaaaattgtc tccttaaaga cttgtaatca
    19201 taaccaaata ctttaaagaa aggtgctgtt tctaagtaag cttctaactt gtctaaatta
    19261 accaataatc ccaagtgaaa agctgcagaa gcaaaagtcc tatcaagtgg ctgtgtacac
    19321 acactacgaa actcaactgt tcctcgagtc gttaaatctt ggtactggta actacgatga
    19381 gtttcaaaat ccttctcttg ggggtaaata ataacctcat ccccattcag agcaaatgct
    19441 tggatttcgg acgtagccaa atagtcccca gcctgaatag gataaaaata ataggtctgc
    19501 ccatcacgtt ccgcagtaaa aatcgcagaa tgatttagat agtcaaaaaa atcagcttca
    19561 tcattaagga gtctagcatt gaccccaaca ttctctggat agataccatg catagattct
    19621 tcccagaaaa tatcccttga aattttcgta tcccaatccg cacccgaaaa ttcagagttt
    19681 gcaaataaat aagccttagc cgcttcaatt tgagtaaaag cattaatcac ccgtaagtag
    19741 ttggtttttg aaatatccag ctgaacctgg ctcccacaga taaaagtacc atattcaggg
    19801 aaatgatgta aatctgattt aataatattt ctactcaaat tcaaataatc catcaacatc
    19861 tgatagcgtg gataagccac tggacaattc tcatttttat cccagttggg atggatacca
    19921 cagccaacaa tagcatgatt tgattcagct aactttctct gaattacatt catataatta
    19981 ttgaaacgat tttcgacctc ttgaatcgtt tcagccttac caaatgcaaa ctcaatcgtt
    20041 gtataggaaa cttcaaataa aatagcatcc tgacttatcg gatctactaa ctggatcaga
    20101 ttgccaaaat catctacctt tgctacggtg agatccaaag tagaaactaa ataatgaaat
    20161 agatccttta taacttcaac atctgtagca tccccttcta aacttgcaac aggatactcc
    20221 aactcaattc cgacaaacaa ttcaggattt tctttaatat ttttcaaata ccgatgtttt
    20281 aataaatcga tagaacaaga catactaccc tacactttct taatctaaat aaaatttgaa
    20341 taactataat tataccaaaa ataatataaa aaaggaacga agaataacaa cgttcctaac
    20401 actatactat accggcggcc ggggtcgaac cggcacgtcc ttgcggacac tggattttga
    20461 gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt aactggggta gctggattcg
    20521 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataata
    20581 taaaataggc gagtgatggg gatcgaaccc acgcatgcca gagccacaat ctggtgtgtt
    20641 aaccacttca ccacacccgc cataattcta ttaacacggg cagtaggaat tgaacccaca
    20701 ctgaaggttt tggagacctt agttctacct ttaaactatg cccgtaaaat ggaaggggag
    20761 ggattcgaac ccccgaaccc gaaggagcgg atttacagtc cgccgcgttt agcctcttcg
    20821 ctacccttcc aaaatata
//
LOCUS       DAVAZV010000040        20780 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVAZV010000040 DAVAZV010000000
VERSION     DAVAZV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20780
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.040"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            398..1091
                     /locus_tag="VQT46_001418"
                     /pseudo
     CDS             398..1091
                     /locus_tag="VQT46_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809626.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            1147..1419
                     /locus_tag="VQT46_001419"
     CDS             1147..1419
                     /locus_tag="VQT46_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="HET2371434.1"
                     /translation="MFLLFSALVGMLSQLKEVPESVFLQETVEENHLVNVYSVLEVIS
                     TLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK"
     gene            1733..1864
                     /locus_tag="VQT46_001420"
     CDS             1733..1864
                     /locus_tag="VQT46_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET2371435.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            1885..3435
                     /gene="dltA"
                     /locus_tag="VQT46_001421"
     CDS             1885..3435
                     /gene="dltA"
                     /locus_tag="VQT46_001421"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET2371436.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFVQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMIMDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGVTHFYFDG
                     EELTVKTAQKLRKRFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3432..4676
                     /gene="dltB"
                     /locus_tag="VQT46_001422"
     CDS             3432..4676
                     /gene="dltB"
                     /locus_tag="VQT46_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET2371437.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4690..4929
                     /gene="dltC"
                     /locus_tag="VQT46_001423"
     CDS             4690..4929
                     /gene="dltC"
                     /locus_tag="VQT46_001423"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET2371438.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            4922..6190
                     /gene="dltD"
                     /locus_tag="VQT46_001424"
     CDS             4922..6190
                     /gene="dltD"
                     /locus_tag="VQT46_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET2371439.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6345..6785
                     /gene="adcR"
                     /locus_tag="VQT46_001425"
     CDS             6345..6785
                     /gene="adcR"
                     /locus_tag="VQT46_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET2371440.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6785..7489
                     /locus_tag="VQT46_001426"
     CDS             6785..7489
                     /locus_tag="VQT46_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET2371441.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNTHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7482..8288
                     /locus_tag="VQT46_001427"
     CDS             7482..8288
                     /locus_tag="VQT46_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET2371442.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGRSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8298..9803
                     /gene="adcA"
                     /locus_tag="VQT46_001428"
     CDS             8298..9803
                     /gene="adcA"
                     /locus_tag="VQT46_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET2371443.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKVTFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(10923..11696)
                     /locus_tag="VQT46_001429"
     CDS             complement(10923..11696)
                     /locus_tag="VQT46_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2371444.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            11872..13275
                     /locus_tag="VQT46_001430"
     CDS             11872..13275
                     /locus_tag="VQT46_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET2371445.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            13390..14028
                     /locus_tag="VQT46_001431"
     CDS             13390..14028
                     /locus_tag="VQT46_001431"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET2371446.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            14040..14480
                     /locus_tag="VQT46_001432"
     CDS             14040..14480
                     /locus_tag="VQT46_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET2371447.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            14473..14904
                     /locus_tag="VQT46_001433"
     CDS             14473..14904
                     /locus_tag="VQT46_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2371448.1"
                     /translation="MFNRGILVASHGDFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVDELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISNYDSKINLEEIVHNAQNSLFNVKQQLNVEEEENLCL"
     gene            14895..15365
                     /locus_tag="VQT46_001434"
     CDS             14895..15365
                     /locus_tag="VQT46_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET2371449.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            15390..16163
                     /locus_tag="VQT46_001435"
     CDS             15390..16163
                     /locus_tag="VQT46_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2371450.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            16160..16960
                     /locus_tag="VQT46_001436"
     CDS             16160..16960
                     /locus_tag="VQT46_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2371451.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            17019..19313
                     /locus_tag="VQT46_001437"
     CDS             17019..19313
                     /locus_tag="VQT46_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET2371452.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            19323..>20780
                     /locus_tag="VQT46_001438"
     CDS             19323..>20780
                     /locus_tag="VQT46_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371453.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLH"
BASE COUNT         6450 a         3391 c         4377 g         6562 t
ORIGIN      
        1 ctactcgatt aactcccctg aaatttgttt taattatgca aatttcacgt atttttgatg
       61 ctgagacgac gatcctggga acttttcaga tatttttttg actatctaaa atctatcatt
      121 agaaaagctt agagcgccaa aggatttgag cgtttttctg atttttaaga ctttttccca
      181 gtctcttttt cgattgaaga tgtaattatt ctactaacta acttcttagt actagccaac
      241 aacgataatc ataattcctc ctaaaattag gaataataaa ggcaatagtt tttgtttttt
      301 catgtaaaaa acctcacttt tgttttctgc tattttatgc taaaatatta aaaatcaaat
      361 ttaattccaa agtttgtaac taaaggggga gcgctacatg tctaattcat ttgtcaagtt
      421 gttagtctct caattatttg caaatttagc agatattttc tttagagtaa caatcattgc
      481 taacatatac attatttcaa aatcagtaat tgccacatca ctagttccta tcttaatagg
      541 aatatcctct tttgttgcga gtcttttagt tccgttggtt actaaaaggt tagcgctaaa
      601 tagggtttta tctttatctc aatttggaaa gactatatta ttggcgatac tggtaggaat
      661 gtttaccgta atgcaatccg tagcgccttt ggtgacctat ctatttgttg ttgcaatttc
      721 catactagat ggttttgcag cacccgtttc ctatgctatt gtgccacgct atgcgaccga
      781 tttgggtaag gctaattcag ccttatcaat gactggtgaa gctgttcaat tgataggttg
      841 gggattaggt ggactcttgt ttgcaacaat tggtctgtta cctaccacgt ttatcatttt
      901 agtcttgtat atcatttcta gctttctgat gttatttctt cctaacgctg aagtggaggt
      961 gttagagtca gaaactaatc ttgaaatttt gctcaaaggt tggaagttag ttgctagaaa
     1021 tcctagatta agactttttg tatcagcaaa tttattggaa attttttcaa atacgatttg
     1081 ggtttcttcc attttgtagc tatggcaata gtgacactga ctattctata ttttccaaac
     1141 gcacagatgt ttttattatt ttcagcttta gttggtatgt tatcgcaact aaaagaagtt
     1201 cctgaaagtg tatttcttca ggaaacagta gaggaaaatc atttagttaa tgtctattcc
     1261 gttcttgaag tgatttctac attagcattt tcagtatttg ttttgctaat gagctatatt
     1321 actgagagtt ttggtattag catcagtttt tggctatcag ccatttgtct gatgatagaa
     1381 gctattttaa tttatatcag acgagattat tttaaatgag agagtggtta aaaagtcttt
     1441 aaaaatcaga aaagcgcata gtatcaggtg ttgaaaaaac ttgatattgt gtgttttatt
     1501 atgggaagat ttacttcatt gtctcctgaa atggagtttt gaagcaggat cactctattt
     1561 gaaaatatac atagaaaaac tgtataatcc ttaaaataag ctgaaatcta ttggaaacat
     1621 acggtaaaca attgaaaagg tactatataa agtggtacaa tggtagaaaa ataagctagt
     1681 aagaatcact cttattttag cgaaaaatta cagaaatgaa tggtttttct tgatgaaaca
     1741 gagaaaagaa ttgtacctct ttcttggtcg gacagccttg tattttctta tctttctagg
     1801 gctgctttac ttctttagct atcttggtca gggtcaagga agctttatct ataatgaatt
     1861 ttaacttgaa ggagaatccc tattgtgtca aataaaccaa tagcagatat gattgaaacc
     1921 attgagcatt ttgctcagac acagcctagc tatcctgtct ataatgtttt ggggcaggaa
     1981 cacacttatg gcgatttaaa ggctgattcg gatagtttgg ctgcagtcat tgaccaacta
     2041 ggcttgcctg agaagtctcc tgtggttgtt tttggtggcc aagaatatga aatgttggca
     2101 acctttgtag cgctgactaa gtcaggtcat gcctacattc caattgatag ccattcggcc
     2161 ttggagcgag tttcagctat tttagaagta gcagagccaa gcttgattat tgccatttca
     2221 gcctttccct tggagcaggt ttctacacca atgataaatc tagctcaggt tcaagaagcc
     2281 tttgttcaag ggaataacta tgaaatcacg catccagtca agggagatga taattactac
     2341 attatcttta cttctggtac gactggtaag cctaagggag tgcagatttc acatgataat
     2401 ctcctcagct ttacaaactg gatgattatg gataaggaat ttgcgacacc gagtcgtccg
     2461 caaatgctgg cacagccacc ttattctttt gacttgtctg tcatgtattg ggcaccgacc
     2521 ttggcacttg gtggtacgct tttcactctt ccttcagtca tcactcagga ctttaagcaa
     2581 ctctttgcgg ctatcttttc attgccaatc gctatctgga catcaacacc atcctttgca
     2641 gatatggcca tgttgtctga atacttcaac agtgagaaaa tgcctggagt cacgcatttc
     2701 tactttgatg gtgaagaatt gacggtcaaa acagctcaaa aactgcgcaa gcgtttccca
     2761 aatgcccgta tcatcaatgc ttacggccca acagaagcga cagtagctct gtcagcagtt
     2821 gccgtgacag acgagatgtt agcgactctc aaacgcctac caatcggcta taccaaggct
     2881 gattctccaa cctttatcat tgacgaggaa ggaaataaac tgccaaatgg cgaacaggga
     2941 gaaatcattg tttctgggcc agctgtttca aaaggttata tgaacaatcc tgaaaaaaca
     3001 gcagaagcct tctttgagtt tgaaggtctg ccagcctatc acacaggcga tgtgggaacc
     3061 atgacagatg agggcttgct tctctacggc ggacgcatgg acttccagat taagtttaac
     3121 ggttaccgca ttgagttaga agatgtctct caaaacctca acaagtctcg ctttatcgaa
     3181 tctgctgtcg cagtaccgcg ctataacaag gaccacaagg tacaaaatct attggcttat
     3241 gtcatcttaa aagacggtgt tcgtgagcag tttgagcgag atatcgatat taccaaggcc
     3301 atcaaggaag acctgacaga catcatgatg tcctatatga tgccatctaa attcctttac
     3361 cgagacagtt tgccactgac tccaaatgga aagattgaca tcaaaggatt gattaacgag
     3421 gtgaataaga gatgatggag ttttttcaac agcttcctca tttagagcca tatggcaatc
     3481 ctcagtattt tgtttatgtg attgctgcaa ccttgcccat ctttataggt ctctttttca
     3541 agaaacgctt tgcctggtat gaagtgttgg taagtctctt ctttattgtc accatgttgg
     3601 tgggtggaaa gaccaatcaa ctagctgcct tgggtattta cctttgctgg gaaatattgc
     3661 tcctgctttt ctacaagcat tatcgaaaaa gcaaggatgg caagtgggtc ttctacttag
     3721 ttagttttct gtccctactt ccgattatct ttgtcaaggt gcaaccagct atcaatggaa
     3781 cgcagtcttt gcttgggttc ttgggaattt cttatcttac ctttcgttcg gttgggatta
     3841 tcatcgagct gagagatgga gtgattaagg attttaccct ctgggaattc ctccgtttcc
     3901 ttctcttcat gccaactttc tcgagtggtc caatcgatcg ctttaagcga tttaatgaaa
     3961 attatcaggc tattcctgag cgagatgagt tgatggatat gctggatgaa tctgtccgct
     4021 atatcatgtg gggctttttg tataagttta tcctagctca tgttttagga gagaccttac
     4081 tacctcctct gaagaattta gccttgcagt caggtggctt ctttaatctc tatgccttgg
     4141 cagttatgta tacttttggt ctggagctct tctttgactt tgcaggttat tctatgtttg
     4201 ctttggccat ctcaaacttg atgggaatcc gtagccctat caactttaac aagccctttt
     4261 tatcaaggga tttaaaggag ttttggaatc gctggcatat gagtctgtcc ttctggttcc
     4321 gtgactttgt ctttatgcga atggtgatgg tgttaaccag aaagaaagtc tttaaaaatc
     4381 gtaatgtaac ctcaagcatg gcctacattg taaatatgct gattatggga ttttggcatg
     4441 gtgtgacctg gtactatatc gcctatggac tctttcatgg actaggcttg gtcatcaatg
     4501 atgcctgggt tcgcaagaaa aaaacactca ataaggaacg gaaaaaagca gggaaggctg
     4561 ccctacctga gaatcgctgg attcagttgc ttggcatggt tgtcactttc catgttgtca
     4621 tgttgtcatt cttaatcttt tctggattct tgaataatct atggtttaaa aaataaaagg
     4681 aaataaaata tggatatcaa atcagaagtt atcgaaatta ttgatgagtt gtttatggaa
     4741 gatgtttctg acatgatgga tgaagatctt tttgatgcag gtgtcttgga tagtatggga
     4801 acggttgagt tgattgtgga gattgagaac cgttttgaca ttcgtgtccc tgtaacagag
     4861 tttggtcgtg acgactggaa tacagctaat aaaatcatag ctggtattgt ggagctacaa
     4921 aatgcttaaa cgcttatgga tgatcttcgg accggtcttg atcgctggtt tgttggtttt
     4981 tctgctcatt ttcttttatc ctactgagat gcatcataat ctaggagctg aaaagcgttc
     5041 agcagtggct actactatcg atagttttaa ggagcgaagt caaaaagtca gagcactatc
     5101 tgatccaaat gtgcgttttg ttcccttctt tggctctagt gaatggcttc gttttgacgg
     5161 tgctcatcct gcggtattag ctgagaaata caatcgttcc taccgtcctt atcttttagg
     5221 acagggggga gctgcatcgc ttaaccaata ttttggaatg caacagatgt taccacagct
     5281 ggagaataaa caagttgtgt atgttatctc acctcagtgg ttcagtaaaa atggctatga
     5341 tccagcagcc ttccagcagt attttaatgg agaccagttg actagttttc tgaaacatca
     5401 atctggggat caggctagtc aatatgcagc gactcgctta ctgcaacagt tcccaaacgt
     5461 agctatgaag gacctggttc agaagttggc aagtaaagaa gaattgtcga cagcagacaa
     5521 tgaaatgatt gaattattgg ctcgttttaa tgaacgccaa gcttcctttt ttggtcagtt
     5581 ttcggttaga ggctatgtta actacgataa gcatgtagct aagtatttaa aaatcttgcc
     5641 agaccagttt tcttatcagg caatagaaga tgttgtcaaa gcagatgctg aaaaaaatac
     5701 ttccaataat gagatgggaa tggaaaatta tttctataat gagcagatca agaaggattt
     5761 gaagaaatta aaggattctc agaaaagctt tacctatctc aagtcgccag agtataatga
     5821 cttgcagttg gttttaacac agttttctaa atctaaggta aacccgattt ttatcattcc
     5881 acctgttaat aaaaaatgga tggactatgc tggtctacga gaggatatgt accaacaaac
     5941 ggtgcagaag attcgctacc agttagaaag tcaaggtttt accaatatag cagatttttc
     6001 taaggacggc ggggagcctt tctttatgaa ggacaccatt caccttggtt ggttgggttg
     6061 gttggctttt gacaaggcag ttgatccttt cctatccaat cccacaccag ctccgactta
     6121 ccatctgaat gagcgctttt tcagcaaaga ttgggcgact tatgatggag atgtcaaaga
     6181 atttcaatag ataatataat atagaagagt tcaagaatga aactagtttt cacgtttttt
     6241 cttgactctt tttttgcttg tgatataatt aactggtaaa caaaatgtca aagaatagta
     6301 tttttctctt aaaaaagaga agtctaaaag gaaaggagtc agatatgaga cagctagcaa
     6361 aggatatcaa tgcttttttg aatgaggtga ttttgcaggc ggaaaatcag catgaaatcc
     6421 taataggtca ttgcactagc gaggtggccc tgaccaatac tcaggagcat atccttatgc
     6481 tcttgtcaga ggaatcttta acaaattcag aattggcccg tcgtctcaat gtcagtcagg
     6541 cggcagttac caaggccatt aagtctttgg tcaaggaagg gatgttggaa acatctaaag
     6601 attctaaaga tgcgcgtgtg attttttatc agttgactga cttggctcgt ccaatcgctg
     6661 aggagcacca ccatcaccat gagcatacac ttttaaccta tgaacaagtg gcgactcagt
     6721 ttactccaaa tgaacaaaaa gtgattcagc ggtttttgac tgctttagta ggagaaatca
     6781 aataatgaga tatattacgg tagaggattt gtccttctat tatgataagg aacctgttct
     6841 tgaacatatc aattattgtg ttgatagtgg ggaatttgtt accttgactg gggaaaatgg
     6901 agcggctaag acgacgctca tcaaggccag tcttggaatt ctgcaaccac gcattggaaa
     6961 ggtggctatt tcaaagacaa atacgcaagg taagaaattg agaatagcct atcttcctca
     7021 acaaattgcc agttttaatg ctggttttcc aagtacggtc tatgaatttg tcaagtcggg
     7081 tcgctatccg agaaaaggct ggttccgtcg tttgaatact catgatgagg agcatatcaa
     7141 ggctagtctg gactcagttg gcatgtggga acatcgagac aaacgcttgg ggtctctatc
     7201 tgggggacaa aagcagcgag cggtaattgc gcgtatgttt gcttctgacc ctgatgtgtt
     7261 tatcctagac gagccgacaa cggggatgga tgcaggaagt aaaaatgaat tttacgaact
     7321 catgcaccac agcgcccatc atcatggcaa ggctgttttg atgattaccc atgaccctga
     7381 agaagttaag gattatgcgg atcgcaatat tcatctagtc cgtaaccaag actcgccatg
     7441 gcgttgtttc aacgttcatg agaatgggca ggaggtgggc catgcttagt ttattatctt
     7501 acgactttat acaacgcgcc tttttggcgg ttattgctat gagtcttttc tcaccggtat
     7561 tgggaacctt cctcatcttg cgtcgtcaga gtttgatgag tgataccctt agccacgtct
     7621 cactttcagg tgtagccttt ggtctggttt tggggatttc tccaactgtt tctactattg
     7681 ccattgtctt gattgcggcg gtctttctgg agtatctccg tacggtttac aagagcttta
     7741 tggaaatcgg gacagctatc ctcatgtcaa caggtttggc tgtttctctg attgtcatga
     7801 gcaagggtag aagctcgagt tcaatgagtt tggaccaata tctctttggt tcgatcgtga
     7861 ctatcagtga agaacaggtc atttccctct ttgtcattgc ggcggttgtt ttgattttga
     7921 cctttctctt tcttcgtcct atgtatatct taacttttga cgaagatacg gcctttgtgg
     7981 atggcttgcc agttcgtacc atgtccattc tttttaacat ggtgacaggg gtggctattg
     8041 cccttatgat tcctgcagca ggagctcttc tggtatcgac cattatggtc ttgccagcta
     8101 gtattgccct gcgtctgggg aaaaacttta aatcggttat gctgcttgcc agtgcgattg
     8161 gctttttggg aatggtagca ggactttaca tttcctacta tgcagaaaca cctgcaagtg
     8221 caagtattac cattattttt gtaactgtct ttatactaat cagtttagta agacgtttta
     8281 tcaaatagga gacgaacgtg aaaaaaatta gcttattact agccagtcta tgtgccttgt
     8341 ttttagtggc ttgttccaat caaaaacagg cagatggtaa actcaatatc gtgacaacct
     8401 tttaccctgt ctatgaattt accaagcaag tcgcaggaga tacggctaat gtagaactcc
     8461 taatcggtgc tgggacagaa cctcatgaat acgaaccatc tgccaaggca gttgccaaaa
     8521 tccaagatgc agataccttc gtttatgaaa atgaaaacat ggaaacatgg gtacctaaat
     8581 tgctagatac cttggataag aaaaaagtga aaaccatcaa ggcgacaggc gatatgttgc
     8641 tcttgccagg tggcgaggaa gaagagggag accatgacca tggagaagaa ggtcatcacc
     8701 atgagtttga cccccatgtt tggttatcac cagttcgtgc cattaaacta gtagagcaca
     8761 tccgcgacag cttgtcagca gattatcctg ataaaaaagt gacctttgag aagaatgcag
     8821 ctgcctatat cgaaaaattg caagccttgg ataaggctta cgcagaaggc ttgtctcaag
     8881 caaaacaaaa gagctttgtg actcaacacg cagcctttaa ctatcttgcc ttggactatg
     8941 gactcaaaca agtcgcaatc tcaggacttt ctccagatgc agagccatca gctgctcgct
     9001 tggcagaatt gacagagtat gtcaagaaaa ataaaatcgc ctatatctat tttgaagaaa
     9061 atgcctcaca agcccttgct aacacacttt caaaagaagc aggtgtcaaa actgatgtcc
     9121 tcaatccttt agaaagtctg acagaagagg acaccaaggc tggagaaaac tacatttccg
     9181 tgatggagaa aaacctcaag gctttgaaac aaacaacaga ccaagaaggc ccagcaatcg
     9241 aacctgaaaa ggcagaggat accaagacag tccaaaatgg ttacttcgag gatgcagctg
     9301 tcaaggaccg caccttgagt gactatgcag gtaactggca atcagtttat cctttccttg
     9361 aagacggcac gtttgaccaa gtctttgact acaaggctaa gttgactggt aagatgaccc
     9421 aggctgagta caaggcttac tatacaaaag gctatcagac agatgtgact aagattaaca
     9481 ttactgataa tactatggaa tttgttcaag gtggacaaag caagaaatac acttacaagt
     9541 atgtcggtaa gaaaattttg acttacaaga aaggcaatcg tggcgtgcgt ttcctctttg
     9601 aagccacaga tgctgacgct ggacaattca agtatgttca gtttagtgat cacaatgttg
     9661 ccccagttaa ggcagaacat ttccatatct tctttggagg cacaagccaa gaagccctct
     9721 ttgaagaaat ggacaactgg ccaacctact acccagataa cctatctggc caagaaatcg
     9781 cccaagaaat gttggcgcat tgatgagaaa tcgactagtt cataagagct agtcggtttt
     9841 ttgatactag atggctaact tcattataga cctttcagaa ctttaaacaa taaataaaac
     9901 tcttgaaata tctgggctta tatgctagaa tgtagttagt gtataaggtt cattagaaca
     9961 ccaaagcccc taactagtgc catagttaag ggcttttttg acgtatctta gcgatttaac
    10021 gggtgtttat aggctagtca gtcggtctac ttcttaccat ctagccattt gcagacgaaa
    10081 tacaagataa ttccagctat aacatctgct ataatagtaa gagcaagctc tggtataagg
    10141 ctcattagtt tcacctcctc tcacgaaccc ataggaacgt aatcggtaac cgatgacaaa
    10201 aatagtatac cacactaaat ttagatcatc aacctcactt aatgcttgaa ctattgtaga
    10261 ttatatgcta aaatgtagtt aattgataag gttcattaga acaccaaagc ccctaactat
    10321 ggccgtagtt aagggctttt ttgacgtatc ttagcgattt aacgggtgtt tataggctag
    10381 tcactcggtc tactccttac tatctagcca tctgcagacg aaatacaaga taattccagc
    10441 tataacatcc gctataatag taagagcgag ctctatgata aggctcatta gtttcacctc
    10501 ctctcacgaa cccataggaa cgtaatcggt aaccgatgac aaaaatagta taccacaata
    10561 tatttagatc atcaaggtca cttaattctt gaaatatagg gtctaggcga caaagtcttt
    10621 aaaatcagaa aaacgcataa tatcaggtgt gcaaaaactt gatactatgc gttttattgt
    10681 gggaaggttt actccatttt ctcctgaaat tgagtttttg tccagcctct gtttttagaa
    10741 ttgctaagaa aataatgtca tgtggtgaat atttgtaaat cagtcagcag acagaacgaa
    10801 tactcttcga aaatctcttc acatcatgtc agcttcgtct tgccgtgtcc atgggggact
    10861 tgacttgatc agttttcaaa tctgtacttt gagcaagctg agactagctt cctatttgat
    10921 tttcattgaa tatcagaaac ccattctcca tcaaataatt cgactgcgtc taataatttt
    10981 tggtctggca aggtgtcaga aataaaggtt gtgtatttgg agaggggatt aattttaaaa
    11041 aatccagtct tgtaaaattt agaactatca atcagtaaga tggtttcatg ggctttgtca
    11101 ataatattct tttttgaaat agcttggctg agagaagctt cataaacata ttggtcatca
    11161 atacctcttg ctgaacaaaa tgctaaatcg atattaaaat gatctaataa agaattttcc
    11221 ttatcatagt tgaccacgga acaggattga tgtttgacct cgccagatgt gataaagatt
    11281 ttggagctat ctttaacagt ttcagatagg gtttgtgcag tatgtaaacc atttgtaaaa
    11341 ataatcaaat tatcaagttc agaaagatag ggacaaagtt cgtagacagt agtactagaa
    11401 tctagataga tacacatacc agaccgaata aagtctttag cgagactagc gattagtctt
    11461 ttttgcctag tactttctcc ttcccgtatt tgatgagaaa gttcaattgt gttcatagag
    11521 gacagggtca cgtatccgtg ctttcttttg ataagacctt gattttctaa gaaaattaaa
    11581 tcacgacgta aggtacttgt gctggagaaa gtgatttctg ccagctcttt tacggcaatt
    11641 ctttttttct ttttaataat ttcaatcaat tcaagtacac gttcatcttt tatcataagc
    11701 tcctcctaat ttatcatttc aactatatta tagcacaaat tggaggaatt tgaattattt
    11761 ttatgaatat tgggttaaca tttgaacatt attcaagtaa gcgttcacat attgaaaaaa
    11821 taaaacgtgg ggattataat aaagttaatc aaggacgaag agagaagaaa aatggaagcg
    11881 gttttagcaa tagatttagg tgcgacttct ggaagagcaa tcgttggtta cctttctgaa
    11941 aataaactag taatggaaga aataaatcgc ttttctaatc tacctattag agtaaaaggg
    12001 catttatctt gggatattga ctttctacta gctaaaattc ttgaaagtat ccgcttggct
    12061 aatactagtt acaagatttt atctatcggt attgacacat ggggagttga ttttggactg
    12121 attgataatg aaggtaagct gttatcacaa cctgttcatt atcgtgatga aagaacaaag
    12181 ggagtgttaa aggaaatatc tgaaatgact gaattagaaa aactgtattc agagacagga
    12241 aatcagatta tggagataaa taccttgttt caactcttta aggcacgtca agaatctcct
    12301 gactctttct ataagaccaa taagattctt ttaatgccag atttgtttaa ttatctcttg
    12361 acaggtaagt ttgctacaga aaaaagcatt gcttcaacaa ctcaattatt tgatcctagg
    12421 agtcaaaatt ggaatcagaa tatcttaaaa ctatttgaat tggattcatc tttacttcct
    12481 gaaattgttt cagagggaaa tgttcttgga aggataaaaa aggagtatgg tttaggcgat
    12541 attcctgttg tgaatgtttg tagtcatgat acagcaagtg cgattgtctc agtacctaag
    12601 acagaaggta gtttatttat ttcatcaggt acttggtctt tggttggagt ggaacttact
    12661 tcaccgattc ttactaccga atccttcagt tatggattta caaatgaagt cggtaaagat
    12721 ggagtgatta catttctgaa gaattgtaca gggttgtgga tcatagagga actaagacgt
    12781 tcatttgaac gaagagggaa agcctattct tttgatgata ttaggacaat ggtggagaaa
    12841 gaaaaagaaa atcttcctct gattgatact gaatcaactg aatttgcaac agaatctgat
    12901 atgcacaaga ctttgacaga atatctagct tatcatcatg aaactagaga gtggacagat
    12961 ggacaactat ttaagattgt ttatgaaagc ctagctgaaa cgtataggaa agcgatagag
    13021 ttattagaag aactaactca taaggtttat aagaggatat atgtgattgg aggaggtgct
    13081 agagccagtt attttaacca aatgattgct gatagaactg gtaaagaggt tcttacaggt
    13141 ttgactgagg ctacagctgt ggggaatatt gttgtgcagc tcatagctat gggacaatta
    13201 aaagggatgg aagaggctca ccatgttatt gaggagtttc tacaattaga gagttattac
    13261 tcccaaaaga attaaaaaga ttgagagttt gtaaatttgc ctccctcccc cttcttagct
    13321 tttgtgcagg aaggggggat aattggtgaa ttgaaaaata tttagtgttt tgatatgagg
    13381 aggacaagga tgtcagatgt aaaacaagaa ttaattaaat atggtaagaa gctagtagaa
    13441 acagatttga cgaaaggaac aggtgggaat ctcagcgttt tcgatcgtga aaaacaattg
    13501 atggcaatta ccccgtcggg tattgatttc tttgaaatca aagaatccga tattgtagtg
    13561 atggatatta atggaaatgt tgtagaggga gaacgcttgc catctagcga atggtatatg
    13621 catttgattc aatatcaaac tcgtgatgat atcgatgcaa ttatccatgc tcatacaact
    13681 tatgcaacag tattagcttg tctcagagaa ccacttccag cgagtcatta tatgattgca
    13741 gtggcaggga aagatgttcg ggtagctgag tatgcaacat atggcacgaa agaattggct
    13801 gtgaatgcag ctaaagcaat ggaaggtcgt agagcagttt tactagcgaa tcatggaatt
    13861 ttagcaggtg cacaaaattt attgaatgca tttaatattg ttgaagaagt tgaatattgt
    13921 gcaaaaattt attgtttagc taagaatttt ggagagccag tagttcttcc tgatgaggag
    13981 atggaattga tggcagaaaa atttaaaaca tacggtcaga gaaaataggg aggatattaa
    14041 tgttaaaaca tataccgaaa aatatttctc cagatttatt gaagacttta atggaaatgg
    14101 gacatggaga tgaaatagta ttagctgacg cgaattatcc ttctgcctca tgtgcaaata
    14161 agctaattcg ttgtgatggc gtaaatattc cagaattatt agattccatt ctgtatttaa
    14221 tgccattaga tagttacgtc gatagttcaa ttcagtttat gaacgttgtt tcgggtgatg
    14281 atattcctaa gatatggggt acctatagac agatgattga aggtcatggt acagatctta
    14341 aaacgattac ttatcttaga agagaagact tttatgaacg tagtaagaaa gcttatgcta
    14401 ttgttgctac aggagaaact tcactttatg ctaatattat ccttaagaaa ggagtagttg
    14461 ttgaaagaga aaatgtttaa tagaggaatt ttagttgcca gtcatggtga ttttgctagc
    14521 ggagctctca tgaccgcaga aatgtttgtt ggtgagacaa caaatgatag agttaggaca
    14581 ttaggtttga tgcctggaga gaatattgta gagtttgagc attattttaa aaatcaagtg
    14641 gatgaactgt tagactcaaa tcaagaggtt atcgttttga ctgacttgat tggaggaagt
    14701 cctaataatg tggctttgtc acggttttta aatttggatt cagttgatat tgtaacaggg
    14761 tttaatattc ctctcctagt ggaattaata tcaaattatg attcaaaaat caatttagaa
    14821 gaaattgttc acaatgctca aaatagtttg tttaatgtta aacaacaact taacgtagag
    14881 gaggaagaaa atttatgtct atagagtttg ttcgtattga tgaccgtctg gtacatggtc
    14941 aagttgtcac tacgtggcta aaaaagtatg atattgagca agttatcatt gttaatgatc
    15001 gcatctcaga agataaaaca cgacaatcta ttttaaagat ttctgcacca gtaggtttaa
    15061 aaattgtttt ctttagtgta aaacggtttg tggaagtttt aaactctgtg ccaataaaaa
    15121 agagaacaat gctgatatat acaaatccaa aagatgtgta tgattctatt gaaggaaatt
    15181 taaaattgga gtacctcaat gtaggacaga tgagtaaaac ggaggaaaat gaaaaggtaa
    15241 cgggaggtgt agctctaggt gaagaagaca aatattattt taagaaaata gttgataagg
    15301 gaacgagagt tgaaattcaa atggttccta atgataaagt tacaatgttg gaaaaatttt
    15361 tataaaaata atttaaggag gtacagtata tgctattcac acaagcatta ctggtgacat
    15421 tagttgggat tattgccact attgactata atggaccgtt atttatgatt caccgtccgt
    15481 tagttacaag tgcaatggtt ggcttagtct taggagattt cacccaaggt gttcttattg
    15541 gttcagctct tgaattaact tggctcggtg taacaggtat tggaggttac actccaccag
    15601 atactatttc aggtgcgatt attggtactg catttggtat tttatctggt caaggagaaa
    15661 ctgctggtat cgctatagca gttccaattg cagttgctac ccaacagttg gatgttcttg
    15721 caaaaacttt agatgtttat tttgtgaaaa aagctgataa tgatgctaaa aacggagatt
    15781 attcaaagat cggtttttat cattattcaa gtttggtttt aatcacgtta tttaaaattg
    15841 taccaatttt cctagctatt atgcttggag gggaatatgt ggcagacttg tttgctaagg
    15901 ttccaccaat cgttatgcag ggacttaact ctgcaggtgc tttactacct tcaattggtt
    15961 ttggtatgct tttaaatatg atgctcaaga aaaatatgtg ggtattcttg ttgattggat
    16021 tcatttgttc tgtgtatgga ggaatgtcaa ccattgggat ctcactagtt ggtattgcgg
    16081 tagcatactt ctacgatatg attggaagta aaccacaaga aacaacttca agtagtgatg
    16141 ttgaggagga tcttgatcta tgatgaataa taaagtaact aaagttgaac ttaaaaaagt
    16201 tttcaaacga agttttatgt atggttcttc atggaactat gagagaatgc agaacctagg
    16261 ttttctatat acaattcttc cagtattgaa aaaactatac ccagacaaag attcagcttc
    16321 tcctgcaatg aaacgtcacc ttgagttttt caatactcat caaacagcgg caccatttat
    16381 tcttggagtt acttccgcta tggaagaaca agaaggaaat gaaggtgcag cttcaattac
    16441 tggtattaaa gttggcttga tggggccact ggctggtcta ggagatagtt tgttctggct
    16501 gacactagtt cctatctgtt ttagtattgg tgcgtcttat tctaaagacg gcggtgcttt
    16561 aggtatcttt atcgccttaa tattgtttaa tattattaat attcctgtta aatatttcgg
    16621 tttgaaatat gggtatacta agggttctag tcttatccaa gaaaataata caaaaggaac
    16681 attgaatcgc gttacgagta tggcgacagc attagggcta gtactagtgg gtggtttgat
    16741 tccatcaatg gttggtatta attttggatt agaatttaag cagggggaac ttgttatttc
    16801 tgttcaagaa atgattacaa aattaattcc aggatttatc cctatggctt tgactttatt
    16861 aatgtgtaaa ttaattagaa aaggaaagaa tccggttgta ctaatcttta gtgttatggc
    16921 tattggagtt atcctagttg ttttaggaat tttgaagtag tagaaagtgt ggaggtggta
    16981 tttgggatat cacctccatt ttggaagaga ggtaaagagt gaaattatgg tataagaaag
    17041 ctgcctcaaa ttggaatgaa gccttgccga ttgggaacgg tcatttaggt ggtatgattt
    17101 atggttcagc tacaaaagaa tgtattcaac taaacgatga gactatttgg tatagaggaa
    17161 agtcagatag aaataatcca gactcactat tgcatcttaa aaaaattcgg gaatatcttt
    17221 tagatggaga aattcagaaa gccgaagaat tgataaagtt aacaatgttt gctaccccaa
    17281 gagatcaaag ccactatgaa ttacttgggg aactttacat tgagcatata gatattcagt
    17341 cttgtgctct ttcattgtat gaaagagagc tagatttaga tacagctatt tctaatgttg
    17401 tgtttgagcc taatagttgt aatttacaaa taaaaagaga atattttacg agttttaata
    17461 agaatatttt atgttgccgt atagtgtcat cagttcaaaa cacattaaat ttaaacatta
    17521 atttgggtag aaataaacgg tttaatgacg aagtatctaa actggattca agtacaattt
    17581 taatgtcggc ctctgctgga ggtagaaaag gtgttcagtt taaagtagta tgtcattcta
    17641 aagttacgga tggtgaagta agtgtattgg gagagacaat agttattcgg aatgctacag
    17701 aggtatttct ttatctcaaa tcaatgacgg attattgggg aaatatagat atttcttctc
    17761 ttcagggaga atttagtagt attgattact ttacagaaaa agatgaacat gtaaaaaaat
    17821 atcaggagca atttaataga gttgatttta aactagacta tagtaaagat tgtcttagca
    17881 ttccaacgaa tctacttctt gaaaacacta aaaagtatag taactacttg actaacttgt
    17941 tatttcatta tggaagatat ctgttaatat cgtctagtca accgaatggt ttacctgtca
    18001 atcttcaagg aatatggtgt gatgaattaa atccaatttg gggttctaaa tatacgatta
    18061 atattaatac tcaaatgaat tattggatgg taggtccatg tgatttacca gaagtagaat
    18121 atccattatt tgatatgctc gaaagaatga gagaaccggg aagactaacc gctaagaaaa
    18181 tgtatggagc tagaggtttt acagcacatc ataatacgga tggttttggc gatacggctc
    18241 cccaatctca tgccatgggg gctgcaattt gggtattaac tattccatgg ttatgtactc
    18301 atatttggga acactattta tatttccaag atgagcgtat tcttacggaa cattttgaaa
    18361 tgataaaaga agcatttctt ttctttgaag attatttatt tgaggtggat ggctacttga
    18421 tgacaggtcc aagtgtctca ccggaaaata aatatcgctt aaaaaatggt attgaaggaa
    18481 atgcttgtct atcatctaca attgataatc aaattctaag atatttttgt gattcatgca
    18541 ttggcattgc aaaacaatta ggagacaatt cggattttat tagtcgtgtg aaggagttaa
    18601 aaaagaaact acctaaaaca aaaataggta gtaatgggca aatccaagaa tggttagaag
    18661 attatgaaga agtagagcct gggcatagac acatttcacc tctatttggg ctttatcctt
    18721 ataatgagat tgatattcat aaaactccgg aattagcaga agcagctaaa atcactatca
    18781 ataggagatt atcaaacgct aactttttat cttcacagga gagggagcaa gcgattaata
    18841 attggttagt aagtggtttg catgctagta cacaaacagg ttggagtgct gcatggctga
    18901 ttcatttttt tgcgagacta tatcaaggtg aacctgctta taaccagatt aatggtttgt
    18961 taaataatgc gactcttggc aatttatttc ttgaccatcc accatttcaa attgatggta
    19021 atttaggttt ggtgagtgga atttgtgaat tattagtaca gagccatcat aattggttat
    19081 cactaattcc agctttacct tctgcttggt cagaaggaga agtgaaaggt ttcagagtaa
    19141 gaggaggata taaggtatcg tttgcttgga aaaatgggga tataacattc ctaaaattgg
    19201 aaggaggaaa caaagatcaa aaagtaagag taagaatata tggcaaaaat actgatgtac
    19261 aaaatattga attggtattt aattcagaaa aaattattga gttaaatttt taggtataag
    19321 tcatgaataa agaaaaaata aaaagaaaat taatcacaat actgtttgta tgtattggga
    19381 tgttatgttt tggattgtta gcaggagtta aggctgataa tcgtgttcaa atgagaacga
    19441 cgattaataa tgaatcgcca ttgttgcttt ctccgttgta tggcaatgat aatggtaacg
    19501 gattatggtg ggggaacaca ttgaagggag catgggaagc tattcctgaa gatgtaaaac
    19561 catatgcagc gattgaactt catcctgcaa aagtctgtaa accaacaagt tgtattccac
    19621 gagatacgaa agaattgaga gaatggtatg tcaagatgtt ggaggaagct caaagtctaa
    19681 acattccagt tttcttggtt attatgtcgg ctggagagcg taatacagtt cctccagagt
    19741 ggttagatga acaattccaa aagtatagtg tgttaaaagg tgttttaaat attgagaatt
    19801 attggattta caataaccag ttagctccgc atagtgctaa atatttggaa gtttgtgcca
    19861 aatatggagc gcattttatc tggcatgatc atgaaaaatg gttctgggaa actattatga
    19921 atgatccgac attctttgaa gcgagtcaaa aatatcataa aaatttggtg ttggcaacta
    19981 aaaatacgcc aataagagat gatgcgggta cagattctat cgttagtgga ttttggttga
    20041 gtggcttatg tgataactgg ggctcatcaa cagatacatg gaaatggtgg gaaaaacatt
    20101 atacaaacac atttgaaact ggaagagcta gggatatgag atcctatgca tcggaaccag
    20161 aatcaatgat tgctatggaa atgatgaatg tatatactgg gggaggcaca gtttataatt
    20221 ttgaatgtgc cgcgtataca tttatgacaa atgatgtacc aactccagca tttactaaag
    20281 gtattattcc tttctttaga catgctatac aaaatccagc tccaagtaag gaagaagttg
    20341 taaatagaac aaaagctgta ttttggaatg gagaaggtag gattagttca ttaaacggat
    20401 tttatcaagg actttattcg aatgatgaaa caatgccttt atataataat gggagatatc
    20461 atattcttcc tgtaatacat gagaaaattg ataaggaaaa gatttcatct atattcccta
    20521 atgcaaaaat tttgactaaa aatagtgagg aattgtctag taaagtcaac tatttaaact
    20581 cgctttatcc aaaactttat gaaggagatg ggtatgctca gcgtgtaggt aattcctggt
    20641 atatttataa tagtaatgct aatatcaata aaaatcagca agtaatgttg cctatgtata
    20701 ctaataatac aaagtcgtta tcgttagatt tgacgccaca tacttacgct gttgttaaag
    20761 aaaatccaaa taatttacat
//
LOCUS       DAVAZV010000041        20624 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVAZV010000041 DAVAZV010000000
VERSION     DAVAZV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.041"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..299)
                     /locus_tag="VQT46_001439"
     CDS             complement(<1..299)
                     /locus_tag="VQT46_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2371454.1"
                     /translation="MMYLDGGGVGCNWWNKRDNIAAAAVSGGMSVYQTYAIKKLIANR
                     GMMSRVVRSAITRYIGGVSMATITNALNIAATVAEVFSLGGAIAYGLDIVDGKFDG"
     gene            complement(279..347)
                     /locus_tag="VQT46_001440"
                     /pseudo
     CDS             complement(279..347)
                     /locus_tag="VQT46_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
     gene            complement(762..974)
                     /locus_tag="VQT46_001441"
     CDS             complement(762..974)
                     /locus_tag="VQT46_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371455.1"
                     /translation="MMVVLISVIVAFLYHKITEYVNNRKIDIVIFLSLLISHFIWNYY
                     FLPIEILIAISGANLLLSFLKKLQIK"
     gene            complement(993..1352)
                     /locus_tag="VQT46_001442"
     CDS             complement(993..1352)
                     /locus_tag="VQT46_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371456.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WILPILLMAGMGDVIIN"
     gene            complement(1330..1668)
                     /locus_tag="VQT46_001443"
     CDS             complement(1330..1668)
                     /locus_tag="VQT46_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HET2371457.1"
                     /translation="MLKKYPCTMQHDQSDCAAAVVSTVLLSYKKELSIMKIREIIGTD
                     MYGTTVSGIVSGLNKLNFTVKAVRVALEDLTPKLTFPAILQVKNDLGQNHFVVLHSIK
                     EKINGTRITK"
     gene            2134..2997
                     /locus_tag="VQT46_001444"
     CDS             2134..2997
                     /locus_tag="VQT46_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371458.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKTHHDLPIEEIRDMLEVVIYLRQHGAGELSKHAEQVVKKLWKKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRMTILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(3049..3621)
                     /locus_tag="VQT46_001445"
     CDS             complement(3049..3621)
                     /locus_tag="VQT46_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET2371459.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQT46_001446"
     CDS             3863..4534
                     /gene="sdaAB"
                     /locus_tag="VQT46_001446"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET2371460.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQT46_001447"
     CDS             4543..5415
                     /gene="sdaAA"
                     /locus_tag="VQT46_001447"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET2371461.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            5437..6069
                     /locus_tag="VQT46_001448"
     CDS             5437..6069
                     /locus_tag="VQT46_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET2371462.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            6095..6193
                     /locus_tag="VQT46_001449"
                     /pseudo
     CDS             6095..6193
                     /locus_tag="VQT46_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(6417..8267)
                     /locus_tag="VQT46_001450"
     CDS             complement(6417..8267)
                     /locus_tag="VQT46_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET2371463.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(8335..9474)
                     /locus_tag="VQT46_001451"
     CDS             complement(8335..9474)
                     /locus_tag="VQT46_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET2371464.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            9532..10698
                     /locus_tag="VQT46_001452"
     CDS             9532..10698
                     /locus_tag="VQT46_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET2371465.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            10837..11163
                     /locus_tag="VQT46_001453"
     CDS             10837..11163
                     /locus_tag="VQT46_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET2371466.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGS
                     IRHDKN"
     gene            11150..11743
                     /locus_tag="VQT46_001454"
     CDS             11150..11743
                     /locus_tag="VQT46_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET2371467.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            11736..12647
                     /locus_tag="VQT46_001455"
     CDS             11736..12647
                     /locus_tag="VQT46_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET2371468.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            12710..13774
                     /locus_tag="VQT46_001456"
     CDS             12710..13774
                     /locus_tag="VQT46_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371469.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(13846..14706)
                     /locus_tag="VQT46_001457"
     CDS             complement(13846..14706)
                     /locus_tag="VQT46_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET2371470.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHIYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTETDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPPSFYHQLDANQIEVQPILD
                     KDFKTLAQEK"
     gene            complement(14828..15814)
                     /locus_tag="VQT46_001458"
     CDS             complement(14828..15814)
                     /locus_tag="VQT46_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET2371471.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEENEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(16086..17561)
                     /locus_tag="VQT46_001459"
     CDS             complement(16086..17561)
                     /locus_tag="VQT46_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET2371472.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(17665..18588)
                     /locus_tag="VQT46_001460"
     CDS             complement(17665..18588)
                     /locus_tag="VQT46_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2371473.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(18602..19531)
                     /locus_tag="VQT46_001461"
     CDS             complement(18602..19531)
                     /locus_tag="VQT46_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2371474.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(19850..20200)
                     /locus_tag="VQT46_001462"
     CDS             complement(19850..20200)
                     /locus_tag="VQT46_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371475.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETADKDVLENSQEELQKAVLFLADEKGSEHTEAELI
                     DNLKEVIAKLKANA"
BASE COUNT         6271 a         4401 c         3710 g         6242 t
ORIGIN      
        1 ccatcaaatt taccgtctac gatatctaaa ccatatgcaa tggctcctcc taatgagaaa
       61 acttcagcaa cagtagccgc aatattaaga gcattagtaa tagttgccat actaactcca
      121 ccaatatatc ttgttatagc acttctaacg actcggctca tcataccacg attagcaatt
      181 aactttttaa tggcatatgt ctggtatact gacatccctc cagaaactgc agctgcagca
      241 atattatcac gtttgttcca ccagttacaa ccaacaccac ccccatcaag atacatcatc
      301 tcttcttgct caagaacaac ataattattt ggtaatacga gttccattta ttttctcctt
      361 ttttattaag catagttagg atcgtttcct aacaagtgat cgttgacttt gtttatagca
      421 cttagttacc tagataagat atcctttagc ttgcttccaa aatttaagtc tgcacctata
      481 atatgagttc atattagtac tgctaaatcc tatctatagt aatgtcaaac acctaaataa
      541 agtcatctct ccaattcatt caagaaatga agaaaggcaa aaaatcttta aaataagaaa
      601 agtgcatatt atcaggtgtt caaaaatctt gataatatgc gttatataat agaaaaattt
      661 actcaatttc actttcaaat tgagtttttt cccaacctcg tttttaattt atatcttcaa
      721 taaaatctaa tgacctagtt gatatgtcat atggaataat attatttaat ctgtaatttt
      781 tttaaaaaac ttaataataa atttgctcca ctgattgcta tcaatatttc aattggtaaa
      841 aaatagtaat tccaaataaa atgagaaatc agcaatgata gaaaaataac aatatcaatt
      901 ttcctgttgt tgacatactc tgtaatttta tggtacagga atgcaacaat aactgaaatt
      961 aaaacaacca tcataatact attatcctat tctcaattga ttatcacgtc gcccatccca
     1021 gccatcaata atattggtaa aatccaatca gctccagcac caattccagc agatgcaata
     1081 cttctaataa cagtatttgc aaaagcattt ccaatatgaa ttcctaatac tcctaaacct
     1141 ttaacaatcc cagctaccag tgcggagcgt aatccataag atgcaagaac tagttgaagg
     1201 cctccacctc ctgctgctgc taatgctgca tatgctgcac cagtaatggc tcctgtaatt
     1261 gcccacctgg gtatatatat agccccccca tcaaggtaca tcatctcttc ttcatcaatc
     1321 acaacataat tatttggtaa tacgagttcc atttattttc tcctttatac tatgtaatac
     1381 cacaaaatga ttttgaccta aatcattctt aacttgaaga atcgcaggaa atgttaattt
     1441 tggagtcaaa tcttccagtg ctactcgaac agcttttact gtaaaattca acttattcag
     1501 acctgaaaca ataccactga cagtcgttcc atacatgtct gtaccaataa tttcccgaat
     1561 cttcatgatt gatagttcct ttttgtaaga taaaagaact gttgaaacaa ctgccgcagc
     1621 acaatctgac tgatcatgtt gcatcgtaca aggatatttt tttaacatag aaatactcaa
     1681 ttctttagaa ttaatctaac ttttctttga tgtcacccaa acctcaatca ctgcccagta
     1741 gttcttgaat cagtttattt tcaatcgtat cattctttgt tcttgatatc tttccaagca
     1801 ttgtagtaca gcagattttt gtccaaggac taagcctcct ttaacaactc aagctccctt
     1861 acattatatc gaccagcccc atggaaagat tatggccaga ctaatcaatg atataataca
     1921 tactagaata caaaatattt ttttattcat actttttctc ctatctttat tttctaccta
     1981 catcatacct cttattaagc tcattttaaa attacgttaa cttttttcac aaatttattt
     2041 cgactttctt ttttactttt tacattgcta tgatacaata tttttaacaa aattttattg
     2101 tttgttaact tttttcacag aaaggagaaa atcatgcgtt atgatttcgg aaaggtctat
     2161 aaagaaatac gtgagtcaaa ggggctgacc caagaagagg tctgtggggg tgttctctca
     2221 agaaccagct tatcaaaaat cgaaagtggc aagacaaccc caaaatatga aaatatggaa
     2281 tttcttctcc gtcaaatcaa tatgagtttt gaagagtttg aatatatctg tcaactttat
     2341 caaccaagtc aacgcacaga gattatgcaa acctatctca atatgcgttc cattatcggg
     2401 accagcgatc ttgtcaattt atttcaaaaa tgccaagact acctcaagac ccaccacgat
     2461 ctccctatag aagaaatcag agatatgctt gaagttgtta tttatctccg tcaacacggg
     2521 gcaggggaac tatcaaaaca cgcagaacag gttgtcaaaa aactttggaa aaaaattgaa
     2581 aaacaagata catggtatga gagtgatcta aaaatcctca ataccattct tttcagtttt
     2641 cccattgaat acctccatct catcactgga aaaatattgc aacgcctaga agtctataaa
     2701 aactatcaac atttatatga cttgcgaatg acaattctat taaacctttc cacactctat
     2761 ctatacaatc aagataaaaa catgtgtaag caaatctgct acactttact ggaggacgcc
     2821 aagaataaga aaagctacga taggctggct atctgctatg tccgtattgg gatttgtaca
     2881 gacgattcta aacttatcca aaaagggttc tcccttctgg agctaaccga ggaaacttct
     2941 atgctgtctc atctcaaaaa agaagtagag atctattacc aagcgaagga aagataaaaa
     3001 agccgaggga tttcctcgac tctttacata ttatttgttc gttagttctt aataccagcc
     3061 attgttaagc cagaagtttt tagcagcagt ccatgaaccg taacgtcctg caacgtaggc
     3121 atctgctaca cgttcttggt tttcagctga gtagtcaccg ttcaggtatg aatctgttaa
     3181 ttggtaacgt ccgatataac gtccatttgt agctgtatag ctaccacctg attctttttg
     3241 agcgatccat tctttggctt ctgcttcaga tccgcttaca gttgaaacaa ctgtttcact
     3301 tactactgga gctgaaacag tttcatcttg agcggctggt gccgcataag tagctggcgc
     3361 tggtgttgca acaggcgcta cagggccatc gataaccaac tcttgatcaa cataaatcaa
     3421 atgaatgtta tcaatgtggt tgttttctgc caatttttca actgttgtgt tgtgagtttc
     3481 agcgatttct gaaagtgtat caccttcttt aacagtgtaa gttgatgatt cttgagcaga
     3541 tacaaatgat ggagaaaata ctgcaaacaa ggcagctact cctgcaagag ttgctttaat
     3601 ctttttagtt attgatttca tattcgaaaa ttctccttct ttctatagtt ctatcatacc
     3661 ctttaaatat tactgtttct tgacactttt atgtagaaat attacaaaat tattttttat
     3721 ttccctaaat aaggtgtttt ttgtcataaa agatactatt tttatgctat ttgaggtatt
     3781 agaaaggttt tcatccacaa ttaaagccaa gcccctcatt ctttgatata atagagataa
     3841 gaatttttat aaggggaaac tgatgaaatc acttcgtttt caatctgtct ttgatatcat
     3901 cggaccagtt atgattggcc catctagtag ccataccgct ggtgctgttc gtattgggaa
     3961 gattgtctct tccatttttg atgatactcc gacagaagtt gaattccaac tttttaactc
     4021 atttgccaag acctatcgtg gtcacggaac agacctagcc cttgttgcag gtattttagg
     4081 aatggataca gatgatcctg aaattccaaa tagtctggaa attgcccaca agcgtggtat
     4141 caagattgtc tggaccattc agaaagacag caatgcccct caccctaaca ccactaaaat
     4201 tactgttaaa aatgcccaca agaccatcag cgtgactggt atttctatcg gtggaggaaa
     4261 tattcaggta accgaactca atggttttgc cgtctctctc aatatgaata caccgactat
     4321 catcatcgtt catcaagata ttccaggtat gattgccctt gttacagagg cgctttcccg
     4381 ctatggtatc aatatcgccc agatgaatgt cactcgtgaa aaagctggtg aaaaagccat
     4441 tatgattatc gaagttgaca gtcgcaactg tgatgaggct atcgaagaaa ttcgaaaaat
     4501 ccctcatctc cacaatgtca atttctttaa ataggaggaa gcatgtttta ttctatcaaa
     4561 gaattggtcg agcaagcaga tctggacttt caaggaaatg tcgcagaact catgattaca
     4621 acagagtttg aattgaccgg tcgcgaacgt gaagaagtct tccttctcat ggaacgcaat
     4681 ctggaagtta tgaaagcctc tgtccaactt ggcctcaatg aaaataaatc tcgtagtggc
     4741 ctgacaggtg gagatgctgc caaattggat cactacatca aaaacgaaaa aactttatca
     4801 gattacacga ttctctctgc tgcccgaaat gctatcgcag tcaatgaaca caatgctaaa
     4861 atgggcttgg tctgcgctac tcctaccgca ggaagtgccg gttgtctccc ttccgttctc
     4921 actgctgcta ttgaaaaatt agacctcagc cacgagcaac aattggattt cctctttgct
     4981 gctggtgcct ttggactagt catcgcaaac aatgcctcca tctcaggtgc tgagggtggg
     5041 tgtcaagctg aagttggttc agcctctgct atgagtgctg ccgccttgac tctggctgca
     5101 ggtggaacac cttatcaggc cagtcaagct attgcctttg tcattaaaaa tatgctaggc
     5161 ctcatctgtg accctgttgc aggtttggtc gaagttccct gtgtcaaacg taatgccatg
     5221 ggagctagct ttgctttcat cgcagcagac atggccttgg caggtatcga atctaaaatc
     5281 cctgtggatg aagtgatcga tgccatgtac caagtaggag caagcatgcc aactgccttt
     5341 cgtgaaacag ctgaaggtgg actcgctacc acccctactg gtcgtcgcct ccaaaaagag
     5401 attttcggag aataagctta tcaaatagga gaaaccatga cctctatcac agcgattttt
     5461 ttcgatttgg atggaaccct cgttgatagt tctatcggga ttcacaatgc ctttacctat
     5521 acctttaaag agctgggggt gcctagccct gatgccaaaa ctattcgtgg ttttatggga
     5581 ccacctctcg aaagtagttt tgcgacctgc ctgtccaaag accaaatttc tgaagccatg
     5641 cagatatatc gttcttacta taaggcaaaa ggcatctatg aagctcaact ctttcctcag
     5701 attatagact tgcttgagga gttatcgagc agttatccac tctacatcac cacgacaaag
     5761 aatacatcta ctgctcaaga catggccaaa aacttggaaa tccatcattt ctttgatggt
     5821 atttatggtt ctagccctga agcaccccat aaggcagatg tcattcacca agccttacag
     5881 acacatcaac tagcaccaga acaagccatc atcatcggag ataccaagtt tgatatgctg
     5941 ggagctcgag aaacaggtat tcagaaattg gccgtcactt ggggatttgg agagcaagca
     6001 gatctactaa actatcaacc tgattatatc gctcacaaac ccttagaagt tttggcgtat
     6061 tttcaatagc atagactggg cgacaactct atttcagaag aaaatgaagt aatactcaat
     6121 gaaaatcaaa gagcaaacta ggaaactagc tgcgggctgc tcaaaacact gttttaaggt
     6181 tgtagatgga actgacgaag tcagctcaaa acactgtttt gaggttgtgg atagaactga
     6241 cgaagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag tcagtaacca
     6301 tatacggcaa ggcgacgttg acgtgatttg aagagatttt cgaagagtat aagtctctac
     6361 ataataaaac gcatattacc aaggttattt aacttgataa tatgcgtttt tcttttttat
     6421 tcaatgtggg ttgtttgatt agcaaaggcg ataatagctt gcttcaactc atctccactg
     6481 agagtgcgga actctccaat cttttgattg atggattcta aaggcatgac attaacctta
     6541 ccaacgaaaa tcttatccat aacttgatta tcaacgagtt cggttgatac caagagttct
     6601 tcgtagagtt tttcacctgg gcggattcca acttcaacga ttggaatttc actttcagtg
     6661 tggccactta gaagcaccat cttcttggcc aagtcataaa tcttgactgg tttgcccata
     6721 tcaaggataa agacttcccc atctttggca taagcaccag catggataac cagacggcta
     6781 gcttctggaa tggtcataaa gtaacgggtc atgcggaagt ctgtcaccgt tacaggccca
     6841 ccttcagcaa tctgacgttc aaagactgga atgacactac cacggctacc aagaacattc
     6901 ccaaaacgaa ctgcacagta ggttgattgg ctacgttggt taaagccagt gacaatcaac
     6961 tccgccacgc gcttggttgc tcccataaca tttggtggat tgactgcctt atctgtcgaa
     7021 atcataacca tcttaggcac cttggcttca tcaacggctc tagcaacatt gtaagttcca
     7081 cggatattgt ttttgaaggc ttcttttgga ttgcgctcca tcataggaac atgcttgtgg
     7141 gctgccgcat gataaacaat agcaggtttg tactgctcaa agacttgcaa caaacgatca
     7201 tagtcttgaa tgtccgcaat cacaggtaca taatcaatcc cttggaactt acgaatcaat
     7261 tcatgataaa caaggtagat tgagttttcc ccatgaccga gcaagacaat gcgttcagga
     7321 ttgaagcgac taacttgacg acagatttca gaaccgattg aacctccagc tcctgtgact
     7381 aagatggtct tacctgtcag ttctgcaccc agacgcgatt cgtcaagacg gatttcctga
     7441 cgacccaaaa ggtccgtaat atcaattttt tggaagccag tacctgcttg gtgaaggccc
     7501 tgaacaacag tttcaacctt aggcatcttg taacatttga cacccagctt attacacatc
     7561 tgcaagatac gctcatattc tgacggatcc agcgacggaa tcgcaacgat gacacgctcg
     7621 atttgatggc gtttggctaa ttcaggcaga ttgtcataag agcccaaaac aggaatacca
     7681 ccaagttttt gacccttttt cttagaatcc ttatccaaaa taccgaccag ttctaattca
     7741 ctggttggat gttggtaact atccataaag agagccccac catcaccggc accaatcaag
     7801 aaggtccgac ggtgttctcc atcaccacta ccttttttgc gtctggagta gattaactgc
     7861 caagtaatcc gtggcaataa aatcaagaag gtactcaaca agataaagag aatgataaaa
     7921 cggatggaga agagtggcaa gaaggcataa cagatactat atgacaagac actgctagca
     7981 gtcacaccaa aaaagatttt catgaaatcc gtaatcttgc tgtaacgact aatactcgcg
     8041 ctcaagcccc aaaaatcaac catcaattga tagaacagga aggccaaact cgtatagata
     8101 atgtagtcaa caggtgctgg attaatcagc ccataaaata aaatataaga tacaatgatg
     8161 gaaaccacca tactgaaaat atcaaatatt ccccagaaaa cctgcttttg ttgtttattt
     8221 aaaatttcca ccagatcaat cacataatct gtgagttttt tattcataga aatttactcc
     8281 tccttaaaat agttctacta tattgttatt atagcacatt ttaatttatt tggcttattt
     8341 ttccaaataa attactgttc ccttgtactc cttcttccat ttaaatcctc taattaaacc
     8401 tacaatcgtc ccaaggccat aagcaaagtg aatggaaaat aaaagaaagg gcatcacaat
     8461 tagaaatcca tttttatgtt ttaataaagt cagcaaagtg agtaatgaca gtaatgataa
     8521 aagtagaaaa taggcaccta atagtaaagt tatgaatacg aatgtgatcg gtaacaatgc
     8581 tagactaaac acaagactca aaacaaataa acaaggaaca taatgaaata atgataaaca
     8641 cttaaactga acatgacttg tcaagccaat ccacaaacca tttgaatact tttgatgcag
     8701 cattttcttg aatgttggtc gaatatactg ataagataga atacttgggc tatagcggat
     8761 tttataacca tgttctcgaa ttctataatg aatatcatta tcttcagttc ggccaagttg
     8821 ctcatttact aaaccaacct tctggaaaac ctctcgttta tacatcccat gaaaaataga
     8881 agaaacatat ctatcctcgg aactatttcg ataattggca atgctactgc caaacatatt
     8941 ttcctcaaca agatgcaagg tctctgccca ttttcctttt cctttgacaa tcgtcggtct
     9001 aggccctcca cagacaaatt caccttgttg aataacagcc acattgttca ttacaaaact
     9061 ctcagtaact tttgaatgag catcaatttt taaaataagg ccccctacag aatgcttaac
     9121 tcccaggtta aaaccactag cttgattttt cttaggattg ttatacaatc taattgagtt
     9181 aaactctgca tcttctttta taaattgctg aatgatagct gtggtcccat ctgtggacat
     9241 agcatttata aatagaattt caatattctc tttaggatag gtttgatttt ttaagtcttc
     9301 aattagacca ggcagatatt tttcttcatt gtatgcactg attacaatgg atacgagaag
     9361 actttcaaca ttttgagtca ctactactct cctgaatttt cccttccacc attctatcat
     9421 aattttcaag acttttccat ttttatcttg aaagccagaa accttacttg acattatagt
     9481 gaaaaagcct taaaataagc tgttattaaa atcagctaga agagatatta tatgaaaaag
     9541 caatcactct tttttgttcc aggtattatc ctgattggtg tttccttgcg aactcctttt
     9601 actgttttac ccattatttt gggaaatatt tcgcaaggtc tggaggtaga agttagttcg
     9661 cttggtgtct tgaccagcct gcctctcctt atgtttaccc tcttttcacc attttctacc
     9721 cgactggctc agaaaatcgg cttggagcat ctcttcacct acagcctctt cttcttgacc
     9781 atcggctcac ttattcgact aatcaatctg cccctgctct atctaggaac cttgatggtt
     9841 ggggcaagtg tcgcagtcat caatgtcctg cttcctagtc ttatccaagc caatcaacca
     9901 aagaaaattg gttttctgac caccttatat gtaacgtcta tggggattgc aacggctctg
     9961 gcttcctatc tagctgtgcc cattacacaa gccagttctt ggaaaggact tatcctcctc
    10021 ctcacgttac tctgtctagc aacttttttg gtctggctcc caaatcaccg ctataatcat
    10081 agactagctc cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa taaacaggtt
    10141 tgggcaatta ttatcttttc aggttttcaa tccttgatct tttacaccgc catgacctgg
    10201 ttacctacca tgtctatcca tgcaggtcta tccagtcacg aagctggctt gctgacttct
    10261 atcttatctc tgattagcat tcctttttca atgaccatcc caagcctgac aaccagttta
    10321 tctactcgca accgtcagct catgctcact ctggtttcac tagctggtgt ggtcggcatt
    10381 tccatgctct ttttcccaat caataatttc atttactggc ttgccatcca tctcctcatc
    10441 ggaaccgcaa ccagcgccct cttcccttat ctcatggtca acttttcact caagaccagc
    10501 gcccctgaaa agacagccca attgtccggc ctatctcaaa caggaggcta tatcctagca
    10561 gcctttgggc caaccctctt tggttacagt tttgacctat tccactcttg ggtaccagct
    10621 gtagctgccc tcttgctcat cgatatcctg atgactgtgg ccctctttac agtggacaga
    10681 gcggataaga tcctttaaac ttctagtttt agctagaagt tttttatata taaaaatttt
    10741 acacatttct cttgacaggg ctttctttta gatgtacaat gtatgtgtag aaaaattata
    10801 tataaaaatc ttacacatta gaaaaggagg tttcccatgt actttccaac atcctctgcc
    10861 ttgattgaat ttctcatctt ggctgtactg gagcagggtg attcttatgg ttatgagatt
    10921 agccaaacca ttaagctgat cgctaatatc aaagaatcca cactctatcc cattctcaaa
    10981 aaattggaag gcaatagctt tctgacaacc tattctagag agttccaagg tcgcatgcgc
    11041 aaatactact ccttgacaaa cggtggtata gagcagctct tgaccctaaa agatgaatgg
    11101 acactctata cagacaccat caatggcatc atagaaggga gtatccgcca tgacaagaac
    11161 tgaatacctg actcagctag aactctatct caagaaacta cctgaagctg accgtatcga
    11221 agccatggac tatttcagag agctctttga cgatgctgga gtcgaaggag aagaagaact
    11281 catcgctagt ttgggaactc ccaaagaagt ggcccacgaa gttctatcca atcttctcga
    11341 taaaaaaatc aatgaagcac ccgctcaaaa aaataaccga caaattttac atatcgcctt
    11401 gttagccctc cttgcagcac ctatcggcat tcctctggga atcgccatcc tcgtgaccct
    11461 gttcgcaatc cttgtagccg ctttgactgt cattctggct ttctttgcag tttccatact
    11521 gggtatcatc ggcggattcc tatttttagt tgaaagtttc actgtcctcg cccaagccaa
    11581 atcagccttt atcttgattt ttggttctgg tttactggct atcggtgctt cttcgctagt
    11641 tttacttggc atttcctatg tagctcgctt cttcggtcta ctcattgttc gtctggtaca
    11701 atttgttctt aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca aaaggatttc
    11761 tcatctttgg tgtggtgact accgttatcg gctttatcct gctttttgta ggtatccaat
    11821 ctgacgggat taagagccta ctttccatgt ccaaagaacc tgtctatgat agccgtacgg
    11881 aaaagctaac ctttggcaag gaagtcgaaa acctagaaat tactctccac caacacacgc
    11941 tcaccatcac agactctttc gatgatcaaa tccacatttc ttaccatcca tctctttctg
    12001 ctcaccatga tcttatcacc aatcagaacg atagaactct gagtctcact gataagaaac
    12061 tgtctgaaac tccgtttctc tcttctggaa ttggtgggat tcttcatatc gcaagtagct
    12121 actctagtcg ttttgaagaa gttattctcc gactaccaaa agggagaact ctaaaaggga
    12181 tcaacatctc agccaatcgc ggacaaacca ccatcataaa tgctagcctt gaaaatgcga
    12241 ccctcaatac aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa aacagtaaac
    12301 tcacaacgcc caatatcgtt aatatctttg atacagttct tacagatagt cagctagagt
    12361 caacagagaa tcacttccac gctgaaaata tccaagtcca tggtaaggtt gaactgactg
    12421 ccaaagatta tctcagaatc atcctagacc agaaagaaag ccaacgaatt aactgggaca
    12481 tctcaagcaa ctatggttct atcttccaat tcacaagaga aaagcctgaa tcaagaggta
    12541 cggaattaag caacccttac aaaactgaaa aaaccgatgt caaggatcaa ctcattgcga
    12601 gatctgatga taatattgat ctaatatcca caccaagcag acgttgacaa aaacgcttac
    12661 atctgctact atggaagcat atttatctaa ctaaaaagga ggttctacca tgaaacaaga
    12721 atggtttgaa agtaatgatt ttgtaaaaac aacaagcaag aacaagcctg aagagcaagc
    12781 tcaagaggtt gcagacaagg ctgaagaaac gatagccgat ctcgatacac caattggaaa
    12841 aaatactcaa gtagaggagg aagtctctca agctgaagtc gaactggaaa gccagcaaga
    12901 agagaaaatt gaaactcctg aaggcggtga agcgagaaca gaaatagaag aaaagaaggc
    12961 atctaattct actgaagaag agccagacct ttctaaagaa acagaaaaag tcactatagc
    13021 tgaagagagc caagaagctc ttcctcagca aaaagcaacc acgaaagagc cacttcttat
    13081 cagtaaatct ttagaaagtc cttatatccc cgaccaagct ccaaaatcta gggataaatg
    13141 gaaagagcaa gtgcttgatt tttggtcttg gctagtggaa gcgatcaaat ctcctacaag
    13201 taagttggaa acaagtatca cacacagtta cacagccttt ctcttgctca ttctgttttc
    13261 tgcatcttcc tttttcttta gtatctatca catcaaacat gcttactatg gacatatagc
    13321 aagcattaac agtcgcttcc ctgagcagct agctccttta actctttttt ctatcatctc
    13381 tatcctagta gcgacaacac tcttcttctt ttcattcctc ttgggtagtt tcgttgtgag
    13441 acgatttatc caccaggaaa aggactggac gctagacaag gttctccaac aatatagtca
    13501 actcttggca attccaatct tcctcactgc tattgctagt ttctttgctt tctttgatag
    13561 cctacgattt acggccctct tgtgtgtgat tagcattgga atcattctgc ttgccagtct
    13621 ccatatcatt acaagaccaa gtcaagcaag tgaaaccgac tccttctatc aattattctt
    13681 gtctgtcctt gtgaacggag ttattatcct cctcttcttt gtagctgaag tggcactgat
    13741 tggagattat cttcgtatct tggcctttct ttaaaattca atcctgtcat ccttggcagg
    13801 attttttcta tgtcaaaaaa gcaagtcgat tgacctgctt ctgctttact tttcttgtgc
    13861 taatgtttta aaatctttgt ctaatatggg ttgcacttct atttgattgg cgtctagttg
    13921 gtggtaaaaa gatgggggta atacctctaa gaattttgca tagtccaagc gagcaatggc
    13981 ttcatagtct tctggtttag agccatctcc tgtgatttga accaagtcaa tctcccactg
    14041 cacttcctta tccaccaatt gctcaatata ggctgcagga acaaacggtt ctctcggtaa
    14101 aactgtcttg actccttgag ctagatggta aacgccatgc acttttcctt ctccatcctg
    14161 atagaaggaa actctcgcaa agtaggcatc tgtctcttga accgcacgca cacgcgcttc
    14221 aaactgagcc aaaccatctg cctctaaaaa gcttttcaag ttctcacgac taaagaaaat
    14281 aggattaaaa attccttggc aaatcgtaaa acgagctaca gggtctgcta gataggcttg
    14341 aatacttgct tggaaataag cttcaaaatc aaaaccatct agcccttcaa tatcagtccc
    14401 tgtataagca agcaaagcat ctaaaaatga cttgataatc tgccagtctg tctctgttag
    14461 taggtcagga agatcgacac ggtaagcctt ttgaccatca gcataactga ccttaaaaag
    14521 aaattgtgat tgccccacta tcgcacactc aatatactcg agacgattaa gaggctgacg
    14581 gagatagact acatcataga tatgtgactc caaaccgtct agcaatgcca agatcgactt
    14641 ggcattcaaa atctcttgtt ctcctaaaat gctctgttta tttggaataa aaaatgtttt
    14701 cgccataact ggactccttt gaaatcgctt acatacagta taccttattt ttctgaaaga
    14761 tacagaaaca aactttagat ttttgagtac aaagcataga aaaacagccc ctgaggactg
    14821 tttgatctta tacagtagct gcttgatcca agctttcacc gatagcggct aggcgctcga
    14881 tcacttcagc ttgtgtcaat tcattttttg aaacatagcg gttacgtggg tgaacacggc
    14941 actcgtgtga gcatccacga aggtacttgt cttcattttc ttctgatgtc aagatacgac
    15001 ggttacagaa gggatttcca cagttgacat aacgttcaca tggtgttcca tcaaaccagt
    15061 ctttccctac gatggttggg ttgacatggt tgacatcaac ggcgatacgc tcgtcaaata
    15121 cgtacatttt tccatcccaa agctcacctt gaacttctgg gtctttaccg taagttgcga
    15181 ttcctccgtg caattggccg acatctttgt agccttcacg gaccatccag cctgagaatt
    15241 tctcacagcg aacgccacct gtacagtaaa ccacgacacg cttgtccatg aatttttcct
    15301 tgttatcacg gacccattgt ggtaactcac ggaagttgcg aatatctggg cgaatagctc
    15361 cacggaaatg tcctaggtcg tactcataat cgttacgtgt gtcaaggaca acggtatctt
    15421 tatcaagaag cgcttctttg aactcttttg gagacaagta agcacctgtt gtttcaagtg
    15481 ggttgatgtc attgtcaaag tcgttgtctt ccaaaccaag gtggacaatt tctttcttgt
    15541 agcgaacaaa catcttcttg aaggcttgtt cattttcttc gtcaatcttg aaccagagtt
    15601 cttccattcc tggaaggctg tgaacgtagt ccatgtattt ttgagttgtt tcatagtcac
    15661 ctgaaactgt tccgttaatt ccctcgtcag cgactaggat acggccttta agaccgattg
    15721 atttacagaa agccaagtgg tctgcagcaa attgctctgc attttcaatt ggagtataaa
    15781 ggtagtaaag taagacacga atatcttttg ccataagatt tgttctcttt tctattctta
    15841 aattttctaa attttttatt tatccatact agtatacctg cttgagaaaa cgaatgcaat
    15901 ttatttgact ggaaattgta gaggattctc gaaatttcct gaatggttaa aataaggaca
    15961 agagaaaaca tggatatcta tatccttgtg ccaaaaaaac cactgccctc cccagaccaa
    16021 cctgaggaaa gcagtgattc ttattttagg agttaggaat gaatacacga aatcaattta
    16081 gctgattatt ttttgttttt caagaattca tcgtattgtt tttgcatttc gttcaatact
    16141 ttttcgtagg caccttcaga tttcaatttt tccatcaatt ctggaatcgc tttatctggg
    16201 tctacagtac cagtgttgat agctgtatca aattgttgca ttgtgttagc aatagctgag
    16261 atttcagatt tcacattgtc agtattgaag ataaatccaa gcgctggaga ttctttagct
    16321 tctgccaatt ctttcttaga attttcgatt tgttggtctg taacgttttc gttgatgtaa
    16381 aggatccagt tgttaccagt gttccatcca cccatgtgag tgtttccttt gtagccatca
    16441 agaacgcgaa cacggttttc tttaccttca attttttccc agttcttgcc ttctggaccg
    16501 taaacaagac cgttcaaaag ttctgggttc gtattcaaga ggttcaagat ttccattgat
    16561 ttttctttgt tcttagagtt gtttgagatg acaaagttag caacttgtgt tgtttggttt
    16621 ttcttgatga agttagtgat tggtttgatt tggatatctt tgttggcaac acgtgaaagc
    16681 aagctgttac cgtagtcagc tggtcctact gtttcttcac gaacgaacca agtatcttgt
    16741 tgaaggtcaa atgaagtatc gcttgttgcg acgtcttttg gaatgtagcc agcttcatag
    16801 aatttgtgaa gagtcttcaa gtgttctttg aaacgaggca cttcgtaacg gtttacaact
    16861 ttagtagtat cgccttcaag gtcaataacg aatggaagcc cgtttgctac tgggtagtca
    16921 aaattatcag atgggatgaa aactttacca atagcaaatg gtactacgtc tggagctttt
    16981 tctttgattt gtttcaagac tggctcaaga gtttcgtaag aagtaacacc tgaaatatcg
    17041 ataccatatt tggcaaggag agttccgttg aaggcaaagt tttgagatga tgctacgttg
    17101 gctgcaactg gtacagcata aatcttacca tttacagtat tacccttgat ataagctgga
    17161 tcaagtgcct tgtaaaggtc tttaccttct tttttgtaca attctgtcaa gtcagcataa
    17221 gcaccttttt gagcatttac aatatagtta tctgcaaagg cgatatcata gttttcacca
    17281 gatgatgtga taactgacat tttcttacca tagtcacccc agccaaggta ttggatatcc
    17341 aatttggcac caactttttc ttcgatgatt ttgttggcat ttgctaacaa ttcatccaag
    17401 ttatctggtt tgtcaccgat ttggtacatt ttgataacag gtttgtcacc tgaatcagca
    17461 gcttttttgc tgttacctgt caaatttcca caagcagcaa gacctgcagc cagagcgact
    17521 acactagcag atgcaaaagc atattttttc cagtttttca tgataaaaac tccttttttt
    17581 atttttaaac ttataaacaa tgtaatgatc ttaacttcac acaagggaag ttgggaactg
    17641 agaaatgttc tttttcaata agcactattc tttcacacca ccgatagtca aaccttttac
    17701 aaagtagcgt tggaagaatg gatacaaaat cgcgattgga agggttgcta ccacaaccat
    17761 ggccatacga cctgtttctt tcggtagagc aactcccagt tgaccagtca agccgaccgc
    17821 tttggcaatg tagtccatat tttgttggat ttgcatgagc aaatattgca atggatacaa
    17881 gttatcactc ttgatgtaaa gaagggcgtt gaaccagtca ttccagaaac caagagctgt
    17941 caaaagcgtg atggttgcga tacctggtag tgacaatggc aaacagattt ggaagaaaat
    18001 ccgagcctca ctggcaccat cgatacgagc cgattcgaga atggcttctg gaatggtctt
    18061 cttgaaaaaa gaacgcatca agatgatatt gaatggtgag agaagcattg gaacaatcaa
    18121 ggcccaaaca gtgtcaccaa gctgaagtac acgggtcacc atgatataac ctggtaccaa
    18181 accagcgttg aacaacatac tgagaaggac gaagatggta aaaaatctgc gatacttaaa
    18241 ggttgtccgt gaaatagcgt aggcataggt tgttgtgata aagacatttg tcaatgtccc
    18301 aactacggtt acaaagacag agatgaagag ggcttgtagg attttatcct taaactgtgc
    18361 caaaaactca aaaccgtcta agccaaattg ggatgggaag aagctatagc cgtattggag
    18421 gaggcttttc tcgtctgtca ctgaaataat gataacgaat acaaaaggta ggatacaaga
    18481 gagggcaatc aaacccgaaa tgatactgaa gaagatatct gctttcttac tgaaggagtg
    18541 aatgccgaca ttatcaattt tttctttttt aattttcttt tttgccatat tctcctcctt
    18601 tctagaacaa agctgagttt ggatcgactc gtcttgcaag caagtttgat aggataacca
    18661 gaatcaaacc aacaacggat tggtaaagac cggctgctgc agccataccg atatctgctg
    18721 tctgagtcaa accattaaag acatatacgt ccaaaacgtt ggttacattg taaagctgac
    18781 cagcattgtg tgggatttga tagaagagac cgaagtctgc gcggaagata tttccgactg
    18841 caaggatggt caatacagtt acaagcggag tcaactgagg aatggttacg ttgcgaatac
    18901 gttgccactt gctagctccg tccactgtcg ctgcttcgta gtaggttgga tcaattccca
    18961 tgatcgtcgc atagtacatg acactgctat atccaaagcc tttccaaata cctaggaaaa
    19021 gtaggagata gggccagatg cccaggtcag cgtagaaatt gacttctttg agaccaagac
    19081 tttccaatag atgattgaac acccctttat caatatttag gaaggcatct gtaaagaaac
    19141 tgatgataac ccaagacaag aagtaaggga acaacataga agtttgaaaa atcttcacca
    19201 ttctcttaga acggagctcg ctgaggataa tggcaatccc tacagataca actaaaccta
    19261 gaaagataaa gccaagattg tagaggacag tatttcgtgt gataataaag gcgtctcttg
    19321 aactaaataa gaatctgaaa ttatcgagtc cgacccattt actatttatg atactatcta
    19381 tgaaaccatt actggtcatg tggtagtctt tgaaggcaac cacgttccca aatactggaa
    19441 tgtaaaagaa tagaatcaac cagagtgccc ctggcaaaac catcaagaga aagatccagt
    19501 tgtctctcaa tgtttttgaa aactttttca taatttcctc cctttttatt ttgatatcca
    19561 tctaaaaatt cttttttaga cttttgataa cgattacatt attagtatac tcctatttgc
    19621 aggttaggtt aaactcctaa ttatagaaaa aactccacaa attatgtagc agatttaaaa
    19681 ctttatcacc actatcaaac aaatgtccta aatcaattgt ttattttatc tctattagcc
    19741 cagtgatggc gtcactctgt tataagcatc caacaacggg gtatactgaa aaatctccag
    19801 actagggaac tcagcgatag ttcctaatct ggagattttt aatatgttat taggcgtttg
    19861 ctttcaactt agcaataacc tctttaagat tatcaatcaa ctctgcttca gtatgctcag
    19921 agcctttttc atctgccaag aacaaaactg ctttttgaag ttcttcttga gagttttcaa
    19981 ggacatcctt atctgctgtt tctttgcccg ctgtttgtcc tccatcctta gttgctgact
    20041 ggctttcctt aatggactct agggaagcaa tggcatcttt gactgtttgc aagatatcac
    20101 gtaaaccttg ctctgtcaaa ctatcatctg caaaagcttt cttagcctct gccaaaacca
    20161 gacgtgctga atctgtggta ggattcgata cacctgtcaa tgatctcaaa agattttcta
    20221 aagtttgagt ctgcttacta atactagact aaaatcaaaa agcattatat aacagtgata
    20281 tgaaatcaac taaagaagaa atccaaacta tcaaaacact tttaaaagac tctcgtacag
    20341 ctaaatatca taaacgcctt caaatcgttc tatagtaaaa tgaaacaaga acaggacaaa
    20401 tcgatcagga cagtcaaatc gatttctaac aatgttttag aagtagaggt gtactattct
    20461 agtttcaatc cattatattt cgtctgatgg gcaaatctta taaagagatt atagaacttt
    20521 tatagtagtt tgaaataaga tgtgaacaac tctatcagga aagtcaaatt aatttataga
    20581 aatattttag cagctaaggt gtactgttat agattcaata cact
//
LOCUS       DAVAZV010000042        20251 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVAZV010000042 DAVAZV010000000
VERSION     DAVAZV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20251
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.042"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            21..866
                     /locus_tag="VQT46_001463"
     CDS             21..866
                     /locus_tag="VQT46_001463"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET2371476.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(1013..2074)
                     /gene="dinB"
                     /locus_tag="VQT46_001464"
     CDS             complement(1013..2074)
                     /gene="dinB"
                     /locus_tag="VQT46_001464"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET2371477.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIRDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKSVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGVSYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILLAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSKKERGVRLLGITMTGF"
     gene            2422..4746
                     /gene="pflB"
                     /locus_tag="VQT46_001465"
     CDS             2422..4746
                     /gene="pflB"
                     /locus_tag="VQT46_001465"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET2371478.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(5113..5331)
                     /locus_tag="VQT46_001466"
     CDS             complement(5113..5331)
                     /locus_tag="VQT46_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371479.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(5427..5665)
                     /locus_tag="VQT46_001467"
                     /pseudo
     CDS             complement(5427..5665)
                     /locus_tag="VQT46_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5658..5942)
                     /locus_tag="VQT46_001468"
     CDS             complement(5658..5942)
                     /locus_tag="VQT46_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371480.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(6554..6724)
                     /locus_tag="VQT46_001469"
     CDS             complement(6554..6724)
                     /locus_tag="VQT46_001469"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371481.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEETG"
     gene            complement(7374..8597)
                     /locus_tag="VQT46_001470"
     CDS             complement(7374..8597)
                     /locus_tag="VQT46_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET2371482.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            8765..10087
                     /locus_tag="VQT46_001471"
     CDS             8765..10087
                     /locus_tag="VQT46_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET2371483.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGAIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTTENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            10089..11975
                     /locus_tag="VQT46_001472"
     CDS             10089..11975
                     /locus_tag="VQT46_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET2371484.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYINRVFKTDIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRGHDFVP
                     ELRFEDFLDKELSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEKFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            12143..12487
                     /locus_tag="VQT46_001473"
     CDS             12143..12487
                     /locus_tag="VQT46_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2371485.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            12497..13909
                     /gene="lacG"
                     /locus_tag="VQT46_001474"
     CDS             12497..13909
                     /gene="lacG"
                     /locus_tag="VQT46_001474"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2371486.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDITLAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVLEFHQLGIEGEIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            13979..15658
                     /locus_tag="VQT46_001475"
     CDS             13979..15658
                     /locus_tag="VQT46_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2371487.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMIAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPGEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLDIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(15784..17223)
                     /locus_tag="VQT46_001476"
     CDS             complement(15784..17223)
                     /locus_tag="VQT46_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET2371488.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAF
                     FEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(17227..18576)
                     /gene="trkA"
                     /locus_tag="VQT46_001477"
     CDS             complement(17227..18576)
                     /gene="trkA"
                     /locus_tag="VQT46_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET2371489.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            18764..19612
                     /locus_tag="VQT46_001478"
     CDS             18764..19612
                     /locus_tag="VQT46_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET2371490.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            19627..20175
                     /locus_tag="VQT46_001479"
     CDS             19627..20175
                     /locus_tag="VQT46_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET2371491.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
BASE COUNT         6136 a         3435 c         4144 g         6536 t
ORIGIN      
        1 tataatatag ggagtaatct atgtatctta ttgaaatttt aaaatctatc ttcttcggga
       61 ttgttgaagg aattacggaa tggttgccga tttccagtac aggtcacttg attttagcag
      121 aggaattcat ccaataccaa aatcaaaatg aagcctttat gtccatgttt aatgtcgtga
      181 ttcagcttgg tgctatttta gcagttatgg tgatttattt taacaagctc aatcctttta
      241 aaccgactaa ggacaaacag gaagttcgta agacttggag actatggttg aaggtcttga
      301 ttgctacttt acctttactt ggtgtcttta aatttgatga ttggtttgat acccacttcc
      361 ataacatggt ttcagttgct ctcatgttga ttatctacgg ggttgccttc atctatttgg
      421 aaaagcgcaa taaagcgcgt gctatcgagc caagtgtaac agagttggac aagcttcctt
      481 atacgaccgc tttctatatc ggactcttcc aagttcttgc tcttttacca gggactagcc
      541 gttcaggtgc aacgattgtc ggtggtttgt taaatggaac cagtcgttca gttgtgacag
      601 aatttacctt ctatcttggg attcctgtta tgtttggagc tagtgcctta aagattttca
      661 aatttgtgaa agccggagaa ctcttgagct ttgggcaatt gtttttgctc ttggtcgcga
      721 tgggagtagc ttttgcggtc agcatggtgg ctattcgctt cttgaccagc tatgtgaaaa
      781 aacacgactt cacccttttt ggtaaatacc gtatcgtgct tggtagtgtt ttgctacttt
      841 acagttttgt ccgtttattt gtataagaaa aaccttgaag gggcaactct tcaaggtttt
      901 atactcttcg aaaatctctt caaaccgcgt cagctttatc tgcaacctca aaacagtgtt
      961 ttgagcagcc tgcggctagc ctcctagttt gctctttgat tttcattgag ctttaaaatc
     1021 cagtcatggt aatccccaat aggcggacac ctctttcttt cttgcttaat tcttcataga
     1081 gttgcagggc tatttggctt atctgactag catcttgtgt tttttgagca agactttttc
     1141 gtttggtaag agttgaaaag tcctcgtagc ggattttcaa aatgacaatt tttccagctt
     1201 tttcttgttg atgtagattg agagcgactt tttctgatag aagagtcagc tcttttttga
     1261 tatcttcctc agcaaggaga atcttcccgt aggttttctc cttgccgatt gatttacgga
     1321 tgcgattgga tttgactgga gagttgtgaa tgccacgagc ctttcgatac agatcatagc
     1381 ctagtctacc aaaacggtct attagggtta cctcaggaac ttcaagtaaa tcagcaccag
     1441 taaaaacgcc catttgatga agacgttcta ctgtcttttt tcctactcca tgaaatttgg
     1501 aaatatccat ttgtttgaga aaatcctcag cctgttcagg tagaatcact gtcaaaccat
     1561 gtggtttttg ataatcactc gccattttag ctaagaattt gttgtaagaa acgcctgcgg
     1621 aagcagttag atggagttct tgccagatat ctttttgaat gaggcgagca attttgaccg
     1681 ctgacttgat accgagttta ttttctgtca catccaaata ggcttcgtca atgctcatgg
     1741 gttcaatcaa atctgtatag cgcttaaaaa tagctcgaat ctggagtccc acagacttgt
     1801 atttctcata attccctgag ataaagacag cctggggaca acgttcataa gcttccttgg
     1861 aactcatggc agaatggaca ccaaaagctc ttgcctcata actacaggta gaaacgactc
     1921 cccgtccacc tgtttgccga gggtcgcttc caataatgac aggttttcct ctgagtttag
     1981 gattatccct gatttccact gcagcaaaaa aggcatccat gtcaatatgg atgatttttc
     2041 ttgacaaatc atttaacaaa ggaaaaatca acatgcctag caccttttta tactcttcga
     2101 aaatctcttc aaaccacgtc agctctatct gcaacctcaa aacagtgttt tgagcaatct
     2161 gcggctagct tcctagtttg cttttcgatt tccattgagt gttactgctt attttctttt
     2221 attataccct tttttctgaa aaaaagaaaa aaggacttta ttttttcaaa aatataatac
     2281 agtttgaaat aaaatataga ctgttttaga aaagaaagtg taaaaatagg gaattttcac
     2341 ttgttgaaat cggttactat atggtatact tgtcttatga atgtaacaga tgactgttac
     2401 tagaaaaaag aggacattaa tatggttgtt aagacagttg ttgaagcaca agatattttt
     2461 gacaaagctt gggaaggctt caaaggcgta gattggaaag aaaaagcaag tgtatcacga
     2521 tttgtacaag ctaactacac accttatgat ggagacgaaa gcttccttgc aggaccaaca
     2581 gagcgttcac ttcacatcaa gaaaattgta gaagaaacta aagcacacta cgaagaaact
     2641 cgtttcccaa tggacactcg tccaacatct atcgctgata tccctgctgg atttatcgac
     2701 aaagaaaatg aagttatctt cggtatccaa aacgatgaac tcttcaaatt gaacttcatg
     2761 ccaaaaggtg gtatccgtat ggctgaaact actttgaaag aaaatggata cgaaccagac
     2821 ccagctgttc acgaaatctt cactaaatat gtaacaacag ttaacgacgg tattttccgt
     2881 gcctacactt caaatattcg tcgcgctcgt cacgcacaca ctgtaactgg tcttccagat
     2941 gcatactcac gcggacgtat catcggtgtt tacgcacgtc ttgctcttta cggtgcagac
     3001 tacttgatgc aagaaaaagt aaatgactgg aatgcaatca aagaaatcga tgaagaaaca
     3061 atccgtcttc gtgaagaagt aaaccttcaa taccaagcat tgcaacaagt tgttcgcctg
     3121 ggtgaccttt acggggttga tgttcgcaaa ccagcgatga acgtgaaaga agcaatccaa
     3181 tgggttaaca ttgctttcat ggctgtctgc cgtgtgatta acggtgctgc tacatctcta
     3241 ggtcgtgtac caatcgtatt ggacatcttt gcagaacgtg accttgctcg tggtacattt
     3301 actgaatcag aaatccaaga attcgttgat gatttcgtta tgaaacttcg tacagttaaa
     3361 tttgctcgta caaaagctta tgaccaattg tactcaggtg acccaacctt tatcacaact
     3421 tctatggctg gtatgggtaa cgacggtcgt caccgtgtta ctaagatgga ctaccgtttc
     3481 ttgaacactc ttgacaacat cggtaactca ccagaaccaa acttgacagt tctttggact
     3541 gacaaattgc catacaactt ccgtcgctac tgtatgcaca tgagccacaa acactcttct
     3601 atccaatacg aaggtgtaac aacaatggct aaagacggat atggtgaaat gagctgtatc
     3661 tcatgctgtg tgtctccact tgatccagaa aatgaagaac aacgccacaa catccagtac
     3721 ttcggtgctc gtgtaaacgt tcttaaagcc cttcttactg gtttgaatgg tggttacgac
     3781 gatgttcaca aagactacaa agtatttgat atcgaaccaa tccgtgacga agttcttgaa
     3841 tttgaatcag ttaaagcgaa ctttgaaaaa tctcttgact ggttgactga cacttacgta
     3901 gatgccttga acatcatcca ctacatgact gataggtaca actacgaagc tgttcaaatg
     3961 gccttcttgc caactaaaca acgtgccaac atgggattcg gtatctgtgg atttgctaac
     4021 actgttgata cattgtcagc tatcaaatac gctacagtta aaccaatccg tgacgaagat
     4081 ggctacatct acgattacga aacaatcggt gactacccac gctggggtga agatgaccca
     4141 cgttcaaacg aattggcaga atggttgatc gaagcttaca caactcgtct acgtagccac
     4201 aaactataca aagacgcaga agctacagta tcacttttga caatcacatc taacgttgct
     4261 tactctaaac aaactggtaa ctcaccagtt cacaaaggtg tatacctcaa cgaagatggt
     4321 tctgtgaact tgtctaaact tgaattcttc tcaccaggtg ctaacccatc taacaaagct
     4381 aaaggtggtt ggttgcaaaa cttgaactca ctttctagcc ttgactttag ttatgcagct
     4441 gacggtatct cattgactac acaagtatca cctcgcgctc ttggtaagac tcgtgatgaa
     4501 caagttgata acttggtaac aatccttgat ggttacttcg aaaacggtgg acaacacgtt
     4561 aacttgaacg ttatggactt gaacgatgtt tacgaaaaaa tcatgtcagg cgaagacgtt
     4621 atcgtacgta tctctggata ctgtgtaaac actaaatacc tcactccaga acaaaaaact
     4681 gaattgacac aacgtgtctt ccacgaagtt ctttcaatgg atgacgcctt ggatgcattg
     4741 agctaatcaa gttcttgaat aataaaaagg aaccctcggt caaacgactg agggttttgt
     4801 gcttgggata gtatgagcaa ttccttcggc gcaatatgca atgtttttgg gaaggaatag
     4861 tggaccgaat ctgaaatata atagattgaa actagaatag tacaccttta cttctaaaac
     4921 attcttagaa atcgatttga ctgtcctgat cgatttgtcc tattcttatt tcattttact
     4981 atagtccgct gaaacggctc aaacagtgct agaaattgac tggaattctc taagtgattt
     5041 gttccgattt tatttcattt catcataaaa ataagatgac tggctaattg acaatcatct
     5101 tgtttgatac tgttaataaa attcgcgaag tttatcttga ttttctttaa aaaatttttc
     5161 taaccaatcc ataccataag cataactaaa accttctaat agaacagaga ggtcaatagt
     5221 atcaaatccc atgtctttta aatatttaaa ggtatcgaat ggtgaatgaa agtttttgta
     5281 tttaataatt gcaccaatat cttgcaaatc ctgctctctg atactcatca tcttcattcc
     5341 taacacatac tcaataggga ctactaaaac ggtcagattc tcaaatgagt acaaggattc
     5401 gcataaactt aagggaggtt gtttgttcat atttgctttg caacatgatt gttgagccat
     5461 aactcttcgt ggatgttaag attaaactgt tttcctacac gagcaataat ttcattgatt
     5521 ttctgatttt ggtcataaaa agcatcaaca tcttgtgtgg cacgtaaacc atgatattct
     5581 aagacataac cataattgtt aaagtcagat tttcctgaat taatttctta tttagggctt
     5641 ggaagaccgg tttcatttta tccatgtttg tatttctcca tcaatttttg aacattggtt
     5701 aacttagcag gtttatttaa tgaaatcaca tatttatgag ttggagtatg ctcttgaaag
     5761 gcatacttca agctaatttt ttgaaaacgg gttagttctt tggagtctag caacttttct
     5821 acatcttggt ttgttaaata agaatagtct tcaaaaataa cttttcgcaa atagcgaaac
     5881 caatggcttg cgttgaattg tgattgtttg gatgcctgta tcatataatc gtaccaatcc
     5941 attgtcttcc tcctataaaa tttagtttat attattgtag tttatattca aaaatgtagt
     6001 ttttcttaat tagctcgtat ctataggatg atactgaaaa tcttcttgtt gctttaaatc
     6061 acaatcgaaa aattctgttt ttcatcttag aaaagaatgt ttagaaatgt aaaatgaacc
     6121 ttttttctta tccgaaaacc ttactaaagt atataattta ggcagtcaat tctgtatgat
     6181 aatgtttgta ctatcgtcga gtttttgctt gattgcctaa cgagataaat tttagaagag
     6241 ttttcggtgt gatttgacaa gtttctgact ggaaggatag ttacactagt attgtttatt
     6301 aaaatgagca gatagagaaa atttggaatc tatttgctta ttatcaatcg tttttttagc
     6361 ttatttgtct tagattggta tagaactgag ctatggatta atcttcttct atcttatcct
     6421 gttcctaaat atgttggtag aaaaatgaag cagttgttac gagtgtctgt attgggaaaa
     6481 attttgtcta tagaattctt taaatgatat gaaggctagg aatgccaaaa cactgacata
     6541 tttcgtttaa agtctatcca gtctcttcaa ttgtatttgt agaaatgcta tcagtaatat
     6601 attcgcgaac actatgattt acaacagtgt ggtcgtacat ctttgtaact ttattataca
     6661 acaaccattt acaggtgtaa agttgagcag tgtctttagt aaatttaggg acttgttttg
     6721 tcatagtttt gatacctgta ttcgttgttt catgagcatt tgacgtttct tttcatgtag
     6781 gcatttcaac aattagaatg atatttttcc gaggatgaac ttatatattg tgacttttta
     6841 gagttatgat gcctcttgat ttgactaccg ctatcaattt catccacttt tacagtttca
     6901 tggttttatg aaccgaaaca tctaggtaca ggttttagca tcaattgatt gtttttgagc
     6961 catatgaagt tgaaacgtgg agatgctttt cttgtgataa cgccctattc aaagaggaat
     7021 aaccgttttt ggagagagtt cagtactatg tggcgctaaa tactatatgt aaaacatata
     7081 ttaaacaaga tttaactaag gagaattgta aaaacaaaaa tgagaatttc atataaagtt
     7141 tattctagga gtatgtatct tgaataaaaa tcgttattta agttcagggt tatgatgaat
     7201 gtttttataa taataaaatg cagctagaag aaaagttatt ttaatataaa tcactcaaca
     7261 tagagagaag gcggtttcct atatggaagt cgtcttgttt tcatattgtc taaatacgag
     7321 atatctacta caggttatag ttgatttaaa caggtctata gatttctaat atattaaggt
     7381 gaaataatat cttgtaatac attgctatgt tctatgaaaa aagcgacgat agctaatgca
     7441 caagctccta tacttccacg atgtttgttg taaggtaaaa tttcaatttc tatattacga
     7501 gtaaagggaa cgaagtggag ctggtcttgg attttatccc tgacttcatg agtgaaaggt
     7561 tgataattaa gcaattgact gttgatatag attttatcag caggattgat gaggaggaga
     7621 tttgcaatag aagtggctaa taaattgact cctttatcaa tttgttgacg taaagcggag
     7681 tcgcctaaat tataagccgt taaaagggtg tctaaatgaa tgtctttttc agtctttaca
     7741 aggcttttta gtacagttag ttgggaattt ttaaataata attgggcgtg tttgattaac
     7801 caagcatccg aaatatatgt ttgtaaacaa cctttttttc cgcattcaca atattgccca
     7861 ttcaattcga caatggtgtg tccaatttct ccgatataag gatttttaga ggctcctatt
     7921 ttttcttttg tgaaaaagga agtgtaaata cctaatccag cgtgtaggaa aataaagtta
     7981 tcgggggtat tgtgtggatt aaaaaggtat tgtcctatag ccatacaatc gatattattt
     8041 tttacaataa aaggaaaatt gaatctttta attacattta ataaattaaa agattcccat
     8101 atggggttgt ttgtaatgat acttccggag tctttgttat aatgtccagg tattgataag
     8161 ccaaatccaa gtaattttgt ttccaaaggg acgtactcta tagctgtttt tatcatattg
     8221 gtaatggtgg aattgatttc tgaaatagga taatcttcat tcaaaatttc tgtctcgaaa
     8281 agagttttcc cttgtaagtc acatagactg agaaagatac ctaggacgtt tatttcaata
     8341 cctccaacaa catacggaat attatctgtg atagaaatag tttttctacg tcttccagat
     8401 ccggaaaact cgctaaattc atcaccagtt tcgtatatga gggactgttc gcttagctct
     8461 tttatgatgt tagtcgttgt tgctggagta agtcctgttt cattaacaat atctgtacgg
     8521 gatgttgctg gatttcgata tagaaactcc agtatagtgg ctctattttg taaaaaggct
     8581 gattgttttg taatcatttg tttcctcctt tggtttattt tatattaaac ataagaaaaa
     8641 atcaattaaa attattattt tatacaaaga aaaaaatatt gtaaaaacaa caaaaaatat
     8701 attgacaacg ctttctgtta gtggtatatt taatttataa aaaataaaaa aaggagttcc
     8761 ggtgatgaac aatattttag cgtttttaga aacaaaagtc gctccgtttg gtgaaaaagt
     8821 tggcaaccaa cggcatttga aagctattcg tgaaggattt atgatggcaa tgcctttgat
     8881 tttagtcgga tctttatttc ttattctaat cagttggcct caagaggatt ttacaaattg
     8941 gctgaatagt gttggattgc taagtatctt gacaactatg aatcagtcaa cagtagcgat
     9001 tatctccttg gtcgcttgtt tcggtattgc ctacaggttg tcggaaggat atggtacaga
     9061 tggtccgtcg gcagggatca tagccttatc cagttttgta ttgatggcac ctcgtttttc
     9121 gagtatggtt tatgataaaa atggggagca ggtcaagcag ttatttggcg gcgcaatacc
     9181 attttctagc ctgaatgcat cttctttgtt tatggcgatt actattggat tggttacagc
     9241 agagatttat cgtatgttta tccagcgcgg aattacgata aaaatgccaa gtggtgtccc
     9301 agatgtggta agtaaatcat tttcagctct tttacctggc tttactactt ttgttttgtg
     9361 ggctctggtc ttaaaaggtc ttgaagcggc aggagttgca ggaggtctca acggactcct
     9421 aggtgcaatt gttggaacac cgcttaagtt aattgcagga acgcttccag gtatgattct
     9481 atgtgttatt gtaaactcat tcttttggtt ctgtggagtt aatgggggac aagttttaaa
     9541 tgcttttgta gatccagttt ggttacaatt tactacagaa aaccaagaag ctgtggctgc
     9601 aggacaaaca ctccaacaca ttattacatt accgtttaaa gatttatttg tatttattgg
     9661 tggcggtgga gcgactattg gtcttgcgat ttgtctcttc ctatttagta agagtcgtgc
     9721 gaataaaaca ttaggtaagc tagctattat accgtctatt tttaatatca atacagctat
     9781 tctatttacg tttccaacag ttttaaatcc gattatgctg attccgttta ttgctactcc
     9841 tacaatcaat gccttaatta cctatgtatc aatggctgta ggattagtac cctacacaac
     9901 aggtgtaatc cttccgtgga caatgccacc gatcatagga ggcttccttg cgacaggagc
     9961 tagttggcga ggagctctat tacaagttgt tttgattttg gtttctgtag caatttatta
    10021 tccattcttc aaaattgcag ataaacgcaa tcttgaaaaa gaaaaagcta ctgttggagg
    10081 gaaataagat ggttatcaga gtatttgatc agcagaaaaa tacttattct agctttgcct
    10141 tagaggaatt aagttactat ataaatcggg tctttaagac tgacatagaa cttgtcgagg
    10201 agaaggaagc ggatattttt gtaggattag tcaataaaga ggatagaaaa gaccatgttc
    10261 ttatctcatt agacaagggt aaggggagaa ttgagtctaa tacaattgta ggtttgctta
    10321 ttggaattta ccgaatgttt catgaatttg gggttgtgta tactagacca gggcgcggac
    10381 atgactttgt tccagagtta cgatttgaag attttttaga taaagagcta tctatagatg
    10441 aaacagccag ttactatcat aggggagtat gtatagaggg agcagattca tttgaaaata
    10501 tactagattt cattgattgg ctacctaaga ttgggatgaa cagttttttc attcagtttg
    10561 aaaatcccta ttcttttttg aaacgttggt atgaacatga gtttaatcca tacctaaata
    10621 aagaaaaatt ctcaaatgaa ttagtacaag aattgagtga taggttggat aaagaattgc
    10681 aaaaaagagg tcttattcat catcgtgttg gtcatggatg gacaggtgag gttttaggtt
    10741 actcttcaaa atttggctgg gaatcaggtc ttagtatttc agaggagaag aaaccctatg
    10801 tcgctgaaat aaacgggaaa cgagaattat ttaatacggc tccgatttta accagtctgg
    10861 atttttcaaa tccagatgtg gcggataaga tggtagaaat tatcaaggat tatgccaaga
    10921 aaagacctga tgttaactac ttacatgtat ggttgtcgga tgctcgtaat aatatttgtg
    10981 aatgcgaaaa ctgtagacaa gaattggttt cggatcagta tattcgtatt ctcaatcaat
    11041 tggatagggc tttaacgagt gagggattag atacaaagat ttgttttctg ctttaccatg
    11101 agttgttatg ggcgcctcag aaagaaaaat tagataatcc tgaacgcttt accatgatgt
    11161 ttgcaccgat tacaagaaca tttgaaatga gttatgcaga tgtagatttt gacaattcca
    11221 tacctacgcc taaaccttat ctgcgtaata aaattatact tccgaattct cttgaggaaa
    11281 atttatctta tctttttgag tggcaaaaaa catttaaagg agatagtttc gtatatgact
    11341 atcctttagg gcgtgctcat tatggcgatt taggctatat gaaaattagt caaaccattt
    11401 acagagatgt atcttatctt tctaacctac atttgaacgg ttacatttcg tgtcaagaat
    11461 tacgtgccgg attccctcat aattttccta attatgttat gggggaaatg ctctggaaga
    11521 agacaagaag ttatgaagaa ttgattgaag aatacttttc tgctttgtat gggtcaaatt
    11581 ggcagtctgt tgttgaatat ttagaaaaat tatccagtta ttcctcatgt gattatttta
    11641 atgcaattgg cagtcgtcaa aatgatgttt tagcgaatca ttattatata gcttacaatc
    11701 tagctgataa ttttttgcca attattgagg aaaatatttc taagttatta aatagtcaaa
    11761 aggatgaatg gaaacagctc agttatcatc gtgaatatgt tgttaagatg gcgaaggctt
    11821 tatatcttca agcaaccgga aaaacaaggc aagctcaaga tgaatggaga aatgtgttga
    11881 attatatccg tgggcacgaa ttgctatttc aatctaattt ggatgtttat cgtgtaattg
    11941 aagtagcaaa aaattacgct ggtttccact tataaatcat aagtatagaa aatgaaccaa
    12001 ggtattcaga gaagattgat cctaaatatt atgaaattta aggattttta agatatttag
    12061 ggtcgacttt ctatttatat cgtagcgaag tcattttaat aatgatgtgt aaaagatgga
    12121 tcaagattga ggaggaagaa agatgaaatc aaaagaagaa ataaatatgc ttggttttac
    12181 aattgtcgct tacgcaggag atgcaaggtc agatttgatg gatgctttgg cgtttgcgag
    12241 agatggatat tttgaacagg caagagaatt ggttgagtct gcaaacgact caatagtgtc
    12301 tgcccatcga gaacagacta atttattagc ggaggaggca tctggagata attttgaagt
    12361 gagttttatc atgattcatg gtcaagatac cttgatgaca acgatgctat tgtatgatca
    12421 ggtcaagttt tttattgatg aatatgaacg aattcgaaag attgaagaac atattggttt
    12481 gcaatgagga ttagtcatgg aaaatttaca ggttaaagcc ttaccgaagg agtttttatt
    12541 aggagctgct accgctgctt atcaagtaga gggtgcaact agggtagatg gcaaaggaac
    12601 aaatatgtgg gatgtttatt tgcaagaaaa cagtccgttc ttaccagatc cagctagtga
    12661 tttttattat cgttacgaag aggatataac tttggcggca gaacatggtt tgcaggcttt
    12721 gcgtttatct atttcttggg ttcgtatatt tcctgatata gatggggagc ctaatatatt
    12781 agctgttcgt tattaccata gagtctttca gtcttgctta aaacataatg tgattccgtt
    12841 tgtttcttta catcattttg attcgcctca gaaaatgtta gaaacagggg attggttgaa
    12901 tagagagaat attgatcgtt tcatacgata tgctcgcttt tgtttccaag aatttacaga
    12961 agtcaagcat tggtttacaa tcaatgaact gatgtctctt gctgcaggtc aatatatagg
    13021 aggtcagttt cctccaaatc atcattttca attatctgaa gcaattcaag cgaatcataa
    13081 tatgttgttg gcgcatgctc ttgcagtcct cgaatttcat caattaggaa ttgagggaga
    13141 gataggttgt attcatgctt taaagccagg ctatcctatt gatgggcaaa aagaaaatat
    13201 tttggcagct aaacggtatg atgtttataa taataaattt ctattagatg gaactttttt
    13261 gggctactac agtgaggaca cgctttttca cttgaatcaa atattggaag ctaataattc
    13321 tagctttatt attgaagatg gtgatttaga aattatgaag agagctgcag ctcttaatac
    13381 gatgtttggg atgaattatt atcgttcaga atttattcgt gaatacaaag gtgaaaatag
    13441 acaagaattt aattcaacag gaataaaagg acagtcttct tttaaattaa atgctctagg
    13501 tgaatttgta aaaaaacctg gtattccgac aacagattgg gattggaata tttatcctca
    13561 agggttattt gatatgttgc ttcgtatcaa agaagaatat cctcaacatc cggtcattta
    13621 tttaactgaa aatggtacag cccttaaaga agttaagcca gagggcgaga atgatattat
    13681 tgatgacagt aagagaatcc gttatattga gcaacattta cacaaagttt tagaggctcg
    13741 agatagagga gtcaatattc aaggctattt tatatggtct ttgcaagatc aattttcttg
    13801 ggcgaatggc tacaataagc gatatggtct tttctttgtt gattatgaaa cacagaagag
    13861 atatattaag aaaagtgctc tttgggtaaa agggctaaaa cggaattaag gttagcgatt
    13921 tgactgatgt ttaatatatt ttaactatga gcttaaattt tttacaggag gagtttttat
    13981 ggataagtta gtcgctgcca ttgaaaagca acaagggaaa tttgaaaaaa tttctactaa
    14041 taattatatg atagctatta aagatggatt tattgctact atgcctttaa ttatgttttc
    14101 aagctttttg atgattatta ttatgattcc taaaaatttc ggagtagagt taccgagtcc
    14161 agctattgcc tggatgagga aagtgtatat gctaaccatg ggagttttgg gtattattgt
    14221 ttcagggaca gttgcaaagt cattggctgg aaatgttaat agaaaaatgc ctcctggaaa
    14281 ggtaataaat gatacttctg caatgttggc ggccatatgt ggctatcttg tattaactgt
    14341 aacgcttgta gttgatgaga aaacgggatc tacaagtttg tcgacaaact atttaggatc
    14401 tcaaggattg ataacttcgt ttgtcagtgc ctttattact gtaaatgttt accgattctg
    14461 tattaagcga gacattacta ttcatttacc taaggaagtt cctggggcta tatcacaagc
    14521 ttttagagat atttttcctt tttcttttgt tttacttatt agtggtttgt tagatattgt
    14581 atctcggttt agtttagatg ttccttttgc ccaagtattt caacaactat tgactcctat
    14641 ttttaagggg gcagaatcat atcctgctat gatgttgatt tggtttatgt gtgctttgct
    14701 ttggtttgtt ggaattcatg gaccatctat tgtcttacct gctgttacag ctttacaact
    14761 gagcaatatg gaagagaatg ctcaacttct tgcaaatggg cagttccctt atcattcttt
    14821 aacacctaat ttcgggaatt atatcgctgc tattggagga acgggggcta cctttgttgt
    14881 accatttatt ttgattttct ttatgcggtc taaacaatta aaatcggtag gtaaagctac
    14941 aattactcct gttttatttg cggtaaatga acctcttcta tttggtatgc ctgttatttt
    15001 gaatccctat ctttttgtcc cttttttgat gactccacca gtgaatgtat ttctaggaaa
    15061 ggtatttatt gatttctttg gaatgaatgg attttatatc cagttacctt gggcctttcc
    15121 tggtcccttg ggattgttaa ttggaacgaa ttttcaactt atctcctttg tatttttatc
    15181 tttgatgtta gttgtcgaca tattgattta tttgccattc tgtagagcgt atgatagaca
    15241 gttactggtg aaagaagata ttgcaagctc aaatgatatt attttagagg aggatacaag
    15301 tgaaataatg cctggtgaga tagatgtaat aaaaagtaag gagttgaaag tactggttct
    15361 ttgtgcaggg tctggaacaa gtgcgcaatt agccaatgca attaacgagg gcgctcaatt
    15421 agcagaagtt agagtgattg cgaattcagg agcgtacgga gctcattatg atattatggg
    15481 tgtttatgat ttaattattc tggccccaca agttcggagt tattatagag agatgaaggt
    15541 ggatgcagaa agattagata ttcagatagt tgctaccaga ggaatggaat atattcattt
    15601 aacaaagagt ccaagtaaag ccttacaatt tgtattggag cattaccaag ctgtgtagta
    15661 agtttttcca tcttttattt gagtaaagat tttgcttaca gataggcttg gatttaaaaa
    15721 cgttccccct tttttaatat aagaatccct ctttcacaat tgtaaaaaga gggattttgt
    15781 attttatctc ttagaccaag ttctcttcat aaagagaagg aggattgggt aaatctccaa
    15841 gcgccctgca atcattgcaa aggataggag aatttttgag atgggactaa agattgagaa
    15901 actagaagtg gttcctagaa taggcccgat attattgaaa cagctaaaga cagcgctggt
    15961 cacgaccaga aaatcattgc tatctaggct gacaataaag ataagcgcta gcaaaatcat
    16021 agcatagatg acaaagtact tgagaatctt atgctgggta tctttgtcaa tcaccgtttt
    16081 attaacatgg agggtcaaaa cacggtgggg cgataggatt gacaaaattt ggtttttggc
    16141 aatttttgaa aggatgaggc ctcgaataat cttgagtcca cctgcagttg atccagcaga
    16201 gccaccgatt gccatgagga aaaggaggat aaactgggag aagaggggcc agttggtaat
    16261 atctccatat ccaaaaccag ttgttgtaat gatgttggaa acctggaaga aggtcatttc
    16321 aaagctcttt gaaaaccctg ggtagaggta gagggtgttg aggctaatca agcctgtaga
    16381 aaccagtaca atgaccaagt aagccctaag ctcttcatct ccaaagaagg ccttgatgcg
    16441 acggagcatg aggtagtagt agaggttgaa atttactcca aaaaccagaa ctccgatact
    16501 gaccagatag gtaatcagtg agctgccata gtgggcaatt ccgtcgttat agacggtaaa
    16561 gcctccagtt cccgctgtcc ccatagcaat gacaaaacta tcgtagagag gcataccagc
    16621 tagataatag atgatgacaa agagggagaa gagagctaga taaaggagat agagaatctg
    16681 ggcagtgttt tttagtttgg atacaacctt gccaaaaaca ggacctggaa cctcagcctt
    16741 catcacctct aggtggctat ttttggcatt gtccataata gcaagtgcaa aaacaagcac
    16801 tcccatccct ccaatcaagt gggtaaaact tcgccagaag aggagggaac gactgagaac
    16861 tgaaacgtcg ttcaaaatac ttgctccagt agtcgtaaag ccggaactaa tctcaaaaaa
    16921 ggcatcaata aggctgggga tttgcccaga aaagacaaag gggagaccac caaagaaaga
    16981 ccaaaggatc caacagaggg caacgatcaa gactccctcc ttggcataaa tccgttgatt
    17041 ttttggcttc tgtaaactcc ctgaaccgcc taacaatacg agaatcccta tggtcgaaaa
    17101 gagggctgta aagacttggc tcgattcacg gtaatagaca gcgatagcca caggaaccaa
    17161 gaggagaaca gcttcaatca aaagtaactt tgaaaggagg taacgaatca tacttttatt
    17221 catttcttac ctcgcaatca agtcataaat cttggtgatg tttggcaaca aggttgttac
    17281 taggagcttg tctccaactt ccaacatatc ctccccagtt gggaaaatag tcttgccctt
    17341 tcgaataatg gctgcaataa gaaccccttt tttcaatttc agttgagaaa gaggtttggc
    17401 agtcatttta ttggcttcct tgatatggaa ttgcagggtt tcgatttggc cattggctag
    17461 atggtgcatg gcttgaaggt ctgaatactg ggcattaact cgaccacgaa taaagtgcat
    17521 aatcgtatct acagcgatgc ttttaggtgt gatgatactt gaaaaatcag gcgcattgat
    17581 aatctcgagg agactggtac gattgacctt agtaatattt ttctgtacac ctaccctgtc
    17641 aaggaacata gatgtaatca gattttcctc atcgactcct gttagagtcg caacggcatc
    17701 atagtgttga gcactttctt ccagcaggat atcttttgcg gttccatctc cttgaacgat
    17761 gtagagattt gggaatttct cgctaaagaa gctggcgatt tcaggattga tttcaatgac
    17821 ttttgtatcg atacgactat ctttgagaat accaagtaga taataggcaa ttctacctgc
    17881 cccaacgatg agaaggctct tcacggcgcg tgatttaaaa taattatgga agagtatcat
    17941 atcgacacgg ttaccagtga caaagattct atctttatcc tgtacagtca tgtcaccgct
    18001 tggaatgata atttgatgat ccctctctat cgcacagaca atgacattac caaatttttt
    18061 acgaaaatca gaaatgggca tttggcaaag accgctggtg gacttgacga caaattccat
    18121 gaggctaacg cgtccaccag caaagcgttc gacagacagg gcgttgggga agtcaatgat
    18181 attcgcgata gcacgggcag ccaagagctc aggattaacg ataagagaaa aaccgagaat
    18241 attcttttcc ttgaaataag agttagaata ttcagggttc cgcacccgaa cgatagtttc
    18301 tttagctccc attttcttgg ctagaactgc tgcaatcatg ttgacttcat cgtgctcagt
    18361 cagggcgata aagatatcac aatcttggac gctggcttgc tcaagaatgg caaaatcggc
    18421 cccgttacca aggataccaa tgatatcaaa gcgactgaca atatgattga gaacagcttc
    18481 gtcttgctca atcagcaaaa catcatgctt ttctgcaacc aaggagcgac agagggcaaa
    18541 accaactttt ccccctccga caaggataat tttcataata aaacctactt tttcatgatg
    18601 taactatcat accctttttc aagaaaaaat gcacctacta gctaataaca agagctttta
    18661 gtgaaaattc gctataagat aaaactatac cctaaccaat tgaaatagct attagcgact
    18721 ttctctgaaa tatggtatga taaaggatat acaaggagat aaaatgaata ataatttact
    18781 ggtattacaa tcagactttg gtctggttga tggtgcggta tcggctatga ttggagtggc
    18841 tttagaagag tctccaacct taaaaatcca tcacttgacg cacgatatca cgccttataa
    18901 tatttttgag gggagctatc gtctctttca gacggtggat tactggcctg agggaacgac
    18961 gtttgtatcg gttgtcgatc caggtgtcgg ttcgaaacgt aagagtgtag ttgccaagac
    19021 tgcaaaaaat caatacattg tcacgccaga taatgggacg ctttccttta tcaagaaaca
    19081 cgttggcatt gtagccattc gtgagatttc tgaggtggcc aataggcgtc aaaacacaga
    19141 gcattcttat accttccacg gtcgtgatgt ctatgcctat actggtgcta aactggccag
    19201 tggtcacatt acttttgagg aagtagggcc agagctcagt gtggaacaga ttgtagagct
    19261 tccagtcgta gcgaccatca tagaagatca tctggtgaag ggagccattg atattctgga
    19321 tgtgcgtttc ggttcgcttt ggacctctat cacacgggaa gaattttaca agttggaacc
    19381 agaatttggt gatcgttttg aagtgaccat ctatcatgct gatatgctgg tctatcaaaa
    19441 tcaggttgtc tatggcaaat catttgcaga tgtgagaatt gggcaaccca tcctttacat
    19501 caactctctc tatcgtttag gtttggctat caaccaaggt tcctttgcca aggcctataa
    19561 tgtaggtgtc ggttcatctt ggaccattga aataaagaaa atagaaggat aaaataggag
    19621 aatagtatgg aaatcaaatt tacaattaaa caagttgttg ctgtcggaat tggcgctgcc
    19681 ctctttgtcg tcatcgggat gatcaacatt ccaacccctg ttccaaatac aagcatccag
    19741 cttcagtatg cggtacaagc gctactttct attatttttg gaccgattat cggtttgctt
    19801 gttgggttga ttggtcatgc aatcaaggac tctcttgttg gttatggtct atggtggact
    19861 tggattatcg ctagcggact ctttggttta gttgtgggac tttttagaaa gtacgttcgc
    19921 gtgatcaatg gtgtttttga ctggaaagat attcttattt ttaacctcat tcaactactt
    19981 gcaaatgccc ttgtttgggg tgtcttggca ccacttggag atgttgtgat ttatcaagaa
    20041 gcggcagaaa aagtatttgc acaaggaatt gttgcgggaa ttgccaatgg tgtatctgta
    20101 gctattgcag gaactcttct cttacttgcc tatgcaggaa cccaaactcg tgcaggaagt
    20161 ttgaaaaagg actaatactc aatgaaaatc aaagagcaaa ctaggaagtt agccgcaggt
    20221 tgctcaaaac agtgttttga aattgtggat a
//
LOCUS       DAVAZV010000043        19766 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVAZV010000043 DAVAZV010000000
VERSION     DAVAZV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19766
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.043"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(481..1206)
                     /locus_tag="VQT46_001480"
     CDS             complement(481..1206)
                     /locus_tag="VQT46_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371492.1"
                     /translation="MKLLKNELIKSKIFLFIIVDICIQILVILAIKTYILDISAPYSE
                     LDYNKYWYVLHALIYMPMIFPIQILYQNLREALIEDNNNGWNIMVINTNNLVKIIYIK
                     VTINIVRCFICYFVYTIFSLIQLGGMGTDMLLTNIIFPNIIFPNIMSFLLFLPIAIFM
                     QICCIRFDSILAKALPNILLILIVLITFQSDWNIFIPATYYYTEIQSTTNLGIKLLVC
                     IWIMGFEFSLLPKLIKLKEQNLV"
     gene            complement(1219..1956)
                     /locus_tag="VQT46_001481"
     CDS             complement(1219..1956)
                     /locus_tag="VQT46_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371493.1"
                     /translation="MIKLEFLKQKKSILWFVLIFPIILNALLYIDLTFRYRGYLLVHQ
                     NELALSNWQLIFKEQTIFYFSELFYLVLSLIIYEVFAVEFKNDAWLTVISLPFRNKYT
                     INSKLLITVVYTFTFWLSDYISLYVIGKAIDNSLEIGLIFFLKTFTIQLISSLMIMLL
                     YFLTLVLIRKISGIIPIGIIMMILTISIYYNDYNFKIYLPFTYLSHAFRVTESQFYMI
                     LLSNIIIIVLFYILIRKLNERSFEMKL"
     gene            complement(1949..2677)
                     /locus_tag="VQT46_001482"
     CDS             complement(1949..2677)
                     /locus_tag="VQT46_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2371494.1"
                     /translation="MAIVEIINLTKSFKDIEVIHNTSFYLNKGKVYGFVGPNGAGKTT
                     IIKMILGILKPDSGKITIFNQTVEQNSKNILSRIGLVLGPSFYGHLDAYKNLKLIANM
                     KGLSLDTERLNEYLSMVGLKDVKKKKVKNFSMGMKQRLSIAASLLGSPEILIWDEPIN
                     GLDPQGVIEIRSLIRFLQEKKGITFLISSHILSELDKVISDIIIINYGKVEFFGSCHY
                     LLQKYNCRNLEEAYLACLAGGEYD"
     gene            complement(2711..2881)
                     /locus_tag="VQT46_001483"
     CDS             complement(2711..2881)
                     /locus_tag="VQT46_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371495.1"
                     /translation="MKKVNEYVISTAASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(2924..5017)
                     /locus_tag="VQT46_001484"
                     /pseudo
     CDS             complement(2924..5017)
                     /locus_tag="VQT46_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397758.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase domain-containing ABC transporter"
     gene            complement(5010..5558)
                     /locus_tag="VQT46_001485"
                     /pseudo
     CDS             complement(5010..5558)
                     /locus_tag="VQT46_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000059560.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5639..5701)
                     /locus_tag="VQT46_001486"
     CDS             complement(5639..5701)
                     /locus_tag="VQT46_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET2371496.1"
                     /translation="MKKISKFLPILVLVMDIIII"
     gene            complement(5870..6858)
                     /locus_tag="VQT46_001487"
                     /pseudo
     CDS             complement(5870..6858)
                     /locus_tag="VQT46_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050775.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(6807..7934)
                     /locus_tag="VQT46_001488"
                     /pseudo
     CDS             complement(6807..7934)
                     /locus_tag="VQT46_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423473.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase N-terminal ig-like
                     domain-containing protein"
     gene            complement(8097..8981)
                     /locus_tag="VQT46_001489"
     CDS             complement(8097..8981)
                     /locus_tag="VQT46_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET2371497.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(9093..9947)
                     /locus_tag="VQT46_001490"
     CDS             complement(9093..9947)
                     /locus_tag="VQT46_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET2371498.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNLTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCNIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(10005..10763)
                     /locus_tag="VQT46_001491"
     CDS             complement(10005..10763)
                     /locus_tag="VQT46_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET2371499.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVYDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYALS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            complement(10825..11013)
                     /locus_tag="VQT46_001492"
     CDS             complement(10825..11013)
                     /locus_tag="VQT46_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET2371500.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(11335..11901)
                     /locus_tag="VQT46_001493"
     CDS             complement(11335..11901)
                     /locus_tag="VQT46_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371501.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKTYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(12169..13848)
                     /locus_tag="VQT46_001494"
     CDS             complement(12169..13848)
                     /locus_tag="VQT46_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HET2371502.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEGRIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCNHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKVDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIGLDNDEQVECVSLLEKRS"
     gene            complement(13940..14101)
                     /locus_tag="VQT46_001495"
     CDS             complement(13940..14101)
                     /locus_tag="VQT46_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371503.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(14785..15099)
                     /locus_tag="VQT46_001496"
     CDS             complement(14785..15099)
                     /locus_tag="VQT46_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371504.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(15065..15454)
                     /locus_tag="VQT46_001497"
     CDS             complement(15065..15454)
                     /locus_tag="VQT46_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2371505.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(15842..16636)
                     /locus_tag="VQT46_001498"
     CDS             complement(15842..16636)
                     /locus_tag="VQT46_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371506.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(16636..17643)
                     /locus_tag="VQT46_001499"
     CDS             complement(16636..17643)
                     /locus_tag="VQT46_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2371507.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(17643..18650)
                     /locus_tag="VQT46_001500"
     CDS             complement(17643..18650)
                     /locus_tag="VQT46_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET2371508.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLATFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(18640..19665)
                     /locus_tag="VQT46_001501"
     CDS             complement(18640..19665)
                     /locus_tag="VQT46_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET2371509.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVISDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
BASE COUNT         6377 a         3631 c         2618 g         7140 t
ORIGIN      
        1 tggacatttt gaactaaaat taatttatta aacatatctc ataagcatat ctattatagg
       61 tgagacaata ttaagaaaga cggttaaaaa acaacctgac tccactggaa ttcaggaatc
      121 aggtcgctta agattttata ttattttact gtctacttga cagggagctg ttcaccaatg
      181 ggaatctata gctttttttg tgactgagaa ctattttatc tcagacttct tcaacacacc
      241 ttattattgg gcacttacgg aaggttaatg aattatttaa aataaaagta aagagaagca
      301 aacagacact ctatagctgt tagacgcttt ttagagtaat aacaatttga taaagtgaat
      361 acaacttgct taattaagcg taagaaacca gaatcataaa atcaattact ttgaagtcat
      421 gactcacgtt gtattgtttc attgttaatc gtattcaatt atttaatttt cgagcaacat
      481 ttaaactaga ttttgttctt tcaattttat tagttttgga agaagggaaa attcaaatcc
      541 cataatccag atacaaacta ataatttaat acctaagttt gtagttgact gaatttctgt
      601 ataataataa gttgcaggta taaatatatt ccaatcactc tgaaacgtga ttaaaacaat
      661 aagtatcagc aaaatattag gtaaggcctt tgctaaaatg gaatcaaatc ttatacagca
      721 aatttgcata aagatagcta taggtaaaaa taacagaaat gacattatat tgggaaatat
      781 tatattggga aatattatat tggttaataa catatcagtt cccataccac ctaattgaat
      841 taaagaaaaa attgtataaa caaaataaca aataaaacat ctcacgatat ttatcgttac
      901 ttttatatag atgattttca cgagattatt agtgttaatc accatgatat tccaaccatt
      961 attattatct tcaatcaatg cctctcttag attttgatac aaaatttgta taggaaaaat
     1021 cattggcata tatattaaag cgtgtaaaac ataccaatac ttattataat caagctctga
     1081 gtatggtgcc gaaatatcta aaatatatgt ttttatagct agaatgacta gaatctgaat
     1141 acagatgtca acaataataa ataaaaatat tttactctta atcaattcat ttttaagtaa
     1201 cttcattttt attacctatt aaagtttcat ctcaaaactt ctttcgttca atttacgaat
     1261 taatatataa aaaagtacga tgattattat attagatagt aaaatcatat aaaattgact
     1321 ttcagtcact ctaaaagcat gagaaagata agtaaatggt aagtaaatct taaaattata
     1381 atcgttgtag tatatgctaa ttgttaaaat catcattata ataccaattg gtattattcc
     1441 agaaattttc cttataagta ctaaagttag aaaatataat aacattatca tcaacgagga
     1501 aattaattga atggtaaatg tttttaaaaa gaaaatcaaa ccaatctcta aactgttatc
     1561 aatagccttc ccaataacgt ataagctaat ataatcagac aaccaaaaag taaatgtgta
     1621 aaccactgta atgagtaatt tagaatttat tgtgtacttg tttctaaatg gcaatgaaat
     1681 tacggttaac catgcatcat ttttaaattc tactgcaaac acttcgtaaa ttattaaaga
     1741 tagaactaaa taaaatagtt cagaaaaata aaatattgtt tgttctttaa aaattaactg
     1801 ccaattagat aaagcaagtt cattttgatg caccaataaa taacctcgat acctaaaagt
     1861 taagtctata tataacaaag cattcagaat tattggaaaa ataagaacaa accataagat
     1921 gctttttttc tgctttagaa actctaattt aatcatattc acctccagct aaacaagcta
     1981 agtaggcttc ttccagattt cgacaattat acttttgtaa aaggtagtgg caagaaccaa
     2041 aaaattcaac tttcccataa tttataatta taatatcaga tatcacttta tccagttcac
     2101 taagaatatg acttgatatt aaaaatgtaa tacctttttt ctcctgtaga aaacggatta
     2161 aacttctaat ttcaattaca ccctgtggat caagtccatt gattggttca tcccaaatta
     2221 atatttctgg actacctaac aatgatgcag ctatacttag acgttgtttc atgcccattg
     2281 aaaaattttt cacttttttc tttttaacat cttttaatcc taccattgat agatattcat
     2341 taagtctttc agtatctaaa ctaagccctt tcatatttgc tattaacttc aaatttttat
     2401 aagcatcaag atgaccataa aatgaaggtc ccaaaactaa tcctatccta gataatatat
     2461 ttttggaatt ctgttctacg gtttgattaa aaatagttat tttcccagaa tctggtttta
     2521 aaatccctag aatcattttg ataattgtag tttttccagc cccatttggt ccaacaaaac
     2581 catatacttt tcccttattt aaataaaatg aagtgttatg aataacttca atatctttaa
     2641 agctttttgt tagatttata atttcaacta tagccatctc tactccttag tttacagcaa
     2701 aaaattatgc ttaattctta ttgtttttgt aaacaatcag cgaacccaat actattccat
     2761 tcaacaaacc taaagaaata ccatattcaa ctggaaaatc taaaaaaatt gcaaatacta
     2821 ttccaatcat cacccctagt gaggctgctg ttgaaattac atattcattt actttcttca
     2881 ttttctttac acctcatttc ctttttgtat ataagctgta gtactatcca ccaagatcca
     2941 ttaagtactt atgatttcct gactcaacaa tcttaccacc tttcattaca aaaataatat
     3001 ccgcatcctt aatcgttgac aatctatgag ctataattat ttgagtacaa tcctgacttt
     3061 gtatatactt tgttattctt tcctcattaa tagtgtctaa tgcactagtt gcttcatcta
     3121 aaattacaat actaggatta tttattaatg cacgtgccag tgctatccgt tgcctttgcc
     3181 cacctgaaat atttgacccc atctctgaga tgatagtatt aaatttcatc ggcatagcca
     3241 tgatttcatc atagatttga actgctttac aaacttcctc tatcttttgt gaagtaactt
     3301 cgttctttaa agttatatta tcaagaatac ttcggttcaa taaaaatgaa tcctgtggaa
     3361 ctactcctaa attttgactt aatatttttt tatctatttg attaatattt acaccatcaa
     3421 ataaaatttt tcctgtatca atcttatata atcctgatag tatttttgat aacgtacttt
     3481 ttcctgaccc cgattgaccg actagtgcaa ttctctgtcc tggctcaata gtcaaattta
     3541 aattttctat tacaggagct gagtctttgg aataagagaa agataggtcc ttaatatcta
     3601 ttctaccttc taaagaacac tttttaagac cattttcaac attctcttca ttttcaagcc
     3661 agatatcatt tactctattt aagtatcctg ctgccaaaat atactacgta taagcattaa
     3721 atattgagat ttctgaacta aataaaattg atgccatcgt ttgaaatgcg acaacctcac
     3781 ccaataaaat ttttccattt aaaacattat caagtccaaa aatcaatata attataggag
     3841 cgaacaattg aaatacatta gtagctgaat tgtataaaat atgcacaata cttcgttttt
     3901 tatactttgt caatacgttt tttaaatact tagaccagtt ttcatatatt tcatcttcta
     3961 atcccgatat ttttattgaa gaaatagtat ttaatgcttc tgtttctact gagtaaatca
     4021 atgattgttc ttgtaattct ctattaaccg tatcatacat tatttttcta gtactaaaca
     4081 gaaacaaaaa attgattaaa ctcaatataa gagctataat tgataatgtt tttgaactaa
     4141 gaaacatata tattacaaca cttagaatag tcccgatatc tactactccc ccaacaactt
     4201 ggttagtaaa tagctcccta aaaccactaa gactagaaat tctgtataaa atatctcctt
     4261 ttgccctgag ttcaaaaaaa ctatatggta gtttaagcaa atgcttaaat gtaaaacttt
     4321 caatatctct actaaaaaat atattagaaa atagaattcc catactccta gccaagatag
     4381 aaataaggta caaacaaagt agagaaaata aaattaaaaa cgaggtttga aaagaaaatg
     4441 tattccctaa tgcagaatta ataaactttg aagtcattac tggtacggaa agtattatta
     4501 agtaacttat tattgaaaat agtaacgtca aaatcaatcg accttttacc tttgaaaaac
     4561 tagagaatac tcttatccat ggagaaggaa actgcgactt caaagattga taattttcgt
     4621 taggaaatga tagcagtact atattactaa aatgttttga aaactcctta aactcataat
     4681 ttatatatcc tttagaagga tccattatat agaccttatt cttttttact ttgtaaataa
     4741 ctacataatg ttgattatcc cagaatgcta ttaatggtaa cggaagttca ctaattttat
     4801 ttacatcttt aacttgatat gagccagtat caaaatttcg tttattcaat aactgtttca
     4861 agtcacctat actataacca tctctccctt tttctatatc acgtcttaaa tctagtaatg
     4921 tctctttgct tttatagaaa tgtagtatgg acaagcagca acataaacca cattctattt
     4981 gagacatttg ctcaatatta ggtacttttc tagtcatcat gtcctcttaa ctccagtaat
     5041 aaaacattaa gtaatctatc atcttgtttt cgagatattt catagacaac tccagatact
     5101 cctagcataa aagaaaatgt attcatagta ttcaaatccg tacttaattc tggtttgata
     5161 acctgagaaa cgacattatc aaaataaaaa tctatagatt cttttattaa taggttttct
     5221 tcatctttca atattgcatc aagacaactg atagtaccta cagaaccgtg acataaattc
     5281 aattctctta ttttttctac attagttaat acattttcaa ttattgataa atcattattc
     5341 ccaatattag ttttatcgaa aatttctttt ctagctaata aaatgcccgg agctccataa
     5401 caccaaaaat taggaaagga atcattatga tttcttcata tgtctttcca attttttaat
     5461 atattattga aacatttatc ttctttatat agtaattcct ctatacattt taatatatct
     5521 gtactaggat taatttcata ataatatgat aattacattg ctactccaga ataatcgtgt
     5581 gctaaacctg ttactgttat attatctaat tgtgaaatac aataattaat acactttttt
     5641 aaatgatgat aatatccatc accaaaacca aaatcggtaa aaattttgaa attttcttca
     5701 tacttggact tcctttccgt ttttatttat tgtacaataa ataaaaacgg atttaatttt
     5761 tgttgggaaa atgggaaatt atgaaatcaa aacttggcat cacacttaga aaagttcgta
     5821 aaggaaaaca aattagtcta tgctctgtag cagatgaaca tctttcaaaa tcacaaatat
     5881 ctcgttttga acgtggggag tcagagatat cttgtattcg actaatcaat attttagaca
     5941 aattacatat tactttgtag gggagttttt ggctatcgtt gctcaattgt ctgattaagg
     6001 tcctaccctt gatgaaacaa ttattatcca tgttttcttt attatagaca aagtaagaag
     6061 acgtttctcg aatgtagact ttatattttt tatgattttc ttcttccata atatccaatt
     6121 gatagttggg aatgaaaata agaccgctct gtttgacacc gaaagacacc ttgatataga
     6181 cgcccttatc aactagcttc tctatttggt tctctgcaag ttccacttca aattcacgaa
     6241 cggtatctca tttttcctta aatgtcttaa aggcttcctc aatctcttca gtggatactt
     6301 tatccttatc tcgttcttct tggaaagcat ggtactgttc ctgtaaattc tctaatcctt
     6361 ctgaagcaac gacttcctta tttttaaaat aatcttgaaa aaatttgaca tcatataatt
     6421 tcttatcact tattttttga tgacccaaac ttatcttttg attattttct tccaggataa
     6481 aagttacatt ttttgtttta agtcaatggt tagattcaat tcttttgctt ttgttattaa
     6541 atcttctaaa gaattgacac ggtttaacaa aaattctaaa cgactttcaa tctcttgctt
     6601 agcaaaatgc gttctaaaaa attcttcatc atatagatct cgtttgctga gttggcgccc
     6661 tcgaattggt tttatcatcg ttctatctgt catcaaaaaa cggctatgct tttgactaaa
     6721 atcaatctga acatgcaact gctttgcttt ctctaaaaaa tcatcaaacg atttagattg
     6781 ctgaagcaaa aaataaagac gttgtttcaa ttcaaattta tgactagatt ccttatattt
     6841 tttataatct cgaaaagatc aggattttta gctaaaactg ccttacgaaa atccttccag
     6901 aactgatggt caatctcatt agccacatcc aaacgccaag catcgatatt aaactcttca
     6961 atccaataag tcgcaacctt taaaagataa ttcttgacct ctggattggc tgtatttagc
     7021 ttaggcatat agtcctcgaa accaaaaaca tgatagggta agtctctctt attaactagc
     7081 ttttcagttg tcaatgggaa ttgttgaata tggaaccaat ccttataagc agactgttca
     7141 ccatttttga cgacattttt tcattgaaga gattgcgaac caatatgatt aaataccgca
     7201 tccagcatga ctttcatgcc acgatgatgc gcttgatcca ccagttcccg aaaggtctcc
     7261 ttgtctccaa aataacggtc aatttcaaag taatctgtcg tattgtactt gtgattactt
     7321 gtagattcaa agatgggaca aagatatagt ccagtaatac ccaagtcttg caagtaattc
     7381 atatgatcaa taatcccctg taaatcacca ccaaagaaat catcgctctt aggtgtgaca
     7441 gatgaatccc agtctaaagt cccttctggg tttaatagag cattgccatt ggcaaatctt
     7501 tcaggaaata tctgatacca taccgtattt gaaacccagt caggaacctt gcaggcatca
     7561 atctcatgaa gataaggcaa cttaaatcca ttcccaattg catgaagatt ttctagagaa
     7621 ttttccacac accctttatc gccatacaaa atattttgac cttctgtatc tctgagctca
     7681 aagagatact ggatacgtgc aaagtcaact gacacttcaa cctgccaatg gtcaaataag
     7741 gtaccagaag ttatcttgac catttctttt gtatcctgat aaaactcttc cataaagata
     7801 aaagggtccc catagtgcaa gttgatgctt tcaatgtccc ctttcttagt tcgaattcga
     7861 atatggagtt tcttatcctt ataaagatag gcatactccg actcaggcct atggtaaata
     7921 gcactcaatt ccatcaattt gtctcctaaa gtattcattc aaattttacg caaacgtttt
     7981 caaactcaat aaatccagta tactattttt gtaaactatt tgcaaggaat gtccgttgtt
     8041 aaaggaacta tcttttaaag tatacaaaaa gccttaaaaa aggctttctc tatatactaa
     8101 tcctctttcg gttttgaaaa tacttctact cgctgagcta ggactttgat ttctacaggt
     8161 aggttatctg atttatctcc gtcaacatct gactccaatt cactatctga agagatttta
     8221 atattacgcg ctttgatata ctcgatatta tcatttgcga caacatcccc ttttaataaa
     8281 tcaggaatga cggataattt ggagaatata gaggcatctt tcagaatcaa aatgttggca
     8341 tagccgtcct tgttttcttc aaagattttc ttatcagcga agtaatttgt caaaaggacc
     8401 aaaacatggc tagcttcacc aacataattt ccattttctg tctcaacctt aatgttaaag
     8461 acctgatctg tcatgacaga cttcatggta tttacagcat aggttaaaat accgaatttt
     8521 gttttgtcct ctatttcaac attgtgaatc gcctcaggca gagaaccgat actaaagata
     8581 taaccaaaat agttgtcatt tgctttaccg atatcaatct tattggttaa atcaaaatcc
     8641 agttcgtcaa ttgcgccatc gatgtcttga ttgatttcca aaagttttgt aatgaggtta
     8701 cccgtaccgc ctgggataat ccctaactta ggaatgtagt ctctctcatc aatacctgaa
     8761 atgacttcat tgacagttcc atctccacca aacacaacca ctgcatcata ctgctcacga
     8821 gaagcttctt cagcaaaatg tgttgcatcc agcgcttttt cggtaatttt ggtttcaaca
     8881 tattcaaagt attcttttgc tttattctcc agcttttctt tgtaatccaa agccttctcg
     8941 ccaccagaag tagggttgat aattaccatt gcttttttca ttgattttat ccttaatttt
     9001 aaacagaaat gtttacattt cgtcgtatgc aagtaaatgt aatcctatta tacaatgaaa
     9061 atacagaaaa gagaaatctg acgtactgga gattaatacg cttttattct attttcccat
     9121 cgcctaacta catcctttaa gggttcatcc aagtaagaat aggccttatc cttgatccaa
     9181 tcaggaatac cgtaagctgc ctctgctatg ttacaagtga ttgctgcgag agtatcactg
     9241 tcgccaccaa gtgagatggc atttcttatc gcatcttcga agtctctact ttcaagaaag
     9301 gcgataatgg cttgagggac agtttcctga catgtttcgt taaaacgata gttaggacgg
     9361 atttcatcta aagtttgaga tagattgtaa tcgtattctt tttctatata atccttaatt
     9421 cgtcttttac actctgtaag attgtcgtta attgattgct cgtactctct acaataacca
     9481 ccaaagtaaa aacgacatag aaagatagca tcagctgtag ccatagcgcc tttgacacct
     9541 tctggatgat tatgagttac ctctgcagaa agactcgtaa gtcctctaga tgatggccat
     9601 ataccagttt tcgcataaaa accacagtcc atgatccaag cacatggaga aatacgcata
     9661 gctgatccat tcccaaagct attataaggc tcacggttat cgctgtttag ccatgcatta
     9721 aaccgagcac cgtaatcagc attcggatac attctgccat atttcttcat cgcgtcaatg
     9781 aaatcgtctt tttgtccacc attcataatt gcttctgcaa cagcacaggt cataaccgtg
     9841 tcatctgtaa aaaagcagtc cttccgaaat aaaggaaagt cctttgtttt gatattgttc
     9901 cattcgtaaa cagaaccgac aatatctcca ataattgctc caagcatcag attcctcctt
     9961 gttcattttg atgcttttta tattggttat ataccatatt tattttagaa aacaacatcc
    10021 tgttggattt taaaaatttc atttttttca aaatagggtt ttaccatttc tttccaccta
    10081 gctctatgaa aattgattga ttttaaagga gatagggcat aatttcccaa tgcataacca
    10141 tcatttactt caacaacaag tgttctgcca tcgcgagtaa caccgatatc tagtccataa
    10201 gctattggcg catctttcca acatgatatc gcttcatcaa ttacacttgc atcaaattgt
    10261 gcatgataat cacctgtata gggtcgaaca tctaatacgc gaccatctaa cacaaaacaa
    10321 cgccattcag ctatgaattc tacaacctca ctaatccata taggatagtc gaaaggtaga
    10381 ccaataccta ttaaatcatg ggttccatta acaactcttc cagtaaagac ttttgaacca
    10441 gctttaggct taataaattt tccccaatta tcaggtatat tcacaatctc tcctaaaata
    10501 ccagcataaa tctttcgacc ataaaactct ttaagctcaa taggatagtc ataaaccgga
    10561 acgtttaagc ccatcatttt tagtaatgct ctagtctcca ttatataatc tacaactata
    10621 tcttcacttg ttaactcttt tatttcagaa aaagattgat ataaaataac ttcttctcct
    10681 tgtaagtagg cacctacttg agcattgtat ttattaattg aaacctcact tggtaattta
    10741 ctttgtctaa tataaacaac catttcatca ctcctatatc actagtgtta cactgatttg
    10801 taaaaaataa tagcaatttt gctcttattt ttttgagtaa atagctccca taatatcatc
    10861 gaaataatca acggtattta ggagtaattc aataacctgg gactttgtta gtcgcattcc
    10921 ccttctatct ctagcatctt ctactaaatt ttcaagtttc tctagatttt tatcatccaa
    10981 gctaatcatt attctatttt tatcggttgc cattttcatc acctcaagtt aattctatca
    11041 caggtgtaac acttgtgtca actggctttt ataatacatt agtttaaaag tggagaggat
    11101 ttttaacaca gtaactttaa atctttggta ttaaaaaatt ttcacaatat ttatagaaat
    11161 aaaatctgtc tcaaatcagt tatcaaatct agtataaatt atgagcggct actctaatac
    11221 tttccctcta aacaagaaaa agacttacac tcaaggattt tcttcccccc cttcgttata
    11281 acgttttgac tcttttacta gcaaaggtat atactcacaa ggaactttgg ttgactattg
    11341 aatctctcca acttcttctt taacatatcc ttctacatct tcaatctcta caaacattgg
    11401 gtctaagtga cacaagaaat gccaaacttc gatccctttt tttctgtaaa gaatcgcttc
    11461 accgtcttca cttccgaaaa agcttctgtc gatttcatat ccgcggcttt ctaagaagtc
    11521 ttttgcttta cgatagttcg tttctcttgt ttcgacatag gttttaactt catggttgtt
    11581 aacgacatat gcatcaattt ttgaatatcc ttcgatcact ctatcatttt tgagggataa
    11641 atttgaaatc tctttccaaa taatgtttac attttcctca ggatcgaaca taaatttaga
    11701 taaaggaaca atatttccgt taaaaataat ttccatataa tccggtatgt ttttaggatt
    11761 aaaatactcc acttcaaaac catcttctgt ttccagagtg tatcccggga tttgagctac
    11821 aaaggctttc ccatcttcta tggaatcaaa tgctactaaa tctttagaat aatcattttg
    11881 gtacaattcc aatataacca tcgataatct ctccattttc attatcaggc taatgtaaat
    11941 aagcacgtca cctgaccaat tcaggctctc tgtatcatct catcatattt cctacttact
    12001 ttacgagtcc tatacccaga acacacctta tcgaccttcg gtctcacctc gttgcattgg
    12061 ctgaacatct acttttactt cgctgatgct tcaactcgta caagcagtga taccgcctca
    12121 gcgtgatgcg tcagtgggac tcaaaaggtt cggggaacct tttgaggatt aactacgttt
    12181 ctctaataaa cttacacatt caacttgttc atcattgtcc aaacctatgt tgagattttc
    12241 ttctataatt ggtagcttaa aagtaatgga ttttagccat tgtccgttag attgtttttc
    12301 ttcataaact tgaatttcag aaatcaaagc tgaaattaac tgcctacgct ctacatcatt
    12361 catgacttta tagagcttat caaaatagat cagaacctta tatatgttat ctcctgtaag
    12421 cttttcagct tcaatagtct gtttctttgc tttcgcatca attagtgatg attctaattc
    12481 atctactttg tcatacatac gatatagtct atcatctaaa tcctgtttcc ttctcttata
    12541 atgcttatct tcaacatcta aattatctat ttcctcaatt agcttaaact ttgtagaatg
    12601 actctttctc aattcctttt ggtaattatc tatttctttt tctatttcag aggtatccac
    12661 cttcatgttg attttttctt gcatcataga agcaaatttc ggattactta ctatcttgac
    12721 aatcacctct gcaacagcat catctaacaa ttcttctcta atttgcttac tgaatgtaca
    12781 cttatgacct cttatcatct gcctatggtt acaaccatag taataaaaat ctttatactt
    12841 tgtgccatct ttctttttct tgatacactt gttcccaaac attcccactc cacatatcgg
    12901 gcattttaca attccagaaa gcaagtgtgt gcgtgtatct tttcctttat tcacatgctc
    12961 atatttcttt gcttgagatt ttagcttaac ctgagcagct tgccaaactt catcggaaac
    13021 tatagcttca tgtatccctt cagatattag atattcatct tgttcaacct gcttatattc
    13081 atttcttgta ccatgaactt tttctaaagt tcttcttcca aatgctattt tcccattata
    13141 tacaggattc tttaatatct ttcttataag acctgcatca aacaaaggat tcttaccatt
    13201 ctgtcttggg atttttctaa ttccatgatt ctctaagtat ttagatatcc cattggctcc
    13261 tatcgtagta tttacatact ggtcgaaaat cgttcttatt gcaactgcct cttcctcatt
    13321 tataaacagc ttgccgtctt caagtttata tccatacgga gcaaagccac cattccattt
    13381 tccttccctt gctttttgaa tgcgaccttc cattgtttga atacggatgt tttctctttc
    13441 tatttcagcc acagctgata aaacagaaat cattagtttc ccagcatctt tagatgaatc
    13501 aatgccatct tcaacgcaga taagattaac tccataatcc tgcattatct gaagtgtaga
    13561 aagaacatca gcggcatttc ttgcaaatct tgataactta aacacaagaa caaaagatac
    13621 tccatctttt ccagatttta tatcttccat cattcgattg aactgtattc taccttcaat
    13681 agacttgcca gacttcccgg catcttcata ctctccaaca atttcataat cgttgtaaat
    13741 agcaaaagct ttcattcgtg atttttgtgc ctctaacgaa tacccctcta tctgtattga
    13801 cgtagatact cgtgtataga ggtatacttt tattttttct tttgacatag tattaatctc
    13861 aatataattt ttctatatca tatataattt ttttaattta agtttggact atcatttcaa
    13921 gtatattata acacttttat tagtccgtct caatttgtgt ttttgccatg tcaaaactat
    13981 ttttcatctc ttgatttttt gctggcgttg gatcgggtag attatctaaa tctaaagcac
    14041 cagcatattt tgcaatcaga tttgctatta aatcagccaa tccattccag tcattgtcca
    14101 atatatacct cctctaaagt tttatatcta ataattattt gtttaattaa gttttttgac
    14161 attgacaagt gctttggatt agcaacatag gaatctcacc tccgcctcta ttccggatga
    14221 gccggcttca accttagaag tatcattatc ctcattttct tcatagcgga tagggtatcc
    14281 ctccctatat tcaaactctt acttatcgct cactttcttt ttacttagca gaactttttt
    14341 tgccgaatta ttcagccgaa agatcttgac ggataggtta ttacgctcca aaaataatta
    14401 acgtcttgtc ttggtctatt caattgttaa ggttcaaaat ttatcgagag ttattaatct
    14461 ttttaaaatt tgaccatcag aaaatattta tcttaatgta acaaaattct ataaattacc
    14521 ctcttatact taacagtgaa aagaagtctt tcttggtaac caattttgaa atagaatttg
    14581 cttatataaa aaggtcaaat tcccactgca taagtagcag tgaaaattag accctcttgg
    14641 taactgtcat ctaaaagtct tctagcattt ctttaatttt ctaatcgcct ttaaagtgtc
    14701 atatttatat ttttttatct ctggcatact ttgatacctt tttagactta aagtctttaa
    14761 tagtgccttt ccacctcttt ttatctataa agattctcct acatcataat tcattttttt
    14821 atttaaacct ttctgtctta gtttgtcttt atcttcttca taccatttta agattgtcac
    14881 atagtggttt tgataggtct taccactgct ttccatgtat ctggatagtt tatttatcat
    14941 tatatctgtg tgtgagttta atttttcttt tagattttta tattcttctt tgcttaacct
    15001 tacatttttg aattctccat aaaaaatggg ggtggacttt ttatctatct ctccctctct
    15061 ctctttatct atctctatat ctttccatgt aattccaatc tggagtacct ctactgtcta
    15121 tcggtaattt aattttgata tctggcaata ctgtgctaga tatttgatct ttatattcag
    15181 tattttttaa agcttgccta ataattgaag ttaaatagaa tgctacttct ttattcaatt
    15241 ctttattttt taattttaaa caatgaattt tcatatctag gcttgcttta tatttatgat
    15301 aaaagactgc tcctaaaaat gaaacagata taaaattttc aaaaactcta taatttttat
    15361 catctatatc ttcgtagtaa cctaagatac cattgtcaat atttgtagca ctaattctag
    15421 gagtttttcc atcgagtaaa tatctttttg gaatagatga gcctgttggt acttgactcg
    15481 atttcccctt tttttcggta ataaatattt ctttttattt tgttgtctga tatttttcct
    15541 acctgtcctt tgtaggatga gtattttcta gattttcttg aataactttt tacttgaagt
    15601 tttagctttt gaactagtcg ttgtactttc tttttgttta ttatcagtcc tgatcttttt
    15661 aatattgctg ttattctcta tatcctattt ttcattcatg atattctttt actaatttta
    15721 tcttaaattc tgtgctgtat ttgccattaa aaaactgacc tcctttagtt agttttttgg
    15781 cctaactttt gagggtcagt tcaaaatttg cgacttttaa atgaattcca atattcaatt
    15841 attaagagct aacatggtgc ttgccaatag gaatcattag aggcgaattg gaaatagggt
    15901 cacgtataat ttttgcttca agattaaaga tatctttaac tagtttatca tttagtatat
    15961 cttcaggctt tccctctgca acaagtttac cttctttaat tgcaaatagg taatcagcgt
    16021 atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat ggttgtctta tatttttggt
    16081 ttagatcagt caagaggtct aatagttcta tttgatatga gatatccaag taagtagttg
    16141 gctcatctaa aagtaggata cttgtatctt gggctagggc tagagctatc catactcttt
    16201 gcctttgacc cccagaaagt tcttcaacta ggttatttgc tagatcttca acattggcct
    16261 taaccattga tctgtttatt atttcaaggt catcttttcc aagactctta aaaggctttc
    16321 tgtaggggaa acgaccacgg cttacaagat cagctactgt tattgattca gggattattg
    16381 gagattgagg taatatagct atgtgttttg ctaaatcttt ttctttataa gaattaattg
    16441 atttattatc aagcaatact tctccctcta atggctttat aagtcgagac aaggttttaa
    16501 tgagtgttga tttcccacaa ccatttgacc caataataac tgatattttt tcttcaggta
    16561 tttttatatt tatattttcc aagattattt tttcatcata accgcaggta agattatttg
    16621 accacagacc tttcattata tattcctcct gttcattttt attagtaagt atattaagta
    16681 tggtgaacct aacaagccag ttacaacacc tactggatat ctagctggta aaatattttg
    16741 agagaatatg tctgataaca aaactagtaa aattccaacc aatccagcta atattgggct
    16801 tcttttcttg ccaatattta aggctatggg accagctaaa aaagatatac aagctattgg
    16861 tcctgtaatt gaagtagaaa aagcagttaa agatacagcg caaaaaatta aaacaagcct
    16921 tgaaagctcg ggatttgctc caagtccgat tgctatttct tcaccaagtt caataatttc
    16981 tagtctttta ttaaaaaata aaactaatat agtagcaata atacttacta ttagaacaag
    17041 aggtatgtca tctaactttg taaaagataa agagccactg agccatctca taacttcttg
    17101 taattcatat cttgctactt tcaacaataa aaatgaggtg cctgctcttg tgacagcttg
    17161 aaaaccaata cctaatatta tcagtcttgc tgctgaaaaa ccatcttttt tagctagtaa
    17221 aaataatatt aaagatgatg ttagtccaca agttattgaa ataattccag tagttaaact
    17281 atttgttttt aataccaata tgcaaaagac cgctgcaata gatgaagaac ttgtgacacc
    17341 gattatatca ggacttgcaa gaggatttct taacatagtt tgaaagataa atcctgccaa
    17401 tccaaaagac cagccagcta taattcctgc taataatttt ggtaatctaa tttccataat
    17461 cgaaaaacta gctccaggaa cagtttcact atttaagact ttaatcaaag ttgaaaaaga
    17521 ataactttca tctccgataa gtaaaatgaa aaatgataga ctgattatta ttaataaaaa
    17581 tagtgaggaa aatagtgtta ttctattttt tcttttttga atacctataa ttaaattttg
    17641 cattagttat taacccctct atttttcata gttacataaa taagtactgg acccccgatt
    17701 attgcagtaa ttatccctac ttcaatttca cctggtttac ctaacatacg gccgattata
    17761 tcacatataa gcaagagctc tgcacctata aaagatgaag aaatggtcat tgtgcgtata
    17821 tctttgctta taaataagcc acaaaagtga ggaactataa gacctacgaa gccaataggt
    17881 ccaccaattg cagtaatact tgaacataaa agcacacttg caattattgc aagtgatctt
    17941 atcctattaa cattaactcc aagaccaaca gccatttcat cacccatagc taaagcgttt
    18001 aaatctgatg aaataaatat agctatcaag tgacctaaaa ttataaaagg tagtagtgta
    18061 gatatagaag ataatgtagc tgctccaagg ctacctattt gccaaaatct aaatttgtct
    18121 aagacgttat tattcggtaa aattaaaaaa cttacaaaac tgcttaaagc catactaaca
    18181 caagttcctg ataaggctag ttttataggg gtaaggcctg cttttccgct tacagcaatc
    18241 gcgtatacaa aaattgcact tactaagcca ccaatgattg caaaacttat atggcttatg
    18301 cttgatgaaa ttcctaaaaa agaaagacca attactacac taagacttgc tcctgtgttt
    18361 ataccgagta tacctggatc agctattggg tttctagtaa ctgattgcat caatacaccg
    18421 cttatggcaa gactagaacc tgctaaaatt gcaaaaatag ttctaggtat tcttttatat
    18481 ataattgatt taataaaatc atcatttgta ttgcccattc caaaagttgc taaaaaatct
    18541 ctgatattaa tttcttttgt tccaagcttt aatgacaaaa atattgtaat aagaagacct
    18601 aggcagatta caaaaattat gcctaggttt atttgttttt tatttcgcat ttttgcatgc
    18661 atttcctaaa agatttaggt attcttcaat agtatagttt attgaaagtg gtgttggagt
    18721 gcatgaggct gctaacggtg tattatctga aattacagca acggcaccat ttttaattgc
    18781 atttatttta cctaaaagag gatctttttg taaagcttca agagttttat catcaccata
    18841 agttatgatt acatcagcat catttatctt atttgcttct tctgcagaaa tttcctttgc
    18901 aaaactatct tcactctcaa attcttttaa tgattcaggg aaaactagac ctaaatctgt
    18961 taaataattt gctcttggat ctttgctagt ataaatccag aattttgatg tatctgcagc
    19021 attaatcata gtaaataata ctttttttcc tttgattttt cctttgattt ctggatgttt
    19081 ttctaattct ttggatatac gagcttcagt atttttgatt aactcatcac cttctttttc
    19141 catacctaag gcttttgaat caattttaat catatctctc cataaagttt gccaaggttt
    19201 agatttgtat gctgctacag gagcaatttt tgatagagtg tcataatctt ctttagttat
    19261 accagaataa cctgctaaga taacatctgg tttagaattt gatattgctt caaagttaag
    19321 tccatccaaa tcgtcaaata ggttagcttt accatttagt tctttgattt tttcttctgt
    19381 ccatggtaaa actcctttat cagcacttac accgtaattt gcttttgaaa atccaacagg
    19441 aactattcct aaagctaatg ctacatcatg atttccccaa gcaatagttg caactctttc
    19501 aggtttttta tctaatatag tttgaccgaa agcatgatct aaaactattt tatcaggcgc
    19561 atgctcttta gaagtatttt cttcattttt aacagaatta gaagaacaag cgctaaaaac
    19621 tatacacata gctaaaatag ctattagaaa aaatttgttt ttcataaaaa ctccttaaac
    19681 atatttcaag tctattgtat cgataataat tatcattgtc aatagataca gttacaaatt
    19741 taataatata attttttcaa aaaagg
//
LOCUS       DAVAZV010000044        19537 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVAZV010000044 DAVAZV010000000
VERSION     DAVAZV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19537
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.044"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..617)
                     /locus_tag="VQT46_001502"
     CDS             complement(<1..617)
                     /locus_tag="VQT46_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET2371510.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLEN"
     gene            complement(726..1244)
                     /locus_tag="VQT46_001503"
     CDS             complement(726..1244)
                     /locus_tag="VQT46_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET2371511.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="VQT46_001504"
     CDS             complement(1471..2340)
                     /gene="rsmI"
                     /locus_tag="VQT46_001504"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET2371512.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGTSAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="VQT46_001505"
     CDS             complement(2343..2660)
                     /gene="yabA"
                     /locus_tag="VQT46_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET2371513.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            complement(2700..3590)
                     /locus_tag="VQT46_001506"
     CDS             complement(2700..3590)
                     /locus_tag="VQT46_001506"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET2371514.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            complement(3587..4225)
                     /locus_tag="VQT46_001507"
     CDS             complement(3587..4225)
                     /locus_tag="VQT46_001507"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET2371515.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            complement(4445..5242)
                     /gene="proC"
                     /locus_tag="VQT46_001508"
     CDS             complement(4445..5242)
                     /gene="proC"
                     /locus_tag="VQT46_001508"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET2371516.1"
                     /translation="MKIGFIGLGNMGASLTKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSEIFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            complement(5246..6508)
                     /locus_tag="VQT46_001509"
     CDS             complement(5246..6508)
                     /locus_tag="VQT46_001509"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET2371517.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAVSFLPRLEQ
                     VLVADRKEAGLEPIQFRLDSKASQFVSGQAAQAQDFDTEFLDYILAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(6518..7648)
                     /locus_tag="VQT46_001510"
     CDS             complement(6518..7648)
                     /locus_tag="VQT46_001510"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET2371518.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMVEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGVFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRFQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(7731..9611)
                     /gene="cbpE"
                     /locus_tag="VQT46_001511"
                     /gene_synonym="pce"
     CDS             complement(7731..9611)
                     /gene="cbpE"
                     /locus_tag="VQT46_001511"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET2371519.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDSRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRKDGFVNISTSYKPIPS
                     FQAGWHKSAYGNWWYQAPDSTGEYAVGWNEIEGEWYYFNQTGILLQNQWKKWNNHWFY
                     LTDSGASAKNWKKIDGIWYYFNKENQMEIGWVQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SE"
     gene            complement(9614..10501)
                     /locus_tag="VQT46_001512"
     CDS             complement(9614..10501)
                     /locus_tag="VQT46_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2371520.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLVLAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(10491..10952)
                     /locus_tag="VQT46_001513"
     CDS             complement(10491..10952)
                     /locus_tag="VQT46_001513"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET2371521.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMFLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(10949..11857)
                     /locus_tag="VQT46_001514"
     CDS             complement(10949..11857)
                     /locus_tag="VQT46_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET2371522.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            11850..12047
                     /locus_tag="VQT46_001515"
     CDS             11850..12047
                     /locus_tag="VQT46_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371523.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(12099..12770)
                     /locus_tag="VQT46_001516"
     CDS             complement(12099..12770)
                     /locus_tag="VQT46_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2371524.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(12824..13045)
                     /locus_tag="VQT46_001517"
     CDS             complement(12824..13045)
                     /locus_tag="VQT46_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET2371525.1"
                     /translation="MILMTKNINLTNEELELIQGGADSYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            13317..14126
                     /locus_tag="VQT46_001518"
     CDS             13317..14126
                     /locus_tag="VQT46_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2371526.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHITAIHKAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(14307..15182)
                     /gene="aguB"
                     /locus_tag="VQT46_001519"
     CDS             complement(14307..15182)
                     /gene="aguB"
                     /locus_tag="VQT46_001519"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET2371527.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKLLAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYNLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(15192..16277)
                     /gene="aguA"
                     /locus_tag="VQT46_001520"
     CDS             complement(15192..16277)
                     /gene="aguA"
                     /locus_tag="VQT46_001520"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET2371528.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVV
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(16274..17401)
                     /gene="nspC"
                     /locus_tag="VQT46_001521"
     CDS             complement(16274..17401)
                     /gene="nspC"
                     /locus_tag="VQT46_001521"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET2371529.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDEDMEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFESQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(17401..18660)
                     /locus_tag="VQT46_001522"
     CDS             complement(17401..18660)
                     /locus_tag="VQT46_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET2371530.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMLD"
     gene            complement(18657..19517)
                     /gene="speE"
                     /locus_tag="VQT46_001523"
     CDS             complement(18657..19517)
                     /gene="speE"
                     /locus_tag="VQT46_001523"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET2371531.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEYDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQAFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGAFMLPKYVE
                     DILEEEEGKK"
BASE COUNT         5665 a         4501 c         3471 g         5900 t
ORIGIN      
        1 taattctcaa gctgtgagtt cattatgatt tgtaaatccg atatatcttc agcagctaaa
       61 aacacatttt gaaatgttcc aagtccgttt tcaccaaaac tatattctct cttactatac
      121 ttactcttat tattctctat atagttagag tcaaggttct taacctcttg aagttcattt
      181 tctttacttc tgaggttaaa atcttttact tctgaagtta agttttttga cttctgtaag
      241 tcattttctt ttacctgaaa tatactcata aagtctttaa cataaatgat gttcggctta
      301 ccaagtccaa gccttactct ttcgatcagt cctattcctt tttttacatc aagctcatct
      361 aatgttttta tggcagttgg ctttgagata tttcttcttt tcataatttc ttcgacagta
      421 aaatagataa atactctgcc ttccttgtct atccagttat tcttaaatga cattcctgtc
      481 tgtttaagaa gtatggaata aaggataatt gcttctgctg ataagccccg aaattcttct
      541 ctatcaacta atatctccgg tacttttaag aagttaaatc tttccgcttc tctgttataa
      601 aaatattcaa agtccatgca agatcacctc ccttcttaaa aatttgcaaa gaaaaagacg
      661 atagtttttc ttctatcgcc tttggtaacc atttttatga aattttttaa agttaaaaat
      721 ataatttata atactatctt cttccatttt ctgattttag ttctgaaagt tccaaaaggt
      781 gcaaccgtat ttacatgaat aaacttatac acttcccaag tcgctgtttt agtcgcttca
      841 tcagcccact ttctcatatg cggttcaaat aattcttcct cactcaacga atcaatcatt
      901 gcagagatag aattaatatt ttcatttaat tttgctttca actcttgcag agataaatga
      961 gcgtaggtat ctgtgaacca ctgatataat tcaccaagtt gattccattt aaatttatcc
     1021 gatggtgttt ttacttgaag cccctttctt tcatcttctt cccatttaag aaccaagttg
     1081 gtccaaccaa cctgataagc aaggttttct gctggagttc tgtcaacttc atcagctctc
     1141 ttatctttta aattttctgg aatattatca aattctaaaa tatatttctc aaatgttttc
     1201 tctatctcag cttttagttc ttctttattt tcgtatgttc gcaaaaaatc accttctttc
     1261 tgatttatca atcctttgat ttaaaatgac cttatttttc tatttatacc ttctaagaac
     1321 gctataactg ctgctccaaa catcggtatt ccgtatgggc ttaataaaaa acttaatacc
     1381 aaagcttcta taccaagtga tacatcttta tattatcatc actaattaag ttaaacagaa
     1441 acagacagaa ttattacatc ctgtctccct ttattgtttt tcttcccaat cgtggtaggc
     1501 agcgtagagt tgactcttat tccactggta aatcttagct acttccttaa tagcttgatt
     1561 tttcttcatg ccttgctgga tacgggcttg gatttctaag aacaagtcct cctcgtcttt
     1621 ttcctccaca tcctgactgg caccttcaac aataagaagg cattcgccct tgagtggcgt
     1681 ttcagcgatg ctttccagta attcagaaat tgtacctcgt tggtattctt catagatttt
     1741 ggtcaattcc ctgaccaaaa caaccgagcg gtcaccgtag acttctaaca tattttccaa
     1801 cgtgtctgct acacgatgag gtgattcata aaaaatctgt gtttcaggat aatctttttt
     1861 agagccaaaa aattgcttct gttgacctga ttttctcggt aaaaaaccgt aaaagatatg
     1921 tggctgtggc gctaaaccac tggcaatcaa ggcagaaatt cctgcagagg tacctggaac
     1981 agtcacaact gcaatttctt cctcaatagc tgccttaact aaatcatgac cagggtctga
     2041 aatgctaggc aaaccggcat cagagacctg agcaatactt tgccctgctt tcaagaaacc
     2101 aatcaaatca ggaatttttt ccttggcatt gtgctcatga aaactgatct gcttggtgga
     2161 aatgtcaaaa tgcttgagca aaagccctgt attgcgcgta tcctcagcag caatccagtc
     2221 cacttctttc aaggtctgga tagcacgaaa agtcatatca tctagattgc caatcggcgt
     2281 tgccactaga tacagcttgc catagggaga ctgcccctta aaactttttt gaatttgcat
     2341 gcttactccc tgtataacaa ctcatcacag aacatacatt cttcgtcctg ctctcgacgt
     2401 tgtccataaa aatcattaca tacgtgaaat ccatcacggt aaatacgacg gacactttcg
     2461 cgaacatgct tggccttgac gggagcgtct gcttccacct cacccaagcg ttctcgcaac
     2521 ttactatttt ccaagcgaag agctgtattt tcttctacca agctcttgag atttttcttg
     2581 atggcttcca catcggctaa agttaccaat aattgttggg aaaaatcatc cagcgcgtca
     2641 aataattctt ttttgtccat aaaacagccc tttcctttct ttatcattca tttttgagtt
     2701 tatatttctt tcaagaccag atattccatg gcattttgaa agctgacatt agcttgccac
     2761 atttttctag cttctagtaa atcttgtaga atcactctta ctcttacctg caagaggtcc
     2821 tgcccacaga gaacttcaag aatccgtaaa acctgatcct gtttttcctt atcatctgcc
     2881 aagttggcta atttggcaac ctgtagataa ctttcttttt tcttagctac taaccaagtc
     2941 agcaggcgtt cactttcatc gaccaaggtc caaaaacttg cctgattagc caacttttct
     3001 gcttcagctc gcgattgact aaacttagct aaaagagtcg cttttttctt aacaagtccc
     3061 atttgttcta agagtaagat aagtttttct tcttgctttt taaagtggaa gatctgagtc
     3121 cgacttcgga ttgtcggtaa catcttttcc tcatcgctag tcaagaagaa aatataaact
     3181 tcactctggg gttcttcgat gaccttgagc agagaattgg ctgcgttggg atgcatttta
     3241 tccgcttgct cgatgataaa gacctgttgc tggctttcaa tccctgcttg agaaaactgt
     3301 cccaccaatt cccgaatacg ttctgtcttg atgacctgat tgactggctt aatcaaggtg
     3361 acatctggaa actcttcctg ttcaatcagc ttgcaacttc ggcatttctc acatggtaag
     3421 acgccaactt tatccgtaca aaagaggctc ttagctaaaa attgcgccat ttccaagctt
     3481 ccaaagaaac ctgaaaagag ataggcgtga ttgagctggt cttgttctaa gatacggaca
     3541 aaacggtcaa actgagctgg ttgccaagcc tttagttgat cttgtttcat ttggccaagc
     3601 ccattccgtc aaacaagaca gccttggtag tttccacaac ttgctccaaa gggagactag
     3661 catcaatctt gacaatgcga tttccctctt tatccagaag agaaaggtag ccttgacgaa
     3721 cttttttatg caagtccaac ccttccaaat ccaaacgatt aacctcgcgg tcactattag
     3781 cagcaatacg agccagccct tcttccacct cgatgtcaaa atagagtgtc aaatcgggtt
     3841 tgaggccatc tgtcgcaaac tgattgagcc agtcaatggc ttcaatatct aagccacgac
     3901 caaatccctg ataggcaaca gaactatcga taaaacgatc catgatgacc aacttgccag
     3961 cttcaagggc tggaagaact ttttccacca aatgctgtct gcgactggca atatagagaa
     4021 gtagctctgt tttagcatcc atctgagtat gacttggatc caaaatcact tcccgaatct
     4081 tctccccaat caagactccg ccaggttcac gggtcgtcag cacctttact cctttttcct
     4141 ctaaaattgg tagcagagcc tctaaaacac tggtcttgcc tgctccctct ggtccctcaa
     4201 gagagactaa aaatcctttt gacatgtcta actcatttct tttttactac ttctattcta
     4261 tcaaaaaaat aggggtttgt gacaatcttt ttgtcttctc atttcatact caatgaaaat
     4321 caaagagcaa actaggaagc tagccgcagg ctgtacttga gtacggcaag gtgaagctga
     4381 cgcagtttga atttgatttt cgaagagtat cagccaccat aaaagaggca gataaaacta
     4441 cctcttattt acctagttct tgtgttcgtt tataggcttg atgaactgcc tccatgactg
     4501 tgcctcgaaa agcatgcgct tctaggcttg ctacgccagc aatagtcgaa ccgcctggac
     4561 tacaaacttg atctttcaaa actccaggat gttgctggct ttctaggacc aattgcccag
     4621 ctcctaccac agtttgggct gccattttca aggctgtttc tcgtggtaat cccgtctgaa
     4681 cacctgcatc tgccaaggcc tcaataaaga gatagacaaa ggctggtcca caacctgcaa
     4741 gacctgtcgc tgcattgatt aagctttctc ctaattcaac caagagacca gccttggcta
     4801 aaagctgaca aaagatctca ctgtcctcag ccctgcaatt aggagacaag gcataactaa
     4861 tcactccttg cccgatagaa gcaggggtat taggcatcat acgaataatt cggtgttggc
     4921 ttgggataag acttgctagt ttttctaagg tcaatccagc tgccatcgaa atcaaaagaa
     4981 gactttctct tttttcaagg atggtctggt attgagaaag cagttcagaa aactgagcag
     5041 gcttaacacc tagaaaaatc acatctgctt cttcgaatat ttcttcattg ttagaagtct
     5101 gaccaccgaa gttagcgatg aaagcatcca ccttgacttg actacgattg gcaaggagaa
     5161 tctcatctga cggtctagcc tgcaagacag acttggttaa actagcaccc atattcccca
     5221 aaccgataaa tccaatcttc atctcttact cccttatctg tccatcacca gtgaccacat
     5281 acttgtagct agtcaattcc ttcaagccca taggaccacg cgcgtgcaat ttctgagtag
     5341 aaatccccat ttcacaacca agaccaaatt gtcctccatc tgtgaaacga gttgaggcat
     5401 taacatacac cgctgcagag tccacttgat ctgtaaagta tgctgcagct tcagcatttt
     5461 ccgtcacaat ggcatccgaa tgatgggtac tgtgggattc aatatgcgca accgcttctt
     5521 ctaaactgct cacaacctta acagctagaa tatagtctaa aaactcggta tcaaagtctt
     5581 gtgcttgagc agcttgacct gaaacaaact ggcttgcttt gctatctagg cggaattgaa
     5641 ttggttccaa cccagcttct tttcgatctg caaccaacac ttgctccaag cgaggaagga
     5701 agcttactgc tttgttttca tgaaccagca gaacctccat ggcattacaa acagaaggac
     5761 gactggtttt agcattgttg atgatagaca gcgccttgtc ttcgtctgca tccttatcca
     5821 catagacatg gacaatccca gttcctgtct cgataacagg tacaatcgca ttctcaacca
     5881 ctgcattgat caagccagct cctccacgag gaatgagaag gtctagatag cccttggcct
     5941 tcatcatagc ataactactt tcacggctag tatcctccac cagttgaatc acatttggat
     6001 gaatagtagt cgtctccaag cccttcttca aggctgtgac aatggcatgg gttgtttgat
     6061 aggcatcctt accactacga agaacaaccg catttccact cttaagagtc aaagcagccg
     6121 catcagacgt cacatttgga cggctttcat agataatacc gatgacaccc atagctacac
     6181 gtttttttgt gataaccaaa ccattttcaa gctgacttgt ttctaaaact tcaccgattg
     6241 gatctggtaa ggcaaccact tcacgaattc ctcttgccat cgcttctata cgatctgcat
     6301 ccaaataaag acgatccaac atcacatctg agattttccc cttagccgct gccatatcga
     6361 gggcattagc cgctaaaatt tcctcagtag cagccactaa gtgatcagcc atggctagca
     6421 aggcttggtt tttcacttct tcactagctg tgttaatcga ttttttaaca gcctgtacct
     6481 gttcaaattg ttcttgtcta ctcaccatag tttacctcta aaattctgta aaaagtagtt
     6541 ggatttcagg agtaatggaa atccagtcgt cacggtaaat caagacaccc ttggcttttt
     6601 gaaaacgcaa catatcctcc aaagcagatg ctccaaattg cacgcgtcct tttccaagtg
     6661 attttccact ttccttatca aatactgtca cgatatcacc gtaagaaaag actccttctg
     6721 cttcaacgat accagataag agaagactct ttccatgttg agagagagct tccgcagccc
     6781 ctttatcaac ccaaatagaa ccttgactct gagcatagaa ggcaagccat tgtttctggg
     6841 tacgaagccc cttctcttga gcaacaaagt aagaaccatc ctcggtctcc tctgccgcct
     6901 caaccatgga atctgatttc aaggatgagc agatataaac aggaactcct gattccgtcg
     6961 cgatagttgc agccttgatt ttggttaaca tacccccagt tccgtttgac gaaccagctc
     7021 caccagccat atcaataatc tcacgattga tggtctcgat tctctccaag cgtttggctc
     7081 ttggatctga attaggattt ccagtataga gaccgtccac atctgtcaag aaaactaaaa
     7141 ggtctgcttg gaccatcgcc gctacttgag cacttagagt gtcattgtcc ccaaccttga
     7201 gctcatcaat aacgacacta tcattctcat tgatgatagg aattgcccca cggttgagca
     7261 aaaccgacaa agcctgatgg gcatttttat aacgacgctt atccacaaag tcatcttggg
     7321 tcagcaagat ttgtgcagaa acgatttgac gcaagagaag attggtcgta tattcttcca
     7381 acaaaagtcc ctgccctacc gctgctgaag cctgtttatc agcaatttta gtcggacgct
     7441 ttttaaatcc taaggctcca aaaccagccg caatggcacc tgaagacacc aaaatcaact
     7501 catgaccagc ctcgtgcagc atagccaact gctgggtaat atcctttacc ttactacgtg
     7561 ataaacttcc atcctcattt gtcagagaag aagtgcccac cttaaagaca atccgtttgt
     7621 atttcatagt ctcactccga ttattcatat ttatccatta taacatgaat aacaggaaat
     7681 agaaaagagt tgataggaaa aagaaggccc taaaaccttc ttttctacta ctattctgat
     7741 tccgatttgt ttacactcgt ttcagagctt tgtgaagttg aggatgtcaa atcttgacta
     7801 gttgaagaat ttgtaacact ttcatgttga ctcgtttctt tattttcaag atcctttttc
     7861 actacttctt tggattcttt tatttctgaa tgacttgtag ttttaattgt agcagatttc
     7921 tcgatcggaa catccactaa ccaggcacca cttgaatcca cagtatagcc ttctggtgtc
     7981 ttaccattca caagtaattg accattttct ttcaagaagt accatttatc cttgtcttta
     8041 atccaaccta tagctcgtga accacctgtc ttgtagaaat accaatcatt tgccttttta
     8101 agccagcctt gcttcatagc tcctgattct tctagatagt aatgatgtcc agcaacttct
     8161 atctcacctg tcttcatgat accagtagaa tccatatagt accaggcttc tttatctttt
     8221 acccagcccg ttttcatttc ccctgatgga gcaaagtaat accattgccc cttatattga
     8281 agccaacctg tcttcataga gccatcaaca tccaaataat accactgctc tttatcttga
     8341 acccaaccaa tttccatctg attttctttg ttaaaataat accagattcc atcaattttc
     8401 ttccaatttt tagcagaagc accagagtct gtcaaataga accaatgatt gttccatttt
     8461 ttccattgat tctgtaacaa gatacccgtt tggttaaagt aataccattc accttcgatt
     8521 tcattccaac cgacagcata ctctcctgta gaatcaggcg cttgatacca ccagttccca
     8581 tatgcactct tatgccaacc agcttgaaaa cttggaatcg gcttgtagga tgttgaaata
     8641 ttgacaaaac cgtcttttcg aatatcaaaa actgttgcat catagtcttt gctggctgcg
     8701 ttgattctct caattcctcg ttctttgagc caattaacat actcactatc aacaccattt
     8761 ttccaaggta gactatccga agtttgaaca atcaaactcg gactcaaatt tttaatgaaa
     8821 tccttggtat ttgatttgtt ggtatcatgg tgatgattaa acttcatcaa atcaactttt
     8881 ccaatgagag gaccatactt gtcttctgct ccatgaacat tatctaaatc gcccccaagg
     8941 taaattttct tgccattgac tttcaccacg ctaatcaagg aattggaatt gtcatcccaa
     9001 attttcttta attcacccga tgaatcagtt tcattttcat aattatagag ctgaatatcc
     9061 atgtccccaa actgaaaatg agcatcccct tgtgtgatat tttgaataac tgaaacacct
     9121 ttttctgcag cagtctgtaa aaccttatca tagccataca gattatccca tagacgttca
     9181 gaattagtaa tacgactatc actatatttc ttaagataga ctcggtcaac tggataggta
     9241 gacagtaatt catcaacatt tccaatatga tcactgtggg tatgggtcac caaaataaaa
     9301 tcaagttttt ggacacccaa ttccttcaaa cgacgaaaga cacggtctgt tagaacatgc
     9361 ttataagacg tttcaattcc ttctctccat ggataacgag aatcacttcc atctgggaaa
     9421 tcataatctt ctcctgtatc caccatggca aaatgtccat tgctttcaag aataatcgca
     9481 tcactgccac cttcttgaac attgataaag tggattttat ttcctgaact ttcttgagcc
     9541 tgaacattcc cataccatga caaacctaaa aaagcgccta caagtgctaa actagttaat
     9601 ttctttttca ttcttacttt ctcaatctct ccaaggtttc cttaaaaatc tctgggatat
     9661 ctgctttaaa ttccaaggtc ttacctgttc tcggatgagt aaaacctaaa gtcttggcat
     9721 gaagaaattg tccatgtcct ttcaaagtct tgcgaggacc atagacctca tcaccagcga
     9781 ctggatggcc gatataagcc atgtggacac ggatttgatg agtgcgccct gtctccagtt
     9841 gcaactctac taagctataa tcgccaaagc gttccaagac gtgaaaacgc gtcactgcag
     9901 gcttcccttt agcagttaca gcctgtttct tacggtcttt ttcactccgg ccaatcggcg
     9961 cttcaattac accacgatca ttaggcagat ttccatgaac aatcgcccaa tatttgcgga
    10021 gagacttttt atctttgagt tcttgggcaa gtactagatg cgcatcatcg tttttagcaa
    10081 tcatgagaag acctgacgta tccttatcaa tacggtgaac aatccctgga cgcagaaccc
    10141 cattgatacc cgacaagtcc ttaatatgat acatgagggc atttactagg gttccactgg
    10201 tatgaccagc actcgggtgc acaaccattc cctgaggttt gttaacgaca gccacatcct
    10261 catcttggta gactatttct agcggaagat cctcagccac atactctaat acctctggtt
    10321 ctggcacatg gtaagtgacg acatcaccct cttggactgt gtatttagct ttcttgactt
    10381 gaccattgac caagacctgg cctgatttaa tttgttcatt cgcgagacta cgtgataatt
    10441 ctgacaaatc tgacaaagcc ttatccaaac gcagaccacc agtttcaatt ttaatttcca
    10501 tttatttcct cttttagcat tgcaatcaat aaaataatca ctccaaccgt cagatagcta
    10561 tctgccacat tgaaaattgc aaagttgata aagtcaaggt ggaacatatc cacaacaaag
    10621 ccctgactga ccctgtcaat aaagtttcca agaccacccg cgattattag agtcaaaccc
    10681 aagaacatcc agaatgagtc ctccatgtgt ttatgtaaat accaaatggc acctatcacg
    10741 acaaccagag taatgacagc gaataacagc tgctgatctt gtaagataga aaaggctgca
    10801 cctcgatttt gcaggtaggt caagctaacg aaattgggaa tccaggagcg cacttcaccc
    10861 agtggaatct gctggacgat ataggatttg accaactgat ccagcccaat taaaagcagt
    10921 acaatgactg ccactattgc tctttttttc atgatttcct cttttgatca aaatattctt
    10981 gcatgacttc tacgaagaga gtcccagctt gactaagctc cacttcttca cgtttaacat
    11041 agaccatgcg gttatctagg ttatccttga gacgaataac tgtaatgcca ttaacactgt
    11101 cactatctaa aaatccagaa cctgtcgcat aggcgtccgt ccgctccaaa ataccattca
    11161 aggtggcacg gtctgtcaca ttaaacatct gtgagctagc gctggtatcg acaaagttct
    11221 ctgaataata aaggtactcg tctttctctt gagtgaaacg aaccgttggt aaatccgcta
    11281 aatcctccat gactaattcc tctttctggg ctaaaggatg accctcacag agataaatat
    11341 gggtatggaa aggaatcaat tcgatgacct ccagacctaa cttttcaacc cgttgcataa
    11401 tccccttttt attttgattg ttgaggtaga taatcccaat ctcactatgc ccttgcgcca
    11461 cttcatctaa tatttgaaca gtagttgatt caaaaatacg gaagttctta tagtcaggat
    11521 agcgctctga aaaggccgta atagttggtg gtaagaagtc atagtgctgg ctagcaacgg
    11581 aaaattcatc tttttcttct tcaggattgg catactgatt ttgaaaaata tcaaatcctt
    11641 taaccaattc ttgcgctttt tcataaaatt ccatcccacg acgggtcaag aaagtccctg
    11701 agctggtccg acggaaaatc ttaaagccca actctttttc caaatcacga acagaaatag
    11761 acagactcgg ctgactaaca tacatctttt cagcagcttc acgaaaagta ccactattgg
    11821 caatagccac aacatagcgt aattgttgaa tgttcatctt ctacccccaa cttctttatc
    11881 ttttcattat accatatttt agaagttttc caaaaaggaa aaaagaacat cctattcttc
    11941 ttaactatct tcactatctg cctttctcac gccaatctta ttttcaaaat caattcaaaa
    12001 aaataagtgg ctacacacca cttcagtatc ggaaagaaaa acgttgacta tttgtgaaaa
    12061 aagaaaatgc cggaaaattc cgacattttt ttagtaagct aacttcctga aaataggagt
    12121 aaccaaacat cccagaaggc agtgatattg atgagaatat gaactagtat tggatagtag
    12181 agatttttag tcatgcgata caatagagct aaaatcagac ctccactagc ataaatgaaa
    12241 aaagcaagag gagttaaagc aaaattgata tgaatataac cgaaaataat agcagaaagc
    12301 aaaacatctc cgtaccaagg tgagtttttg aaaaaggttg tcataagcac acctcgataa
    12361 atcaattcct cagcaatagg ggcgatgaag caaacgatga gcaagaaata agggaactcc
    12421 tgtctcccca tcatttctac cgtttcattc aaagaaatct gatttgaaga cagggatatg
    12481 aaatacgaaa agaggaagtc agacatatat gaaatgatgt agcccagtaa aaggtagatg
    12541 aagtacctca gctgccactt gaaatgaaaa attttctttc ctgcaaaaac cagtagatag
    12601 atgaccgcta agaaaagaac tccgctctcc atcaaaagca gaatctgaaa aaattcacga
    12661 cttgctggta gatagggctt tgcgaggtga ttgaaaactc tccaaaacca agttgatttg
    12721 taaaaaatta aggacaatgc tagtaaaatt tgaatagccc gttttttcat attaaattct
    12781 ctgctttctc cacttatttc ttcatattac taataaattt tacttaaaat ctcgcagcac
    12841 ttcctttgca aagatgattg cctcctccaa tatatcctaa atcataggtg cctctgggac
    12901 aaaatccatg aaccggcaga gttaatactg gttctatttc ccaatcgtac ctaccattag
    12961 gatttttacc atatgaatct gctccacctt gtatcagctc taattcttca tttgttagat
    13021 ttatattttt tgtcattaaa atcatgatat atttcctcca ttattcttca gattagttga
    13081 gtaatctgat actcatacct acttacaaaa aaactattat attaagttgg ttttttaatt
    13141 tgtctagttg caacattgac aaacatagta tagcatatct ttgcgaaata tcctcttcaa
    13201 atcatgaatt gtcatcaaaa catcttaaac tataaaatca attagtctca agctttctat
    13261 caatttcttc tccaaaatat gctataataa tagcaaaaga taaagaagga agacctatga
    13321 ttaaactact agccttggat atggacggca ccctcctcaa tgaagccaag gaaatcccac
    13381 aagctcacat tactgctatt cacaaagcca ttgaaaaagg tgtcaaactg gttctctgta
    13441 cgggtcgccc ccttttcggt gtcctcccct actacaaaaa actgggactc gacctccaga
    13501 atgagtatgt gattgttaac aacggttgtt caactcacca gactagcgac tggggcttgg
    13561 ttgactggca agaacttagt ccagctgaca tcgaatacct ctatgacctt gctgaaaaga
    13621 gtgatgttca gttgacactt tttgacgagt cacattattt tgttctcggt ggaaagccca
    13681 atcaagttat tgaaaatgat gctaaactag tattttcaga cctgactgaa atttctcttg
    13741 aggaagcgac tagtggaaag ttccggatgt tccaaggtat gtttttagga acaaaagaac
    13801 aaacagacga ttttgagcag cgttttgctg aagagctttg ccaacgattc agtggagttc
    13861 gttcgcagcc tgtcatttat gaagcaatgc cacttggaac gacaaaggct actgctcttt
    13921 cacgactagc tgagattttg aagattgatt cctcagagat tatggccatg ggcgatgcta
    13981 ataacgatat cgaaatgctc cagtttgcag ggcttgggat tgcaatggga aatgccagcg
    14041 attatgtcaa atctcttgcg gatgccgtta cctcaagcaa cgaagaagac ggcgttgcgc
    14101 gtgctattga gaaatatatt ctataaaaaa gaaaagcaaa tagacagaag ttactgctat
    14161 ttgctttttt gctaatattt taaaatacgg actaatcaat agagaagaat agcgaatcat
    14221 aaaaatcgat ttactagatg ccatagtatc ttatagttgc taataagaag ttagtctagc
    14281 agaatgaatc tctcatttct cccacactaa tctgtaattt gtctatacat ttctggtctt
    14341 ctatctcgaa acaagcccca gtttaggcgt tcacttgctc ccttgtctag gttataagta
    14401 gctaacagaa cagcttcttc ttgtctttca gctcgttcta gaatagctcc tgtttcatcc
    14461 gtcataaagg aggaaccgta gaagtcaaga ctggaactct gtccgccatt ttcctcacta
    14521 ggagtaacct cctctaaacc ataacgattg gctgcgatga ctggaacaat attcgctgct
    14581 gcgtgccctt gcatagtacg ttgccagtga ccacaactat ctgtatccaa aattggctct
    14641 gaaccgatag ctgtaggata aaagagcaat tcagcaccat tcaatgcaag acagcgcgct
    14701 gtttcaggga accattgatc ccaacagata ccgataccaa tcttagcata gcgagtattc
    14761 cagaccttga aaccagtgtt accaggcgtg aaatagaatt tttcttgata ataatggtca
    14821 tctggtatat gggtctttcg ataaacgccc agcacttccc catctgcatc aatgacggca
    14881 atagagttat acaagacatt accatctttt tcatagaaac tgattggtaa aacaacttgt
    14941 agttccttag caagcaactt aaaatgctga atggcagtat tttccgctac agattgggca
    15001 tactggtagt agtcatactg acgttcctga cagaaatagg gatgttcaaa caactcgggc
    15061 aagagaataa tttgggctcc ttgctcagca gcctgacgta ctaaacgctc tgcggtttgg
    15121 atatttgttg ccacatcctt agcgcattgc atctgaatgg ttgcaactct tacatttctc
    15181 atctttttct cctattctgg aatttgttgg gtgatacagt ggatattgcc accacctaag
    15241 agaatatctc tggctggtat tccgacaact ttacggtctg ggaaacactt gctgaggata
    15301 tctaaggcca cttggtcgtt tacatcctca aactgtggaa ccaagacagc cttgttggcg
    15361 atataaaagt ttacgtagga agctgctagt cgttcacctg cgtatcgctc ttcttctcct
    15421 tcttcataga tgtagcctgg caaatcttct tctgtcacaa cttgtcgaac tgcagggata
    15481 ggcaatttat gaatggtgaa gtgacaacct tttgcatctg tttcctgttc taagagttcg
    15541 agatctgctt ttgacatggc atactgggga tcattttcgt catctgtcca agccaaaaca
    15601 acctcagcag gaccaacaaa ggcaacaaca ttatcgacgt gttcattggt ttcatcctga
    15661 taaataccat aaggaagcca aataactttt tcagcaccaa gactttctaa taatgtgttt
    15721 tcaatctcct ctttagtcaa gttaggattg cgaccaggac taagcaagca actttcagtt
    15781 acgagaatag ttccttgacc atcgctatgg attgcgcctc cttccagtac aaaaggttta
    15841 gcatcataga caggcctttc caaggcctca gcaaaacgac tggctacttg gtcatcctct
    15901 tcataatctt gataaagacc atcataggtg cctccccaag cattaaaggc ccaatccacg
    15961 gctaatttct tacctttatc attgacgaga atggttgggc cagtatcacg cgcccaggca
    16021 tcattggtgg gaatgtctaa ataaacaacc ttgtctccaa gataggattg ggcttcagat
    16081 agataggcct gctccaccaa aagatagact ctttcccctt ctgctatggt ctcgatgatc
    16141 tgagtaaatg ctcttttagc agcctttcct tgaaaaggcc atgatcctgg tcgagtcggc
    16201 catatcatga gggtaccatg atggggttcg tactctgctg gcatgtgata gcctaatttt
    16261 tttggactgt ccatcatgat aatctccctt taaagtcttg atagccaaaa gctttgagta
    16321 agctacagtc tccctgttcg tccatgagat agagacttgg caatccaata ccattaaagg
    16381 tattattttt gacaaaagaa taaatggcca tgtcttgaaa ataaagtctg tctccgattt
    16441 ggactggatt ttcaaaacta taatcaccaa tcacatcgcc agtcagacag gtattagaag
    16501 aaagtctgta ggtatgggct ttttcctgtg actcaaagcc atttctcaaa ggtggacgat
    16561 agggcatctc aagtacatca ggcatatggc aggtcgcaga ggcgtctaaa accaagattt
    16621 ccataccgtt ttctacaata tctaatacct cagttgctaa ataacccgca ttaagcgcaa
    16681 tggcttcacc aggctcgata tagatttcaa gattgtaagt ttttcggata cgcttgattt
    16741 ctgaaatcag caaatccaca tcgtaacctt ctcttgtaat atgatgacca ccacccatat
    16801 tgagccattt tacctcatgt aagtagggac caaactgttc ttctactgct ttcaaagttg
    16861 tttgtaaatc atctgctccc tgctcgcaaa gggtatgaaa atgaagtccg tcaaccaaat
    16921 ctagcaaatc gctcggaatc ttgtctatag taactccaaa gcgagaacca ggtgcacaag
    16981 ggtcatagag cgcgtgatct ccttgagttg aacactgagg gttgaggcgc aaaccaacac
    17041 tgacaccagc ctctcgacaa cgagccccat gcttacgcaa ctgtctctct gagttaaaga
    17101 cgatatggtc tgttatccca agcaattcct ccatgtcctc atccttgaaa gctggtgcaa
    17161 aaacatggac ttcaccagga aattcttccc ttgccaattt ggcctcatag agtccactag
    17221 ctgtcgtacc tgatagatac tggctaatca agggataagt tttgtagagg gaatatgcct
    17281 tctgggcaag caagaccttg caaccggcct cttcttgtac atattgtaga atgcggcaat
    17341 tagcttctaa cttggccaag tcaataacat aggctggtgt tggtacttgt tctaacttca
    17401 ttagtccaac atttgtggat tttcaaccac aacccatggc aaaccatact cattcaaagc
    17461 ttccatgaat ggatctggat ctaactcctc aaggttatac actccagctt gtttccaagt
    17521 tccgttcatg actaattttg tcccaatcat ggctggaacg cctgtcgtgt atgaaattgc
    17581 ttgtgacccg acttctgcat agcactcttg atggtcgcaa acattgtaga tgtagatagt
    17641 cttttcaacg ccatctttga cacctgtaaa gatacatcca atattggttt tacctacagt
    17701 acgtggacca aggctagcag gatctggaag caaggctttc aaaaattgaa ttggaacaat
    17761 ttcttggccg ttaaagttaa tggtatccgt acgaaggagt ccaacatttt caagacattt
    17821 catgtgcgtc aagtaagatt gaccaaaagt cataaagaaa cgaatgcgtt tgacacctgg
    17881 aatgttcttg gccaatgatt cgatttcttc atggtgaagg agatacatat ctttttgtcc
    17941 aacttgaggg aaatcatact cacgcttgat agacatagct tcgacttcga cccatttccc
    18001 atcttcccag taagaacctg gcgcagaaac ctcacggaga ttaatttctg gattaaagtt
    18061 ggttgcaaat ggataaccgt ggtcaccgcc attacagtct aaaatgtcga tataatggat
    18121 ttcatcaaaa tagtgtttga gggcataagc tgaaaagaca ctagttacac ctgggtcaaa
    18181 accagaacca agaagagcag tcaagcctgc ttctttgaat ttctcttgat aagcccactg
    18241 ccatgagtag tcaaagtagg ctgtaaaacc aagttcctta caacgttttt cgtagatagc
    18301 acgccactca gggtcttctg tgtcttctgc ttcgtagttg gctgtatcga tatagtgaac
    18361 acctgttgcc aaacaagcat ccataatggt taaatcttga taaggcagag ctacattcaa
    18421 aacagcttct ggtttgtagc tttcaatcag agcaatcact tcttcaacct tgtcagcatc
    18481 aagagcagct gtctcaatct ttgtacttgt tttgccttcc agtttagctt tcaagtcatc
    18541 gcattttgac ttggtacggc tagcaatcat aatctctgta aatgtttcgc tatcttgaca
    18601 aatctttgaa atagcaactt gggcaacgcc cccacaacca ataactagta aacgactcat
    18661 ttttttcctt cctcttcttc taaaatgtcc tcaacatact tgggcaacat aaaggctccc
    18721 acgtgtaagt ttgcagtgta gtattctgtg aaaagctggc gttttttcca gccttccttg
    18781 tcaaaatctt tgacagggtg gtattttttc gatgcaaatc caaacaacca atagccagct
    18841 gggctagttg gaatatgggc ctgataaacc cgactgattg gaaaggcttg attgaccttg
    18901 cggtgcatgc ttcggcaggc cgactcatcc tcgtcaaaga acggactccc atgctggtaa
    18961 atcatgatgc cgtcttcctt cagagctcga taactattgc cgtagaattc cttggtaaag
    19021 agtccttccg tatggccaaa tggatctgtc gcatcgttga tgataatatc atagtcatat
    19081 tcgcagtttc gcaaaaagcg tagcccattt tggtagtaaa tggtaacacg aggatcatct
    19141 aggcctgcag caaagtctgg gaaatactca cgacagacct cgaccaacat ctcatccggt
    19201 tccacgatat cgatttgttc cagttcagga tagagtgtta atacttgggc aacaccgccg
    19261 tcaccacccc caataaccaa tactttcttt ggatttgggt ggacagccat gggaacgtga
    19321 acggtcattt cattgtagac gaaatcatcc gcatctgaga acaagacatg gccatttaaa
    19381 atcagtattt tcccaaaagc tggcgtatcc aagacttcga tatcctgcca ttcacttttt
    19441 ccagcgtaaa gttgcttggc tgttctcaga gacaatttga catctggagt atgaacttca
    19501 gaaaaccata aatccatcta tttctcctta tattata
//
LOCUS       DAVAZV010000045        19049 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVAZV010000045 DAVAZV010000000
VERSION     DAVAZV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19049
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.045"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..283
                     /locus_tag="VQT46_001524"
                     /pseudo
     CDS             1..283
                     /locus_tag="VQT46_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            201..629
                     /locus_tag="VQT46_001525"
     CDS             201..629
                     /locus_tag="VQT46_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET2371532.1"
                     /translation="MSKSTSKRYYQVAIPFTRLFCLVLVSIDYINCLSETADKNWHKS
                     DRIFVTNTGKTVHSSILSKSLQRANERLKKPIPKHLSPHIFIHITISILSENKIPLKT
                     ITDRVGHPDSEVTNSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(1121..1531)
                     /locus_tag="VQT46_001526"
     CDS             complement(1121..1531)
                     /locus_tag="VQT46_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001124848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371533.1"
                     /translation="MPKKKIERISVIHREKILWLKWYFMRDKEKPKYSVLECKMFDAA
                     KNKDMLAYKKYATIKQITDIRVQTSEDDILTAIKEVYVYNHMNVIGACQRILFVSQSP
                     AYNKLNKWFETYSDLYFSIIPLPNMGAYHELVDS"
     gene            complement(1549..1926)
                     /locus_tag="VQT46_001527"
     CDS             complement(1549..1926)
                     /locus_tag="VQT46_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371534.1"
                     /translation="MRKYLKEIKELQELKELLSSRNTPEVIIVEGNDDLGEFFQVDGE
                     LFSDIELLENLKKWREWEVQVIVDDWCNRGLNEYETGILYFPKHEDKMDYIRFNKGLE
                     PLYHALDEPYTTISKSEWLKLLD"
     gene            complement(1868..2296)
                     /locus_tag="VQT46_001528"
     CDS             complement(1868..2296)
                     /locus_tag="VQT46_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HET2371535.1"
                     /translation="MAGNENDGLTSKQIKFIDAMLTEPTIDKACQKAGVSRATGHKYL
                     KVAAVKKTLRLKQDEMMDKTTQMLYLASSNAVSVLNDIMMDAKINPFIRTQAAKTILE
                     QSYKTHEIFGVVRQIEELRLEIEEVSKGDQRVTRTQGIIK"
     gene            complement(2340..2945)
                     /locus_tag="VQT46_001529"
     CDS             complement(2340..2945)
                     /locus_tag="VQT46_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371536.1"
                     /translation="MTFTTIKDDIKAFGKKKHGYMTGYIAKQEELHKQLQNGMIGEKY
                     AKDQLEAYKLEGDTYSRDTYNKIHAEIEKQHDLELEALKEKELSVTADDVAELTLLAS
                     MKMTKDELLGYFEKYKNKPLAIKKLWSIAEQYPEIAINLELFNAEQALESLILFFKRQ
                     LSYCHYSLLINGDKIQAVTTEMVVNSDAPELDRRLDEYLNK"
     gene            complement(3035..3208)
                     /locus_tag="VQT46_001530"
     CDS             complement(3035..3208)
                     /locus_tag="VQT46_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371537.1"
                     /translation="MTENKDNKLLEMMEKGFVLYSKNGIIKYIEIPDHGSIKLKAQDG
                     QLVYKEVTTGEQC"
     gene            complement(3807..4703)
                     /locus_tag="VQT46_001531"
     CDS             complement(3807..4703)
                     /locus_tag="VQT46_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2371538.1"
                     /translation="MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENG
                     EVIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYLQTYNVLMSNKSYVADEFKT
                     KTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINE
                     GYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAK
                     NAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFK
                     AFTIKDKRYSINQLKNKVKQLK"
     gene            complement(4715..5524)
                     /locus_tag="VQT46_001532"
     CDS             complement(4715..5524)
                     /locus_tag="VQT46_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HET2371539.1"
                     /translation="MAKTKVYFWLKIDKKFFDNIFIKRLKTVPGGYTMTVIYIRLMLE
                     SLESDCILYYEGYFNNLKEELALKLDVSEDDIDMTMAYFTKCGLIQIDEDKNAELPQA
                     KAMVMSETNWASYKREQRKKGKLEEVQPSLTFSNSCPTEIEKELEIEVDKEQSPTPST
                     INQDFVNLYKSFEAETGKALSPLQIQELQYMLEDFSPELIHEALKEAVSQGKANFAYI
                     KAILNRWKQDNLLTVELVRNSRAAREAKKQQTNQLEPTSYEDWIPTQEKPF"
     gene            complement(5599..5814)
                     /locus_tag="VQT46_001533"
     CDS             complement(5599..5814)
                     /locus_tag="VQT46_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371540.1"
                     /translation="MNELDISNTQAVFVTVILIGLLLYLNHRDRKKSAQLERENQQTI
                     ETPSEDLNPDYGRYIQLAGVDVWGRIE"
     gene            complement(5816..6016)
                     /locus_tag="VQT46_001534"
     CDS             complement(5816..6016)
                     /locus_tag="VQT46_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371541.1"
                     /translation="MTLDLDNMTQAEFDEAMAEIQLQSPNIFQLISDFVNKKVTSVEI
                     DDLLNMKRAEQVAYIKNYKARA"
     gene            complement(6013..6204)
                     /locus_tag="VQT46_001535"
                     /pseudo
     CDS             complement(6013..6204)
                     /locus_tag="VQT46_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841301.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6193..6483)
                     /locus_tag="VQT46_001536"
                     /pseudo
     CDS             complement(6193..6483)
                     /locus_tag="VQT46_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424675.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
     gene            complement(6653..6805)
                     /locus_tag="VQT46_001537"
     CDS             complement(6653..6805)
                     /locus_tag="VQT46_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371542.1"
                     /translation="MKIVTFKPTKQIDGGFYLPGIDILFVSDKADAKSTEDVILFISR
                     NGLNKS"
     gene            complement(6816..7082)
                     /locus_tag="VQT46_001538"
     CDS             complement(6816..7082)
                     /locus_tag="VQT46_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371543.1"
                     /translation="MEILSKEIQLQGLQLLKQTLETLVELEKQRSSKLDLISRKELMD
                     LLGISATTLDNWEDLALKRYQTPMDGAKKVFYRLSDVYLFLAIK"
     gene            complement(7293..7475)
                     /locus_tag="VQT46_001539"
     CDS             complement(7293..7475)
                     /locus_tag="VQT46_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET2371544.1"
                     /translation="MLITLSLAEKVRIKRARLQLTKKAVSEQLGIKSQTLTKVENGNY
                     DASKRIYESVMTWLVE"
     gene            7537..8040
                     /locus_tag="VQT46_001540"
     CDS             7537..8040
                     /locus_tag="VQT46_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371545.1"
                     /translation="MYKMNRIKQLRKENNLTQRELANETKIPYRTIQRWENGETDIKS
                     DAAQVLADYFGVSIPHLLGYSDLIADTDSDIKAMAYSHLLTFVDEKQIKEFEKEFIRA
                     NDNSDTFGDLGSGEKALEKYYQALCYLVPPFRDILARYSFLSLDEKKSVYNIIVGLSN
                     NLSKENK"
     gene            8114..9277
                     /locus_tag="VQT46_001541"
     CDS             8114..9277
                     /locus_tag="VQT46_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET2371546.1"
                     /translation="MNIIEKIKKNGQRVYYASVYLGVDQLTGKKARTTVTATTKKGVK
                     VKARDAINTFAANGYTVKDKPTITTYNELVKVWWDSYKNTVKPNTRQSMDGLVRVHLL
                     PVFGDYKLSKLTTPILQQQVNKWADKANKGEKGAFANYSLLHNMNKRILKYGVAIQVI
                     QYNPANDVIVPRKQQKEKAAVKYLDNKELKQFLDYLDTLNQSNYENLFDVVLYKTLLA
                     TGCRISEALALEWSDIDLESGVISINKTLNRYQEINSPKSSAGYRDIPIDKATLLLLK
                     QYKNRQQIQSWKLGRSETVVFSVFTEKYAYACNLRKRLNKHFDAAGVTNVSFHGFRHT
                     HTTMMLYAQASPKDVQYRLGHSNLMITENTYWHTNQENAKKAVSNYETAISNL"
     gene            complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQT46_001542"
     CDS             complement(9431..10735)
                     /gene="eno"
                     /locus_tag="VQT46_001542"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET2371547.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            10899..11345
                     /locus_tag="VQT46_001543"
     CDS             10899..11345
                     /locus_tag="VQT46_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET2371548.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(11342..12457)
                     /locus_tag="VQT46_001544"
     CDS             complement(11342..12457)
                     /locus_tag="VQT46_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET2371549.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIDVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGRHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(12466..12795)
                     /locus_tag="VQT46_001545"
     CDS             complement(12466..12795)
                     /locus_tag="VQT46_001545"
                     /inference="COORDINATES: protein motif:HMM:NF019887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HET2371550.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGGNNLLMLKSAELGIAFCSKEMLKKEIPHHVDKRDFLEVL
                     PLIDCLE"
     gene            complement(12749..13111)
                     /locus_tag="VQT46_001546"
     CDS             complement(12749..13111)
                     /locus_tag="VQT46_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET2371551.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHC"
     gene            complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQT46_001547"
     CDS             complement(13170..14603)
                     /gene="glgA"
                     /locus_tag="VQT46_001547"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET2371552.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQT46_001548"
     CDS             complement(14600..15739)
                     /gene="glgD"
                     /locus_tag="VQT46_001548"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET2371553.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTFLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVRTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(15729..16871)
                     /locus_tag="VQT46_001549"
     CDS             complement(15729..16871)
                     /locus_tag="VQT46_001549"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET2371554.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQT46_001550"
     CDS             complement(16861..18789)
                     /gene="glgB"
                     /locus_tag="VQT46_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET2371555.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEYGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAIVTELPDKKWRDGLWLARRKRWGFAERPVNIYEVHAGSWKRNPDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEVIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         5657 a         3987 c         3209 g         6196 t
ORIGIN      
        1 gatgacgagc gacttttttg aagcttggtt tcagaagttt ctcttaccaa cattaaccac
       61 accatcggtt attattatgg ataatgtaag attccataga atggggaagc tagaactctt
      121 gtgtgaatag tttgggcata aacttttacc tcttcctccc tactcacctg agtacaatcc
      181 tattgagaaa acatgggctc atatcaaaaa gcacctcaaa aaggtattac caagttgcaa
      241 taccttttac gaggctcttt tgtcttgttc ttgtttcaat tgactatata aattgtctaa
      301 gcgaaacagc cgataagaat tggcacaaaa gcgaccgtat ttttgttacc aatacaggaa
      361 aaacagttca tagttctatc ttgagcaagt ctctccagcg agcaaacgaa cgccttaaaa
      421 aaccaattcc caaacatctg tcccctcaca tcttcataca catcactatt agcatcttat
      481 cagaaaataa aattccttta aaaacaatca cggacagggt tggtcatccc gactctgaag
      541 tcactaattc catctacacc cacgtcacaa agaacatgaa agatgaagca atcaatgtac
      601 tggataaagt tatgaaaaag attttttaaa aagttttgtc ccttttttgc cctctaaata
      661 caaaaatagc ccttcggata aaatccgagg ggctagaaac gttgttaaat caacggccga
      721 acttttgaat ttcatggttc gggataaaat agttcactga actattttat tttttaaggt
      781 tatcataata tcaaatagtt caattaaata cgctaaatta ctaatatact ttttaccttt
      841 ttcattctaa aatgtaaagt acaaacaatt acaatatact agagggggag taaaaaaggt
      901 aataaaattg acgagttcag caggcaaggg aaatagcact tttcatggtg ttattttttt
      961 aattcagcaa tggagtagcc gcttaattga tagaaacaaa aagcacctag tttcctagat
     1021 gctagcacaa tagcccggat tcgaaccgga atctcctcaa ttaaggtgca atccctatat
     1081 actactcatt gtgctttggt tcattatatc atacaatcaa ctagctatct accaactcat
     1141 gatacgctcc catattcggt aatggaataa tactaaaata caaatctgag taagtttcaa
     1201 accatttatt cagcttgtta taggctggcg actgactaac aaataatatc cgttgacaag
     1261 ctccgataac attcatgtga ttatacacat agacctcttt aatggccgtt aaaatatcgt
     1321 cttcacttgt ctgtacccta atatctgtta tctgcttaat cgtagcgtat tttttataag
     1381 ctagcatatc tttattttta gcagcatcaa acattttaca ctcaagaaca ctatacttag
     1441 gtttttcttt atctctcatg aaataccact tgagccataa aattttttct ctgtgaatta
     1501 ctgaaatacg ttcgattttt ttctttggca tgattacctc ctaaattatt aatctaatag
     1561 ctttaaccac tcactttttg agattgttgt ataaggttca tctagcgcgt gatataaagg
     1621 ttctaaacct ttgttaaatc ggatatagtc cattttatcc tcatgctttg gaaaatataa
     1681 gattcctgtt tcatattcat ttagaccacg gttacaccaa tcatcaacga taacctgcac
     1741 ttcccattca cgccactttt taaggttttc taaaagttca atatcactaa ataactcacc
     1801 atcaacttgg aaaaattctc ccagatcatc gttaccctcg acgatgataa cttcaggcgt
     1861 atttctacta cttaataatt ccttgagttc ttgtaactct ttgatctcct ttagatactt
     1921 cctcaatttc taacctcaat tcttcaattt gtcttactac tccaaaaatt tcatgagttt
     1981 tatatgattg ttcaagtata gtttttgctg cttgagttct tataaaaggg ttaattttgg
     2041 catccatcat aatatcattg agtacagaaa cagcattgga tgaggctaga tatagcatct
     2101 gtgtagtttt atccatcatc tcatcttgtt ttagtctcaa tgtcttttta acagctgcaa
     2161 cttttagata cttatgccct gttgcccttg acacccctgc tttttggcac gctttatcta
     2221 tcgttggctc agtaagcatg gcatctatga attttatttg tttagatgta aggccatcat
     2281 tttcatttcc tgccatctat tacctcctcg ttatcaaaat aaaggggttg ctagcccctc
     2341 tatttgttta aatactcatc caaacgacgg tcaagctcag gggcatctga atttactacc
     2401 atttcagttg ttacagcttg gattttatcg ccgttgataa gcaaactgta atgacaatat
     2461 gaaagttgcc gcttaaagaa taagattaga ctttctagcg cctgctctgc attgaataat
     2521 tccaagttga tagcaatttc tggatattgt tcagcaattg accaaagttt tttaatagca
     2581 agaggtttgt tcttgtattt ttcaaaataa cctagcaatt catcctttgt catcttcata
     2641 ctagctaaca aggtcagctc tgccacgtca tcagctgtta cgctgagttc tttttctttt
     2701 aatgcctcta gctctagatc atgctgtttt tcaatttctg catgaatttt attataggtg
     2761 tccctagaat aagtgtcccc ctctaactta taagcctcta gctggtcttt agcgtatttt
     2821 tcgcctatca taccattttg taactgttta tgtaattcct cttgtttagc aatgtagcca
     2881 gtcatgtacc catgcttttt cttgccaaaa gccttaatat catccttgat tgttgtaaat
     2941 gtcatgttat cctccttacg aaaaaataaa agaggtatga caaaagagcg ttaaactcaa
     3001 ttatcatacc tctggttttt ccagtcagta tttattaaca ttgttctcca gtggtcactt
     3061 ccttataaac taactgccca tcttgagctt ttagcttaat gctaccatga tctggaattt
     3121 caatgtactt tattatacca ttttttgagt ataaaacaaa gcctttctcc atcatttcta
     3181 ataatttatt atccttgttt tcagtcatga atttctcctt tatttcaagt gtcccaacgg
     3241 gtacggttgt aagctgagac attttagggc tatctttgag cgacaaaaat gtcgaaaagt
     3301 cttcagttcc tgtataaccg ttattagttt tgtttgctac tcatttttga gtcacaaatc
     3361 tgttaagcaa aaatgagtaa tagctcgtaa gataagtaaa tctaatactt gtattcctaa
     3421 agcgttgata taactgatat tttcaactat ccaacgctct ttactaccct ttttagtgtg
     3481 ctttagctca tttttgagct tttttgagct tttttgagtt ccattttggg aatgcaaagc
     3541 aggcgcgcac cgtgcatgct tttttcttgc tcatagcctc accctcagaa gtttgccgac
     3601 cgagagcgtg gggcttttta tttttgtata attaaaaaca gctgcacaat ttttgtacag
     3661 ctacgaccga ggcaggggcg acctgccgta ctttacacta gataatatca tctaggtagt
     3721 ccaactgtat tttatcatat taaaggctac attacaattt ctcaccctgt gaagagtgtc
     3781 tatttttgtt taggtttgta agtcgattac ttcaactgct ttaccttatt ttttaactga
     3841 ttaattgagt atcgcttatc tttgattgtg aaagccttaa aagtgttacc ctcaagacct
     3901 tttagaatac ggctataatt ccgctcgttg tatactatct tgagttcatc gctatcaaga
     3961 tttgtattaa atatagtatt ttctcgatta ttcagtacat caaaaagtaa atcctgctcc
     4021 caatcgctct taggtttaat aacagcattt tttgcaccta aatcatcaat aattaagtaa
     4081 tcaacagact tcatgagttc agtagcttca aactctgtaa gtgttgcacc tttaccataa
     4141 ttccacccct ctttaatttg tttgatcatt tcggttaggc ttacaaaaag cacactctta
     4201 ggttctcctt ttgtcttata cccctcattt atacctttgg caatagcaac tgataaaagt
     4261 gtttttccaa tccctgtacc tcctgtgata agcgtatttc ccctcatgcc atcaagatat
     4321 ttttgtacct gaccttttgc aaattctaaa aatcgctttt cttctgatgt tacagcatta
     4381 aaatcatcaa aagttttagt tttaaactca tctgctacat agctcttatt gctcatcaac
     4441 acattataag tttgcagata tagtttagca ttcaaattat cagcaatcgc atcttcttca
     4501 tcttgctttt tctgttcttc ttggcattgt tcacaatagg gtgggataca gcgaacttct
     4561 tttattacct ctccgttctc attccacccc actactacat gtctttctcc tttgatttgt
     4621 gttagctgta tttcatgctt aggacacaat tcgtctagtt taaatgtctc aatatttcct
     4681 aaactagatt gtaatgattt cattttctga cctcctaaaa tggtttttct tgtgttggta
     4741 tccaatcttc atagctggta ggctctagtt gattggtttg ctgtttttta gcctcacgcg
     4801 ctgccctgct atttctaaca agttccaccg tcaataaatt gtcctgtttc caacggttaa
     4861 ggattgcctt gatgtatgca aagtttgctt taccctgact gacagcctct tttaacgcct
     4921 catggataag ctctgggcta aaatcttcta gcatatactg caattcttga atctgtaacg
     4981 gtgacaatgc tttacctgtc tcagcttcaa aagatttata gagatttaca aaatcttgat
     5041 tgatggtaga gggagtgggt gattgttctt tatctacttc tatctctaat tctttctcta
     5101 tctctgttgg acatgagttg gaaaatgtca aagatggttg gacttcttcc aattttcctt
     5161 tttttcgttg ttcacgttta taactcgccc agtttgtttc actcataacc atagcttttg
     5221 cctgtggtag ttctgcgttt ttatcttcgt caatctgtat taaaccgcat tttgtaaagt
     5281 atgccatggt catatctata tcatcttctg atacatctaa ttttagggct aactcttcct
     5341 tgagattgtt aaagtagccc tcatagtata aaatacagtc actttccaag ctctctaaca
     5401 tgagcctaat ataaataact gtcatagtgt acccaccagg taccgtcttt agtctcttga
     5461 taaaaatatt atcaaaaaat ttcttatcaa tttttagcca aaaatagact tttgtttttg
     5521 ccatcgtcct ctcccttgct catttataat tctctacctt gattagtctt aatactcgct
     5581 tgtcattcat tgttagactc attcaattct tccccatacg tctacccctg caagctggat
     5641 atatcgccca taatcagggt ttaaatcctc gctaggtgtt tctatcgtct gttggttttc
     5701 tcgctccagt tgggcgcttt ttttgcggtc tcggtggttt aaataaagca gtaagccaat
     5761 caaaatcacg gtaacaaaaa ccgcctgtgt attgcttata tctagttcat tcatgttatg
     5821 ccctcgcttt gtaattcttg atgtatgcca cttgttcagc tcgcttcata ttcaacaagt
     5881 cgtctatttc cacactggtt acttttttat ttacaaaatc agaaatcagt tgaaaaatgt
     5941 ttggactttg tagctggatt tcagccattg cctcatcaaa ttctgcttgt gtcatgttgt
     6001 ctaaatctag tgtcattgca ttgcctcctc aaacttctct ataagacaac ttttatttgc
     6061 tttctgagtt ccatttttag agttaaaaag aatatatttt aaggttacag tagcctctaa
     6121 atactccttt tcagcatgct ctatatacgc ctgttgctct gcttcgttct caaaaaagtg
     6181 cttagcttag cgtttaaaga atgctttgac taggtttagt ttgaattgcc gtactgcttc
     6241 ggtattcttt agataagtga tcagcaaagt agcctgttgc tcgttcagaa tataggattt
     6301 tttaggttgt cctctagtgt ctaatttatg gattttaaat ccaagtattc ccaactcttc
     6361 aaagtcaacc ttattttctc ttattaagcg tgtgatagtg tggtgttgta cgtcagcaca
     6421 ttcagcgatg atctcgcttg tggtatacgg ctctttcttg ccgtccatgt agactagttc
     6481 cattatggtt ctacctcctg tataaattta gctagcttac tttttaattg tctcctctag
     6541 ccctttttag cctctacaac ggttttggct aacgtgttag aggcttttat aacggcctgt
     6601 atagctgtct ctatttcctc cgtggaatag tagctttgtt ttctaatatc atttaagact
     6661 tgtttaaccc atttcttgaa ataaataaaa ttacatcttc tgtactcttg gcatctgctt
     6721 tatctgagac aaatagaatg tcaatgcctg gtagataaaa cccaccgtct atttgtttag
     6781 ttggtttgaa agtaactatt ttcatttcat aactcctatt ttattgctaa aaataaatac
     6841 acatctgaca gacgatagaa tactttctta gctccatcca tcggggtctg atatcgttta
     6901 agagcaagat cctcccagtt atcaagggtt gtagcactta tacctagcag atccattaat
     6961 tctttacgag aaattaaatc taacttacta gatcgttgtt tttctagctc aactaaagtt
     7021 tcaagagtct gtttaagaag ctgtaaaccc tgtaactgta tttctttaga cagaatttcc
     7081 atttatatcc tccattttcc tttttataaa ttaagttgtc tttttcctct aattttgata
     7141 aaataagaag agattattta gcaaaggggg ttgtcccttt gctaaatacc taacaaaacc
     7201 acgcgccttg cctttgcttg agttttgtta tttttcctta gccgtgtacg ttggtttggt
     7261 cgcctgtaca tggcttttta cttgcgttaa atttattcta ctagccaagt catcacgctc
     7321 tcatagatac gcttagaggc atcatagttt ccattctcaa cttttgttag tgtttgagat
     7381 ttaataccca actgctccga tactgctttt ttggttagct gtaatcttgc acgcttgata
     7441 cgtacttttt cagcaagtga tagtgtaatc aacattggtt tcacctccct tttttctcca
     7501 tttttggcat tttgtgttat aatctcttta gaaaggatgt ataagatgaa tagaattaag
     7561 caattacgaa aagaaaataa tcttactcaa agagaacttg ctaatgagac taaaatccct
     7621 tatagaacca tacaacgttg ggagaatggg gaaactgata taaaatccga tgctgctcag
     7681 gtacttgctg actattttgg agtatcaatt cctcacttac taggttatag cgatttgata
     7741 gcagatacag atagtgatat taaagcaatg gcatactcac atctactaac ttttgtagat
     7801 gaaaaacaaa tcaaagaatt tgaaaaagag ttcattcgtg caaacgataa tagtgatact
     7861 tttggtgatt taggaagtgg tgaaaaggcg ttagaaaaat actatcaagc attatgctat
     7921 ttagttcctc cttttaggga tatattggct aggtatagct ttttgtcact agatgaaaaa
     7981 aaatcagtct ataatattat tgttggttta agtaacaact tatcaaaaga aaataaataa
     8041 ctttaaacat catgtataaa tacctaacaa aaccacgcgc cttgcctgct gatggaaaga
     8101 aaggtacaaa tacatgaata tcatagagaa aattaaaaag aatggccaaa gagtttatta
     8161 tgctagtgtt tatctaggcg ttgaccaact aacgggcaaa aaagcccgta caactgttac
     8221 agcaaccact aaaaagggcg ttaaagtaaa agcgcgtgat gcgatcaata cttttgctgc
     8281 taatggctat acagttaaag ataagccgac aattacaaca tacaatgagc ttgtaaaagt
     8341 ttggtgggat agttacaaga atacagttaa gccaaatact cgccaatcca tggatggatt
     8401 ggttagagtg catttattgc ctgtatttgg cgattacaag ctatctaaac ttactacgcc
     8461 tattcttcaa cagcaagtaa acaaatgggc tgacaaggca aataaaggcg aaaaaggggc
     8521 atttgctaac tactccttgc tccataacat gaataagcgt attttgaaat atggcgtagc
     8581 tatccaggta atacaataca acccagctaa tgatgtcatc gttccacgca aacagcagaa
     8641 agaaaaggct gctgtcaaat acttagacaa caaagaatta aaacagtttc ttgattattt
     8701 agacactctg aatcaatcaa attatgagaa cttatttgat gttgtcctgt ataagacttt
     8761 attggccact ggttgccgta ttagtgaggc tctagctctt gaatggtctg atattgacct
     8821 agaaagcggt gttatcagca tcaataagac actaaaccgc tatcaggaaa taaattcacc
     8881 taaatcaagc gctggttatc gtgatatacc aatagacaaa gccacattac ttttactgaa
     8941 acaatacaaa aaccgtcaac aaattcagtc ttggaaatta ggccgatctg aaacagttgt
     9001 attctctgta tttacggaga aatatgctta tgcttgtaac ttacgcaaac gcctaaataa
     9061 gcattttgat gctgctggag taactaacgt atcatttcat ggtttccgcc atacacatac
     9121 tactatgatg ctctatgctc aggctagccc gaaagatgtt cagtatagat taggccactc
     9181 taatttaatg atcactgaaa atacttactg gcatactaac caagagaatg caaaaaaagc
     9241 cgtctcaaat tatgaaacag ctatcagcaa tttataaaaa ataagggtga cccatttccg
     9301 ggctaccctc ttactatacc aaaaattagt aggggtagta aaaagggtat taaattataa
     9361 aaagcactaa gggaaagcgc cccaaagtgc ttatttcaaa ggctttatag cctataatca
     9421 cataaggaga ttatttttta aggttgtaga atgatttcaa tccacgatat tcagctactt
     9481 caccaagttg gtcttcgata cgaagcaatt ggttgtattt agcgatgcgg tctgtacgtg
     9541 aaagtgaacc agtcttgatt tgtcctgcgt tagttgcaac tgcaatatca gcgattgttg
     9601 aatcttcagt ttcacctgaa cggtgtgata caacagcagt gtaaccagct tctttagcca
     9661 tttcgatagc ttcaaaagtt tcagtaagag taccgatttg gttaactttg ataaggattg
     9721 agttagcagc accttcttgg ataccacgtg caaggtagtc agtgtttgtt acgaagaagt
     9781 cgtcaccaac aagttgtact ttcttaccaa gacgttcagt aagagctttc caaccatccc
     9841 agtcgttttc atccatacca tcttcaatag tgatgattgg gtatttgtta accaattctt
     9901 caaggtagtc gatttgttct gcagatgtac gaacagcagc accttcacct tcaaatttag
     9961 tgtagtcgta aactttacgt tctttatcgt agaattctga tgaagcacag tcaaatccga
    10021 taaatacgtc tttacctggt acatatccag cagcttcaat cgcagcaagg atagtttcaa
    10081 caccatcttc agttccttcg aaacgaggag cgaatccacc ttcgtcacct acggcagttt
    10141 ccaaaccacg tgatttaagg attttcttaa gagcgtggaa gatttcagca ccgtaacgaa
    10201 gggcttcttt aaatgttggc gcaccaactg gcaagatcat gaactcttgg aaagcgattg
    10261 gagcgtcaga gtgagaacca ccgttgatga tgttcatcat tggagttgga agaactttag
    10321 tgttgaatcc accaaggtag ctgtaaagtg ggatttcaag gtagtcagca gcagcacgag
    10381 ctacagcgat agacacaccg aggattgcat tcgcacccaa tttacctttg ttaggagtac
    10441 cgtcaagtgc gatcatagca cggtcaatag cttgttgatc acgtacatcg tagccaatga
    10501 tagcttcagc aatgatgttg tttacgttgt caacagcttt ttgtgtacca agaccaccgt
    10561 aacgagattt gtcaccgtcg cgaagttcaa ctgcttcgtg ttcaccagta gaagctcctg
    10621 atggaaccat accacgtccg aaagcacctg attcagtgta aacttctact tcaagtgttg
    10681 ggttaccgcg tgagtctagg acttcgcgag cgtaaacatc agtaataatt gacatttttt
    10741 actctcctta tgagttaaat tttttacacc tctataatac cttaaaaccc ctcctttttc
    10801 aagaaaaaac gttatctttg tgcaactttt ccttaacttt ataaagtaat cgctttcttt
    10861 tgtctgtttt attctaactt ttatgatata ctgttttcat gacagattta tcaaaacaat
    10921 tacttgaaaa agctcatggt gggttaaaaa taaatccgga tgagcaaaga cgctatcttg
    10981 gtacttttga ggaaagagtt cttggatatg tagatattga cacagcaaat agccctcagt
    11041 tagaaaaagg ctttttattt attttagaaa accttcagga aaaagcagag ccactatttg
    11101 tgaagatttc accaactatc gaatttgata agcaagtttt ctacttaaaa gaagcaaaag
    11161 aaactgatag tcaagccacc atagtatctg aagagcatat tacttctcct tttggcctgg
    11221 ttattcatag caatgcacca gttcaagtag aagaaaaaga ccttcgactt gcttttccaa
    11281 aactttggga agttaaaaag gaagaaccag ccaaaacatc cttatggaag aaatggttta
    11341 gctaaatctt gcacatattt aataagtgcc caatattggc agccgtgcgc tccagataga
    11401 gactggcatt tttcaaacta tcttctaaag gttcactttt ctccaaaata gaaaagacag
    11461 cttggatatt ttcaaatggt aggggaggta aatcttcagc aagactaccg caaatagcaa
    11521 taacaggaac tccaacaggg gttctttttg caacacctat aggcgctttc ccagcaaagc
    11581 tttgactatc aagtcttcct tctccaacaa caaccaagtc agcatctgaa actttcttat
    11641 caaagttgat taagtccaag caggtatcaa ttccagacac gatacttgcc tgagcaaaag
    11701 cacacaaacc accagcaagg cctccacctg ctcctgctcc tttaatttct aatgttgcag
    11761 gtgagaattt ttcataaaaa tcttggatcg cctgatctac gactgcaaac atagtcggat
    11821 gtcgaccttt ttgattgcca aaagtataag tcgcaccttg atgaccacat aagggactta
    11881 cgacatctgc taaaatatga atttgaacac cttcaggaat tttatagcaa ttttctgttg
    11941 aaacagaagc taagtttaat aaggattgac cggaagcagg caagacattt ccatccctat
    12001 cataaaattg ataacctaaa ccagcagcaa tccccagtcc tccatcatta ctggccgtgc
    12061 caccaacatc gatataaata tctttaatcc ctttagaaat gagatggaga atcaactctc
    12121 caataccaca agtttggatt tgaagtggat ttcgtttctc tagcggaatt tttccaagac
    12181 caaccaagtc agctacttca aatagtgcca gttccccttt ttgaaaatag cgcatggctt
    12241 ctttttgtcc aaaagggtct gtcacttgga tccatttttc ttttaggtca agagaatgtc
    12301 ggatagcatc tacagtacct tctcccccat caccaacagg gcagaggaga cattctacat
    12361 ctgctatcga ttgttggaag cctcttttta ttgcttcagc tacctgttga gctgtcaagc
    12421 tttccttaaa cgaatccggt gcaattacaa tcttcatatt ttccctcatt ctaaacagtc
    12481 aatcaaagga agaacttcta aaaaatccct cttgtcaaca tgatgtggta tttctttttt
    12541 gagcatttct ttggaacaaa aggcgattcc taactccgcc gacttcaaca ttaatagatt
    12601 attgccccca tcaccgattg ccaccgttct ttctttagaa agttttagtt tctttctcca
    12661 tttttccaga gtttcttttt tgacctgggg acttataatt tgtccaacta attttcctgt
    12721 taaaagacct tctttgactt caagctggtt agcagtgaaa taggcaatac caagggattt
    12781 tgctaatctc tccaactatt ggtgtaaatc caccagacac cagaccaact aggataccat
    12841 tcttttggag aatagagatg aactctggga catttagcga tagatgaatt gagttgaaga
    12901 cgttatcaaa gaccaaaata ggaagacctt ccaacaagga cactcttttt cttaaactgc
    12961 tttcaaagac caactctcct cgcattgctc gacttgtaat ctgcgaaatt tctgcctcat
    13021 gacctgcctc tctccctaaa agatcaatca cttcttctag gattaaggtt ccatctacat
    13081 ccaaaacaca caagcctttt acttgagaca tcagttctcc tctctaaaca gcctaaaaat
    13141 cgtatgaagt catcatacga ttttatctat taattaacta aactatggta caagtcaagg
    13201 tatgacttgc aggctgtatc ccatgagaag tcactctcca tagcttgttt ttgtaggttt
    13261 ctccaaatgt ctggatggtt tctatacaag tccaatgctg tttggaaagt ccaatttaac
    13321 caataaggag atagattgtc aaagctaaag ccagtaccgc ttccttcgat tggattgaaa
    13381 gcgcgaactg tatctcgcaa gcctccaact tcatggacca atggcaaggt tccataacgc
    13441 atagccatca tttgagacaa gccacacggt tcaaaacgac ttggcatgag gaagaggtca
    13501 caagcagcgt agatttcctg agcaagtttg acatcaaaag tgatatttgt tgatagcttg
    13561 tctgggtaaa tctgagcaaa ccatgagaaa gctccttcaa aggctggatc gccagttccc
    13621 aaaagaacaa tctgaacatc ttcttgcaag atatggtgaa gactttcgac caccacatca
    13681 aaaccttttt gacgtgtcaa acgagaaaca attcccacca gtggaacgtc tgctctaaca
    13741 ggcaagccaa ctctttcttg caattttgcc ttatttttgg ctttcccaga caaatcttcc
    13801 tgattgaaat gatagtctaa aagagcatcc gtctgaggat tataaagatc agcatcaatc
    13861 ccattcacga taccagatac tttaccagac tccattttaa gaatctgatc caaattacat
    13921 ccaaactgac tagtcataat ttcatgagca tagctaggtg aaacggttga aacacggttc
    13981 gcatagagaa tacctgcctt catccagttc agacagttgt tccatcgaag ggtgccatca
    14041 gcgtaacgtt caaagccaac tccaaacaaa tcacccaaca ttccttctga aaattgtcct
    14101 tggaattcta aattatgaat ggttaaaact gtttcaatgt cctcataggc ttgaatccaa
    14161 cggtattttt ccttcaacaa gaaaggaatc atagctgtat ggtagtcatg aacatggaga
    14221 agatcaggaa taaagtcaat cctttccata gcctcaatgg cagccagttg gaaaaaggca
    14281 aagcgttctc cgtcatcaaa atcaccgtaa acatgaccac ggaagaaata atattgattg
    14341 tcaataaagt agaaggttac accatttaat actgttttct taattccaca atactgtctg
    14401 cgccaaccaa cgctcacctc aaaatgaagc acatcttcaa tctgatttcc aaatttagcc
    14461 tctaccatat catagtaggg taaaatcact gcaacttcgt gcccagcttt taccagtgat
    14521 tttggaagag cgccaatgac gtctcccaaa ccacctgttt ttgaaaaggg tgcaccctct
    14581 gctgctacaa ataaaatttt catgaatgaa tatcctctgt tactttagca cctttcttaa
    14641 ccacaactgg atgttctgca gttcctcgaa tcacaacacc aggctcaact tcaacccctt
    14701 tgtccaagat agcatattcg acctgagccc cttctccaat aacaacacga gggaagagca
    14761 ggctatcttt aaccaagcta tccttatgga catggatatt acgtgataga acagaattag
    14821 ctacttgacc ttcaataata ctaccagagg caaactgaga agttcttacc ttagatgtat
    14881 tagcatagta agttggctct tcgtttttga cctttgtata aatcttttgg tttggtgaga
    14941 aaagagaata gaatttttgt gattcaagca tatcgatatt cgcttgataa taagatttaa
    15001 cagagtgaat attggctaga tagcccgtgt actcgtaggc gaaagctccc tcttttacag
    15061 ccaaatcccg taaaacatag cgcaatttct ctggatgttc ttttttagct tcttcttcca
    15121 agtgttcaat caaccaaggt gtatcaacga caaagatatc tgtagacata ttgaacgttt
    15181 cagctgttga cttgctatca aagagtttat gagaaagaac atggtctgtt tcatctacat
    15241 ccaagattgc atttacttct gaaatatctt tcttagctag ttttttataa actacagtga
    15301 taggctcttt tgttgtacta tgtaggtgga aaacttggtt caaatcaatg ttaataagaa
    15361 catcgcagtt gagggcaacc gtttggtttg agccagaacg tttcaaataa gtaagaagct
    15421 gttggtagta ttcttttcca actgtactac tttctacacg ggtattgtaa attcctagat
    15481 agtaatggct aagaaaggtt gataagcccc actcgcgtcc tgaacgaata tggtcaaata
    15541 ctgagctgat attatcctgc tggaaaatac caaagacact acgaacacct gcattagcaa
    15601 ggcttgaaag tgggaagtca atcaaacgat atttcccacc aaatggcaaa cttgctactg
    15661 gacggtggtc cgtcaatgtc gacatattgt gaaaaccaac tgtatttcct aaaatggcag
    15721 aatatttatc aatcttcatc tgttgctacc cccactactt cattatatcc tacaacttgt
    15781 acttcatctg ttccatcaat ttcgacaccg tcagaaataa tcgcaccttc accaataatg
    15841 gcacgtttaa tcttagctcc ttgaccaatg atagctccac tcatgataac tgaatcaagg
    15901 acttccgctc cttcgcgaac ttgcgcgcct gttgaaagga tagaatgttt aacagttcca
    15961 tcaacgaaac atccgtctac aactaatgag tcttccacat gagcatttgc cccgaggaag
    16021 tttggtggtg aaatcaagtt tcttgagtaa atcttccatt gacggttacg actatccaag
    16081 gcattttctg gagaaatata ctccatgttc gcttcccaaa gtgactcaat agtaccaaca
    16141 tctttccaat aaccactaaa ttcgtaagca taaacacttt cacctgactc aaggtaattt
    16201 ggaatgacat ttttaccaaa gtctgacatg ccaaccttgc tcttttcagc agcgactaac
    16261 atattacgaa ggcgttgcca atcaaaaatg tagattccca tagaagcttt tgtagattta
    16321 ggttgagctg gtttttcttc aaattcaaca atacgattgt tagcatctgt gttcatgata
    16381 ccaaaacggc ttgcttcttt aagagggacg tctaaaactg ctactgtcaa gctggcatta
    16441 ttatccttat gagactggag catatcatca tagtccattt tgtagatgtg atccccagac
    16501 aaaatcaaga catactcagg attgacactg tcgatatagt cgatattttg gtaaatagcg
    16561 tgactagtcc cctcaaacca acgatttcct tcacttgcag aataaggttg aagaatagag
    16621 acacctgaat taataccgtc tagtccccag cttgaaccat tcccaatatg gttgttgaga
    16681 gcaagtggtt gatactgtgt aacgacccca acattatgaa tccctgagtt ggcacagttt
    16741 gatagggcaa agtcaatgat acggtagcgc ccaccaaatt gcacagctgg ttttgcgatg
    16801 ctttgagtga gtttaccgag acgagttcct tgcccaccag caagaatcaa agctaacatt
    16861 tcatttttca ttttctactc ctttttggtt tttatttgtg acggttttag tagatttcaa
    16921 gcgacgtttg attttccata cacttgctcc catagccggt agggtaaagg ttaaggtctg
    16981 ctcataatct ttccatagtc cttcttgcgt ttgaacagtt tgattatgtt ctttccaaac
    17041 gcctccccac tcttccaact cagtattcca tacttcttcg taaattcctg caacgggtag
    17101 tccgattgta aaatctttcc gctcaacagg taccatgtta aagatacaga ctaacatttc
    17161 tcccttttta cccttacgaa taaaggaaag aacactctgg tctcgattat ccgcatcaat
    17221 gacttcaata ccatcatagc tggtatcgat ttcccacaga cagcgatgat ctttgtaaaa
    17281 ctggtttagc tgagaagtga aatacttcat cttagcattc attgggtctt ctaggttaga
    17341 ccattccaac tgttcttcag atttccattc taggaattga ccgtattcgc tacccatgaa
    17401 gagcaatttc ttaccagggt gacaaatttg gtacgtatag agattgcgca agcctgcgaa
    17461 ttgattgtaa cgatctcccc acatcttatg catcatactc ttcttgccat gaaccacttc
    17521 atcgtgcgag aatggcaaga gataattctc cttgaaaaca tacataaagc tgaaagtcac
    17581 caggttaaag tcatatttac gataaatcgg atcttcttcg tagaaacgga ggatatcatt
    17641 catccagccc atgttccatt tgtagtcaaa tcctagacca ccaatctctt tcattcccgt
    17701 aatcttggtt gcagacgaac tttcttctgc aatcatcatc acatctggat attctaactt
    17761 aataacttca ttcaagcgtt gaaggaaata ataaccttca tagttgagat ttccgccatc
    17821 tttattaggt gtccatggag catcatcata gtccaaatag agcatgttgc taacagcatc
    17881 cacacgaata ccatccaaat gatagatatc aatccaatgc ttaatgcaag aaattaagaa
    17941 ggactggact tcattttttc caaggtcaaa attaagggca ccccaaccat ggttatgagc
    18001 cttattatgg tcttggtatt caaaagtcgg tgtcccatca taataggcta aggcatcatc
    18061 attgatggta aagtgacctg gtacccagtc cacaataacc ccaatattat gggtatgaca
    18121 ctcctcgaca aaatcttgaa actcctctgg tctaccatag gcatgctcta aagcgaagta
    18181 acccataagc tggtaccccc aactcaaacc tagtgggtgg gacatcaagg gcataaactc
    18241 aatatgagta tagttcatct caactaggta aggaatgagt tcatctttca attgggcaaa
    18301 actataagga ctgccatcag gatttctctt ccaagagcca gcatgaacct cgtaaatatt
    18361 gacaggacgt tcagcaaagc cccaacgttt tcttcgtgcc agccaaagtc catccctcca
    18421 tttcttatca ggaagctctg ttacgattgc ccctgttcct ggacgagcct catacctgac
    18481 agcaaaaggg tcaatcttca tcagttgatg accattttga cgtgtgacat gatatttgta
    18541 aatatgccct tcttgagcca tattggtaaa gacttcccag accccaaagt catttcttac
    18601 cattggaatc tgattttcaa tccaattggt aaaatcacca accaagtgaa cagcctgagc
    18661 attaggtgcc caaacacgga aggtatagcc atactctcca tttagttctt ccctatgtgc
    18721 tcctagataa tgttggagat aaaaattttc acccgtcata aaggttttta atgcttctct
    18781 attatccata tactcccttt ctcctgtaag cgttttctat gtttttatta tactaccttt
    18841 ttagagaaga ttcaagtaaa ttactatact tctttaatta ttttgaaaat ctacaacaag
    18901 ttcacttact cgttcaattg taaatcaata ttttttcaaa aaattgcgaa aacacctttc
    18961 tttttctact atagtgaaat gaaataaaac atgcgcaaat cgattaagga atttaatcta
    19021 atttctaaca atgtcttaga aatcaaagt
//
LOCUS       DAVAZV010000046        17803 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVAZV010000046 DAVAZV010000000
VERSION     DAVAZV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17803
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.046"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..222)
                     /locus_tag="VQT46_001551"
     CDS             complement(<1..222)
                     /locus_tag="VQT46_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAM domain-containing protein"
                     /protein_id="HET2371556.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCT"
     gene            260..1036
                     /gene="recX"
                     /locus_tag="VQT46_001552"
     CDS             260..1036
                     /gene="recX"
                     /locus_tag="VQT46_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET2371557.1"
                     /translation="MKITKLEKKKRLYLMELDNGDKCYITEDTIVRFMLSRDKVISEE
                     ELKEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINANQLSGDKGPYVLTQKLAQKGISKSTIEEILNDFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYFDAKIAFDELDSQVDEETTQELIFKELDK
                     QYTKYARKYEGYKLKQRLTQVLARKGYDFSDIASALREYL"
     gene            1125..1658
                     /locus_tag="VQT46_001553"
     CDS             1125..1658
                     /locus_tag="VQT46_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET2371558.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(2098..2854)
                     /locus_tag="VQT46_001554"
                     /pseudo
     CDS             complement(2098..2854)
                     /locus_tag="VQT46_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(2992..4614)
                     /gene="groL"
                     /locus_tag="VQT46_001555"
     CDS             complement(2992..4614)
                     /gene="groL"
                     /locus_tag="VQT46_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET2371559.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            complement(4630..4914)
                     /gene="groES"
                     /locus_tag="VQT46_001556"
     CDS             complement(4630..4914)
                     /gene="groES"
                     /locus_tag="VQT46_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET2371560.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            complement(5184..5579)
                     /locus_tag="VQT46_001557"
     CDS             complement(5184..5579)
                     /locus_tag="VQT46_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET2371561.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            complement(5657..6418)
                     /locus_tag="VQT46_001558"
     CDS             complement(5657..6418)
                     /locus_tag="VQT46_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET2371562.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            complement(6451..7077)
                     /locus_tag="VQT46_001559"
     CDS             complement(6451..7077)
                     /locus_tag="VQT46_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET2371563.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            complement(7093..7410)
                     /locus_tag="VQT46_001560"
     CDS             complement(7093..7410)
                     /locus_tag="VQT46_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET2371564.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            complement(7407..7706)
                     /locus_tag="VQT46_001561"
     CDS             complement(7407..7706)
                     /locus_tag="VQT46_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET2371565.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            complement(7991..8182)
                     /locus_tag="VQT46_001562"
     CDS             complement(7991..8182)
                     /locus_tag="VQT46_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET2371566.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            complement(8343..9017)
                     /locus_tag="VQT46_001563"
     CDS             complement(8343..9017)
                     /locus_tag="VQT46_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371567.1"
                     /translation="MKKKAFGIVLLVLAAWILLQGNFGIPSLDGKIWPLLGIVFFAYK
                     SIESILRRHLTSAVFTGLLALIIANYAYDLLPVTNHSLIWASILVVLGVGYLTHSSKF
                     WNEKKWWYNGKKTVVTDKEVAFGSGTFYKQDQDLVDDQVEVAFGDAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLTIRGDVAFGKL
                     EIVYVK"
     gene            complement(9023..9469)
                     /locus_tag="VQT46_001564"
     CDS             complement(9023..9469)
                     /locus_tag="VQT46_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2371568.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            complement(9571..10086)
                     /locus_tag="VQT46_001565"
     CDS             complement(9571..10086)
                     /locus_tag="VQT46_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET2371569.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVCVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLFLHVS"
     gene            complement(10083..10445)
                     /locus_tag="VQT46_001566"
     CDS             complement(10083..10445)
                     /locus_tag="VQT46_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 family protein"
                     /protein_id="HET2371570.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICSVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            complement(10511..12370)
                     /locus_tag="VQT46_001567"
                     /pseudo
     CDS             complement(10511..12370)
                     /locus_tag="VQT46_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001850459.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
     gene            complement(12387..12857)
                     /locus_tag="VQT46_001568"
     CDS             complement(12387..12857)
                     /locus_tag="VQT46_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET2371571.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQMQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            complement(12981..13697)
                     /locus_tag="VQT46_001569"
     CDS             complement(12981..13697)
                     /locus_tag="VQT46_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2371572.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            complement(14578..15987)
                     /gene="ply"
                     /locus_tag="VQT46_001570"
     CDS             complement(14578..15987)
                     /gene="ply"
                     /locus_tag="VQT46_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET2371573.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQHEKITAHSMEQ
                     LKVKFGSDFEKIGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLRQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFESLIKGVAPQTEW
                     KQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTSFL
                     RDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTP
                     KAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRT
                     ISIWGTTLYPQVEDKVEND"
     gene            complement(15998..16330)
                     /locus_tag="VQT46_001571"
     CDS             complement(15998..16330)
                     /locus_tag="VQT46_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371574.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDYLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            complement(16401..17009)
                     /locus_tag="VQT46_001572"
     CDS             complement(16401..17009)
                     /locus_tag="VQT46_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371575.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            complement(17022..17480)
                     /locus_tag="VQT46_001573"
     CDS             complement(17022..17480)
                     /locus_tag="VQT46_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET2371576.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            17605..17715
                     /locus_tag="VQT46_001574"
                     /pseudo
     CDS             17605..17715
                     /locus_tag="VQT46_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            17714..17803
                     /locus_tag="VQT46_001575"
                     /pseudo
     CDS             17714..17803
                     /locus_tag="VQT46_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558195.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
BASE COUNT         5260 a         3960 c         3256 g         5327 t
ORIGIN      
        1 agtacaagat ggcacaattc gaaatttaga cttcttgttg accttcagta attttgcttc
       61 aacaaagttg cgtctaatag aagtaatctg acaatagata tcttcgcctt tgagagctcc
      121 tggtacaaag actaatgttt tttggtaaaa gccgattccc tcaccgttaa ttcccatgcg
      181 cttgattttt aatggtattt tttgtttcac tttcagattc atacccctat cttatcacat
      241 tttgagttat aatagagcta tgaaaatcac aaaacttgaa aagaaaaaaa gactctatct
      301 gatggagctt gataatggcg acaaatgcta tatcaccgaa gatacaattg ttcgttttat
      361 gttatcgaga gataaggtga taagcgaaga ggaattgaaa gagattcaag actttgctca
      421 attttcttat ggtaagaatc tggccctcta ccacttatcc tttaaagcac gcactgaaaa
      481 agaagtcaga gaatatctga aaaaatacga tattgataaa aacatcgttt ctcaagttat
      541 tgctaatctt aaagaagata agtggattaa tgatggtcag tacgcttatg ctatcatcaa
      601 tgccaatcaa ctttcaggag acaagggacc ttatgtactg actcagaaat tagcacaaaa
      661 aggaatttca aaatctacta tagaagaaat cttgaatgat tttgattttt cggaagttgc
      721 tcaacgtgta gccaataaac tattgaaaaa atatgaggga aaacttccag ctcgtgccct
      781 gcaagataag attatccaga acttgactaa caagggcttc tcttattttg atgctaaaat
      841 tgcctttgac gaattggata gtcaagttga tgaagaaacg actcaggaac tcatcttcaa
      901 ggaacttgat aagcaatata ctaagtatgc ccgaaagtat gaaggataca aactgaagca
      961 gcgtttaact caagttttag cacgaaaggg ctacgatttt tcggatatag caagcgctct
     1021 tagagaatat ctttaatatt tccaagtgaa attcacagat tttaggtaat tttatggtac
     1081 aatagtaaat gataaactta taaattgtag aaagttggtt agttatgaag cttccaaaag
     1141 aaggcgactt tattacaatt caaagttata agcatgatgg gagtctccac cgaacttggc
     1201 gggacaccat ggtactaaaa acaacagaaa acgccattat tggtgtcaac gatcatacac
     1261 ttgttaccga aagtgatggt cgtcgttggg tcactcgaga accggctatt gtttactttc
     1321 acaagaaata ttggtttaat atcattgcca tgattcgtga taatggaact tcttactatt
     1381 gcaatatggc tagcccctac tatctggatg aagaagcact gaagtatatt gattacgatt
     1441 tggatgttaa aatttttaca gatggggaaa aacgtctctt ggacgttgaa gagtacgagc
     1501 gtcacaaacg caaaatgaat tattctgatg acttggacta tattttaaaa gaacatgtca
     1561 aaattcttgt tgattggatt aacaatggac gtggtccttt ctcagaagcc tatgtaaaca
     1621 tttggtacaa gcgctatgta gaactaaaga atcggtaaag ttgtcaaagg tcaggaacaa
     1681 aatcctgacc ttgttttttt ggtagtataa aataaattgt gtaaacacaa aaaggaataa
     1741 atccattata gcagagttac aacacatttc tataaagaaa tttattccta cgactcagtt
     1801 tggcatgctt aacttcctaa ctcaaaaaca aagcatcgat taatttatcc gttcttcttt
     1861 tgaaacagat ttgaactgat aattgctcgt tttaatttaa gaagctcttt tgagcaaaac
     1921 ttcatttttt taagagtcca acaatttctg tctatcgctt ttctactagc aaaaaacctc
     1981 ccttgaggca agttttcatt tatatatcta atttcgtaac agtatagtaa aatgaaataa
     2041 ggacagtcaa atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca
     2101 atctactata aatttgatat gagaatagtc tttctcaaca tccttatcca acaagcatgc
     2161 tgtggcgtcc ttcttaactt gaaccaggtc aatattctgg gcttgggctg ccatagacgc
     2221 agccacaata acattgacga tagatatcat actcctcaca catctctact gaacgtttgt
     2281 agccttgatt tttcttgaaa tcgttgggaa gatagtgggt cgtgtaaatt ttttgcacat
     2341 cgattccgat gctattgatg gtttgagaat tcttatgagg actgatggtc aaggctgaac
     2401 caaagtagtc aaagcccaag tccatagcca cttgcgctgt tttatccagt cggtagtcaa
     2461 aacaaacctt gcaacggtcg ccaccttcgg gctcctcctc tagtccccta actagttttc
     2521 ggtattaatt gggttcgtag ggagcttcta ggtactgaac cgtatttcct gtccgatcat
     2581 taaaatcact aacaaatttc ttgatgacat agacccgctt atggtattct actttgggat
     2641 ggatattaga attggcaaaa tagatggtca catctgcata cttggtcaaa tattctagtg
     2701 tataggtact acaaggggca cagcaaacat gcacgagaat ggttggccgc tgctcatttt
     2761 tctcccatgc ttgtaccatt ttctgcatga cacggtcata attaatcttc tgattggggg
     2821 gcatcttgca cagaatttct tctacatcga tcatgttctt ctcctttttc tagtcttatt
     2881 ttatcatata agttagaaga gctcaaatca atttagaagt gaatattata aaaagaaggg
     2941 ttagtcattc cctccttttg tgttttttat aagttgtttt ctatagaaag cttacatcat
     3001 cccgcccatc atacttggat ccattgctgg agctggggct actggttctg gtttattggc
     3061 tacgactgct tctgttgtca aaatcaagct ggctacagat gctgcatttt gtagggctga
     3121 acgactcact ttaactggat caatgatacc ttgatcaatc atgttaaccc actcgccagt
     3181 tgctgcgttg aatcctatac caagctcagc atttttcaaa cgatcgataa cgatagatcc
     3241 ttcaaatcct gcattgtgag caatttgacg aacgggttct tccaaagcac ggagaacaat
     3301 attacgtcct gttgcttcat ctcctgtcaa ttccaaggta gcaacagctg gaatcacatt
     3361 ggcaagagct gttccaccac ctgcaacaat accttcttca acagctgcac gagtagcgtt
     3421 gagggcatct tcaatgcgga gtttcatttc tttcaactca gtttcagttg cggctccgac
     3481 cttaataacc gctacaccac ctgacaattt ggccaagcgt tcttgcaatt tttcacggtc
     3541 aaattcagaa gttgtagttt cgatttgaga cttgataacc gcaacacggt gagaaatcgc
     3601 ttcaggattt cctgcacctt ctacaataac cgtgctatct ttgtccacgg tcactctcgc
     3661 tgcttgacca agagcttcaa ttgtcgcatc tttcaactca agaccaaggt cttctgtgat
     3721 aactgttccg cctgttaaga tggcgatatc ttcaagcatg gctttgcgac ggtcaccaaa
     3781 accaggtgcc ttgactgcta ctacgttgaa ggttccacga atcttgttca aaacaagagt
     3841 tggaagagcc tcgccatcca catcatccgc aataatcaag agtggacgat tgctttggag
     3901 aatgctttcc aaaagtggca agatttcttg gatattggaa attttcttgt ctgtaatcaa
     3961 aatgtacgga ttttcaaggt cagccaccat tttttcgcta tcagtcacca tgtactgtga
     4021 aaggtaacca cggtcaaact gcattccttc tacgacttca agctctgttt ccataccacg
     4081 tgactcttcg atggtgatga caccgtcttt gccaactttt tccattgctt cagagatgta
     4141 ctcaccaact ttttcagaac gagaagatac ggctgcaact tgagcgatag cttctttatt
     4201 ggcaacaggg atggcgttgt ttttcaaagc ttcaactgct gcggcaactg ctgtttcaat
     4261 cccacgacga ataccgattg gatttgcacc tgctgtgacg tttttgattc cttcacggac
     4321 gattgcttgg gtcaaaacag ttgcagttgt agttccatca cctgcgatat cattggtttt
     4381 tgaagccact tctgatacca atttggcacc catattttca aaatggtctt ctaattcaat
     4441 ttctttggca atagtcacac cgtcattggt aatcaatggt gagccaaatg atttttcaag
     4501 aacgacattg cgaccttttg gtcccaaggt tactttaaca gtgtctgcaa ggatatcgac
     4561 accacggacc atagctgaac gggcatctga tgaaaattta atttcttttg acatacttac
     4621 tttctccttc tattcttcaa tgattgccaa gatgttagct tcgcctacga tgatgtactt
     4681 ttcatcgcca tctttgacat caagacctgc gtgggcttca actaagacac ggtctccagt
     4741 tttaacactt ggagcaacca agtcaccgtt caaggtacga acaccttgtc cagtagccac
     4801 aacttgggct gttttggttt tttcttgggc tgaacctgcg agaacaaagc ccccaacggt
     4861 ttgttctttt tcttctattt ttaagaccac acggtcccct aatggtttca acatctgatt
     4921 tcctccataa tgagatagat attattagcg ctctttatac ctgagtgcta attcatagtt
     4981 ctattgtatc acttagtcag aaataatcaa gaaaaaagtc tgactttctc aagataaaaa
     5041 gcctgagacc aactcagact ttttaatgtt tatactcaat gaaaatcaaa gagcaaacta
     5101 ggaagctagc cgcaagctgc tcaaagcatt gctttgatgt tgtggataaa gctaacgtgg
     5161 tttgaagaga ttttcgaaga gtattaaaat ggcaattctt cctcttccaa gactaaatct
     5221 gccaaatctt ggcctgcatt attttcacgc atggcacgtt gagcacgact ttccaagagt
     5281 tggaatcctg ttacaagtac ttcggtcacg tagttcattt ggccattttt ctcaaagcga
     5341 cgggtacgca attctccatc aacggaaatg agactacctt tggttgcgta gcttgccaaa
     5401 gtttctgcta gtctgcccca taggaccata ttgacaaaat cagcttcacg ttcaccgttt
     5461 tggtctttgt aacgacggtt cacagcgata gttgctcgcg ctaccgactt gtcattgttg
     5521 gttttgtgca attctggtgt agacgttaaa cgcccaatca tgataacttt attatacata
     5581 ttttcttcct cctacttatc tattcgtagg aaatcaaaaa aagttacaga aatttgtaac
     5641 ttttcgagga aatttcttat tttttatgaa tcatgaaacc tgtcgcctgt tgattggcca
     5701 taatggtcat atctgtaatc tgaacacggc gaggctgact ggtcacatag actactgtgt
     5761 ctgcaatatc ctgagcttgc aaggcttcta ttccttggta aacggacgca gctcgctctt
     5821 tatcaccatg aaaacgaaca gttgagaaat ctgtttcgac aatcccaggc tgaatggttg
     5881 tcaccttgat atccgttgcg atggtatcaa ttcgcagtcc atccgaaaag gtcttaaccg
     5941 cagccttggt agctgagtaa acagcggcac cagcataggc gtagattcct gcggttgacc
     6001 ccatattgat aatatgacct tgattgactt ttatcattgc tggcaagaaa cagcgagtaa
     6061 ccgccatcag acctttaaca ttggtatcca acatggtcaa catatccaac tcctcatagt
     6121 cttgataggg agccaagtca agagccagtc cggcgttgtt gaccaagata tcaatcctcc
     6181 ctatcgtttc tagaatatca gagcaaacag tcttcaccat gaccatatcc gtcacatcta
     6241 gtggaaaagt ccagacggtt tgatttggaa agcttactgc aaactccgac ttgaggattt
     6301 ctaatctgtc tatccgtcgt cctgttagaa cgacatcctc accctgctcc agataagcac
     6361 gcgcaatcgc ttcaccgatt cctgaggttg ctcccgtaat cactacattt tttgccatct
     6421 tatttccttc tatcagatgc tgacaagttc ctaggcagtc cagtgtttcg ctgggtcgaa
     6481 cggtgttccg acaacttggt cttctgataa ttcaagcacc ccacgttttt gcggagcatt
     6541 tggcaaatgc aattcacgag gactacacat catcccaaaa ctcttttcac cacgaagttc
     6601 gcctgggaaa atgaaattcc cttttggcat catggcacca ggaagagcca caatggtttt
     6661 caacccaaca cgcgcattag gtgctcctgc aacgatttgc actatcttgt cacttgcgac
     6721 tgcaacttgg cagatgttga ggtggtcact gtctggatga gctaccatct cgacaatttc
     6781 accaacaaca aacttaggtt ccttatcatt aacaatttct tctgtaaaac cttccgcctg
     6841 taattcttgg ttcaaacgag cgacttgctc atctgataaa aagacttgac cgcgctctgc
     6901 aatttcaaac aagctcgaaa cctcaaaaat gttccaagcc actgtttccc cattttcttt
     6961 gaggaaaaca cgggctacct tgcctttgcg ttccacattc agtttggcat ctccgctatt
     7021 tttcacgatg accataagga catcactgac atgttctttg ttatacgtaa aaatcattgt
     7081 ttcctttttc tcctatttca atcctgctaa aaaatcgtta atttgctcct tacttttacg
     7141 gtcgcgattg acaaaacgac cgatttcctt gtccttttct agaacaacaa ggctaggaat
     7201 tccgtaaaca tcccagagtt tggccaaatc catatactga tctcggtcca ttcgaataaa
     7261 ggtgaactct ggattggtct cttcaatctc tggtaaggca ggataaatat aacgacaatc
     7321 gccacaccag tctgccacaa aaaggaagac cttcttgccc gctttttcca ctaaagatgc
     7381 taattcttct aaacttgctg gctgtatcat aagacttcct cctcatagac taggtcttca
     7441 ttttcataga caaaggtata atgacggcca tcctcaaaaa tgacgccacc aaccaagctc
     7501 tccagactgc tttcgtaaac ttgaacataa agggtcgcaa tttcccccat gtcggaaaaa
     7561 tggtctcgca caatctctgt caactcttcc tgagtcttca tgagcttacg gtcatctgca
     7621 acttttttcg tagcaagagc aaggcttccg atacctagca gagccaagcc tgccatccac
     7681 atttttttag ctttcatacc attcatttta acacaaaaaa ggcttcagga caaatgagga
     7741 agcagcagaa aagcaagtaa aaagcctctt cctttaagga aaaagacttc ttatactaag
     7801 agcaaactag gaagctagcc gcaggctgct caaaacacgg ttttgaggtt gtagataagg
     7861 cgacgttgac gtggtttgaa gagattttca aagagtatta ttcttattgc caggcaccta
     7921 agttgccaac gtagtaacta tcaggtgtgt aggtattgcg aagcatctta cctgatgaag
     7981 ccagataata ctacttgcca ttgtctttga cccaatcatt cgcaatcatg gaaccagaag
     8041 aacttacata ataccattct cccttgtcat aaacccaagt actgactttc atggttcctg
     8101 agcaattaaa ggcaaaaaaa ctgtccaata tcattcgttt tttaaaagca tttgacacta
     8161 catcatctac gctgtagtac atagatacat caaacgtaaa agccaaaata tcgaaaaata
     8221 tacaactttt aaaggcagca tttcattttt taaagtctaa caaccataga actgaaatca
     8281 gagcaaggca tcaatttcct actcttagta cgtctatttt gatggttgaa gtgaagattt
     8341 ttttatttaa cgtagacaat ttccaacttc ccaaaagcca catctccacg gatagtcaag
     8401 gttttgctgg ttggggctac aggagcgtca gccttagctg caccaaagga ggtttctact
     8461 ttcaaatcta cacgccagtg ttgtggaaca tagacggttg cattcccgaa ggccacttca
     8521 atatttaaag ttgcaaaatc acctagcatc tctgcattat catagtagat tttagcatcc
     8581 ccaaaagcga cttccacttg gtcatctacg agatcttgat cttgcttata gaaggtcccg
     8641 ctaccaaaag cgacttcctt atccgtgacg actgtttttt tcccattgta ccaccatttt
     8701 ttttcattcc agaacttact tgaatgcgtc agataaccaa caccaagtac caccaagatg
     8761 ctagcccaaa taagagaatg attggtaact ggtaacaagt cataagcgta atttgcaatg
     8821 atgagcgcca gtaaacctgt aaaaactgcc gaagtgagat gacgtctaag gatggactca
     8881 atggacttat aagcaaaaaa aacaatacct agtaaaggcc atattttacc atccaaagaa
     8941 ggaattccaa aattcccttg cagcaagatc caagctgcta aaaccaacaa aacaatacca
     9001 aatgctttct ttttcatgtt ttttacctca tgtttcttag attttctttt aggagggatt
     9061 ggtaatgccg tgagacatga acctccttgt gcgtctgata aaaggaaatg gtgcccgttc
     9121 ctgaaaagga cttgtccact gagtaaatct gacggatgtt tgcgatcgtt gacttggaaa
     9181 ctcgattaaa atagcgaggc aagatagact ccaactcata gagcttgagg cgaacctcat
     9241 aagcttcctt ctggttatga gcgtagatct tgctcccttc tgtttcaaag aagagaattt
     9301 ctgacaggtc tagataatat tcacctgtcc ccttgtaaaa agtcaacctc ggagcctttg
     9361 actcttgcaa gagccgttgc aagtctgcaa tttcatctgt caaagtgggg gtcttgatga
     9421 caatttcagt ctcctctaaa ttgccgtcaa tctcaattcg taacttcatc acatctcctt
     9481 tctgactcta ctatatcaaa gctaagttag gaatacaagg gcaaaaaagc aagtggtcaa
     9541 tttgaagcag taagtggttg taggactagc ttaacttaca tgtaagaata ggaagaaaag
     9601 gaatccccac accaaaccac aagcatagcc aaccaagaca tccttgggat aatgaacacc
     9661 ccctaaaacc ctcaccaacc ccagcaaagc tgaaaagatc aagcatacta agccaatagg
     9721 tagactagca tgcagacagg ccatggagat gatagttgcc gaaaagacat ggcgactggg
     9781 catcgaccgt cccgaactat ccttatcaag aaggggacag atatcccaag tttcataagg
     9841 tctcgggtga ttgattttct tacgaaacag ggacaaggcc acaaaacctg atgcaggaat
     9901 aagcacacaa accccaactt gctgaccaag tcctagttgc aggtaagtgg tgactagcaa
     9961 gatcagatag accaggggca tggcgactgt catcaaacga ttgaaactgc gtaataggaa
    10021 taaaagaatt ggacgactag ttagtctgga gctgatattt cgataccatt cttgataatt
    10081 tttcatttat gcttctcata cttttctaga acttgttgag atgttttccc cttggcaagc
    10141 caatccacta gcttgtccaa gcgacgtatt tcctgcatca gaggatcatc aatttcctca
    10201 atacggacac tgcaaatctt ccctgtaatt gcaattcgtt cagggacata atatggtgct
    10261 tgtctaaaaa aatctccgta agtaacatcc ctatccagac aagcaagaac atcactcact
    10321 tcataccctg tcaaccaact ggtcacttgg tgaactgact ctgcctttcc accctttcgc
    10381 tcaacttttg caatcaaggc taagtagaca gcagcaaatt tcatattgta taatttctga
    10441 ctcatacttc tctctttcta tgtgtactag tataaataag aaaaagaagg ccgtcaagcc
    10501 ttcttttgat ttattcttct gcttcatctt ctgtaaattg actattgtac aagtcagcgt
    10561 agaagccacc ttgcgccatc agttcctcat agttgccttg ctcgatgata tttccatctt
    10621 tcatgaccaa gatcaagtct gcatttcgga tggttgacaa gcggtgggca atgacaaagg
    10681 atgtgcgtcc ttccatcaaa cggtccatgg ctttttggat caattcctct gtccgtgtgt
    10741 caacagaaga agtcgcctca tccaaaatca aaagcggtgc atccttaaga agggcacgag
    10801 caatagtcaa tagttgtttt tgtcctacag acaaggtcac ggtgtcatcc aagatggtat
    10861 catagccatc tggcaaggtc ataataaagt ggtgaattcc cacagcctta ctagcttcca
    10921 tcattcgttc atcactaatc cctatttgat tatagatgag attgtctcga atagttcctt
    10981 caaagagcca ggtatcctgc aagaccattg aaaaggcatc atgcacttct gaacgcgtca
    11041 tagccttggt atccacacca tcaatgtgaa tacttccctt atcaatctca tagaatttca
    11101 tcaaaagatt gacaatggtt gtcttaccag tcccagtcgg cccaacaatg gcaacctttt
    11161 gaccagcatg aactgtcgca gagaagtcat agtcttgaac attgacaccg tccaccagaa
    11221 tttctcctgc tgacacgtcg tagaaacgtg gaatcagatt gaccagagtt gatttaccag
    11281 aacctgttga cccaataaag gccactgttt gaccagtttc tgctttaaag ctaacatgtt
    11341 caataactgc ctccgaattt gccgcatagc ggaaggtcac atccttaaac tcgacctgac
    11401 ctttgaagtt ttcatcagtc agctgcactt gaacagggtt ttggatagaa gaatgcaaat
    11461 ctaaaacttg attaatccgc ttagcagaga ccatagtttg gggaagaacg atgaagagtg
    11521 ctcccatgag aaggaagtcc atgacaacct acatggcata agacatgaaa acaatcatgt
    11581 cactaaagag aggcagacgc gctatcggag cagcgtcgtt aatcacatag gccccaatcc
    11641 agtaaatcgc cacactcaaa ccacttgaaa tccccatcat gataggattc aaaatagcca
    11701 taagacggtt gacaaacaaa tttaaacggg tcaattcatc atttactgct gcaaattttt
    11761 cattttgata atcctctgca ttgtaggcac gaacgacacg aatacctgtt aaactctcac
    11821 gagtgatact gttcagttta tctgtcagcc cctgaatcaa ggactgtttt ggaaaggcta
    11881 gcgtcatcaa aacggtcgtc atcaggacgt tgacaatcac tgccacaagt acggcccaga
    11941 gccagtattc tgaatgacct aaaatcttcc caatagccca gatagccata attggaccac
    12001 acgttaccac ttgcaagtcc atagtaatca acatttgaac ttgagtaatg tcattggtag
    12061 tacgcatcaa gaggctagga attgaaaatt tcttaatctc tgtctgcgag taatccaaaa
    12121 ctcggttaaa aatatcactt ctcagcctac tagtataaga agccgccact cgggatgcaa
    12181 aaaatccaac tgcaactacg gacaagaagg caagaaaggg cattcccatc atcatgcttg
    12241 ccggctgcca caactcatct aaattagttc cttgactacc tagcaaatcc gtaattttcg
    12301 agatataggt cggcacttcc aactctagat agaccgaaaa gcaagtaaag agaatggcta
    12361 gtaaaatcat cccccattct tttctactaa ttcttttgac taatttcttt attctctcct
    12421 cctattccct tgatatttgc ctgtagttga ccgagaactt tctcaaaaat cagtaattca
    12481 tcttcatcaa tgtcttccat caactgcttg tctatgcgtt caaaaaaagc cttaacctgt
    12541 tgcatctgag aacgtgcttt gtccgtcaga cgaacaaact tagcccgctt atcaacagga
    12601 ctcgcctcca attccaccaa accattttgc actatacgct taaccagatt actagcaaca
    12661 gacttggtaa tattgagttc ctgctcgata tctttaatca agaccaagtc ttggtttttc
    12721 tcgcgattat ccaaaaaatg cacaacctga ccttgcggcc cacccataaa ttcaatgccg
    12781 caacgtttgg cttccttttg caccatcagg tgaatttgat gaccaaaacg cttaaagact
    12841 aacatcggtt tatccataat ctcccccttc taaataaaaa tagttctctg gagaataatt
    12901 aaatttctat gagaactatt ttcttgatta aaaaaatccc aagtgatttt ctcacttagg
    12961 atcatgttct ataggttaaa ttaaaaccca tctacgttcg tataaatctt ttggacgtct
    13021 tcgtcgtctt caagaacgct gtaaagtttt tcaaaggttt caaggtcttc gcctgacaat
    13081 tccacttctg actgaggaat catttccaat tcagtcactt ggaattcttc aataccagac
    13141 tcacggaggg caacgatagc cttgtgaagg tcagttggcg ctgtgtaaac tgtgattgta
    13201 ccttcttgtg cttctacgtc atccacatcc acatccgctt cgagcaattg ctcaaagact
    13261 gcgtccgcat cttcacctcc aaatacaata acacctttgt tgtcaaagag gtaagaaaca
    13321 gaacctgaag cgcccatgtt tccgccgttt ttaccaaagg ctgcacggac attggctgct
    13381 gtacggttga cgttagaagt caaagtatcc acaattagca tagagccatt tggcccaaaa
    13441 ccttcgtaac gtccttctgt aaaggtttcg tctgtgtttc ctttggcttt atcaatcgct
    13501 ttatcgataa tgtgttttgg cacttgggct tgtttagcac ggtcgataac gaatttcaaa
    13561 gctgagtttg attctggatc tggatcacct tttttagctg ctacatagat ttctacacca
    13621 aattttgcat atactttaga gttggctcca tctttagccg ttttcttggc tacgatattg
    13681 gcccatttac gtcccattag gaatctcctt ttttcacatt ttaatctttc ttattataac
    13741 acaagttttt ttgattttca ctagaggaaa tggattttat tagcaaatca agctaggata
    13801 gcactttacc tgctaagatg gtcttgcctt tctatcttta tcaacagaca ctcatccaca
    13861 ttcaaaaaac aaactagacc attatctgca aatagaaagt ttcagccaag tttgacaaag
    13921 tcagctcaaa ttactgtttg aagtttgtag atataagcga caaaaacaat catactgcac
    13981 cttttgttga cagtctactc cagacatatc atagttcaag taaatacttt gaaatccaac
    14041 agttcttata ggcgctattg tattctaaga aatcaataga agagtttcta agcaaacctc
    14101 taatactcaa taaaaatcaa agagcaaact agaaagctag ccgcaggttg ctcaaaacac
    14161 tgttttgagg ttgcggatag ggctgacatg gtttgaagag attttcgaag agtataattt
    14221 acgtgttcct aagatggaga agttagacta gtacactggc acttctaaac cattgctagc
    14281 aattgatttg ttcatattta atttcatttt ttccataaat gggtattaga tataaacagc
    14341 aaaatatttc cgatacgtgt cattcttgaa tttccaatca tctaaaacaa gtaaaggata
    14401 atcaatcccc tgtatatcaa ggaattggct acccttttta cttttttaca catcctgttt
    14461 gatagactca ttttaacatc acgagcatac tccaatggaa atcgctaggc aagagataaa
    14521 ctttcagata ttcgcagaga gctcatcgcc tctttttgtc gcaaacattc ttctctccta
    14581 atcattttct accttatcct ctacctgagg atagagagtt gttccccaaa tagaaatcgt
    14641 ccgcttacgc actagtggca aatcggtttt ttcataaacc gtacgccacc attcccaggc
    14701 aagcccggta cactctctaa ttttgacaga gagattgcga acattccctt ttaaaggaat
    14761 actagtggta aagtgagccg tcaaatcctg cccatttctg tcccaagcct taggagtcaa
    14821 gacttccttg ccttgatgat cataggataa ttcatcccaa gtaatataat attgggcaac
    14881 ataggcacca ctatgatcca gcagtaaatc tccgtttctg taagctgtaa ccttagtctc
    14941 aacatagtct gtactgtttt gaaaggtcgc aactacattg tcacgtaaaa aagaagttgt
    15001 ataggaaatc ggcaagcctg gatgatcggc tgtaaagcga ctgccttctt gaatcaagtc
    15061 ctctaccata tccaccttgc ctgttacaac tcgggcaccc gaacttgggt cgccccctaa
    15121 aataaccgcc ttcacttctg tattgtccaa aatctgcttc cactctgtct gaggagctac
    15181 tccttttatc aaagattcaa aagcagcctc tacttcatca ctcttactcg tggtttccaa
    15241 cttgagatag acttggcgcc cataagcaac actcgaaata tagaccaaag gacgctctgc
    15301 agaaattcct ctctgcctta aatcctctac cgttacagta tcttgaaaca catctcctgg
    15361 atttttaaca gcatctacgc tgactgtata ataaatctgc ttaaaattaa caatctgaat
    15421 ctgcttttcg cctgaatgga cagagttaaa atcaatatca agagaattcc ctatcttttc
    15481 aaagtcagaa ccaaacttga ccttgagttg ttccatgctg tgagccgtga ttttttcatg
    15541 ctgcattcta gctgggacat tattgacctg accataatct tgatgccact tagccaacaa
    15601 atcgtttacc gctccgcgaa cacttgaatt gctggggtct tccacttgga gaaagctatc
    15661 gctacttgcc aaaccaggca aatcaatact ataagtcatc ggagcacgat cgaccgcaag
    15721 aagagtggga ttattctcta acaaggtctc atccactacg agaagtgctc caggatagag
    15781 gcgactgtcg ttggtagctg ttacagaaat atcacttgta tttgtcgaca agctccgctt
    15841 ctttctttcg ataacaacaa actcatcggg tagctgatta ccctctttga tgaaacgatt
    15901 ttcaatactt tctccctgat gggtcaagag tttcttttta tcgtaattca tagctagtat
    15961 aaagtcattt actgctttat ttgccatctt ctacctccta ataagttcct ggattgagtt
    16021 gcataaactc agacttgttc agcgaaatca gccgtggttg gactaagtaa tccaaaattt
    16081 cctcgtacaa ttcttctgag acattgcgtc gccgtctggc taaataagaa gtcggaatga
    16141 ccgtattatc caacataaat accttatcta agtcaatcaa ggttggtctt gtaaaaggat
    16201 tacgagctag atccggctct tctatcataa agttcttgac caaacgtctg gtcaagagag
    16261 ctggtttgaa ggtctgattt ttaaccaact ctttgttttt agtcatgctg ttgtcaatac
    16321 agatatacat atgattcttc acagccaaat cgctactaat agtcggaaaa ggcaaataaa
    16381 gagctacaac atctcctctc ttaatcaagc aagagcaccc ccttttctcc taatgtaaca
    16441 tagacaggat tgaccaagtc ttctgattga ctcagaattt ccaaagtttg agtttggcgc
    16501 gctgtcaatt tagtagcatc ttgtctcttc aatacaaaat gcttgtcgcc aataaccttg
    16561 acaatataat ccttctccaa agctgactgg taaatccaca tcagatgttg tctgtcctga
    16621 gaactcaaga gagaaggatt ttcaagcctc ccgatagtct gataaaaatc aaaaacagga
    16681 gctaactcct gccaatctga ttggctagtt gtcaaggcta gaaaaagggc tttgcgagct
    16741 gatacttctt ggttagcctt gagagttact ttcccctcca agttttttag aaatcgggaa
    16801 actccagaaa gcaaattttt ctctaactgc gagaaataaa aacctttcgt tcccagacat
    16861 aagtctttca tgtcgctttc tctagcaaat aagagctcaa acatttgata gtaaaagaaa
    16921 aatatctggc actgggtcgc gctcatcttt tccttatcgg cttctttttt taaccagagc
    16981 aagggcgaca ggtagctgga ttgagacatt tcctctacct cctactcttt tttaactgga
    17041 gcatctgcac tagctgccac ttcttttgac tggatacttt cccactggtt aatctcctct
    17101 gagataagac cttcgcatgt cttgacaaat agggcaaaag ccttggtctt tcctgcatat
    17161 ttctccgttt ggcattgata gaggaatttt tctttctcca ggagttgcgc agttttttgg
    17221 taagaaatcc aattttcctt tgcattatac aaattgataa tcccctcaca cagcaagccg
    17281 agactggata aggcaaccga aatcaaacgg tagcgatcac ctggcatagg aatagcacaa
    17341 aagacagcta tgaggaaacc tgccacgatt tctgttattt ttaatacctt atagcgccta
    17401 cgatgttgaa cgcttttctt taaaaaatga gctatctgta cgtctaatcg ctctgtcagg
    17461 tacatttctt ctggcgtcat attcgtaact cctttcattt actttgataa ccatagtata
    17521 acatatttga atatcaaagt atagtaaaaa ctggactata acttattaga ctccctgcga
    17581 aacaaaatat ggtatagtag ttctatgaat tatgaagcaa gtaaacaatt aactgataca
    17641 cgatttaagc gtcttgttgg tgttcagcgt accacttttg aagagatgtt agctgtatta
    17701 aaaacagctt atcaaaaaag tcggacaagc tggtaaaatc ttggctgaca gtggttatca
    17761 agggctcatg aagatatatc ctcaagcaca aactccacgt aaa
//
LOCUS       DAVAZV010000047        17572 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVAZV010000047 DAVAZV010000000
VERSION     DAVAZV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17572
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.047"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(179..1114)
                     /locus_tag="VQT46_001576"
     CDS             complement(179..1114)
                     /locus_tag="VQT46_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET2371577.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1111..1971)
                     /locus_tag="VQT46_001577"
     CDS             complement(1111..1971)
                     /locus_tag="VQT46_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET2371578.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFYYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2079..4241
                     /locus_tag="VQT46_001578"
     CDS             2079..4241
                     /locus_tag="VQT46_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET2371579.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATITSYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIATLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIILSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPDYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLSYHEIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMIRYFPQVWASDNTDAIARLPIQYGSSYFYPTISMGA
                     HVSAVPNHQMGRMTPLETRGHVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTASNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4333..5592
                     /locus_tag="VQT46_001579"
     CDS             4333..5592
                     /locus_tag="VQT46_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2371580.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRSE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5606..6472
                     /locus_tag="VQT46_001580"
     CDS             5606..6472
                     /locus_tag="VQT46_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2371581.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6486..7319
                     /locus_tag="VQT46_001581"
     CDS             6486..7319
                     /locus_tag="VQT46_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2371582.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKSTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIIAGISNGAV
                     K"
     gene            7320..7400
                     /locus_tag="VQT46_001582"
                     /pseudo
     CDS             7320..7400
                     /locus_tag="VQT46_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            7538..8980
                     /gene="gtfA"
                     /locus_tag="VQT46_001583"
     CDS             7538..8980
                     /gene="gtfA"
                     /locus_tag="VQT46_001583"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET2371583.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTEILPEIHEHYSIQFKIADHDYYVYDFTLPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAREVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVSF"
     gene            9118..10311
                     /locus_tag="VQT46_001584"
     CDS             9118..10311
                     /locus_tag="VQT46_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET2371584.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            10998..12977
                     /locus_tag="VQT46_001585"
     CDS             10998..12977
                     /locus_tag="VQT46_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2371585.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAAKETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13044..14540
                     /locus_tag="VQT46_001586"
     CDS             13044..14540
                     /locus_tag="VQT46_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371586.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14540..15466
                     /locus_tag="VQT46_001587"
     CDS             14540..15466
                     /locus_tag="VQT46_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371587.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSIRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15475..16542
                     /locus_tag="VQT46_001588"
     CDS             15475..16542
                     /locus_tag="VQT46_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371588.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16553..17479
                     /locus_tag="VQT46_001589"
     CDS             16553..17479
                     /locus_tag="VQT46_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371589.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
BASE COUNT         5175 a         3141 c         3674 g         5582 t
ORIGIN      
        1 aggctccata atatccatag ggaatttacc cactacaaat attatagagc ccgttttaat
       61 gagagtttgt aactctcttt tttgttttta gagacaataa aacttcagat ccgtaaaact
      121 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      181 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      241 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      301 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
      361 atagctcttc tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc
      421 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
      481 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
      541 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
      601 cattgaccca ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag
      661 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
      721 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
      781 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
      841 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
      901 tttcttctag aatctctgga agaataaggt caccattcat cagtttatat cctctatttt
      961 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg
     1021 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1081 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctca ctagttggta
     1141 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1201 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1261 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1321 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     1381 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     1441 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     1501 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     1561 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     1621 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgagaaa gagcaaaata
     1681 atcaggggat ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     1741 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     1801 aacaatttta cccttgtaat aaaattttcc ttgtccttta gtaatgtaat gtagaacgta
     1861 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     1921 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     1981 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2041 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2101 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2161 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2221 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2281 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca actatacagg
     2341 ttcagcatag tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     2401 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     2461 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     2521 ataatgatgc gactattact agctacagta aattagataa taatagtaat caggaagttg
     2581 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagcaa
     2641 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     2701 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     2761 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     2821 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     2881 gcattaatcc agaaaacttt tcttggaagt tagcccctga ggaatacttt gaaacaccgg
     2941 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3001 ttgtactgaa gcacattatt ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3061 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3121 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3181 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3241 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3301 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca ccctgactgg gctattcagg
     3361 ttcctgacta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     3421 aggtagtaga atacttgaaa agtgtcttag atcaactcct atcttatcat gagattgatt
     3481 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     3541 agacacagat gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga
     3601 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     3661 ttggtatgat acgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     3721 gtttaccaat tcaatacggt tcatcctatt tctatccaac catttctatg ggggctcatg
     3781 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccatg
     3841 tagcaatgat gggaaatttg ggctatgagc ttgatttgac aaatttatca gatgaagaga
     3901 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     3961 gacagcagta tagactaatt aatcctgata ctgcatccaa tgaagcagct gtacaattta
     4021 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4081 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4141 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag
     4201 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4261 ttagatttat tctatctaac ttttgaagtg cagtttgata agggtgtata aatttataaa
     4321 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     4381 ttgtttgggc tcggtgcttg ctccaactat ggtaaatctg cggatgacac agtgaccatc
     4441 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     4501 gagaaggaaa accctaagat aaaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     4561 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     4621 atcgaactgc aagaatgggc aaaagcaggt gtctttgaag atttgagtaa caaagactac
     4681 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     4741 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     4801 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     4861 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     4921 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     4981 tctcaaccaa atgctattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     5041 gacatccttc gcattaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5101 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5161 acagcgatta atgaacaaaa accgaacttt aagattggaa ccttcatgat tccaggaaaa
     5221 gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc
     5281 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgttc agaagtcatg
     5341 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     5401 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     5461 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     5521 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     5581 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     5641 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     5701 agccttttac agttttacca actggacagg attgacttac aactacaaat ttgtcggctt
     5761 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     5821 aatcattacg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     5881 cttgaactct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     5941 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     6001 gattgggaat gcccttcata ttgaatttct ccaaaccagt cttttaggga ctaagtgggg
     6061 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6121 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6181 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6241 tatagtcttt atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat
     6301 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     6361 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     6421 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     6481 gcatgatgaa acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag
     6541 gatcggttct gattttagtg ccgctccttg ctaccctctt tagttccttc aaatccacta
     6601 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     6661 gtctcttagc tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt
     6721 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     6781 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     6841 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     6901 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     6961 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     7021 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7081 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7141 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7201 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7261 tctatctctt cttccaacgc catatcatcg caggaataag caacggggca gtgaagtaat
     7321 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
     7381 ttgaggttgt ggatgaaact gacgaagtca gtaaccatat ctacggtaag gcgacactga
     7441 cgtggtttga agagattttc gaagagtata acatgaattt gatttacgaa gccagatcat
     7501 atgagacttg gcttcaatta gaaaaaggag agtaatgatg ccaattcaaa ataaaaccat
     7561 gttgattacc tattctgata gccttggaaa taatcttaaa gacttatatg ataatttgga
     7621 agagcatttt ggagatgcta ttggaggagt tcacctttta ccatttttcc catcaacagg
     7681 tgatcgtgga tttgcgccag ttgactacga cgaagtggac tcagcttttg gtgattggga
     7741 ggatgttaag cgtttaggtg agaaatatta tcttatgttt gattttatga ttaatcatat
     7801 ttctcgtcaa tccaagtatt ataaggacta tcaagaaaaa catgaagcca gtgaatttaa
     7861 agatctcttt ttaaactggg ataagttttg gccagaaaac cgtccgacac agtctgatgt
     7921 agatttaatt tacaagcgta aggatcgtgc accaaagcaa gagattgtgt ttgaagatgg
     7981 ttcagtggaa catttgtgga atacctttgg tgaggagcag attgatcttg atgtgaccaa
     8041 agaagtaact atggaattta tccgtaagac cattcagcac ttggcaagta atgggtgtga
     8101 tttgattcgt ctagatgcct ttgcttatgc agtgaagaaa ttggatacta atgatttctt
     8161 tgtggaacca gatatttggg atttattgga caaagttcga gatatcgctg ctgagtatgg
     8221 gacagagatt ttacctgaga ttcatgaaca ctattcgatt cagtttaaaa tagcagacca
     8281 tgattactat gtttatgatt ttactcttcc aatggtgaca ctttatactc tttacagttc
     8341 cagaacagag cgtttggcta agtggttgaa gatgagcccg atgaagcaat ttacgacgct
     8401 agatacccat gatgggattg gagtagtaga tgtcaaggat atcctgaccg atgaggagat
     8461 tgactatgct tcaaatgaac tctataaggt tggagccaat gtcaaacgta agtactctag
     8521 tgccgagtat aacaacttag atatctacca aatcaattca acctactatt cagcgcttgg
     8581 agatgatgat gtcaagtatt ttctcgctcg tctaattcaa gcttttgccc caggtattcc
     8641 tcaggtttac tatgtgggtc tattagcagg caagaatgac ttgaaattat tagaagaaac
     8701 taaagaaggt cgaaatatta atcgtcatta ctatagcaac gaggaaatag caagagaagt
     8761 gcaacgacct gttgtgaagg cccttctcaa tctattttct ttccgtaacc gttcagaagc
     8821 ctttgatcta gaagggacta ctgagataga gacaccaaca gctcacagca ttgtaatcaa
     8881 acgtcaaaat aaagataagt ccgtaacagc agtagcagaa attgatttgc aaaatcagac
     8941 ttatcgggta attgagaatg gagttgaagt atcattttga agccttgata tggtggataa
     9001 aatagggttt ttattttgga aaacgtttcc tttgttttca aattgctaaa aaagtggtac
     9061 aatataggat agcttactat tatctgaatc agctgatttg gagagaaagg attcattttg
     9121 aaatcaatag gctttattga aaagctgaag gggttgtcta gtaaagagct gattttattg
     9181 ggaattatcc taagtatctt tttacccttt tatctttttg tagttgtact ctgtttatat
     9241 attatcagtt tgatttttac aggagacatg aaaagtattc ttcagaaaat gggggagcat
     9301 ccgatgctgc ttctttttct tagctatagt actgttatat ccattcttgc acaaaattgg
     9361 atgggtcttg tggcttcagt aggaatgttt ctatttacta ttttcttttt gcactatcag
     9421 tcgattttat cccataaatt ctttcgattg attttgcagt tcgtcttgtt tggtagtgtc
     9481 ttgtcagctg cttttgccag tttagaacat ttccaaattg tgaagaaatt taactatgct
     9541 tttctttcac ccaatatgca ggtgtggcat cagaaccggg cagaagtgac cttctttaat
     9601 cctaattatt atggaattat ttgttgtttc tgtattatga ttgctttcta tctgtttaca
     9661 acgaccaagt tgaattggtt gaaagtattc tgtgtgattg caggctttgt taatctcttt
     9721 ggtttgaact ttactcaaaa tcgaactgcc tttcctgcta ttatcgctgg agcaattatc
     9781 tatctcttta cgactattaa aaactggaag gccttttggc ttagtattgg ggtcttcgcg
     9841 attggtttga gtttcctctt ttctagtgat ttgggagttc gaatgggtac tttagactct
     9901 tctatggaag aacgcatttc tatctgggat gctgggatgg ccttgtttaa gcaaaatcct
     9961 ttttggggtg aagggccatt gacctatatg cactcttatc ctcggataca tgctccttat
    10021 catgaacatg cccacagtct ttatattgat acgattctga gttacggaat tgtgggtacc
    10081 attttattag ttttgtcttc tgttgctcct gttcgcttga tgatggatat gagtcaggag
    10141 tcggggaaac gtccgattat cggcctttat ctatctttcc ttacagtggt tgctgtgcac
    10201 ggaatttttg acttggctct cttctggatt cagtcaggct ttattttctt gctagttatg
    10261 tgcagtattc cattggagca tcgaatgttg gtatcggaca tgacggatta agttttataa
    10321 gtttgaaatc ttctaccttg ggtaggagat ttttttatac gatgggcatg tcgtgcatct
    10381 gaggtgtaag tcctctgtag ggatccacta ccggtgaata caatagcgct ccccaagcct
    10441 gactatcgtg aggtagcgga ttaaaatggt ctggggatag atcgttttaa gtctgacgca
    10501 ggaaataaga attgtcagag aaagcaatag tgaaatcgta ggctatgaat agaaacgtga
    10561 tagcgaggag catatagtgg ataaggtagc gagaaatttt aaagtataaa agatagtctt
    10621 aatctatata tgtaaatcac aaaagtaatt gaattcggaa taaggttggt gtgaaaagac
    10681 atagtaaact gaatcttgaa tactagaatg atacttctac aatattgtta taatttaatt
    10741 tgaattccaa aatcacattg ttccgtccgt atttcatttt actgtatgtc ttcctaaact
    10801 ccaaagtttc tgcgtcaaat ttcctatttt cactgtagtc tttgacactt cgaacgacaa
    10861 tttgaatcat atattcaaaa aaaaatgaaa aatttgtgcc aacaagccta aatattctga
    10921 aaatttgttt gatttttaat ggataatgtg atataatggt tgtcaatcta taattcacat
    10981 aaacagagga gtagaaaatg aaaaaaaatc gtgtatttgc tacagcaggt cttgttttat
    11041 tagcagcagg tgtacttgca gcatgcagtt cttcaaaatc atctgattca tcagccccta
    11101 aagcttatgg ctatgtttat acagcagacc cagaaacctt ggactacctg atttcaagta
    11161 aaaatagtac aacagtagtg acttcaaatg ggattgatgg tttattcact aacgataatt
    11221 acggtaatct tgctcctgca gttgcagagg attgggaagt ctctaaggat ggtttgacct
    11281 acacttataa gattcgtaaa ggggttaaat ggtttacctc tgatggagaa gaatatgcag
    11341 aggtgacggc taaagatttc gtgaacggtt taaaacacgc agcagataaa aaatcagaag
    11401 ctatgtattt agctgaaaat tcggttaaag gcttggcaga ttatctatca ggaacttcaa
    11461 cagatttttc aacagttggt gtcaaggcgg ttgatgatta tacgttacaa tacactttga
    11521 accagcctga accgttctgg aactctaagt tgacctattc tattttctgg cctctgaatg
    11581 aagaattcga aacatcaaaa ggaagcgatt ttgctaaacc aacagatccg acatccttgc
    11641 tttataatgg tccattcttg ttgaaagggt tgactgcaaa atcttctgta gagtttgtaa
    11701 aaaatgagca atattgggat aaagaaaatg tccacctaga tactatcaat ctagcttact
    11761 atgatggatc agatcaggag tcgctagagc gtaacttcac tagtggagct tatagttatg
    11821 cccgtcttta ccctaccagc tccaactatt ctaaggttgc agaagaatac aaggacaata
    11881 tctattacac acaatcaggc tctgggattg ctggtctggg tgtgaatatt gatcgccaaa
    11941 gttacaacta tacttctaaa actacagatt cagagaaagt agctactaag aaggcattgc
    12001 ttaacaaaga tttccgtcaa gccttgaatt ttgctcttga tcgctcagct tactcagctc
    12061 aaatcaatgg taaagatgga gcagctttag cagttcgtaa tttatttgta aaaccagact
    12121 ttgtttcagc tggtgagaag acctttggtg atttagtcgc tgctcaactt cctgcttatg
    12181 gtgatgagtg gaaaggtgtg aatttagctg atgggcagga tggtttattc aatgctgaca
    12241 aggccaaggc agagtttgcg aaagctaaga aagctttaga agcagacggc gttcagtttc
    12301 ctattcatct ggacgttcca gtagaccaag catcaaaaaa ctacatatct cgtattcagt
    12361 cctttaaaca atctgtagaa acagttcttg gtgttgaaaa tgtcgttgtt gatattcaac
    12421 aaatgacaag tgatgaattc cttaatatta cttactatgc tgccaatgct tcatctgagg
    12481 attgggatgt atcgggagga gtttcatggg ggccagacta tcaagaccca tctacttacc
    12541 tggatatttt aaaaacaact agcagtgaaa ctacaaaaac atatttagga tttgataatc
    12601 caaatagccc ttcagtagtt caagttggtt tgaaagaata cgataaatta gttgatgaag
    12661 ctgccaaaga gacaagcgac ttgaatgtcc gttatgaaaa atatgcagcg gctcaagcat
    12721 ggttgacaga tagttcactc tttattcctg ctatggcttc ttctggtgca gcaccagtgc
    12781 tttcacgaat tgttccattt actggagctt ctgcgcaaac aggctctaag gggtcagatg
    12841 tttacttcaa atatttgaaa ttacaagata aagtggtgac taaggaagag tatgaaaaag
    12901 ctcgtgaaaa atggttgaaa gaaaaagctg aatcaaatga gaaagctcaa aaagaattgg
    12961 caagtcatgt gaagtaaata atttctaata gaactttctc tccatgagga gaaggttctt
    13021 ttgggatttt taaaggaaat aatatgaaaa aatatatttt tatgcgtgtt ttgcggtcat
    13081 tggtttcgat tttcttagta acgactttga cctacacgat tatctatacc ttggttcctc
    13141 gaaaattgat tttcaagcag gatcctaact ataataaaat tgcaacaacg gctgataaac
    13201 gtgataacta tgaaaatact gtgtttgagc gtatgggcta cattgagtat tacgatacta
    13261 aagagttgca agaaaaggca agtagcatgg attcttctgt aacagtagaa gcaaatgcga
    13321 ccaataaagc tatttatgaa aagtacatca atcaattagg tcatggttgg actttgggag
    13381 aatttactga aagtggtcaa ttctatgcta ctcgtgaaat tccaattttt gaacgtgttt
    13441 ttcacttcta tgctaacttg attgacattg accatacaaa taaaatccaa gaccctgaaa
    13501 atccagactt gaaacgctac cttcgttttg aaaatgatcc agctatcgga tggtcattgg
    13561 tcggttcagg aactaaacat aaatatctct tgtactttaa cagtcagttc ccatttgttc
    13621 atcaaaactt tgtgaacttg aatttaggtg actcttaccc aacctatgct aatacaccag
    13681 ttcttcaggt tattactcaa ggtcaaggac aaaccaaaac tgcccaagtt cagttcccaa
    13741 caggtaagaa aacgtcttct gtaaatattt actcaagaac ctacaagtca cctagtcagg
    13801 ctgactctcg tgaagtagct agctatggga aagatgatcc ttatacagcg actgaaagta
    13861 attaccaata tccatctatg attgtcagct ctgctattac tggtttgatt ggtttggttc
    13921 ttgcctatgc tcttgccgtg ccacttggtt cagccatggc tcgtttcaag aacacttgga
    13981 ttgatagcct ctcaacaggg gctttgacct tcttgcttgc tcttccaacg attgccttgg
    14041 tttacatcgt tcgattgatt ggatcatcta ttgcccttcc agattcattc cctatcttgg
    14101 gagctggaga ttggcgttct tacgttttac cagcagtcat ccttggtttg ttgggtgctc
    14161 ctggtacagc catttggatt cgtcgttaca tgattgactt gcaatctcaa gactttgttc
    14221 gtttcgctcg tgcaaaaggt ttgtctgaaa aagaaatttc aaacaaacac atctttaaaa
    14281 atgccatggt tccgctggtt tcaggaattc ctggtgccat cattggggtt atcggtggtg
    14341 caacccttac tgaaacagtc ttcgccttcc caggtatggg taaaatgttg attgactctg
    14401 taaaagcatc taataactct atggtcgttg gtcttgtctt catctttaca tgtatttcta
    14461 tcttctcacg tcttttggga gatatttgga tgactattat tgacccacgt attaaattga
    14521 ctgagaaagg aggcaaataa tgtctacaat cgataaagaa aaatttcagt ttgtaaaacg
    14581 tgacgatttt gcctctgaaa ctattgatgc gccagcatat tcttactgga aatcagtgtt
    14641 taaacaattt atgaagaaaa aatcaactgt agtcatgttg ggaatcttgg tagccatcat
    14701 tttgataagt ttcatctacc caatgttttc taagtttgat ttcaatgatg tcagcaaggt
    14761 aaacgacttt agtattcgtt atatcaagcc aaatgcggag cattggttcg gtactgacag
    14821 taacggtaaa tcgctctttg acggtgtctg gttcggagct cgtaactcca tcctcatttc
    14881 tgtgattgcg acagtgatta acttggttat cggtgttttt gtcggtggta tttggggtat
    14941 ttcaaaatca gttgaccgtg tcatgatgga agtttacaac gtcatctcaa acatcccacc
    15001 tcttttgatt gttattgtct tgacttactc aatcggagct ggattctgga atctgatttt
    15061 tgccatgagc gtaacaacat ggattggtat cgccttcatg atccgtgtgc aaatcttgcg
    15121 ctatcgtgac ttggaataca acttggcatc acgtactttg ggaacaccaa ccttgaagat
    15181 tgttgccaaa aatatcatgc ctcaattggt atctgttatt gtgacaacca tgactcaaat
    15241 gcttccaagc tttatctcat acgaagcctt cttgtctttc ttcggtcttg gattaccgat
    15301 tacagtgcca agtttgggtc gtttgatttc ggattattca caaaacgtaa caaccaatgc
    15361 ttacttgttc tggattccat tgacaaccct tgtcttggta tccttgtccc ttttcgtagt
    15421 tggtcaaaac ttagcggatg ctagtgatcc acgtacacat agataggagt agaaatgaca
    15481 aaagaaaaaa atgtaatttt gactgctcgc gatattgtcg tggaatttga cgttcgtgac
    15541 aaagtattga cagccattcg cggcgtttcc cttgaactcg ttgaaggaga agtattagcc
    15601 ttggtaggtg agtcaggatc aggtaaatct gttttgacaa agaccttcac aggtatgctc
    15661 gaagaaaatg gtcgcattgc ccaaggtagt attgactacc gtggtcagga tttgacagct
    15721 ttatcttctc acaaggattg ggaacaaatt cgtggtgcta agattgcgac tatcttccag
    15781 gacccaatga ctagtttgga ccccattaaa acaattggta gtcagattac agaagttatt
    15841 gtaaaacacc aaggaaaaac agctaaagaa gcgaaagaat tggccattga ctacatgaat
    15901 aaggttggca ttccagacgc agatagacgt tttaatgaat acccattcca atattctgga
    15961 ggaatgcgtc aacgtatcgt tattgctatt gcccttgcct gccgacctga tgtcttgatc
    16021 tgtgatgagc caacaactgc cttggatgta actattcaag ctcagattat tgatttgcta
    16081 aaatctttac aaaacgagta tcatttcaca acaatcttta ttacccacga ccttggtgtg
    16141 gtggcaagta ttgcggataa ggtagcggtt atgtatgcag gagaaatcgt tgagtatgga
    16201 acggttgagg aagtcttcta tgaccctcgc catccatata catggagtct cttgtctagc
    16261 ttgcctcagc ttgctgatga taaaggggat ctttactcaa tcccaggaac acctccgtca
    16321 ctttatactg acctgaaagg ggatgctttt gccttgcgtt ctgactacgc aatgcagatt
    16381 gacttcgaac aaaaagctcc tcaattctca gtatcagaga cacattgggc taaaacttgg
    16441 cttcttcatg aggatgctcc aaaagtagaa aaaccagctg tgattgcaaa tctccatgat
    16501 aagattcgtg aaaaaatggg atttgcccat ctggctgact aggaggaagg aaatgtctga
    16561 aaaattagta gaaatcaaag atttagaaat ttccttcggt gaaggaagta agaagtttgt
    16621 cgcggttaaa aatgctaact tctttatcaa caagggagaa actttctcgc ttgtaggtga
    16681 gtccggtagt gggaaaacaa ctattggtcg tgctatcatc ggtctaaatg atacaagtaa
    16741 tggagatatc atttttgatg gtcaaaagat taatggtaag aaatcgcgtg aacaagctgc
    16801 ggaattgatt cgtcgaatcc agatgatttt ccaagaccct gctgcaagtt tgaatgaacg
    16861 tgcgactgtt gattatatta tttctgaagg tctttacaat caccgtttat ttaaggatga
    16921 agaagaacgt aaagagaaag ttcaaaatat tatccgtgaa gtaggtcttc ttgctgagca
    16981 cttgactcgt taccctcatg aattctcagg cggtcaacgt caacgtatcg gtattgcccg
    17041 tgccttggtc atgcaaccag actttgttat tgcagatgag ccaatttcag ccttggacgt
    17101 ttctgtacgt gcccaagtct tgaacttgct caaaaaattc caaaaagagc tcggcctgac
    17161 ctatctcttc atcgcccatg acttgtcggt tgttcgcttt atttcagatc gtatcgcagt
    17221 tatttacaag ggtgttattg tagaggttgc agaaacagaa gaattgttta acaatccaat
    17281 tcacccatat actcaagcct tgctttcagc ggtaccaatc ccagatccaa tcttggaacg
    17341 taagaaggtc ttgaaggttt acgacccaag tcaacacgac tatgagactg ataagccatc
    17401 tatggtagaa atccgtccag gtcactatgt ttgggcgaac caagccgaat tggcacgtta
    17461 tcaaaaagga ctaaactaat aatggtttta taatttccat gtcaattttt atgggaatta
    17521 taaaactttt ttgttggact gatttgaaaa actttgaaag cttcctgaaa ga
//
LOCUS       DAVAZV010000048        17282 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVAZV010000048 DAVAZV010000000
VERSION     DAVAZV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17282
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.048"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..692)
                     /locus_tag="VQT46_001590"
     CDS             complement(<1..692)
                     /locus_tag="VQT46_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2371590.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSYRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELISENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDG"
     gene            complement(803..1057)
                     /locus_tag="VQT46_001591"
     CDS             complement(803..1057)
                     /locus_tag="VQT46_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371591.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRITNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(1415..1948)
                     /locus_tag="VQT46_001592"
     CDS             complement(1415..1948)
                     /locus_tag="VQT46_001592"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371592.1"
                     /translation="MTIFKEQESEKVAEFLDILDNLKDLPIVYIDETGINRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(1935..2261)
                     /locus_tag="VQT46_001593"
     CDS             complement(1935..2261)
                     /locus_tag="VQT46_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371593.1"
                     /translation="MAYNTDFKQGALDSIKGGHRHVEAAKVFWCWRQNSLHVGKERRE
                     QRNLERKKRVVKKRKIPLEELKAFVEAHPDAFLREIAAHFDCAVPSVWAALKQIKVTL
                     KKDDDL"
     gene            2495..4213
                     /locus_tag="VQT46_001594"
     CDS             2495..4213
                     /locus_tag="VQT46_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET2371594.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            4324..4671
                     /locus_tag="VQT46_001595"
     CDS             4324..4671
                     /locus_tag="VQT46_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2371595.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     AGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(4949..5785)
                     /locus_tag="VQT46_001596"
     CDS             complement(4949..5785)
                     /locus_tag="VQT46_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET2371596.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(5798..6427)
                     /locus_tag="VQT46_001597"
     CDS             complement(5798..6427)
                     /locus_tag="VQT46_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET2371597.1"
                     /translation="MLELRNINKVFGDKQILSNFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLDNLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(6437..7078)
                     /locus_tag="VQT46_001598"
     CDS             complement(6437..7078)
                     /locus_tag="VQT46_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET2371598.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(7224..8453)
                     /locus_tag="VQT46_001599"
     CDS             complement(7224..8453)
                     /locus_tag="VQT46_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET2371599.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEESENLLT
                     KWMIARSYQEMDDLDTAYEHYQELIGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(8443..9609)
                     /locus_tag="VQT46_001600"
     CDS             complement(8443..9609)
                     /locus_tag="VQT46_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET2371600.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            9753..10766
                     /locus_tag="VQT46_001601"
     CDS             9753..10766
                     /locus_tag="VQT46_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET2371601.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(10811..11230)
                     /locus_tag="VQT46_001602"
     CDS             complement(10811..11230)
                     /locus_tag="VQT46_001602"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET2371602.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDQVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQT46_001603"
     CDS             complement(11241..12647)
                     /gene="atpD"
                     /locus_tag="VQT46_001603"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET2371603.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(12733..13611)
                     /locus_tag="VQT46_001604"
     CDS             complement(12733..13611)
                     /locus_tag="VQT46_001604"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET2371604.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(13627..15132)
                     /locus_tag="VQT46_001605"
     CDS             complement(13627..15132)
                     /locus_tag="VQT46_001605"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET2371605.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALIHGFLDTVPV
                     DDIVRFEEEFHAFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(15147..15683)
                     /locus_tag="VQT46_001606"
     CDS             complement(15147..15683)
                     /locus_tag="VQT46_001606"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET2371606.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQT46_001607"
     CDS             complement(15683..16177)
                     /gene="atpF"
                     /locus_tag="VQT46_001607"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET2371607.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQT46_001608"
     CDS             complement(16191..16907)
                     /gene="atpB"
                     /locus_tag="VQT46_001608"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET2371608.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(16942..17142)
                     /locus_tag="VQT46_001609"
     CDS             complement(16942..17142)
                     /locus_tag="VQT46_001609"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET2371609.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         5222 a         3785 c         3096 g         5179 t
ORIGIN      
        1 ccgtcagtag tagtcatgct actgagtttt ttatctgtga cattgtagct ggtaccaatc
       61 agttgttttt tattggtaat gtaggttccg tcactttctt tttctccaat tccagtatca
      121 tttttcaatg atagcaaacg cccttgttca tcaacatagc gaactttcac attttctgag
      181 attagttctg ccaattctga ggtttttttc tttttcttga tttcttcggt tattttccct
      241 ttctcttctt cgggaatatt tagttttgga atgatttttt caacaacggt tcgtgatggt
      301 tccacagtat cttggatgac tgaaaagtca gctagaattg ggagattata ctgaacacgg
      361 taactttgag tgtttactcc tactctttca ttattctctg aaaatacttg tacggtataa
      421 gaaacaacat cttttcctaa tagaacatcc ccagtagaga aatagccgcc ttttcctagt
      481 ttgctatctc cagagcccac ttctttccta attttatcag atagtttttt accagtcagt
      541 acattcgttc gcacaatccc tttgtctacc cctacaaagt gggagaactt tttgaactct
      601 tcagaaccag atctagccca accattatta agggcatttg cttttgtatt tgtattctct
      661 ctcaaaggtt tggcgattag aattatattc atcggcactt agagttgctg ctatatctga
      721 ctcttgaata ccaacttcct tactaccatt tctagcggca gtatatgtgt atttatctgt
      781 ttctacttct agctgattat ccttaacatg ataggtaatt ttctcctggt ataagagtct
      841 tcagtagttt atatactctg tcatcatctt tagctttaga agcagctgag tttagccaag
      901 ttggggtatt aggagtatct ttatcaacct gtttcaagac attattcaag tcatttgcta
      961 gcctattggt tatcctcact gtgaaagttt tcttccagtc tgaaccactt ttattagact
     1021 tagatatgct catgaaatcc tggtcaacat tcaacacaat atcgccttgt tttttagcat
     1081 cttccgttgc ttctgcttca aattgatcat ggagtttttg ttgctctggt gtatagtttt
     1141 tttatttaca cgatttaatg tactattttt tattttagta ttaagaactc cattaatacg
     1201 atttttaaac tctgcttcaa aaaatccctt aatttgttgg tgcgcaagtt caacattcaa
     1261 acctttctta tacaagtctt cattctgata caagtcttca ttctgaacga tttcggctac
     1321 acggtgaatg gtttgatcgt ataccgtctt ctcttaacca gcagtatcct tagttttaat
     1381 gactactcga taggttcctt tagaaccgtt atagtcatct agttttaaaa aagcattcca
     1441 aacattcaaa aatagttgga acttccctta ataaatccgt cactttcttt ttcaagatag
     1501 cccaagcttg ctcaatagga ttcaaatccg gtgaataagg tggtagaggt aagaaaaagt
     1561 gtttatcttg gatgcagagt tcatccaaaa tgttcttggg atgaaaacta gcattgccca
     1621 tgacaataac atgaggtgtc ttcaaagcag gtaggagttg cgttttgaac cactccacaa
     1681 agaaatcgct tgtcatgctt ttcttgtaaa tcatgggagc tataaactct ccgtctactt
     1741 gtcctgcaac aattgaagtt cgctcaaaac gacgtccgct aatcttttca tagactttct
     1801 cccctctagg agcccctgca taaggacgat agaggtagcg gttgattcct gtttcatcaa
     1861 tatatacgat tggtaaatct tttaggttat ccaaaatatc aagaaactca gcgactttct
     1921 ctgactcttg ttccttaaag atcgtcatct ttttttaaag tgaccttaat ctgctttaaa
     1981 gctgcccata ctgaaggaac agcacaatca aaatgtgccg caatttcccg taaaaaagca
     2041 tctggatgag cctctacaaa ggctttcaat tcttctaaag ggatcttacg ctttttgacg
     2101 actcgctttt tccgctctaa gttcctttgt tcacgtcttt cttttcccac gtgaagagag
     2161 ttctgacgcc aacaccaaaa aactttggcc gcctcgacat gtctgtgccc tcctttgatg
     2221 gaatctaatg ctccttgttt aaaatcagta ttatatgcca tagctttatt agaccatgct
     2281 tattttaaac taagcaacta tatcaatgtt ttgttatgag aagacttact ttttttactg
     2341 aaattgaatt tttcctagcc tcaacatcat ataaccccaa aattcaatct gacctggttt
     2401 gaagagatgt tcgaagcaga taaggtttta ctaaaactaa aaaaaatgat ataatcaaac
     2461 tgattaaatg ttttaaaaat aaaggagaat ttgaatgtct taccaagaaa attaccagaa
     2521 atgggttgat tttgtggagc ttcctgacta ccttcgtcaa gatttggaaa atatggacga
     2581 aaaaactaag gaagatgcct tctatacaaa tcttgaattt ggtactgcag gtatgcgtgg
     2641 cttggttggt gctggtacaa accgtatcaa catctacgtt gttcgccaag ctactgaagg
     2701 attggctcgt ttgattgagt caaaaggtgg aaacgagaaa gaacgcggtg tagcaattgc
     2761 ctacgatagc cgtcacttct cacctgagtt tgcctttgaa tctgcggcag ttcttgctaa
     2821 acacggcatc aaatcttacg tatttgaaag ccttcgtccg actccagaac tatcatttgc
     2881 agttcgtcat ctcaactgtt tcgcaggtat catggtcaca gccagccaca accctgctcc
     2941 atttaacggt tacaaggttt acggtgaaga cggtggacaa atgcctccac acgatgcgga
     3001 cgctttgact acttatatcc gtgcaatcga aaacccattt gcagttgaag ttgctgatgt
     3061 ggaaactgaa aaagcttctg gcttgattga agttatcggc gaagctgttg acgtagaata
     3121 ccttaaagag gttaaggacg taaacatcaa cccagccttg attgaagaat ttggtaaaga
     3181 catgaagatt gtctacacac cacttcatgg tactggtgaa atgttggctc gtcgtgctct
     3241 tgcccaagca ggatttgact ctgttcaagt tgttgaagcg caagcaactg ctgacccaga
     3301 cttctcaact gtaacatctc caaacccaga aagccaagca gcctttgccc ttgctgaaga
     3361 acttggtcgt caagttggtg cagatgttct tgtcgcaact gacccagacg ctgaccgtgt
     3421 tggtgttgaa gttcttcaaa aagatggtag ctacctcaac ctttcaggta accaaatcgg
     3481 tgctatcatg gctaaataca tcttggaagc tcacaaaaac gctggaactc ttcctgaaaa
     3541 tgccgctctc tgcaaatcta tcgtttcaac tgacttggta acgaagattg ctgaaagcta
     3601 cggcgcaact atgttcaacg tcttgacagg tttcaaattt atcgctgaaa aaatccaaga
     3661 attcgaagaa aaacacaacc acacttacat gatgggattt gaagaaagct tcggttactt
     3721 gattaaacca tttgtacgtg ataaagatgc catccaagcc gttcttgtcg ttgctgaact
     3781 tgctgcctac taccgttctc gtggtttgac acttgctgac ggtatcgaag aaatctataa
     3841 agaatatggc tactacgcag aaaaaacaat ctctgttact ctttcaggtg tcgatggtgc
     3901 tgaacaaatc aaagcgatta tggctaaatt ccgcaacaat gctccaaaag aatggaacgc
     3961 aacagctatc actgtcgtag aagacttcaa ggcacaaact gctactgttg ctgacggtac
     4021 tgttacaaac ttgacaactc ctccaagtga tgtgttgaaa tacacacttg ctgacggttc
     4081 atggattgcc gttcgccctt caggtacaga accaaaaatc aagttctaca ttgcagttgt
     4141 aggagaaacc aacgaagaat cacaagctaa gattgctaac atcgaagcag aaatcaatgc
     4201 atttgtaaaa taaagaccta taaaagatga gaccaaccaa cctcatcttt tttcgtatca
     4261 aatctaagca attttagaaa ctttatggca tactagactt atcaatgaaa gcgaggtaat
     4321 ctcatggaac aatttttaga taacatcaaa gaccttgaag tcactacagt tgtgcgtgcg
     4381 caagaagctc ttgataaaaa agaaactgca accttcttta tcggtcgcaa aacttgccct
     4441 tactgccgta aatttgcagg tacattgtca ggtgtcgtag ctgaaaccaa agctcacatt
     4501 tacttcatca atagtgaaga accaagccaa ctcaatgatt tgcaagcatt ccgctcacgc
     4561 tatggaatcc caactgtacc aggttttgtt catattacag atggacaaat caacgtccgt
     4621 tgcgactctt caatgtcagc acaagaaatc aaagatttcg caggattgta aaaaatcagc
     4681 taacaagtct taaaatcaca aaaacgcata atgtaaggtg caaaaacctt gatattatgc
     4741 gttttattgt tcctaaaaca gttacatcag catttcatta cagaacattt taattttgga
     4801 agtcaaatca atttttaaca atgttttaga aatcacagtg ggctattcca tattaaatta
     4861 tccagattca atcgctatta tcgttttcct agattacaaa aaaactgcgt tttgctaatc
     4921 aaaacgtagt ctcagccact attttatctt actgtccttc ttttacttct ttggttgcta
     4981 catcttctcc aaaccatttt tggctgattt cttggaactt gccgtccttg taaagactag
     5041 aaaaagcttc atttatcttc ttaaccaagg ttgtatcttc cttacgggct ccaaccgcaa
     5101 aagcttctgt ttctagtcca actgtaaaga cattataatc gtttaaaaca ccttctgctt
     5161 ctaaataata gtttgcatag acacggtcaa tcaatagacc atcaattcga tcgtttttca
     5221 aatcaatcaa ggcttcatta aaggtttggt attgattcgc ttccttatta gcgacaatat
     5281 tcttcaaaat ttctggattt gcttcaaagt ccgcataacc agatgaacca gcttgagctc
     5341 ctaatgtctt tccagtcata tcctttgcag tcgtgatacc agatgatttc ttcgtaacca
     5401 atacctgctc attcttcata tatgagttac tgaaagccac cttttcacgg cgttcgtctg
     5461 tagcggaata gccattccaa atcagatcaa tcgttccttt tgtcaattca gcttctttca
     5521 aatcccaatc aatcggttgc caatttaccg tgattccgta tttttcaaaa acagctgtag
     5581 ctaaatcaat atcaaatcct gcataagaac catctttctg agcaaatccc attggaacaa
     5641 aagtactatc aaatccaata gtaatagact tgttagactg gtactttgac caattatctc
     5701 cactagtttc gctagaattt ttcccacaag ctactaagaa caaagcagtc atcagactga
     5761 ctaatacaag catccatttt ttcatccatt tttcctccta tttaggttct actttcaata
     5821 atacatctgc gatattttca gcaaactgca aatcatgggt aaccacaatc tgggtcatcc
     5881 caagttccct attttgcaag attagcttct ccacttccaa acgtaattct ggatccaggg
     5941 cagaagttgg ttcatcgtag ccaatgattt ctgggtcaat catcatagca cgcgccaaag
     6001 ccacccgctg cttttgccca ccagatagtg agaaaggata ggcctctgcg tgtcctccta
     6061 gtcctaactg ttccaagagt ccactcgcct tcttctcagc ctcttcctgc ttcattccca
     6121 tggtcttcac aggcgataag gtcaaattgt ccagaactga taaatgaggg aacagttgaa
     6181 aatcttggaa tacaaatccc agtagattgc gcttctgcaa ttcatccagc tctaaaggtt
     6241 gtccattata aaagatttgc cctgaatcaa tggtttcaag acctgcaagc atacgtaaaa
     6301 gagttgtctt acctccacca gaaggtccaa cgatagccag gatttgcttt tcaggaatac
     6361 ttagactgaa attagacagg atttgtttgt ctccaaagac tttattgata tttcgtaatt
     6421 ctaacatggc agcctcctat ctataataac tatacttctt ctcaactttt ttggaaataa
     6481 ttgtcacaat cccaatcaaa atcaaataaa tggctcctgc caagaacata ggaactagac
     6541 tagcatcgcg gttagcagct gttcgactag ccaagataag gtctgaaatt ccgagagcat
     6601 agaccaaaga agtatccttg accaaactca taacttcatt aaagacacta ggaagaacga
     6661 tcttggtcac ttggggcaag ataatatagc gcactctgtc aaaagggcta aacttcaaga
     6721 ccttggcggc ctcatactgt cctcttggaa tagtgtcaat tcccccacgg aaaatttctg
     6781 caaagtaagc tgcatagttg agaacaaagg caataatagc tgcaggaagg cggtctaaac
     6841 gaatcccaat acttgggagc acataataga taaaaatcag ttgcaagagt aagggggttc
     6901 ctcgcataac ccagatgtaa atgttaatca gataatggag gggcttccaa tggacttgca
     6961 aggcaaaggc aatcaaaacg cccaagggaa tcgaaaatag caagaccagt gcaaagacct
     7021 gtacagtcgt gctcgcacca ttcagtaaac tcggtaatat ctcaaataaa taagacatac
     7081 tgcacctcct aaaagtaatt gttcctatta tagcatgaat aaacaagatt accaagtatt
     7141 tttgtaaaaa gattctacca tatacaaata aaaaccgtag ctatcaaaag agataaacta
     7201 cagttctata tgtttaaaca ttcttacaat ctctcaaaca gttcttgcat ttgcacatca
     7261 tctggaacca gttttaagta agtgtgagca tggacttttg cttcttcaaa atgtcccaat
     7321 tcacgcaaga gatagatata gtgttccaga aattctggat tgtccttcaa atctcctatc
     7381 aactcttgat aatgctcata agcagtatcc aaatcgtcca tttcttgata agaacgagca
     7441 atcatccact tggtcaaaag attttctgac tcctcactct gcaagtctag aatatcctca
     7501 taacgctcct gctccagata aatagtggct aaacgaagca agatttcttc tgtatcctca
     7561 gcgtcttctt ttgcagtaag gagataattt tctgcaccac tagcatcatg caattcataa
     7621 gaaaattgtg aagcagctag caagaggcga gtttcaaagg gatttttctc taatccttgc
     7681 ttagcgatac gcagggcttc ttgaacttga tgttccttat gtaaagcctg actgtaccca
     7741 tactcatagc cttcaaagtc aggagaaatg gtatcaagct gcttaaagta gagggtggct
     7801 ttttgatatt cttcttgatc aaaataaaga ctggccaact caaaagctgt taagtcatcg
     7861 tattctaact ccagggcttt ttctaaaaac tcagtagccg tttcaaattt ccctaactga
     7921 gcataggcaa agccaattcg ttgataggtg gaaatgcccg tttgctcata aatcgagcga
     7981 ttatctaact gggcataggc ttgaatagcc gcttggtaat tttccaactc actatccaac
     8041 tctgccaaac ccaatatcaa gagagaatcc tctgagtagg tcaaggcctc caataatttc
     8101 tcacgtgcca catctgtcaa accttccagc tggtaaaggt ctgccttcag agccaaagac
     8161 gagacatacc agtcactgtc agcttggatt tcctcaagat aggtaaaggc ttcttctatt
     8221 tgaccatcct cgctagcaat tgcagctaga ttaagatgaa cctctggaaa atcctctaca
     8281 attttcaggt aaatttcctt ggcctgagga tagaaaccaa tcccttcaag ataagttgcc
     8341 aactcataca gaagatcact tgaatcattt tctaaagctt tggcgaaata atgctcagcc
     8401 ttagttaaat cttgctcctc caaagcctgt aacatctgtt gactattgtt cactcttgac
     8461 ttcctcaccc tctaattcat atagaccact gactacctta taccattcga aaatggctga
     8521 aatgacaacc ttagcagagg cataaaccgg aataccaagt aaaactcccc agataccaaa
     8581 catagatcct gaagttaaca aaacaaagag aacattaata gggtggatgt ttaattgact
     8641 tcccaaaatc aatggagaga caaaacggcc ttcaatagtt tgttctacga taaagacaat
     8701 cactactttc aaaagcatga ctggaccagc aatcaaaccc aatactagag caggaagcat
     8761 ggctagaaag ctaccaagat aagggaccag atttaaaata ccagcagtaa cccccagcgt
     8821 aaccgcatag cgtagaccaa taatcttgaa gaagatgata aacattactg ctacaataat
     8881 agccactgtc acttgccctc gaacatagtt ggacaactgt tgattcacat ctgataaaac
     8941 ttgtccaaca ggttccttca attttcttgg aatgaattgg gtcaaatagt tacgcaagcc
     9001 tttcccatca cgcaagagat aaaagagcat gaaaggaacg ataatcaagg caacaatcac
     9061 ttgagaagct ccgctaataa aggcactcac ccagttgact gcctgagatg aaaccttact
     9121 tgccaaaact gtagcctggc tagaaaaatt ggtcaaaact tgctctaatt gaggtctgaa
     9181 atcatctggc aggtgctggg ctaccaatcc attaacaatc ctatctatat cttctaagta
     9241 aacaggaacg tttcttgcaa aggtcaaaac ctgacgttgc agatttggaa tggcgactgc
     9301 caagccccaa atgataaaga gagcgatgat aacaaagaca atagtgatag ctataacacg
     9361 attaacctta tgcttctcca tccaatcaac aataggattc aacaaataat ataacaaacc
     9421 agacaaaatg actggcaaca tcacaactgc taaaaagtct aaaacaggtg aaaatagaaa
     9481 actaatctta cttaaaataa aaagattcag tcccaataat aaggttacta aaaataccgt
     9541 aattgccttg ttatctaaaa accacttgaa aaaccaagat aggctaaaat gtttctcttt
     9601 ttgctccata aatacttcct ttctattgtt ctctcattat accatttttg aaacaaaata
     9661 actctttttt aaagtgctta catctaattg gatatcttta atttacttgt ttttgtgata
     9721 taatagtctt atctttacac agaggtatag taatgaaaga aactgtttat tttggaactt
     9781 atacacgtcg tacttctcaa gggatttaca aggcagactt tgatacagaa actggtcagc
     9841 tttcaaatct agaacttttt gcagctgagc caagtccaac ctaccttgcc tttgaccagc
     9901 accaacattt atacactgtt ggtagccaag acgataaggg gggaattgca gcctatcaaa
     9961 ctgacgggac tgtgttaaat catgttgttg aagaaggagc tccccactgt tatgttgctg
    10021 tcgatgaaaa gcgtgatttg gtttacgcag ccaactatca caagggacaa gtccttgttt
    10081 ataaacgcca ggaagatggt agtcttctac ttagtgatat ggatcaacac agtggccaag
    10141 gtccacatga aaatcaagct tccccccatg ttcactatac agatttaaca cctgaccact
    10201 atctagtgac ctgcgacttg ggaactgacc aagtcatcac ctatgacctc gatcaagaag
    10261 gaaaattatc taagctctat acctatcaca gcaagccagg agcaggctca cgccatatca
    10321 ttttccataa ccactataaa atcgcttatc tcatttgtga actcaatagt actatcgaag
    10381 ttttaatcta cgatggcgtt ggcgaatttg aacgtatgca ggtcatttca actttaccgg
    10441 aagcttacga aggctttaat ggaaccgctg ctattcatct ctctaaagac ggtaaatacc
    10501 tctacgcttc taaccgtggc catgattcta tcgcagtata taccatcctt gcggacggta
    10561 gcttagagtt attagaaatc gttccaacgc atggtcagac tccacgtgat tttgatttga
    10621 cacccgacca aaaatttctc attgttgtcc atcaagactc tgacaatgca actgtcttta
    10681 aacgtaattg tgacaatggt cgtctagcag aactctccaa cgacttccat gttcccgaag
    10741 cagtctgcat ccgttttgct ccttaaaaca ccataaaaaa tgaacttggt attttcaagt
    10801 tcattttttc ttatagtcta tttccgacat taatacggtt aatagcacgt tgcaaagcaa
    10861 tcttagcacg acgttcttgg tcaatcaaat gtttgtcttg tgcttcttca attgcacgtt
    10921 ctgcacgaag tttggcacgt tctgcacgac tgatatcgat atcacgagca cgttctgcag
    10981 agtcagcgac gattgtgatc atatcattgg caatttcaat aacaccaccg tttactgcaa
    11041 tccagttcac ttgatcttta tcatcgatac gttttacctt tacttcatca actgctaaaa
    11101 ccgcaatcat attttcatgt cgtggcaaga tccccatctc accatccaga gttcgaaccg
    11161 atacatagct ggcatggtga tcatagacga gaccatctgg tgtcacgatc tggacagtta
    11221 actgagccat agttcacctc ttaaaatccc attttttcag cttttgcaat cacatcttcg
    11281 atagaaccta caccacggaa ggcatcttct ggcaagtggt cgtatttacc atcaaggatt
    11341 tccttaaagc cacgtacagt ttcagcaact ggaacataag aacctggctg accagtaaat
    11401 tgttccgcaa cattgaagtt ttgtgacaag aagaactgga tacgacgggc gcgagcaacc
    11461 aaggtctttt cttcatcaga aagttcatcc ataccaagga tagcaatgat atcttgcaat
    11521 tcatggtaac gttgaaggac acgttttact tcagcagcaa ctgcatagtg ctcttctcca
    11581 acgatttcag gtgccaaggc acgtgagctt gaagcaagtg ggtcaacggc tgggtagata
    11641 cccaattgta ccaacttacg ttccaagttt gttgttgaat ccaagtgagc gaaggctgtt
    11701 gctggcgctg ggtcagtata gtcatccgct ggcacataga tagcctggat agaggttaca
    11761 gaacccttct tggttgatgt gatacgttct tgcaattgac ccatttccgt agcaagtgtt
    11821 ggttggtaac caacggctga tggcatacga cccaaaaggg cagatacttc tgaaccagcc
    11881 tgagtgaaac ggaagatatt atcgataaag agaagcacgt cttggccttc cacatcacgg
    11941 aagtattcag cgattgtcaa accagtaagg gcaacacgca tacgtgctcc tggtggctca
    12001 ttcatctgac caaagaccat ggctgttttc tcgataacgc ctgattcttt catttcccag
    12061 taaaggtcat tcccctcacg agtacgttcc ccaacaccag caaatactga aataccaccg
    12121 tgctcttggg caatgttgtg aatcaattct tggattaaga cagttttacc aactccggca
    12181 ccaccgaaaa gtccaacttt accaccttta aggtaagggg caagaaggtc aataaccttg
    12241 atccctgttt caaggatttc agaagaggta gacaactcat caaaagttgg agctttttta
    12301 tgaattggct gacgctctgc gtcttctgta aaaggagctt ccaagtcaat ggtatctccc
    12361 aaaacgttga agacacgtcc caaagtttct ttacctactg gtacagagat tggacgacct
    12421 gtgtccaata cttccattcc acgagtcaac ccatctgttg attccatggc gatagtacga
    12481 accataccat ctcctaactc caaggctact tcaaggacga tttttgtttt tctttcgtca
    12541 tttttgtaga cgacaagtgc attgttaatc tcaggaagtt tttcccctgc tgcaaacaaa
    12601 acgtctacaa cgggaccgat aacctgagca attttacctg aactcatctc cttctcctat
    12661 tctatataag atactgtcgg ttcctagctc aactaggtcc taagttcatt ttcatacgag
    12721 ctggactaga gcctattcta aggcactagc acctgctacg atttctgtaa tttcttgtgt
    12781 aatcgccgcc tgtctggcac ggttatactg aattgtcaaa tcattgatga ctttcttagc
    12841 attatctgtc gctgtttgca tggctgtcat acccgcagca ttctcagctg tcttggcatc
    12901 tataatggca ccgtaaatca tactttctgc aaactgaggc aacaactgct ccagaatttc
    12961 ttctcggctg gtttccaatt caaaagtcaa gctgtactct tcatccgctt catttggatc
    13021 caagtcaaca atcggaagca tttgttccac acgcatttga ctggttagcg tattgacatg
    13081 gtggttgtag caaacataaa gctcatcaaa gagttcattt tggtacattt caacagtttt
    13141 tgaaataatc ttacgaactt gatcaaagct aggttggtct gccaagccac gtaattcata
    13201 aagtggttga ataccgcgag ccttaaagaa atcagctccc atcccaccga tacagatcat
    13261 ttcaaaacct ttaccgtctg ggtggtattc ttctttcaac tccataacag ctttcaaaat
    13321 agaggaatta taacctccaa ccaaaccgcg gtctgaagtg ataacgatat agcctgtctt
    13381 cttcacagaa cggctaatca acatcggatt agttgaagca ccagctccat taccatgaag
    13441 gatatctgtc aaaagtttac gcactttctg agcgtaaact tggaagttgc gagcagcttc
    13501 ttcagagcga cctagcttag cagccgatac catttgcatg gcattagtga tttgactcgt
    13561 attttttgtt gaggcgattt ttgttttaat atcatttaga gatactgcca tctgacacct
    13621 ctattcttat tggaagctag attgattgag aaactctgta atcgcagcat ccaagactgc
    13681 ttcttctggc aagtcttttg tatcacgaat ggtttccaaa atctctggat gttgagcatc
    13741 aaagaaggca tggaactctt cctcgaaacg aacaatatca tctactggaa cagtatccaa
    13801 gaaaccatgt atcaaagcat aaagaatggt tacttgtttc tcaacaggta atggtttgtg
    13861 aacaggttgt ttcaagacct caacggtacg acgtccacgg ttcaacttag cctgtgttgc
    13921 tgcgtccaag tcagaaccaa acttagtaaa ggcttccaac tcacggtatg aagcaaggtc
    13981 gatacgaagt gtaccagcaa ccttcttcat ggctttgatt tgtgcagaac cacctacacg
    14041 agatacagat gaacccgcat cgatggctgg acgaatacct gcattgaaga ggccatcgcc
    14101 aaggaagatt tgtccatcag tgatagaaat cacgttggtt gcgatatagg ctgagatatc
    14161 tcctgcttgt gtctcgataa atggtagggc tgtaattgat ccaccaccaa gttcatcaga
    14221 aactttagct gagcgctcaa gcaaacggct gtggagatag aaaacatccc ctgggaaggc
    14281 ttcacgacct ggaggacgac gaagcaagag cgacagttca cgataagcta ccgcttgttt
    14341 tgatagatca tcgtatacaa tcaaaacatg cttaccttga tacataaatt cttccgccat
    14401 agcgacccca gtataaggag ctaggaagag caatggagat ggttgtgaag cagaggctgt
    14461 cacaacgatt gtgtagtcca aggcaccgta ctgacgaagt gtttctactt gcgtacgaac
    14521 tgttgattct ttttgtccaa tcgcgacgta gatacagatc atatcttgat ctttttggtt
    14581 caagattgta tcaatcgcaa tggttgtttt ccctgtctga cggtcaccga taatcaactc
    14641 acgttgacca cgaccaatcg gtacaagggc gtcaatagct ttcaaaccag tttgcaatgg
    14701 ttctgaaaca gacttacgtt gcataacacc aggagctggt gcttctactg gacgagtttt
    14761 atcagtgtgg atttctccaa gaccgtcaac tggacgacca agcggatcca caacacgacc
    14821 aatcagactt tcacctacag ggacttccat gattttccct gtacggcgga ttgtatcgcc
    14881 ttcacggata tctgtaaagt cacctaggat gataatacca acgtctgttg actccaagtt
    14941 ttgagccata ccataagagc cgttttcaaa attcaacaac tctccactca tgacattttc
    15001 aaggccgtga gcacgcgcga taccgtcccc gatataggtt acaacacctg tttcagtcac
    15061 atcaaaattg ggtttgaaat tttcaatttg ttgcttaatt aaagcgctga tttcttgtgc
    15121 gttaattgcc aaaagaacac cactttctat ttcaaatttt ctttaacaac tttaagttgt
    15181 tgtttaatac tcacatcaat tgtcttgtga ttggcaaaaa tgacaaaacc accaatgaga
    15241 ctttcatcga tttgttcttt tacactcctt actttcagag acattttttt ctcaatcaaa
    15301 gggagcaaac gagtcttctg ttcatcagtt agaggatgag cagacgtaat cgtcacttca
    15361 aatcgatttg tttctttttc aagtcggttc aagcaatcta caagcacatc ataaaaaaga
    15421 tttgctctgt gattgtaggc cagaacctgg ataaagtttt gtaataaagg cgacacagaa
    15481 tcttggaaaa aagcaattgt tttttcctta tccgactcgt ctactgccac ttgttttaaa
    15541 aaagaaggca gacctgtttt ttcaacaact tgcttgattt gagtcaagtc tgaaaagata
    15601 cggtcttctt ctcctttttc aagtaccaat tggacaaaag gcatgctgta tttttcaatt
    15661 acctttactg ttttcttgtc cattaagctt ctcctagctg atcgatatac tgatcaatga
    15721 gtgctttatg ggcatgactg tcaaggtttt gtgagatgat tttaccagct aagctgatgg
    15781 tcagatctgc gacctcaccc ttaacactct gtaaagcttc tactttattt tgagcaattt
    15841 cttgattggc tttttctttt aagtgtcctg cttctagttt agcatctgct aagatattag
    15901 ccttactttg ctcagctgtt tcctttgcat tttcaatgat tgtcttagct tctttacggc
    15961 taccagccaa ttcatcttcg cgtttttgag ccaatacttc tgctttttga cgggcttctt
    16021 cagctctgtc aatatctgaa gcaatttttt cagctctttc ttcgaaaatg cctgtaatat
    16081 tagaccatgc aaatttttta atcaagacta gcaaaagaat aaaagagcca gtgattaaaa
    16141 taaaattacc aattaattca cctactgtta cgtgcatcag ttactccttt ctattcctct
    16201 tcaatattaa tcttattccc taaatacaca gatgtcaaaa gagtaaaaac ataagcttgg
    16261 atgcaggaaa taaagacaga aaatgcagtc caagccaaat tagctccaaa ggctactgga
    16321 taccaataaa tagcttggtg ggaaagaaga agtaacaaac tcgtcatgac ctctcctgca
    16381 aagatattcc caaaaatccg caaagccaaa gataagaagt ttgtaaattc ttccaagata
    16441 ttcatcggta tgacaaaaac aggactcata aaagatttta tacttttttt aaatccacga
    16501 cgacgaacgc tttctatatg tgtcaacaaa atgacaagaa aagataaggt taagtcatac
    16561 tgtaaattag cggttggcga actccaccag ttagtcccat cgatcgtttg aagctttgtc
    16621 attaagccaa ggttattggc aatcaccatg aaaaggaata aacaaaggaa aaagagtgaa
    16681 taatctttca tgtagcgcga accaatgtta ggttctgtaa atccaataac aaagtcatag
    16741 acatactcaa gtacattttg ctttcctttg ggtttcaagg tcatattgcg gcttgcccaa
    16801 taaataaaga caaaaataac tcccacaatc aacaaagtca tggctaacat agtcagattg
    16861 aagataacag gaccaataga gatgattgga ttaatacttt cttccatcta aaatcctccc
    16921 ttttcttctc gttccatgta tttatttgat aataaatgag aagacaagag ttacaaagaa
    16981 agttccttca ataaaggcaa cacctaaaaa catcaaacta cgaaactcag aaagcatatc
    17041 tggttggcgt gctactgatt taaacagtcc attcatcaat aaaccttcac cgacagatac
    17101 gcccatacag gcaatacata agcctaaaaa tgttaaattc ataacaaatt ctcctttaaa
    17161 ataaaattta cttacttagt gtagtcctaa aatttaaatt tgtcaacttt taaccgctat
    17221 tggaagcgtt taataaaaat tatttccatt ttgctaaatt tcaagttcaa gttagccatc
    17281 ca
//
LOCUS       DAVAZV010000049        16132 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVAZV010000049 DAVAZV010000000
VERSION     DAVAZV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16132
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.049"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            145..6831
                     /locus_tag="VQT46_001610"
     CDS             145..6831
                     /locus_tag="VQT46_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET2371610.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTVEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQTSNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLATVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGFKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVARVRTLIGKEPKMPKTVGFVYSDGSREKLPVTWSQ
                     VDVSQAGVVTVKGTANGREVEAHVEVLAIAKELPTVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEITEVDKAKLSVAGSRIQMTGQLAGETIHATLVVEEGNAAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEDTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRTNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQIRIQVDGKDLANFNPD
                     LTDYYLESVDGKVPAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQAKLRFFA
                     DSGTDAPTKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IQLTKEKPVSAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGKERIFT
                     AINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSEASQTN
                     KAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(7079..7935)
                     /locus_tag="VQT46_001611"
                     /pseudo
     CDS             complement(7079..7935)
                     /locus_tag="VQT46_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(8146..8505)
                     /locus_tag="VQT46_001612"
     CDS             complement(8146..8505)
                     /locus_tag="VQT46_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET2371611.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            8597..9553
                     /locus_tag="VQT46_001613"
                     /pseudo
     CDS             8597..9553
                     /locus_tag="VQT46_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            9537..10094
                     /locus_tag="VQT46_001614"
     CDS             9537..10094
                     /locus_tag="VQT46_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET2371612.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            10087..10341
                     /locus_tag="VQT46_001615"
     CDS             10087..10341
                     /locus_tag="VQT46_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371613.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            10353..12407
                     /locus_tag="VQT46_001616"
     CDS             10353..12407
                     /locus_tag="VQT46_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET2371614.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            12586..13446
                     /locus_tag="VQT46_001617"
     CDS             12586..13446
                     /locus_tag="VQT46_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET2371615.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQT46_001618"
     CDS             13657..14367
                     /gene="ccdA2"
                     /locus_tag="VQT46_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2371616.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            14387..14953
                     /locus_tag="VQT46_001619"
     CDS             14387..14953
                     /locus_tag="VQT46_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET2371617.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            14964..16076
                     /gene="msrB"
                     /locus_tag="VQT46_001620"
     CDS             14964..16076
                     /gene="msrB"
                     /locus_tag="VQT46_001620"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET2371618.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         4901 a         3052 c         3565 g         4614 t
ORIGIN      
        1 catatctacg gcaaggcgac actgacgaag tttgaattgg attttcgcag agtgtaaatt
       61 gttgaaacta ggttgtcata ccatgtatac cacttgggct ttggtagtag ctaactgcac
      121 taaatataat ataaggaggg ttttatgggg aaaggccatt ggaatcggaa aagagtttat
      181 agcattcgta agtttgctgt gggagcttgc tcagtaatga ttgggacttg tgcagttcta
      241 ttaggaggaa atatagctgg agaatctgta gtttatgcgg atgaaacact tattactcat
      301 actgttgaga aacctaaaga ggaaaaaatg atagtagaag aaaaggctga taaagctttg
      361 gaaactaaaa atgtagttga aaggacagaa caaagtgaac ctagttcaac tgaggctatt
      421 gcatctgaga agaaagaaga tgaagccgta actccaaaag aggaaaaagt gtctgctaaa
      481 ccggaagaaa aagctccaag gatagaatca caaacttcaa atcaagaaaa accgctcaag
      541 gaagatgcta aagctgtaac aaatgaagaa gtgaatcaaa tgattgaaga caggaaagtg
      601 gattttaatc aaaattggta ttttaaactc aatgcaaatt ctaaggaagc cattaaacct
      661 gatgtagacg tatctacgtg gaaaaaatta gatttaccgt atgactggag tatctttaac
      721 gatttcgatc atgaatctcc tgcacaaaat gaaggtggac agctcaacgg tggggaagct
      781 tggtatcgca agactttcaa actagatgaa aaagacctca agaaaaatgt tcgccttact
      841 tttgatggcg tctacatgga ttctcaagtt tatgtcaatg gtcagttagt ggggcattat
      901 ccaaatggtt ataaccagtt ctcatatgat atcaccaaat accttcacaa agatggtcgt
      961 gagaatgtga ttgctgtcca tgcagtcaac aaacagccaa gtagccgttg gtattcagga
     1021 agtggtatct atcgtgatgt gactttacaa gtgacagata aggtgcatgt tgagaaaaat
     1081 gggacaacta ttttaacacc aaaacttgaa gaacaacaac atggcaaggt tgaaactcat
     1141 gtgaccagca aaatcgtcaa tacggacgac aaagaccatg aacttgtagc cgaatatcaa
     1201 atcgttgaac gaggtggtca tgctgtaaca ggcttagttc gtacagcgag tcgtacctta
     1261 aaagcacatg aatcaacaag cctagatgcg attttagaag ttgaaagacc aaaactctgg
     1321 accgttttaa atgacaaacc tgccttgtac gaattgatta cgcgtgttta ccgtgacggt
     1381 caattggttg atgctaagaa ggatttgttt ggttaccgtt actatcactg gactccaaat
     1441 gaaggtttct ctttgaatgg tgaacgtatt aaattccatg gagtatcctt gcaccacgac
     1501 catggggcgc ttggagcaga agaaaactat aaagcagaat atcgccgtct caaacaaatg
     1561 aaggagatgg gagttaactc catccgtaca acccacaacc ctgctagtga gcaaaccttg
     1621 caaatcgcag cagaactagg tttactcgtt caggaagagg cctttgatac ttggtatggt
     1681 ggcaagaaac cttatgacta tggacgtttc tttgaaaaag atgccactca cccagaagct
     1741 cgaaaaggtg aaaaatggtc tgattttgac ctacgtacca tggtcgaaag aggcaaaaac
     1801 aaccctgcta tcttcatgtg gtcaattggt aatgaaatag gtgaagctaa tggtgatgcc
     1861 cactctttag caactgttaa acgtttggtc aaggttatca aggatgttga taagactcgc
     1921 tatgttacca tgggagcaga taaattccgt ttcggtaatg gtagcggagg gcatgagaaa
     1981 attgctgatg aactcgatgc tgttggattt aactattctg aagataatta caaagccctt
     2041 agagctaagc atccaaaatg gttgatttac ggttcagaaa catcttcagc tacccgtaca
     2101 cgtggaagtt actatcgccc tgaacgtgaa ttgaaacata gcaatggacc tgagcgtaat
     2161 tatgaacagt ctgactatgg aaatgatcgt gtgggttggg ggaaaacagc aaccgcttca
     2221 tggacttttg accgtgacaa cgctggctat gctggacagt ttatctggac aggtacggac
     2281 tatattggtg aacctacacc atggcacaac caaaatcaaa ctcctgttaa gagctcttac
     2341 tttggtatcg tagatacagc cggcattcca aaacatgact tctatctcta ccaaagccaa
     2401 tgggtttctg ttaagaagaa accgatggta caccttcttc ctcactggaa ctgggaaaac
     2461 aaagaattag catccaaagt agctgactca gaaggtaaga ttccagttcg tgcttattcg
     2521 aatgcttcta gtgtagaatt attcttgaat ggaaaatctc ttggttttaa gactttcaat
     2581 aaaaaacaaa ccagcgatgg gcggacttac caagaaggtg caaatgctaa tgaactttat
     2641 cttgaatgga aagttgccta tcaaccgggt accttggaag caattgctcg tgatgaatct
     2701 ggcaaggaaa ttgctcgaga taagattacg actgctggta agccagcggc agttcgtctt
     2761 attaaggaag accatgcgat tgcagcagat ggaaaagact tgacttacat ctactatgaa
     2821 attgttgaca gccaggggaa tgtggttcca actgctaata atctggttcg cttccaattg
     2881 catggccaag gtcaactggt cggtgtagat aacggagaac aagccagccg tgaacgctat
     2941 aaggcgcaag cagatggttc ttggattcgt aaagcattta atggtaaagg tgttgccatt
     3001 gtcaaatcaa ctgaacaagc agggaaattc accctgactg cccactctga tctcttgaaa
     3061 tcgaaccaag tcactgtctt tactggtaaa aaagaaggac aagagaagac tgttttgggg
     3121 acagaagtag caagagttcg tacattaatt ggtaaagaac caaaaatgcc gaaaacagta
     3181 ggttttgtat acagcgatgg tagtcgtgaa aaacttccag taacttggtc tcaagtcgat
     3241 gttagtcaag caggagttgt gactgttaaa ggtacagcaa atggacgtga ggtagaggct
     3301 catgtcgagg ttctagcaat tgcgaaagaa ttaccaacag ttaaacgtat tgctccaaat
     3361 actgacttga attctgtaga caaatctgtt tcttatgttt tgactgatgg aagtgtacaa
     3421 gagtacgaag tagatagctg ggagattacg gaagtagata aagccaaact ttcagtagct
     3481 ggatcacgta ttcaaatgac tggtcagtta gctggagaaa ctattcatgc aacccttgtg
     3541 gtagaagaag gaaatgctgc agcacctgta gtgccaactg ttactgttgg aggtgaggca
     3601 gtaacaggtc ttactagtcg acaaccaatg caatatcgta ctctatctta tggtgcccaa
     3661 ctgccagaag tcacagcaag tgctgaaaat gctgatgtga cagttcttca agcaagcgca
     3721 gcaaacggca tgcgtgcgag catctttatt cagcctaaag atggtggtcc tcttcaaacc
     3781 tatgcaattc aattcctaga agaagcacca aaaattgctc acttgagttt gcaagtggaa
     3841 aaagctgaca gtctcaaaga agaccaaact gtcaaattgt cggttcgagc tcactatcaa
     3901 gatggaacgc aagctgtatt accagctgac aaagtaacct tctctacaag tggtgaaggg
     3961 gaagtcgcaa ttcgtaaagg aatgcttgag ttgcataagc caggagcagt cactctcaaa
     4021 gcggaatatg agggagctaa aggccaagtt gaactcacta tccaagccaa tactgagaag
     4081 aagattgcgc aatctatccg tcctgtaaat gtagtcacag atttgcatca aaaacctact
     4141 cttccaacaa cagtaacggt tgagtatgac aaaggtttcc ctaaagctca caaagtcact
     4201 tggcaagcta ttccgaaaga aaaactagac tcctatcaaa catttgaagt actaggtaaa
     4261 gttgaaggaa ttgaccttga agcgcgtgca aaagtctctg tagaaggtat cgtttcagtt
     4321 gaagaagtca gtgtgacaac tccaatcgca gaagcaccac aattaccaga aagcgttcgg
     4381 acatatgatt caaatggtca cgtttcatca gctaaggttg catgggatgc gattcgtata
     4441 gagcaatacg ctaaggaagg tgtctttaca gttaatggtc gcttagaaga tactcaatta
     4501 acaactaaac ttcatgttcg cgtatctgct caaactgagc aaggtgcaaa catttctgac
     4561 caatggaccg gttcagaatt gccacttgcc tttgcttcag attcaaatcc aagcgaccca
     4621 gtttcaaatg ttaatgacaa gctcatttcc tacaataacc aaccagccaa tcgttggaca
     4681 aactggaatc gtactaatcc agaagcttca gtcggtgttc tgtttggaga ttcaggtatc
     4741 ttgagcaaac gctccgttga taatctaagt gtcggattcc acgaagacca tggagttggt
     4801 gcaccgaagt cttatgtgat tgagtattat gttggtaaga ctgtcccaac agctcctaaa
     4861 aaccctagtt ttgttggtaa tgaggaccat gtctttaatg attctgccaa ctggaaacca
     4921 gttactaatc taaaagcccc tgctcaactc aaggctggag aaatgaacca ctttagcttt
     4981 gataaagttg aaacctatgc tgttcgtatt cgcatggtta aagcagataa caagcgtgga
     5041 acgtctatca cagaggtaca aatctttgcg aaacaagttg cggcagccaa acaaggacaa
     5101 ataagaatcc aagttgacgg caaagactta gcaaacttca accctgattt gacagactac
     5161 taccttgagt ctgtagatgg aaaagttccg gcagtcacag caagtgttag caacaatggt
     5221 ctcgctaccg tcgttccaag cgttcgtgaa ggtgagccag ttcgtgtcat cgcgaaagct
     5281 gaaaatggcg acatcttagg agaataccgt ctgcacttca ctaaggataa gaacttactt
     5341 tctcataaac cagttgctgc ggttaaacaa gctcgcttgc tacaagtagg tcaagcactt
     5401 gaattgccga ctaaggttcc agtttacttc acaggtaaag acggctacga aacaaaagac
     5461 ctgacagttg aatgggaaga agttccagca gaaaatctga caaaagcagg tcaatttacc
     5521 gttcgaggcc atgtccttgg tagtgatctt gttgctgagg tcactgtacg agtgacagac
     5581 aaactaggcg aagctctttc agataaccct aactatgatg aaaacagtaa ccaggccttt
     5641 gcttcagcaa ccaatgatat tgacaaaaac tctcatgacc gcgttgacta tctcaatgac
     5701 ggagatcatt cagaaaatcg tcgttggaca aactggtctc caacaccatc ttctaatcca
     5761 gaagtatcag cgggtgtgat cttccgtgaa aatggtaaga ttgtagaacg gactgttgcc
     5821 caagccaaac ttcgtttctt tgcagatagt ggtacggatg caccaactaa actcgtttta
     5881 gaacgctatg tcggtccaga gtttgaagtg ccaacctact attcaaacta ccaagcctac
     5941 gacgcagacc atccattcaa caatccagaa aattgggaag ctgtgcctta tcgtgcggat
     6001 aaagacatcg cagctggtga tgaaatcaac gtaacattta aagctgtcaa agccaaagct
     6061 atgagatggc gtatggagcg taaagctgac aagagcggtg ttgcgatgat tgagatgacc
     6121 ttccttgcac cgagtgaatt gcctcaagaa agtacgcaat cgaagattct tgtagatgga
     6181 aaagaacttg ctgatttcgc tgaaaatcgt caagactatc aaattaccta taaaggtcaa
     6241 cggccaaaag tctcagttga agaaaacaat caagtagctt caactgtggt agatagtgga
     6301 gaagatagcc ttccagtact tgttcgcctc gtttcagaaa gtggaaaaca agtcaaggaa
     6361 taccgtatcc agttgactaa ggaaaaacca gtttctgctg tacaagaaga tcttccaaaa
     6421 ctcgaatttg ttgaaaaaga tttggcctac aagacagttg agaaaaaaga ttcaacactg
     6481 tatctaggtg aaactcgtgt agaacaagaa ggaaaaactg gtaaagaacg tatctttaca
     6541 gcgattaatc ctgatggaag taaggaagaa aaactccgtg aagtggtaga agctccgaca
     6601 gaccgcatag tcttggttgg aaccaaacca gtagctcaag aagctaaaaa accacaagtg
     6661 tcagaaaaag cagatacaaa accaattgat tcaagtgaag ctagtcaaac taataaagcc
     6721 cagttaccaa atacaggtag tgcggcaagc caagcagcag tagcagcagg tttagctctt
     6781 ctaggtttga gtgcaggatt agtagttact aaaggtaaaa aagaagacta gaaattttga
     6841 taccttcttt atcattaaag accaaagaaa aactcttgtc ctaaatagaa gataaagagt
     6901 ctggaacaaa atagttctca accacaaaaa agctagatat ttccaattgc ggaactctag
     6961 ctttttaatt ttgagtcgtt ctcttattgt atagtagatt gaaactagaa tagtacactt
     7021 ctacttctaa aacattgtta gaaatcaatt tgactgtcct tatcgatttg tcctgttctt
     7081 atttcatttc actatgtttt aggaggttat tggccataag taccaatccc atgtcaattc
     7141 tcacttgacg cttccctctc agattacatc tcttgtaacc caaacaagcc tttatctgcc
     7201 caaagacagg ttccacatca atcttgcgtt gagcgaaaat ctgtctacct tggggagata
     7261 aaagcgcctg acattcttta gctttcaagt tttgatagcg ttcgttcata tacagtccct
     7321 tttgagggac tgattcaggt tcatcagcgt agtaaacctt gatttcctgt tgaaagtctg
     7381 tctgtgtttt ctggtacttg atatggtgaa aacgatagca ccagccatca ggatgtgtgt
     7441 agctatcctc cttgtcatta tagtgccaat tcgctaagtt tttagctgac tgtttatacc
     7501 ctctcttttg ttccttatca aacatggcat atttaatcag aaggggagtg atttcttctt
     7561 gaaaatagac ctgtatctgt tcttgaagtt tggcggagaa tttctctgtc gttttcttcc
     7621 acacaaaact atacttgttg gcattggctt caatcttagt tccgtcaata aacaaacaat
     7681 ctaaggtcac taactcttcc atttttcaat ttttcgacca gagaaaatcc cttgtgaata
     7741 ggcaaataga agagtagata caagcatttt agggtgataa gacgggcgat caaaggcatg
     7801 atagaaggcg tggaagtgac aatcctccaa ggtattcacc actttttcaa tagtaaaaac
     7861 gagatgatct tgtggcaaga aggaactgat ttctagtggt aaagttgttt gatttgtgtt
     7921 atagtgaata tgcatgggat agcctttcta aatggtttat taagcaattc tattttacca
     7981 agactatcgc aaccatgcaa aaaagcaacg gcaaatccgt tgcctttttt ggagataaga
     8041 gactattgtc ccagactctt ttctttgtat aaaattgtat agtgttattg tctatactat
     8101 tttgtagaga aagcaaaaat ccctagaaaa tgcttaggga ttcgactatt tcattaagaa
     8161 caattcaaca atcatttcta tatacatgat aagggttaat aagaatcctg cacgccagaa
     8221 gaatttgata aatttaggat agtaaaagct gcgttttttc aaaaggaaga aaaagacgag
     8281 aataatggct aggatcgaga gggctagccc cagtctaggg aggaaattat gggtaaaggt
     8341 tttagctgta atcaagtaat actcaaatac caagactgga aaagccaaat ccgcaaagtt
     8401 tcgtcctagt ttttttaatc taaaaagttt ggttaggata atgcagacga ctaaggtcag
     8461 tatcaataat aaaatagatg ctaatttcat taaaatcata cccatattgt atcataaaaa
     8521 aaggctaatg gaaacgagaa acagaggaat ttataggaaa gtcaggcttt tgagattgtg
     8581 ggtgattttt gttataatga aagttataaa atcttataat accttgaatg attattatcg
     8641 aaaactcttt ggagaaaaga cttttaaagt ccctattgat gcgggatttg actgtcccaa
     8701 tcgtgatgga actgtggctc atggaggctg tactttttgt acggtttccg gttctggaga
     8761 tgccattgtg gcaccagatg cgcctatccg tgagcaattt tataaggaaa ttgactttat
     8821 tcatcgtaag tggccagatg ttcagaagta tctggtttat tttcaaaatt ttaccaacac
     8881 ccatgaaaag gtggaagtta ttcgagagcg ttatgaacag gctatcaatg agccaggtgt
     8941 ggtaggaatc aatattggaa cgcgcccaga ctgtttacca gacgaaacca tcgaatattt
     9001 ggctgagtta tcggagtgca tgcatgtgac ggttgaattg ggcttgcaaa ctacttatga
     9061 agcaacctct gacctgatta accgtgcgca ttcttatgaa ttgtaggtgg aaacggtcaa
     9121 gcgtttgaga aagtatccaa aaattgagat tgtttcccat ttgatcaatg gtttgcctgg
     9181 tgaaacccat gagatgatgg ttgaaaatgt ccgccgttgt gtcacggata acgatattca
     9241 agggattaaa ctgcatttgc tccatcttat gacaaatact cgtatgcaac gagattacca
     9301 tgaggggcgt ttacaattga tgagtcagga cgaatatgtc agggtcatct gtgaccaact
     9361 ggaaattatt cccaaacata tcgtcatcca tcgaattaca ggagatgcgc ctagggatat
     9421 gctgcttggg cctatgtgga gcctcaataa atgggaagct ctcaacagca ttgagatgga
     9481 gatgcgacgt cgtggaagtg ttcaaggatg caaggctgta aaacaggagt ttgaaaatga
     9541 aaagaccact tgagatggca catgattttt tggctgaggt cgtgacaaaa gaggatgtcg
     9601 tagtggatgc gactatggga aatggtcatg acacgctttt tttagccaag ctagccaagc
     9661 aagtctatgc ctttgatatt cagaagcaag ccttggaaaa gacccaagag cgtttgcatc
     9721 aggctgactt gacaaatgcc cagttaatct tgcaaggcca tgagacactg gaccagtttg
     9781 tgataaaagc taaggcaggg atttttaatc tgggctattt gccgtcagct gataagtctg
     9841 tcatcacccg accgcagaca acgattgagg cattagaaaa gctatgtggc ttacttgtca
     9901 aaggtggacg aattgctatt atgatttact atggtcatga aggaggcgat ctcgagagag
     9961 atgctgtctt ggattttgtg atccagttga accaacaaga gtacacagct gccatttacc
    10021 gaactttaaa ccaagtcaac aacccgccgt ttttagtgat gattgaaaaa ttagagagat
    10081 acagacatgg ataaacaata cctacacgaa aagctggatg ccatgcgcca gaattttgtt
    10141 gaatcaaccc accacgaacg atcggtgggc gtgctagacc aagcgcatat gagcaaaaaa
    10201 atgcttaaaa tcaagaaaaa attagttgct cttgaaatgg aacggtgcca gagaaaaatt
    10261 gagcacaaag actgttccaa gattgaccaa aaaatcaaag agcagaagga gatatttgaa
    10321 tcctgttgta aaaaagatta aggaggacgt gcgtggaatt actgatttac ctcatcctat
    10381 ttttactggt tttgattgtc tcaagtacaa ccaataagct cctgcccttt ttgcctctcc
    10441 ctttggtgca gattcttttg ggaattgtga ttggtctctt tttacccaat actgactttc
    10501 accttaatac ggagttgttt ttggcactgg ttatcggacc cttgcttttc cgagaggctg
    10561 aagaagcaga tgttacggct attttaaaac actggcgaat cattgtttat ctcatatttc
    10621 cagtgatttt tatctcgacc ttgagtttgg gtggcttggc ccatcttctt tggttcagcc
    10681 ttcccttggc agcttgcttg gctgttgggg cagcccttgg tcctacggac ttggtggcct
    10741 ttgcctctct ttcggagcgt tttagctttc ctaagcgcgt gtccaatatt cttaagggcg
    10801 aaggactctt gaatgatgct tctggtttgg tggcttttca ggtagctttg acagcttgga
    10861 caactggagc tttttctctg gggcaagcta gcagttcgct catcttttca atcctaggcg
    10921 gttttttaat tggattttta acggccatga ccaaccgctt cctccatacc ttcttgctaa
    10981 gtgtgcgcgc aacggatatt gccagtgaac ttttattaga attgagtttg cctctagtga
    11041 ccttctttct ggcagaagaa gttcatgttt caggtattat tgccgtcgta gttgctggaa
    11101 ttttaaaggc aagtcgcttc aagaaaatca cgctcctcga agcccaagtg gatacggtga
    11161 ccgagacggt ctggcataca gtgaccttta tgctcaacgg ttctgtcttt gtgattttag
    11221 ggatggagtt ggaaatgata gcagaaccta tcttgaccaa tccaatctat aatcctctac
    11281 ttttattgct atctctcatc gcccttacct ttgtcctctt tgtcattcgt tttattatga
    11341 tctatggcta ttatgcctat agaacccgac gcctcaagaa aaagctaaat aagtatatga
    11401 aggacatgtt tctcttgacc ttttcaggtg ttaagggaac ggtgtcgatt gctacgattc
    11461 tcttgatacc aagtaatcta gaacaggagt atcctctttt gcttttcctt gttgcaggtg
    11521 tgacgcttgt cagcttttta acaggtctct tggtcttgcc tcatctttct gatgaagagg
    11581 aagaaagcaa ggattatctc atgcatatcg ccattttgaa tgaagtaacg ctagagttgg
    11641 aaaaagagtt ggaagacacc agaaataaac ttcccctcta tgcggctatt gacaattatc
    11701 atggacgtat tgaaaatctc attttaagcc aagaaaacca ggatgatcaa gaagattggg
    11761 ctgctttgaa actcttgatt cttagtattg aaagtgatgg tttggaacag gcctatgaag
    11821 aggggaacat tagcaatcgt gcttaccgag tttaccaacg ttatctgaaa aatatagaac
    11881 aaggaatcaa tcgtaaactt gcctcaagac tgacctatta ttttcttgtt tccttgagga
    11941 ttttacgttt tctccttcat gaagttttta ctcttggaaa gaccttccgt agctggaagg
    12001 acaaggagca aagccgtctc cgtgctcttg attatgacca aattgcagag ctctatcttg
    12061 ccaatacaga gatgattatt gaaagtttgg aaaacctgaa gggagtctac agacgctctt
    12121 tgattagttt tatgcaggag tctcgtcttc gagaaacagc tattatcagc agtggtgcct
    12181 ttgtcgaacg ggttatcaat cgtgtcaaac ccaacaatat cgatgaaatg ctgagaggct
    12241 attatctgga gcgcaagttg attttcgaat acgaagaaaa acgattgatt acgactaagt
    12301 atgccaagaa attacgacaa aatgtaaata acttagagaa ctattccttg aaggaagctg
    12361 ccaataccct gccgtatgat atggtggaat tggtaagaag aaattagtta atactcttcg
    12421 aaaatctctt caaaccacgt cagcgtcgcc ttggattata tatgtgactg acttcgtcag
    12481 tttcatctac aacctcaaag cagggctttg agcaacctgc ggctagcttc ctagtttgct
    12541 ctttgatttt cattgagtat aagattataa atgaaggagt atgacatgaa aaagtggtgg
    12601 aaagagctga tagacaagcc tttattaaaa gcttttttgc attattatca agcatcagat
    12661 agtgagttga ccagtgtcgc agtagcctac tattggttga tttcgatttt ccccctgctt
    12721 ttggtggtgg tcaatatcct cccctatttt cagattcctg tgggagaatt tctgtgcttt
    12781 atgaaagacg ttctgccccc aagcctctat gaaggtgtgg aaaaaatagc cagagaagtt
    12841 ttgacgcaac cttcaacagg tttattgagt ttttctgttt tatcggcgtt atggagtttt
    12901 tcaaaatcta tgaatttctt gcaaaaagct tttaacaagg cttatggcgt cgaaaagagt
    12961 cgtggactta tttcccatca gatgctaagt ctcctagtca gttttggctt gcagctcctc
    13021 tttgcgtttg ccttgttttt gatcttattt ggtcagatga ttttggcttt acttgctcat
    13081 tattggacaa aagatggcat tatctatcag gctttacaag ggttggcagg tcctctgatt
    13141 tacgccctcc tctttgctat cttggtcatg ctttattatt ttcttcccaa tctatctaac
    13201 aggaaaatta gctataccct accaggcagt gcctttgttc tcttagtgat tttaggttta
    13261 ctaactctgt tctctagtta tctcaattac tatgtccatc atttggtgga tgtccgaatt
    13321 ttaggttccg ttcttcttgt tgttatgatg ttttggttta tcttgattgc taaaattgtt
    13381 atcctaggcg cggttatcaa tgccagtatg cagagtttga aagatccggt ctttaaaaaa
    13441 gactaactat ttatccatta caaaagcgca tagtatcaaa actttataga accttgatac
    13501 tatgcgcttt tgtgctttga cagttttttg tatagttttt gtccaagatt tctaaatcat
    13561 ctgattaaat tcctattttc ccctatcatt gtccctgttt tttcgaaaat ggaaggagta
    13621 taataaatct atcaataaaa tgataggagg aactttatgg gtcatatttt cttttttcta
    13681 agtgtctttt tggcagggat tctatccttc ttttctcctt gtatcttacc tttgttaccg
    13741 gtctatacag gagtgttact agatgataag gatggtgctc aggcttctag cggcaaattt
    13801 tcaatctcag ttactagttt attacgaact ctggccttta tagcaggaat ttcctttata
    13861 tttattttgt tgggctatgg agctggtttt ttaggcgatt tgctttatgc ttcttggttc
    13921 caatatctta ctggggcaat tattatcctt cttggtttgc accaaatgga gattctacac
    13981 tttaaggggc tttataagga aaagaggcta caactgcaag gacaggggca aaatggtaag
    14041 ggctatagtc aggcattttt attgggcttg acctttagtt ttgcttggac gccttgcgtg
    14101 gggccggttc tggggtctgt tttggccttg gcggcttcag gtggttcagg agcttggcag
    14161 ggagctggtc tcatgttggt gtatacgctg ggcttggcgc taccattctt gcttctagct
    14221 ctgacctcta gttatgtttt gaaacatttc cgaaaacttc atccctatct cggaatcctc
    14281 aaaaaagtgg gtggttttct cattattgtg atgggactct tggttctgtt tggaaatgct
    14341 tcaattttaa gtcaattatt tgaataaaat ggaaaggaat atcaatatga aaaaatggca
    14401 aacatgtgtt cttggagcag gttcgctcct ttgtttgacg gcttgttcag gcaagtccgt
    14461 gactagtgaa caccaaacga aagatgaaat gaagacggag cagacagcta gtaaaacaag
    14521 cgcagctaaa gggaaagagg tggctgattt tgaattgatg ggagtagatg gcaagaccta
    14581 ccgtttatct gattacaagg gcaagaaagt ctatctcaaa ttctgggctt cttggtgttc
    14641 catctgtctg gctagtcttc cagatacgga tgagattgct aaagaagctg gtgatgacta
    14701 tgtggtcttg acagtagtgt caccaggaca taagggagag caatctgaag cggactttaa
    14761 gaattggtat aagggattgg attataaaaa tctcccagtc ctagttgacc catcaggcaa
    14821 acttttggaa acttatggtg tccgttctta cccaacccaa gcctttatag acaaagaagg
    14881 caagctggtc aaaacacatc caggattcat ggaaaaagat gcaattttgc aaactttgaa
    14941 ggaattagcc taggaggtgt cttatgaatg ataagttaaa aatcttcttg ttgctaggag
    15001 tattttttct agccataacc ggtttctatg ttctattgat acgaaatgca gggcagacag
    15061 atgcctcgca aattgaaaag gcggcagtta gccaaggagg aaaagcagtg aaaaaaacag
    15121 aaattagtaa agacgcagac ttgcacgaaa tttatctagc tggaggttgt ttctggggag
    15181 tggaggaata tttctcacgc gttcccgggg tgacggatgc cgtttcaggc tatgcaaatg
    15241 gtagaggaga aacaaccaag tacgaattga ttaaccaaac aggtcatgca gaaaccgtcc
    15301 atgtcaccta tgatgccaag caaatttctc tcaaggaaat cctgcttcac tatttccgca
    15361 ttatcaatcc aaccagcaaa aataaacaag gaaatgatgt ggggacccag taccgtactg
    15421 gtgtttatta cacagatgac aaggatttgg aagtgattaa ccaagtcttt gatgaggtgg
    15481 ctaagaaata cgatcaacct ctagcagttg aaaaggaaaa cttgaagaat tttgtggtgg
    15541 ctgaggatta ccatcaagac tatctcaaga aaaatccaaa tggctactgc catatcaatg
    15601 ttaatcaggc ggcctatcct gtcattgatg ccagcaaata tccaaaacca agtgatgagg
    15661 aattgaaaaa gaccctgtca cctgaggagt atgcagttac ccaggaaaat caaacagaac
    15721 gagctttctc aaaccgttac tgggataaat ttgaatccgg tatctatgtg gatatagcaa
    15781 ctggggaacc tctcttttca tcaaaagaca aatttgagtc tggttgtggc tggcctagtt
    15841 ttacccaacc catcagtcca gatgttgtca cctacaagga agataagtcc tacaatatga
    15901 cgcgtatgga agtgcggagc cgagtaggag attctcacct tgggcatgtc tttacggatg
    15961 gtccacagga caagggcggc ttacgttact gtatcaatag cctctctatc cgctttattc
    16021 ccaaagacca aatggaagaa aaaggctacg cttatttact agattatgtt gattaatact
    16081 cttcgaaaat ctcttcaaac cacgtcagcg tcgccttacc gtatgtaggg tt
//
LOCUS       DAVAZV010000050        16071 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVAZV010000050 DAVAZV010000000
VERSION     DAVAZV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16071
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.050"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            63..527
                     /locus_tag="VQT46_001621"
     CDS             63..527
                     /locus_tag="VQT46_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET2371619.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            685..1110
                     /gene="lacA"
                     /locus_tag="VQT46_001622"
     CDS             685..1110
                     /gene="lacA"
                     /locus_tag="VQT46_001622"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET2371620.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1141..1656
                     /gene="lacB"
                     /locus_tag="VQT46_001623"
     CDS             1141..1656
                     /gene="lacB"
                     /locus_tag="VQT46_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET2371621.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1667..2596
                     /locus_tag="VQT46_001624"
     CDS             1667..2596
                     /locus_tag="VQT46_001624"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET2371622.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDDQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKLVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLEELKEVLQESLFTGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAGLLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2598..3578
                     /gene="lacD"
                     /locus_tag="VQT46_001625"
     CDS             2598..3578
                     /gene="lacD"
                     /locus_tag="VQT46_001625"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET2371623.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKILVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            3812..4648
                     /locus_tag="VQT46_001626"
     CDS             3812..4648
                     /locus_tag="VQT46_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET2371624.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENH
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALIQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4684..5001
                     /locus_tag="VQT46_001627"
     CDS             4684..5001
                     /locus_tag="VQT46_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET2371625.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5003..6697
                     /locus_tag="VQT46_001628"
     CDS             5003..6697
                     /locus_tag="VQT46_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET2371626.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERSGKSNDELKEKVAANFNTAKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQAQFD"
     gene            6906..8312
                     /gene="lacG"
                     /locus_tag="VQT46_001629"
     CDS             6906..8312
                     /gene="lacG"
                     /locus_tag="VQT46_001629"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET2371627.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPSDVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8355..8537
                     /locus_tag="VQT46_001630"
     CDS             8355..8537
                     /locus_tag="VQT46_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET2371628.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQQS"
     gene            complement(8815..9576)
                     /locus_tag="VQT46_001631"
     CDS             complement(8815..9576)
                     /locus_tag="VQT46_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET2371629.1"
                     /translation="MLKQEKLAKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQT46_001632"
     CDS             complement(9758..10720)
                     /gene="nrdF"
                     /locus_tag="VQT46_001632"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET2371630.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQT46_001633"
     CDS             complement(10908..13067)
                     /gene="nrdE"
                     /locus_tag="VQT46_001633"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET2371631.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQT46_001634"
     CDS             complement(13148..13366)
                     /gene="nrdH"
                     /locus_tag="VQT46_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET2371632.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13717..13980
                     /locus_tag="VQT46_001635"
     CDS             13717..13980
                     /locus_tag="VQT46_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET2371633.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            13986..15719
                     /gene="ptsP"
                     /locus_tag="VQT46_001636"
     CDS             13986..15719
                     /gene="ptsP"
                     /locus_tag="VQT46_001636"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET2371634.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            15974..>16071
                     /locus_tag="VQT46_001637"
     CDS             15974..>16071
                     /locus_tag="VQT46_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2371635.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTV"
BASE COUNT         5025 a         2818 c         3331 g         4897 t
ORIGIN      
        1 aactagaatt ctagttttgc aggaagtcta ataaagaaac tagcaaggtc aggccttact
       61 ttattggtgg acatccagga tttaattgtc ttctacttga tgatgaagtc tatgaagatt
      121 attatctaga gtttgagaaa gaagagattt gctctgttcc acgtcctttc ccagaaacag
      181 gtatgttgga tttccaagat agaagtccat ggctagaggg acaaaaagaa atagatctta
      241 gttatgatct tttcagcaca gatgcagtga ctttggatga attgcaatct cgaacaattg
      301 cccttcgttc tcttaaacat gataagggat tgaaagtgca ttttgcagaa tttccaaacc
      361 tcatcatctg gtcaactttg aacaagggac ctttcattac ctttgaacca tggtctggct
      421 tgtcaacatt ccttgaagaa ggagatcatt tagaagataa gaagaatgtt tgtctcttag
      481 aagccaatca ggttgaagaa ttagggtttg agatagaagt tttataaaaa aagtaaaaaa
      541 taaataacaa aaacaaacac aaactgttga cttcttcaaa caatagtagt atattatgtt
      601 tgtgaggact aattgactgt tttttaaaga cagccaatac actgctggaa tccagcatag
      661 aaaaaataaa aaggagtata caatatgtct attgttatcg gtgcagatgc tgcaggtttg
      721 agattgaaag aagttgtgaa agacttctta gaaaaagaaa acttccacct tgtggatgtt
      781 acagctgaag gtcaagactt tgttgatgtg actctcgctg ttgctgcaga agtaaacaaa
      841 gaagaacaaa accttggtat cgtgattgat gcttatggag ctggtccatt tatggttgca
      901 actaagatca aaggaatggt tgctgcagaa gtatctgacg aacgttcagc ttatatgact
      961 cgtggccaca acaactcacg tatgatcact atgggggcac aacttgttgg tgatgaattg
     1021 gctaaaaaca tcgctaaagg atttgttaat ggtaaatacg acggtggacg tcatcaaatc
     1081 cgggttgaca tgttgaacaa aatgggctaa ttagattaca gtaagaaagg taagttaaaa
     1141 atgagaattg caattggatg cgaccacatc gtaacagatg aaaaaatggc ggtttcagaa
     1201 tttttgaaat caaaaggata tgaagtcatt gactttggta catatgacca tacacggact
     1261 cactacccaa tctttggtaa aaaagtaggg gaagctgtaa ctagcggcca agctgatctt
     1321 ggggtatgta tctgtggtac tggtgttggt atcaacaacg ctgtaaataa agttccaggt
     1381 gttcgttctg ccttggttcg tgatatgaca acagcccttt atgctaaaga acaattgaac
     1441 gctaacgtta tcggctttgg tggtaagatt actggtgaat tgcttatgtg tgatatcatc
     1501 gaagctttca ttcatgctga atacaaacca tctgaagaaa acaagaaatt gattgcgaaa
     1561 attgaacacc ttgaaagtca caatgctcaa caaacagacg caaacttctt tacagaattc
     1621 cttgaaaaat gggatcgcgg agaataccac gactaagagg tgacctatga ttttaacagt
     1681 cacaatgaac ccatccattg atatttccta tcccttggat gagttgaaga ttgatactgt
     1741 caatcgtgtg gtggatgtaa ccaaaacggc tggtggtaag ggacttaatg ttacccgagt
     1801 actttcagaa tttggtgatt ctgttcttgc tactggttta gtgggtggca aacttggtga
     1861 gtttttggtt gaacatatcg atgatcaagt aaagaaagat ttcttttcta ttcagggaga
     1921 aactcgtaac tgtatcgcta ttctccacgg tgacaaccaa acagaagttc ttgaaaaagg
     1981 tcctgaagta ttggaacagg aaggtcaaga ctttttggaa catttcaaaa aactcttgga
     2041 gtcagttgaa gtagtagcca tctcaggtag tctgccagct ggccttccag ttgattacta
     2101 tgcgagcttg gtagagcttg ctaatcaagc tggcaagcta gtagtcttgg actgctctgg
     2161 tgcagcactt caggcggttc ttgaatcacc ccataaaccg acagtaatca aacccaataa
     2221 tgaggaattg tctcagcttc taggaagaga agtttctgag gatttggagg aattaaaaga
     2281 agtccttcaa gaatctttgt ttacagggat tgaatggatt atcgtttcac ttggtgccaa
     2341 cggtactttt gccaaacatg gtgacacttt ctacaaggta gatattccta gaattcaggt
     2401 ggtaaatcct gttggatctg gagactctac tgtggcagga atttcttcag gacttcttca
     2461 caaagaatcg gatgcaggat tactcatcaa ggcaaatgtc cttggtatgc tcaatgctca
     2521 agaaaaaatg actggtcatg tcaacatggc caactatcaa gctctatatg atcaattaat
     2581 agtaaaagag gtataaaatg gctttaacag aacaaaaacg tgtacgctta gaaaaacttt
     2641 ctgatgaaaa tggtatcatc tcagctcttg catttgacca acgtggtgct ttgaaacgcc
     2701 tcatggctca acaccaaaca gaagaaccaa ctgtggccca aatggaagaa cttaaaatct
     2761 tggtagcaga tgaattgact aaatacgctt catctatgct tcttgaccct gagtatggac
     2821 ttccagcaac taaggctctt gatgaaaaag ctggtcttct ccttgcttat gaaaaaacag
     2881 gttatgacac aacaagcaca aaacgcttgc cagactgctt ggatgtttgg tctgcaaaac
     2941 gtattaaaga agaaggtgca gatgcagtta aattcttgct ttactatgat gtagatagct
     3001 cagacgaact caatcaagaa aaacaagcct acatcgaacg catcggttct gagtgtgtgg
     3061 ctgaagatat cccattcttc cttgaaatcc ttgcttacga tgaaaaaatt gcggacgcag
     3121 gttctgtaga atacgctaaa gtaaaaccac acaaagttat cggtgctatg aaagtctttt
     3181 cagacccacg ttttaacatt gatgtcttga aagttgaagt tcctgttaac attaaatatg
     3241 ttgaaggctt cgctgagggt gaagtggttt acacacgtga agaagcagca gccttcttca
     3301 aagcgcaaga tgaagcaacg aacttgccat acatctactt gagtgctggt gtatcagcta
     3361 aactcttcca agatactctt gtatttgctc atgaatcagg tgcaaacttt aacggagttc
     3421 tttgtggtcg tgctacatgg gcagggtcag ttgaagctta catcaaagat ggtgaagcag
     3481 cagctcgcga atggcttcgc acaactggat ttgaaaacat tgatgagctc aataaagttc
     3541 ttcaaacaac agcgacttca tggaaagaac gtgtgtaaga aagtcctcct agtttaggaa
     3601 catgaatcta aaaaaattta aaaaaagttg tatgtaaagg tttacaaaat aacttacttg
     3661 tgctatactt aaatcacaag ttaatacaag gtgagtgtta ctaagtaata ttaggcatga
     3721 tcacaggtga attagaaatc agctgatttt ctagttcatt tgtggtcatt ttttgtactc
     3781 atataccttt aagatataaa aggaggttga catgtatcga attctaaatc caatgaatca
     3841 caatgtctcg cttgtcagaa atgataaggg agaagaggtg attgtaattg gtaaggggat
     3901 tgcattcgga aagaagaagg gggatttgat tgctgaaaat catgttgaga aaatctttcg
     3961 gatgaagacc gaagagtcca gagaaaactt tatggctctt ctcaaagatg ttccgcttga
     4021 ttttatcaca gtgacctatg aaatcattga taagctatca aagaaatatc attatccgat
     4081 tcaagagtat ctctatgtaa ccttgacaga tcatatttac tgttcttatc aagctctaat
     4141 tcaaggaagg tacaaggata gtaatctgcc agatatttct gctaagtatc ctgtcgcttt
     4201 tcaaatcgca aatgaagctt ttgaaattta ccgtcagaag ctagcagatc attttcctga
     4261 ggacgaaatt attcggattg cttatcattt cattaatgct gaaggtgaaa atgaagtgga
     4321 acttgtggag tcgattgata agaggaaaga aattctcagg aatgttgaag aagttttaac
     4381 ggactatgca attcaacgaa ctaaaaagaa taaccatttc tatgatcgct ttatgatcca
     4441 tttgaattat ttcttggatt atttagacag atctagagat gataaccaat cacttctgga
     4501 tatggaagat catattaaac aatcctatcc aaaagccttc gagattggtt ccaagatcta
     4561 tgatgtgatt acgcaacata cgggtcttga tttgtataaa agtgaacgag tttatctagt
     4621 tctacatatc caacgtttat tgtcataaaa atttatttaa aactatataa ggagaattct
     4681 atcatgaata gagaagaagt aacattgtta ggttttgaaa tcgtagccta tgctggcgat
     4741 gctcgttcaa aactattgga agccttgaag gctgctgaag ctggtgattt tgaaaaagcg
     4801 gacgctctgg tagaggaagc tggtagctgt attgcagagg ctcaccacgc gcaaacaagt
     4861 ctattgacta aggaagcttc tggtgaggac ttagcgtata gtgtgaccat gatgcatggt
     4921 caagatcact tgatgacaac tatcttgtta aaagacctaa tgcaccattt aattgaactt
     4981 tacaagagag gagttaaata aaatggataa gttaataatt tttattgaga aaggaaagcc
     5041 tttctttgag aaattatcga gaaatatata cttaagagcg ataaaagatg gttttatttc
     5101 cagtatgcca gcagtattat tctcaagtat ttttatacta atagctgctg tgcccaatat
     5161 ttttgggttt aaatggtctg atgaacagtt agcttttatt ttgaaacctt acaactactc
     5221 aatggggatt ttagctctct tagtagctgg gacaactgca aaatcgttaa cagattcagt
     5281 taatacacgt agtatggaga aaaccaacca aatcaactac atgtcaactt ttttagcagc
     5341 tgttgttgga ttgttaatac tggcagctga tccaattgaa ggtggatttg ctaatggtct
     5401 tttaggtact agaggattac ttactgcatt tttggcagct tttattacag taaatatcta
     5461 taaagtatgt attaaaaata atgtaaccat tagacttcct gaagaggttc caccaaatat
     5521 tgcacaagtt tttaaagatg ttattccgtt tgccttatct gttctttcaa tatatggatt
     5581 ggatttaatt gttagaaata tttttggtac aaatgtagca gaatctgttg gtaaaatatt
     5641 agcccctcta ttttcagcta ctgatggtta tatcggttta gctattgtat ttggtgctta
     5701 tgctttcttt tggtttgttg gaattcatgg gccatctgtt gtagaacctt taattgtagc
     5761 tatcagttat gcaaatatag aagctaatgt tcagcttgtg caagctggta tgcacgcaga
     5821 taaaatttta aatccagtta ctcaaacttt tgttgtaaca atgggtggta ctggtgcaac
     5881 actagtagtt ccatttatgt ttatgtggtt atgtaaatca aaaagaaata gaattgtcgg
     5941 acgtgcgtct gtagttccta ctttctttgg cgtaaatgaa ccaatcctat ttggtgctcc
     6001 aattgtttta aatcctatct tctttattcc gtttgttact gctcctatta tcaatgtttg
     6061 gattatgaaa ttttttgtag atgttctaca aatgaatagt ttcagtatta ttttaccttg
     6121 gacaacacct gctccaattg gtattgttat gggaacggcg ctggctccat tgtcattcgt
     6181 cttggctata actttaatca ttatcgacac tttaatctat tatccatttg ttaaagttta
     6241 tgaccatcaa attttagaag aagaacgttc aggtaagtct aatgatgaat tgaaagaaaa
     6301 agttgctgca aacttcaaca ctgcaaaagc ggatgctatt cttgaaaaag cgggtgtcga
     6361 tgcagcacaa aataccatca ctgaagaaac aaatgtcctc gttctctgtg caggtggagg
     6421 aacaagtggt ctccttgcaa atgctttgaa taaggcagca gcagaataca atgtccctgt
     6481 gaaagcagca gcaggcggct atggtgctca ccgtgaaatg ttaccagagt ttgatcttgt
     6541 tatccttgcc cctcaagttg cttcaaactt tgaagatatg aaagcagaaa cagataagct
     6601 cggtattaaa ctagcgaaaa cagaaggcgc tcaatacatc aaattaactc gtgatggaaa
     6661 aggtgctctt gcattcgtac aagcgcaatt cgattaaggc tagagactct gaaatagtct
     6721 cctatcgtta cggaaatcgc tatggcgaat ttcctattat taattcgtcg gtaaaaagat
     6781 atcgttttta cctcctcatg tcacaattcg gtgacttggt acaagaagtg agatggagaa
     6841 ggatggctca ctgactcctc tcctctcact tttactttat ttaaatcaag aaataggtga
     6901 aaaaaatgac aaaaacactt ccaaaagact ttatttttgg tggcgcaaca gctgcctatc
     6961 aagcagaagg tgctacacat actgatggta aaggaccagt agcgtgggat aaatatcttg
     7021 aagataacta ctggtacact gcagaaccag ccagtgattt ttacaatcga tatccagttg
     7081 acctcaagct agcagaagag tatggtgtca atggtattcg aatttctatt gcttggtcac
     7141 gtattttccc gactggttac ggccaagtaa atgctaaagg tgttgagttt tatcataatt
     7201 tatttgcaga gtgtcacaaa cgtcatgttg agccctttgt aactcttcat cactttgaca
     7261 cgccagaagc tctccactca aatggagact tcttaaaccg tgaaaatatc gaacattttg
     7321 tagactacgc tgccttctgt tttgaagaat ttccagaagt aaactattgg acaaccttta
     7381 atgaaattgg gccaattggt gatggtcaat acttggttgg gaaattccct ccaggtattc
     7441 agtacgacct tgccaaagtc ttccaatcgc accacaatat gatggtgtct catgcgcgtg
     7501 cagttaagct atataaagat aaaggctata aaggcgaaat tggtgttgtt cacgctctgc
     7561 caactaagta tcctttagat cctaaaaatc cgtcagatgt tcgtgcagct gagttggaag
     7621 atattattca caataaattt atcttggatg caacttatct aggtcgctat tcagctgaaa
     7681 cgatggaagg tgtcaaccat atcttatcag tcaatggtgg tagcttggat cttcgtgaag
     7741 aagattttac agcattagaa gcagcaaaag acttgaatga tttccttgga atcaactact
     7801 atatgagtga ctggatggaa gcctttgatg gagaaactga aattatccat aatggtaagg
     7861 gtgagaaagg aagttctaaa taccaaatca aaggtgttgg tcgtcgtgta gctcctgatt
     7921 atgtaccacg tacggattgg gattggatta tctaccctca aggtttatat gaccaaatta
     7981 tgcgtgtgaa gaaagattat cctaactaca agaagattta catcactgaa aatggtctcg
     8041 gctataaaga tgagttcgtc gataacactg tttatgatga tggacgtatt gattatgtga
     8101 aacaacactt ggaggtcttg tctgatgcga ttgcagatgg agcgaatgta aaaggttact
     8161 tcatttggtc attgatggac gtcttttcat ggtcaaatgg ttatgaaaaa cgttacggtc
     8221 tcttctatgt agactttgaa actcaagaac gttatccgaa gaaatcagct cactggtaca
     8281 agaaagtagc ggaaactcag attatagact agtagaatta gtcattagat atagaatttt
     8341 agtgagtcaa aaagatgttc aaagatttta tccaatctat ttatgaaaaa gtttatatta
     8401 taaatttcga aaaatgctct caaataccgt gtttgacgag tgaagaattg aaaagtctat
     8461 ttttaaattt tatcaatcct gaagaatggg atactatctc ctttgattca gattttatgc
     8521 catttcaaca atcgtaacca atttctcaaa aaagttaaat cttatattta gtactctgca
     8581 aaactcttat ctaatcacgt tgcttatact caatgaaaat caaagagcaa ctttaaacta
     8641 ggaagcgagt cgcagatttc tcaatgcata gctttgagga attgggcaaa aagtctttga
     8701 tatagaaaaa gcatagtatc aggtgtttca acacctgata ctatgctttt tattgtggga
     8761 agatttactt tttttcttct gaaattgagt tgttacccag gctctttcag tttattaagg
     8821 cttgatgact ttaatgtgtt tagatagctt aaaaaggatt gaatcactta gtttagaatc
     8881 tgaaacaata gtatcaagat ttgatacatt ataaaaagta taaaaatcaa acttattgaa
     8941 cttactatga tctgcgagta aatatttttt attagaatta tttaaagcga tgcgttgagc
     9001 ctctccctct tcctcgctaa aagtagctag agctccgttt tgaataccat tacagctaac
     9061 gaaagcttta gaaaattgga gattagagag attttgtagg gtcaatgtgc caacaaaagc
     9121 acctgtaata tcgcgataat ttccacctat caaaatcaaa tctgttaatt ttcgttcgct
     9181 taaaatcaga aaaacaggta gactgttggt tacgacgcgg atattgtcaa taggcaactc
     9241 acgcgcaaaa aactctaatg ttgttcctgg tccaatgaaa atagtttctc tttcttctac
     9301 tagactgcct gcaaaatggg ctatttcttg tttttctgcc gtttggaggg cttgtttttc
     9361 aatatttgat cgctcattag tcaaaaggga gttggttcga agtttttcag ctccaccatg
     9421 cacacgaatc agcaaatctt tatcagctaa ttcctgtaaa tagcgccttg cagtcatatc
     9481 tgaaacggct atttcgtcca taatctgttt aactgttatg gttcctttac tatttactat
     9541 ctctaaaatt ttggctaatt tttcttgttt gagcatatta tcacctcgtt tcctactact
     9601 atcttaccat aaacaaactc atcattcaaa tacaaaaaca acaaaatgaa acaaaaacaa
     9661 aaatatcgaa gtttgttttc aaaactttcg atatttttgt tgggttataa ctttgatgtt
     9721 tctagtttac tttttgatga ttgagagtga tggagaatta gtctaaaccg tagttatagt
     9781 catcgtcttg catggcttca acttcgccaa gaaggtaacc atttccgact tgagagaaga
     9841 agtcatggtt ggaagttcct gttgaaatac cgttcataac gattgggttg acatcttcag
     9901 ctgaatctgg gaaaagtgga tcttgtccca tgttcatgag agctttattg gcattgtagc
     9961 gaaggaaggt tttaacctct tcagtccaac caacaccgtc ataaagactc tctgtgtagc
    10021 cttcttcatt ttcataaaga gtatagagta ggtcgtacat ccattctttg agtttttctt
    10081 gctcttcttc aggcaattca ttgaaaccaa gttggaattt gtaaccaatg taggttccgt
    10141 gaacagactc gtcacgaata atcaatttaa tgatttctgc aacgttggct agtttgttgt
    10201 taccgagata gtagagggga gtgaagaaac cagagtagaa gaggaaggtt tcgaggaaga
    10261 cgctggcaac tttcttttca agtgggctgc cgtttaggta gatttcgttg acaatctcag
    10321 ccttcttttg taggtaagga ttggtattgg tccattcgaa aatttcttca atctcagcct
    10381 tagtattcaa ggtagaaaag attgatgagt aagatttagc gtggacagat tccataaatt
    10441 ggatgttatt gaaaacagct tcctcatgtg gtgtacggat gtctgcgcga agggcttgaa
    10501 ccccagtttc agattgcata gtgtcaagaa gggttaaacc accaaaaact tttccgacca
    10561 agtctttctc tttgttagat agctttctcc agtcatccaa gtcgtttgat aagggaatac
    10621 gtgtatcgag ccaaaattgc tccgtcagtt tttcccaagt tgatttgtcg atgacatctt
    10681 cgatggcatt ccagttaatg gctttgtagt aagtttccat ttaaaatctc tttctgtgtt
    10741 tagtattgcg aactcacaat tatttctact ttaccataat tctataggag tatcgcacaa
    10801 aaagtcggaa gcccgacttt taaaatgtta cataaattat gttatgacat agtagatttg
    10861 attttatcag tgctgcttag ggaaaaataa tgtttctatg ctagaaacta aatcacacag
    10921 ctttcacatt ggttggcgcc gacttctcca ccgtcatctg taaaggtacg gacgtagtag
    10981 atagacttga ttcccttgtt aaaggcatag ttacgaagga tggacaagtc acgtgtcgtt
    11041 tgtttatttt ccctcttcca ttcgtaaagg ccttttggaa tgtcactacg catgaagagg
    11101 gtgagtgaaa gtccttgatc cacgtgttca gtcgcagcag cgtaaacatc gatgacttta
    11161 cgcatatcca tatcgtaggc agaagtgtag taaggaatgg tttctgtaga caagccagca
    11221 gcagggtagt agattttacc aattttcttc tcttggcgtt cttcgatacg ttgcgtaatc
    11281 gggtggatag aagcagaaac gtcgttgata tagctgatag aaccatttgg cgctacagca
    11341 aggcgatttt ggtggtaaag accatcttct tgaaccttgt cgcgaagttc agcccaatca
    11401 gcaacaccag ggataaagac atttttgaag agttctttaa cacggtctga tgttggaaca
    11461 aattcaccag ttacatactt gtcaaagtaa cttccgttag catagtctga tttttcaaag
    11521 ttgtggaagg taataccacg ttcacgcgca atattgtttg actctaccaa ggtccagtag
    11581 ttcataagca taaagtagat gcttgtaaat tcaacagact caggtgaacc atattcaatg
    11641 agttgttggg caaggtagct gtgcagtccc atggcaccga gaccaaaggt gtgggcttgg
    11701 ctatttccat ggtcaatcgt tggtacagct acgatatgtg aactatctgt aacgaaagta
    11761 agggcacgaa ccatagcacg gatagaacga ccaaaatcag gtgaagtcat catgttaacc
    11821 acgttggttg aacccaggtt acatgaaaca tctgttccca tttgaaggaa ttcttgagca
    11881 tcgttgatca agcttggttc ttgaacttga agaatctcag aacacaagtt actcatgata
    11941 atctttccat caacaggatt tgcacggtta gccgtatcga tgttgactac ataaggatag
    12001 ccagactctt gttgcaattt agagatttca gtttccaaat cccgcgcctt gatttttgtc
    12061 ttgcgaatat ttggatttgc gaccaattca tcgtattttt cagtaatgtc gatgtaattg
    12121 aatggcacac cgtattcttt ttctacagag taagggctga agaggtacat ttcttcattt
    12181 ttacgagcca attcgtagaa tttatcaggt actacaacac caagtgatag agtcttgaca
    12241 cgtacttttt catcagcgtt ttctttctta gttgaaagga aagcgatgat atctgggtga
    12301 aagacgttga ggtagacaac accggcacct tgacgttgcc ccaattggtt ggagtaagag
    12361 aagctgtctt caaaaagctt cataacagga acgacacctg aagcagctcc ttcatagcct
    12421 ttgataggtg caccagcttc acgaaggttg ctgagggtaa ttcccacacc accaccaata
    12481 cgtgaaagtt gaagagctga gttgatagaa cgtccgatag agttcatatc atccgtcact
    12541 tggattagga aacaagatac caactctcca cggcgagcac gtccagcatt caagaaggaa
    12601 ggagtagcag gttggtagcg ttggtggatg atttcattgg caatatcgat tgcaacagct
    12661 tcattcccat cagcgaaata aagggcgttg aagaagacac ggtcttccat attttcaaga
    12721 tagtattcac cgtcattagt ctttaaggca tattgattgt aaaatttata agctgccatg
    12781 aatgacttga attggaagtt ttggtctttg ataaattgag ctaattcttc caagaactct
    12841 ggacggtatt tcttgataaa ggctgtttcg atgtagttgt gttcaatgag gtaattgatt
    12901 ttgtctttga ttgaatcaaa aaccatagtg tttggaacta cattttcttt aaagaaagca
    12961 tccaaggctt ccttgtcttt atgaagcatg atttgtccat taacaggacg gttaatttcg
    13021 ttattaagac ggaagtaagt cacgtcttca agatgtttta atcccataaa atttccctta
    13081 tctaattaca aaagaaaggc ttctaagtta gccctaaaag cagtttcttc tggatgatgt
    13141 actaagatta tgctaattgt ttcagttttc ctggttggaa acctgaaaag acttcagttg
    13201 gtgtttggat aacaggagct gcgctaaaac cgagctcttt aacttgatcg acgtactcag
    13261 gttgctcatc aagattgatt tcacgataag agacattatt actgtccaag aaacgcttgg
    13321 tcattttaca ttggacacaa ttgtttttag aataaacggt taccattgtg taactcctct
    13381 tcaaaattta atactatctt agtatatcag aaaataaaat tttgtcaatg atttgaacta
    13441 aatatagtgg tgttcttttg ttgtttttat atataaacac aatatatagt gtttgtattg
    13501 tgaaatagca atgattatcc tataaattgt ttttaaagaa actatatcct gtgttttgtt
    13561 atctaggata gaagattttc agcaagttat ctgaaaggaa attgaaggaa aatccagaaa
    13621 atgcttgaaa aaaatcctag aagatggtat aatactaaat tgtaagggtt atcacatata
    13681 actcaaaaaa agaaagaaca aaaggagagt caaactatgg cttctaaaga tttccacgta
    13741 gtggcagaaa caggtattca cgcacgtcca gcaacattgt tggtacaaac tgctagcaaa
    13801 tttgcttcag atatcactct tgagtacaaa ggtaaatcag ttaaccttaa atcaattatg
    13861 ggtgttatga gtcttggtgt tggccaaggt gctgacgtaa ctatctcagc tgaaggtgca
    13921 gatgcagatg acgctatcgc tgcaatctca gaaacaatgg aaaaagaagg attggcataa
    13981 gggaaatgac agaaatgctt aaaggaatcg cagcatctga cggtgttgca gttgcaaaag
    14041 catatctact cgttcagccg gatttgtcat ttgagactat tacagtcgaa gatacaaacg
    14101 cagaagaagc tcgccttgat gccgctctac aggcatcaca agacgagctt tctgttattc
    14161 gcgagaaagc agtaggtacg ctcggtgaag aagcagctca agtttttgat gctcacttaa
    14221 tggttcttgc tgacccagaa atgatcagcc aaatcaagga aactatccgt gcgaagaaag
    14281 tgaatgcaga agcaggtctg aaagaagtta cagatatgtt tatcactatc tttgaaggca
    14341 tggaagacaa cccatacatg caagaacgcg cagcggatat ccgcgacgtg acaaaacgtg
    14401 tattggcaaa ccttcttggt aaaaaattgc caaacccagc ttctattaat gaagaagtga
    14461 ttgtgattgc gcatgacttg acaccatctg atacagctca attggacaaa aactttgtaa
    14521 aagcttttgt aaccaacatt ggtggacgta caagccactc agctatcatg gcacgtacac
    14581 ttgaaattgc tgctgtatta ggtacaaata acatcactga aatcgttaaa gacggtgaca
    14641 tccttgctgt taacgggatc actggagaag tgattatcaa cccaacagat gaacaagcgg
    14701 cagaatttaa agcagctggt gaagcctatg cgaaacaaaa agctgaatgg gcacttttga
    14761 aagatgctca aacagtgact gctgacggta aacacttcga gttggctgcc aatattggta
    14821 ctccaaaaga cgttgaaggt gttaacaaca acggtgcaga agctgttgga ctttaccgta
    14881 cagagttctt gtacatggat tctcaagact tcccaactga agatgagcag tatgaagcat
    14941 acaaggctgt tcttgaagga atgaacggta aacctgttgt cgttcgtaca atggatatcg
    15001 gtggagataa ggaacttcct tacttcgata tgcctcacga aatgaaccca ttccttggat
    15061 tccgtgctct tcgtatctct atctctgaga ctggagatgc tatgttccgc acacaaatcc
    15121 gtgctcttct tcgtgcgtct gttcacggtc aattgcgtat catgttccca atggttgcgc
    15181 tcttgaaaga attccgtgca gcgaaagcag tctttgatga agaaaaagca aaccttcttg
    15241 ctgaaggtgt tgcagttgcg gataacatcc aagttggtat catgatcgag attcctgcag
    15301 cggctatgct tgcagaccaa tttgctaaag aagttgactt cttctcaatt ggtacaaacg
    15361 acttgatcca atatacaatg gcagcagacc gtatgaacga acaagtttca tacctttacc
    15421 aaccatacaa cccatcaatc ctacgcttga ttaacaatgt gatcaaagca gctcacgctg
    15481 aaggtaaatg ggctggtatg tgtggtgaga tggctggtga ccaacaagct gttccacttc
    15541 ttgtcggaat gggcttggat gagttctcta tgtcagcaac atctgtactt cgtacacgca
    15601 gcttgatgaa gaaactcgac acagctaaga tggaagagta cgcaaaccgt gcccttacag
    15661 aatgctcaac aatggaagaa gttcttgaac ttcaaaaaga atacgttaat tttgattaat
    15721 cgaaaagtcc ctgcaactca gttacaggga ctttttttga tattttaaaa agaattttca
    15781 agaaaatctt tcttataaaa agtccaacct tgaaaaagta gtggtcagaa caaaaaatac
    15841 ttaaatggtt cataaaattc ttgacaagtt ggagatttag gagtaaacta ttaaccagtt
    15901 aagtaataga gaggagtttc tgcaatttag aaatgaattg caactagaaa tatcaaatag
    15961 aaagagagtt tcgatgaaaa ttaataagaa ataccttgtt ggttctgcgg cagctttgat
    16021 tttaagtgtt tgttcttacg agttgggact gtatcaagct agaacggtta a
//
LOCUS       DAVAZV010000051        15999 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVAZV010000051 DAVAZV010000000
VERSION     DAVAZV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15999
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.051"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(7..1221)
                     /locus_tag="VQT46_001638"
     CDS             complement(7..1221)
                     /locus_tag="VQT46_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2371636.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(1377..1670)
                     /locus_tag="VQT46_001639"
     CDS             complement(1377..1670)
                     /locus_tag="VQT46_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371637.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVKVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            1832..2284
                     /locus_tag="VQT46_001640"
     CDS             1832..2284
                     /locus_tag="VQT46_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET2371638.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(2319..3707)
                     /locus_tag="VQT46_001641"
     CDS             complement(2319..3707)
                     /locus_tag="VQT46_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET2371639.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            3773..4735
                     /locus_tag="VQT46_001642"
     CDS             3773..4735
                     /locus_tag="VQT46_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET2371640.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(4732..4923)
                     /locus_tag="VQT46_001643"
     CDS             complement(4732..4923)
                     /locus_tag="VQT46_001643"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371641.1"
                     /translation="MNTIERTRRLVKGCATHCFEVVDETDEVSSKHVFEVVDRTDEVS
                     NHTYGRATLTWFAEIFEEY"
     gene            complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQT46_001644"
     CDS             complement(4987..5997)
                     /gene="ccpA"
                     /locus_tag="VQT46_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET2371642.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKVGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(6422..7021)
                     /locus_tag="VQT46_001645"
     CDS             complement(6422..7021)
                     /locus_tag="VQT46_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2371643.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(7022..8119)
                     /locus_tag="VQT46_001646"
     CDS             complement(7022..8119)
                     /locus_tag="VQT46_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET2371644.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLFWGIMLIYVAGNTAFVAVNYIWFFFFLSNLLSYHFSVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYLLGILTFVDLMTLGSVRIRLVEDLKEAQ
                     TKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQIQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVEIANQLDTASLTQEL
                     ESTASMILLELVTNIIKHAKASKAYLKLERTDQELLLMVRDDGKGFETVTENELHTVR
                     ERVLPFSGEVSVISQKHPTEVQVRLPYKERK"
     gene            complement(8119..8856)
                     /locus_tag="VQT46_001647"
     CDS             complement(8119..8856)
                     /locus_tag="VQT46_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371645.1"
                     /translation="MKRWIALNKIEFLLTKRQSVYYLLSVGMPTAFYLFFSGMYQDTP
                     GGPANFMRDYLISMTAFSMMSTAIFSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMMVDYLVSILVVFSVGHLVRGVDMSLGSWIGAAFLLIVGSIAFVALGLTLTLLPSS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAIGKCLPTYQLMELLKTFLNEGSINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(8858..9742)
                     /locus_tag="VQT46_001648"
     CDS             complement(8858..9742)
                     /locus_tag="VQT46_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371646.1"
                     /translation="MNMIKVQGLHKNIKSKAILKDISFEVAEGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVYIQDLPVTSSKLDYTRSYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLNNQEIDQLLQFDQQQKEQFAEKLSGGQKRLLSFILTLIGRPKLVFLDEPTAAMD
                     TSTRQRFWEIVRDLKAQGVTILYSSHYIEEVEHTADRILVLNKGELIRDTTPLAMRSE
                     EIEKHFILPLAYKEVVEKSVLVENWVQKQDALQVVTCEADAFWELLVQAGCRIQEIEV
                     NNRSLLDTIFEETQKGDD"
     gene            complement(9729..9923)
                     /locus_tag="VQT46_001649"
     CDS             complement(9729..9923)
                     /locus_tag="VQT46_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371647.1"
                     /translation="MKKAILFLFIGLSLVVWLVEMFTGWFDQSFLHQVIRGAWGLGFM
                     ISVVFPMGMEWLKGEYYEHD"
     gene            complement(9920..10126)
                     /locus_tag="VQT46_001650"
     CDS             complement(9920..10126)
                     /locus_tag="VQT46_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371648.1"
                     /translation="MEEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEGFYHFPWELFAS
                     FGIMSWLIREGLKLVRDVKKELEK"
     gene            complement(10611..10684)
                     /locus_tag="VQT46_001651"
     tRNA            complement(10611..10684)
                     /locus_tag="VQT46_001651"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10648..10650),aa:Pro,seq:tgg)
     gene            complement(10700..10773)
                     /locus_tag="VQT46_001652"
     tRNA            complement(10700..10773)
                     /locus_tag="VQT46_001652"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10737..10739),aa:Arg,seq:acg)
     gene            complement(10783..10868)
                     /locus_tag="VQT46_001653"
     tRNA            complement(10783..10868)
                     /locus_tag="VQT46_001653"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10832..10834),aa:Leu,seq:taa)
     gene            complement(10876..10947)
                     /locus_tag="VQT46_001654"
     tRNA            complement(10876..10947)
                     /locus_tag="VQT46_001654"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10913..10915),aa:Gly,seq:gcc)
     gene            complement(10970..11042)
                     /locus_tag="VQT46_001655"
     tRNA            complement(10970..11042)
                     /locus_tag="VQT46_001655"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11007..11009),aa:Thr,seq:tgt)
     gene            complement(11061..11142)
                     /locus_tag="VQT46_001656"
     tRNA            complement(11061..11142)
                     /locus_tag="VQT46_001656"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11106..11108),aa:Leu,seq:tag)
     gene            complement(11148..11220)
                     /locus_tag="VQT46_001657"
     tRNA            complement(11148..11220)
                     /locus_tag="VQT46_001657"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11185..11187),aa:Lys,seq:ttt)
     gene            complement(11245..11317)
                     /locus_tag="VQT46_001658"
     tRNA            complement(11245..11317)
                     /locus_tag="VQT46_001658"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11282..11284),aa:Asp,seq:gtc)
     gene            complement(11320..11392)
                     /locus_tag="VQT46_001659"
     tRNA            complement(11320..11392)
                     /locus_tag="VQT46_001659"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11357..11359),aa:Val,seq:tac)
     gene            complement(11397..11512)
                     /gene="rrf"
                     /locus_tag="VQT46_001660"
     rRNA            complement(11397..11512)
                     /gene="rrf"
                     /locus_tag="VQT46_001660"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(11589..14490)
                     /locus_tag="VQT46_001661"
     rRNA            complement(11589..14490)
                     /locus_tag="VQT46_001661"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            complement(14615..14687)
                     /locus_tag="VQT46_001662"
     tRNA            complement(14615..14687)
                     /locus_tag="VQT46_001662"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14652..14654),aa:Ala,seq:tgc)
     gene            complement(14739..>15999)
                     /locus_tag="VQT46_001663"
     rRNA            complement(14739..>15999)
                     /locus_tag="VQT46_001663"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         4432 a         4010 c         3054 g         4503 t
ORIGIN      
        1 caagccctat ctacgatact gtttcaagaa acgagtcatc ttttcttgga tttgggctaa
       61 ctcatcaaca cgaggaaggt aaacgatacg gaagtggtct ggttcctgcc agttaaagcc
      121 tcgaccatga accaagagaa ccttttcctg cttcaagaaa tcaaggacaa actgctcatc
      181 atcatcgata cggtacatat tgcggtcgat ttttgggaag atatagagcc ccgccttggg
      241 tttaacggca gacaaacctg gaatatcttg aatggcatta tagatgaaat ttctttgctc
      301 gtagattcgt ccaccaggaa gaagcaattc atcgactgat tggtgacccc ccaaggaagt
      361 ttgtacgact tgttgggcca aaacgttaga gcaaaggcgc atattggaca gcatattgag
      421 cccttcgata tagcccttaa catgagtctt agggccagac aagaccatcc aacccacacg
      481 gaaacctgct atgcggtggg attttgacag accattcatg ctgacacaga agacatctgg
      541 tgccaagctc gccacaggcg tatgcacatg tccgtccatt accatgcggt catagatttc
      601 atccgcaaag ataatcaaat cgttttgacg ggcaatctca ataatctcca gcaagagttc
      661 cttaggataa agggctccag ttgggttatt tggattgata aggacaattg ccttggtatt
      721 ggaagtgatt tttgacttga tatcgtcaat atctgggtac cattccacag cttcatcaca
      781 gatatagtga acggcatttc ctccagctag gctgacagcc gccgtccata gaggatagtc
      841 tggcattggc actaagacct catccccatt gtccaaaagc ccctgcatgg acatgacaat
      901 caactcactg acaccatttc caaggtaaat atcatcaata tctacgtttg ggaatttctt
      961 cagctggcaa tactgcatga tggccttacg ggctgagaaa atccctttgg agtcagaata
     1021 gccttcacta tcacgcgcat tcataatcaa gtcatgaatg acctcgtctg gcgctgtaaa
     1081 gccaaattct gctggatttc ctgtattcag acgtaaaatc ttttctccat tcgctcgcat
     1141 ccgcatggct tcttccaata caggaccacg gatatcataa gcaacatgct ctaacttact
     1201 agacttgtta tattctttca tcttgtttcc tcaattcatc aggatagtaa cattatacca
     1261 ctagaaagag aatgcgacaa gtttactgaa atgtgttact agtttcgtat agaagaaaaa
     1321 ccttgctaaa ggcgaggtta agaacgtaga gatagcaggc attttgcaaa gacacatcac
     1381 ataccaaaag ataaacctag aaaaagcaag cctagaaagg agtcataaag aagattaaac
     1441 atgaggaaaa gcccccatat catcaagtaa tcccaacgcc cacttcgttt tgcaactaga
     1501 aataagatta gatggtagag tacatgaaag actaaaaatc caataaaact tggataaaga
     1561 agcggtacca gactctctaa ttgacagatc atgatcactt ttaccaagac tgaaactagg
     1621 ataattccat aatacaggaa atttgatttt tgaaaagagt ttttcatcat tctcccttcc
     1681 ttcacttctt tccttctatc ctttctttta ttttatcata tatttatata gattttaagc
     1741 cctaatattc ttttgaaaaa tacttttttt gctttacttc tatagtgaaa aggtttacaa
     1801 ttatagtaag aaaatttcag gaggtttcat tatggcacaa cgttaccaaa atatcatggt
     1861 cgcaatcgat ggttctaagg aagcggactt ggcttttgtc aagggagttc attctgctct
     1921 acgaaacgac gctaaactca ccatcgcaca tgtcattgac acacgcgctc tccaaagcgt
     1981 atccaccttt gatgctgaag tttacgaaga actccaagtc gacgctgaaa gtctgatgaa
     2041 agagtacgaa aaacgtgcta aagatgctgg ggtagcagat gttcatatcg tcattgaaat
     2101 gggaaatcca aagaccctgc tagcacgtac tattccagat gccgaggaag tggacctcat
     2161 cctcgttggc gcaactggtc tcaacgcctt tgaacgcctc ttggtcggct cttcatctga
     2221 atacatactc cgccatgcta aggtcgattt gctggttgtg agagaacaag aaaaaacctt
     2281 ataatcacaa agaaaaggag cccctagctc ctttttgttt acgatttatt tctctcttta
     2341 tggcgttcgt aagccttgag ctggcgctgc agttcctttt taatagcagg ttctggagca
     2401 tatttttctt cccaattatc tggttttaag attttatggg tcactggatc aaaatgagcc
     2461 ttgccatctg gaaaaatttt ccccatattg gcctgatgga caatatcaaa aatacgttct
     2521 gggtccaccc ccatcaagac aaaactgccg taggtgaagt aaagcgtgtc aatcaaggca
     2581 tccacttgcc ctatcaaatc ttgctgagca ggtgtcttct tggctacttt acctgctgcc
     2641 ttatcaaggg cctgatgaag ttgcgataca gcttgaccaa aatcttcttc agaaggactg
     2701 gctgctcgaa caaactccac caattcttct attttaaaac cagccctatg ggttgcaccc
     2761 tctaaatccc aagctcgagg ttcttcttgg gttcgttcat ccatcatgtg gtggaaggtc
     2821 ttgaccttat tgaaatgata gtcacggctg acaaagactt tttctgaaga caaaacacca
     2881 aaatgttcca aggccttgtg gatcccatct tgttgattgc tagtggtaat gtgcttggca
     2941 gcttccttga cactgctact accatttccc atagcgaccg acataccgac gccagccagc
     3001 atttcaaggt cattatctga gtcaccaaaa gccatgactt ggttgaggtc aaagccatat
     3061 tctttcccaa ctcggcgaat gccttctaat ttagaatttc cctgattgat gacatccgat
     3121 gcaaaaggat tgctacgtgt caatttcaag tcttcaaaat cagctgccgc cttctcagat
     3181 tcttctggtg tcatcagcat caaaacttgg tagataggct gattcatcag gtgaagcagg
     3241 tcctcttcct tttggggaac aaccttgctg accatgcgat taaaagactg actcaccgtc
     3301 cgagttaaaa cagagggaac gaagcgacta attcgttggg aaaaagaacc cagaccaaag
     3361 gacatgattt tagaacccaa catggcatcc ttggtcccta gggcaatctc cgtgccctct
     3421 tttttagcat agctaattag atggcgcaaa tgtaacttgg aaatagggct cgtgaacaag
     3481 actctgtctt tactaaagat atactggcca ttataggtta ccgcaaaatc cagatccaaa
     3541 tcgtccatca attccttaac aaaaaaaggt cctcgccctg tcgctacgcc aactagtacc
     3601 ccttgttctt tgacaatctt aatcgcgtcc ttagtggatt tcaaaacact cttgcgattg
     3661 ttgaccaagg ttccatcgat atcaaaaaaa acagctttga cttccatcct attccaatct
     3721 ccccttttgt gatacaatga ttataccaca tttcagaaag agtgagtaaa tcatgcctaa
     3781 gaaaatcctt gttttacata cgggtggaac tatttccatg caggccgatg cttctggcgc
     3841 tgttgtgacg agttcagata atcccatgaa ccatgtgtcc aacccacttg aaggaatcca
     3901 agtccacgcc ttggactttt ttaaccttcc aagtccccat atcaaaccca aacatatgct
     3961 ggtcctctac cagaaaatta aagaggaagc agataactac gatggagtgg taatcacaca
     4021 cggaaccgat actttagagg aaacagccta tttccttgat accatggaag ttccccatat
     4081 gcctatcgtt ctaacaggag ccatgcgtag ctccaatgag ctcggtagtg atggtgttta
     4141 taattaccta agtgctttac gagtggccag cgatgacagg gctgctgaca aaggagtttt
     4201 ggtcgttatg aacgatgaaa tccacgctgc caagtatgtc accaaaacac atacgactaa
     4261 tgtcagcacc ttccagactc caacacatgg ccccctcggt ctcatcatga aacaggaaat
     4321 cctctacttc aaaacagctg aacctcgtgt tcgctttgac cttgatcaca tacaaggttt
     4381 agtccctatc atctcggctt atgctggtat gacagatgag ctgattgata tgctggattt
     4441 agaacacttg gacggtttga ttatccaagc cttcggagct ggtaatattc ccaaagaaac
     4501 ggctcaaaaa ttagaaagcc ttctgcaaaa aggaatccca gtcgctctgg tatcacgatg
     4561 ctttaacggt attgccgagc ctgtttatgc ctaccagggt gggggcgtac agttgcaaaa
     4621 agcaggcgtt ttctttgtta aagaactcaa cgcccaaaaa gctcgcttga aactcctcat
     4681 cgccctcaat gccggactaa caggacaggc tttgaaagac tatatggaag gctaatactc
     4741 ttcgaaaatc tctgcaaacc acgtcagagt cgccctaccg tatgtatggt tactgacttc
     4801 gtcagttcta tctacaacct caaaaacatg ttttgagctg acttcgtcag tttcatctac
     4861 aacctcaaaa cagtgtgttg cgcagccttt aaccagccgc ctagtccgct ctatggtatt
     4921 cattaagtca acatctcttg tttaagagca caaaatcagg aaatcttctc gattccctga
     4981 ttttttctat ttacgttttc gtgttgagct acgttctgtc aaaccatgag gtaagagaac
     5041 ttcacgttct tccaactctt ccttatgcat aatcttggtc aacatacgca tactaatggc
     5101 accaaggtca taaagaggtt gggcaatcgt tgtcaagttt ggacgggtaa agcgtgagat
     5161 ttgtgaatca tcactagtaa taatttcaaa atcttctggc acagaaacac ccttatcagc
     5221 caaaccgttc aagactcctg ctgccaactc atcacctgtc acaactgctg cagttgcatt
     5281 tgatgaaatc aaacgctctg ctaaggcgta accatcatca tagctatatt tagattcaaa
     5341 taccaaaccc tcactataag tgattcctac ttttttcaag gtttccttgt agccaactaa
     5401 acgaacctta ccattgatgt catccactag cggaccgcta acgaaagcaa tacgctcatt
     5461 ttctttagca aggtagctca ctgcatcaat tgttgcttgc ttatagtcaa tattgacact
     5521 tggcaactgg tgctcaacat cgacagttcc tgcgagaaca atcggagtac gtgaacgcga
     5581 aaattctgag cgaattttat ctgtcaagtg ataacccata tagataatgc catctacctg
     5641 ctttgaaaag agggtattga caacagaaac ttctttctcg ttatcttcat cgctattagc
     5701 taggacaata ttgtacttgt acatttctgc aatatcatca atccccttag ccaaactcga
     5761 aaaataacca ttggtaatat ttggaatcac gacaccgaca gtggttgtct ttttacttgc
     5821 aagaccacgc gcaactgcat ttggacgata atccaaacga tcaattacct ctagcacttt
     5881 tttacgggta ttctctttta catttttatt gccattgacc acacggctga ccgtcgccat
     5941 ggaaacacct gcttcacgag cgacatcata aatggttact gtatcatctg cattcattcc
     6001 ttttcctgtc ctttctatct cacacattct tttacaagta gaggtactga ttgaagctct
     6061 atatctactt acaaaagtga agatgtgaaa atttcgtttt catatttcta cttattccat
     6121 tctatcacta attgtaaaca ctttcaagtg ttttttgaag attgattgaa aaaatttcat
     6181 agaaaaccta ggtttagctc cttgctacca ccttagacta aataaaaagg aggaaactaa
     6241 gcccttctaa agttatagta aaatgaaata agaacaggat aaatcgatca ggacagtcaa
     6301 atcgatttct aacaatgttt tagaagtaga ggtgtactat tctagtttca atctactata
     6361 ggtattgttc cattcactac cgtcaatttt agcacatagt cttcatgaaa atattatatc
     6421 atcataacca accagattct tttgcgatat tagctgcctc tgttcgatta ccagcatcca
     6481 gttttgaaag aatattggtg acatagtttc gaatagttcc gtttgagagg taaagctgat
     6541 ctgcgatttc ttggttggat aagccccggg cgattccctt taagacagca atctcttgtt
     6601 ctgtcaacgg attgggacgg gtcatcacca cttccatcaa ttcaggcgaa tactccttgc
     6661 gtccttcgag gacggtgtgc aaggtttgca tgaggtctgc aatgcttcgt tcctttaata
     6721 cataagcatc cactccagcc ttgaccgcac gttcaaaata cccagcacgc ttgaaggtcg
     6781 tcaccacaac cacctttgtt tcaagccttt ctgatcgtat ccactccaag acttcaagac
     6841 ctgtcttaac aggcatttct acgtcaagga tggcgatatc tacagactcc ttttctaata
     6901 gttggattgc ttcttgccca ttcttggctt gaaggacaga ctccacatct ggttgaagcg
     6961 tgagcaattg acacatagca tctcgcaaca tactttgatc ttctgcgact aatactttca
     7021 tctactttct ctccttataa ggtagtcgaa cttgcacttc cgttggatgt ttctgactga
     7081 ttacacttac ttctcctgaa aatggaagga cacgttctcg aactgtatgg agctcatttt
     7141 ctgttacagt ttcaaaacct ttcccgtcat ctctgaccat caggagcaat tcctgatctg
     7201 tgcgttctaa ttttaagtag gctttagacg ctttagcatg tttgatgatg ttggtcacta
     7261 attcaagcaa aatcatggaa gccgttgact ctaattcctg agttaagcta gctgtatcta
     7321 gttgattagc tatttccacc tcaattccag caatttctaa catctttttc acagtctcta
     7381 gttcggatgt caaagttcta gacttaagat tttccacaat ggttcgcact tcacgcattg
     7441 attctttgct aatctgctgt atttctctta attccttttc cacttgtgga taagcctgta
     7501 tttgaaataa ctgcaaggct agatcagttt taacactaag catagcaaag gtatgcccca
     7561 gactatcatg caaatcttga ccgatacgat tgcgctcatt ttctgctagc aatagattta
     7621 tctgggtatt ttgcttagtc tgagcttctt tcaaatcctc gacaaggcga attcgaaccg
     7681 agcccaaagt catcaaatca acaaaagtaa gaattccaag cagatagact agaaactcaa
     7741 cttcgattct ctgaaaaatc aaaagtcgcc ccacaacaag gacttgagca agaagaaaag
     7801 tccagacatg taaagacttt aaactacgta cgctgaaatg ataacttaag agattggaaa
     7861 ggaaaaagaa aaaccagata taattcacag caacaaaggc ggtattccca gctacataga
     7921 tcagcatgat cccccagaaa agccaagata ggcgctggct cttagttgtt aaaacaccca
     7981 aatatgccac tacaaataga atatcaatca ataaatgcca ggcagaaagc cacccagtca
     8041 ctacaggtag gatggggaaa atcataaaaa ttaaactggc ccaaaacata tagtgtatgc
     8101 ttttcagtct ttcaagcatt aagcattctc cttatgacct tgaaggtaaa tggtcaaacc
     8161 aaacaaaact gctgaaaaaa caagtagata aactgtggct gatagattga tgctaccctc
     8221 gtttaagaag gtcttgagca actccatcaa ctgataagtt ggtaggcact tcccgattgc
     8281 ttgcatccag tctggaaata aagagatggg catccagagt ccacctaaaa cagccaagcc
     8341 tagatagaga agattgccca cgacagacat cagctgacta gaaggcaaga gtgtcaaggt
     8401 caagccaagc gctacaaaag ctatacttcc tactatcagc aagaacgcag ccccaatcca
     8461 gcttcctaaa gacatatcca cacctctgac caagtgccca actgagaaaa caaccaggat
     8521 tgagaccaaa taatcaacca tcatacttgt tatctttgat agataatatt ctaccatatt
     8581 tacagggcta tgacgcaatg ttttctgcca gttgttcatc ttatcggtat gtaagacagc
     8641 tgggaatgaa aagatagcgg tcgacatcat ggaaaaggca gtcatggaga tgaggtagtc
     8701 gcgcataaaa ttagccggtc cacctggtgt gtcctggtac atgcctgaaa agaatagata
     8761 gaaggctgtc ggcatcccta cagataataa ataatagact gattgccgtt tggtcaatag
     8821 aaattctatc ttgtttagtg caatccatcg tttcatctta gtcatctccc ttctgtgttt
     8881 cttcaaagat tgtatccaac aaactacgat tattgacttc gatttcttgt atcctacatc
     8941 ctgcttgaac taacagttcc cagaaagcat ccgcttcgca tgtgactact tgtaaggcat
     9001 cttgtttttg tacccagttt tcaaccaaga ctgacttctc aacgacttcc ttgtaagcta
     9061 gcggaaggat aaaatgcttt tcaatctcct cactacgcat agctagaggc gtcgtgtcac
     9121 gaatcaactc tcccttattt aaaaccaaaa tccggtcagc tgtatgctct acctcttcaa
     9181 tataatgaga cgaatagaga atggtgactc cttgcgcttt taggtcccga acaatttccc
     9241 aaaaacgttg acgagttgaa gtatccatgg cagcagttgg ctcatctaaa aagacaagct
     9301 ttggtcgccc aattaaggtc aagataaaag ataaaagacg cttttgccca cctgacaatt
     9361 tttctgcgaa ttgctctttc tgttgctggt caaactgtaa tagttgatcg atttcctggt
     9421 tgttcaaggg atttggatag atacgttgaa agaaagcaat caactcttta acctttagtt
     9481 tttgaacaat tacattttct tgagggagat aggatctcgt atagtctaac ttagagctcg
     9541 ttaccggcaa atcttggata tatacttgcc cactggtgac caatttatct ccaagcaaac
     9601 agtccaagag tgtcgtctta ccagctccat ttggcccaat caaggcgacg cattcacctt
     9661 cagctacctc aaaggaaata tccttcaaaa tagccttact tttgatgttt ttatgtaagc
     9721 cttgtacctt aatcatgttc ataatattct cctttcaacc actccattcc catagggaaa
     9781 acgacggaaa tcataaatcc taatccccag gcgccgcgaa taacttggtg aagaaaggat
     9841 tgatcaaacc aacctgtaaa catttctacc aaccatacca ctagtgatag tccaataaaa
     9901 agaaagagaa tcgctttttt catttttcaa gctccttttt cacatctctt actaatttca
     9961 agccttctcg tatcaaccaa gacatgattc caaagcttgc aaacaactcc caaggaaaat
    10021 gatagaatcc ttcgtccaat cctgagaaca tgagataagt catgactcct gctactacta
    10081 aactcactgc gataatcatt ttatttctca tctcttcttc ctccatttca tactacaatt
    10141 atagtctttt gaaatcagag gagatagaag cttctgtcac taaaaaatat gacaaatgtc
    10201 ataaaaaatt ctgttcaaaa caagcaagat acactataca ataaaacaca attagataaa
    10261 tctaaggcaa cttcctcaaa agagatatca aaccccattc acactataat gtaaactaat
    10321 acttatttaa agtcaaaaga gcggaaattt ttatcgtaca aacatatata ttataggtaa
    10381 gacaaaaaac tcttcaatta ctttcttaaa aatttatagg agttataaaa tctattaaat
    10441 ttcaatgtgg atacctaaac tacagtattt attgaaaaga ctggagacaa aaagtatacg
    10501 ctgccaaaat gaattgctga aaatcaaaaa agagagaagc aaactgattc tctcttaatg
    10561 tatataatat ctagttataa aaatacacac tcacatatct ctgtaatgaa tcgggaagac
    10621 aggattcgaa cctgcgacac cttggtccca aaccaagtac tctaccaagc tgagctactt
    10681 cccgagttaa atagaaaaat gcaccctaga ggagtcgaac ctctaaccgc ctgattcgta
    10741 gtcaggtact ctatccagtt gagctaaggg tgctccatat tatgccgagg accggaatcg
    10801 aaccggtacg atcgttacca atcgcaggat tttaagtcct gtgcgtctgc cagttccgcc
    10861 accccggcct ctctaagcga acgacgggat tcgaacccgc gacccccacc ttggcaaggt
    10921 ggtgttctac cactgaacta cgttcgcact gttttcttct atctaaaaat gccggctaca
    10981 tgacttgaac acgcgaccct ctgattacaa atcagatgct ctaccaactg agctaagccg
    11041 gctcatttgt tatatcttaa tgcgggttaa gggacttgaa cccccacgcc gttaagcgcc
    11101 agatcctaaa tctggtgcgt ctgccaattc cgccaaaccc gcatatatga cccgtactgg
    11161 gctcgaacca gtgacccatt gattaaaagt caattgctct accaactgag ctaacgagtc
    11221 taaaataact tgcgttacct taaacggtcc cgacgggaat cgaacccgcg atcttcgccg
    11281 tgacagggcg acgtgataac cgctacacta cgggaccttt gggagttaac gggatcgaac
    11341 cgctgaccct ctgcttgtaa ggcagatgct ctcccagctg agctaaactc cctagagcta
    11401 agcgacttcc ctatctcaca gggggcaacc cccaactact tccggcgttc tagggcttaa
    11461 cttctgtgtt cggcatgggt acaggtgtat ctcctaggct atcgtcactt aactctgagt
    11521 aatacctact caaaatcgaa tatctattca attcaagaaa accgttcgct ttcatattct
    11581 cagttacttt ggataagtcc tcgagctatt agtattagtc cgctacatgt gtcgccacac
    11641 ttccacctct aacctatcta cctgatcatc tctcagggct cttactgata tataatcatg
    11701 ggaaatctca tcttgaggtg ggtttcacac ttagatgctt tcagcgttta tcccttccct
    11761 acatagctac ccagcgatgc ctttggcaag acaactggta caccagcggt aagtccactc
    11821 tggtcctctc gtactaggag cagatcctct caaatttcct acgcccgcga cggataggga
    11881 ccgaactgtc tcacgacgtt ctgaacccag ctcgcgtgcc gctttaatgg gcgaacagcc
    11941 caacccttgg gaccgactac agccccagga tgcgacgagc cgacatcgag gtgccaaacc
    12001 tccccgtcga tgtgaactct tgggggagat aagcctgtta tccccagggt agcttttatc
    12061 cgttgagcga tggcccttcc atacggaacc accggatcac taagcccgac tttcgtccct
    12121 gctcgagttg tagctctcgc agtcaagctc ccttatacct ttacactctg cgaatgattt
    12181 ccaaccattc tgagggaacc tttgggcgcc tccgttacct tttaggaggc gaccgcccca
    12241 gtcaaactgc ccgtcagaca ctgtctccga tagggatcac ctatctgggt tagagtggcc
    12301 ataacacaag ggtagtatcc caacagcgtc tccttcgaaa ctggcgtccc gatctcttag
    12361 actcctacct atcctgtaca tgtggtacag acactcaata tcaaactgca gtaaagctcc
    12421 atggggtctt tccgtcctgt cgcgggtaac ctgcatcttc acaggtacta aaatttcacc
    12481 gagtctctcg ttgagacagt gcccaaatca ttacgccttt cgtgcgggtc ggaacttacc
    12541 cgacaaggaa tttcgctacc ttaggaccgt tatagttacg gccgccgttt actggggctt
    12601 caattcatac cttcgcttac gctaagcact cctcttaacc ttccagcacc gggcaggcgt
    12661 caccccctat acatcatctt acgatttagc agagagctgt gtttttgata aacagttgct
    12721 tgggcctatt cactgcggct gacttaaagt cagcacccct tctcccgaag ttacggggtc
    12781 attttgccga gttccttaac gagagttctc tcgctcacct gaggctactc gcctcgacta
    12841 cctgtgtcgg tttgcggtac gggtagagta tgtttaaacg ctagaagctt ttcttggcag
    12901 tgtgacgtca ctaacttcgc tactaaactt cgctccccat cacagctcaa tgttacagat
    12961 ataagcattt gactcatatc acacctcact gcttagacag actcttccaa tcgtctgctt
    13021 tagttagcct actgcgtccc tccatcacta catactctag tacaggaata tcaacctgtt
    13081 gtccatcgga tacacctttc ggtctctcct taggtcccga ctaacccagg gcggacgagc
    13141 cttcccctgg aaaccttagt cttacggtgg acaggattct cacctgtctt tcgctactca
    13201 taccggcatt ctcacttcta tgcgttccag cactcctcac ggtatacctt catcacacat
    13261 agaacgctct cctaccatac ctataaaggt atccacagct tcggtaaatt gttttagccc
    13321 cggtacattt tcggcgcagg gtcactcgac tagtgagcta ttacgcactc tttgaatgaa
    13381 tagctgcttc taagctaaca tcctagttgt ctgtgcaacc ccacatcctt ttccacttaa
    13441 caattatttt gggaccttag ctggtggtct gggctgtttc cctttcgact acggatctta
    13501 gcactcgcag tctgactgcc gaccataatt cattggcatt cggagtttat ctgagattgg
    13561 taatccggga tggacccctc acccaaacag tgctctacct ccaagaatct ctaatgtcga
    13621 cgctagccct aaagctattt cggagagaac cagctatctc caagttcgtt tggaatttct
    13681 ccgctaccca caagtcatcc aagcactttt caacgtgccc tggttcggtc ctccagtgcg
    13741 tcttaccgca ccttcaacct gctcatgggt aggtcacatg gtttcgggtc tacgtcatga
    13801 tactaaggcg ccctattcag actcggtttc cctacggctc cgtctcttca acttaacctc
    13861 gcatcataac gtaactcgcc ggttcattct acaaaaggca cgctctcacc cattaacggg
    13921 ctcgaacttg ttgtaggcac acggtttcag gttctatttc actcccctcc cggggtgctt
    13981 ttcacctttc cctcacggta ctggttcact atcggtcact agggagtatt tagggttggg
    14041 agatggtcct cccagattcc gacgggattt cacgtgtccc gccgtactca ggatactgct
    14101 aggtacaaag actattttaa atacgaggct attactctct ttggctgatc ttcccaaatc
    14161 attcttctat aatctttgag tccacattgc agtcctacaa ccccgaagag taaactcttc
    14221 ggtttgccct cctgccgttt cgctcgccgc tactaaggca atcgcttttg ctttctcttc
    14281 ctgcagctac ttagatgttt cagttcactg cgtcttcctc ctcacatcct taacagatgt
    14341 gggtaacagg tactacctgt tgggttcccc cattcggaaa tccctggatc atcgcttact
    14401 tacagctacc caaggcatat cgtcgtttgt cacgtccttc gtcggctcct agtgccaagg
    14461 catccaccgt gcgcccttat taacttaacc ttattttctg acctttcagt cataaactct
    14521 tattaatact acagcgtttt cggtttattt tcttgttact atttgatata gatattcaat
    14581 tttcaatgtg cattacttgg tgatctctca ccaatggagc ctagcgggat cgaaccgctg
    14641 acctcctgcg tgcaaagcag gcgctctccc agctgagcta aggccccaca agacctctca
    14701 agactaaaca agaccaatgc gcagttcctt atccttagaa aggaggtgat ccagccgcac
    14761 cttccgatac ggctaccttg ttacgacttc accccaatca tctatcccac cttaggcggc
    14821 tggctcctta cggttacctc accgacttcg ggtgttacaa actctcgtgg tgtgacgggc
    14881 ggtgtgtaca aggcccggga acgtattcac cgcggcgtgc tgatccgcga ttactagcga
    14941 ttccgacttc atgtaggcga gttgcagcct acaatccgaa ctgagactgg ctttaagaga
    15001 ttagcttgcc gtcaccggct tgcgactcgt tgtaccagcc attgtagcac gtgtgtagcc
    15061 caggtcataa ggggcatgat gatttgacgt catccccacc ttcctccggt ttattaccgg
    15121 cagtctcgct agagtgccca actaaatgat ggcaactaac aataggggtt gcgctcgttg
    15181 cgggacttaa cccaacatct cacgacacga gctgacgaca accatgcacc acctgtcacc
    15241 tctgtcccga aggaaaactc tatctctaga gcggtcagag ggatgtcaag acctggtaag
    15301 gttcttcgcg ttgcttcgaa ttaaaccaca tgctccaccg cttgtgcggg cccccgtcaa
    15361 ttcctttgag tttcaacctt gcggtcgtac tccccaggcg gagtgcttaa tgcgttagct
    15421 acggcactaa accccggaaa gggtctaaca cctagcactc atcgtttaca gcgtggacta
    15481 ccagggtatc taatcctgtt tgctccccac gctttcgagc ctcagcgtca gttacaagcc
    15541 agagagccgc tttcgccacc ggtgttcctc catatatcta cgcatttcac cgctacacat
    15601 ggaattccac tctcccctct tgcactcaag ttaaacagtt tccaaagcct actatggtta
    15661 agccacagcc tttaacttca gacttatcta accgcctgcg ctcgctttac gcccaataaa
    15721 tccggacaac gctcgggacc tacgtattac cgcggctgct ggcacgtagt tagccgtccc
    15781 tttctggtaa gataccgtca cagtgtgaac tttccactct cacactcgtt cttctcttac
    15841 aacagagctt tacgatccga aaaccttctt cactcacgcg gcgttgctcg gtcagacttc
    15901 cgtccattgc cgaagattcc ctactgctgc ctcccgtagg agtctgggcc gtgtctcagt
    15961 cccagtgtgg ccgatcaccc tctcaggtcg gctatgtat
//
LOCUS       DAVAZV010000052        15099 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVAZV010000052 DAVAZV010000000
VERSION     DAVAZV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15099)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15099)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15099
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.052"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            244..582
                     /locus_tag="VQT46_001664"
     CDS             244..582
                     /locus_tag="VQT46_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HET2371649.1"
                     /translation="MTLTIHVYYKGDGDCAIKFAREMLESGLVAEIRCQKGNLKYEYF
                     LPIEKEGIILLIDQWINQEALDEHHQSNTMQKILDLRKKYHLQMQVERYIEDDSGMPE
                     SDKSFIDTGN"
     gene            772..2208
                     /locus_tag="VQT46_001665"
     CDS             772..2208
                     /locus_tag="VQT46_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET2371650.1"
                     /translation="MTTFKDGFLWGGAVAAHQLEGGWQEGGKGISVADVMTAGRHGVA
                     REITLGVLEGKYYPNHEAIDFYHRYKEDIALFAEMGFKCFRTSIAWTRIFPKGDELEP
                     NEEGLQFYDNLFDECLKNGIEPVITLSHFEMPYHLVTEYGGWKNRKLIDFFARFAEVV
                     FKRYKDKVKYWMTFNEINNQANYQEDFAPFTNSGIVYEEGDNREAIMYQAAHYELVAS
                     ARAVKIGHEINPDFQIGCMIAMCPIYPVTCNPKDILMAMKAMQKRYYFADVHVLGKYP
                     EHIFKYWERKGISVDFTDQDKEDLLGGTVDYIGFSYYMSFAIDSHRENNPYFDYLETE
                     DLVKNNYVKASEWEWQIDPEGLRYALNWFTDHYHLPLFIVENGFGAIDQVAADGMVHD
                     DYRIEYLGAHIREMKKAVVEDGVDLMGYTPWGCIDLVSAGTGEMRKRYGFIYVDKDDN
                     GKGSYNRSPKKSFGWYKKVILSNGESVE"
     gene            2260..2499
                     /locus_tag="VQT46_001666"
     CDS             2260..2499
                     /locus_tag="VQT46_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SemiSWEET family sugar transporter"
                     /protein_id="HET2371651.1"
                     /translation="MIGSIAAILTTFAFLPQVFRVVKTKDTGSIALGMYVMQVIGIAL
                     WLAHGIRIGDLPLILANSVSFLLSGIILFYKLKYK"
     gene            2629..2943
                     /locus_tag="VQT46_001667"
     CDS             2629..2943
                     /locus_tag="VQT46_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HET2371652.1"
                     /translation="MAKALIICAAGMSSSLMAQKTTEFLKGKGKDIVVDAISATEGGK
                     AIAAAAFDLYLVSPQTKMYFKQFEEAGSKAGKPVVQIPPQAYIPIPMGIEKMANLILE
                     NI"
     gene            3061..5040
                     /locus_tag="VQT46_001668"
     CDS             3061..5040
                     /locus_tag="VQT46_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET2371653.1"
                     /translation="MNVLNIKEKDILQFLIKNKERFVTSKELAEYLSCSDRTVRNVLK
                     LIEKTMIIQGVRLISKQGQGYQIFFENQGAYQEFRQTYELEEDYTKTAVSKGDDRLVF
                     ILNKLLFEQVPVLFDDLADELYVSRSTLSHDFRKIRVMLSEYNLSIESRANKGVYVSG
                     EERDKRRFIINYFLENQFFKTIHCYVKFNFFAQTVPLEEFARIVLDECQEANLKLSDF
                     VLQNLVVHIALSVIRLKSGFEIKNIDCQMTDDAIERKVAQRILSKVREVTNQEFPVQE
                     IDYITLHLLAKSQQCQKNQKNISEEVLKKSLFKTFQNLGLDDMYNFSSDFQLIEGLIT
                     HLMTLQVRLESRITLNNPLVDEIKQNYSDIFFMTREILANMDKFLEWTISDDEVAYVS
                     LHFLAAMERSKESTKFNILAICATGFGAAQMLRNRLETEFGKRVEVVDVIGYYELNQE
                     KLKGIDFIVSAVDLSNLYFQIPVFKVSVFLKSDEMEMIRKAMDQMQVSSYVQSSKINK
                     FENNSFRQYFSKENFLICTESDKVNLLEKMVESLSVGESNEFEQSLLYGIKQREELSS
                     VVFSEKIAVPHPIQPFGTEGKVSVAICKDSLLWDNQSSYVQLVFLLSPSIYGNEGLAT
                     VTKKIVSLTENDELQNQLISCNNFEDFISIFEKIK"
     gene            5050..5364
                     /locus_tag="VQT46_001669"
     CDS             5050..5364
                     /locus_tag="VQT46_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HET2371654.1"
                     /translation="MNQEELQVAAFEIILHSGNARSEIHEAFAKMREGSFDDAESKLN
                     QSNEIILEAHHAQTKLLQEYASGVEIKIEIIMVHAQDHLMTTMTLLEVAKEMLALYKK
                     VN"
     gene            5395..5901
                     /locus_tag="VQT46_001670"
     CDS             5395..5901
                     /locus_tag="VQT46_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371655.1"
                     /translation="MDKKERQKIEQQRREMALTNTFFNRYLLLRYSIALFFFGNIYWL
                     LNQFINPSPIIIFPIMLIVFSILATVEQFKLYGNRKEKLGITLMFVRIQILISIGLLV
                     LTWTSWFKNLFPIFENNQVARLFVFVVLLLGLVLSLLDIRRIKKIYKRTDKAYQQFVQ
                     LEKNSLSL"
     gene            5981..7327
                     /gene="celB"
                     /locus_tag="VQT46_001671"
     CDS             5981..7327
                     /gene="celB"
                     /locus_tag="VQT46_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HET2371656.1"
                     /translation="MDQQNGLFGFLENHVMGPMGKLAQFKVVRAITAAGMAAVPFTIV
                     GSMFLVFSILPQAFSFWPIVADIFSASFDKFTSLYMVANYATMGSLSLYFVLSLAYEL
                     TKIYAEEEELNMNPLNGALLALMAFVMTVPQIIFDGGMMKTVTSLKEGAVIADGWAMG
                     NGVARFGTTGIFTAIIMAIVTVLIYRMCVKHNWVIKMPEAVPEGVSRGFTALVPGFVV
                     AFVVIFINGLLVAMGTDIFKVIAIPFGFVSNLTNSWIGLMIIYLLTQLLWIVGIHGAN
                     IVFAFVSPIALANMAENAAGGHFAVAGEFSNMFVIAGGSGATLGLCLYIAFASKSEQL
                     KAIGRASVVPALFNINEPLIFGLPIIYNPALAIPFILAPMVTATIYYVANSLNFIKPI
                     IAQVPWPTPVGIGAFLGTADLRAVLVALVCAFAAFLVYLPFIRVYDQKLVKEEQGI"
     gene            7707..7883
                     /locus_tag="VQT46_001672"
     CDS             7707..7883
                     /locus_tag="VQT46_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371657.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            8293..10506
                     /locus_tag="VQT46_001673"
     CDS             8293..10506
                     /locus_tag="VQT46_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HET2371658.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSQTGSFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHFFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(10728..11204)
                     /locus_tag="VQT46_001674"
     CDS             complement(10728..11204)
                     /locus_tag="VQT46_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET2371659.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            11427..14627
                     /locus_tag="VQT46_001675"
     CDS             11427..14627
                     /locus_tag="VQT46_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET2371660.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSADASTRVIEAKDGA
                     ITISSHEKLRAAVHRMVPIEAKKKYKLRFKIKTDHKVGIAKVRIIEESDKDKRLWNSA
                     TTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQPSEDYQTD
                     KQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKEV
                     KKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSIS
                     SQADRTYLWEKFSNYKMSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSMEW
                     MHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDPE
                     HFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGFY
                     QDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAPL
                     LVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQS
                     DSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRTSYLSAFNKMDKTAMYNAEKGFGFG
                     LSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTET
                     DAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFLG
                     SNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDSK
                     KNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYML
                     IPNVGRATFNQMIKELERSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVLK
                     RGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKNH
                     SDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            15007..15099
                     /locus_tag="VQT46_001676"
                     /pseudo
     CDS             15007..15099
                     /locus_tag="VQT46_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005576373.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         5031 a         2205 c         3096 g         4767 t
ORIGIN      
        1 ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct tttatgaggc
       61 tcttttgtct tgttcttgtt tcaattgact ataaatcgct ataagaaaaa atcattttat
      121 tggtataaag aagtgattga aagtaatggc gaaacgttag ataattagtt cataaaaaac
      181 aagtttagat cctcatctaa acttgttttt ttaaaattga aggatgattt tggaggatat
      241 gagatgacat tgactattca tgtatattat aaaggcgatg gagattgtgc aataaagttt
      301 gcaagagaaa tgcttgaatc tgggcttgtc gcagaaatta gatgtcaaaa aggtaatttg
      361 aaatacgaat attttttacc aattgaaaaa gagggaatta ttctccttat tgatcagtgg
      421 ataaatcaag aagctttaga tgaacatcat caatcaaata caatgcagaa aatcttagat
      481 ttaagaaaaa aatatcactt gcagatgcaa gttgaacgtt atatagaaga tgattctggg
      541 atgccagaaa gcgataagtc gtttatagac acagggaatt agaattattg tgagagtttt
      601 tgtagtttga aagtattgaa aatcgtaaag atatcattac gagaatacaa gaagatattg
      661 ttctatttcc attaaaaatt acttctttcc ttaataataa ggaaaaagaa tacgttttca
      721 tcttttggtt tgaggtttat aataagaata tcaaagtcag gaggaaaaaa gatgactact
      781 tttaaagatg gatttttatg gggtggtgct gttgctgctc atcaacttga aggcggatgg
      841 caagaaggtg gcaaaggaat tagtgttgct gatgttatga ctgctggtcg ccatggagta
      901 gctcgtgaaa ttactttggg agttttagag ggtaaatatt atccaaatca tgaggcgata
      961 gatttttatc atcgttataa agaagacata gcactttttg ctgaaatggg attcaagtgc
     1021 ttccgtacct ctattgcatg gacacgtatc tttccaaaag gtgatgagtt agagccgaat
     1081 gaagaaggat tacagtttta tgataatctt tttgatgaat gcttaaagaa tggtattgaa
     1141 cctgtcatca ctctatctca ttttgaaatg ccttatcact tagtgaccga atatggtggt
     1201 tggaaaaata ggaaattgat tgatttcttt gctcgttttg cagaagtcgt atttaaacgt
     1261 tacaaagata aggttaaata ttggatgact ttcaatgaaa tcaataatca agcgaattat
     1321 caggaagatt ttgcaccatt tactaactca ggtattgtat atgaggaagg tgataataga
     1381 gaagcaatta tgtatcaagc agcacattac gaattagttg cttctgcacg agctgtaaaa
     1441 attggtcatg agattaatcc agattttcaa ataggttgta tgattgcgat gtgtccaatt
     1501 tatccagtta cttgcaatcc taaggatatc ttaatggcaa tgaaagctat gcagaagcgt
     1561 tattattttg ctgatgtgca tgttttaggt aaatatcctg agcatatttt caagtattgg
     1621 gaacgaaaag gtatttcagt tgattttact gaccaggata aagaagattt acttggtggg
     1681 actgtagatt acattggttt cagttactat atgtcctttg ctatagactc tcatcgtgaa
     1741 aataatcctt attttgatta tcttgaaaca gaagatttag tgaaaaataa ttatgttaag
     1801 gcttctgaat gggagtggca aattgatcca gaaggtttac gttatgcgtt aaattggttt
     1861 acagaccact atcacttacc actctttatt gttgaaaatg gttttggagc tatagatcaa
     1921 gttgcagcag atggtatggt acatgatgat tatagaattg aatatctagg tgcccatatt
     1981 cgtgaaatga aaaaggctgt agttgaagat ggtgttgatt taatgggtta tactccatgg
     2041 ggatgtattg atttggtttc agctggtacc ggtgaaatgc ggaaacgtta tggctttatt
     2101 tatgtagata aagatgacaa tgggaaggga agttataatc gttccccgaa aaaatctttt
     2161 ggctggtata agaaagttat tttatctaac ggtgaatcag tagaatagta taaacaaact
     2221 gagattattc tcagtttgtt tagcatattg aggagacata tgattggaag tattgcagca
     2281 attttaacaa catttgcatt tttaccacaa gtttttcgtg tagttaagac aaaggacaca
     2341 ggatctattg ctctaggtat gtatgttatg caagttattg gtattgcatt gtggcttgct
     2401 catggtattc gtataggaga cttgcctttg attttagcaa atagtgtttc atttctactc
     2461 tcaggaataa ttttatttta taaattgaag tataaataat ttttttccat atcatttagg
     2521 aaaatgaggg aattgtcatt gaaaacgctt tattttataa taaaaataga taacaaataa
     2581 gccaacttag cacagctttg attggattta agaaaaggag aaaatattat ggcaaaagct
     2641 ttaattattt gtgcagcagg aatgtcttca tcacttatgg cacagaaaac aacagagttt
     2701 ctaaaaggaa aagggaaaga tattgtagtt gatgctatta gtgctactga aggagggaaa
     2761 gctatcgcag cagcagcttt tgatttgtat cttgtcagtc ctcaaacaaa aatgtacttt
     2821 aagcaatttg aagaggctgg ttctaaagca ggaaaaccag ttgtacaaat acctcctcaa
     2881 gcctatattc ctattccaat gggaattgaa aaaatggcta atttgattct tgagaatatt
     2941 tgatgaacac atgaaatgtc aataaatatt taagttaaga taaattgttt tgagtttgat
     3001 ataaattgat ttaagtgtat aatatgcttc aatatatgaa aacatacgtt ttaggaggga
     3061 atgaatgtgt taaacattaa agagaaagat atccttcaat ttttaataaa aaataaggaa
     3121 cgttttgtta caagcaaaga actggcagaa tatttatcct gttcagatag aactgtccgt
     3181 aatgtactga aattaattga gaagacaatg attattcaag gagtccggtt gatttcaaaa
     3241 caaggtcaag ggtatcaaat attttttgag aatcaaggcg cttaccagga gtttagacaa
     3301 acttatgaac tggaagaaga ctatacgaaa actgcggttt caaaaggtga tgatcgttta
     3361 gtatttatct taaataaatt attatttgag caagttccag ttctttttga tgatttagct
     3421 gatgaacttt acgttagtcg ttcaacatta tctcatgatt tcagaaagat acgagtgatg
     3481 ttatcagagt ataatttgtc cattgagagt agggcgaata aaggagttta tgtctcaggc
     3541 gaggaacgtg ataaacgacg ttttatcata aattatttcc tagagaatca attttttaaa
     3601 acaatacatt gctatgtaaa atttaacttt tttgctcaaa ctgttccatt agaagaattt
     3661 gctagaattg ttttggatga atgccaagag gccaacctaa aactatctga ttttgtacta
     3721 cagaatttag tagttcacat agcattgtct gtgattcgtt taaaatccgg atttgaaata
     3781 aaaaatatag actgtcagat gactgatgat gcaatagaga gaaaggttgc tcaaagaatt
     3841 ctttctaaag taagagaagt aacaaatcag gaatttccag ttcaggaaat agactacatt
     3901 actttgcatt tgttagctaa gagtcaacaa tgtcaaaaaa atcagaagaa tatttctgaa
     3961 gaagttttaa aaaaatcttt atttaaaaca tttcagaatt taggattaga tgatatgtat
     4021 aacttttctt cagatttcca actaattgaa ggattgataa ctcatctaat gacactacaa
     4081 gtacgtttag aaagccggat taccttaaat aaccctttgg tagatgaaat taaacagaat
     4141 tatagtgata tattctttat gactagagaa attcttgcaa atatggacaa gttcttggag
     4201 tggacaatat cagatgatga agtagcatat gtaagtcttc actttttagc tgctatggaa
     4261 cgtagcaaag agagtactaa gtttaatatt cttgctattt gtgcaacagg atttggtgca
     4321 gcccaaatgt taagaaatcg tttggaaacg gagtttggga agcgagtaga agttgttgat
     4381 gtaataggct attatgaatt gaatcaagaa aaacttaaag gaatagattt tatagtgtca
     4441 gctgttgatt tatcaaatct atattttcaa attccagttt ttaaagttag tgtgtttctt
     4501 aagagtgatg agatggaaat gattagaaaa gctatggatc agatgcaagt ttctagttat
     4561 gtacaatcat caaagattaa taaatttgaa aacaacagct ttagacagta ttttagtaaa
     4621 gaaaattttt taatatgtac tgaatcagac aaggtaaatt tacttgaaaa gatggttgag
     4681 agtttatctg ttggtgaatc aaatgagttt gaacaatctt tactttatgg aattaaacag
     4741 cgcgaagaat taagttcagt tgttttttct gaaaaaattg cagttccgca tcctattcag
     4801 ccctttggta cagagggaaa ggtttcggtt gcaatctgta aagattcgtt actctgggat
     4861 aatcaaagtt catatgtcca gctagtattt cttctatctc catcaatata tgggaacgaa
     4921 ggtttggcaa ctgtgactaa aaagatagtc tctctgacag agaatgatga gttgcaaaat
     4981 cagctaatat cttgcaataa ctttgaagat tttattagca tatttgagaa gataaaatag
     5041 gaggttcata tgaatcaaga ggaactgcag gttgcagcat ttgaaattat cctgcattcg
     5101 ggaaatgcaa ggtcagaaat acatgaagca tttgcaaaaa tgagagaagg tagttttgat
     5161 gatgcagaaa gtaaattaaa tcaatcaaat gagataattc ttgaagcgca tcatgcacaa
     5221 accaaactct tgcaagaata cgcaagtgga gtggaaatta aaattgaaat tatcatggta
     5281 catgctcaag atcatttaat gaccactatg acattattag aagtagcaaa ggaaatgtta
     5341 gctctttata agaaagttaa ctaaatatgt gttgttatat aaggaggaaa tgatatggat
     5401 aaaaaagaac gacaaaagat tgaacaacaa cgtcgagaga tggctctaac taatactttt
     5461 tttaatcgat atcttcttct acgttattca atagcactct tcttttttgg gaatatttat
     5521 tggcttttga atcagtttat taatccctcg cctattatta ttttccccat tatgctcata
     5581 gtattttcta ttttagcaac tgttgaacaa tttaaactct atggaaatag gaaagaaaag
     5641 ttgggaataa cactaatgtt tgttagaata caaatactta tttcaatagg attacttgtt
     5701 ttaacttgga caagttggtt taagaatctt tttccgattt ttgaaaataa ccaagtagca
     5761 cgtttatttg tttttgtagt tcttctatta ggtttagttc tgagtttgtt agacattaga
     5821 agaattaaaa aaatttataa acgaacagat aaggcttatc aacaatttgt ccaattggaa
     5881 aagaactcac ttagtttata atcctgatct agtataattt gtatttgaaa ctagtcttta
     5941 gaaagtaaaa attattatgt tttattaagg aggtctattt atggatcaac aaaacgggtt
     6001 gtttggtttt cttgaaaacc atgttatggg accaatgggc aaacttgctc agtttaaagt
     6061 agtgcgtgct atcacggctg caggtatggc tgctgtacca tttactattg taggatcaat
     6121 gtttttggta ttcagtattt tgccacaagc tttctcattt tggccaattg tggcagatat
     6181 tttctctgct tcatttgata aattcacatc actttacatg gttgcaaact atgcgactat
     6241 gggttctcta tctctttatt tcgttctatc acttgcatat gaattgacaa aaatttatgc
     6301 agaggaagaa gaactcaata tgaatcctct taatggtgcc ttgctcgcct tgatggcttt
     6361 tgtcatgaca gtaccgcaaa tcatttttga tggtggaatg atgaagactg tgacaagtct
     6421 aaaagaaggt gcagtaattg cagatggatg ggcaatggga aatggagtcg cacgttttgg
     6481 gacaacaggg atttttaccg caatcattat ggcaattgtg actgttctta tttatcgtat
     6541 gtgtgttaaa cataattggg ttattaaaat gcctgaagct gttccagaag gagtttctcg
     6601 tggatttacc gctttggttc cgggatttgt tgttgcattt gttgttatct ttatcaacgg
     6661 tcttcttgta gcaatgggaa cagatatttt taaagtcatt gcaattccat ttggttttgt
     6721 atccaatctg actaattcgt ggattggttt aatgattatt tatctattga ctcaactact
     6781 ttggattgta ggtatccacg gtgcgaacat tgtttttgca tttgttagtc caattgctct
     6841 tgctaacatg gctgaaaatg ctgctggcgg gcacttcgct gttgcaggtg aattttctaa
     6901 tatgtttgta attgcaggtg gttctggtgc aactttagga ctatgtttat atattgcttt
     6961 tgcctctaaa tctgaacagc ttaaagcaat aggacgagca tctgtagttc cagccttatt
     7021 taatattaat gaaccattaa tttttggatt acctattatc tataatccag ccttggctat
     7081 accatttatt ttagcaccaa tggttactgc tactatttat tacgtagcga attctctaaa
     7141 ctttattaag ccaattatcg cacaggttcc atggccaact ccagtaggga ttggagcttt
     7201 cttagggaca gcagatcttc gagctgtatt agttgctcta gtatgtgcat ttgcagcatt
     7261 cttagtctat cttccattca tccgtgtata tgatcaaaaa ttggtgaaag aagagcaagg
     7321 tatctaataa gtaaaaaagt atactcgatg atagaatcca tatagtttaa ataatgagtg
     7381 ttaatattag cagtgaagag gtctttttaa gatattcttc tctgcttttt catatttttt
     7441 cgctatgtag ggtatgaagc aaaatagaaa gtagttcgaa tagttgataa acaggaaact
     7501 gctgttattt aaaaaaaaca ataaagtaaa gtatgttatc gtagaatacg atacaatagt
     7561 aaaaaagcaa aaagaatgcg ttttatattt gggtttgagg tttataaaat aggataagcg
     7621 tgctgaaaac ttagatatga caaacaaaat aaaattttta aaagctacat agaaacatgg
     7681 tataatgtat ctaaaggagg tagcatatgt ccttagatat agataaagaa aagatgacaa
     7741 tcatgggaat agcttttgaa aacagatccg tttttaagag tgtttggtat gctttaagta
     7801 caaatatgat tgaaggatgg cgacctacgg ttagtgatgt tgaaaaatta cgagatgaag
     7861 ctcttgctct ggggatgact taatgaagcg caactgttat gagtcttatg actatgttga
     7921 tccggataat ttatataccg atccgggttc ttcagttcta agaaataagc aggaaggaaa
     7981 aaagcacgcg agcttgaata tcgtatgatt gctagtaaga gtttgaaatt atttatcaat
     8041 cctatcttag ttaatagttt aaaagtagtt tgtttcacaa ctgcataagc ttagaaaagt
     8101 tgaaaagtga taactcttta ataaactctt ggtttgttaa aagatatttt gtccactaca
     8161 ttttttcaat tgactattat ttgtcataga tataacagat agaacagata gaacattgca
     8221 ttcagaataa tgaaaaacgc atcaaaaatg gtgcgttctg tttttatgct accataaaag
     8281 gaggaaaaca aattgaaaat ttttaaggga gagttttatc gaatctctgt attaacagac
     8341 aagctagtaa ggttagaata ctctcaaact ggaagttttg aggatagaac gacacaactt
     8401 atctataata gagattttgg ccaagtttcg ttagattata tcgagacatc aaacgtacta
     8461 gatattatga cggactattt tcatctgcac tttaataaag gagaatttaa cgccgaaaat
     8521 ttatttatag aattaaaagg aaattttgcc gtatatggta gtcgctggta ttttggtgaa
     8581 tctattgaaa cgttaaaagg aacagctcgg actctggata aggcagatgg agcaatctcg
     8641 ttagaagatg gaattattag ccgaaatggt atagccttat tggatgattc tcaaggattt
     8701 atttgggatg aacaatctgg ttatattgag agagaaaatc aaattgacct gtatttcttt
     8761 gcctatgggc atgattatag aggagcaatc agagactttt accatttgac tggttcaaca
     8821 cccttgttgc caagatatgc tttaggcaat tggtggagta gatattggcc ttatacgtcg
     8881 gatgaatact tggatttaat agacagattt gaaacagaga aaattccatt atctatcggt
     8941 gtgttagata tggattggca tataactgac attccagctc gttttggaag tggctggaca
     9001 ggatatagtt ggaatagaaa cttaatacca aatccagaac agttattgca acaacttcat
     9061 gatagaaagt taaaactctc cttaaatgtc catcctgctg atgggatacg ggcttatgaa
     9121 gaagcttatc ctcaaatcgc aaaacggttg gggttaaatg tagaactaga agaacctgct
     9181 atttttgatt tttttaatcc ctcttttagg gaagcctact ttaaagatgt tcattatgag
     9241 ctagaaaagc agggagtaga tttttggtgg attgactggc aacaagggac acaaggtatg
     9301 ctagatccac tttggctttt aaaccattat cactatcagg atagttgtaa aaatgcagaa
     9361 ggtggtttga ttttatcaag atatgcaggt cctggtagtc accgctaccc tgttggtttt
     9421 tcaggggata ctattattag ttggaattcc ttaaggtttc aaccctattt tacagcgaca
     9481 gcatctaata tcggttatag ttggtggagt catgatatcg gtggacatat gttgggggat
     9541 tatgacgaag agctacaaac tagatggcta cagtttggtg tttttagtcc gattactcga
     9601 ttacatagtt ctagaagtcc ttttaatagt aaagaacctt ggttcttttc agaaacaaca
     9661 tctaagatta tgaagaaata ccttcgtttg agacatcaga tgattcccta tctatatacc
     9721 atgaatgtaa agacacatga ggaaggtgcc ccattaatca gtccaatcta ttatttctat
     9781 ccagagaatg atgagagcta taatgttcca aaccaatact tttttggaac agaactgatg
     9841 gtggctccca ttgtagaaaa gatggatttg acattccaat ctgcaaaagt agatgtatgg
     9901 ttccctgaag gtgaatggta tgacttcttt tcagagaaaa aatacacagg tggtgtgaag
     9961 ttaagtgttt atagggacat ctcgactacg cctgtgtttg caaaaagtgg tgcaatcatt
    10021 cccttggttg gttctgagat aggtatgggt gttgatttac ctgaggttgt agattggtat
    10081 gtattcccag ggaaacaaca tttttttgaa atgcttgaag atcaaaatgg tcaaagatat
    10141 aaaacaagat tatcaatcga ttgggaaatg ggaatggtag agttagcatt acaaggagat
    10201 tctagtatcg ttccaagcaa tagaaaacat agaattcatt ttaaaggaac gaatgtgtct
    10261 ataattgaat tgccaaataa gaatgataca gctaaatttg aatggaaaga taataaaagg
    10321 acatctttaa atgacgaagt ttttagacta ctaaagacag cttctcttcc atatgaatta
    10381 aaagatagat tgttaaatca attcatcaat gcgaaaaact ctcatgactt aatgaatatc
    10441 ttgcatcatc aggataagga attgagaggg cgtttgttgg aaatgatatt tactagccaa
    10501 aactaattga aataattaga aagtcatttg tttagtgtat atgaagattc tgtatggtat
    10561 tcgttatcac tggtcacatt gaaaatgtga aataagcacc tacaacatag actttacaac
    10621 acttcatgtt tcatatcatg gggtgttttt ctatttaagt caaagcccat caaaaaatct
    10681 cactattcat caggttaaag gaaacctaat catagtgaga ttgtgaatta tagtagagtt
    10741 tgtatcgcct cttcaatttg ttttgggtct gtttttgaag aaaagcgttc aaagacttgc
    10801 ccatctcgac cgatgagaaa cttagcgaaa ttccattcga ttcgttttcc tagtgggccg
    10861 gatttctggt cttttaacca gacatagaga gggtctgctt ccttaccgtt gaccttaatc
    10921 ttggcaaaac gtgggaaggt ggtttgaaaa tgtaggctac agaaggcgtt gatttcctct
    10981 gcgctgccgg gtgcttgtcc cataaactga ttgcaaggga aatccaatat ttcgaagccc
    11041 tgatcttgat agcgttcata gagttcttga agtccctggt actggggcgt taaaccacat
    11101 ccagtagcag tgttgacaat caagagaact ttgccacgat agctatccaa gggagttgct
    11161 tggttgtttt ggttcaaaac ggaaaaatca taaagtgaag tcatgagggc ctcttttctt
    11221 tttctacatt gtaacagttt ttactttttt cgtcgagtcg gatggaagat attgttgaag
    11281 aataagcctt caatatgata gaaaccgttt acaaataact ttaaaaatgg tatgatttaa
    11341 ttaaaccggt ttacttagtt gctataaatc tctaatttga gatttagttc ctattgattt
    11401 tacaatatgt ttattggagt gtatacatgc aaacaaaaac aaagaagctc attgtgagtt
    11461 tgtcttcact tgttttatca ggatttttat taaaccatta tatgacagtt ggagcggaag
    11521 aaacgactac gaataccatt cagcaaagcc agaaggaagt tcagtatcag caaagggata
    11581 caaaaaattt agttgaaaat ggtgattttg gtcagacgga ggacggaagc agtccgtgga
    11641 caggaagcaa agctcagggg tggtcagctt gggtagacca gaagaatagt gcagatgcct
    11701 caactcgagt cattgaggct aaggatgggg ctatcactat ctcaagccat gagaaattaa
    11761 gggcagcggt tcaccgtatg gttcctattg aagctaagaa aaagtataaa ctgcgtttca
    11821 agattaaaac agatcataaa gtcgggattg ccaaagttcg tatcattgag gaaagtgata
    11881 aggacaagcg attgtggaat tctgcaacga cgtcaggaac aaaggactgg cagaccattg
    11941 aagcagacta tagcccgact ttagatgttg ataaaatcaa gctggagtta ttctatgaaa
    12001 caggaactgg gactgtttcc tttaaggata ttgagctggt agaggtagca gaccagcctt
    12061 ctgaggacta tcaaacagat aaacagcttg aggaaaagat tgatttacca attggaaaaa
    12121 aacatgtttt ttctcttgcg gactatactt ataaggtaga aaatcctgac gttgcttcag
    12181 tcaaaaatgg aattttagaa cctcttaagg aagggacaac caatgtcatt gtcagtaaag
    12241 atggcaagga agtgaaaaag attcctttga agattctagc ctctgttaag gatgcataca
    12301 cagaccgttt ggatgactgg aatggcatca tcgctgggaa tcaatactat gattctaaaa
    12361 atgaacagat ggccaaatta aaccaggaat tggaaggaaa ggtagctgat agcctatcta
    12421 gtatttcaag tcaggcggac cgcacctatt tgtgggaaaa attttcaaat tataaaatgt
    12481 ctgcaaatct gactgccact tatcggaaat tggaggagat ggccaagcaa gtgaccaatc
    12541 cttcttctcg ttattatcaa gatgaaactg tcgttcgaac agtcagggat tccatggaat
    12601 ggatgcataa acatgtctac aatagtgaaa agagcattgt tgggaactgg tgggattatg
    12661 aaatcggtac acctcgtgcc atcaacaata ccttgtctct gatgaaagaa tacttctctg
    12721 atgaggaaat taaaaaatat acagatgtga ttgaaaaatt tgtaccagat cccgaacatt
    12781 tccgaaagac gactgataac ccatttaagg ctctaggtgg aaacttagtt gatatgggaa
    12841 gagtaaaagt aatagctggt ttactgcgta aggatgatca agaaatttct tctaccattc
    12901 gctcgattga gcaagtgttc aagttggtag accaaggtga aggtttttat caagatggat
    12961 cctatatcga ccataccaat gttgcctata cgggtgctta tgggaatgtt ttgattgatg
    13021 gcctgtctca actgttgcca gtcattcaaa agaccaagaa tccaatcgat aaagataaaa
    13081 tgcaaaccat gtaccactgg attgataaat cgtttgctcc tttgctggtg aatggagagc
    13141 tgatggatat gagtcgtgga cgctcgatca gtcgtgcaaa tagcgagggg cacgtggccg
    13201 cagtagaagt actaagaggg attcaccgaa tagcggatat gtctgaagga gaaaccaaac
    13261 aacgtttgca gagtcttgtg aagaccattg ttcaatcgga tagttattat gatgtcttta
    13321 agaatttgaa gacttataag gatatcagtt tgatgcaatc cttgttaagt gatgcaggag
    13381 tcgcaagtgt tccaagaaca agttacctat ctgcctttaa caagatggat aaaacagcca
    13441 tgtacaatgc agagaaaggg tttggatttg gcttgtcact cttttccagt cgtaccttga
    13501 attacgaaca catgaacaag gaaaataaac gtggttggta tacgagtgat gggatgttct
    13561 atctttacaa tggcgatttg agtcactata gcgatggcta ctggccaaca gttaatccat
    13621 ataagatgcc tggtacaaca gagacggatg ctaagagagc ggatagcgat acaggtaaag
    13681 ttttaccgtc tgctttcgtt ggaacgagca aactagatga tgccaatgcg acagcaacca
    13741 tggatttcac caactggaat caaacattga ctgctcataa gagctggttt atgctaaagg
    13801 ataagatcgc ctttttagga agcaatatcc aaaacacttc aacagatact gctgcaacta
    13861 caattgacca gagaaaactg gaatcaagta atccatataa agtctatgtc aatgataaag
    13921 aagcctccct tacagaacaa gaaaaggatt atcctgaaac ccaaagtgtc tttttagaat
    13981 catccgattc gaaaaagaat attggttact ttttctttaa gaagagttca atcagtatga
    14041 gtaaggcttt gcaaaaggga gcctggaagg atatcaatga aggacagtca gacaaggaag
    14101 ttgaaaatga atttcttacg attagtcagg ctcataagca aaatggagat tcttatggct
    14161 atatgctcat ccctaacgtg ggtcgtgcca ccttcaatca aatgataaaa gagttagaaa
    14221 gaagcctcat cgaaaataac gaaacccttc agtctgttta tgatgccaaa caaggagttt
    14281 ggggcattgt gaaatatgat gattctgtct ctactatttc caaccaattc caagttttga
    14341 aacgtggagt ctataccatt cgaaaagaag gggatgaata taagattgcc tactataatc
    14401 ctgaaaccca ggaatcagct ccagatcagg aagtctttaa aaagctagag caagcagctc
    14461 agccacaagt acagaattca aaagaaaagg aaaaatctga agaggaaaag aaccattcgg
    14521 atcaaaagaa tctccctcag acaggagaag gtcagtcaat cttggcaagt ctagggttct
    14581 tgctacttgg ggcgttttat ttattccgta gaggaaagaa caactaattt gttcatcatc
    14641 tagatgaatt acatgaaact gtggaaaata gaaaaaatcc gaagaaggcc aaatatcttc
    14701 ggatttttct tttaaaaaag gataagttga tacttatcct ttttacttca ttatgtgact
    14761 atagcgtttt gaaactagaa taggacatca taactgctaa aagatttcta taaattcatt
    14821 tgattttcct aatcaattta ttcgtatcct atttcactct actatattag tccgtctcgc
    14881 acctcacgga gcgagacaaa acaaccaccc gctatgcggg tgcgcgtcga aggttatacc
    14941 aaaaaaactc caaacgcgat acaataaagg tgttcaatcc acttgtaaag cgaaaggaga
    15001 aaaaatatgg cacaaaaggc tcatagttta tctcacacaa agtggaggtg ttctatcaca
    15061 ttgtgttcac ccctaagtat agacgaaaag tcatctata
//
LOCUS       DAVAZV010000053        15003 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVAZV010000053 DAVAZV010000000
VERSION     DAVAZV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15003
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.053"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            165..866
                     /locus_tag="VQT46_001677"
     CDS             165..866
                     /locus_tag="VQT46_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HET2371661.1"
                     /translation="MYSGFTHYKYYRAEIIRKVQEPEFWKEVNLSDLEKIRLAIRDLL
                     QFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKTHLDEESISKL
                     YHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRESANRIFSK
                     FLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQLLFQHQLPVLRNI
                     VQIIELINNRAGEAA"
     gene            complement(1266..2612)
                     /locus_tag="VQT46_001678"
                     /pseudo
     CDS             complement(1266..2612)
                     /locus_tag="VQT46_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
     gene            2674..2868
                     /locus_tag="VQT46_001679"
     CDS             2674..2868
                     /locus_tag="VQT46_001679"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371662.1"
                     /translation="MSSKKHPLGEKRNHTGSKLRQGFWMVFRLGVNNWGFKEIENKKP
                     SKNSIAGENEIILNENQRAN"
     gene            2846..3046
                     /locus_tag="VQT46_001680"
     CDS             2846..3046
                     /locus_tag="VQT46_001680"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371663.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDKTDEVSSKHGFEVVDETDEVS
                     NHTYGKATLTRIEEIFEEYKSS"
     gene            complement(3126..3571)
                     /locus_tag="VQT46_001681"
                     /pseudo
     CDS             complement(3126..3571)
                     /locus_tag="VQT46_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3579..3722
                     /locus_tag="VQT46_001682"
     CDS             3579..3722
                     /locus_tag="VQT46_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371664.1"
                     /translation="MAERFWENLSIILADRNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            3815..4402
                     /locus_tag="VQT46_001683"
     CDS             3815..4402
                     /locus_tag="VQT46_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2371665.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCSDELTILQILYGASLIS
                     FLWMYGQRKQVIKVNMKTRIQWLGIGFVSLLIISLCFSLIHAQESTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTIIAWCLYV
                     SLGMFLGLVRYKLDLWGSMGLHLVWNLLVYSLLLF"
     gene            4801..5610
                     /locus_tag="VQT46_001684"
     CDS             4801..5610
                     /locus_tag="VQT46_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2371666.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNNYSCKALC
                     ECLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIREKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKVSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWNSLLLNENCLVIGASVSGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTNHLSYGNRISPQFPILLITDCLFSHYLESPERQYYYNQTIIHKEE"
     gene            5615..6316
                     /locus_tag="VQT46_001685"
     CDS             5615..6316
                     /locus_tag="VQT46_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2371667.1"
                     /translation="MSQIWTKEKFISQVHGGVIVSCQALPGEPLYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVINEFIKKIKEKYPNQLLMADVSNFDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            6341..7258
                     /locus_tag="VQT46_001686"
     CDS             6341..7258
                     /locus_tag="VQT46_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HET2371668.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQERVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHVACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAAPNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            7286..8827
                     /locus_tag="VQT46_001687"
     CDS             7286..8827
                     /locus_tag="VQT46_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HET2371669.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGNSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGAVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLMANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNAGSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDDRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDIPEIKADSS
                     WEVRH"
     gene            8846..9304
                     /locus_tag="VQT46_001688"
     CDS             8846..9304
                     /locus_tag="VQT46_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2371670.1"
                     /translation="MIISEQSDFRRYASINKHFSKVCDFLENTNLTDLVDGKVDIDGE
                     NVFANCMIYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDEPVKKLVIKVLNEEK"
     gene            9306..11528
                     /locus_tag="VQT46_001689"
     CDS             9306..11528
                     /locus_tag="VQT46_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HET2371671.1"
                     /translation="MKKNIKQYVTLGTAVVLSAFVANSVAAQETETSEVSTPELVQPV
                     APTTPISEVQPKSGNSSEVTVQPRTVETTVKDPSSATEETPVLEKNNVTLTGGGENVT
                     NELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNHLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPRDVGGRDLQISGGATYIDSVIVEKNNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLKKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFKNNKKTEYRNGTHVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSTDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            11568..12677
                     /locus_tag="VQT46_001690"
     CDS             11568..12677
                     /locus_tag="VQT46_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2371672.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEYEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            12834..13724
                     /locus_tag="VQT46_001691"
     CDS             12834..13724
                     /locus_tag="VQT46_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET2371673.1"
                     /translation="MKIIGIDIGGTTIKADLYNEFGTSLNQFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYILNHSIDGVGISTAGVVNANTGEIIYTGYTIPGYIGVNFTFEIEKRF
                     GLSTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRAGDKVAKETFEIFVE
                     NLTKGLLTITYLLNPEILILGGGILAKKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            13749..14072
                     /locus_tag="VQT46_001692"
     CDS             13749..14072
                     /locus_tag="VQT46_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371674.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENYEKIQYISSSRRGEFVEKIIGRVV
                     EKYGY"
     gene            14062..>15003
                     /locus_tag="VQT46_001693"
     CDS             14062..>15003
                     /locus_tag="VQT46_001693"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2371675.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQISHTSNSNHGVIEGNDALIYLMNQQQYLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNRQINRVHELERHIQSNNEEIERLIKW
                     EKLEIIPAHLEQFFFCKGKVGTIPRTVDNRLYNSFLENNIEVQEIFSNDREYGVVVFY
                     QSSCSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKNNLID
                     LQWQIDYILSIYARQISKNNLLSTPHLVALEGWIEETR"
BASE COUNT         5018 a         2285 c         2962 g         4738 t
ORIGIN      
        1 ccctattgac gacatctata atttggatat ttgtgtcttt gatatcgagt agttttgtga
       61 taaaatgtaa ttgttccata tgaatctttc taatgagttg tttggtcgct tttcattata
      121 gatcttatgg gacttttttt ctacaataaa ataggctcca taatatctat agtggattta
      181 cccactacaa atattataga gccgaaatta tcaggaaagt acaggagcct gaattttgga
      241 aagaagttaa cttgtctgat ttggaaaaaa ttcgtcttgc tattcgagat ttattacagt
      301 ttttggataa aacagaccgt aaaccctact atgttaactt tgaagatcgt atactctcca
      361 ctgttcacga gaccacagca tttttgcagg tcaacgatct tcggtcttac aatgaaaaag
      421 ttgagcatta tttgaaaact catctggatg aggagtccat ttctaagcta taccataata
      481 aaaagttgac atctgatgat atgcttgcac ttgaaaaatt gctttgggaa aaattaggta
      541 gtaaagcaga ctaccaaagt cattatgaaa ataaggcaat tccgagattg gttcgtgaga
      601 ttattggctt agatagagag tctgccaatc gtattttctc taaatttttg tcggatgaga
      661 atcttaatgc caggcagatt tcatttgtaa aattgattgt agactacatt gtagaaaatg
      721 gttttttaga gacgaaagtg ttaacgcaag agccgtttaa atcttatggt tctgttcaac
      781 tactcttcca acaccaacta ccagtacttc gtaatattgt tcaaatcatt gaacttatca
      841 ataatcgagc tggagaagcg gcttaaattc taaagtgatt gccatgctga gactcattta
      901 aaattaaaaa gagtagaaat ttatgctata tatgagaagt tttattagga agaatgtcat
      961 cgttttccta gaatacagta tcagttgtta agtggttgat aaatttcaaa gtagatactt
     1021 gtaccacgat gtttgttgat cgagttatta acaaaagagc tactttgatt ttaacccaaa
     1081 tcattcatac ctctctcaac tagatgtaac ttacaaaacc cctgacctca tgagccactt
     1141 tcttcctcct catgaggtca gttttacttt ctgctgttcc agtatcgttt ttcctcgcta
     1201 gatttcctca aaagggcaga ctcctccctt ggtgcgtcac acgatttttt catctcgact
     1261 gttctttaat gcatcattaa cgacgctttt cttccaggtg gttcataagg aacaggaaga
     1321 ttcaggttga cttttctaat cctagaataa agtgctgaaa acaattcgga ataggcatag
     1381 agactagaca atttgaggag ctgcttgcgt cctgttcgaa cacattttcc taccacgtga
     1441 agaaaaagat ggcggaagcg tttgattgtt aaagtttgga agtcacctcc agctagatgt
     1501 ttgagaaaaa gatagagatt gtaggcgata cagctcatca tcatacgaac ttcgtttttg
     1561 attaaggttg aactatccgt tttatcgcca aaaaatccct ccttcatctc cttgatgaaa
     1621 ttctcggctt gaccacgtcc acgataaagc tgaaactggt cttggcttgt tccactcgtc
     1681 atatttgtaa cgagagaaat aacatcgtag aacaagtttc cttcttttcg ttcagagaac
     1741 tggcagacac gacgcttgtg cgaccaagat cctgcttgat agagagtttc tgagtaggcg
     1801 gagtggggca agatggttaa gtcctcatcc tgtgggcaag ggagggaaag gtctccaaga
     1861 cggctcagaa cagtattttt cttgagtttt atgagttagt attgccctgt tttttcaatt
     1921 aaatcgtata atttgggggt cgcaaagcca ctatccattc gaaagagaag ttgattaaac
     1981 cgttctaaaa caggtgtgat aaagctgtct gcctcttcag aacaataacg attaccagga
     2041 cgaagctggg cattgaaaca ataacctgtc ttcccctcga aagcataaag aggatgatag
     2101 ccatgagcac gatagtgggc gttataagca acaccttctt gcttgccata agttgtgaaa
     2161 tgggtagaat cgatatctac aatgagttgg tttagctggt gaaactgtaa aaagaattcg
     2221 accaattcaa ggttgaggca tcgcaaacta tggactgttt cctcgtcagt tctggaaaga
     2281 aaacgggata aggttggctg tgaagcaagc tgccctcctt ccaacaattt tggaaagtag
     2341 gcatcagctg acaattcttt acaagcatag tccgttccat agcctgttaa cagttgaaag
     2401 aggaactgga caaggatatc tgaatccgaa taacgacagt agcggcgttg gtcattcgtt
     2461 actaaatact tagaaatccg ctcttttagt ttcaactggg aaaaaagttc ctgaaaaaag
     2521 ataagaccac catactgggt taaatgacct ccatcgaaag atagttggta aaaagacttg
     2581 ttttggaagt gatgatttgg taaactgttc atgtgagttt cctttctttt tgtgtttttt
     2641 tctacactta taccataaag gggaaattct tttttgtcta gtaaaaaaca cccattgggt
     2701 gaaaaaagaa accatacagg atctaagcta aggcaaggat tctggatggt ttttagatta
     2761 ggggtgaata attggggttt taaagaaata gaaaacaaaa agccgagcaa gaattcaatt
     2821 gcaggagaaa atgaaataat actcaatgaa aatcaaagag caaactagga aactagctgc
     2881 aggctgctca aaacactgtt ttgaggttgt agataagact gacgaagtca gctcaaaaca
     2941 tggttttgag gttgtagatg aaactgacga agtcagtaac catacctacg gcaaggcgac
     3001 gttgacgcgg attgaagaga ttttcgaaga gtataaatct tcctaggata aagcaaagag
     3061 cctgggacaa aatagttctc gaccacaaaa aagctagaga tttccaattg tggaacttta
     3121 gctttttaat tttgagtcgt tctcttattg tattttagga ggttattggc cataagtacc
     3181 aatcccatgt caattctcac ttgacgcttg cccctcagat tacatctctt gtaacccaaa
     3241 caagccttta tctgcccaaa gacaggtgac attctttagc tttcaagttt tgatagcctt
     3301 cgttcatata cagtcccttt tgaggggctg attcaggttc gtcggcgtag taaaccttga
     3361 tttcttgttt aaagtctgtc tgtgttttct gatgtttggt atggtgaaaa cgataatacc
     3421 agccatcagg atgtgtatag ctatcctcct tgtcattata gtaccaattc gctaagtttc
     3481 tagctgactg tttatagcct ctcttctgtt ccttatcaaa catggcatat ttaatcagat
     3541 ggtttacctc cttttcatct aactaaagga gaagcaatat ggctgaacga ttttgggaga
     3601 acttgtccat tattttggct gacagaaata tcagctggat tgagttaacc agaaaaatgt
     3661 ttgcgggaga gtttcactat ccaagtgaat tgaatcgttt gtatcaaaag attcgccact
     3721 agaagatgga acaacgaatg cctcaaagtc catgggtaga aaggattgtg caggtattag
     3781 atttagatta tgaagattta tttcggaggt aattatgaaa agaataattc cagtttatat
     3841 attccaacaa gtaaatgtcc tattggtatc tctatactta ttgaaatttc tttgtagcga
     3901 tgagttaact atactacaga ttctctatgg agcgtcactc atttcttttt tatggatgta
     3961 tggtcaacga aaacaagtga tcaaggttaa tatgaaaact aggatacaat ggcttggtat
     4021 tggattcgtt agcctactga ttataagtct atgttttagt ctaatccatg cgcaagaaag
     4081 cacgaatcaa gcaaacttaa ttggacttca acatcaaatt ccttggtttt catttttatt
     4141 gtttttaatc aatgcgagta tggttgaaga atttctgtat agagaaattt tatggaactt
     4201 ggttagaaaa ttagatattc gagttgcttt gacaagtgtt ttatttgcct tagcacatca
     4261 tccaggaacc attatagctt ggtgtttgta tgtatcgctg gggatgtttt tagggcttgt
     4321 acgctacaaa ttggacttat ggggcagtat ggggctacat ttggtgtgga acctactagt
     4381 ttatagtttg ctgctttttt aaaataagtg atctgattta tctcataaat cagtagtttt
     4441 tataggatta tttttaattc ggaaacaaaa atgtattaac agcataaaat aaagaaacta
     4501 ggaacatttt ttttattttt tagaaataaa atgttgtata gaaattccga aagaaataat
     4561 aaaatcaaaa taaaaattaa taaaataggt atatttgaac atattgacgt cgacaaatgt
     4621 tcttgcaaga cataaaatac aaataaaaag aataaaaaat ttttatattt ttatatttgt
     4681 tgttctgtta taaaatgaaa gaaattagaa actagtttct aaatcatgaa aaatattgaa
     4741 aaaaaaaaaa taagtgttaa aataaagaat gtaaacgttt acttcaataa aggagctcat
     4801 atgttactgc aaaaagaact aattccaatg atagaagcta acttaccaaa tatggcatat
     4861 gctgaaaaag acattgctaa attcttctta aaacagcaac ctctgaataa ttattcatgt
     4921 aaggcattgt gcgaatgcct taatgtatcc aaagcaacat tgactcgatt tgcgaaaaaa
     4981 tgtggtttta aaggttttag acaattcatt ttcaaatacc aagagatgat tcgtgagaaa
     5041 gaaaagttag cattgtatac agaggctaca gaaaaagttt tatccgacta tgaagaaatg
     5101 ttgagaaaaa cttacacggt tcttgatgaa gttcaacttg agcgtattgc tgagatgata
     5161 gaaactgctg agcgtgtata tctttatggt aaagtaagtt ctgttcttgc tttacaagaa
     5221 atgaagatga gatttatgcg tctcggagtc attggtgaag tattatcaga cgaggatatg
     5281 attttgtgga atagcttatt acttaatgaa aattgccttg tcattggagc atccgtttca
     5341 ggtcaaactg atattgtact agaaggtctt caaaaagctg cggataaagg cgctaaaaca
     5401 gttttaatga ctacaagaaa atttgacgaa gaagattgtt tctttgatga actattgtta
     5461 ttagcttcga ccaatcatct ctcgtatggc aatcgcatat cacctcagtt tccaatactt
     5521 ttaattacag actgcttatt ctctcattat ctggaaagtc cagagagaca atattattac
     5581 aatcaaacta ttatccataa ggaggaataa taaaatgagt caaatttgga ctaaagaaaa
     5641 atttataagt caagtccatg gtggagtcat tgtttcttgt caagctttac ccggtgaacc
     5701 cctttataat gaagaattta gcttgatgcc ttttatggct aaagcagctt tagaggcagg
     5761 agcagtgggc attcgcgcaa attctgtgcg tgatattaaa gcaattcaga aagtagtaga
     5821 tttaccaata attggaatta tcaaaagaga ttatccacct caagaaccat atattactgc
     5881 tacgatgaaa gaagtagatg aacttgtaga atgcggaaca acagtcattg catttgatgc
     5941 aactttaaga ccaagatatg atggcttagt tatcaatgaa tttatcaaaa aaataaaaga
     6001 aaaatatcct aatcaattgt tgatggcgga tgtaagtaat tttgatgaag gtctctatgc
     6061 atttaaatca ggcgttgatt ttgttggtac aacattatca gggtacacaa gtacaagtgt
     6121 acaatcagat gagcctgatt ttgaactaat gaaaaaattg gctgatttta atattccggt
     6181 aattgccgaa ggaaaaattc attatccaga acaattaaaa aaagcttata gtttaggtgt
     6241 taccagtgtt gtcattggtg gagcgattac acgtccaaaa gaaattgctc agcgatttat
     6301 taatgtcatc aaataaaaaa caatataaag gagaaatctg atgaaagatt taactaaata
     6361 caaaggcgtt attcctgcat tttatgcttg ctatgatgaa aatggtgaaa ttagccaaga
     6421 acgtgtaaaa tctctggtgc aatatttcat tgacaaaggt gtaaaaggta tctatgtaaa
     6481 tggttcttca ggtgaatgta tttaccaaag tgtagaagat cgtaaacaaa ttattgaagc
     6541 tgttatggaa gttgctaaag gtaaattaac agttatcaac catgttgcat gtaataacac
     6601 gaaagatagt attgaattgg caaaacattc agaaagtgtt ggagtcgatg ctattgctgc
     6661 tatcccacct atttacttca aattgccaga atattcaatt gcagcatatt ggaatgcaat
     6721 gagtgaagct gcgccaaata cagattttat catttataat attccacaat tggcaggggt
     6781 tgcgttgact ggtagtttgt atgcaacaat gcgtcaaaat cctcgtgtga ttggagttaa
     6841 aaattcttct atgcctgtac aagatattca aatgtttgta gctgcaggtg gagaagatta
     6901 cattgtattc aatggtccag atgaacaata tcttggtggt cgcttgatgg gagcagaagc
     6961 tggtattggt ggtacttatg gcgttatgcc agatttgttc ttgaaattgg aaagtttgat
     7021 tcaagaacga gatttagata ctgctaaaaa acttcaatat gctatcaatg aagttatcta
     7081 taagatgata tcaggtaagg caaatatgta tgctgtagca aaagaggttt tgcgtctaaa
     7141 tgaaaaactt gatttaggtt ctgttcgtca acccttagaa gcattggcag aaggtgactt
     7201 ggaagttgca aaacaagcag cagaacttat tcaacaagca cgaaaagaat ttttataata
     7261 aataaaatca atatggagat atgttatggg cacaacagga tttacaataa ttgacttaat
     7321 tatcttgatt gtttatttac ttgcggtgtt ggttgcaggt atctatttct ctaaaaaaga
     7381 gatgaaagga aaagagttct tcaaaggaga tggttcggtt ccttggtatg ttacttcggt
     7441 atccattttt gccacaatgc tcagtccgat ttccttcttg ggactcgctg gtaactctta
     7501 tgcaggtagc tggattttat ggtttgctca attagggatg gtagtagcta ttccactgac
     7561 aattcgtttt atcttaccta tctttgcacg gatagacatc gatacggcat atgattactt
     7621 ggataaacgt tttaattcta aagcacttcg tattatttca gcactcttgt ttattattta
     7681 tcaattggga cgtatgtcta tcattatgta cctcccatca gctggtttat cagtattgac
     7741 aggaattgac atcaatattt tgattatttt gatgggtgca gttgcaattg tttattctta
     7801 cactggtggt ctaaaatccg tattatggac agactttatt caaggtgtga ttctgattag
     7861 tggtgtcgtt ttagctttat ttgtactgat ggctaatatt aaaggtggct ttggtgcagt
     7921 agcagaaaca ttagcaaacg ggaaattcct tgctgcaaat gaaaaacttt tcgatcctaa
     7981 cttgctttca aactccatct ttttaattgt gatgggttca ggctttacaa tcttgtcttc
     8041 ctatgcttca tctcaagatt tggttcaacg ttttactaca acacaaaata ttaagaaact
     8101 taataagatg ttgttcacaa acggtgtctt gtcacttgca actgcaacag tcttttactt
     8161 gattggtaca ggcttgtacg tattctatca agtacaaaat gcaggtagtg cagctagcaa
     8221 tatccctcaa gaccaaatct ttatgtactt tattgcatac cagttaccag taggtatcac
     8281 aggtttgatt ttggcagcga tttatgcagc atctcaatca actatttcaa caggtttgaa
     8341 ctctgttgca acttcatgga cattggatat tcaagatgtc atttctaaaa atatgtcaga
     8401 cgatcgtcgt acgaaaattg cacaattcgt atctctagca gtaggtttat tctcaattgg
     8461 tgtttccatt gtcatggctc actcagatat taaatctgca tacgaatggt tcaatagctt
     8521 catgggactt gtacttggtc tacttggtgg tgtatttatt cttggatttg tttctaaaaa
     8581 agcaaataaa caaggtgctt atgcagcgct gattgtatca actatcgtca tggtatttat
     8641 taaatacttc cttcctccaa cagctgtgag ctactgggca tattcattga tttcaatctc
     8701 tgtatcagta gtttcaggtt atattgtatc tgttcttact ggaaataaag tatctgcacc
     8761 taaatataca acgattcatg atattccaga aattaaagcg gattcaagtt gggaagttcg
     8821 tcactaatag aaaagagaaa ataatatgat tatttctgaa caatctgatt ttagacgata
     8881 tgcttctatc aataaacatt tttcaaaagt ctgtgatttt ttagaaaata caaatttgac
     8941 agatttagtt gatggaaaag ttgatattga cggggaaaat gtttttgcaa attgtatgat
     9001 ctatctagct gatggagtcc caggagatat ttttgaaact cataagaaat atttagatat
     9061 tcatattgtt gttgaaaata ctgaaaaaat ggcagtaact tccccagttc gtgcccagtc
     9121 acgtgtacct tttagcgaag aaaaggatat tgctttttac gatagcaaag actatcaaat
     9181 tgttgaattg cttccaggga atatgttggt gacttttgaa gaagatcttc accaaccaaa
     9241 gattcattgc aatgatgagc ctgttaaaaa acttgttatt aaagttttaa acgaggaaaa
     9301 ataaaatgaa aaaaaatatt aaacaatacg taaccttagg tactgcagtg gtattatcag
     9361 catttgttgc taactcagtt gcagctcagg agactgaaac ttctgaagta tcaacaccag
     9421 agttggtgca acctgttgca ccaacgactc cgatttcgga agtacaacct aaatcgggta
     9481 actcttcgga agttactgta caacctagaa cagtcgaaac tactgttaag gatccatctt
     9541 ctgcaacgga agaaactcct gtcttagaaa aaaataatgt tactttaaca gggggcggag
     9601 aaaatgttac taatgagtta aaggataaat ttactagcgg tgactttact gtagtgatta
     9661 agtacaatca gtctagtgag aaaggcttac aagctctgtt tggaatatct aattctaaac
     9721 ccggtcaaca aaatagttat gtagatgtgt tccttagaga caatggtgaa ttgggaatgg
     9781 aagcgcgtga tacttcttcc aataaaaatc acctagtatc cagacctgct tcagtttggg
     9841 gtaagtacaa acaagaagct gtgactaaca ctgttgcagt agtagcagat tcagtcaaaa
     9901 aaacatattc tttatatgca aatggtacaa aagtagtaga aaagaaagtg gataacttct
     9961 taaacatcaa ggatattaaa ggtattgatt actatatgct tgggggagtg aaacgtgcag
    10021 gaaaaacggc gtttggtttt aacggaacac tagaaaatat caaattcttt aatagtgcat
    10081 tggatgaaga aactgttaaa aagatgacaa caaacgctgt tactggacat ttaatttata
    10141 cggctaatga tacaacaggt tctaactatt tccgtattcc agttctgtat acttttagca
    10201 atggtcgggt attttcaagc attgacgctc gttacggcgg aactcatgat tttttgaata
    10261 aaattaatat tgctacaagt tatagtgatg ataatggtaa gacatggact aaaccaaaat
    10321 taacattggc attcgatgat tttgcgccag taccattaga atggcctcgt gatgttggtg
    10381 gacgtgactt acaaatcagc ggtggtgcaa cctatattga ctctgttatt gttgaaaaaa
    10441 ataacaaaca agtactcatg tttgcggatg tgatgcctgc tggagtaagt tttagagaag
    10501 ctactagaaa agattcaggt tataaacaaa ttgatggtaa ttattacctt aaattaaaga
    10561 aacaaggtga tactgattac aattatacta ttcgtgagaa tggtactgta tacgacgatc
    10621 gtaccaacag accaactgaa ttttcagtag ataaaaattt cggtattaaa caaaatggta
    10681 attatttgac agtagagcaa tattcggttt catttaaaaa taataaaaag actgaatatc
    10741 gtaatgggac tcacgtccat atgaatatct tctacaaaga tgcattgttc aaagtagtgc
    10801 caacgaacta tattgcatat atttctagca atgatcatgg cgaatcttgg tctgcaccaa
    10861 ctttattacc tcctataatg ggacttaatc ggaatgcgcc ttatttgggt cctggacgtg
    10921 gaatcattga aagctcaact ggacgtattc ttattccgtc ttacactggt aaagagtctg
    10981 cattcattta tagtgacgat aatggagcat cttggaaagt taaagttgtg ccacttcctt
    11041 ctagttggtc agcagaagca caatttgtag aattgagtcc aggagtaatt caagcataca
    11101 tgcgtacaaa taatggtaaa attgcatatt taacaagtac agacgcaggt actacttgga
    11161 gtgcaccgga atatttgaaa tttgtttcaa atccaagtta tggaacacaa ttatcaatca
    11221 tcaattatag tcaactgatt gatggtaaaa aggctgtcat tttaagtact ccaaactcca
    11281 caaatggtcg taaacacgga caaatttgga ttggtctaat taatgatgat aatacaattg
    11341 attggcgtta tcatcacgac gttgattata gtaactatgg atactcatat tcaacattga
    11401 cagagttacc aaatcatgaa attggattga tgtttgaaaa atttgattca tggtctcgta
    11461 atgaacttca tatgaaaaat gttgtaccat atataacatt taagattgaa gatctgaaaa
    11521 agaattaaag ctgaaatttg aaaatatata aaaagaggat aaaaattatg gtaaattacg
    11581 gtattgttgg agctggatat tttggagctg atttagctcg ctcaatgaac aaaattgaag
    11641 atgcaaaagt ggttgcggta tttgacccaa atcatggaga agaagttgct caagagttgg
    11701 gatcagatgt ttgtgcaagt ttagatgaac ttgtagcacg tgaagatatt gattgtgtga
    11761 tcgtagcttc acctagctac cttcaccgtg aaccagttgt gaaagctgct caacatggca
    11821 aacacgtatt ttgtgaaaag ccaattgcat tgtcttatga agattgtaaa gccatggttg
    11881 acgcatgtaa agaaaataat gttatcttta tggctggtca catcatgaac ttctttaacg
    11941 gtgtacacca tgctaaagaa ttgattactc aaggtaaaat cggtaaagtt ctttattgcc
    12001 atgccgctcg tacaggttgg gaagaacaac aaccaactgt atcatggaag aaacttcgtt
    12061 ctcaatctgg aggacatttg taccatcata ttcatgaatt agattgcatt cagtttatca
    12121 tgggaggact tcctgaaaaa gcgacaatgg taggaggcaa tgtatatcat aaaggtgaaa
    12181 actttggtga tgaagatgat atgctcattg taaacttaga atactctgat gatcgttatg
    12241 ctgttttgga atatggtaat gctttccgtt ggggtgaaca ctacgtcttg attcaaggaa
    12301 ctgaaggagc tatcaaactt gatttgttca atactggagg tactcttcgt gttaaaggtg
    12361 aaggagaatc acacttctta gttcatgaaa ctcaagagga agatgatgac cgtacagcta
    12421 tctataccgg tcgtggtatg gatggagcaa ttgcgtacgg taaaccagga gtacgttgcc
    12481 cattatggtt gcaaacatgt attgataaag aaatggaata tctacatgac atcattaaag
    12541 gtggagaaat tacagaagaa tatgaaaaac ttctcaatgg tgtagctgct ttagaatcaa
    12601 tcgctaccgc tgatgcatgt actttatcag ttaaagaaga tcgaaaagta agtctttcag
    12661 aaatcacaaa tgcttaactt ttgtaaaaca gaatagtaaa ttcttatcat tatataattt
    12721 ctaaagttct gtgatacaac tcattgaata aagaaataga gatgggactg ggataatgcc
    12781 cagtcccatt ttttatcaaa aagtaatgag atcaaaaatg tgggagtgat gaaatgaaga
    12841 ttatagggat cgatattggc ggaacaacaa ttaaagcaga tttatacaat gagtttggaa
    12901 cgagtttaaa tcagttcaaa gagatagaaa caattattga ctatgatttg ggaacgaacc
    12961 agatattaaa tcaggtctgt gatttaattg gtgagtatat tttaaatcat tcaattgatg
    13021 gtgttgggat ttccactgct ggagttgtta atgctaatac aggagagatc atctatacag
    13081 gctatacaat accagggtat atcggagtaa actttacttt cgaaatagaa aaacgttttg
    13141 ggttgtctac ttttgttgaa aatgatgtta attgtgctgc attaggtgaa ttgtggaagg
    13201 gacaagccaa agataagaaa aatgtagtaa tggttactat tggaacaggt ataggaggca
    13261 gtattattgt caatggacaa attgttaacg gatttaacta tactgctggt gaagtaggct
    13321 atattcctgt aggtaattcg gattggcaaa gcaaagcctc aacaaccgca ttgattcatt
    13381 tatatcaaaa gaaaagcttg aaaactaatc aaactgggcg tactttcttt actgatttaa
    13441 gagctggaga taaagtcgct aaagaaactt ttgaaatttt tgtagaaaat ctaacaaaag
    13501 gtttattaac gattacttat ctacttaatc cagaaattct catattagga ggtgggatcc
    13561 tggctaaaaa ggatattttg ttacctgaaa ttcaaagttc tttagctaaa aatgcaatgg
    13621 ataataggtt tttgcctaaa aatcttgtgg cagctacatt aggaaatgaa gctggtcgta
    13681 taggagctgt aaaaaatttc ttagatagaa tttctaataa atagtatgaa agataaggag
    13741 gtgtcacaat gactaactct gtattttcga caatgcaaga tattgagaat gttgcaaccg
    13801 atattataaa atcatatgat aatgagattt atacttataa agctgtttcc caagaagaat
    13861 tggaaaaact agaaaaaagt tatgatgaaa aaagtcacga agaattagtt tcaatagaaa
    13921 gcaatttaga aatgaaacaa cagaacctta ttgatgaggt taataaaaca atcaaggaaa
    13981 attatgaaaa gattcagtat atttcatcaa gtaggagagg agaatttgta gaaaaaatta
    14041 ttggtagggt ggtagaaaaa tatggctatt agtcagatga aaagaatttc tctactattt
    14101 tctaaaagta gtcttgatga tgttttaaaa actattcaag aactagagtc agtgcagttc
    14161 cgtgatttaa aggttcagga taactggtca gaagctctag aaaaagatga ggttgtattt
    14221 ccaactattc aaatttctca tacttctaat tccaatcatg gggttattga aggaaatgat
    14281 gccttgattt atttgatgaa tcaacaacaa tatttagaag caactgtaga gaaattacaa
    14341 gaatacctac cgaaagaaaa cacgtttaaa ttattacagc aacctccgat aacgacctct
    14401 tatgaagaat tagaaaaatt tggtaaagct aatgttgctg agggtgttct taaaaaagtg
    14461 aatcgtcaaa taaacagagt tcatgaatta gaaagacaca ttcaaagtaa taatgaggaa
    14521 atagagagat taataaaatg ggaaaaatta gaaattattc ctgcgcattt agaacaattt
    14581 tttttctgta aaggaaaagt cggaacaatt ccaaggactg tagataatcg cttatacaat
    14641 agttttttag aaaacaatat tgaagttcaa gaaatatttt ctaatgatag agagtacggt
    14701 gttgttgttt tctatcagtc cagttgctct attgattttg atgaatactt atttgaacca
    14761 tttgattatt ctagaaagga attaccgaag cagcgagtag tagatttgga tcaagaaaac
    14821 atgcagttaa taactgaaaa agagaatatt atcgcatcgt tgcaagattc aaagaataat
    14881 ttgatagatt tacaatggca aattgactat attttatcta tctatgctcg tcaaatctct
    14941 aagaataacc ttttgagcac tccgcatcta gttgcactag aaggatggat agaagaaact
    15001 cgt
//
LOCUS       DAVAZV010000054        14254 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVAZV010000054 DAVAZV010000000
VERSION     DAVAZV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14254
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.054"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            3..350
                     /locus_tag="VQT46_001694"
     CDS             3..350
                     /locus_tag="VQT46_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371676.1"
                     /translation="MLRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWMKEQAEA
                     YQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPP
                     AFYQQYFLKNMVE"
     gene            369..2171
                     /gene="pepF"
                     /locus_tag="VQT46_001695"
     CDS             369..2171
                     /gene="pepF"
                     /locus_tag="VQT46_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2371677.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEVLKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTFYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGIYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            2173..2886
                     /locus_tag="VQT46_001696"
     CDS             2173..2886
                     /locus_tag="VQT46_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET2371678.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELENFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            2953..3894
                     /gene="prsA"
                     /locus_tag="VQT46_001697"
     CDS             2953..3894
                     /gene="prsA"
                     /locus_tag="VQT46_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET2371679.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(4011..4352)
                     /locus_tag="VQT46_001698"
                     /pseudo
     CDS             complement(4011..4352)
                     /locus_tag="VQT46_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            4765..4860
                     /locus_tag="VQT46_001699"
                     /pseudo
     CDS             4765..4860
                     /locus_tag="VQT46_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5113..5733)
                     /locus_tag="VQT46_001700"
     CDS             complement(5113..5733)
                     /locus_tag="VQT46_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2371680.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLYTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(5733..6215)
                     /locus_tag="VQT46_001701"
     CDS             complement(5733..6215)
                     /locus_tag="VQT46_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET2371681.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(6215..7057)
                     /locus_tag="VQT46_001702"
     CDS             complement(6215..7057)
                     /locus_tag="VQT46_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET2371682.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(7152..7952)
                     /locus_tag="VQT46_001703"
     CDS             complement(7152..7952)
                     /locus_tag="VQT46_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET2371683.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            8096..9475
                     /gene="glmU"
                     /locus_tag="VQT46_001704"
     CDS             8096..9475
                     /gene="glmU"
                     /locus_tag="VQT46_001704"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET2371684.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            9485..10030
                     /locus_tag="VQT46_001705"
     CDS             9485..10030
                     /locus_tag="VQT46_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2371685.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTARRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            10042..10356
                     /locus_tag="VQT46_001706"
     CDS             10042..10356
                     /locus_tag="VQT46_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET2371686.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            10373..11065
                     /locus_tag="VQT46_001707"
     CDS             10373..11065
                     /locus_tag="VQT46_001707"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET2371687.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            11142..11633
                     /gene="rocS"
                     /locus_tag="VQT46_001708"
     CDS             11142..11633
                     /gene="rocS"
                     /locus_tag="VQT46_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET2371688.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            11731..12321
                     /locus_tag="VQT46_001709"
     CDS             11731..12321
                     /locus_tag="VQT46_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET2371689.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            12330..14093
                     /locus_tag="VQT46_001710"
     CDS             12330..14093
                     /locus_tag="VQT46_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET2371690.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTCAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
BASE COUNT         4485 a         2552 c         2969 g         4248 t
ORIGIN      
        1 aaatattgcg tcttccctat aagaaacaaa aaatatctca ttttacagtt tctgaggaca
       61 aggacatctg tcgctatatc cggcaacaac tttattatca aaatctcttt tggatgaaag
      121 aacaagcaga agcctatcaa aagggagaaa atatcctgac ttatggactg aaagaatggt
      181 atccacaaat tcgaccaata gtgggcaaat ttttccagat tgaacaagac ttgactagct
      241 attatcagca cttttatacc tattaccaaa aaaatcctca aaatgattgg caaaagcttt
      301 atccaccagc cttttatcag caatatttct tgaaaaatat ggtagaatag aaaggatgga
      361 ggaatctaat ggtattacaa agaaatgaaa taaatgaaaa agatacatgg gatctatcaa
      421 cgatctaccc aactgaccag gcttgggaag aagtcttaaa agatttaaca gaacaattgg
      481 agacagtagc ccagtatgaa ggccatctct tggatagtgc ggataaccta ctagaaatca
      541 ctgaattttc tcttgaaatg gaacgccaga tggagaagct ttacgtttat gctcatatga
      601 agaatgacca ggatacacgt gaagctaagt atcaagagta ctatgccaag gccatgacat
      661 tctacagcca gttagaccaa gccttttcat tctatgagcc tgaatttatg gagattagcg
      721 aaaagcagta tgctgacttt ttagaagctc aaccaaagct gcaggtttat caacactatt
      781 ttgacaagct cttgcaaggc aaggatcacg ttctctcaca acgtgaagaa gaattattgg
      841 ctggagctgg agaaatcttt ggttcagcaa gtgaaacctt cgctatcttg gacaatgcgg
      901 atattgtgtt cccttatgtc ctagacgatg atggtaaaga agttcagcta tctcatggga
      961 tttacacacg tttgatggag tctaaaaaac gtgaggttcg ccgtggtgcc tatcaagctc
     1021 tttatgcgac ttacgaacaa ttccaacaca cctatgccaa aaccttgcaa accaatgtta
     1081 aggtgcaaaa ttaccgtgct aaagttcgta actacaagag tgctcgtcat gcagccctcg
     1141 cagcgaattt tgttccagaa agtgtttatg acaatttggt agcagcagtt cgcaagcatt
     1201 tgccactctt acatcgctat cttgagcttc gttcaaaaat cttggggatt tcagatctca
     1261 agatgtacga tgtctacaca ccgctttcat ctgttgaata cagttttacc taccaagaag
     1321 ccttgaaaaa agcagaagat gctttggcag tcttgggtga ggattacttg agccgtgtta
     1381 aacgtgcctt cagcgagcgt tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg
     1441 cctactctgg tggttcttac gataccaatg cctttatgct tctcaactgg caggacaatc
     1501 tggacaatct ctttactctt gttcatgaaa caggtcacag tatgcattca agctatactc
     1561 gtgaaactca gccttatgtt tacggagatt actctatctt tttggctgag attgcctcaa
     1621 ctaccaatga aaatatcttg acggagaaat tattggaaga agtggaagac gacgcaacac
     1681 gctttgctat tctcaataac ttcctagatg gtttccgtgg aacagttttc cgccaaactc
     1741 aatttgctga gtttgaacac gccattcacc aagcagatca aaatggggag gtcttgacaa
     1801 gcgatttcct aaataaactc tacgcagact tgaaccaaga gtattatggt ttgagtaagg
     1861 aagacaatcc tgaaatccaa tacgagtggg ctcgcattcc acacttctac tataactact
     1921 atgtatatca atattcaact ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc
     1981 atggtagtca agaagaccgt gaccgctata tcgactacct caaggcaggt aagtcggact
     2041 atccacttaa tgtcatgaga aaagctggtg ttgatatgga gaaggaagac tacctcaacg
     2101 atgcctttgc agtctttgaa cgccgtttaa atgagtttga agcccttgtt gaaaaattag
     2161 gattggcata aaatggttga atcgtatagt aagaatgcta accataacat gcgtcgtcct
     2221 gtcgtcaaag aagaaattgt agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc
     2281 ttgaaagaat tggaaaactt tgcccgcaag gaaaatattc ctattattcc ccatgaaacg
     2341 gttgcttatt tccgttttct tatggaaacc atgcagccta aaaatattct ggaaattggg
     2401 acggctatcg gtttttcagc tctcttgatg gctgaacatg cgccaaatgc taagattaca
     2461 actattgatc gtaatccaga aatgattggt tttgccaagg aaaattttgc ccagtttgac
     2521 agtcgcaagc aaatcactct cctagaggga gatgcggtgg atgtcttatc tacactgaca
     2581 gagtcttatg atttcgtctt tatggattct gccaagtcta aatacatcgt ctttctgcca
     2641 gaaatcctca aacatttgga agttggtggt gtggttgtct tggatgatat ttttcaaggt
     2701 ggtgatgttg ccaaggatat tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc
     2761 cttcaaaaat tatttgatgc aaccttagac aatccagaac tcaccgcaac attagtgcct
     2821 ttaggagatg gtattctcat gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc
     2881 gaatgatttt cagaaaaatt taagaaaaaa tagtaaaata gatagagtaa cacttatctc
     2941 aaaggagtag acatgaagaa aaaattattg gcaggtgcca tcacactatt atcagtagca
     3001 actttagcag cttgttcgaa agggtcagaa ggggcagacc ttatcagcat gaaaggggat
     3061 gtcatcacag aacatcaatt ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc
     3121 ttgttaaata tgaccatcca aaaagttttt gaaaaacaat atggctcaga gcttgatgat
     3181 aaagaggttg atgatactat tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt
     3241 gtcttgtcac aagcaggtat gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa
     3301 ttagttgagt tggcagttaa gaaggtagca gaagctgaat tgacagatga agcctataag
     3361 aaagcctttg atgagtacac tccagatgta acggctcaaa tcatccgtct taataatgaa
     3421 gataaggcca aagaagttct cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta
     3481 gccaaagata attcaactga tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat
     3541 tctgcttcaa cagaagtacc tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat
     3601 ggtgtttctg atgtgattac agcaactggc acacaagcct acagtagcca atattacatt
     3661 gtaaaactca ctaagaaaac agaaaaatca tctaatattg atgactacaa agaaaaatta
     3721 aaaactgtta tcttgactca aaaacaaaat gattcaacat ttgttcaaag cattatcgga
     3781 aaagaattgc aagcagccaa tatcaaggtt aaggaccaag ccttccaaaa tatctttacc
     3841 caatatatcg gtggtggaga ttcaagctca agcagtagta catcaaacga atagtccaaa
     3901 tcaatgagtc agggaaaaaa actcgacttc aggaaaaaat gaagcaaaca ttcccacaat
     3961 aaaacgcata gtacaaggtt tgtactgacc ccaaaagtta gacaattaat ttatctgaag
     4021 gatttagttc tgtattgcac agggctaagt ccttttagtt ttaccttaat tctcttattg
     4081 ttgtaataat caatatagtc tataatggct tgttccaatt gattaagtga tttaaatgtt
     4141 ttctcatagc cataaaacat ttcggatttt aaaatgccaa agaaagattc catcctaccg
     4201 ttgtcttggc tgtttccttt gcgtgacata gatgcttgaa ttcccttact ctctaggaag
     4261 cgatgataag aatcgtgttg gtattgccag ccttggtcac tatggagaat cgtattctcg
     4321 tagtgcttct ctttgaatgc ctgttccaac attaacgatc aatcaattta atcatgtacc
     4381 taatattaga attgtttatc ccaaatttat ttgaaagctt ctctaagcta tatccttgtt
     4441 ttctaagttc atagatctga actttatcat cataagttaa tttcataata aaaacacccc
     4501 aaaagttaga ttttttctgt ctaacttttg gggtgtagtt catgtacacc tgatatgatg
     4561 cgttttataa ttttaaagac tttttgacca gcctcatttt tttaacttga tactcagtga
     4621 aaagcaaaga ttaaactagg aagctagctg taggctgctc aaagaacagc tttgaggttg
     4681 cagataaaac ttgtgaggtc accaacatat ataatgtgaa gctgacgtga cttgaataga
     4741 ttttagaagg gtatgagtct ggaagtttta atggataatg caagattcca tagaatgggt
     4801 aagctagagt tcttatgtga agagtttggg cataaacttt taccttttcc tccctactca
     4861 tcttagtata gaaaagtgaa tctaaaatag tacataactg cttctaaaac attcttataa
     4921 attgatttaa attctcaaat catattattc agttcttatt tcattttgct ctacaatcct
     4981 gttgagaaga cacgtgttca tatcaaaaag gtattggcaa gttgcaatac ctttttacaa
     5041 ggttcttttg tcttattttt gtttcaactg actatatctc ctatggttct agttcagaag
     5101 gctaggctat aattatgatt gataagaagt atcattccaa gtattgagag tgaatgtttc
     5161 aaaatcatgg gtttctataa tggtcaggct ggcatttgct agaccgccat ctttacgaag
     5221 aagtggttct ttatagccta ggagagtacg aagactggca gtaagattgg cgccgtgtcc
     5281 gacaattaga atacgctcag ctggactatc ttttaatgat ttgataaatt ggatggtccg
     5341 ttgagttgta ctatagaggg attcggctcc gaacattcga gtgtcaaatt gagcaagatt
     5401 tgaacgaaaa gcctggattt gttgcgggta aatagcttcc aaggttgcaa ttttcaaacc
     5461 ttctaacttc ccaagttgcc attcacggag attaggaacg atttctaaag aacagggggt
     5521 atagagttga ctttggataa tctcagcaga tttgaccgct cgaggtaaat cacttgaata
     5581 aatctgatca aaaggaattt ccttgagata ctggccaagt cgttttaggg tttcaatgga
     5641 ttcaggaaga agaggagaat caccgctagc accttgaaaa cgaccttctt ggttccagag
     5701 ggtacgaccg tggcggacaa agtagagttt cattacttga tgtcctccaa aatatctaca
     5761 aagtctgcct ttacaaagct agccaagtct tgtggcgcga cgataatgct gtgtccgact
     5821 tcgcctgcag agacaatcat tcgatccaaa tctagagcaa ttttatcgat aaaaatggga
     5881 taattgtgtt tctgacgaat tccgacagga ttattggctc catgaatgta accagttgtt
     5941 ttttctaagt ccttttgtgg aatcatgctc acttttttat tgccagaaat tttagctagt
     6001 ttcttttcag acaagtgctg agtgataggg acaattccga taatcggtcc ggtcttgtct
     6061 cccaaaagcg ccaaggtttt gaaaatctga tctcgttcat aaccttgagg aagctctcct
     6121 tctagggcat tgatttgaat cccctgatga gggatagctg ctttagatag gatttgttcc
     6181 accaatgttt ttttgatttt aacttttttt gccattattt atatttatcc tccaattgac
     6241 tcatccaaat accaagccag attcccagcg caaagaagaa ggcgatgatg acataaccga
     6301 caagtgaaag tcctgtgtat tggatacttt cagcgtttcc tgcatttgga attaagatca
     6361 aaagggtact tgataggacg ataccgatga tgaaatgata gacgcgtgag tggtagttgt
     6421 ttaaggcata atccatcaat tttgaaaaaa cgatgagagt tgcacctgca ccaattccaa
     6481 tcggaaagaa ggttcccaag agatcaaaag ttttaaaacc agtcaacata ggagcataga
     6541 gtcccaaaat caaaagtaag ttcgatgggc tgaggccagg aaccaagacg ccaagggcca
     6601 atagtgcgcc tgctaggacg aagttaagaa agctggcgct taaggttcca acgacaaaat
     6661 ttaaggcata gagtcctaat ccagaaatga taaaggttgt ccataaccaa gctaaatcaa
     6721 tcttgtctcg gtcagattct cgagttgatt ctttgaggag gctaggaact gtaccgataa
     6781 tagctcccgc aaagctccat aatacaaaga cctgataatt ttcaagcagg tattcaatcg
     6841 ggtaggaaaa taagccgatt cccagaagca taccgatggc aactggaata aagtacaaaa
     6901 cattttcttt aaggtcttta aagggatggg ccagaaagcc aatcattcgt tcatagattc
     6961 ctaagattgc tgctagaacc cctccggaaa ttcccggtag gataaatcca agagcaatta
     7021 caatcccttt aataacgcgt gctaaccatg agagcatata tttcctccaa ctatttctat
     7081 ttcaaaaatt ccttactata ttgtatcaca atcagacaca aaaagaaaaa gcaaatgata
     7141 aacaaatgct tttaaggttt taaaaaaagt tttcgaaagg tttcttcttt attttttaag
     7201 ggagagataa cgttgatatc taaatcgtgg tcaaagccgg caatttttcc tttagatgtg
     7261 tattggtgaa tatcataatc taaatcagtt ttaggactgc tctccaaaaa tcctgagtct
     7321 gagccgtagg acggaatcca aacagaggta aacttgcctg tatcaatact gtgttcttcc
     7381 atgaagtaga caccaacgta gatgccgatg tttttagcac ctagtgatgc tagttttgct
     7441 cgaaagtttt cgacaccttc gttcatatta gacatggttt tgtcttccac gtcaagccaa
     7501 tagtaactag ggctgtaagg agaggcagca ttgtagaaaa cttcggcagc cttttccatt
     7561 tcttggacac tttttccagc tacataagcg tagacagcaa ctgggacatt ccgcttttga
     7621 agttcagtga tatgactctt ataggccttg tctattccat tgataaatga agcatcattt
     7681 tcttttgttg tttgagcacc actgtgaaca cgaacaatag cacctgaaat attttgtgag
     7741 agggcatcgt agttgatttc ctcaggacgc tgccagccag agaggtcaat aatcggtttg
     7801 tctaagtgtt tcaaagcctg tgcttcaatc tgtgctatat tggattttgt tttaaacgat
     7861 tggctgtcat taagtgggcg attgatgatt aaaatgaaca tcataatccc aaaaaaacta
     7921 aataaaataa gtggatgaat ttgttttctc atatcttata agtctaccct aaaaatcaaa
     7981 aaaaatcaaa aaaatgggtt aaggaagaga ctttagagca ttttttcatt caagagtgcg
     8041 gaatgatttg aaatatggta taataaaagg gaatttctac agaaaagaga agattatgtc
     8101 aaattttgcc attattttag cagcgggtaa agggactcgc atgaaatctg atttgccaaa
     8161 agttttgcac aaggttgcgg gtatttctat gttggaacat gttttccgta gtgtgggagc
     8221 tatccaacct gaaaagacag taacagttgt aggacacaag gcagaattgg ttgaggaggt
     8281 cttggctgga cagacagaat ttgtgactca atctgaacag ttgggaactg gtcatgcagt
     8341 tatgatgaca gaacctatct tagaaggttt gtcaggacac accttggtca ttgcaggaga
     8401 tactccttta atcactggtg aaagcttgaa aaacttgatt gatttccata tcaatcataa
     8461 aaatgtggcc actatcttga ctgctgaaac ggataatcct tttggctatg gacgaattgt
     8521 tcgtaatgac aatgctgagg ttcttcgtat tgttgagcag aaggatgcta cagattttga
     8581 aaagcaaatc aaggaaatca acactggaac atacgtcttt gacaacgagc gtttgtttga
     8641 ggctttgaaa aatatcaata ccaataacgc tcaaggcgaa tactatatta cagacgtcat
     8701 tggtattttc cgtgaaactg gtgaaaaagt tggcgcttat actttgaaag attttgatga
     8761 aagtcttggg gtaaatgacc gtgtggcgct tgcgacagct gagtcagtta tgcgtcgtcg
     8821 catcaatcat aaacacatgg tcaacggtgt tagctttgtc aatccagaag caacttatat
     8881 cgatattgat gttgagattg ctccggaagt tcaaatcgaa gccaatgtta ccttgaaagg
     8941 gcaaacgaaa attggtgctg agactgtttt gacaaacggt acttatgtag tggacagcac
     9001 tatcggagca ggagcggtca ttaccaattc tatgattgag gaaagtagtg ttgcagacgg
     9061 tgtgacagtc ggtccttatg ctcacattcg tccaaattca agtctgggtg cccaagttca
     9121 tattggtaac tttgttgagg tgaaaggatc ttcaatcggt gagaatacca aggctggtca
     9181 tttgacttat atcggaaact gtgaagtggg aagcaacgtt aatttcggtg ctggaactat
     9241 tacagtcaac tatgacggca aaaacaaata caagacagtc attggagaca atgtctttgt
     9301 tggttcaaat tcaaccatta ttgcaccagt agaacttggt gacaattccc tcgttggtgc
     9361 tggttcaact attactaaag acgtgccagc agatgctatt gctattggtc gcggtcgtca
     9421 gatcaataaa gacgaatatg caacacgtct tcctcatcat cctaagaacc agtaggagcc
     9481 tatcatggag tttgaagaaa aaacgcttag ccgaaaagaa atctatcaag gaccaatatt
     9541 taaactggtc caagatcagg ttgaattacc agaaggcaag ggaactgccc gacgggattt
     9601 gattttccac aatggggctg tctgtgtttt agcagtaacg gatgaacaaa aacttatctt
     9661 ggtcaagcag taccgcaaag ctatcgaggc tgtctcttac gaaattccag ccggaaaatt
     9721 ggaagtagga gaaaacacag cccctgtggc agctgccctt cgtgaattag aggaagaaac
     9781 agcctataca gggaaattag aactcttgta cgatttttat tcagctattg gcttttgtaa
     9841 tgagaagtta aaactatatt tagcaagcga tttgacaaaa gtggaaaatc cgcgtccgca
     9901 ggatgaggat gaaaccttgg aagtccttga agtgagctta gaagaagcga aagaattaat
     9961 ccaatcaggt catatctgtg atgccaagac aattatggct gttcagtatt gggagttgca
    10021 gaaaaaatag aggaggtcag tatgggtaaa tctttattaa cggatgaaat gattgaaaga
    10081 gctaatagag gcgaaaaaat ttcaggtcct cctttgctag atgataatga ggaaactaag
    10141 attttaccaa cctcttcttc ccgttttggt tatgccaatc ctaaggatca tggttttagc
    10201 caggaaacct tgaagattca ggtcgaacca tctattcata aaagccgtcg tattgaaaat
    10261 accaagagaa atgtcttcaa ttctaagttg aataaaatct tatttgcggt catctttctc
    10321 ttgattttgc ttgttttagc aatgaaactt ttgtaataga aaaggaattg aaatgaaaat
    10381 aggaattatt gctgctatgc cagaagaact ggcttatctg gtccagcatt tagataatac
    10441 ccaggagcaa gttgttttgg ggaataccta tcatacagga accattgctt ctcatgaagt
    10501 cgttcttgta gaaagtggaa ttggtaaggt catgtctgct atgagtgtgg cgattttggc
    10561 tgatcatttc caggtggatg cccttattaa tacgggttca gctggggcag tagcagaagg
    10621 tatcgctgtt ggggatgtcg tgattgctga caaattagcc tatcatgacg tggatgtcac
    10681 agcttttggc tatgcttatg gacaaatggc gcaacaaccg ctttatttcg aatcagacaa
    10741 aacctttgtt gctcaaatcc aagagagttt atctcaattg gaccaaaact ggcatcttgg
    10801 tttgattgct acaggagata gttttgttgc aggaaatgac aagatagaag cgattaagtc
    10861 ccatttccca gaagttttag ccgtggagat ggagggggca gctattgctc aagcagcgca
    10921 tgccctcaat ctcccagtct tagtcatcag agctatgagt gacaatgcca accatgaagc
    10981 aaacatcttt tttgatgagt ttattatcga agctggacgt cgctctgccc aagtcttgtt
    11041 gacctttttg aaggctttag attaagcgga aatttgacag tttttctagc ttatgataag
    11101 atttaagtaa agaaaagcta gaaaacgttt cagaggatat tatgagtatt gaaatgaccg
    11161 tcagtgagat tgcagaggtc ttaggattat ctcgccaagc aatcaataac cgtgtcaaag
    11221 aattaccaga agaagacaca gataaaaatg acaaaggggt aacagttgtt accagaagtg
    11281 gcttgattaa gctagaagaa atctataaaa aaacgatttt tgaagatgag cctgtcagtg
    11341 aagatgtcaa acaacgtgaa ctgatggaga ttctagtgga tgagaagaat gcagaaattc
    11401 ttcgtcttta tgaacaatta aaagccaagg atcgtcagtt atcagaaaaa gacgagcaga
    11461 tgcgtatcaa agaccgtcag attgctgaga aagacaaaca attagatcag caacaacaat
    11521 tgacccttca agccatgaag gatcaagaaa atcttaagct agagctggac caagcaaaag
    11581 aagaagtcca atccactaag aaaggctttt ttgctcgttt atttggagga taatcaagga
    11641 gctgtttagg ttaaatgcta acctgatggc ttcttttgtt tgtgaatagt atagttgatt
    11701 agaacagaga cagtagagga gaggtacaga atggaacgat tagaagatta cattgctttt
    11761 gacttagaat ttaatcagca cgaaggacaa acacacttga ttcaagtatc ggcagtgcgt
    11821 tttagagatg gtcgggaaat cgatgcctat gattcctatg ttcataccag cgtccctcta
    11881 aaaagcttta tcaatggttt gaccgggatt acagctgaga ccttaaaaga tgctcctcca
    11941 gttgagaaag tcttagaaga attccaagag tttgtgggtt ctttgctgat gataggctac
    12001 aatgctgcta aaagtgattt acctatttta gcagagcatg gtttagacta tagccaacag
    12061 tacaaggtgg atttgtatga tgaagctttt gaacgtcgga gttcagattt acatggtatt
    12121 gccaatctca aattgcaaac tgttgcctca tttcttggat ttcaaggtca gtctcataat
    12181 agtttagagg atgctcggat gacggcgcgt gtttacgaat ccttcttaga gtcggatcaa
    12241 gctagggaat tgttagagac agaaagtagc ttatcaaaca atccttttgg tgtcttggac
    12301 ttgtctcaat tatttgacta ggagtgccta tgaaacctga aaaacctaaa aaattgggtc
    12361 ttaaacagat ttacctcaat cttgataaaa tcctctttct atttttcttg atttttatga
    12421 tagtggagta tttgtgggta ccattcaatt catggttggc tagcttctta ttagatcaga
    12481 caggttatct ttttatttcc tataacaatg tcttagccat ccttactcat tctccattga
    12541 ttagtctagc ttttttagcc ttgattgtaa ttaaccttct ggttgcttat tttcaaatag
    12601 gactcctctt tattggtgct cgtcatctcc tctataatga aaagcgaagg ctaattgagt
    12661 atatccgcaa ggttttccat gaaagttttg gatttatgaa aaagctaact tgcgctaaag
    12721 ccttgtttat ctttttctat atagctatgc tttttccttt tatacggaaa atgctgaaga
    12781 tttattatct taataaaatc gtcattccag agtttatcca agcttattta gaagataaat
    12841 attggatgtg gtggctgagc atcctacttc tatctcttat ctttctctat gtctctgtca
    12901 gattgatgtt tgcccttccg aagattgtat atgatcagct gactgttcga gaagcagtga
    12961 tgtttagctt ggagaaaacc aagaagagag ttacttttta tgcttggaat ttattttaca
    13021 tcttgctcaa agcacattta ttattttatc ttcctttgat tcctttatta ttggctcaaa
    13081 ctttggtaga tgatatcact cagagagagt ctctgattct tggtattttg aattttgtcg
    13141 tgattaaaaa tctctattat atggctctga cttatttttt ggttaaattt gtttcatttt
    13201 tgacaggaaa ggagctggat atgcttccta ggagagaaaa agatcacatc gtgcgatggg
    13261 gtgtcatgac ttgtgccagt cttttctttg ccttagaagg ttatatttat ctggaggctc
    13321 ccatggttca tctacctcaa cttatttctc accgaggggt ttccaatgca aatgggattc
    13381 aaaatacagt agagtccttg gaaactacag cacaactcaa accagacttg gtggagacgg
    13441 acgtgcagga aacaaaagat gggcagtttg tcatgatgca tgatgctaac ttgaaaaatc
    13501 tagcaggtat caataaaagt cctcaagact taaacttgga ggagcttaaa gggattgata
    13561 tttttgaaaa tggctaccag actaaaattt caagctttga agattatctc agtcgagcca
    13621 acgaacttgg tcaaaaatta ctaattgaaa ttaaaaccag taaaaaagat agtccagaca
    13681 tgatgaaccg ctttttagcc cgttatgctg caaagctcaa gatttatgga catcaaatcc
    13741 agtctttaga ctaccatgtt gtcgaaaaag taagacagta tgatgccgaa ctgccagttt
    13801 atttcatcat gccctacaat tctgtctttc ctaaaacaag agcgacagga tatactatgg
    13861 agtactcaac cttggatgaa tattttgtaa gcaaactatg gacaacggat cagaaacttt
    13921 atgtctggac tgtcaatgat tcagaagcta tcagcaaatc tcttcactta ggagtagatg
    13981 gagtgattac agatgatttg gaaaaagttc agcgggaaat agaagtagcc caagaagatc
    14041 cagaatatac ggatttgctc ttgaaaaaag cattggaatt ctttgaattt tagtaataaa
    14101 aaagaggaac ggttgttcct cccatgatag gtaagtattc ttgtgaatgc ttgctttttt
    14161 gtggttgcaa tccgtttacg agaattgttt gtattgttct tgtttcaatt tactttatag
    14221 tgctttgaag ttggaatgct acactataac ttct
//
LOCUS       DAVAZV010000055        14210 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVAZV010000055 DAVAZV010000000
VERSION     DAVAZV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14210
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.055"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..193
                     /locus_tag="VQT46_001711"
     CDS             <1..193
                     /locus_tag="VQT46_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371691.1"
                     /translation="LKPLTVEDKAYNHALSKERSKVENIFAKVKTFKMISTTYRNHRK
                     HFGLRMNLIAGIINHELGF"
     gene            complement(529..2220)
                     /locus_tag="VQT46_001712"
     CDS             complement(529..2220)
                     /locus_tag="VQT46_001712"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET2371692.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            2356..2802
                     /gene="argR"
                     /locus_tag="VQT46_001713"
     CDS             2356..2802
                     /gene="argR"
                     /locus_tag="VQT46_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET2371693.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            2853..5387
                     /gene="mutS"
                     /locus_tag="VQT46_001714"
     CDS             2853..5387
                     /gene="mutS"
                     /locus_tag="VQT46_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET2371694.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            5534..7228
                     /gene="patA"
                     /locus_tag="VQT46_001715"
     CDS             5534..7228
                     /gene="patA"
                     /locus_tag="VQT46_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET2371695.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDVPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(7558..7827)
                     /locus_tag="VQT46_001716"
                     /pseudo
     CDS             complement(7558..7827)
                     /locus_tag="VQT46_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            8019..9785
                     /gene="patB"
                     /locus_tag="VQT46_001717"
     CDS             8019..9785
                     /gene="patB"
                     /locus_tag="VQT46_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET2371696.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            9924..10613
                     /locus_tag="VQT46_001718"
     CDS             9924..10613
                     /locus_tag="VQT46_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2371697.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLDEL"
     gene            10617..10796
                     /locus_tag="VQT46_001719"
     CDS             10617..10796
                     /locus_tag="VQT46_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371698.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            10783..12132
                     /locus_tag="VQT46_001720"
     CDS             10783..12132
                     /locus_tag="VQT46_001720"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET2371699.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWGTFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            12256..13716
                     /locus_tag="VQT46_001721"
     CDS             12256..13716
                     /locus_tag="VQT46_001721"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET2371700.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            13730..14164
                     /locus_tag="VQT46_001722"
     CDS             13730..14164
                     /locus_tag="VQT46_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET2371701.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNTYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         4167 a         2742 c         3202 g         4099 t
ORIGIN      
        1 actcaagcca ctaacagttg aagataaagc ctataaccat gcgctatcca aggagagaag
       61 caaggttgag aacatctttg ccaaagtaaa aacgtttaaa atgatttcaa caacctatcg
      121 aaatcatcgt aaacacttcg gattacgaat gaatttgatt gctggcatta tcaatcatga
      181 actaggattc tagttttgca ggaagtctat tatttggtta ggtgaattag tgaagcgttt
      241 aggcaagtgt ctctggttac gacgtcatgg actctaaatc gattatattt aggggtcatg
      301 actagtgaag cagttagcta gttcgcatat aagcggctag cgtctaacaa ttaggaactt
      361 tagttccaat aactttaaga ttacgacgtt ttaggacata aatcgatcat atttatgtcc
      421 taaaactagt gaagtatgtc ctaaaactag tgaagcgcct agccaaagtc cgaataggat
      481 ttggcgttag ttacttagat tgctttgcaa tcaagtaact ttggcgattt acatcttctc
      541 tggcgcttct actccaagca agcgaagggc ttctttgaga acgactgcgg ttgcgtagct
      601 gagggctaga cggctgtcgc gttctgggct ttcatccaag atacgtgtat gtgcatagta
      661 tttgttaaag gattgagcca ggctaattgc aaatttagca atgatagaag gttcaaagtt
      721 atctgccgca cggttgataa tacgtgggaa gtcttgaatg agtttaatga tttcccagct
      781 ttcagtatca ttcaagctat agttgccagc tgtttctggt ttgaaatcgg ctttgcgtaa
      841 gatagattgg atacgagcgt aggcatattg aacgtaaggt ccagtttcac cctcgaagga
      901 taccatagcc tctaggtcga agtcgtatcc atttgtacgg tcggttttga ggtcatagaa
      961 tttaatggct ccaaccccaa cagcatgtgc tacttggtct ttgttttcta gttcaggatt
     1021 tttagcctcg atttggacct tggcacggct aacagcctct gcaacagtag gctctagcaa
     1081 gatgacattc cctttacgag tagagagttt cttcccttct tttgtaacca aaccaaaagg
     1141 aacgtgagta atgtcgtcac tccagtcgta gcccatctct tgcaagacag ctttgagctg
     1201 tttaaagtgg gcagattgtt cttgaccaac gacatagata gatttagcaa attggtattc
     1261 gtttttacgg tagagggctg cagccaagtc acgtgtgata tagagagttg caccatcaga
     1321 cttcttgatg agggctggat gttcaattcc gtatttctca agattcacaa cttgggcacc
     1381 ttctgattca agaagtagtc ctttttcaga aagaatgtct acaactgcat ccatcttatc
     1441 attgtagaag gcttctccgt tatagctgtc aaattcaacc ttcaattcat tgtaaaggcg
     1501 gttaaattcc actaaacttt catcgcggaa ccattgccaa agagcgagag cttcctcatc
     1561 tccattttca agtttacgga accattcgcg cgcttcttca tccaagctag ggtcattttc
     1621 agcttcagcg ttgatgcgga catagagttt aaggagttca tcgattggat gagcttttac
     1681 agcttcttcg tcgccccatt ttttgtaggc aacaatcaac atcccaaatt gtttacccca
     1741 gtctcccaaa tggttgacct tgaccgtttg ataaccgatt ttttggaaaa tatgtgacaa
     1801 gctatctccg ataacagttg aacgcaggtg gccaatagaa aatggtttag cgatattcgg
     1861 actagacatg tcgataacaa cattttcttg tttaccaata ttttggtcag catagtgttc
     1921 tttttcagtg gtaacagctt gcaatacttg agcagaaatg gcagatttat caaggaaaaa
     1981 gttaacgtaa ggtcctgttg cgacaacttt ttcaaaggct tggctgttca ttttttcagc
     2041 cagttcagcc gcaatcattt gtggtgcttt acgttcgact ttggcaagag aaaaagcagg
     2101 gaaagcgatg tcacccattt ctgagttttt aggggtttcc agtaacttta aaatagcctc
     2161 ttggtccagg ctatcaatga tgctagccaa ttcgctagca atcaattctt ttgtattcat
     2221 taagagctcc tttttggact tttctactat tttatcacaa ttttaaagaa agaagaaaaa
     2281 atttttgaaa tctcctgttt ttttggtata atatggttat aaatatagtt ataaatatgc
     2341 acgcaagagg attttatgag aaaaagagat cgtcatcagt taataaaaaa aatgattact
     2401 gaggagaaat taagtacaca aaaagaaatt caagatcggt tggaggcgca caatgtttgt
     2461 gtgacgcaga caaccttgtc tcgtgatttg cgcgaaatcg gcttgaccaa ggtcaagaaa
     2521 aatgatatgg tgtattatgt actagtaaat gagacagaaa agattgattt ggtggaattt
     2581 ttgtctcatc atttagaagg tgttgcaaga gcagagttta ccttggtgct tcataccaaa
     2641 ttgggagaag cctctgtttt ggcaaatatt gtagatgtaa ataaggatga atggatttta
     2701 ggaacagttg ctggtgccaa taccttattg gttatttgtc gagatcagca cgttgccaaa
     2761 ctcatggaag atcgtttgct agatttgatg aaagataagt aaggtcttgg gagttgctct
     2821 caagacttat ttttgaaaag gagagacaga aaatggcgat agaaaagcta tcacccggca
     2881 tgcaacagta tgtggatatt aaaaagcaat atccagatgc ttttttgctc tttcggatgg
     2941 gtgattttta tgaattattt tatgaggatg cggtcaatgc tgcgcagatt ctggaaattt
     3001 ccttaacgag tcgcaacaag aatgccgaca atccgatccc tatggcgggt gttccctatc
     3061 attctgccca acagtatatc gatgtcttga ttgagcaggg ttataaggtg gctatcgcag
     3121 agcagatgga agatcctaaa caagcagttg gggttgttaa acgagaggtt gttcaggtca
     3181 ttacgccagg gacagtggtc gatagcagta agctggacag tcagaataat tttttggttg
     3241 ccatagaccg cgaaggcaat caatttggcc tagcttatat ggatttggtg acgggtgact
     3301 tttatgtgac aggtcttttg gatttcacgc tggtttgtgg ggaaatccgt aacctcaagg
     3361 ctcgagaagt ggtgttgggt tatgacttgt ctgaggaaga agaacaaatc ctcagctgcc
     3421 agatgaatct ggtactctct tatgaaaaag aaagctttga agaccttcat ttattggatt
     3481 tgcgattggc aacggtggag caaacggcat ctagtaagct gctccagtat gttcatcgga
     3541 ctcagatgag ggaattgaac cacctcaaac ctgttatccg ctacgaaatt aaggatttct
     3601 tgcagatgga ttatgcgacc aaggctagtc tggatttggt tgagaatgct cgctcaggta
     3661 agaaacaagg cagtcttttc tggcttttgg atgaaaccaa aacggctatg gggatgcgtc
     3721 tcttgcgttc ttggattcat cgccccttga ttgataagga acgaatcgtc caacgtcaag
     3781 aagtagtgca ggtctttctc gaccatttct ttgagcgtag tgacttgaca gacagtctca
     3841 agggtgttta tgacattgag cgcttggcta gtcgtgtttc ttttggcaaa accaatccaa
     3901 aggatctctt gcagttggcg actaccttgt ctagtgtgcc acggattcgt gcgattttag
     3961 aagggatgga gcaacctgct ctagcctatc tcatcgcaca actggatgca atccctgagt
     4021 tggagagttt gattagcgca gcgattgctc ctgaagctcc tcatgtgatt acagatgggg
     4081 gaattatccg gactggattt gatgagactt tagacaagta tcgttgcgtt ctcagagaag
     4141 ggactagctg gattgctgag attgaggcta aggagcgaga aaactctggt atcagcacgc
     4201 tcaagattga ctacaataaa aaggatggct actattttca tgtgaccaat tcgcaactgg
     4261 gaaatgtgcc agcccacttt ttccgcaagg cgacgctgaa aaactcagaa cgctttggaa
     4321 ccgaagaatt agcccgtatc gagggagata tgcttgaggc gcgtgagaag tcagccaacc
     4381 tcgaatacga aatatttatg cgcattcgtg aagaggtcgg caagtacatc cagcgtttac
     4441 aagctttagc ccaaggaatt gcgacggttg atgtcttaca gagtctggcg gttgtggctg
     4501 aaacccagca tttgattcga cctgagtttg gtgacgattc acaaattgat atccggaaag
     4561 ggcgccatgc tgtcgttgaa aaggttatgg gggctcagac ctatattcca aatacgattc
     4621 agatggcaga agataccagt attcaactga ttacagggcc aaacatgagt gggaagtcta
     4681 cctatatgcg tcagttagcc atgacggcgg ttatggccca gctgggttcc tatgttcctg
     4741 ctgaaagcgc ccatttaccg atttttgatg cgatttttac ccgtatcgga gcagcagatg
     4801 acttggtttc gggtcagtca acctttatgg tggagatgat ggaggccaat aatgccattt
     4861 cgcatgcgac caagaactct ctcattctct ttgatgaatt gggacgtgga actgcaactt
     4921 atgacgggat ggctcttgct cagtccatca tcgaatatat ccatgagcac atcggagcta
     4981 agaccctctt tgcgacccac taccatgagt tgactagtct ggagtctagt ttacaacact
     5041 tggtcaatgt ccacgtggca actttggagc aggatgggca ggtcaccttc cttcacaaga
     5101 ttgaaccggg accagctgat aaatcctacg gtatccatgt tgccaagatt gctggcttgc
     5161 cagcagacct tttagcaagg gcggataaga ttttgactca gctagagaat caaggaacag
     5221 agaatcctcc tcccatgaga caaactagtg ctgtcactga acagatttca ctctttgata
     5281 gggcagaaga gcatcctatc ctagcagaat tagctaaact ggatgtgtat aatatgacac
     5341 ctatgcaggt tatgaatgtc ttagtagagt taaaacagaa actataaaac caagactcac
     5401 tagttaatct agctgtagca aggagacttc tttgacaatt ctccactttt ttgctagaat
     5461 gacatcacac aaacagaatg aaaaggagct gacgcattgt cgctcccttt tgtctatttt
     5521 ttaaggagaa agtatgctga ttcagaaaat aaaaacctac aagtggcagg ccctggcttc
     5581 gctcctgatg acaggcttga tggttgctag ttcacttctg caaccgcgtt atctgcagga
     5641 agtcttaggc gccctcctta ctgggaaata tgaagctatt tatagtatcg gggcttggtt
     5701 gattggtgtg gccgtagtcg gtctagttgc tggtggactc aatgttgtcc tcgcagccta
     5761 tattgcccaa ggagtttcat ccgaccttcg ggaggatgcc ttccgtaaaa ttcaaacctt
     5821 ttcttatgct gatattgaac aatttaatgc gggaaatcta gtcgttcgaa tgacaaatga
     5881 tatcaaccag attcagaacg ttgtcatgat gaccttccag attcttttca gacttcccct
     5941 cttgttcatc ggttcgttta tcctagcggt tcaaacctta ccttctctgt ggtgggtgat
     6001 tgttctcatg gtagtcttga tttttggttt gactgctgtc atgatgggaa tgatggggcc
     6061 tcgttttgcc aagtttcaaa cccttcttga gcgcatcaat gccattgcca aggaaaattt
     6121 acgtggcgtt cgtgtggtca agtcctttgt ccaagaaaaa gagcaatttg ctaagtttac
     6181 agaggtctca gacgagcttc ttggtcaaaa cctttacatt ggttatgcct tttcagtagt
     6241 ggaacccttt atgatgttgg ttggttacgg ggcggtcttc ctctctattt ggctggtcgc
     6301 gggaatggtt cagtcggatc cgtctgttgt tggttccatc gcttcttttg ttaattacct
     6361 aagccagatt atctttacca ttgttatggt tggatttttg ggaaattctg tcagccgtgc
     6421 catgatttcc atgcgtcgta ttcgagaaat tcttgacgca gagccagcta tgaccttcaa
     6481 ggatgtccca gatgaagagt tggttggaag ccttagcttt gaaaatgtga cctttaccta
     6541 tccaatggac aaggaaccga tgctgaaaga tgtgagcttt actattgaac ctggtcaaat
     6601 ggttggtgta gttggagcga ctggtgcagg aaagtcaacc ttggctcaat tgattccacg
     6661 tctctttgat ccacaggaag gggctatcaa aatcggaggt aaggatattc gagaagtgag
     6721 tgaaggaacc ctgcgtaaaa cagtttccat cgttctccaa cgtgccattc tttttagtgg
     6781 aacgattgca gataacttga gacaggggaa gggaaatgct actctatttg aaatggagcg
     6841 cgcagccaat attgcccagg ctagtgaatt cattcatcgt atggagaaaa cctttgaaag
     6901 tccagttgaa gaacggggaa ccaatttctc tggtggacaa aaacaaagga tgtcgattgc
     6961 gcgtgggatt gtcagcaatc cacgtattct gatttttgat gattcgacct cagccttgga
     7021 tgccaaatca gagcgcttgg tgcaagaagc tttgaataag gacttgaagg ggacgacaac
     7081 cattattatt gctcaaaaaa ttagctcggt tgtccatgca gacaagatct tggttctaaa
     7141 tcaaggacga ttgattggtc aaggcacgca tgcagacttg gttgccaaca atgccgttta
     7201 ccgtgaaatc tatgaaacac agaaatgaaa gacaaactat aagaaaagtc aatagtttta
     7261 tctaaactat ttcttatttc aatttgatga tttggcgatg attttagagc acggcaaaaa
     7321 gcccttgaaa aagtccattt tttcaaaggt aatcctgtgt tgatttcaga aattacatca
     7381 ctttttgttc gtcaaatggc agctcttttt taggatataa aacagggttc ggataagttt
     7441 ttttgcaagg tggatgatgg ctacattgta atgttttcct tgttataact tagtcttaag
     7501 ataggcctta aaagcaggtg aaaagtgagg gcatgctttg gcagcttgta tgagtaccta
     7561 ccgcagatga ggggaacccc gtttgaccat tcttccagct aaatcaatct gacctgactg
     7621 ataaatagaa gaatccagtc cagcgaaagc ttgtaattga gcaggattat caaaggcatg
     7681 aatatttcga atctcggcta aaatgaccgc ccctaaacga ttcccaatcc cagtaaccgt
     7741 cgtgatgacc gagttgaact cagccatcaa gtcattgaca catttttccg ccttgtcaat
     7801 gagcctcttg taatgtttga tgatttcatt acacgagata aaacgtctat gcgttatcaa
     7861 actcattacc aattaaaaca aaaagctgtg gttagatcct ttcggaaatc gtcaagcgat
     7921 tggaggaaat gaactaatcc acagcggctt attccaagta taccacttgg gctttggcag
     7981 tagctaactg cgctaaatat aatataagga ggagtaaaat gaagacagtt caattttttt
     8041 ggcattattt taaggtctac aagttctcat ttgtagttgt catcctgatg attgttctgg
     8101 cgacttttgc ccaagccctc tttccagtct tttctggaca agcggtgacg cagctagcca
     8161 atttagttca agcttatcaa aatggcaatc cagaacttgt atggcaaagc ctatcaggaa
     8221 tcatggtcaa tcttggcctg ctggttttgg ttctatttat ctctagtgta atatacatgt
     8281 gtctcatgac gcacgtgatt gcagaatcga ccaacgagat gcgcaaaggc ctctttggta
     8341 agcttgctca gttgacggtt tctttctttg accgtcgaca agatggcgat atcttgtctc
     8401 attttaccag tgatttggat aatatcctcc aagcctttaa cgaaagcttg attcaggtca
     8461 tgagcaatat tgttttatac attggtctga ttcttgtcat gttttcgaga aatgtgacgc
     8521 tggctctcat caccattgcc agcaccccat tggctttcct tatgctgatt ttcatcgtga
     8581 aaatggcacg caaatacacc aacctccagc agaaagaggt agggaagctc aacgcctata
     8641 tggatgagag catctcaggc caaaaagccg tgattgtgca aggaattcaa gaggatatga
     8701 tggcaggatt tcttgaacaa aatgagcgcg tgcgcaaggc aacctttaaa ggaagaatgt
     8761 tctcaggaat tcttttccct gtcatgaatg ggatgagcct gattaataca gccatcgtca
     8821 tctttgctgg ttcggctgta cttttgaatg ataagtctat tgaaacaagt acagccctag
     8881 gtttgattgt tatgtttgca caattttcac agcagtacta ccagcctatt atccaagttg
     8941 cagcgagttg gggaagcctt cagttggcct ttactggagc tgaacgaatt caggaaatgt
     9001 ttgatgcaga ggaggaaatc cgacctgaaa aggctccaac cttcactaag ttgcaagaaa
     9061 gtgttgaaat cagtcatatc gatttttcat acttgcctga taaacctatt ttgaaagatg
     9121 tcagcatttc tgcccctaaa ggccagatga cagcagttgt tgggccgaca ggttcaggaa
     9181 aaacgactat tatgaacctc atcaatcgct tttatgatgt tgatgctggt ggtatttatt
     9241 ttgatggtaa agacattcgt ggctatgact tagatagtct tagaagcaag gtgggaattg
     9301 tattgcaaga ttcggtcttg tttagcggaa cgattcgaga caatatccga tttggtgtgc
     9361 cagatgctag tcaggaaatg gttgaggtag cagcaaaagc aacccacatt cacgactata
     9421 tcgaaagttt gcctgataag tacgatactc ttattgatga tgaccagagc atcttttcaa
     9481 cagggcagaa gcaattgatt tcaatcgctc gaaccctgat gacagatcca gaagttctca
     9541 ttctcgatga agcaacttca aacgtagata cggtgacaga aagcaagatt cagcatgcca
     9601 tggaggtggt tgtagcaggt agaactagtt tcgtcattgc ccaccgcttg aaaaccattc
     9661 tcaatgcaga tcagattatt gtccttaaag atggagaagt cattgaacgt ggtaaccacc
     9721 atgaactttt gaagctaggt ggcttttatt cagaactcta tcacaatcaa tttgttttcg
     9781 aataagaaag aagttgtcct atgtgggcag ctttttcttg tccataaaaa atgtttatca
     9841 cagccttaaa aaaaacatat tagacgaaag tcattttgag tgatatgata ggactatcgt
     9901 tagcattcga aaggagaggc atcatggcta gaacggttgt aggagttgct gcaaatctat
     9961 gtcccgtaga cgcagaaggc aaaatcattc attcatctgt atcttgtaga ttcgcagaga
    10021 tcattcgtca agtcggtggt ctccctttag tcattcctgt tggtgatgag tcagttgtac
    10081 gtgattatgt ggaaatgatt gacaaactca ttttgacagg aggccaaaat gttcatcctc
    10141 agttttatgg agagaaaaag accgtcgaga gcgatgatta caatctggtc cgtgacgaat
    10201 ttgaattggc actcttgaag gaagcgcttc gtcagaataa accaattatg gcaatctgtc
    10261 gcggtgtcca acttgtcaat gttgcctttg gtggaaccct caatcaagaa atcgaaggtc
    10321 actggcaagg actacctttc gggacatctc actctattga gacagtagaa ggaagcgtgg
    10381 tggctaagct atttgggaaa gaaagtcagg tcaactcagt ccatcgtcaa agcattaaag
    10441 atttggcacc taatttccgt gtaactgcta ttgattcaag agaccaaact attgaagcga
    10501 ttgagtctat cgacgagcac cgcattatcg gtttacagtg gcatccagag tttctggtta
    10561 atgaagaaga tggcaattta gaattatttg agtatttatt ggatgaactg taacaattgg
    10621 aacatctggt cgttctttct tttatttttt caaaattttt agaatgtggt attttacgca
    10681 aacgtttgaa ttctgataaa aattggagaa attcgacaaa aaaacttgaa aaaaacgaag
    10741 gtaagcgtta tgatagaaaa gaagaaatat tggaggaaga acatgtcaca tattaaattt
    10801 gattattcaa aagttttaga caaatttgtt gcaccacatg aagtggaata catgcaatca
    10861 caagtaacag cagcagatga attgatccgt aaaggaactg gtgctggtag cgacttcttg
    10921 ggatggttgg accttcctga aaaatacgac cgcgaagaat ttgaccgcat cttgaaagct
    10981 gctgagcaaa tcaagtcaga cagcgatgtt ttggttgtga tcggtattgg tggatcttac
    11041 cttggtgcaa aagcagcaat cgacttcttg aatcaccatt ttgctaactt gcaaacaaaa
    11101 gaagaacgca aagctccaca aatcctttac gcaggaaact caatctcatc tacttacctt
    11161 gctgacttgg tagagtatgt tgcagacaaa gacttctcag taaacgtaat ttctaaatca
    11221 ggtacaacaa ctgaaccagc gattgctttc cgtgtcttta aagaactctt ggttaagaaa
    11281 tacggtcaag aagaagctaa caaacgtatc tatgcaacaa ctgaccgcca aaagggtgct
    11341 gttaaggttg aagcagacgc taacggttgg ggaacatttg ttgttccaga tgatatcggt
    11401 ggacgcttct cagtattgac agccgttggt ttgcttccaa tcgcagcatc aggagctgac
    11461 ataaaagctc ttatggaagg tgcgaatgca gctcgcaaag actacacttc agacaaaatc
    11521 tctgaaaacg aagcttacca atacgcagct gttcgtaaca tcctttatcg taaaggctat
    11581 gcaactgaga tcttggtaaa ctatgagcca tcacttcaat acttctcaga atggtggaaa
    11641 caattggctg gtgaatcaga aggaaaagac caaaaaggta tctacccaac ttcagccaac
    11701 ttctcaactg acttgcactc acttggtcaa tttatccaag aaggaactcg tatcatgttt
    11761 gaaacagttg tccgtgttga caaacctcgt aaaaacgtgc ttattcctac tttggaagaa
    11821 gaccttgacg gacttggtta ccttcaagga aaagacgttg actttgtaaa caaaaaagca
    11881 actgacggtg ttcttcttgc ccacacagat ggtgatgtac caaacatgta tgtgactctt
    11941 ccagagcaag acgctttcac tcttggttac actatctact tcttcgaatt ggcaattgcc
    12001 ctttcaggtt acttgaatgc tatcaaccca tttgaccaac caggtgttga agcttataaa
    12061 cgtaacatgt ttgcccttct tggaaaacca ggatttgaag aattgagcaa agaacttaac
    12121 gcacgtctat aatagaagaa aagagtggtt tgcccactct ttttactctc tttatccata
    12181 gaaattggac tcagccaaga cttgtgatat aatatagaaa gcaaaaaggc agacgcctag
    12241 ataataggag aaactatgtc aaaagatatc cgcgtacgtt acgcaccaag tccaacagga
    12301 ctactacaca taggaaatgc tcgtacagca ttgtttaatt acttgtatgc gcgccatcat
    12361 ggtggaacat ttctcatccg tatcgaagat actgaccgta aacgccatgt cgaggatggt
    12421 gaacgttcac aacttgaaaa ccttcgctgg ttaggcatgg attgggatga aagtccagaa
    12481 tcacatgaga attatcgcca gtctgagcgt ttggacttgt atcaaaaata catcgaccaa
    12541 ctattagctg aaggaaaagc ctacaaatct tacgttacag aagaagagtt ggcagctgaa
    12601 cgtgaacgtc aagaagtagc tggcgaaaca ccacgctaca tcaatgaata ccttggtatg
    12661 agtgaagaag aaaaagcagc ttacatcgca gaacgtgaag cagcagggat catcccaact
    12721 gttcgtttgg ctgtcaatga gtcaggtatc tacaagtggc atgatatggt caaaggcgat
    12781 atcgaatttg aaggtggcaa tatcggtggt gactgggtta tccaaaagaa agacggttac
    12841 ccaacttaca actttgccgt tgttatcgat gaccacgata tgcaaatctc tcatgttatc
    12901 cgtggagatg accatattgc taatacacca aaacagctta tggtctatga agctcttggt
    12961 tgggaagctc cagagttcgg tcacatgacc ttgattatca actctgagac tggtaagaag
    13021 ttatctaaac gtgatactaa tacacttcaa tttatcgaag attaccgaaa gaaaggttac
    13081 cttccagaag cagtctttaa ttttattgct cttcttggtt ggaacccagg tggtgaagat
    13141 gagattttct ctcgtgaaga actcattaaa ctttttgatg aaaaccgcct cagcaagtca
    13201 ccagcagcct ttgatcagaa aaaactagac tggatgagca atgattatat caagaatgca
    13261 gaccttgaaa ccatctttga aatggcaaaa ccattcttag aggaagcagg ccgtttgact
    13321 gacaaggctg aaaaattagt tgagctctat aaaccacaaa tgaaatcagt agatgagatt
    13381 atcccattga cagatctttt cttctcagat ttcccagaat tgacagaagc agagcgcgaa
    13441 gtcatgacgg gtgaaacagt tccaacagtt cttgaagcat tcaaagcaaa acttgaagcg
    13501 atgacagatg ataaatttgt gacagaaaat atcttcccac aaattaaagc agttcaaaaa
    13561 gaaacaggta ttaaagggaa aaatcttttc atgcctattc gtatcgcagt ttcaggcgaa
    13621 atgcatgggc cagaattacc agatacaatt ttcttgcttg gacgtgaaaa atcaattcag
    13681 catatcgaaa acatgctaaa agaaatctct aaataaagag gatacaataa tggacatctg
    13741 ggaaaagatg tacgaagaag cacagaaact atacaatcca catgaagtat cagactttgt
    13801 ttatgccaat catgttgtag ctgcagtaga agcagaagat ggacaaatat ttacaggatt
    13861 ctgtatggag ggaacctgtg gtgttttcca tctctgcgca gaacgggcgg ccctcttcaa
    13921 tacgtaccaa ttttcaggac aaactaaggt taagaaagta ttagcctttc gagacaaacc
    13981 accttatggt ggaagttcag ccatgccttg cggtgcttgt agagaattcc ttttagagct
    14041 taatgctgaa aataaagatg cagaattcat gatggactat aatataagaa aaacagttaa
    14101 agtcgcagaa ctaatccctt attggtgggg agaagaacgt gcttctaagt ttaatgagcg
    14161 atagaagagt cagtataatt ctggcttttt ttactataag ttgaaaaaat
//
LOCUS       DAVAZV010000056        13713 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVAZV010000056 DAVAZV010000000
VERSION     DAVAZV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13713
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.056"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            2..1242
                     /locus_tag="VQT46_001723"
     CDS             join(2..341,341..1242)
                     /locus_tag="VQT46_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2371702.1"
                     /translation="MVKLIDRYGIEIVKKGKNRHYSSKLKQEMMDKALLEGCSQRSIS
                     LDYALPNQGMLSFWPAQYKKNGYTIVEKTRGRPAKMGRKRKKTWEEMTELERLQEENE
                     RLRTEVAYLKKFKRVRGKGRSPRARKAETVREMVSGGFRLDFLLETARLARSTYYYQL
                     KQLDGVDKDKEIKTEIQGIDNEHKGNYGYRRIHLELRNRGFVVNHKKVQRLMRILGLT
                     ARIRRKRKYSSYQGEIGKKAENLIQRQFEASRPMEKCYTDVTEFAIPNSTQKLYLSPV
                     LDGFNSEIIAYHLSTSPNLEQVKSMLEQAFTEKYYENTILHSDQGWQYQHDSYHRFLE
                     SKGIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKNFRSLENLEQAIVDYIDYYNN
                     KRIKVKLKGLSSVQYRTKSFG"
     gene            complement(1477..2085)
                     /locus_tag="VQT46_001724"
     CDS             complement(1477..2085)
                     /locus_tag="VQT46_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001165927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HET2371703.1"
                     /translation="MQIKFIDKVSNLIMLNLLYVASVVTVIAIGSGESALIATLIKIV
                     RHEESYPYRDFANSFFKDYWKNLGAALISNLPILILLFSLFFLPYIPLPIYIISILRH
                     IGVIYIILHLIATTFLIPLIGRYNNTLKNSLHNSIMLAYKHFFIAVLIRIIEIIPVLL
                     FFILQNQLLVWITLMIFILPSITKYANAFLYNFIFSKYEKLN"
     gene            2251..2421
                     /locus_tag="VQT46_001725"
                     /pseudo
     CDS             2251..2421
                     /locus_tag="VQT46_001725"
                     /inference="COORDINATES: protein motif:HMM:NF013577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
     gene            2410..3021
                     /locus_tag="VQT46_001726"
     CDS             2410..3021
                     /locus_tag="VQT46_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET2371704.1"
                     /translation="MTKDILELESQKMSSDTFIDEIKNNYLSIVESTRKLIDGRQIEL
                     AIKLIREANQILMIGVGSSGNAAREFESSLLRIGIISKTVIDTHFQLMHTALLKDNDL
                     IIAFSLSGSTKEVEETLLNAKRKNVKIISITNYSSRNIAKLSDCVLLTSKKESYLEGG
                     SLMAKASQLFIIDVICTRLSLINYEDTICKKEEIASLLSNKVE"
     gene            3738..4424
                     /locus_tag="VQT46_001727"
     CDS             3738..4424
                     /locus_tag="VQT46_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET2371705.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNQLLMAAISTFEEGKVAAESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            4425..5357
                     /locus_tag="VQT46_001728"
     CDS             4425..5357
                     /locus_tag="VQT46_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2371706.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFFFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            5368..6297
                     /locus_tag="VQT46_001729"
     CDS             5368..6297
                     /locus_tag="VQT46_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2371707.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPGAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            6311..7750
                     /locus_tag="VQT46_001730"
     CDS             6311..7750
                     /locus_tag="VQT46_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371708.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHTGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            7819..9396
                     /locus_tag="VQT46_001731"
     CDS             7819..9396
                     /locus_tag="VQT46_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2371709.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            9456..10916
                     /locus_tag="VQT46_001732"
     CDS             9456..10916
                     /locus_tag="VQT46_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET2371710.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKSNLDILFTWEFSNWITD"
     gene            10938..11393
                     /locus_tag="VQT46_001733"
     CDS             10938..11393
                     /locus_tag="VQT46_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT domain-containing protein"
                     /protein_id="HET2371711.1"
                     /translation="MNDTNKNQYFVYEFDTSFVEMSYSQFFEGYCILFSKEPYPSLSD
                     MPMEFRKEFLMEMSILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRK
                     TVVHRYDSSVFSNPEFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            11480..11885
                     /gene="cdd"
                     /locus_tag="VQT46_001734"
                     /pseudo
     CDS             11480..11885
                     /gene="cdd"
                     /locus_tag="VQT46_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221146.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
     gene            11898..12347
                     /locus_tag="VQT46_001735"
     CDS             11898..12347
                     /locus_tag="VQT46_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET2371712.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDILKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGTALFSIKLKKDMLLLLEPNDAHRTGLLVEEPLNIKKVVFKVKI"
     gene            complement(12459..13018)
                     /locus_tag="VQT46_001736"
                     /pseudo
     CDS             complement(12459..13018)
                     /locus_tag="VQT46_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            13287..13713
                     /locus_tag="VQT46_001737"
                     /pseudo
     CDS             13287..13713
                     /locus_tag="VQT46_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4855 a         1846 c         2530 g         4482 t
ORIGIN      
        1 catggtgaaa ttaattgacc gttatggcat agaaatcgtt aaaaaaggga agaatcgtca
       61 ctattcttct aaattgaaac aagaaatgat ggataaagcc ttactggaag gttgttcaca
      121 aagaagtatt agtcttgatt atgccctccc aaaccaagga atgctttcat tttggccggc
      181 acaatacaag aaaaacgggt atactattgt tgagaaaaca agagggagac cagctaaaat
      241 gggacgtaaa cggaagaaga cttgggaaga aatgacagaa ctagaacgac tccaggagga
      301 gaatgaacgc ttacggactg aggtggccta cctaaaaaag ttaaaagagt tagaggaaag
      361 ggacgaagcc ctagagcgag aaaggcagag acagttagag aaatggtttc aggaggattt
      421 cgactagatt ttcttcttga aacagcacgt ttagctcgct cgacttacta ttatcagttg
      481 aaacaactgg atggggttga taaagataaa gagattaaaa ccgaaattca gggcattgat
      541 aatgaacata aaggcaacta tggctatcgt cgaatccatt tagaactaag gaatcgtggt
      601 tttgtggtca atcataagaa agttcaacgg ttgatgagaa ttcttggttt aacggctcga
      661 attcgccgta aacggaagta ttcttcctac caaggagaga ttggcaagaa agcagagaat
      721 ctcattcaac gccagttcga agcatcgagg ccaatggaaa agtgctatac agatgtgaca
      781 gagtttgcca ttccaaatag cacacagaaa ctctatttat caccagtttt agatggtttt
      841 aacagtgaaa tcattgctta tcatctttct acttcgccaa acttagaaca agtgaagagt
      901 atgttagaac aggcctttac agagaaatac tatgagaata cgattctcca tagtgaccaa
      961 ggctggcaat accaacacga ttcttatcat cggttcctag agagtaaggg aattcaagca
     1021 tccatgtcac gcaagggcaa cagcccagac aacggcatga tggaatcttt ctttggcatt
     1081 ttaaaatccg aaatgtttta tggctatgag aagaacttta gatctttaga aaaccttgaa
     1141 caagctattg tggactacat tgattactac aacaacaaac gaattaaggt aaaactaaaa
     1201 ggacttagtt ctgtgcagta cagaactaaa tcctttggat aaattatttg tctaattttt
     1261 tggggtcagt acagtattaa ataccatgat cttatgcgtt ttataataaa aaatctgttc
     1321 ttgttttatt tttagaaaat ttactaaaga ctaaaaatat tatgaataat ttaaaaaata
     1381 gtcaggttat atagtttttt gaaattaaaa ttattttatc gttgaaatta gttaaaaatt
     1441 tttataaaat caagatgcaa ggctatgaga tgttctctag tttaattttt catacttcga
     1501 gaatataaag ttatataaaa atgcattagc atattttgtt attgagggaa gtataaaaat
     1561 cattaaagtt atccaaacta gtaattgatt ctgtaatata aagaagagta gaactgggat
     1621 aatttcaata attctaataa gaacggcaat aaaaaaatgt ttataggcta acatgattga
     1681 attgtgtaga gaatttttta aagtgttatt atatctaccg attaaaggaa ttagaaatgt
     1741 tgttgctatt aaatgaagta tgatatatat tactccaata tgtcgtaaga tagaaatgat
     1801 atatataggt aatggtatgt agggtaggaa gaacaaactg aataataaga ttaaaattgg
     1861 taaattagat attaatgctg ctcctaaatt tttccaataa tctttaaaaa aactgtttgc
     1921 gaagtctcta tagggatagg attcctcgtg tcgtacaatt tttattagag ttgctattag
     1981 ggcactttca cctgatccga tagcaataac tgttactact gacgctacat agagtagatt
     2041 taacattata agatttgaaa ctttatcaat aaattttatc tgcatcttta actcctgctg
     2101 tttttatact tataatatca catcatttga gtttcatcaa ctttgaatac attaagaaag
     2161 aatataacta tgaggaaagg aaaaaattat tatgaataaa tccaaaaaat ataaagaaag
     2221 aattcattat gaatacgata atcttactaa atcagagaaa aaattgctga ctatatttta
     2281 gttagagata gtgaaatagt ttatgaaacg tcttcagaaa ttgttagtaa agtaaaagtt
     2341 ggagagggaa ctcttaatcg attttgcaaa aagattggat actctggttt tcaggaacta
     2401 aaattaaaaa tgacgaaaga tatattagag ttagaatctc aaaaaatgag tagtgacaca
     2461 tttattgatg aaataaaaaa taattattta tctattgtgg aaagtacaag aaaattaatt
     2521 gatggtagac aaatagaatt agctataaaa ttaataagag aagcaaacca gattttaatg
     2581 attggtgtgg gttctagtgg aaatgcggct agagaatttg agagtagttt gttaagaatt
     2641 ggaataataa gtaagacggt aattgatacc cattttcaac tcatgcatac tgcgttattg
     2701 aaagataatg atttgataat agcgtttagt ttatctggtt ccacaaaaga agttgaggaa
     2761 actttattaa acgcaaaaag aaaaaatgtt aaaattattt caataacaaa ttattcgtcc
     2821 agaaatatag caaaattatc tgactgcgtt cttttgacat caaaaaaaga atcttattta
     2881 gagggtggta gtttaatggc taaggcttct caactattca taattgatgt aatatgcact
     2941 agactctctt taataaatta tgaagatact atatgtaaaa aagaagagat tgcttctttg
     3001 ctgtcaaata aagtggaata aatcaataat ttttaaattt taataaaaat tttttaaaat
     3061 aaattaaaaa acgatcctaa aagggtcgtt tttttgctaa agttttaaaa ataaacaata
     3121 attaagatta tagtgcgttg aatctatatt aggacataac aattcttaaa tcattgttag
     3181 aaattagttt gaattttcca atcaatttgt tcgattttta catcattgca ttatatcacg
     3241 tgactattaa ccttgttttc tcctaaaatt gattttcttc ttttcttatc ttgtccactc
     3301 gaaacaagta ttgtaagaat ttgattattt ttgaaagtac ttttaatata tttgagatag
     3361 ttaaaaaaga tttgaaacta aattccaaat tagaaaaaga cttgaaatgc taaaaaaaaa
     3421 aagtatactc taattgaaaa cggtaacaaa actaatttag agaatgaaat atagagtatt
     3481 tctctcttaa aagtttttgg tgaaacgaga tgtagaaagg agatttagcc aaagagtcta
     3541 ttagtgctag aataatagat tagaattata gtgtattgaa tctataacag tacgccttaa
     3601 atgctaaaat atttctataa attaatttaa ctttcctgat agggctgttc atatcttatt
     3661 tcaattcact atataaataa aattgtagta gatgttattg aattagtaaa aaaaataaaa
     3721 aaacggaggt tttctgaatg gaaactaaaa aaattaaaaa tttaaaaggt caaataattg
     3781 tttcctgcca agcgttagaa ggagagccac tttatactcc aaatggagga gtgatgccgt
     3841 tattagcaaa agccgccttt caagcaggcg ctaaaggtat tcgtgctaat tctgtccgcg
     3901 atatttcaga aataaaagaa gaagttgact taccaattat aggtatcata aaaagagatt
     3961 acgatggctt tgaacctttt atttcagcaa ctatgaaaga gattgatgaa ttagttagtg
     4021 aaggagtaga cattttagct ttggattgta ctaatcgttc aagaccaggt tatgataata
     4081 ttactgactt tattcatgat attaaagtca agtatccaaa ccaattatta atggctgcta
     4141 tttctacttt tgaagaaggg aaagtagctg ctgaatcggg agtagatttt gtgggtacga
     4201 cattatctgg ttatacacca tatagcccta aaaaagataa tcctgatttt gagttagttg
     4261 aaagattggt aaaagagctt gacgtaccag ttattgctga aggaagaata agtactccgg
     4321 aacaagctag aaaaatgtta gatttaggtg cttacgcagt ggttgttgga ggagctatca
     4381 ctcgtccttt ggaaatagcg aagaagttta ttgaggtagt ttagatgaat caagaaatat
     4441 taaaaaagag taagattcaa ttgacagttg aacatattca aaaatattgg attttatatt
     4501 taatgatgat tccagcaact gttctactaa ttttatttac gtatggacca atgtacggca
     4561 ttattatggc ctttcaagac tttactgtct tcaagggata tactggaagt ccatttgtcg
     4621 gtttaaaaca ttttcaaaga ttgttctcag atcctttgtt ttatagattg ttcaagaata
     4681 cgttcatggt aggggtttta gattttttat tctttttccc agctccgctt atttttgcac
     4741 tcatattaaa cgaagtcaga aaagtaagat ttaagagtgt agttcaatct attagttatc
     4801 ttcctcattt tattccccta gtggttatgg ttggtattat ttttgaacta tttggttcat
     4861 atggtattat taacagttta ctttcatcac ttggaatgga gccaataagt ttctttacaa
     4921 aatctgaatg gttcttgcct ctctacattg gttcaggagt atggaaaaca ataggttggg
     4981 gttctatcat ttatatggga gcattaacca atatagattc aactttatat gaagcagcag
     5041 atatggacgg ggctaataga tggcacaaaa tgtggcatgt aactctacca agtttaagac
     5101 ctacagtagt tactttgttt atactaaatg ctggtggtat catgcaagta ggatttgaaa
     5161 aggtattctt gatgtctagt cctgcaacat atgaagtatc tgatgtatta tctacttatg
     5221 tttatagaca aggtatttta aattctgatt tcagttactc agctgcagta ggattattta
     5281 ataacatagt agctttgtta tttgttttat tagctaataa gattgctaaa aaacttggcg
     5341 aagaaggaat tgtataaggg gggtaaaatg attttttcaa aaaatacaaa aaagagtaat
     5401 agagacaaag aaaccttcgt tgattatctc tttatattca ttttaataat aataacctta
     5461 cttatgttgt atccattatg gtgggtagtg atgacgtcac tttcagaacc agtttggcta
     5521 tctaaaaacg ttgttaaatt atttccctta aaaatagata ttactgcata taagtttatt
     5581 tttggggatt ctaaactatg gcaagcatat ggtaatagtg tattgtatgc tgcactatct
     5641 acaattgtta gtgttgcggt atgtagtatg tatgcctatc cacttacaat tcctgaaatt
     5701 aggggtaaaa aattctggaa tactcttatt ttgattccaa tgttctttag tggaggaatg
     5761 atcccgcttt atatacaagt tgcaaacctc ggtttattga atactgcttg ggctcttgtt
     5821 ttacctggtg ctgtttctac atattatata attttgttta gaacacagtt taaatcaatc
     5881 ccaatggagc ttcgtgagtc tgctagaatt gatggggcaa gtgaatttag aattttttgg
     5941 aatttagtat taccattatc aaaagttatt ttcatgatta tagcacttta ttgcatagtt
     6001 ggttcatgga atagttttac tcctccatta ctttatttga atgacgacac taagatgcct
     6061 ttatctattt atttgagaaa tttagtcgtt acaaatacaa ctgatactgc tgaattatca
     6121 ctttctgcag gtaatacata ttaccaacaa attgctgctc aaggtggagg tattggtatg
     6181 cgtattgcta ttaagatggg tactattgtt gttagtgtta ttccaattat gatgatttat
     6241 ccatttattc agaaacattt tgttaaggga atcctgctag gttctgtgaa aggttaataa
     6301 ggtaattatt ttgcaaaatt taaaaaaata tcttttatta gatagcggtt tagtagttgg
     6361 gtatacatta gaaaatgctc aattaaaatt aaataagcta aaaaaagata ctgaaaacaa
     6421 tccactattt ggtgaagagt attttgccga aaatcctaaa ttatgggaag ttcgttttga
     6481 taattcatat ccaaacgtta tctatgataa agaattgaaa ttatatagat gttggtatca
     6541 aacatttgtt agtgatgaag caagcgaaga gactccttta gcagaacgtg gagagaagga
     6601 atacattgtc aagtcatcta gaatgacagc actttgctat gctgaaagta aagatggagt
     6661 aaaatgggaa aaaccaaatc tcaatctagt aaaatttaaa ggttcaaaag ataataatat
     6721 tgttctgatg catgcacacg gtgcaggtat catgctagat gaacaggagt tggatcctaa
     6781 gaaacgatat aaattagttt caaaattaga attttctccg aatcttcatt acatggttgt
     6841 tgttttttca gaagacggta ttcattttga cgaacctatt ccatggaaaa aatggaatcc
     6901 tgcagcagat agtcataatt ttccatttag agatccaaaa actggtaaat acgctgttat
     6961 tacaagaacc tgggcaaata acgtacgtct aagtgcaatt actttcagtg atgattttat
     7021 taattggtca gaacctaaag aaatccttag gggagatgga tttgaagatc aaatttattc
     7081 tatgccagta atttcatacg cggatatcta tttaggtttt gcttcaatgt accatgaagg
     7141 cgacacttta aatgaaaact atgataaagt agacttagaa ttgaaattct ctgctaattt
     7201 ggaacaatgg gatagtgtat gtaagggcga ctatctcatt gaaaggggag gtggagtata
     7261 cccgcagaat gctgattttg atgctagttg tattttcacg gctgctccaa taattgaaga
     7321 tgataagatt tggttctact atatgggtgg aaatggtaat cacactggct tccgagaaag
     7381 ttcattagct agaggatata ttaagaaaga ccaatttgct tattatacta ataagagaga
     7441 aggaattcca gctaaaatat ctacagttag cttccaaact tacgatgatg aaatttatat
     7501 cttagctgat attcctgaaa atggttatat taaagttgcg gtaggtacta aatacggtaa
     7561 tgcttattca gatttcggtc aggaagatat ctctcttgtt caagtttccg atggtaagta
     7621 taagttggaa tttaataaaa aatctatctt agatttaggt aattctccag ttgcgttcaa
     7681 atttgaaatc gagaatgcaa aattgtatgg tattgaaggt agtattcagc aacactatct
     7741 caaatattaa ccagaataat tcgttaacaa ataatctcta tattagtgga gatagatata
     7801 taaaatggag gtcttattat ggtaaagctt aataaggtat taaaagggag tgttgcattc
     7861 ctgagtgcaa gtttattgct agcagcttgt ggcaataacg ctaattcaaa gcccgctgaa
     7921 aaaacagctg atggtaaaac gaaaatttcg tttctatcta catggcaaat taatgatgtt
     7981 cgtccgccta aagatgaaac acttgttggt caatggttag aagaacagct aggtattgat
     8041 attgatcttg taactattcc tggcgaggga gtaagttcta aagtaaattc tcttattact
     8101 agtaaccagt taccgactgt tttgttgaca acaggagata agagtgatat cgctggtatc
     8161 aacaaacttg gtaaacaggg tgcattctta gatttgtcac aacacatgga caaactacca
     8221 aactataaga agtaccttga aaaaaataat gcattagctc aaatagaaga tgatgaaaaa
     8281 catatttatg ctttcacaaa attctttact gatgagaata tcatgtatac tacaccaatt
     8341 ctgagaaaag acttacttgt tggttcagaa tttgaagatc tttcaaaaat taaaactgtt
     8401 gatgactata caaaagtttt gaaatatttg actgaaaaac aaggttctcc agcatttatt
     8461 caacgtaatg gctatgaagg cttcatgaag cgagttacac cattgtggaa tttaagccat
     8521 cgtacatact atgactatga atcagattca tataaacatc cagttgaaca acctcaattg
     8581 aaacaattcg ttgaatggtt gaaagaatta cgtaaagata acgtacttca ccctgactgg
     8641 gcagttatga aagatgaaac ttgggaaggt ctattggctt ctaacaaggg ttcattcact
     8701 gttgaccgta tgaatatcat tggagataat aactttgata aatcatttga ttggcagcca
     8761 cttgtttatc cagaaattaa tggaaaacgt tatttgcaac cgaaaacacc gtacatttct
     8821 gattcaggtt gggtaatcaa tgccaatgca ccaaaagaag aaattgataa agcgttagaa
     8881 ttctttaatt tcttatacgc tgatgaaaat caagaaaaac ttgctattgg atttgaaggt
     8941 aaaacattta cacgtgaaaa ccctaatact caagcaggta ttaaatggtt gattcaaatt
     9001 tacggtgaaa atgctggaaa tgataaagca gaactgctgt ttaaacatgg taaccaagca
     9061 tttactcgcg ttcaaactaa attagatatt gaggcacagc caggaacatt ccctaaagtt
     9121 atgtatgatc aagtagataa aattaagaaa gatttaggtg gttttagacc agatactccg
     9181 gttctttcct ttacaactga agaattagat gttttaacta aatctgaagc aggattaaat
     9241 actttctttg atgaaaatat tattaaattc attgaaggac aaagagatat gagtgagtgg
     9301 gattcattta tcaatgaagc taaatctaaa gacttggata aagttacaaa agtatataat
     9361 gatgcctaca aacgtgtcaa agatagaatg aaatagacta aatggtagct ctctggtttt
     9421 tcagagagct actactgcct gagggggagt aagctttgta tgatgtagta attataggtg
     9481 caggaagttc gggcgcattg gctgcaattg cttcggggcg tctagggtta aaaacttgtc
     9541 taatagagaa gggaagtaga attggtggag ttcctattaa tacactaatg gggtcatttg
     9601 ctaatctata ttttgatgat tctggtagag taaatgcaag taaaattgtt ggggaattaa
     9661 tagaacgtat tatcaaaaaa ggtggtactg tctttaactc tatggaagaa ttgatgaatg
     9721 taaatgattt ttatcagatt acaattccct atcaaccaga agtttatgaa tcggttttaa
     9781 ctgatatgtt gattgagtct aaagttgata ttttactaaa tgttgaagtt aataatatta
     9841 tttatgatag taaaaatatt aaaagtcttg aaattttaag taatcaggaa gttaaattga
     9901 ttgattctaa agtttttatt gatgctacag ggaatgcaac aattgcttct gctagtggag
     9961 ctgatgttta tgaaaaaaat tcttcttacg gttgtttaat gagagttgga ggagttgata
    10021 tctcaaagac tatagaacat attgaaaaaa caaagcagtg gaactatata gaaggatata
    10081 atcagtggtt agaagaagta ttagcaaatc gaaagtacag agccactgga gcagttttaa
    10141 aagatccagt ttcttatgat catgccccta tgctttcaaa agacgaccat tttatgaatg
    10201 atgaaaaatg gaattacatt aaagaaagat gggaaaaatt tagatttatt tacactttag
    10261 aagtatcact atttaggaat gaattaaaaa aagctgtaga atctggggat tttaattttg
    10321 aaatttatca tgatgataaa tctggagtca ctatgaatgg cgacggtata agctatggtt
    10381 catggggtca aaatgtagca ttaattaatg ttgcaaaagc atttggattc aatcccaaat
    10441 atatggaaga tgaatcacat gctaatattc tttctagaaa atataattta acatttttat
    10501 cttttcttaa aaaatatgta ccaggttttg aaaattcttt tatccttgat cagggaacta
    10561 gagctactaa cagatcatgt aggcacattg ataattcatc tatgatggac gaaattcttg
    10621 attttccaat gtatacattt aagactatgt atagctatca aactcctaaa gaaataacgt
    10681 acaaatcaat tgtaggtgga aaattgaata atttgtttgt aataggtaaa ggtgcttacc
    10741 aatccgaaag ttttagatca caaattagtt gtatgttaat ggggatatca tcagcagcag
    10801 cggcaaaaac tattattgaa gataaaagca atactctaaa cattaataga gatttgttta
    10861 aatcgaactt agatatatta tttacatggg agttttctaa ttggattact gattaacaaa
    10921 taataaggga atattaaatg aatgatacta ataaaaatca atactttgtt tatgaatttg
    10981 atactagctt tgtagaaatg tcttattctc agttttttga aggatattgt attctttttt
    11041 caaaagaacc ctatccttct ttatctgata tgccaatgga atttagaaaa gaatttttaa
    11101 tggaaatgag tatattaggt gatgcgatgc ttgaagtgtt aaatgcctat agaattaatt
    11161 atgatatctt aggaaattca acacctgtac ttcatgctca tttatttccg agatacatgt
    11221 gggaagagga agagagaaga aaaactgtag ttcatagata tgattcttca gtttttagca
    11281 atcctgagtt tgaatttact atagaaaagc atggaccaat tattaaaaaa ctgaggtctg
    11341 ctattgatag acattataga gagtatcaac aattattaga tgattcaaac tgaactccac
    11401 attttcgatt agatttaata ccttgtatat tacaactagg ttgtggatga tataattttt
    11461 tgaaaaatat attttaggaa tgacttataa agcaattata tcagaggcta ttaaatcaat
    11521 ggccaaagct tatgctcctt attctgattt taaggttgga gctgcgttag taactgaaga
    11581 taaaaaattt tttctggatg taatatagaa aatgctgctt tttctcctac ttgctgtgca
    11641 gaacgagtat ctttttataa agctgtattt aaaggagaac gttcgttttc aagaacatgt
    11701 attgtaggtg gaaaaaatgg tatcttatca tcttttatag caccttgcgg agtgtgtcgc
    11761 caggtaatga tagaatttgt aatcctgatt catttgaagt tatattggct agtgatgttg
    11821 atacttataa agtatataaa cttaaagaac tactaccagt tagttttaat caagaaaatt
    11881 tataacagga gggaactatg gaattagttg aatttaaaaa tggacatgtt aatacggttc
    11941 atgagcatat cgcaataacg aaagtaaaag agtttctaaa taatcatgat atattaaaag
    12001 ataaaggtgg catacataaa atttctactg atttctttta caatataatt gatatggaaa
    12061 ctacaactga agagaataga ccgtgggaaa gtcataagga atattatgat gtccattatc
    12121 tgttaaatgg agaagaaaca attttatata acttcttgtc tcaaatggaa ttgtctgaat
    12181 ataaagtaga tgatgattgg caacaaatga atgggacagc tttatttagt attaaattaa
    12241 agaaagatat gttacttttg ttggaaccaa acgatgcaca tagaacaggc ctattggttg
    12301 aagaaccact taatattaag aaagttgttt ttaaggtaaa aatttaactg aaagtacttt
    12361 cggggattaa gaattttaaa atatttaaga aattgtattc taaagttcta aaattataga
    12421 tatttaattt aaagcttgtt aaaatagaat agtaacactc atctgctttc aaaaagcatt
    12481 ctattccatc tccgattaac gatggacttt atcacctcct tctccagtcc ttgtatgaca
    12541 tcttggagtt gattcatgac atcttccaaa gttcgaaagg ctttattctt aaatccacgt
    12601 ttatgaatct ctttccacac ttgttcgatg ggttcatctc tggtgtgtat ggaggaataa
    12661 atgcaaaacc aatattagtc ggagtcttta aggtacttga tttatgccat atagcattgt
    12721 ccataacgag taaaagataa tcatctggat aagcttgtga aagctcttct aaaaaggcgt
    12781 tcatccactc agtattacat ccaccagcta ttaagaaaaa tgattcgcct gtatgggcat
    12841 caacagctcc ataacaatag tgaaattctc gtatatagtg actatggaca tgtggaccta
    12901 ctcctattgg agaccaacaa gatcccagtt tactgattct accgaagcca gcctcatctt
    12961 ggtacatcaa gcgaacctta tgaaaacgtc tactggtttt aaagcgcttt cttttcttca
    13021 gttgatttca tatcactatt gtataatgct ttttgatttt agtctagtat aaatagcgag
    13081 aaatatctat cctatcttct agaatgtctt ccaaacgagg aaactctcgt aaacaaagag
    13141 gttttagagg cctatttacc gtggactaaa gttgcacaag aaaagtgcaa ataagaaatc
    13201 tccagattag gaactatccg tgagttctct agtctggaga tttttcaata gacttcctgc
    13261 gaaacaaaat atggtataat agttctatga attatgaagc aagtaaacaa ctaaccgatg
    13321 cacgatttaa gcgtcttgtt ggtgttcaac gcacgacttt tgaagagatg ttagctgtat
    13381 taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa ttaagcctag
    13441 aagaccttct tatggccact cttcaatatg tgcgagaata tcgaacttat gaagaaattg
    13501 cggctgatct tggtattcac gaaagcaact tactccgtcg gagccaatgg gttgaagtaa
    13561 ctcttgttca aaggtggtgt tgcgatttca agaactcctc tcagttctga ggacacggta
    13621 atgattgatg cgacggaagt aaaaatcaat cgacctaaaa aaagaattag cgaattattc
    13681 tggtaaaaag aaatttcacg ctatgaagac tca
//
LOCUS       DAVAZV010000057        12573 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVAZV010000057 DAVAZV010000000
VERSION     DAVAZV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.057"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(251..433)
                     /locus_tag="VQT46_001738"
     CDS             complement(251..433)
                     /locus_tag="VQT46_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371713.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(649..1881)
                     /locus_tag="VQT46_001739"
     CDS             complement(649..1881)
                     /locus_tag="VQT46_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET2371714.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQT46_001740"
     CDS             complement(1910..2980)
                     /gene="gla"
                     /locus_tag="VQT46_001740"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET2371715.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(3048..4217)
                     /locus_tag="VQT46_001741"
     CDS             complement(3048..4217)
                     /locus_tag="VQT46_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET2371716.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(4403..5707)
                     /locus_tag="VQT46_001742"
     CDS             complement(4403..5707)
                     /locus_tag="VQT46_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET2371717.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(5824..6978)
                     /locus_tag="VQT46_001743"
     CDS             complement(5824..6978)
                     /locus_tag="VQT46_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2371718.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(6975..7526)
                     /locus_tag="VQT46_001744"
     CDS             complement(6975..7526)
                     /locus_tag="VQT46_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET2371719.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(7519..8655)
                     /locus_tag="VQT46_001745"
     CDS             complement(7519..8655)
                     /locus_tag="VQT46_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET2371720.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQT46_001746"
     CDS             complement(8796..9461)
                     /gene="cpsD"
                     /locus_tag="VQT46_001746"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET2371721.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGELFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQT46_001747"
     CDS             complement(9471..10163)
                     /gene="cpsC"
                     /locus_tag="VQT46_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET2371722.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYLVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(10172..10903)
                     /locus_tag="VQT46_001748"
     CDS             complement(10172..10903)
                     /locus_tag="VQT46_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET2371723.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(10905..12350)
                     /locus_tag="VQT46_001749"
     CDS             complement(10905..12350)
                     /locus_tag="VQT46_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET2371724.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         4237 a         2433 c         1656 g         4247 t
ORIGIN      
        1 aattcactta cttcatatta catttagcat gaaatgaaat aagcgaattc tactttgttt
       61 gcatacaatt aaaaatcaat tcctaaggat gttttaaata actgtgtaaa aggcataatt
      121 tcaccatttc ttagtttttc aatgctaaat tacatagtaa ctggagagct attagaaatc
      181 tctaacttcc tcatagttaa aaaatgacaa tgagatactt attgatttca attcattaac
      241 agaatacgaa ctagacaagt gagttcgtct ccttaacaaa cacttccaag cgtttacttt
      301 cctcattcag tcgtcgtaat ctacaactta catcatcaga taagtcatac tcaccattta
      361 gaatagatag aatatgttgt ttttcttctt cagtcttctc ttcaataagc acatttttaa
      421 aaattactgc cattatcagc acctcacttc gaaggaatat atgcaactat atcctattaa
      481 gtcaatctct actgacaaaa gaagtatatt tacttcacta agtgcgagcg agaatataga
      541 aatatcttta ttgttttaga tgagttgtcg ctatcctcca gctagttttt aactattcta
      601 tcattcaaat gatatagatt attagggact agaaatatac aaattgattt aatctctctt
      661 aaaaatatcc ctagtataaa ctttacccct cacatcttct aaagtctcat caaaacgatt
      721 tgcaacaatc acttgactag atttcttaaa tatttcaaaa tcattaacta cttgactacc
      781 atagaaagta gtaccacttt caagagttgg ttcgtaaata ataatagtaa caccttttgc
      841 tttcaaacgc ttcataatac cttgaataga agattgtcta aaattatctg aattactttt
      901 cattgttaaa cgataaattc ctacaacaat ctctttttct ttatctggtt tatagaaatc
      961 attgcctaca taagatccag caagatctaa aatacgatct gcaatataat cttttcttgt
     1021 ccgattactt tgtactatag ctgttatcat ttcttgtgga acgtcagaat aatttgcaag
     1081 aagttgcttg gtatctttag gaagacagta acccccataa ccaaaagaag gattattgta
     1141 gtgagaacct attctcggat ctaaacaaac tccatcaata atcgcttgag tatctagtcc
     1201 tttcatctca gaataagtat ctaactcgtt aaaataggaa acccggaggg caagataggt
     1261 attagcaaaa agttttactg cttcagcttc tgtaaaatcc atatacaatg tttcaatatt
     1321 ttctttcact gcaccttcct gaagcatttt tacaaaaatt tcagcagact ttaccaaatc
     1381 tttatcatct ttatctgtac ctataataat tcgactcgga tataggttat catataacgc
     1441 ttttgactcc cgtaaaaact caggactaaa cataatattg tctgtaagaa atttcctccg
     1501 tactgacttt gtatatccaa caggaacagt acttttaatt attataattg catcaggatt
     1561 atatttcata actgcttcaa tgacagcctc gactgaagat gtatcgaaaa aatttttttt
     1621 cggatcataa ttagttggag ccgcaataac tataaaatcc gcattctcat atgcttcctc
     1681 tgcattcaat gtagctacga gattcaattc tttttccgcg agatattttt ctatataatc
     1741 gtcttggata ggggacttct ttttattgat taactcaact ttctcaggaa tgatatctac
     1801 ggcaacaact tgatgatgtt gagccagtaa gattgcaata gataatccaa catatcctgt
     1861 acctgctact gctattttca taattttttc ctttctcaaa acactctcgt tatacattat
     1921 agtagtcttt ataccactct gcaaactttc tcaaaccttc tcgtaaagaa gtttttggtt
     1981 taaaaccaaa atctctctct aaatcacttg tatctgcata agtaacagga acatcgcctg
     2041 gttgcatagg aactaatttt ttatgactat caaaatcata attttccggc aaaactcctg
     2101 ccttgattag ctcctgttga agaacatcca caaaatctaa caaattttcg ggtttactat
     2161 tcccaatatt gtacacttta tatggggcta acggtaaatt atcagatccc actagtttct
     2221 tcggagctga ttgcatgacc cttactatcc cctcaacgat atcatctata taagtaaaat
     2281 ctcgtttaca attaccatga ttataaatct caatatcgga accacttcgc aatttatctg
     2341 taaatccaaa ataggccata tctgggcgcc cagcaggacc ataaactgta aaaaagcgta
     2401 agcctgtcga aggaatattg taaatctttg aataagcata cgcttgaagt tcatttgttt
     2461 ttttagtcgc agcatatagt gaaataggat tgtctacctt atcttctgtt gcaaacggga
     2521 tttttttatt tccaccatat accgatgagg acgatgcata aactaagtgt tccacaccac
     2581 catcatatat ctcatacgaa tgacgacaag cttccaacac attatgaaag ccaacgatat
     2641 tactttctat atatacatct ggatttgtaa tggagtagcg tactcctgcc tgggcagcta
     2701 gattaacaac aatctgagga tgataactct taaaaatctt attaataagc attttatctg
     2761 caatatcacc cttgataaat atccagtttt tttctggata atcctgaatt agcttattaa
     2821 gttgaagcaa tcgataatct ttaagtgcaa tatcatagta atcattcaaa ttgtccaaac
     2881 caatgattgt catcgttcct tctaattcca ataatttcct aaccagattt gatccaataa
     2941 aaccagctac tcctgtaatt agaattgttt ttcctctcat atcataatac ctcttgttat
     3001 ttttatattt tcgtccacta atacacattc tttaacaact attataatca atttctaaga
     3061 taatctataa taaaaaacaa accacataca gtataagaga ttgctgatgc tatcgcagct
     3121 cctgtaattt ggtagttagg aattaagtac cagtttaaac ttatatttat caaagccgac
     3181 acagataaaa tttttatagc tacactctgt ttaccctgag atatataaat tggttgtaaa
     3241 attttaaaga aaatcatcga taagcttcct aaaaaaatga ctaatgttat aggaaatgcc
     3301 tttatataac tggaaccata aaggagcgta atcgcaaatt ctccaaaaga aagaaatcca
     3361 ataattaata aaatcataaa tagaaatgat acttttattg catttattgc tttatttttc
     3421 tcaaaagttc ttttagccga atcaccaaat aaaatctctt taaatgagtc tggaaccatc
     3481 aaaaacatat tagaaaacgt aactgcgaca ctgtatatac ctacattata actactagac
     3541 atttgcttca acattatgat atcaatacta taattaaatg taattaatag agtaagaatc
     3601 atagaaagaa atccaaactt atatatagtg aaaaattctt taatactaat atgttcaaaa
     3661 actgggaaca tattgtaata gtataaaaat aaaatgatac gtaaaaattc attaatagca
     3721 tataccaaaa ataccatctc tatagaaact aaatgaaata gtaacaacaa tactagcata
     3781 acggaatata ctacgcttac tcctaataca atcttattcc tctttatact attttctatt
     3841 actgcaatca tagtaagatt tgttctcata atagatagac tggacaaaac tattattacc
     3901 ccaccataat ctatcggaac atcagctaaa actattatta aacctattat tccaaacaat
     3961 aatccttgaa taaaagttaa aaaaacaaat ttattctgat actcattaga atgattcctt
     4021 ttaaaggtcg agtaagcctg acctaaacca actccaccta aaatataaaa aatttctact
     4081 aagttcatta cataggcata atctcctttt ttttcaacac ctaatcccct attaattata
     4141 attgaggata aaagtgttaa taagattaac aaaaatttac tcgttaaagc aaaccaatat
     4201 ttcttagata gtctcactta ttttctccgt atgttaaatt ttataacagt aaatttaaaa
     4261 ttatagtata ttgaaataga atatgaacaa aacgattagg gaatttaaag taatttataa
     4321 aaattcttta gaagctgcat tgtactactc caacttcaaa ccactatagt atcaaaaagt
     4381 ataccccacc tttttaaata aactactcac cacccatttc atccaatggt gatatcaaca
     4441 ccattctatt gataaaaaca ataaccaatg ttcccaatat agcatattta agtaatggag
     4501 ataatatgtt agcaaaatca gcacgagtag aataaataaa aataggtatc atatacagat
     4561 atatcagcat cccgtatata tttctttgag cgtttatata aagaaatctc atcaaaaagc
     4621 ctgttagcat aaaaatcatt acaattccaa agtatcctcc attcacatat ccctctccca
     4681 caagagtaaa accatatttg gttgaatgta cgtttggaaa aaaggtgtcc ataaaccaag
     4741 tttgattaga ataccccgta ttataaaaaa ttcttactat gtcattaaaa aaagaacgac
     4801 cttcgaaata attgcccata ttatgtaata tcagaatctg taaattacga ctagctgata
     4861 caaactcacc atctagcaaa tcaaaccaaa tattatttgt atttatagat gaaacttgcc
     4921 cacttaataa agtatattta aaaactgcag ataacggaat cagtagtgcc gcaagcggaa
     4981 ctaacattac aagataaaaa cgttttattt tgtgaaagta aaataatata atcacatcaa
     5041 ggatgaataa agtaaacata taatctcttt cccctgtaac gatagagaag agacagataa
     5101 ctatcgctgt gttagtatta caatttagta gtctccattt tttagtactc aactgtataa
     5161 atagctgata tgtatgaatg agaatcataa aataaaccaa agaaaatact aacattatca
     5221 caatattggc acctgaatat atttcccctt tatttctaaa accacttcct aatagatata
     5281 taattgctac tgttgtgata aacgtattca tattattgag aaataataaa tagttattgt
     5341 tatttaggtt tattttcctt tcgcttaaca caatggcttt agaaggtaga gttaacaaca
     5401 aagttgccaa agccagccat tgcatgaaaa tcaaatcttt tgtataacca tagtttatat
     5461 actccattct atagagtagc gggtaagaaa tagaataaat agtaaagaag ctactatacc
     5521 acacataggg atgaaaaata ttaaatttca caattatcat tgccataaaa cttaaaaaaa
     5581 tcattgaaaa taatggaatt gtaacatcat tattttcact gcataaaatt aaagtccctg
     5641 aaaaaactac acctactaga agtattattt tattttttat atcatttgat tgtagactaa
     5701 acttcattta cttttttcct ttaactaata atttaaacgt aatgcgtatt caaaaatttg
     5761 attggctatg tagtcagttt ttatagcata tttaatatat cgaaacggat tttccatcgc
     5821 attttaatct aaaccatcag aattatttaa ttctcttcta atttgagcaa aatagtcact
     5881 tctgcgttta tttaatacac tcgaaagaaa tttttttgag aattcaaact gttttatcac
     5941 catcttttcc ttatccatac taataaaatc tataatagat cccgcaatcg cttgtgaaga
     6001 ggatggagta aatagacaat gtggccccag caactctgga attcctgctt tattagaccc
     6061 tatacaaggg caagcacggc tcatagcttc aattaccgca cgaggtaacc cttcttgtaa
     6121 acttggttgt atatataaat caactttatc caaatactca taaatttgtg atgtagtcaa
     6181 ttcccctaaa aaatggattc tattcgctac tcccaattcc tctgctttct tttttaagaa
     6241 actttgatca ccatcacctg ctaaataata atccaacaaa ataccttgta tttctaatct
     6301 cttcattgct tccaatacaa atctatggcc cttggctcgt acattcacag atgctgttgt
     6361 cattattgaa attttttgag gattaaattt tttcaactta taaagacggc tcttcaaaga
     6421 tctattctct acagaggtaa tattaacatt tgaagcaacg atattagatt taatattagg
     6481 atatctatct tgtaaatatt tttctgtcac gtatatgcaa taattagcgt tttttacaat
     6541 tgatttagtt ttggcgtata tatatggagc taataatttt ccctttaaac tatgatacca
     6601 gtaagaatcc caagcatccc ccattatttc tgtcagatac ggcttaccta tcttcaatgc
     6661 gtagtctgca gtttttgatc caattataga cggaatacga acaactatta agtcgctatc
     6721 aatcattcct tcaataatct tatttttatt ttgaccaaat agaacctgat gtagaccttc
     6781 tatagggata aatttattaa taaagttcgc tttatgatat ccttcagggt atgattccac
     6841 cttctcataa cgactacata gtacaatctc tccaaatgct ttagcatagc gctcataaat
     6901 aaaataagct ttcggtttta aatatatttc atttttatag attgtacatc taaattcagt
     6961 cgctataaat actttcataa tttcatctcc cttgataaac gtttctgaat aaatatagta
     7021 tcagctggaa tatcctttgt tacaacactt cctgctgcaa ccacactatt ctcaccaata
     7081 ctcactccct tcaagacaat gctgttagct ccaatccaaa cattttctcc aatcataact
     7141 ggggccgtct taaatttttt tgctttcaat ccacctggaa cactaacatc atagtcatga
     7201 tcatatataa gtactccagg accacatttt actccagatt taatatctat gtatttacga
     7261 caagctatca tacaattatt actcaaaaat acatcatcag aaatcttgag ttttgctcct
     7321 tttctaactt tcaatactcc cccggcgttt actctaatct tttttcctaa gattaattta
     7381 gcattagatt cctgttcgac agttacattc tttccaaatt ttaaaaaata atgaaaagta
     7441 agatccttgt ttcgacacac ttttaataat atcaagcaaa tatttgcacg aagtaaacca
     7501 acaatatttt ttataatcct attcatctaa agctcctttt attttatcta aataagcatc
     7561 tataataatt tgacgagaaa aatattgctc tatatacatt ctcccttgaa gtcccatctc
     7621 ttttcgtttt tcattttcta gacctaaaaa aacttccaat atagagacta gttcctcaac
     7681 atttccccct tgaaatatat agcctgtctc tctatcttta acaatttctt tgcaacctgg
     7741 attatctgtc gtaattaaaa cacgtcctga actagcgttt tctagtaata cattgctcat
     7801 tccttcacca tacacactgg gatggataat tgcatgggaa cgggtaatat gaggtatcac
     7861 atctttttgt tgtcccaaat aataaacgat tccttttttt tctaagtcac aaattttaag
     7921 ttcataatta ctctctgtcg gttctataaa gccaataata ttaaactctg ttttgggata
     7981 tcgactctta ataatttggg cagcagccag ataagtatct ataccttttt cttttaatat
     8041 cctaccaata aaattaaaaa cgattgtttc tccttgaatt ccatttccac catttggata
     8101 ctgttgcaca ggatactttt caatgttcac tcctgaccca ggtatcagct tagagtcacc
     8161 caaaatcaag ccaagagttt ttaacatttt catattatat tcattttgaa aaaaaacaca
     8221 atttgatttc ctaaaagaaa ttctaaacag taataacacc aggcttctta cacaagaacc
     8281 cattgttaag acactaccta aacctgttac gttatttata tattttattc ctaaaattgt
     8341 tgcagctagg ctagcatata catttggttt cacggtatat gtcaagacta catccggtct
     8401 atattttctc aataatctta tataactaag aaatagacga atatctttta aagggtttat
     8461 tcctcttcta tcaatagtaa tatcttcata ctcaaattga atagacttca tcaactctat
     8521 cttatctcca taaggacatg acactagcac ttcataccca tactcaacta gtgactctat
     8581 aacttctttt cgaaaacaat agatatcatc gtcatgatta gttattaaca taattttttt
     8641 cttttgtaaa ttcatcaaaa taatcttcct aaaatataat taaccgctac tccattatcc
     8701 tttacaacta tcattttaaa aatagtaatt ttctataagt aattgtttcc aaattgtgac
     8761 actttaaaat tctatacaca tatagaactt acaaactatt tacgaccgta aactccatac
     8821 ttatcaaccg agatatccaa tttatttaaa acaactccca ggaacagttc ccctgtttgt
     8881 tctaattgtt gtttcgcttt ttggacatca cgtttattcg cctcacctgt tgctgttatc
     8941 aagatggacg catcacactt ttgagtgata attgccgcat caataacaat tccaataggt
     9001 ggtgtatcaa caatgatata atcaaaatat ttacgcaatg tttcaatcat atcattaaaa
     9061 tttttacttt gtaacaaggc tgtagggttt ggtgatacag atcccgattg aactacaaat
     9121 aaattttcaa tatttgtatc acataaaccg tgagataaat cagctgtccc agataaaaat
     9181 tctgttagcc ctgtaatttt ttcacgagat ttaaaaaatc ctgacataac tgaatttcga
     9241 atatcgccat cgaacaaaag agttttatag cctgcacgcg caaatgacat tgctatattt
     9301 acggaagtag ttgtttttcc ttcccccgga ttaacagaag taacggaaat tacttttagt
     9361 ttatctccgc tcaactgtat atttgtacac aaggtattgt aatattcttc tgccttctta
     9421 atgaactcca gttttttttg tgctatttct aatgtcggca tctctctctc ctatttcaac
     9481 ttacccaagt ttggtacaac tcccaaaagt gtcatctgca gtgcattttc gatatcttcc
     9541 ggacgtttca cacgagtgtc caaaagttca agaagaagaa ctataacact agttccaatc
     9601 acccctgcca aaaaaccaat tagtgtattg cgtttaatat ttggcgaaga cggtgatatc
     9661 gccggtcttg cctcctccag tgttgtcaca tcagaaacac gagtaatact gataattttt
     9721 tgagcagcta cttctcttaa agagttagcg atacggcttg cctcttcagg aactcgatca
     9781 ctaactgaaa cagagacaat acgggtatca actggtactg ttactttaat tttattagcc
     9841 aaaccttttg gcatcaaatc tagtttcaaa tcagaaataa cttcctccaa aacatcctgc
     9901 gataggacaa tttcacgata gtctttaacc aagtatgctc ctgcctgcaa gtcttgattg
     9961 gttaaaccag gcttctctcc ctgattacgg ttaactagat aaatccgagt cgtactagta
    10021 aactcaggtt tgataacaaa agtactgtag gcaaaagcaa ctgaagaagt tataattgcc
    10081 actaataaaa tgaccaactt tcttttccat aaagctctga atagttgcaa tacatcgatt
    10141 tccaaagtgt tttgttcctt catattttct cctaaattaa ttgatccatt ataatttttc
    10201 tgggattatc tacaaaaagt tctttcgctt ttttcgctcc atatttctta gcaatgatat
    10261 catatgcctg ttgcatatat ggaggtctac tgtctaaatt gtgcatgtca cttgcaacta
    10321 catgaactaa atcacgttcc aaaaaatacc gagctctctt tttcatgaat ttatattttt
    10381 caccaaagaa cttaggtttt gaaacatgat aactatttat ctgagtatag caccccatat
    10441 caatcagttc acgaacacgt ttttcgttat tctctaaagc atcataacgt tcaatatgag
    10501 caattactgg cgtgattccc aacatcaaaa tattgctcaa tcccgtatga atctgacgat
    10561 aggaagtatg catgctaaac tcaatcaagg cataacgact atcattaagg gtaggaattt
    10621 cttttttttc tagcttttct agagcatcca gagtatagta tatctctgcg ccataagcaa
    10681 tgactaaatc atctgctact tcttttgcaa tttcccgaac ctgaagaaag ttttctgcta
    10741 tcttctcttc cggagtttca aacatgccct tgcgacggtg agaggtagag acaatggttc
    10801 tcaccccctg cctgtaggat tctgccaaga gagccttgct ttcctctctt gacttgggac
    10861 catcatctac atcaaagacg atgtgcgaat ggatgtctat cattttatct accctccatc
    10921 acatcctgta tagctgcttt aactacagtt aaactactat catctatttc catcacatag
    10981 aggttactgt ctggcattgc ataagaagga agatccatcc gacctgtccc ttttaaatct
    11041 tgagaattta ctttataatt ccctccactt tccaactgag tattcactaa atctatcata
    11101 gtctcaatcg gtatatttgt ttgaagagaa tcctgcaatc cttgaagaat actactatag
    11161 tttttcaaaa cctctgtaga agttaacttc tgaataattg ctacaatgac cttttgttgg
    11221 ttgcgaccac ggtcacggtc tccatcggtt agtgagtagc gttcacgtac aaaacctaaa
    11281 gcttgctcag agtctagatg gacattccct actgggaaat ggaacttccc atgtagagct
    11341 gaaaactctt gatcattatg aacatctacc cctcccaata agtcaatcat tttcaagaaa
    11401 gaagtgaagt tcaatcgcac atagtaattg atatccactc catagagatt ttctaaggtg
    11461 tgaatggacg aatcaactcc ataaatgccc gcatgggtta atttatcttt ttgattattt
    11521 ccactatctg cgattggtac ataggcatca cgtggcgttg tggtcaagag gattttcttg
    11581 gtatctcgat tgacagtcat taggatattg acatctgatc gcgacaccga actaatagga
    11641 ccataggtgt caattccact aacatagata ttgaaagact gattcttaga cgtcttagga
    11701 gcctctactt ttttagtgaa tcccttggta taaatctttt ttatcttcga tgcgtagtct
    11761 ggatactctg actcgatgat attttcaaag acactattta ggacaatggc cttagtctcc
    11821 cctgcaatca aactcttgta agctgccaag taagacgaac tctggttgac cgtcaaatcg
    11881 gtattctgac ttgacttgat atcagctagt agtttttgaa tattttcatt atcagtccca
    11941 gtcggtgctg tcacactcgt cagttgcgta acattttcga tcttactatc tgctaaaaca
    12001 gcgacactga ttgaatattc tgagtaatta gaagtcgcat ttaaacgatt ggtcagtcca
    12061 acaaactgct gtactgcaaa gagcgacact gagctgacaa ggatagagaa cagcaacaga
    12121 aaaatagtaa acttttcagc ttttttatag ataatcaaga gtagccctac caaggcaact
    12181 agtaggacta acgcagttac cactaggtta agatatctaa aagcaaggat attgtactta
    12241 aagattaaga acaataaaaa acaaattaac aataaataaa tagtcagcaa aacgatatta
    12301 acacttcgct tcactttctg tgaacgtgat tttttaaaac gtctactcat gattaacacc
    12361 tataccttga acatcataca attatatcac ttttttacgg taatgtctac acctttattt
    12421 tcactatctg catctttaag tatcttagta gacttcccgc gaaccaaaaa tatagtaaaa
    12481 tgaaataaga ataggacaaa tcaatcagga cagtcaaatc gatttctaac aatgttttag
    12541 aatcagatgt gtactattct agtttcaata taa
//
LOCUS       DAVAZV010000058        12109 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVAZV010000058 DAVAZV010000000
VERSION     DAVAZV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12109
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.058"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..150
                     /locus_tag="VQT46_001750"
     CDS             <1..150
                     /locus_tag="VQT46_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371725.1"
                     /translation="LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLIAGIIN
                     HELGF"
     gene            342..2633
                     /gene="pcrA"
                     /locus_tag="VQT46_001751"
     CDS             342..2633
                     /gene="pcrA"
                     /locus_tag="VQT46_001751"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET2371726.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            2676..3356
                     /gene="radC"
                     /locus_tag="VQT46_001752"
     CDS             2676..3356
                     /gene="radC"
                     /locus_tag="VQT46_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET2371727.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(3353..4042)
                     /locus_tag="VQT46_001753"
     CDS             complement(3353..4042)
                     /locus_tag="VQT46_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET2371728.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYNLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(4060..4701)
                     /locus_tag="VQT46_001754"
     CDS             complement(4060..4701)
                     /locus_tag="VQT46_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET2371729.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(4784..4999)
                     /locus_tag="VQT46_001755"
     CDS             complement(4784..4999)
                     /locus_tag="VQT46_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2371730.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(5007..5354)
                     /locus_tag="VQT46_001756"
     CDS             complement(5007..5354)
                     /locus_tag="VQT46_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET2371731.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFSLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(5359..6474)
                     /locus_tag="VQT46_001757"
     CDS             complement(5359..6474)
                     /locus_tag="VQT46_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET2371732.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(6484..7443)
                     /locus_tag="VQT46_001758"
     CDS             complement(6484..7443)
                     /locus_tag="VQT46_001758"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2371733.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(7556..8125)
                     /locus_tag="VQT46_001759"
     CDS             complement(7556..8125)
                     /locus_tag="VQT46_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET2371734.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            8253..8924
                     /locus_tag="VQT46_001760"
     CDS             8253..8924
                     /locus_tag="VQT46_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET2371735.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            8908..9726
                     /locus_tag="VQT46_001761"
     CDS             8908..9726
                     /locus_tag="VQT46_001761"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET2371736.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            9723..10619
                     /locus_tag="VQT46_001762"
     CDS             9723..10619
                     /locus_tag="VQT46_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2371737.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            10663..11637
                     /gene="pta"
                     /locus_tag="VQT46_001763"
     CDS             10663..11637
                     /gene="pta"
                     /locus_tag="VQT46_001763"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET2371738.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(11953..>12109)
                     /locus_tag="VQT46_001764"
     CDS             complement(11953..>12109)
                     /locus_tag="VQT46_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371739.1"
                     /translation="YSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFTALNIKKERT
                     KFVLSRA"
BASE COUNT         3528 a         2310 c         2606 g         3665 t
ORIGIN      
        1 ctatccaagg agagaagcaa ggttgagaac atctttgcca aagtaaaaac gtttaaaatg
       61 ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa tttgattgct
      121 ggcattatca atcatgaact aggattctag ttttgcagga agtctattga ggtattgagc
      181 tagtttatga aaaaattggg tgaaaaagtc gagtgtttta gaaacccaca gtgtagtatt
      241 ctagtttcaa tccactatat tttgctactc cccgtaaagt ttctattttc cctgatttct
      301 gatataatag aaatattgac ttcaagagta aggaagagaa gatgaacgca ttattaaatg
      361 gaatgaatga ccgtcaggct gaggcggtgc aaacgacaga aggtcccttg ctaatcatgg
      421 caggagctgg ttctggaaag actcgtgttt taacccaccg tatcgcttat ttgattgatg
      481 aaaagctggt caatccttgg aatatcttgg ccattacctt taccaacaag gctgcgcgtg
      541 agatgaaaga gcgtgcttat agcctcaatc cagctactca ggactgtctg attgcgacct
      601 tccactccat gtgtgtgcgt attttgcgtc gcgatgcgga ccatattggc tacaatcgta
      661 attttacaat tgtggatcct ggtgaacagc gaacgctcat gaaacgtatt ctcaaacagt
      721 tgaacttgga tcctaaaaaa tggaatgaac gaactatttt ggggaccatt tccaatgcta
      781 agaatgattt gattgatgat gttgcttatg ctgctcaagc tggcgatatg tatacgcaaa
      841 ttgtggccca gtgttataca acctatcaaa aagaacttcg tcagtctgaa tccgttgact
      901 ttgatgattt gattatgctg accttgcgtc tctttgatca aaatcctgat gttttgacct
      961 actaccagca aaaattccaa tacatccacg ttgatgagta ccaagatacc aaccacgctc
     1021 agtaccaatt ggtcaaactc ttggcttccc gttttaaaaa tatctgtgtg gttggggatg
     1081 cggaccagtc tatctacggt tggcgtggtg ctgatatgca gaatatcttg gactttgaaa
     1141 aggattaccc caaagctaag gttgttttgt tggaggaaaa ttaccgctca accaaaacca
     1201 ttctccaagc ggccaacgag gttattaaaa ataataaaaa tcgccgtcct aaaaatctct
     1261 ggactcaaaa cgctgatggg gagcaaatcg tttactatcg tgctgatgat gagctggatg
     1321 aggctgtatt tgtagccaga accatcgatg aacttagtcg cagtcaaaac ttccttcata
     1381 aggattttgc agttctctat cggactaatg cccagtcccg tacaattgag gaagccctgc
     1441 tcaagtctaa cattccttat accatggttg gcggaaccaa attctacagc cgtaaggaaa
     1501 ttcgcgatat tattgcttat ctcaacctta ttgctaattt gagtgacaac attagttttg
     1561 agcgtattat caacgagcct aaacgtggaa ttggtctagg tacagttgag aaaatccgtg
     1621 attttgcaaa tttgcaaaat atgtctatgc tggatgcttc tgctaatatt atgttgtctg
     1681 gtatcaaggg taaggcagcc caatctatct gggattttgc caatatgatg cttgatttgc
     1741 gggagcagct agaccactta agcattacag agttggttga gtccgtccta gaaaaaacag
     1801 gttatgtcga tattcttaac gcccaagcga ctctagaaag caaggcaagg gttgaaaata
     1861 tcgaagagtt tctttctgtt acgaagaact ttgatgacac cactgatgtg acagaagagg
     1921 aaactggtct ggacaaactg agtcgtttct taaatgactt ggctttgatt gccgacacag
     1981 attcaggtag tcaggagaca tcagaagtga ccttgatgac cctgcatgct gccaaaggtc
     2041 tcgaatttcc agttgtcttt ttgattggga tggaagaaaa tgtctttcca cttagtcgtg
     2101 cgactgaaga tccagatgaa ttagaagaag agcgccgtct agcctatgta ggtatcacgc
     2161 gtgcagagaa aattctctat ctgaccaatg ccaactcacg cttgcttttt ggtcgtacca
     2221 attataaccg tccgactcgt tttattaacg aaatcagttc agacttgctt gagtatcaag
     2281 gtctggctcg tcctgcaaat acaagcttta aggcatcata tagcagtggt agtatttcct
     2341 ttggtcaagg tatgagtttg gctcaggctc ttcaagaccg taaacgcggt gctgccccaa
     2401 aatcgatcca gtcaagcggt cttccatttg gtcaatttac agctggcgca aaatcagcat
     2461 ctagcgaggc aaattggtcc attggtgaca ttgctctcca caagaaatgg ggagagggaa
     2521 ctgttctgga agtttcaggt agcggtgcta ggcaggaatt gaaaatcaat ttcccagaag
     2581 taggtttgaa aaaactttta gccagtgtgg ctccaattga gaaaaaaatc taattttcca
     2641 tccttctcac gaataataaa gtgaggagga tttttatgta cagtatttca ttccaagaag
     2701 attcactatt accaagagaa aggctggcca aggaaggagt tgaagcgctt agtaaccaag
     2761 agttgctagc tattttactc aggacaggaa cacgtcaagc tagcgttttt gaaattgccc
     2821 aaaaagtctt gaacaatctt tcaagcctaa cggatttgaa aaaaatgacc ctgcaggaat
     2881 tgcagagttt gtctggtatt gggcgtgtta aggccataga attacaagct atgattgaac
     2941 tggggcatcg tattcacaaa cacgagactc ttgaaatgga aagtattctc agcagtcaaa
     3001 agttggccaa gaagatgcag caggaattag gggataaaaa acaagagcac ctggtggcac
     3061 tctatctcaa tactcaaaat caaatcatcc atcagcagac catttttatc ggttctgtaa
     3121 ctcgtagtat cgctgaaccg cgagagattc ttcactatgc aatcaagcat atggcgactt
     3181 ctcttatctt ggtccacaat catccttcag gagcggtagc gcctagccaa aatgatgatc
     3241 atgtcactaa acttgttaaa gaagcctgcg aattgatggg gattgttctc ttggaccatt
     3301 tgattgtctc tcattctaat tactttagtt atcgtgaaaa gacagattta atctaaagtt
     3361 cattaacgac atagtcaaag agttttttat ctttgggacg attttcaaaa agaagttctg
     3421 gatgccattg gacaccgaga aaggcgacat catccgtact catgacagcc tcaatgatac
     3481 catctttagg atcatgagcc acaactttta aatttggtgc taagtccttg atgctctggt
     3541 ggtggaagga gttgatatga gagatttctc catagatttc ttggagaacg gtatctggtt
     3601 ctgttaccaa gcgttgagtt gtgtactcaa cagaagaatc ctgccaatgg tcttcgatat
     3661 cttggtacaa agttccaccc atggcaacgt taaagagttg ggtaccacgg cagacagaga
     3721 aaatgggctt tttctgttta atagcttcct tgatgagggc cagttcgaag atatctcttt
     3781 gaaggttata gtcatcgcta tcaatggttt tgggttcgcc ataaaatttt ggatcgacat
     3841 tttgcccacc tgtcaagatg agcttgtcaa tcaaactgat atagtggcag gccatttctt
     3901 gatcaccaat cggtaggatg atgggaatcc ctccagcatc tttaacgcct tcaacaaagc
     3961 cttttgctgc gtagctcatc atgatgtcat catctggatg agctttttcg tttcctgtaa
     4021 tcccaataac tggttttttc ataaaatgat tttcgctttc taatcctctt ttcgcatgaa
     4081 gtagaggagg gtttggagtt cacttgtcaa atcgacatac tgaacgacca cgtcttttgg
     4141 taaatgcaga tggactggtg aaaaactgag aattcctttc acaccagcat caaccaagag
     4201 attagcaacc tcttgtgact tgacgctggg aacagttagg atagcagtct tcacatcagc
     4261 atccttgatt ttatccttga tctgagaaat cccgtaaatg ggaatcccgt caggagtttg
     4321 ggtaccgact tcaggatggt cgtctaggtc aaaggccatg ataatcttca tcttgttacg
     4381 ttcgtggaag cggtagtgga gaagggcatg gcccatattt ccaataccaa ccagcatgac
     4441 attggtaata gagttgtcat tgagcaaatc ggcaaaaaat gtcattagtt ttttgacatc
     4501 atagccaaaa ccacgacgac caagttcacc aaaataggaa aaatcacgac gtacggtcgc
     4561 tgaatcaata ccgatagcct ctgcaatttg cttagagttg gcacgttcaa tcttttctgc
     4621 atgaaatctc ttaaaaattc gatagtagag agagagtctt tttgctgtag cttttggaat
     4681 agcaaactgt ttatctttca caaaatcaca acctttctat tcttctattt tatagaaaca
     4741 ttgtgaaaaa atcaacaaaa ataagaaaaa actaagaaaa atcttagttt tgatgtaaaa
     4801 aatctgcatg agatagaaaa cggtagaggt ctccgaccag accctgataa actttttggc
     4861 ccctaaaagt cagagaagtc acataaagtg tatctggtaa ggttacacat cctgacaaag
     4921 tcaacatgag agcctcatga tcctcatact tgagagtacg ctctacatga tagcagtcct
     4981 tataggtcag ttcaaacatt ttggctctat ctttccgatt ttgtaaagac accacgttct
     5041 accaagctat ccatgaggaa gtagaatttt tcctgatgaa tatggtggtc ttctgatttg
     5101 aaaatatcaa ctagacgaag gctaaacttg tcagtgatat tgattttagc ccctgtaagt
     5161 tccttgttaa tgatgatttt gagttggaag ccttcaccgc tgtttggcac tttttccaaa
     5221 aggcgagtca gttcatagtt accaacctta gtttcaaaaa aggtgttatc tttgagggtg
     5281 aattttttaa cagaagggct aagagtgtaa tcgtaacgac aattttttaa ctgaatgatt
     5341 ttttcaaatg ccatatggct aacctccgat aatttctttt aaggtttttg cgagggtttg
     5401 taggtcttca acggtatttt gtggcgacaa actgatgcga agggattcct tcaagcgttc
     5461 tgaatttgcg ccatacatgg cttcaagaac atggctggat tggacaacgc ctgcagtaca
     5521 ggctgagcca gtagagattg aaattccagc taaatctagc cgaaggagta agaggtcatt
     5581 tttctgacca ggaaatccaa tattgagaac ataagggaga tgatgttttc ctctattcaa
     5641 gtaatactga atgccctcca gctctgccag aaaggcggtt tctagatttt gtacatgttg
     5701 aaaatgttct tcttgttttt ctaggtcttc ttttagggct gcaaccatgc ctacgatagc
     5761 aggcagattt tcagttcctg cacgtttttt ctgttcctgg tctccgccat gtagatagga
     5821 atcaaagtcc atgctagatg cgtagagaaa accgattccc ttaggaccat ggaatttgtg
     5881 ggcagaagca gtgagaaaat caatgcccaa ttcttctgaa tgaattggga ttttaccaat
     5941 agcctgaact gcatcaacat gataggcagc agggtgttgc ttgagtattt ggccaatttc
     6001 agcgatgggc agtaggtttc ctgtctcatt attggcaaac atggtagaaa ccaaaatcgt
     6061 atcgtcacgt aaagcctttt gaatttgctg ggctgtgatt tcttgatttt ctggctggat
     6121 aatggttgct tcaaacccaa agtgttgaac caagtaatca attgtttcaa ggacagcatg
     6181 gtgctcgatg gcagttgtga tgatatgttt tccttgttct tggtgacgaa gacagtagcc
     6241 aatgatggta gtattattgc cttcagtccc accagaagtg aaaaagatat gttgaggttt
     6301 tgtccttagt aactgggcta gttcctgacg ggcttctcgc aagagtttgc cagcttgacg
     6361 accatgacca tgaatactag aaggatttcc gtgggtttct tgcataacct tggtcatagc
     6421 tgaaatagca actgctgaca taggagtcgt tgcagcattg tccaaataaa tcaaagaatc
     6481 accttatttc tttttattgt aggcaaagag tgggctgact ggttttcttt cgtgaatacg
     6541 gacgatagca tcaccaatta actcactagc agtgatgtag catacatttt taggagtttt
     6601 ttcttttgtt gctactgaat cagtcacaag aatttcttta atattagtat tgtcaagaag
     6661 ctcagcagct ccctcgacga agagaccgtg gctagaaaca gcataaattt ctgtagctcc
     6721 ttcacgttca acgattttag aagcttcaga gaaggtacgt cctgtattta aaatatcatc
     6781 aatcaagata gctttcttac cttcaacatc accaataata taaccttcgt tacgagttgc
     6841 atcgtcttga gggtagtcga taatggcgat aggagcatca agatattcag ccaggctacg
     6901 cgcacgtttg acacctgaat ttttagggct aacgacaaca acatctgaac caagcaatcc
     6961 tttatcgcag taatgttttg cgaatagggg aacagtgaaa agattatcca ctggaatatc
     7021 aaagaaacct tgaacctgaa cggcatgcaa atcaagagtc aggatacgat caactccagc
     7081 cttaaccagc atattggcaa ctagttttgc tgtaagtggc tcacgaggac aagcaatgcg
     7141 gtcttgacgt gcatagccaa aatatggaag gacaacgttg atactgtggg cacttgcacg
     7201 cacacaagca tcgaccatga ttaacaattc cattaggtgg ttgttgacag ggaaacttgt
     7261 tgattggatg atgtaaacat cataaccacg gacactttct tcgatattta cttggatttc
     7321 tccgtctgaa aattgacgtg atgatagttt tccaagtggg acaccaacag cttgggcaat
     7381 tttttgtgca atctcttggt tagagttgag tgcgaaaagt ttcatgtttt ttctatctga
     7441 cattatagac cgtcctctgt aaactttata aatcctagtt atatttacct tacatatatg
     7501 aactgggatt tgtgtatttt tatcttttct attttaccaa aaaatggaga ttatttcagc
     7561 tatttttcat acttttgaca aatcgaacca attttgaagg agctttttgg taggaaatct
     7621 gatttttctc taaaaattgt cggaaatcct gtttgccttg ctcatgattt tccacttcaa
     7681 gctccaattc gtaatctgtt atatcaaagt atcggctctg atccagtgcc atgagaccaa
     7741 tagctgtttt catttcatag cgaagcgttg ttagacaacc aagaacctgc cagttcttac
     7801 tttggatacc atgtttcgcc aattcatcca gtactagtcc ttgaggaagt tcttccttac
     7861 tcagatagtc ctcagcatct tttagttgca atttttggtt gtattccatg tttccaacac
     7921 tctgcgggac tttgagtgtc aactcagccc agtcttcaaa ggttcgaatg cgcatagcga
     7981 ctttcttttc tcgcagttca aaatcaggcg tgtcgatgta gtaatttgtt tgaagaacag
     8041 gagtgacacc tgtgaactgg tcttttagac gattgtattc atcttttttc aatagtgttt
     8101 tcaattcaat ttctaaatgt ttcatttttc ttaccttttt ttatcgttga aagcggattt
     8161 atggtataat aagcattgta tttattgtat atgaatctgg agaaaaaatc aaagatattt
     8221 ttgacggata atatgagaac aagggagaat atatgacctt agaatgggaa gaatttctag
     8281 atccttacat tcaagctgtt ggtgagttaa agattaaact tcgtggtatt cgtaagcaat
     8341 atcgtaagca aaataagcat tctccaattg agtttgtgac cggtcgagtc aagccaattg
     8401 agagcatcaa agaaaaaatg gctcgtcgtg gcattactta tgcgaccttg gaacacgatt
     8461 tgcaggatat tgctggctta cgtgtgatgg ttcagtttgt agatgacgtc aaggaagtag
     8521 tggatatttt gcacaagcgt caggatatgc gaatcataca ggagcgagat tacattactc
     8581 atagaaaagc atcaggctat cgttcctatc atgtggtagt agaatatacg gttgatacca
     8641 tcaatggagc taagactatt ttggcagaaa ttcaaattcg tactttggcc atgaatttct
     8701 gggcaacgat agaacattct ctcaactaca agtaccaagg ggatttccca gatgagatta
     8761 agaagcgact ggaaattaca gctagaatcg cccatcagtt ggatgaagaa atgggtgaaa
     8821 ttcgtgatga tatccaagaa gcccaggcac tttttgatcc tttgagtaga aaattaaatg
     8881 acggtgtagg aaacagtgac gatacagatg aagaatacag gtaaacgaat tgatctgata
     8941 gccaatagaa aaccgcagag tcaaagggtt ttgtatgaat tgcgagatcg tttgaagaga
     9001 aatcagttta tactcaatga taccaatccg gatattgtca tttccattgg cggggatggt
     9061 atgctcttgt cggcctttca taagtacgaa aatcagcttg acaaggtccg ctttatcggt
     9121 cttcatactg gacatttggg cttctataca gattatcgtg attttgagtt ggacaagcta
     9181 gtgactaatt tgcagctaga tactggggca agggtttctt accctgttct gaatgtgaag
     9241 gtctttcttg aaaatggtga agttaagatt ttcagagcac tcaacgaagc cagcatccgc
     9301 aggtctgatc gaaccatggt ggcagatatt gtaataaatg gtgttccctt tgaacgtttt
     9361 cgtggagacg ggctaacagt ttcgacaccg actggtagta ctgcctataa caagtctctt
     9421 ggcggtgctg ttttacaccc taccattgaa gctttgcaat taacggaaat tgccagcctt
     9481 aataatcgtg tttatcgaac actgggctct tccattattg tgcctaagaa ggataagatt
     9541 gaacttattc caacaagaaa cgattatcat actatttcgg ttgacaatag cgtttattct
     9601 ttccgtaata ttgagcgtat tgagtatcaa atcgaccatc ataagattca ctttgtcgcg
     9661 actcctagcc ataccagttt ctggaaccgt gttaaggatg cctttatcgg tgaggtggat
     9721 gaatgaggtt tgaatttatc gcagatgaac atgtcaaggt taagaccttt ttaaaaaagc
     9781 acgaggtttc taagggattg ctggctaaga ttaagtttcg aggtggagct attctggtca
     9841 ataatcaacc gcaaaatgca acgtatctat tggacgttgg agactacgtt accattgaca
     9901 ttcccgctga ggaaggcttt gaaaccttgg aggctattga gcatccatta gatattctct
     9961 atgaggatga ccactttcta gtcttgaata aaccctatgg agtggcttct attcctagtg
    10021 tcaatcactc taacaccatt gccaatttta tcaagggtta ctatgtcaag caaaattatg
    10081 aaaatcagca ggttcacatt gttaccagac tagataggga cacttctggc ttgatgctct
    10141 ttgccaagca cggttatgcc catgcacgat tagacaagca gttgcagaag aaatctatcg
    10201 agaaacgcta ctttgctttg gttaagggag atggacattt ggagccagaa ggggaaatta
    10261 ttgctccgat tgcgcgtgat gaagattcca ttattaccag acgagtggct aaaggcggaa
    10321 agtatgccca tacttcatac aagattgtag cttcttatgg aaatattcac ttggtctata
    10381 ttcacctgca cactggtcga acccatcaaa tccgagtcca tttttctcat atcggttttc
    10441 ctttgctggg agatgatttg tatggtggta gtctggaaga tggtattcaa cgtcaggctc
    10501 tgcattgcca ttacctatcc ttttatcatc catttttaga gcaagacttg cagttagaaa
    10561 gtcccttgcc ggatgatttc agtaacctta ttacccagtt atcaactaat actctataaa
    10621 aactgtctca gagtataatt attatcttaa aggagaaaac tcatggaagt ttttgaaagt
    10681 ctcaaagcca accttgttgg taaaaatgct cgtatcgttc tccctgaagg ggaagagcct
    10741 cgtattcttc aagcaacaaa acgcttagta aaagaaacag aagtgattcc tgttttgctt
    10801 ggaaatcctg aaaaaattaa aatttatctt gaaattgaag gaatcatgga tggttatgag
    10861 gtcatcgacc ctcaacatta tcctcaattt gaagaaatgg tttctgcctt ggtggagcgt
    10921 cgcaagggca aaatgactga agaagatgta cgcaaggttt tggttgaaga tgtcaactac
    10981 tttggtgtga tgttggttta cttgggcttg gttgatggaa tggtgtcagg agcgattcac
    11041 tcaacagctt caacagttcg tccagctcta caaatcatca aaactcgtcc aaatgtaact
    11101 cgtacttcag gagccttcct catggttcgt ggtacggaac gttacctatt tggagactgt
    11161 gccattaaca tcaatccaga tgcagaagcc ttggctgaaa ttgccatcaa ctcagcaatc
    11221 acagctaaga tgtttggcat cgaacctaaa attgccatgt tgagctattc tactaaaggt
    11281 tcagggtttg gtgaaagcgt tgataaggtc gttgaagcaa ctaaaattgc tcacgacttg
    11341 cgtcctgacc ttgaaatcga tggtgagttg caatttgatg cagcctttgt tcctgaaact
    11401 gcagctctga aagctcctgg aagtacggta gctggtcaag caaatgtctt catcttccca
    11461 ggtatcgagg ccggaaatat cggttacaag atggctgaac gcctgggtgg ctttgcggct
    11521 gtaggacctg ttttgcaagg tttaaacaag ccagttaatg atctttctcg tggatgtaat
    11581 gcagatgatg tttacaagtt gaccctcatc acagcagctc aagcagttca tcaatagtga
    11641 aaactataaa gcgatatact atgctatact gtagttatga aactatgtac gaaaagcact
    11701 gccattaatt cctgagaact aaattactga ttggtgtcaa aaaggaaaac ttccaagcga
    11761 tgatatcctg tctatacacg acctatagaa atctgtaata tgtatgtccg taaaacgata
    11821 atttcccttt ttgattttaa atgagtatga aaagagaatt ttttcatgag aaaacgcata
    11881 atattaagtg tcttgacacc tgctattatg cgttttctgg ctctttgtca actgtagtgg
    11941 gttgaagaaa agctaagctc gagaaaggac aaattttgtc ctttcttttt tgatattcag
    12001 agcggtaaaa atccgttttt tgaagttttc aaagttccga aaaccaaagg cattgcgctt
    12061 gataagtttg atgagattat tggtcgcttc caatttggcg tttgaatag
//
LOCUS       DAVAZV010000059        11962 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVAZV010000059 DAVAZV010000000
VERSION     DAVAZV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.059"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..316)
                     /locus_tag="VQT46_001765"
     CDS             complement(<1..316)
                     /locus_tag="VQT46_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371740.1"
                     /translation="MILSKVRCYIYNSKIRGKVLYELYEFINENKQLMDAINSIKVDS
                     SNGFSIQILHLGEQQTTVLLTDFFTKTLDLFKEFRVTNKSTLEQVKNQISILNSSGPK
                     MDL"
     gene            complement(329..1348)
                     /locus_tag="VQT46_001766"
     CDS             complement(329..1348)
                     /locus_tag="VQT46_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2371741.1"
                     /translation="MSNTLKQLLLFREEFIKNILNGIDVDETVVIENDFVEELENFLK
                     ENDLLDFSNSIFFQLSGDKVIVNNIYPGYLAYFNRFLTFYPKIFAIKEVGEYIDFLNF
                     EKRIADMFYCWGFNANSRVLTAEKIIEIPNHQINAKYIKKVIKMSELLFGVDSNNRIR
                     LLNNRRELIKTIFQGSVIKSAIPALAATLDTISNSGSFQISLSKQIINNLVLSGKDKV
                     TIPRIELDNVVLSRQKIIVSVSYINDFLDLRFPDKIEYILNFLEGSGFNTKVMVYFGK
                     IVEEDKNYFVNLEKPQYFDFTSILFNKLFFKELNKFDYMVIEELIPNLDEDVMMTEYI
                     KEYTE"
     gene            complement(2071..4176)
                     /locus_tag="VQT46_001767"
     CDS             complement(2071..4176)
                     /locus_tag="VQT46_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET2371742.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQEKVIGQDKAVEVVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVVIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(4785..5765)
                     /locus_tag="VQT46_001768"
     CDS             complement(4785..5765)
                     /locus_tag="VQT46_001768"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET2371743.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNMGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVIFYLFYERGGDMLSVFGYQVHLGIFYIVFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLSFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            complement(5767..8019)
                     /gene="pbpX"
                     /locus_tag="VQT46_001769"
     CDS             complement(5767..8019)
                     /gene="pbpX"
                     /locus_tag="VQT46_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET2371744.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDSFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAVYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGLT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKVEEVPDMYGWTKETAETLAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            complement(8023..8340)
                     /gene="ftsL"
                     /locus_tag="VQT46_001770"
     CDS             complement(8023..8340)
                     /gene="ftsL"
                     /locus_tag="VQT46_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET2371745.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            complement(8352..9302)
                     /gene="rsmH"
                     /locus_tag="VQT46_001771"
     CDS             complement(8352..9302)
                     /gene="rsmH"
                     /locus_tag="VQT46_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET2371746.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            9468..9662
                     /locus_tag="VQT46_001772"
     CDS             9468..9662
                     /locus_tag="VQT46_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371747.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            9678..10220
                     /locus_tag="VQT46_001773"
     CDS             9678..10220
                     /locus_tag="VQT46_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET2371748.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            10231..10473
                     /locus_tag="VQT46_001774"
     CDS             10231..10473
                     /locus_tag="VQT46_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371749.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            10484..10819
                     /locus_tag="VQT46_001775"
     CDS             10484..10819
                     /locus_tag="VQT46_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371750.1"
                     /translation="MKSLARLLNIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(10929..11930)
                     /locus_tag="VQT46_001776"
     CDS             complement(10929..11930)
                     /locus_tag="VQT46_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET2371751.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
BASE COUNT         3543 a         2619 c         2001 g         3799 t
ORIGIN      
        1 ttaaatccat ttttggacca gaagaattta gtatgctaat ttgatttttc acctgctcaa
       61 gagtactctt atttgtaacc ctaaattcct taaacaagtc taaagtttta gtaaaaaaat
      121 ctgttaataa gacagttgtt tgctgttctc ctaaatgtaa tatttgaata ctaaaaccat
      181 tactactgtc aactttaatt gaattaattg cgtccatcaa ttgcttattt tcatttataa
      241 attcatataa ttcatacaga actttacctc taattttaga attatatatg taacaacgta
      301 ctttacttaa aatcataata gattgctcct attcagtata ctcttttata tactctgtca
      361 tcattacatc ttcatcaaga tttggaatga gttcttcaat aaccatgtaa tcaaacttgt
      421 ttaattcttt aaagaataac ttattgaaaa gtatactggt aaaatcaaaa tactgaggtt
      481 tttcaagatt aacaaaatag ttcttatctt cttctacaat tttcccaaag tagaccatta
      541 ctttagtatt gaaaccagat ccttctaaaa aatttaaaat gtattctatt ttatctggaa
      601 atctcaaatc caaaaaatca tttatatacg aaactgatac aataatcttc tgtcttgaaa
      661 gaacaacatt atctaactct atcctaggaa ttgtaacttt atctttacca cttaatacta
      721 aattattaat tatctgcttt gataaagaaa tttgaaatga tccactgtta ctgattgtat
      781 ccaaagtagc agctagagca ggaattgctg acttaattac agaaccttgg aaaatagttt
      841 ttatcaattc ccttctattg ttaagcaacc gaattctgtt attactatca acaccaaaca
      901 agagttcact catttttata acttttttta tgtacttagc attgatttgg tgatttggga
      961 tttcaattat tttttcagct gtcaacactc tagaatttgc attaaatccc caacaataaa
     1021 acatatccgc aattctcttt tcaaaattta aaaagtcaat atattctcca acttctttaa
     1081 tagcgaatat tttcggataa aatgtaagga acctattaaa atatgctaaa tatcctggat
     1141 aaatattatt cactattact ttatctccag ataactgaaa aaatatgcta tttgaaaaat
     1201 ctagcaaatc attctctttt aaaaagttct ccaactcttc tacaaaatca ttttctatta
     1261 ctactgtttc atccacatca atcccattca aaatattttt tatgaactcc tctctaaaaa
     1321 gtagtaattg cttcaatgta tttgacatat attcatctgg ataatatgtt tccaaattaa
     1381 cattagcgag tctaggagct tctttgatga ttatgttaac tatatcctga actatttctt
     1441 ctgatgtccc taccttctgg tgttctctcc tgtgtttatt ataataacat tgtccgaata
     1501 gtagctgaaa aaacaaatta ctatcaaata atctcgttag aattaatagc tttcttattg
     1561 acttattatc aacttttaaa ctttcttttt caatttgcct caactctaca atgtcttgat
     1621 aaataaaatt atgttctata aaaatttact tcaactagct atggtttaat agatttttta
     1681 aaggggataa ttgtctaaaa tttaactttt tacaaatcaa gatgtctcta taaactagca
     1741 acctctctaa taactttacc cctatagcta tagacaatcg agtaggggat aatctctagc
     1801 ccctctcaca ccaccgtacg taccgttcgg catacggcgg ttcaactaac ttttaacgca
     1861 tgtcgttcaa ggtaataatc caaacacgaa accagtccac gtttttcaag gactggtttt
     1921 gatatagcac gtttaagtac cgacttctga gctactatag tatattgaaa ctggaataat
     1981 acacttctac tatacgacat gcctgtcgta cctaaaaagg aaccagtttt tttcagctgg
     2041 ctccttcttt tttatcctca aaattctatc ttaggctttc tcacgaataa ccaaaacgcc
     2101 atcttccata tctgcttcca gatgtttagc atctaaatga tccaagtgga agtctgtcac
     2161 cttatcacga atttcttgtt caaccacgcg acggagagga cgaaccccca tgacttcgtc
     2221 gtaaccttct tctgtgatat aatctttagc cgcttgacta actaccaagt caatgtcttt
     2281 cttagccaag gtttggttaa cttcagccaa catcaaatct acaatcttag aaaggtcttc
     2341 cttagtcaag tgtgagaact cgatgactgc attaaagcgg ttgaggaatt ctggacggaa
     2401 gaagggtttc aaacggtcca tcaattctgg tttatccgca tcttctgtca agttggcttc
     2461 atagccaaat ccagcatttg aggtcgcaat aacgacagta ttcttgaagt ttactgtatt
     2521 tccttgacca tctgtcaaac gaccatcatc tagaacttgg aggagaaggg taataacttg
     2581 aggatcagcc ttttcaattt catccaagag aatgatagag tatggattgc gacgaacacg
     2641 ttctgttaag gtattgctat tgtcatcata acccacatag cctgctgttg taccaattag
     2701 cttagaaaca gctgtgcggt cactgtattc agacatatcc aaacggataa tcgcatcctg
     2761 ggttccaaac atatcgagtg ccaattgctt agcaagctcc gtcttaccaa ccccagtaga
     2821 ccctacaaag aggaagctgc cgattgggcg atttccttca tcaaaaccag cacggttacg
     2881 acggatagca cgagctacaa cttctacggc cttatcttga ccaatcacct tttcttgcaa
     2941 gcgatgagcc atatctttca aacgttcgat atctgaagct cccatttgcg atactgggat
     3001 acctgtcatt cgttccacag attcagccac atcgttgaca cttgcagtca ctttcatatc
     3061 ttctgtgtgg ttttcgattt tcctttccaa ttctgcaatg cgtgttttat agtttagagc
     3121 tgcttcaaaa tcttctgctt caactgcttt ttcttgcttg tctttttccg tttcgatttc
     3181 tcgttcaaca gcatgcacat ctgttactgg atgttgagcc gccaagtgag cagccgttac
     3241 atcgacaagg tcaatagcct tatctggcaa gctacgttga ggaatgtatt gaacagaata
     3301 atccaccgct gctttcaaga cttcgtctgg caagatgaca ttgtggtgtt gttgatagag
     3361 gtcacgaatg ccttgaagaa ttttaaaagt attctctgct gaaggagcat tgaccttcac
     3421 ttcgttgaaa cgacgagcaa gagcagcatt cttcaagatg gtgttacggt attcgtcttg
     3481 agttgttgcc ccaatcactg tcaattctcc acgagagaga gctggcttga gaatatccgc
     3541 aagtccttta gaaccactgt ctccaccagt gctaccagca ccaagaattt ggtgaatttc
     3601 atcaaagaag aggataatat tccctgcttc tttcacttca ttgactaagt tttggacatt
     3661 ttcttcaaag ctaccacggt attgagtacc agcctcaaga cctgagatat caatggaaat
     3721 aatttccttg ttcttgatag cagcaggaac atctccgttc acaatggctt gcgctagacc
     3781 ttcgacaact gctgtcttac caacacctgc atctccgacc aaaacaggat tgttcttggt
     3841 gcggcgtgag aggatttcag atgtttcttg aatttccttg tttcgtccga taacaggatc
     3901 caacttgccc tcacgcgctt ctgctgttaa gtttcgacct agttttgcaa ggacaccgtc
     3961 ttgtttcata cctgatgcct gttgtggcat ttgcacatca gtttctgcat ttcctggtaa
     4021 ttgaccagtc gcacgatagt gagcaaattc ctcaggtgtg acttcgcgtc cattaattaa
     4081 gtaacggcga ttttcagaac tatatcctcg cataccaccc atcaattggt taaataaatc
     4141 atccatgtta ttaaaattat taaagttgtt attcatattc tttacctctt tttgtttact
     4201 tagttatgat tactgatatt gactatcttt gaccattgtt ttaaaaaatt tagactagct
     4261 agatcgctac cctacgtact atttctggtt tttctttttc aagcaggagt agactatctt
     4321 tacctctgaa gattgctaga tgaaacatag actcacctct ttctatttta ctttaaataa
     4381 gtgttctagt aaggctttca tttaccttac gttcataata tactacattg gtcagaaaag
     4441 gtcaagagtt ttgactttaa ctgaccaata tttttttaca ctcttcgaaa acctcttcaa
     4501 accacatcag cttcgccttg tctacaacct caaaacagtg ttttgagctg acttcgtcag
     4561 ttctatcaac catctcaaaa ctgtatagta aaatgaaata agaacaggat aaatcgttca
     4621 ggacagtcaa atcgatttct aaaaatgttt tagaagtaga ggtgtactat tctagtttca
     4681 atctactata ttttgagcag cctaaagtta gctttctagt ttgttctttg attttcattg
     4741 tgtatttaaa cacaaaaaca ccctgaaaca tcagggtgcc attcttacat caaatacaaa
     4801 attgcaaggg tcaggagact tgctagaagc ccaactcccc aaaagaagaa gtcaaccttc
     4861 cactcgctcc aaggatttcc tttaccagac aatcccccaa gctcaaaatg gtgatgtaca
     4921 ggcgtcatac ggaaaatacg tttaccacct gtcagtttga aataactgac ttgcatcata
     4981 acagaagttg tttcaaaaac atatacaatt ccgataatca agagagtcca ttcttggtgg
     5041 agagccatag agatagctgc cagcatccca cctagggcca aacttcccac atcacccata
     5101 aagaccttag caggcttatg gttaaagatg aaaaaactga gcaaaccacc aatcatggca
     5161 agaatcacta gaagaatatc catctgacct tgcacatagg caataactcc ataggcagac
     5221 aaactaatca caacggaaat actagctaaa ccgtcaacac cgtctgtcaa gtttactgcg
     5281 tttgaaaaac cgactagcca gaaaagagcg aagacaatat agaaaatccc tagatgcact
     5341 tgataaccaa agacagaaag catatcgcca ccgcgctcat agaaaagata gaagataact
     5401 ccacctagaa gctgaagagc taatttttgc ttaggattaa gcccctcatt gattttacga
     5461 aagaccttga gaaagtcatc taaaaatccg accaagccat acaagaccaa gatgaacaaa
     5521 atcattccca tattattgct gaattggcta ctaaataggg cgaaaaagaa agcaaccaaa
     5581 acagaagtaa tcaagaaaac caaacctccc attgtaggag tcccagcttt tgcctgatgc
     5641 tgtttgacat cctcatgcat ctgctggcct gtaatttgcg cctttctata aaattggata
     5701 aaggccggaa ttcctactaa agttagtaaa aatgtcacaa ttccagcact gatggaaata
     5761 aacatattag tctcctaaag ttaatgtaat ttttttaatg tccttgatag ctgtgttagc
     5821 acgaacatct tgcttctgca cagtagagcc cgaaccttga aattcaagtt ctatattgag
     5881 ccacttagca agggtctcag cagtctcctt tgtccaacca tacatatctg gaacttcctc
     5941 tactttatca gataagataa ggacttgctg attcggggca agattcttcc cttcttcagc
     6001 agaactgttt ttaatcttcg ttcctgttcc cacaacgatg ggttgtacaa gattgcgacg
     6061 caattcttct gctaaatcac caggtgaaat atccttgaca ctaggcatag gataaggact
     6121 ttgttgactt acttgctcca aagctttagc tgttgtttga agattgagag agtctttcat
     6181 agctgaagcc cgctccaaga taggattggc aaattctccc aactgaatac ctgaataatg
     6241 ttcaggttgt tggaccgtca catacaagat aaaatcagga ttttcagccg gactcatcga
     6301 tacagccgag aaaatatagt cggttaaccc gactagataa ccaccatttt tctcgtcagc
     6361 aatctgagcc gtaccagact tgagggctac attttgccca ggaacagtta cagttggctt
     6421 gcctgtgctg tggttataca tggttccata aaccggatcc gtccctacca aaaccatgtt
     6481 agtccgagtt agactagctg catctttaga aacaggattt cccacaattt ctttttgaga
     6541 tttccgagca gtttgatcat ttggatcata aacggcacta ataaatttag gctccagcat
     6601 gacaccgtca ttagcaatag ctgtaaaggc acgaatcatt tgcgtctggg tcactgaaat
     6661 cccttgtcca aatgagcttt gcgcaatgtt gacaatatta tccgcaggaa gctgaccagc
     6721 atactcatcc gtcaaaccga aacgggtcgg aactccaaac ttaaaacgat taagataatc
     6781 aagccaggta gcatctccca tcttttgctc aaggagggtc atcccaacgt tacttgagtg
     6841 tgcaaaacct tgagaaaaag tcatcattct gccaccagtc aatccttcat taacgtccca
     6901 atctcgaatc gtggcatctg caatttttaa ctcactacta ttaaagactt ctcctcctgg
     6961 aaaggtatta ttatcaatag cagcagccaa catcatcact ttcatagtgg aacctggctc
     7021 atagttactt tggtaaagga tatcacgcca aacaaagtcc tctgtaatgc cttcttttgt
     7081 atctgcatca aaggtcggtc gttgcgttgt tgccagaatt tcccctgttt tagcactgac
     7141 caaagtcgct gtcatgtact ttccttttac cttctcttga aaagaatcca tctgggtttc
     7201 cataaaggac tggagggggc tggaaatggt tgtataaaca tccttaccgt ccatcgttcg
     7261 ttgggaaact tgttctgttc cgggtacaat attacccaga cgatcctttt cataggtaat
     7321 aatgccgtct gtccctgcaa gaatactgtt caaggaactc tccattccag aggttcccag
     7381 caagctcttg cttccatctt cattttcatg gagctgagct aggccgataa aactagaagc
     7441 aaattgtccg tttgggtaac tacgattggg actggttgta aaatcaatcc ccttgacctc
     7501 tgcagcttcc aattcttttt tgatagacat catattggca taggtaatcc catttccctt
     7561 tgctccaaag gaaacttgct tgagattagg ttgcgagagt tgctctctta cataggattc
     7621 ttccatgtcc agatacttat gaaagacctc tgcaaccttg ttaaattgtg ttttttctac
     7681 gtaaagaatc ttacccgttg ctgacttata gttctcatca atgaccgcat agacattata
     7741 ggaggttgca tcctcagcaa tcgggactcc atttcggtca taaatagtcc cacgtttggc
     7801 aggaactgta cgggtggttt gatgaacctt cttagcttcc ttcgctaaat ctgttccaaa
     7861 gcgagtgcct gtcccaataa tgaccgcaaa attgactaaa aaaatggcaa aaacaaagac
     7921 agataataaa ctcagacttt ttccaactct gcgtctgttt tcagccggcg atttccgatt
     7981 tttggtcgca taacggatta ctctttttgt ccacttcata tcttactccg ctattctaat
     8041 attttcattg tttaattgca aatcgtgtga attggcaatt tctttcaaac gttctgcacg
     8101 taatagttca ttgacctctt gcttggcatc gtccaattcg gtcttctttt cctctatctg
     8161 cgcattgatt tttgtcaaat cattctgcac ttgcaagagc ttggtctgca taaaaataat
     8221 actaatggct acaataagag tggttacagc aatggaaaag taaaaagctt tttccacacg
     8281 cgaaaaccgt ttaagttgca tctgtagtat ttgacctgtt ttttccattt tttctgccat
     8341 ctttttccct cttacttgtg aatttttctg gccacgcgca acttggctga gtgcgagcgg
     8401 ttattggctt ctaactcttc cgcacttggc aagattggct tacgggacac caattccatc
     8461 ttgggcttga gatcatctgg gatgaaaggc aagccttttg gaacttcaac tgttgaagct
     8521 tccttgaaca attgcttggt caagcggtct tctaaggaat gaaaggtaat cactgaaatt
     8581 ctaccatcca gagccaacat atccatagcc tgctggatgg actcatctgc cgctcccagt
     8641 tcatcattga cttcaattcg aatagcctgg aaaatctgct tagcaggatg acccttcttc
     8701 ttgagttcct tggcaggttt gaccaacttg ataatctctg ctaactcagt cgttgtctca
     8761 atcggcttca cttcacgcgc ttgctcaatc ttacgcgcaa tctgtttaga gaatttatcc
     8821 tcaccgtatt tgaagaaaat acgaaccaaa tcatgatagt catagtgatt aaccacttca
     8881 taggctgtca gactagcatc ctgattcatc cgcatgtcca gtggcgcatc ctttttataa
     8941 gaaaaaccac gctcacgctg gtccaattga ggactagaca ctcccaagtc ataacaaatt
     9001 ccatcaattt cctgaacacc agcttcgcgc aaacgtgcct gtaaatgacg gaagttatcc
     9061 ttgataaagg tcaccattcc cttctcaatg taaggtgcca agcgtttttg cgcattgtca
     9121 atggcattct gatcctggtc aaaggcatag agatggcctt tttcacttaa tttacttaat
     9181 aaatactcgc tatggcctgc tccacccaaa gtcgcatcaa cgtagatacc gtcaggtttt
     9241 acgtcaagca tatcaatcgt ttcgtggagt aagaccgtta catgatgaaa ttcttttgtc
     9301 atatcttatc tattttacca caaatccgac cagcttgcac ttgtcagaca aataggacaa
     9361 ggagactact atttcttcaa aaaatatgtc aaatatactt gacactttat gtttaaaaga
     9421 ctataatata gtcaaatata tacgacataa atcagaaagg agaccagatg aatcgtgtga
     9481 aagaatttcg caaggaattg ggtatttccc agctcgaact cgccaaggat atcggtgtct
     9541 cgagacagac tatcaatatg attgaaaacg acaagtacaa tccaaccttg gaactctgtc
     9601 tcaatctcgc ccgcagcctc caaactgacc tcaacagtct cttttgggag gaagattttt
     9661 aaaaaaggag caaactcatg aaaaaagaaa ccttcactga aaaactgatc aaacgcacat
     9721 acggtatttc tggtcccctt gacgaataca aacggcgtga ggccgatagt attgggaacc
     9781 aagtctttat cgtcctcttt tatctgatga ttttcggaaa tcttattcca ctccttctag
     9841 cctataaata ccctcaagaa gtggctctaa tctatcctcc tctgatttta gtgattgccc
     9901 tcatcgctgc tggctatgtc acctaccaaa tgaaaaaaac aggcatcaca gtcattgaac
     9961 cagatatgct gaatgagaaa gaaagcaagc aactacacta cccaggtctg aaagcaggtt
    10021 tgttctttgg tctatggatg ttttttataa ctcctcttct cagtatactc atagatgaag
    10081 gtcaggacta ttttcattct cttctcacta taagaaatgg tgtatcaagt attctcggtt
    10141 ctattttctt cggagcgagc atacagttcc tcatctcccg tcgcattgca aaaactaaga
    10201 aaaatcaaga tgaggattag gaggaaactc atgaaaaaag aaaagaaaca gttacgttat
    10261 cctggtctga aagcaggttc gatttatgga acagtgatat tttttataat tccactcatt
    10321 gataccctaa caagtgaaaa tccaaatttt atcagttctc ttctaaatac aaaacatatt
    10381 tttaaaacta tactgggagc tttctttttc ggagtgatga tacatattgt cgactcactt
    10441 cgtattgcaa gagctaaaaa agaccaggat taggaggtgc cttatgaaat cactagctag
    10501 actactgaac attcatgttt ttatcagtat tttccttttc ttcgccctta tttcaggagc
    10561 tgtttctcat acagttttac tactcctact cctctttctt cctgcgctca ataaaggact
    10621 tgagaaaata caatcaaaac ggatacctgt cctcaacgca gccctcttct ttctcctcat
    10681 atcctttcca caacttttaa ccaaccctgt ccaatggaaa ttttcaatat tcctagtcgt
    10741 aaccatcatt tcaagtttgg cctacttcta taacttttat caagtagtta aagaagtaga
    10801 tcaaaaacag ttgatttagg agcttgctcc cataatttct catttcataa gcaaataatc
    10861 ccacctagct tgttctaggt gggattattt tatttcttaa cagagattgc aagtcatttt
    10921 ccttcatttt agaaagtcga ctctttccaa ttcacactac aatccaagac ttgttgcctt
    10981 tcttcttgat tacggccttc aatctgatca atcaaaatct ttgtagcctg ttgtccttcc
    11041 tcaaaggagg gctgaaccag cgtcgaaaca cttggagaag aaaagcaagt ccactccgta
    11101 ttgtcaaaac caatcaaccc aacttgtggc aagttataat tcaactcttt gataacggta
    11161 aagactagag gtagggccca acagttaggg ataaatacca gagttttttc atcgggatcg
    11221 atttcttttt gtaaaaattc cttaatttgt tccaaattcg tatgcttatc ttcaatggtt
    11281 agactggcgt gacgcatatt agcatctgtt aaagcatcca caaaaccact tgcccgctca
    11341 atccgagtac tcaaacgact cgtatccgct gtaatcaaga gaaaatgctc ataacctttt
    11401 tcgatacagg actgggtcat gtcataaacg gcatcatagt tattggtttt aacccagcta
    11461 gtccggtgtt catagagctg actatcaaaa aagaccattt tcttcttttt ctcatcgatg
    11521 atacgagaat attttcggaa attagaggtc ggctgaataa taaagccgtc tactcccaag
    11581 agaagcatgc tttcaatata ccggtcctca ctctcttggc tgtaattact atttcctatc
    11641 attacctggt agccattctg gctggcgata tcctcaattc ccttaacaat ttggtttgag
    11701 aaactgttgg taatatcacc gatcaaaaca ccgattaatt ttgttcgttt ggagtttaag
    11761 ctacgcgcaa caatgctcgg tttgtaattt gtttcatgaa taactttttc aatcttttca
    11821 cgtgtctctt gggacatttt ttcatatttc ccgtttaggt aaaatgacac ggttgttttc
    11881 gaggtctgag ccatttccgc aatgtctttt atggtcagtt tcttctccaa tctaaaacac
    11941 ctcctactaa tacttattat aa
//
LOCUS       DAVAZV010000060        11531 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVAZV010000060 DAVAZV010000000
VERSION     DAVAZV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11531
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.060"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..869)
                     /locus_tag="VQT46_001777"
     CDS             complement(<1..869)
                     /locus_tag="VQT46_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET2371752.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMKELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     KGEILEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQN"
     gene            1493..1675
                     /locus_tag="VQT46_001778"
     CDS             1493..1675
                     /locus_tag="VQT46_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2371753.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            1685..2050
                     /locus_tag="VQT46_001779"
     CDS             1685..2050
                     /locus_tag="VQT46_001779"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET2371754.1"
                     /translation="MPNSENTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            2047..3237
                     /locus_tag="VQT46_001780"
     CDS             2047..3237
                     /locus_tag="VQT46_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET2371755.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RNGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     NLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(3752..4744)
                     /locus_tag="VQT46_001781"
     CDS             complement(3752..4744)
                     /locus_tag="VQT46_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371756.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQPNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            4904..6658
                     /locus_tag="VQT46_001782"
     CDS             4904..6658
                     /locus_tag="VQT46_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371757.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAVLTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIVTPILVLVLGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAEVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAIIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            6642..8363
                     /locus_tag="VQT46_001783"
     CDS             6642..8363
                     /locus_tag="VQT46_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371758.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERIHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILIDGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            8374..9003
                     /locus_tag="VQT46_001784"
     CDS             8374..9003
                     /locus_tag="VQT46_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET2371759.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLSLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALIALGAFLGGILGAYIGKALLKKHFSNGLYCVGYFTPCLILWCYLN"
     gene            8904..9461
                     /locus_tag="VQT46_001785"
     CDS             8904..9461
                     /locus_tag="VQT46_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET2371760.1"
                     /translation="MYRQGSIEKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIP
                     IVIRMFILPFMAASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKN
                     IKMAMRVRGINFKNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRV
                     KIQLIDFVYVLAVAGLIVGGLIWLK"
     gene            9449..10813
                     /locus_tag="VQT46_001786"
     CDS             9449..10813
                     /locus_tag="VQT46_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371761.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGSGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDILEIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDESSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFIFFDEPSSGIDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         4213 a         1628 c         1953 g         3737 t
ORIGIN      
        1 aagttttgtt tgatggcttc aaacttttca gaactttcaa gataggcatc cacagccgcc
       61 ttgtagcagt tggttactgt tgatacgtag tgaatagact tcatacgtcc ttcgattttt
      121 agactgtcca caccattttc aatcatatct ggaatgtggt caatcataga catatcaacg
      181 gctgacattg aaaattcttc tagaatctca cccttcaaac tcttacgttc tttcccaaat
      241 ggcatatcgt aaaggtcgta tttccaacgg catgactgag aacacccacc acggttggca
      301 tcacgcatac tcatgtggtt tgaaagagta caacgtccag agtatgaaat acacatagct
      361 ccatggacaa aggcttcaat ttcaacatct gtacgtttgc ggatttcagc taattctttc
      421 attgaaacct cacgtgctaa aacgacacga gtcaagccta gctctttcca gaactcaagg
      481 gtttcatagt tagtggcact ggcttgggta gaaaggtgga tttcaaggcc tggtgcttca
      541 gtcgctgcaa tcataatcaa ggctgggtca gatacgataa ctgctgcaat cccgatatca
      601 cgcagtttac gaaaccactc accagcacca gcttcatttc cttcgtgcat aaccatatta
      661 gccgctacat agaccttggc accatacttg gccgcaaact gcacgccttc ttccatctgt
      721 tcgaaagtaa agtttcccgc acggctacga agaccatagg cctgaccacc gataaagaca
      781 gcatctgctc catactgaac agctaccttt agcttctcta aagtccctgc aggtgataaa
      841 acctcaggac gttttaatgt ttttgtcatg atttctccta tttgcaatat aaaagtttga
      901 catttttcct tctcatttta tagtaaataa aggataaaat caagcctaga cggattgttt
      961 tgacaattct aatcttttag actttgcata ataactatta aacagtcgaa aattacccca
     1021 gttttaacaa gtagtcaaaa agtctaaaaa agtaaaaacc agtatcccaa gatactgact
     1081 cgtaaaaata tataaattag tccttagatg actactccca ctctgttgct cctataatgg
     1141 aaaaggattg atacagtcta gaatatcgct tttttattta ttattctgat ataaaactgt
     1201 tagaattgat tttttgtttt atacccaaat atgaatagag acgtagctaa taagttgaat
     1261 aacatatttg gaaaaatgag aaatagcaat attactagaa cttttagaaa caatcaatat
     1321 ttaaaaagaa aaaagctcaa agaatttatt aaaccatgtt ataatagata tagctataat
     1381 tttatttata acaagaggat agaaatgacc gaattagaaa gaaaaaatcg aaaaattagc
     1441 taagaaatat tctgataact taaacatcaa agttcaagag agagttcgtg aaatggcaaa
     1501 tgataataag agccattatt tgatatacag agttttaggt atttcatttg aagaaggaga
     1561 aaatatcgat ttgtatcaaa ataaaggtcg ttttttatac aaatatgctg gttcattttt
     1621 agaagaagct gcagtactat cctttaacga aaaatttggt acagaaaata cttaaaaagt
     1681 taacattcct aattctgaaa atacaaaacc taagactttt gaaattgatt gtttagtcgg
     1741 agaaaaacac gcatacgaaa taaaatggtg ggatgcaact acagatggag accatataac
     1801 taaagaacac actagaataa aagttattca taacaaagga tatataccaa ttcggttaat
     1861 gttctactat ccaaatagaa ctcaagctat aaaaattcag caaactttag aaacattgta
     1921 taacggtatt ggagggaaat attattatgg agattctgcc tgggaacatt taagagcagt
     1981 gaccggtatt gatttactta gtattctaac agatattgca aataaaaaaa caggggtaaa
     2041 atcaaaatga cagtattaaa aggagataac ttagaaatat taaaaactat tgaatcctca
     2101 agtattgatt taatctatat ggaccctcct ttctttacac agaaaaccca aaaattatct
     2161 aataacaaaa atattatgta ttcattcgaa gatacgtgga cttcgattga ggattacaaa
     2221 gaatttttgt ctgtaagatt agaagaatgc aaaagagtgc taaaaaatag tggcagtatt
     2281 ttcgttcatt gtgataaaat tgcaaatcat catattagat taattttaga taatatcttt
     2341 ggagcagata tgtttcaaag cgaaattata tggaactata aacggtggtc taattcaaaa
     2401 aagggattat tgaacaatca tcaaaacatt tacttttatt caaagtcaaa agattttaaa
     2461 tttaatacaa tttttacaga gtattcttct actacaaata tcgaccaaat actagtagaa
     2521 cgaaaacgaa atggaaactc taaaactata tataaagttg ataataatgg taactatatt
     2581 ctagcaaaag agaaaaatgg agttcccctt tcagatgttt ggaatatacc atttcttaat
     2641 ccaaaagcta aagaaagagt aggttatcct acacaaaaac ctattctgtt attagaacaa
     2701 attataaaga ttgctactga taaaaatgat atagttttag acccgttctg tggaagtgga
     2761 actactttag tagcctccaa gattttgaat agaaattata tggggattga tttatctgag
     2821 gaagctatca atataactca gcaacgtctg gaaaatgtta taaaaacaag ttcaaattta
     2881 ttgaataaag gaatcgaagc atatagaacc aaaactgagg aagaggaaaa cattcttaaa
     2941 ttattacagg caaaaattgt tcaaagaaat aaaggaattg atggtttttt acctaaacat
     3001 tttcaaaaaa aaccgatacc tataaaaatt caaaaaaata atgaatgtct gaatgagagt
     3061 atctctttat tacagaatgc tataaactcc aaaaaacttg attttggagt agttataaaa
     3121 actcattcag ataatttatt atttgatttt gatacgattc ctgaaaatat aatagtagtt
     3181 gaccattttg aacttacaat cgaaaaatgg ttaagtaaaa gtcaacagtt actatagttt
     3241 gcaaattatt tacagaaaga acaaaaaatg ctctgaaaca ctgatttcaa ggcatttttt
     3301 gttagtttaa aattactccc attcttcttt tccaaacgta caatatatcc aaaaccattc
     3361 aaaatactag attctatttt ttataatatc actaaatcca cctaattata ggacgttttc
     3421 agatttttag tcccgtccca gtcccagtac cggagaaata ttgttttaat ataatatctc
     3481 tttttgtctt ctaagctctt aaaagcaaaa gaacaagtaa agagtcaaga caaggataaa
     3541 aagtccatat tagggcaaat aaaaagcttt aagacagatg acaaatctaa gtcaaataag
     3601 aaagaccata gcaaaggtgc agagagataa atattggcgg tcttcggact gcctttattt
     3661 ttttatccat ttttcaaatc aaatttattc agactatata tgcacatata cacttaaatt
     3721 catataaaaa catggcttgt aaaaaattac tttaatcaca ataatcgcat ttaaaattgt
     3781 gatgtttgca agctaaatta cggacttcac ttggaagttt tcccttgtat cttttataat
     3841 agatagaaaa tttgctggca gatgaatatc caacagattc tgctatctct tttataggta
     3901 gttcagtgtt taaaagaaga gtttcagcta cattcattct ttttctttga gtgtactctg
     3961 taatgctttg acaatatttt tccttaaata aattttttaa tttagtacca ctcattttag
     4021 atattttttc aagcgtgcct tgatttacat tcgttgcaaa atgatcatct aagaatcttg
     4081 ctacatcttc aagtgcttta tcatcatcaa tttcaatttt atattttttt ctatttaagt
     4141 atgtgtcaat tactatactt atccattcat ttgcctttgc tttaaagaaa aaatcagcgg
     4201 caggagcgtc catcttacaa tttaatattt ccattgccac tctttctaag gcctttgtaa
     4261 gtattatttg attcggttga agcaaggttg aataaaaaga ttctggatta atgttaatag
     4321 atgctaaatg tttttctatt agctcttttt taaaaccaat ggaaacagca agataacaac
     4381 aattctcgtg taataaaaaa acaaaatcat cttttatatt atcaaaatca aaagtacata
     4441 aagagtttgc ggtaatagtt tgatacggat taaacttttc tccgtttgca ctgacaatgt
     4501 aacttgaata aattgaaaca tagtctgaca tactataagt gctattttga actacttcct
     4561 ctttgatata aaaatcatgt atatcgataa tgaagctgcc tccttcataa aaccaatata
     4621 ggccttctgc ataagttgaa ttctcttttt tccaacaaaa tgtatgacct gcacttgaat
     4681 acttctcatt gtttttacat tcatctactt tcatataatc ttttacaaaa tcataatatg
     4741 acataacaca ctatcccttt tagacaatat tccaattagc cttattaatt caaaactatt
     4801 gtattagtaa ttataacaga tgtataatag aaaagcaatg atagatatta tcaattaagc
     4861 gaatttatat ctaaaaggga tattaaagaa aggagatatg cttatgaaga tttacaaaaa
     4921 actatttgct tatgtccaag ataagaaata tcttggggtt ttggccataa ttttttctgc
     4981 tatatctgct gtacttacag tatatggata ttatttaatc tacaaatttc tagataagtt
     5041 aataattaat tcaaacttat ccggtgcaga gagtatagca ttaaaatctg ttattacact
     5101 aacaagtgga gcgatatttt attttgtctc aggaatgttt tcacatatct tgggatttag
     5161 gcttgaaaca aatttaagaa aaaggggaat cgatggtctg gaaaaagcaa gttttaggtt
     5221 ctttgactta aatccatctg gtcaaataag aaagatcata gatgataatg cagcacaaac
     5281 tcatcaggtg gtagctcaca tgattccaga tagctctcag gcaatagtca cacctatact
     5341 tgtccttgta cttggcttta tagtaagtat aagagttggc ataattttgc ttgctcttac
     5401 tataattggt ggcttaattt taggggcaat gatgggcgag caagaattta tgaagatata
     5461 ccaagaatcc ctatctaaac taagtgctga aactgttgag tacgtgagag gaatgcaagt
     5521 tgtaaaaata tttaaagcaa atgtagagtc ttttaaaagc ttttataagg cgataaaaga
     5581 ttactcaaag tatgcttatg attattccct atcttgtaaa aggccttatg ttttgtatca
     5641 atggttattt tttggactga ttgcaatttt aattattcct atagtttatt ttatgactag
     5701 cttagctagc gcagaggtga ttttacttga gcttatcatg attttatttt tatcaggagt
     5761 tctctttgtt tcattcatga gaatgatgtg gtactccatg tatatttctc aaggaaatta
     5821 tgcagtagat actttagagg cgctttacga agatatgcaa aaagacaaat tagtgcatgg
     5881 taatgtcaat aattttaaaa actataatat agaatttgag aatgttagct ttgcttataa
     5941 tgataaagct atcattgaaa atttatcctt taatttagaa gaaggaaagt cctacgcact
     6001 tgtcggttca tctggatcag gcaaatcaac agtagcaaaa cttatatcag gtttttacaa
     6061 tgttaataaa ggaagcataa agataggcgg gatagcaata agtgaatatt ctgacgaagc
     6121 cttaattaaa gccatttcct ttgtttttca agattcaaaa ttattcaaga agagcattta
     6181 tgataatgta gctttagcta ataaagatgc gacgaaagat gacgttatga gagccttaaa
     6241 attagcagga tgcgatttaa tattagacaa attcccagaa agagaaaata caatcatagg
     6301 ctcaaaaggt gtttatttat ccggtggaga aaaacaaaga attgcaattg ctagagcaat
     6361 tttaaaggat tccaaaatta ttattatgga tgaagcatca gcatctattg acccagataa
     6421 cgagtttgaa ttgcaaaaag cttttaaaaa tcttatgaag gataaaacag ttatcatgat
     6481 tgcacacagg ctatctacaa ttaaagacct tgatgaaatt attgtcatgg atagtggaaa
     6541 aattatagaa agagggtctg acaaagaatt aatgtcaaaa gatacaaggt ataagagcct
     6601 gcaagagatg tttaacagtg cgaatgaatg gagggtttca aatgaaagag ttttataaaa
     6661 aaagatttgc tcttacagat ggaggagcaa gaaatttaag taaagcaaca ctggcttcat
     6721 ttttcgttta ttgtataaac atgcttcctg ccatattact tatgattttt gctcaggaag
     6781 ttttggaaaa tatgggcaaa agcaatggct tttatatagt attctcagtt ttgactttga
     6841 tagcaatgta tattttgctt tctatcgaat acgataaatt atataacaca acctatcaag
     6901 aaagtgcaga tttaagaata aggacagcgg agaatttatc aaaattacct ctatcttact
     6961 tttctaaaca tgacatttcc gacatttcac aaacaatcat ggctgatatt gaaggcatag
     7021 agcatgcaat gagccactca ataccaaagg tgggcggcat ggtactgttt ttcccattaa
     7081 tatctgtaat gatgctagcg ggcaatgtca agatgggttt agctgtaatt attccatcta
     7141 ttttaagctt tatatttata cctttatcta aaaaatatca ggttaatgga cagaatagat
     7201 attatgatgt cttaagaaaa aactcagaaa gctttcaaga aaatatcgaa atgcaaatgg
     7261 agattaaagc atataattta tcgaaggata ttaaagatga cttatataaa aaaatggaag
     7321 atagtgagag aatacactta aaggcggaag taactacaat tttaactttg tctatatctt
     7381 caatatttag ctttatatct cttgctgttg tgatatttgt cggcgtaaat ctaattatta
     7441 ataaagagat aaattctctc taccttatag gatatttact agctgctatg aagataaaag
     7501 actctttaga tgcatctaaa gagggcttga tggaaatatt ttatttatcg cccaaaatag
     7561 aaagattaaa agaaattcaa aatcaagatt tacaagaagg cgatgactat agcttaaaaa
     7621 aatttgatat tgatctaaaa gatgttgagt ttgcctacaa taaagacgca aaagttttaa
     7681 atggtgtaag ttttaaagct aagcagggag aggtcactgc tttggtaggt gcaagtggct
     7741 gcggtaaaac aactatcttg aaacttatat caagacttta tgattatgac aagggacaaa
     7801 tcttaatcga tggcaaagat ataaaagaaa tatcaacaga atctcttttt gataaggtct
     7861 ctatagtttt ccaagatgtg gttctcttta atcaaagcgt tatggaaaat attagaatcg
     7921 gtaagcaaga tgcaagtgac gaagaggtta aaagagcagc aaaacttgca aattgcacag
     7981 attttataga aaaaatggat aaaggtttcg atacagttat tggtgaaaac ggagctgagc
     8041 tatcaggagg agaaagacaa agattatcaa tagccagagc cttcttaaaa gatgcgccga
     8101 tattgatctt agatgagata acagcaagcc ttgatgttaa caacgagaaa aagattcaag
     8161 agtctttaaa taatttagtt aaagataaaa ctgttgtaat catttcacat agaatgaaat
     8221 ccatagaaaa tgcagacaag atagtagttc ttcaaaacgg aagagtagaa agcgaaggta
     8281 agcatgaaga gcttttacaa aaatcaaaaa tttacaaaaa tttaatagaa aagacaaaaa
     8341 tggcagaaga atttatttat taggaggact acaatggata ataaaaaatt aaaagtaaaa
     8401 gatttagtaa gtatcggtgt ttttggcgta atttattttg ccttcatgtt tggagttggt
     8461 atgatgggct tgattccaat attgttctta atatacccga cagtattagc catagttgca
     8521 ggaactgttg ttatgttatt tatggctaag gttcaaaagc catgggcact atttatattt
     8581 ggtatgatat caccacttgt gatgtttgca gctggtcata cctacgtagt tgtggtttta
     8641 tcacttatag taatgataat agcagaatta attagaaaga ttggtaatta taattcattt
     8701 aaatacaata tgctttctta tgcaatcttc agcacatgga tatgtagctc tttaatgcaa
     8761 atgcttttag caaaagaaaa atatatggag tggtctttga tgacgatggg aaaagattat
     8821 gttgatgtat tagaaaagtt aataacttat cctcacatgg ctttaatagc cttaggtgct
     8881 ttcttaggag gaattcttgg agcatatata ggcaaggctc tattgaaaaa acacttttca
     8941 aatggattat attgtgtggg atactttact ccttgcctaa ttttatggtg ttatctgaat
     9001 taaaccctat agttaagatg tttttgagta tacctattgt tattagaatg tttattttac
     9061 catttatggc agcaagcttt atgataaaga cctcggatgt aggcgcaata atttcatcga
     9121 tggataagct taagatttca aagaatgtat ccatacctat tgcggttatg tttagattct
     9181 tcccatcttt taaggaggag aagaaaaaca tcaaaatggc tatgagagta agagggataa
     9241 attttaaaaa cccagtcaaa tatcttgaat atgtttctgt gccactactc attatatcat
     9301 ctaatatatc agatgacatt gcaaaagcgg cagaaacaaa ggcaatagaa aatccaattg
     9361 ccaagaccag atacattcgc gtaaagatac agctaattga ttttgtttat gttttagcgg
     9421 ttgctggact tattgtggga ggcttaatat ggttgaaata aaaaatttaa gtcttgatta
     9481 tggtgaagag catatattag atgatatatc actatccata gccgagggag agtgcgtgct
     9541 atttacagga aaaagtggaa gtggtaagtc atctttaata aattcaatca atggactagc
     9601 tgtaaggtat gataacgcaa agacaaaggg cgaaataatt attgatggta agaatataaa
     9661 aaatttggaa ctttatcaaa tctcaatgct tgtttcaact gtttttcaaa atcctaagac
     9721 atattttttt aatgtcaata cgacattaga attattattt tatttggaaa atatcggtct
     9781 tgcaagagaa gagatggaca ggcgtttgaa ggatatactt gagatattcc cgataaaaaa
     9841 tcttttgaac agaaatatat ttaatctatc cggcggtgaa aaacaaattc tttgcattgc
     9901 agcttcttat atagcaggta caaagattat agttatggat gagtcttcat cgaatttaga
     9961 tattaaaagc ataagtgttt tggcaaagat gctaaagata ttaaaagaga aaggcataag
    10021 cataattgtt gcagagcata gaatttatta tttgatggac atagttgacc gtgtattttt
    10081 aatagataaa ggaaagctta aaaaaactta tactagaagt gaatttttaa agctagataa
    10141 aaatgaatta aatgctttaa gtttaagaga taaagaatta agtaaattaa aagttcctta
    10201 tttaaaagaa ggtggagagt atcagataaa aaatcttagc tacaaattta ctgatgatga
    10261 gtgtttaagc ttaaaagata tttcgttcaa gcttgggaaa atttatggca taataggatc
    10321 caacggacga ggaaaatcaa cgcttttaag atgtttaata ggtcttgaga aaaaatcaaa
    10381 agaagaaatt tattttaagg gagagaagct atctaaaaaa gaaagactca aaaactcttc
    10441 acttgttatg caagatgtaa atcatcaatt attcacagat gaagtattca acgagcttag
    10501 attaggagta aagaattttg atgaagaaaa ggcgaaaatc attttaaaag atttaggcct
    10561 ggacgaattt attgaaaggc atccgatgag tttatcagga gggcaaaagc aaaggcttgc
    10621 aatagcatct gttatgtgca agacttctcc atttatcttt tttgacgaac cttcaagtgg
    10681 tatagattat tccaatatga taaaaatatc tgaactgatt aataagtata aaaccatgga
    10741 taaaataatt tttattgttt cccatgatat agaattttta aatgaagtgg cagatgaaat
    10801 ttttgaattg taaaatagag tctgttaaac atgtctatag aactggtaaa ttgtctaaaa
    10861 atttaaaaga tactaacaca tattgatatt tattagaaaa ttaacttcag gatttttaca
    10921 gtatttataa actttataat atgtatttat agtattaata atttccatat ctttagggaa
    10981 attatttatt tacttaccat aattaaagag atgagagata aatatcggca gtcttcggac
    11041 tgcctttatt tttttactta atttaatgca gtaaatcata cgattgaaag gaatctgcgt
    11101 tatatgctat aattaggtag ttaatctata catttagaaa ggtaaaatat agaattggag
    11161 aatgatatgg gattttcata taataaattg taaccaccca ataacgaagt ctattgaaaa
    11221 atctccagat tagtgaactc acggatagtt cctaatctgg agatttctta tttgcacttt
    11281 tcttgtacaa ctttagtcca tggtaaataa gcctctaaaa cctctttgtt tacgagagtt
    11341 tcctcgtttg gaagacattc tagaagatag gatagatatt tctcgctatt tataatggat
    11401 tgaaataaga tatgaacaaa tcgattagga aaggaaaatt gatttataga aatattttag
    11461 cagtcgatgc gtactgttat agattcaacg cactataatt gatgacgttt agctgtttcc
    11521 aacaaactca t
//
LOCUS       DAVAZV010000061        11358 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVAZV010000061 DAVAZV010000000
VERSION     DAVAZV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11358
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.061"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..134)
                     /locus_tag="VQT46_001787"
     CDS             complement(<1..134)
                     /locus_tag="VQT46_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371762.1"
                     /translation="MAYSTDFKQGALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     "
     gene            403..783
                     /locus_tag="VQT46_001788"
     CDS             403..783
                     /locus_tag="VQT46_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET2371763.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            882..1103
                     /locus_tag="VQT46_001789"
     CDS             882..1103
                     /locus_tag="VQT46_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET2371764.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            1120..1434
                     /gene="trxA"
                     /locus_tag="VQT46_001790"
     CDS             1120..1434
                     /gene="trxA"
                     /locus_tag="VQT46_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET2371765.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            1741..2274
                     /gene="queF"
                     /locus_tag="VQT46_001791"
     CDS             1741..2274
                     /gene="queF"
                     /locus_tag="VQT46_001791"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET2371766.1"
                     /translation="MKHQSALVVFSGGQDSTTCLFWTMQHYETVEAVTFAYGQHHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
     gene            complement(2528..3196)
                     /locus_tag="VQT46_001792"
     CDS             complement(2528..3196)
                     /locus_tag="VQT46_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET2371767.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLSN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(3307..3861)
                     /locus_tag="VQT46_001793"
     CDS             complement(3307..3861)
                     /locus_tag="VQT46_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET2371768.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLFDHLGNPSPEIRNVLLNQGL
                     HYLSKEKDTRGFSSQYGWVHAFAHGADLLTEVVCHPGFPKNRVHEVFEILGQLFKRMS
                     IRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVDFPIEEREDFYKFSNFRSCLVE
                     VYVQLDQRNSLQDELKEAIQSFQY"
     gene            complement(4107..5903)
                     /gene="pepF"
                     /locus_tag="VQT46_001794"
     CDS             complement(4107..5903)
                     /gene="pepF"
                     /locus_tag="VQT46_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET2371769.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYGFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDATLTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKHSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIISYSAELGE"
     gene            complement(5914..6657)
                     /locus_tag="VQT46_001795"
     CDS             complement(5914..6657)
                     /locus_tag="VQT46_001795"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET2371770.1"
                     /translation="MQQYFVKGSAVSPVTIEDRETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFITQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNVVPSIHLFENKADFLAQLDQ
                     FDRILVAYEEAAKEGEAAALIKAVTGLEKGAKLLFIFGPEGGLSPAEIENFEAKGAVL
                     AGLGPRILRAETAPLYALSALSVLVELEK"
     gene            complement(6659..7609)
                     /locus_tag="VQT46_001796"
     CDS             complement(6659..7609)
                     /locus_tag="VQT46_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET2371771.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYMGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDMTVVEADLQARLAELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNTG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMIQGEWNACVFKKTKDISGVIGG"
     gene            complement(7747..8175)
                     /locus_tag="VQT46_001797"
     CDS             complement(7747..8175)
                     /locus_tag="VQT46_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2371772.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            complement(8156..9244)
                     /locus_tag="VQT46_001798"
     CDS             complement(8156..9244)
                     /locus_tag="VQT46_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET2371773.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            complement(9263..9733)
                     /locus_tag="VQT46_001799"
     CDS             complement(9263..9733)
                     /locus_tag="VQT46_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET2371774.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     VLFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            complement(10024..10476)
                     /locus_tag="VQT46_001800"
     CDS             complement(10024..10476)
                     /locus_tag="VQT46_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET2371775.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            complement(10513..10692)
                     /locus_tag="VQT46_001801"
     CDS             complement(10513..10692)
                     /locus_tag="VQT46_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HET2371776.1"
                     /translation="MPMTQKEMVKLFTAHGWIKTRGGKGSHIKIEKQGERPITILHGE
                     LNKYTERGIGKQAGL"
     gene            complement(10829..11008)
                     /locus_tag="VQT46_001802"
     CDS             complement(10829..11008)
                     /locus_tag="VQT46_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371777.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            complement(11173..>11358)
                     /locus_tag="VQT46_001803"
     CDS             complement(11173..>11358)
                     /locus_tag="VQT46_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371778.1"
                     /translation="IFTKQIRHWILSDQVISGKRKLFFREDTPKEILDLYENIKSKLD
                     FAYQEVHSNNGLKKYEK"
BASE COUNT         3418 a         2625 c         2041 g         3274 t
ORIGIN      
        1 ttgtttacgt ctttcttttc ccacgtgaag agagttctga cgccaacacc aaaaaacttg
       61 gctgcctcga catgactgtg cccctctttg atggaatcta atgctccttg tttaaaatca
      121 gtactatatg ccatagcttt attagaccat gcttatttta aactaagcaa ctatagatag
      181 agaaatgaaa taaaatctaa attcgaatgt gataaggagt tagaaattga aacaatagga
      241 ttcccccatt attcacacaa aaataaaacc actaaaaaac agagcttgcc agcattcttg
      301 aaaagtagta taattattgc atgcgcaatc atcttgtgac gcagagactg cccgttaatg
      361 gactttcttc tatattatga ctctaaaaag aaaggagaca ctatgaccta tttggaaaaa
      421 tggtttgact tcaatcggcg tcagaaagaa attgaaagtc tcttggaaga gaccattgcc
      481 caacagagcg agcaaagtct gaccttgaaa gagttctacc tgctctacta tctggacttg
      541 gctgaagaaa aatctctacg ccagattgac ctgccagata aacttcatct gagcccgagc
      601 gcagtttcta ggatggtggc tcgcttggaa gctaaaaatt gcggtctact cagtcgcatg
      661 tgttgccatc aagatagacg ctctagtttt atctgcctga caaatgatgg gcaaaagaca
      721 ctggcctcgc tacaaaagac tgtcgaagaa agcttggaag caggtttgga tttcttgatt
      781 taagatgatt ttaaaaaaag ttgcgtgcgc aatcattttt cttgacattc tcttttataa
      841 ggagtaaaat aaagttagca ttaaacaaag gagttttaaa tatgattgaa attacctata
      901 tagatgccag caagaacgaa agaactgtga ctttcgagtc ttatgaagac tttgaacgtt
      961 cacaacaagc ttgccttatc ggcgtcgcag actactaccc tgtccaaaaa ttaacttaca
     1021 agggtcataa tttggactac catgggactt atggagatat cttcttctat ctcatgaaac
     1081 aagatttaag ccaatataac taaaaaaagg agaaatacaa tggcaaaagc aattacagat
     1141 gcaacattcg aacaagaaac aaaagacggt ttggtcttag tagacttctg ggcaacttgg
     1201 tgtggtccat gtcgtatgca aggtccaatc ttggacaaat tgtctgaaga actttcagaa
     1261 gatgtcttga aaatcgttaa aatggacgtt gatgaaaatc caaacacagc tcgtgctttt
     1321 ggaatcatgt ctattccaac tcttctcttc aaaaaagacg gccaagttgt caaacaagtt
     1381 gcaggtgttc acacagcaga acaaatcaag gccatcattg ctgaattgag ctaatcaaac
     1441 gagagaccaa gtactttctt tggtctcttt tttcttgccc tttgccattt ttcaaaaaat
     1501 atgctagact atagtagatt gaaactagaa tagtacacct ctacttctaa aacattgtta
     1561 aaaatcgatt tgactgtcct gatcgatttg tcctgttttt atttcatttt actatataag
     1621 tagaatatta cgatgtttgg gatatgccat cgctaaaaaa aaactcgatt tggtattttt
     1681 tagttcccta atgggagctt tttgcgtgct ctgaacattt cccattttgg aaggagtact
     1741 atgaaacatc aatcagcctt ggtcgtcttt agtggcggtc aagattcaac aacctgcctt
     1801 ttctggacca tgcaacacta tgaaacagtc gaagctgtca cctttgccta cggccaacat
     1861 catcacctcg aaattcaaat tactagagaa atcgctaagg aacagggcat tcgtcaccat
     1921 atcctcgata tgtctctgct gggacaaatc actgctcagc cagactttgc gacgattcat
     1981 atttcctaca ttcctgacaa gctctgtgtc gagtcaaaat ccctcaaact atatctattt
     2041 agctaccgaa accacggaga tttccacgaa aactgtatca acaccatcgg gaaagacttg
     2101 gtcaacttgc tagaccctcg ctatttagaa gtctggggaa aattcactcc gcgcggtggc
     2161 atttcaatcg acccctacta taactacggt aagcaaggaa ctaagtatga gggcttggca
     2221 gaacaacgcc tcttccaaca cgacctttat ccagagaaaa ttgacaaccg ctaaagtcat
     2281 actcaatgaa aatcaaagag caaactagga agttagccgc aggttactca aagcagtgtt
     2341 tgaggttgta gataaaactg acgaagtcag atcaaaacac tgttttgagg ttgtggatag
     2401 aactgacgta gtcagtaacc atacctacgg caaggtaaag ctgacgtggt ttgaagagat
     2461 tttcgaagag tatcatacga aaaagccctg ttcctcaaga tgaggagcaa ggctttttga
     2521 gtttcaatta ttcttctgtt ccaaggaaat tttttgcaac aagggctgca agaactccac
     2581 cagcgattgg tgcaaggatg aaaatccaaa cttgttgaag ggctgcgccg cctaccaaga
     2641 cagctggtgc caagctacga gctgggttta ctgaaagtcc agtaatcttc aatccgacaa
     2701 gaatcatcgc catcaatgac aaaccgatta ccaaaccagc aatcgcgcca ttgcccttgc
     2761 tttctgaagt cacagtcatg ataaccaata caaacaagaa agttgcgatg acttcaaaca
     2821 agaaaccacc aaagacagtg acaccgtttg ccaaggcatt ttcaccaaga ctagcagttg
     2881 acatacctga attactcaag aggaagaaga ctgcgccaga agcgatgaaa gctccaacaa
     2941 cctgaccaag gatgtagttt acaagttctg aagatgacaa acgtttgttt acaaacatag
     3001 caatcgaaac agccgggttc aagtgagcac ctgaaacagt tccgattgag taggctgcca
     3061 ccacgattgc caaaccaaag gcaaaggcga ttccaaggtg accaaggcca tcaagaccat
     3121 ttccaaaaac aacagctcct gttccaacga acacaagcat gaacgtaccg attaactcag
     3181 caacaaattt tttcattttc tttctccttt tttcaaaaac tagatactag tctatcaaaa
     3241 gtaggaaagg gtttcaagaa aattgattgg aaattttttg aaaatcatag aactattagc
     3301 taatctctag tattgaaaag actggatagc ttctttcaac tcatcttgta aactatttct
     3361 ctggtcaagt tggacataga cttccaccag acaggatcta aagttggaaa atttgtaaaa
     3421 atcctccctt tcttctatcg gaaaatcaac agtttttatc caagaagcta cttgttcttg
     3481 cgctaacttc ccttgtaaaa taggttcata gatcactctt gctaaacgcc aatcctcatc
     3541 atctgtaaag cgaatcgaca ttcttttaaa taattggcca agtatctcaa atacttcatg
     3601 aactctgttt ttaggaaagc ccggatgaca aaccacctct gtcagtaaat cggctccatg
     3661 tgcaaaagca tgaacccaac catactgact tgaaaaaccc cttgtatcct tttcttttga
     3721 aagatagtgc aagccttgat ttaaaaggac attacgaatt tctggagaag gatttcccaa
     3781 atgatcaaac aaccactgga tttcttcctg gttataattt ggtttttctt ctgctatttt
     3841 tcttagtaaa tcttgataca tggtcaatac ctctacattt ctagcaactg ttcaaaaagg
     3901 cagtcttaaa tgactcaata ttgaattctc aattaaatac aatctgatat aaaatgacgt
     3961 aaataactat caataccagt tctacagtaa gttcaaattt aacatcacga tcttcaacga
     4021 catttttgaa aatagctaca actaagacaa atagaatgac gcttaacaag cccataaaca
     4081 tcattctaaa aaatttttct attcccctac tctcccaact cagcactata ggagataatc
     4141 tggtcaactg tgtcagacaa gaattggatg gtatcacgga gtggtttgtc tgttgaaata
     4201 tcagcaccga taatcatggc tgactcaagt ggtgtcttgc taccacctga tttgaggaga
     4261 ttgagccagt cttcagctcc agtttcagaa tgttttagat gaaggtaacc agcagtcgag
     4321 ataactagtc ctgctgagta agtgtaacta tacaagccca tatagtagtg agcttggcgc
     4381 atccaagtca gagttgcatc atcgtcaatt tcaatagcat ctccccagaa atccgtcaaa
     4441 acttccttca taatgctgtt gagcttgctt gctccaaagg tctccccttc ttcaatcaat
     4501 gtatacacct tacgctggaa ggcggcttcc aagaggtggg tgataaagtt atggaagtag
     4561 gtgtctgtca agcgatgagc cagagcgaag cgtttttgac gtgggtcatt agactggttc
     4621 tccaagtaat cactgagtag caattcattg aaggttgacg gtgcttcaac atagtaggtc
     4681 gacatatggg cattgaagta actttgatga ttgtctgaaa agatgaattg accagaatgc
     4741 ccgatttcat gaatcaaggt atagacatcg ctcaaacggc ctgtccagct catgagtaca
     4801 taagggtgta cgcgatatgg gtccgccgca taaccaccgg aatccttgcc actgttagca
     4861 gcaaagtcca cccagcgctc ttcttggtaa cgagcaactt cctgacaata ttcttgcccc
     4921 aaaggttcta ccgacttcat gaccaaatca taggcatcgt caatagtcac ttcaggattc
     4981 agggcgctgt ccaagtccaa tttccagtct gcaaaggtca tcttttcaag accatttacc
     5041 ttggcaacat gcttgaggta tctctgagcg actggtgcaa agtccttcat gatgaggtca
     5101 atctggcggt caaacatgac acggtccact tcttgttcag ctagaagata gtcaaagaca
     5161 gagtcgtatc ccttcatatc agccaagagt ttttcagact tgacctgagc cagataggct
     5221 gctgcagccg tattttggtg cttacgaagt ccctctgaga aggaacggaa ggatttctca
     5281 cgaacctcag catcctcatg gttttggtag aaattctcat aggtcacaaa gctgtttttg
     5341 taggtcttgc catgggcttc aaagtcagcc atttcaaaat ccccagctcg catcttagta
     5401 taaatgtcct gcggactgta gaaaacttca ccgagatttg tcaaggcctt ctccacatct
     5461 gcccctaagt agtgggcttt tttgatttta gcctgacgaa tggcagctgt taaatgtggc
     5521 aatttaccca aacgatccaa gacttcctcg tctgctgcca ccaaggcatc gtcaaaaaag
     5581 gtcaaggcta cgctggcatc tgtttcaaat tccatcccag cttgagcaat atttgcaaat
     5641 tcgtcattgc tatagtccgt cgtctgaggc ataaaaccat agttgccaat atggctcatc
     5701 tgaatgtaga tctgttccaa ttccgcaaag gccttctcga aatcctcaaa agtgtgaaga
     5761 ttgcccttgt aatcacggct aaactggttg atgtcttcgc gagctttctc gattgcacgc
     5821 aagaaatcct cacggtcttg gtatagagct gttaaatccc aaagttcctt ctctggaaat
     5881 tctgaacggt gtttttgttc cattttcttc ctcttatttc tctaattcta ctaaaacact
     5941 aagggctgat aaggcgtaaa gcggtgctgt ttctgctctt agaatgcgag ggccaagtcc
     6001 tgccaaaaca gctcccttag cttcaaaatt ttcaatttcc gcaggtgaca gaccaccttc
     6061 tggaccaaag ataaagagca atttggctcc tttctcgagt ccagtaactg cttttataag
     6121 agcagcggct tctccttctt tggccgcctc ttcataggct actaagatgc ggtcaaactg
     6181 gtcaagttgg gctagaaagt ctgctttatt ctcgaaaaga tggatacttg gaacaacatt
     6241 acgcttactt tgctctgctg ctccaagagc aattttttct agtttttcaa cctttttacc
     6301 caatttcttg ccatcccact tagcaacgga ccaatcggca gggaaggccc aaatctggct
     6361 ggcacctagt tccgtcacct tttgagtgat aaactccaac ttatctccct tgggaaatcc
     6421 agatgcgatg gtcacttgga ctggtagttc cacattgtca tttaattctt ggaccaactc
     6481 aaactgacga ttttccatat ccagcacgcg cgccaagcgc ttgatgccat catcaaagac
     6541 taaggtaacc tcatcctctt ctttcaagcg cataacctga aacatatgct tgctggtttc
     6601 cctgtcctcg atggtgacag gagagactgc actccccttg acaaaatact gttgcatgct
     6661 agcctccaat cacacctgaa atatccttgg tcttcttgaa gacgcaggca ttccattccc
     6721 cttgaatcat atgggtttca aggaaaaatc cagctgactc agccgactgg cgcaccatgt
     6781 cccacttgtc cttgataatg ccactcatga tgaggtagcc ttcatccttt accaagcgat
     6841 aagcatcctc cgtcagatga atgagaatat ccgccaagat attagccacg atgacatctg
     6901 cttcaatctc aactccctta agcaagtctc ctgctgctac atggatattt tccataccag
     6961 tgttgagctc aatattttcc tgagcgacac gaaccgccac atcatccaag tcataggcga
     7021 aaatctcctt ggcacctagg agtgagcttg caatagaaag aacccctgaa ccagtcccca
     7081 catctagcac cgtttcgcca ccacgaagaa cctgttccaa ggcaaaaagg ctcatcttgg
     7141 tagttgggtg ggttccagta ccaaaagcca tgccaggatc cagcttgata attttttctc
     7201 ccgcagtcgc ctcatagtct gtccaagagg gaacgatggt caaatcatga gtgatgcgag
     7261 caggttcata gtatttcttc cagttgtctg cccagtcttc ctcagccaag gcagtcgtac
     7321 ctatttttaa ctctcccaaa tccataaaat ccgtcaattc tgctaagcga gcctgcaagt
     7381 ccgcctcaac cactgtcata tccaccgtgt cagggtagta ggctgtcact acgatttctt
     7441 cttgctgctc cacctctggg aaaatctcgc caaaacgatc cacatttccc atatagtcca
     7501 tgctgtcttc aatcgcgact ccttgcgctc ccagctcaat caagagattg gaaaccaact
     7561 cctctccctc acgcttcact gtaactttta actcttgcca tgtttccatt attaagatac
     7621 caagcccgta aaacacaaaa ccaaaatagg aaattctctg aagacgcttg tgtctaagag
     7681 aagtttatct ttttggcaca gtgtttaggg cgggttcagt ttagaaatgt aactgaacca
     7741 tcctttctaa tcacttactt ttaaataatc ttttaatctc tcttgcaact gaggcacaac
     7801 ttgactggaa ctaagaaatt cctcaacatt catcagctga tagccctgtc cttcatctcc
     7861 gaagatgata ttgtcaaatt gttcttgtct tagctgacca accataaaga ccgatttctt
     7921 gcctttaaaa attacgctag gataaatctt gctccaaagc agacagtctt catctaaatg
     7981 aattcccagt tcctcataaa cttcacgccg agcgcattca aaagggcttt cgtccccttc
     8041 acggccacca cctggcaact cccacatgtt gggacaaggg atatcgtcct tgtcatcacg
     8101 caaaatcgtc agtagcttat ccccacaaaa gagggcaatc ttgcaacctt ggaaatcaga
     8161 aatttctagt tccatcttca gttccttcta acatttcctt ttccagctct gctaacaagt
     8221 tttcataata gcgtttctcg tccctcaaca ttcgactact atccattttc tgtctagcaa
     8281 tcttgagagc cttacgagtt cgatctacat ctttcttcac ctttaattga taccaggctt
     8341 gtatcacttg aagattggac agtttgagag acagaaacga tttgacctgt cgaatactag
     8401 catattgctc cgcttgctca aaatctcctt ccaacaaggc gatatgaagc agggatagtt
     8461 gggcaactgt ctgcatcatc ggagtagttg tcctctcaag taatgcttga aactgctgtt
     8521 tagctacttc ttccttccct tccaaaatgg aaacttcacc ttgcatacct aatacaccat
     8581 ccgcaaaact ccctcgtgca tcctcaggaa ctgcttgaac aaagtctttc aaatcatatt
     8641 cttgaggagc cagcaaagtt tgagcagaat gtctcaatac caggtaggcg tatttggtat
     8701 tttcagggtg ttgtagtaat tcccaaattt ttgctccatc ggtgatgtcg actggcaaaa
     8761 tgttatttag gaagaaagat aaattaagaa aaatccaagt ccctgcaaaa taccagcttc
     8821 ttgtcaaaaa tccaaacact atcgccaata atatcaagcc gagatgaacc atcaagcctc
     8881 ctgaaagcat caggatgatt ctttgatcgc tttcatcctc ttttaaacca atgtattgag
     8941 caccaacatt tttcagaatg gctgttctac taagatgaaa cctgcctgac tttttggtca
     9001 aaataaaatg tcctaatcca aaagccacca gccgatagcc tgtcaagtag ccacaaaaag
     9061 catgacccag ctcatgaaga ataaagatta aatacatgct tagaagagcg aaggcataac
     9121 caaaagtaaa ggctaaaact gcggaatacc ccaactctgc aaatgcgatt gttccacaag
     9181 caaaagctag cataataaag acaacagcta gcacataaac caaataagtc ccaattttct
     9241 tcataacacc tccaaccaac tcctagtatc ttggataagg ataaaattct ccctcttcca
     9301 agccaacttt tccttcttca aagacttctt ggttccattc catgacaaat tcctctgctt
     9361 ctgggtcttc caaaaagtcc atgaggacat ctagcccaac ctcagcagta tctttaagga
     9421 aaagcacaaa ataagctaaa aattcacggg aaaatccttt tttaggcagg taaggaataa
     9481 cagtcaaata gtcttcctca ttgactgttg acttagcagg attgtagaaa aggaccgctt
     9541 cctcaaaaag aatgtcatct gatgaaacct ctccgtcttc atccaccatc tccacacctg
     9601 cagcattttg cgcttccaat agaaaactca cttctaccgc atggttgcgt ttgtcccagc
     9661 taatctcaaa gtcaaaggga aagttcttgt ccaactcttc ctctaaaaca tctaaaaatc
     9721 cgtatgttgc cattttgtcc tctttctatg cgactcttta atcgccccga ttgctcggaa
     9781 atatgctaaa atagatacta ccatcttacc acaaaattat tttatgtcct aattatacca
     9841 tattacctca tttaaaccct tggtatcagt gattttctta aaagtctgat ttcttcattt
     9901 ctcataaaaa tcaatataaa aagccctcga aagggctaat aaatctataa aatcaatagg
     9961 cgagtaacta gcacaagtgg acgtgctttt ttattgacta ttaccacgat accacgctta
    10021 atcttaggct tgaactttct tatctgcaat agcgtctgtc aaagtctgag aaaagttaag
    10081 tcccatttct cgtcccaact tatctgccca ttttggtatg gtcaaagtct ttttaatggg
    10141 ttcctgactt cctaggtatt ctgatacatc aacagatacc atagaaataa aagatttatc
    10201 aaggtcatag gttgacacga aatcttcatc atctttaaaa ggatcattat caattaaaga
    10261 caagctattg atatctgatg gctgaggtaa ctctccatca ctctctatca aatctgcaac
    10321 agttatccct agccactccg accccatagc caaagcctca gaaatcccct ctccttgtgt
    10381 agctgagtat tcaaaatctg ggaaatggac aaaataagtc gcttctgttc cgtctgtgtc
    10441 gtcataataa aataaagctg gatacgtaac taacatttca ctacctccat atcaaaaagc
    10501 agggactgaa ttttacaacc cagcttgctt tcctatccct ctttcagtgt acttattcag
    10561 ctcaccatga aggattgtga taggtctttc cccttgcttc tcgattttaa tatgggagcc
    10621 tttaccgcct ctagtcttta tccaaccatg ggccgtaaag agtttaacca tctctttttg
    10681 tgtcataggc atagcgcttt tacctcctga caacaccatt ataacacgtg ttacacgtat
    10741 tgtaaaggag tgatacttat tattctatta tacataaaag cccctagatg tggttctaag
    10801 ggaaaccaat ttattcagac ctatttttct aatgagtagt aaaaactgct tctttatcga
    10861 gcaattcatc atctgtatag tcaattgtaa aagtatctcg atctaagaca gattgaggcg
    10921 gagttgaatg aatcatagga ccactgcgta ctctatattt tttatctcca atttttacaa
    10981 actgatactc ttcgaaaatc aaattcaaac cacgtcaacg tcgccttacc gtactcaagt
    11041 acagcctgcg gctagtttcc tagtttgctc tttgattttc attgagtatg attaactctc
    11101 aagtcttcga aatcaggatt ttcaacagtt attacaagga ggcgatttac tacttcaaaa
    11161 acatcaatta ttctattttt catatttttt caacccatta ttagaatgaa cttcttggta
    11221 agcaaaatca agtttagatt taatgttttc gtacaaatct aaaatctctt ttggagtatc
    11281 ttcccggaag aaaagttttc ttttccctga aataacttga tcactaagaa tccaatgacg
    11341 aatttgtttt gtaaaaat
//
LOCUS       DAVAZV010000062        11297 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVAZV010000062 DAVAZV010000000
VERSION     DAVAZV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.062"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..728
                     /locus_tag="VQT46_001804"
                     /pseudo
     CDS             1..728
                     /locus_tag="VQT46_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(844..1647)
                     /locus_tag="VQT46_001805"
     CDS             complement(844..1647)
                     /locus_tag="VQT46_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET2371779.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNTPFQQHSKY
                     FRDALVLDNAKILQRRSEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1926..2681)
                     /locus_tag="VQT46_001806"
     CDS             complement(1926..2681)
                     /locus_tag="VQT46_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET2371780.1"
                     /translation="MSKHPHYELLNLIGYGLAKFDKLFIKEFQCSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNNRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYAEIVKM
                     LLASEGKKTGITIVEKPIVRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDARLY
                     GDGYDFQVDVQEYSYLAEVKGIRKSKGRVRLTAKEFEKVKEFQSDFILSLVTNLDDIP
                     KLVLIDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2751..5402)
                     /locus_tag="VQT46_001807"
     CDS             complement(2751..5402)
                     /locus_tag="VQT46_001807"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET2371781.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYSTTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPKFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGEIYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPNTETTDFKRYYPNSTLVTGYDIIPFWVSRMIFQGIEFTGKSPFKNAL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEEEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAEYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIFLPLVDLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(5395..5973)
                     /locus_tag="VQT46_001808"
     CDS             complement(5395..5973)
                     /locus_tag="VQT46_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET2371782.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYQLMYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5973..6443)
                     /locus_tag="VQT46_001809"
     CDS             complement(5973..6443)
                     /locus_tag="VQT46_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371783.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGYG
                     IVVKGTDKIVGSVDFNHRHEDDVLEIGYTLHPDYWGRGYVPEAARALIDLAFKDLGLH
                     KIELTCFGYNLQSQRVAEKLGFTLEARIRDRKDAQGNCCDDLRYALLKSEWEVI"
     gene            complement(6430..7008)
                     /locus_tag="VQT46_001810"
     CDS             complement(6430..7008)
                     /locus_tag="VQT46_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HET2371784.1"
                     /translation="MKQSFKTNKLYYGFPVFILGYQDQNFGYNITTCSSSYSLGDWVV
                     IGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEKLERLGVHYEISERTQ
                     TPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDEKGHFKNQLFAPTYFM
                     GDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(7291..7686)
                     /locus_tag="VQT46_001811"
     CDS             complement(7291..7686)
                     /locus_tag="VQT46_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET2371785.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLALKGIGPATIKKLKENGIKFK"
     gene            complement(7782..8036)
                     /locus_tag="VQT46_001812"
     CDS             complement(7782..8036)
                     /locus_tag="VQT46_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET2371786.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(8045..9379)
                     /locus_tag="VQT46_001813"
     CDS             complement(8045..9379)
                     /locus_tag="VQT46_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET2371787.1"
                     /translation="MTDEWIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTVKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKRLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(9379..9612)
                     /locus_tag="VQT46_001814"
     CDS             complement(9379..9612)
                     /locus_tag="VQT46_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET2371788.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLTGTPMDKIVRTLEANGYEVIGLD"
     gene            9643..9717
                     /locus_tag="VQT46_001815"
                     /pseudo
     CDS             9643..9717
                     /locus_tag="VQT46_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            9706..9831
                     /locus_tag="VQT46_001816"
     CDS             9706..9831
                     /locus_tag="VQT46_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004238277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="HET2371789.1"
                     /translation="MDRTDEVSNHTYSKVKLTWFEEIFEEYKMILLLILYHMERD"
     gene            complement(9881..10021)
                     /locus_tag="VQT46_001817"
     CDS             complement(9881..10021)
                     /locus_tag="VQT46_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371790.1"
                     /translation="MKFFWTILAILFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(10018..10200)
                     /locus_tag="VQT46_001818"
     CDS             complement(10018..10200)
                     /locus_tag="VQT46_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371791.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDHVVVGLGKLFIAD
                     KLMDTARWLIKPEERE"
     gene            complement(10202..10985)
                     /locus_tag="VQT46_001819"
                     /pseudo
     CDS             complement(10202..10985)
                     /locus_tag="VQT46_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         3327 a         2476 c         2092 g         3402 t
ORIGIN      
        1 aggaccaaga gcttaaagct gaaattcaat ccatttttat cgaacacaag ggaaattatg
       61 cttatcgctg tgttcattta gaactaagaa atcgtggtta tctggtaaat cataaaagag
      121 ttcaaggctt gatgaaagta ctcaatttac aagctaaaat gcgacagaaa cgaaaataaa
      181 ggagacgttg gtaagaaggc agagaatctc attcaaggcc aatttgaagg atctaaaaca
      241 atggaaaagt gctacacaga tgtgactgaa tttgccattc cagcaagtac tcaaaagctt
      301 tacttatcac cagttttaga tggctttaac agcgaaatta tcgcctataa tctttcaact
      361 tcacccaact tagaacaagt acaaacaatg ttggaacagg cattcacaga gaagcactac
      421 gagaatacga ttctccatag tgaccaaggc tggcaatacc gacacgattc ttatcatcgg
      481 ttcctaagag taagggaatt caagcatcta tgtcacgcaa gggaaacagc caagacaacg
      541 gtatgatgga gtccttcttt gggattctga aatcggaaat gttttacggt tatgagaagt
      601 cgtttcagtc gcttaagcaa ttggaacaag ccattataga ctatattgat tactacaaca
      661 ataaacgaat taaggtaaaa ctaaaaggac ttagccttgt gcaatacaga actaaatcct
      721 tcggataaat tatttgtcta actttttggg gtcagtacac ctaaaacttt gatgatatac
      781 gttttcttgt gagaatattt acttcatttt tgcctaaaat tcaatgttta ctcagtattt
      841 ggattatgaa aaatcgaggt ctaaatctag atacattttt tctgaagaca aatcattttg
      901 accaccgagc aagagatttt caaaaaaagc tgttaaaaac tcagaacgtc gctgtaaaat
      961 ctttgcatta tctaatacca aggcatcacg aaaatatttg gaatgttgct gaaatggtgt
     1021 attatcaata tcaaaaccaa actcacgaag atactgaatc aaaaagaccg ttactgtccg
     1081 agtgtttcct tcgcgaaatg gatgaatctg ccagattcct gaaataaaat gctggatttg
     1141 tttaaccaca tccgcctgag ttagtgtcgc atatgcaact tgtttttcct gattaaaatc
     1201 ataatctaag gtcatttgaa tcatggagta atcagagtac acaacacttt caccattcaa
     1261 aacaggttca ttctttgtga tattggtctg acgaaattgc cccaccggaa tagagggttc
     1321 aaatatatct tgaaacaact ccttatgaat agcaagtaag gtcgcaggac taaagctaaa
     1381 gcctcttcga gacaatagtt ctacaatacg tagagaaacc aagtctgcct cttccgtact
     1441 tgcatcaata gtatggtgat aagccgttgc atcctcataa acctgctcat aagtcagttc
     1501 tccccgggac tgtttctcag ccaaagattc catatacgct gatggcacta gattgtcaac
     1561 tttctgcaga ccaaaaccta tccgccataa atcacgcttc gcttcataag acaagtttgg
     1621 attgtcaatg ttgtaagttg attgcataga aatatccttt caattgtttt tcttcattac
     1681 cagtaaatca cgaaattggt tggaaactgg cttaaactat aaaaagtcct cacaataggt
     1741 tctatgatat atatatatat acttcatgta aataataaaa gagttataat cagcactact
     1801 gataaattca ataccgattt cgccatctta aaacttagtc aaacgaatac cgttgatttc
     1861 cagttcatta agtcgttgac ctgtcaagac ttctcgttcc ttcaactgga aaagttaagg
     1921 gggaactaat acaaatcctc tacgcttcta tattcaatga tttcattttt gataatattc
     1981 tttttaaact caaaatgttt taaaggatta tcgattaaca ctaactttgg aatatcatct
     2041 agatttgtga ccaaggataa aataaaatcc gattgaaact ccttgacttt ttcaaattct
     2101 tttgcagtta aacgcacacg ccccttagat tttcggatac cttttacttc ggcaaggtaa
     2161 gaatactctt ggacatctac ctgaaagtca tatccatcac cataaagacg ggcatcggtt
     2221 aactgtccac cttggaattt ttcttcttta tcaaaatgaa ggataaaata attctcagcc
     2281 tccattcccg tttcctgtag acgtttgaat ttagttcgaa ctattggttt ttcaacgatg
     2341 gttatgcctg ttttcttccc ttcactggca agtaacattt taactatttc agcataacta
     2401 tgaacatctt catttccaaa catcatatca attaaatctt tacgaaaacg ataaacttca
     2461 gctttctgcc accaaccttt tcgattattg tcaaaataag gatcaaataa atccattcta
     2521 ttttttacaa ctccagttgt ttcagcaatt cccagagaaa ccacatagcg ataaaactcc
     2581 gacttgctag agcattgaaa ttcttttata aaaagcttgt caaacttggc aagaccgtag
     2641 ccaattaaat ttaacaattc ataatgaggg tgtttggaca tcactttctc catcaataga
     2701 tattgatttc attataccaa aaaacacggc tcatcaccgt gtttctgtgt ttatttcacc
     2761 aacttcttca tctcatcaat acgtgctacg gtcgcatcat acttagcttg gtaatctgct
     2821 tgcttgtcgc gttctttttg gacaacttct ggtttagcgt tggcgacgaa gcgttcgttg
     2881 ctgagttttt tgccaaccat gtcgagttct ttctgccatt tggcaagttc tttttccaga
     2941 cgtgccaatt cttcttcgac attcaagagg tctaccagtg gcaagaagat ttcggctcct
     3001 gtgatgacgc ttgacatagc cagttcaggt gcagggatgg ttgatgcgat ttccaagtgt
     3061 tcaggatttg tgaaacgttt gatgtagttg acattgctgt taaagaaggc ttccaagtcg
     3121 ctatcgcttg tcttaacaag gatagtgata ggcttgcttg gagcaacgtt tacttccgca
     3181 cgcgcattac gaacggcacg gatcaagtct ttaaggcttt ccacaccagt gtgagcagca
     3241 aggtcttcaa aggctgggtt gacagttggg tattctgctg taacgataga tccttctgag
     3301 atttgtccaa agatttcctc tgtcacaaat ggcatgattg ggtgaaggag acgaaggatc
     3361 ttgtccaaag tgtatagtag aacagaacgt gtgatgactt tctcttcttc gttatcgcta
     3421 taaaggactt ccttggtcaa ctcaacatac cagttggcaa attcttccca gatgaagttg
     3481 taaaggatat gaccagccac accaaactcg aacttatcaa agttttcagt aacttttgca
     3541 atggtttcgt tgagattgtg gagaatccag cggtccgtca cattaccagc ctcacctgtt
     3601 gcaacttttg tgacattgtc atgcgccaca tccagcgtca aaccttcatt gttcatgagg
     3661 atatagcgag aaatgttcca aattttgtta ataaagttcc atgaagcatc cattttctcg
     3721 taagagaaac gaacgtcttg accaggagct gagccgtttg acaagaacca acgaagacta
     3781 tctgtaccat atttatcaat aacatccatt gggtcaatgc catttccaag agatttagac
     3841 atcttacgtc cttcttcatc acgaattaga ccatggataa gagcattttt aaatgggctc
     3901 tttcctgtaa attcaattcc ttggaaaatc atgcgtgata cccagaaagg aataatatca
     3961 tagcctgtta cgagtgttga atttggatag tagcgtttaa agtcagtagt ttcggtatta
     4021 ggccagccca tggttgagaa gggccagagg gcagagctga accaagtgtc aaggacatct
     4081 tcgtcctgtt tccagccatc gcccgctggg gcttcctcgc cgacatagat ttcgcctgct
     4141 tcattatacc aagcagggat ttggtgaccc caccagagct gacgggaaat cacccagtcg
     4201 tggacatttt ccatccattg caggaaggtg tcgttgaagc gcggtgggta aaattccacc
     4261 ttgtcatctg tgtcttggtt ggcaatggcg ttcttggcca attggtccat cttgacgaac
     4321 cattgagtag acaagcgtgg ctcaactacg acacctgtcc gttctgagtg accgactgaa
     4381 tggacacgtt tttcgatttt gacaagggca ccgatttctt ccaacttagc aacgactgcc
     4441 ttacgagctt caaaacgatc catgcctgaa aattcaaagg caagctcgtt catagttccg
     4501 tcgtcgttca tgacgttgac ttgtggcaag ttatgacgtt ggccaaccaa gaagtcattt
     4561 ggatcgtggg caggtgtgat tttcacgaca ccagtaccaa acttaggatc tgcgtgctca
     4621 tcaccaacga ttgggattaa tttattagca attggaagga tgacattttt accaatcaag
     4681 tccttgtagc gcgggtcttc tgggttgacc gcaaccgcaa cgtccccaaa catggtctca
     4741 ggacgagttg tagcaacttc aagggcgcgt gaaccatctt ccagcatgta attcatgtga
     4801 tagaaggcac cttcgacgtc cttgtgaata acctcgatat cagaaagggc tgtgcgagct
     4861 gctgggtccc agttgatgat aaactcacca cggtagatcc agcctttctt gtaaaggtcc
     4921 acaaagacct tacgaacagc ttttgacaaa ccttcgtcaa gagtgaaacg ctcacgagag
     4981 tagtctacag agagccccat cttgccccat tgttccttga tagtagtgga atattcgtct
     5041 ttccattccc agactttcgt caagaaagac tcacgaccaa ggtcatagcg ggaaatgccc
     5101 tcaccacgca agcgctcctc taccttagcc tgagtggcaa tccctgcgtg gtccatccca
     5161 ggaagccaaa gggtatcaaa accttgcatg cgtttttgac ggatgataat atcttgcaaa
     5221 gttgtatccc aagcgtgacc aaggtgaagt ttacctgtaa cgtttggtgg tggaataacg
     5281 attgaataag gcttagcctt ttgatcgcct gaaggcttga aaacatcagc atcaagccat
     5341 ttttggtaac gaccagcctc aacctcggct ggattgtatt tagatgaaag ttctttagac
     5401 atgtgtgtgt cctttctcta ttttgtttat tttattttga atttgcttag cagcttcttc
     5461 tgcagacaaa ttcgtattat ttattttaaa gtagtggtgc aactcattcg gttgatattg
     5521 ggaatttaat tgaagtgttt cagcggtctc taaaatttct ctttcagata cctcaatatg
     5581 tcgttttaag ggtttgtgct ttaatcgatt ctccgttcga tttcgacgta tgcactcttc
     5641 aagacttgtt tccaactcaa caaaaagaat ctcttgatga taatcatcca acaaattctg
     5701 aatttgcttt aaatacatca gttgatactg atttgaaaaa tcaattacat ctgttaaaat
     5761 tactgatcgc tgatttcttg cacttgctcc aaggaatgaa aaagtgattc cacgaacaaa
     5821 ttcccacatt tcctctgtat agtcctgata gatttctagt gcaaaatcaa tggcttgatg
     5881 gttataaaat agggtagcat ccgtcagtcg agataattct tgaccaatgg tcatttttcc
     5941 tgatgctgga gcaccaatga tgaaaagatg catcaaatca cctcccactc actcttcagc
     6001 aaggcatatc tcaaatcatc acagcagttg ccttgagcat ctttacggtc tcttatgcga
     6061 gcttcgaggg taaagccaag cttttccgcg actcgttgac tttgaaggtt atatccaaag
     6121 caagttagtt caatcttgtg aagacccaaa tctttaaagg ctaagtcaat caaggcacgc
     6181 gcagcttctg gcacataacc tcgcccccaa tagtctgggt gtaaggtata gccgatttcc
     6241 agcacatcat cttcatggcg atggttgaaa tcgacagagc caacgatctt atccgttcct
     6301 ttgacgacaa tcccgtagcc tgctggatag gcgacctctg gcaaactagc atagtcaaag
     6361 atatcctcag catccgccac agtacggact cgtaaaacga gacgttctgt ttcgatttta
     6421 tctggcagct cagttcttgc catccttctt cctcgctttt ttgatgaaac tgcccttcat
     6481 atctacacgc ttatccagat agcgataaac gcgctgatat ccatctccca tgaaataggt
     6541 tggggcaaac agttgatttt taaaatgtcc cttttcatcc aggagttctg gggcaacaag
     6601 tcgctcaaga atcttggcaa agatgtggca aataccgtct tcctcaacaa tcctatctac
     6661 ccgacaatct aaaacaagtg gacaggcgtc taaaatagga gtctgagttc gttcagaaat
     6721 ttcataatgc actcccaaac gttccaattt ctcctgatga ctgataaaac cagcctgctc
     6781 catcgcaagc atagaagttt catcagaaat attcacagta aatttttgat actgtttgat
     6841 ctgctctgcg gcattctctc tcgcaacgac tccaatcaca acccaatctc ctagactata
     6901 cgaggaacta caggtcgtga tgttatagcc aaaattctga tcttgatatc ctaaaataaa
     6961 aacaggaaaa ccataatata gtttattagt tttaaatgat tgttttataa caacctcctt
     7021 tgactaagac acaaaagaaa agccctgcca tctacatgac agggacgaat gtatttatcc
     7081 gcggtaccac ccaatttcgg gccaagcccg catctttagt ctttaaaata aaaagacaga
     7141 aatatttcat tttttcagtc attagcaacc agttttgaca catttgtgga cttctcagcg
     7201 ccgccacttt ctgtaaaatg tgggattcaa aacacctcta atagctctat tgtagcaagt
     7261 ttttctcgga aatgcaaggc tcaagaaaaa ttacttgaac ttgatgccat tttctttcaa
     7321 tttcttgatg gtagctgggc cgattccttt caaggcaagg agttcttttt cagtccagtt
     7381 tttgaaatct gaagcagact tgattccttc atcatagaaa gtcttggcac gatcaagtgg
     7441 aagtccaccc aagtttgctg caaaatcttc tacagaatta gctacttttt gagcttgctc
     7501 tttggtagct tctactgctt gttcaacttt tttagaaaca gccttaccag ctgcgcttgc
     7561 tgactgttct gcacgcttca cgactttttt tgtctcatct acaaccttag tcacagtact
     7621 tgaaaaggca cctgcgcgac ggaggccatt tcgtaattgt tttttacgat tgagtttctt
     7681 tgacatgata aaatcctttc aataaaaaat ccctgctctg acaaggattt aacataaaca
     7741 ttctatcaag attttagtga aaaatcaaga atctttctcg tttaataatt tcgctcacca
     7801 aacaagcctt ctggcaaatc atggaatccc ttgcctactt tgaagttttc aaacttacca
     7861 agcaagaact gataagcatc caagcgactc tcgtagcgaa tcatggcatc tttggcacgc
     7921 tcgtcctggt cttcttcgta aactttttga ctttccttgt gcgccatgtc gttaatcatg
     7981 atttgggtat tgacccaagc ttcaaattcc ttcataaatt cttgttcgta actcattttt
     8041 ctccttattc taatccacga aaatagtccg tatcaatctc acggtagggc tggatatcct
     8101 gaacatactc caacactcct tggaattctc cgtcttcatc gtgtactgca gcataggtga
     8161 tgtggacaaa cttacctcgc gactcagact tgaaccacat ttcatacttg tctttgcttc
     8221 cctcacgaag cctcttcatg atagttttga ccttgtccaa gtacttaggc ggatggcaga
     8281 gttcgacatt gcgcccgact tgagacggcg tccgtttgaa aatcatctca tcagctggcg
     8341 tattgtcatt gtaatactgg aaaatatctt ctttattgac aaaggtaatc tccataggga
     8401 gatgattgag gatgagattg gcctgctcga ctgaaagata gccattacca aaagcctgtt
     8461 gactatggcg gtccagcaca gcttcctttt ccttaggggt aaaggtaatg gtaaaatggc
     8521 cttctggcgt atctatgact tgttgaactt gaccttctgc cgtatctagc tgtacaggct
     8581 cctctgcaat cttttcctca ataaagctct gtcgttctgg cacccatttc tctgacggac
     8641 ggatgatggc atagccatag gcatcgctct cctccgcaat ctgaagccag tcatcctgag
     8701 taaaagactc aaggagaatc atgaggagga tggactcttc cttgaaaatc atactttcaa
     8761 actctgtcgc aaaagcttca aaagcttcct ttacactgct aattgacact tctggtagtg
     8821 acttgactgt cgttagagct gtttgaaaga gttccctaat ctgatcatcc actccccaca
     8881 taactttggg aggtgaatcg tgtccatagc gctccatgat aggaaagaag agttcttcct
     8941 tacgttggta atggatgtca aattgcccca caagccccat ctgacgcacc aagcccttgc
     9001 gcatctccgc aagcatttcc tcgtcttcca tcaactcata ggtatctaac aatctacgaa
     9061 tgcgaatcaa agctgcacgg agggccaaat tttcttcctt aaagacacga actgggtgcc
     9121 cagggtgttc ggtatctaaa acttcgacac ctttgatagc atttttaaaa agattggcat
     9181 ggacatcaca gagttccata acatcttcaa aagtgacgcc cgaatccgag ttcatcagct
     9241 cgtgctccat aagggaaatc tcgatggctg acacgcccgt aaaggtcgca tcaaagcgat
     9301 cttgaaccga ctcaggagag gcgccattgt gcaattctaa caaaatatcc cgtaggatat
     9361 gaatccattc atctgtcatt agtctaatcc aatcacttcg tagccattcg cttccagtgt
     9421 gcgtacaatc ttgtccatag gagttcctgt tagcttagaa ccctgtttaa gtgatacttt
     9481 acgaccaact gtattgcgca ttaagggatt ggcaaggggt ttaaaaccca actccactag
     9541 aatttccaag acttctggat gcttgtccac cacttctgca acaggaattg acacatcgat
     9601 gatattgtcc atgacgacct ccattgtatg ttctaatact caatgaaaat caaagagcaa
     9661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtgga tagaactgac
     9721 gaagtcagta accataccta cagcaaggtg aagctgacgt ggtttgaaga gattttcgaa
     9781 gagtataaaa tgattttact gcttatatta taccatatgg agagagatta aaaaactagc
     9841 agtggagttc ctgctagttt tctgcgactt ggattaccat ctagataagt ttaaagaacc
     9901 aatccaatat cttgtaaaac agcaattgaa ctgcaaaaga aatgatcatc caaaagaatt
     9961 tcacaatccc aataatcggt ttgataaaaa gaatagcaag aattgtccag aaaaatttca
    10021 ttctctctcc tctggcttaa tgagccaccg agccgtatcc attagcttat ctgcaataaa
    10081 gagttttccc agaccaacaa cgacatggtc atctttcttt atcgttttca tcacttttac
    10141 accttgcacg gtcaaaaagt aattaccata aattttagca aaagctttga taggattcat
    10201 attattctcc tttgatgatt tcagcctctt ttcggattgt ttcaacatct tcttgatatt
    10261 gaacttcact atagttgact agcttggata attctttctg caagctttcc cccattggtt
    10321 tcatagttgc aaaggttaaa ccacctgaaa tgataccacc caagatagga ataaatttcc
    10381 ccattccttt ggccaaccct cccttggtaa gattcacacc aaatattttt aagacttttt
    10441 tcaaaatagg gtaccaaagc gtctttgtta aagctttatt aggcactgtt ttcattacct
    10501 gtttggcaat tgttatacca ccagcacgta gcaaacaaag cagcggttcc attcacccct
    10561 aacattacgc ctagataaag caagagggta ttttgagcat cttcactcaa ctcctcacgt
    10621 gaagcccaaa gatcctcata accataaata taacctaatt cttgggccaa tttcagagag
    10681 aaaccataaa attgagccac ataagctgga atggtaattg ccatagcaag ccctccaggt
    10741 aatcctgcca aaacagaagt cccactcgct aataaaacat tatccctaat acaggcatta
    10801 gccactcgat ctaagatttc ttgagataag agagacgttg gaccttgttc caataaggta
    10861 ggaatgtcct gtggacccaa ttctttggaa aacttatcca ctaaaaattt cgaacgatca
    10921 accttaacaa ctggtagttt taccacttgt tgtaatactt gcatagctaa gtcttgttca
    10981 gccatataca aactccttat ttcttttttg caccttatca tattatattt cctacaaaaa
    11041 aagcattttc taattagata acattaaaaa atacagaacc ccttttttat agtaaaataa
    11101 aacaagaaca ggacaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag
    11161 tagaggcgta ctattctagt ttcaatatat tttaaaagaa tatttttcca tttcaaattc
    11221 aacctatttt cctccaccaa aaaagggctc tataatattt gtagtgggta aattccctat
    11281 ggatattatg gagccta
//
LOCUS       DAVAZV010000063        11272 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVAZV010000063 DAVAZV010000000
VERSION     DAVAZV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.063"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..947)
                     /locus_tag="VQT46_001820"
     CDS             complement(<1..947)
                     /locus_tag="VQT46_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2371792.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQVIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFILVTFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTI"
     gene            complement(1027..1890)
                     /locus_tag="VQT46_001821"
     CDS             complement(1027..1890)
                     /locus_tag="VQT46_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET2371793.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTSLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGFALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(1893..3794)
                     /locus_tag="VQT46_001822"
     CDS             complement(1893..3794)
                     /locus_tag="VQT46_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2371794.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENAAV
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINCVAT
                     HVLELSENGSTLYLGDYDYYVEKKATAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSDQV"
     gene            complement(4222..4497)
                     /locus_tag="VQT46_001823"
     CDS             complement(4222..4497)
                     /locus_tag="VQT46_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET2371795.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(4603..5442)
                     /locus_tag="VQT46_001824"
     CDS             complement(4603..5442)
                     /locus_tag="VQT46_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2371796.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVIVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILSHVEEVKNHTELYIGV
                     STLENLVKGGRIGRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            5584..6432
                     /locus_tag="VQT46_001825"
     CDS             5584..6432
                     /locus_tag="VQT46_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET2371797.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(6525..7442)
                     /locus_tag="VQT46_001826"
     CDS             complement(6525..7442)
                     /locus_tag="VQT46_001826"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET2371798.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            7879..8084
                     /locus_tag="VQT46_001827"
                     /pseudo
     CDS             7879..8084
                     /locus_tag="VQT46_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQT46_001828"
     CDS             complement(8395..8688)
                     /gene="rpmA"
                     /locus_tag="VQT46_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET2371799.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(8705..9049)
                     /locus_tag="VQT46_001829"
     CDS             complement(8705..9049)
                     /locus_tag="VQT46_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET2371800.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQT46_001830"
     CDS             complement(9065..9379)
                     /gene="rplU"
                     /locus_tag="VQT46_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET2371801.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(9415..9502)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(9597..10196)
                     /locus_tag="VQT46_001831"
     CDS             complement(9597..10196)
                     /locus_tag="VQT46_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET2371802.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLL
                     SSFVLGDVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            10666..10965
                     /locus_tag="VQT46_001832"
     CDS             10666..10965
                     /locus_tag="VQT46_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET2371803.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         3573 a         2333 c         1870 g         3496 t
ORIGIN      
        1 aaaatcgtca taaacaattc acaaactaaa tttccagaaa aggaaagaaa agttggaagt
       61 ggtaatccca tcataaaaac tccgacacct gtcaaagcca gtaaaatcaa aagattataa
      121 atattagctt taattttact agctagaaga gccccaatga tggaaccaat agcccccata
      181 gttaaaatac ttgcataggc tccttctgac ccgtaaagct gattcgaaaa gggaagtaga
      241 aattcaaaag ctgcaaaaaa gaaattaacg ctggaagcta ccagcaaaag gaagaaaatt
      301 tcttgctgat gccagatata gtgtaaccca tccttgatat ctacaaaaat atctctccca
      361 gtaaaagcct ttttctcttg aacttttgct tcctcttttg gaaggaaagt cactagaata
      421 aaagcaatga aaaaagtcag cgagtctagc agtagcgtca tatggagact tgcaaactgt
      481 aaaacaagga aggaaagaac aggagagcta acacctacaa cctgcaaaac cagctctaag
      541 cgagaattat agatcacaat ctcatctttc tccaccactt cagttatgat agctttattg
      601 gctgtgcgag aaaaggcaaa agcaataacc tgcacaatgt tagcaacaat caaagcgcca
      661 atcatccagc tatcattcct tatgaaagaa atagccagac aaagaatccc acaaacaaga
      721 tctgccgtca ttaaaatctt acgacgagaa aaacggtctg aaataactcc gccaaaggga
      781 ttgacgagaa tagatgtgac gagctcagaa atctgataca ttcctaaaac tgtctgtcct
      841 atagtcccca tagaagccaa ccagacacta tttccataat catagagcat atttcccatt
      901 ttattgatag ccccacggct aatcaactgc actgcatagc gattcatatt aaagctcctc
      961 tcaaattttg aaactattgt atcaaaaccg aaaggagctt tttatttttt cccttatttg
     1021 ggaaaattaa cttttgacaa atttttcgta gtgttcctga taataggcta cttgctctgg
     1081 aagacctaac acatcaaaaa tatgcatggc ctcttgcatc tgcttacagc cttctttaca
     1141 ctgtcctttt tgatataagg caaaaccttt taaataatgg aaaacattac gctcataaag
     1201 cttaatacct ttgtcaataa tcttctctgt ataagcctca aaatagttgg cattataaaa
     1261 agaagaatgc tctaaacaat gctggtaaca attgagggcc aaaatcaaca ctaatctctt
     1321 atggcgacta atctcttggt aaaattcctc cctctccata acttctctac caatccgagt
     1381 gacatagtct acatcgtaga aactatagag gttaccgaaa agaatcaact catacatggt
     1441 ccattcttct gttttgaaga gataatctgc taccttatcc aaatcatcct gcttcatatc
     1501 ataactcgca tctctttgac aaatcagacc ttgtagcaaa atccagttca gctcaaaata
     1561 aagggaagtc gtcgaactct tagacttttc aagttgttct ctttgaagct tttgaaaacc
     1621 tgcaatatcg tttgaatagt aaagtgggat aatctgtgcc atcatagaca catgttcatg
     1681 attatgaaaa ttccttgcct tatccatgaa attttcgatt gttacatgaa tgttatccaa
     1741 aatctcaaag aaacgggaga ctgccaggtc agactcccca agctcaaagc gagataactg
     1801 agaggtagag caggattcgc ctgctgcttc ctttaaagaa taatttccac ttgttcgaaa
     1861 ttcacgaaat acttttccaa gatgttccat ctttacacct gatctgataa ttcttcccac
     1921 tcaagcatag cttcttcctg acgatggctg attttatcca gctcagcctg taattccatg
     1981 agtttgtcgg catcgtttgt ttccaacatt tgttcagaaa tggcttggct ttgactttct
     2041 agctcttcaa tttcagcttc tagactttcg atttgtcgca tgagtttgcg aacttctttt
     2101 tgactttctt tctgggcctg atagtcattg actggacttg cttcctttgc ttgattgcta
     2161 gttgaagctt cctcagtctg actcatttct gctgttgctt tcttctcaac atagtagtcg
     2221 taatctccaa ggtagagagt tgaaccattc tcagacaatt ccaaaacatg agttgccaca
     2281 caattgataa agtaacgatc atgactgaca aaaagcaagg taccatcaaa gtcaatcaag
     2341 gcattttcta gcacttcctt actatcaata tccaagtggt tggtcggctc atccagaatc
     2401 aaaaagttat tgttttccat agacaattta gctaaaagca aacgagcttt ttcgccacca
     2461 gatagcatgc cgactgattt tttaacatca tctcctgaga aaaggaaggc tccaagacgg
     2521 ttgcggattt caacttctgg tgtcaatttg aaatcattcc agagttcatc cagcaccgta
     2581 ttacttggtg tcagcttgct ttgggtttgg tcatagtaac caacctcaac attagcgcca
     2641 aagcgctttt ctcccttgat aaacggaatt tgatccacga ttgatttgat aaaggttgat
     2701 tttccgatac cattgggacc aacgatagca acagcattca tcttacgaag gtctaggtta
     2761 atcggttgtg acaggacttc cccatcatag ccaacagccg cattttcaac agtcaaaaca
     2821 acattgcccg acgttttttc agactggaag gtcatgttgg ctgctttctt gccagcttcc
     2881 ggcttgtcca aacgctccat tttttctagt tgtttacggc gagattgagc acgtttggtc
     2941 gttgaagcac gaactagatt gcgattgaca aagtcttcca gagcagcgat ttccttctgt
     3001 tgcttttcat agttttttgc ctcagtagct agcttttgct ccttcaactc gacaaaacga
     3061 gagtaattcc ccacatagcg atccaaggaa tgcttggtca aatctagcgt aattgtcgca
     3121 accttgtcca agaaataacg gtcgtggctg acgataatga gggcaccgct atagtttacc
     3181 aagtaattct ctagccagga gatggtttca atatccaagt ggttagttgg ctcgtccaag
     3241 accaagagat tgggcttttc aaggagcatt ttagctagag ccaaacgagt attttgacca
     3301 cctgaaagtt cagctatttt catctgccac atagactcgt caaacttgaa tccattcaaa
     3361 atcgctcgaa tatcagcttc ataggtaaag ccacctgctt ggcgaaaatt ctcagataag
     3421 cggtcataat ctgacatcag tttatccaaa tcctcaccag acttttcacc catctccagc
     3481 tccatctgac gcagttgtct ctccgtccga cgcaaatcat taaagacatg aagcatttca
     3541 tcgtagatgg tattttcaga ctcaaaacgg ctatcttggg ctaggtaaga cagagaaata
     3601 tcttttttct tattgatttc tccgctagtt ggctcctctt ctccaactaa aatcttcaaa
     3661 agagtagact tacctgcacc atttttccca acaagagcaa tccgatctcg ttcatcaacc
     3721 tgcaggttga tattatcgaa aagaacctct cctgcaaaag aacgttcaat tttattagct
     3781 tgtaaaataa tcataagagt agtatagcat gtttccctaa ggcattcaag ataatcgtaa
     3841 gtcttttagt acaactttta taacataaaa taaactaaat tatgtatatt ttatattaga
     3901 ttccttcact atcttgttgg attttctaac cagctaatct tgtttcaaat agttatcgca
     3961 caagcctatt atttaattct tttcattatt tacgtacgcg tatagcagat tgaaataaga
     4021 tgagaacaaa tcgattggga aagtaaaatt aatttctata aatgttttag caattgtttc
     4081 gtactatttt agattcagtc tactatgtac aatattttcg gaacattcaa ctttttaact
     4141 ctatttatta ctagatttca taattaaaaa gcctactgac caagctagaa agcttgatac
     4201 aataggcttt ttaaagactg attatttaac agcgtcttta agagctttac cagctttgaa
     4261 tgctggtact ttagaagctg caattgtcat ttctttacca gtttgtgggt tgcgaccttt
     4321 acgttctgca cgctcacgaa cttcaaagtt accaaaaccg atcaattgaa ctttttcacc
     4381 agctgcaaga tagtcagcta ctgctgcaaa tacagcttca actgctgctg ctgagtcttt
     4441 cttagtcaat tctgtagctt ctgctacttt agcgatcaaa tcttgtttgt ttgccatgtt
     4501 aatgattcct ccagataatt tctaattaac aaatataatc atatcctaaa atccctttta
     4561 ggtcaagtta aaaacgctat ttcttccaat tttatttatt ttttaggagt ggtaacgtat
     4621 caaaatagcc caagcgttct cacccgtgtg agtttgaata atggaacccg tttccaaaac
     4681 agaaattggc ttttcaacat aagcttgtaa gctttctttc atctcttttg cccaatcatc
     4741 actaccagaa tatgaaattc caatctctgc tacagcacgt tcagaaagcg atgttatcaa
     4801 ctcatctaac cattttttaa atgttttagt tccacgacct ttaaccattg gctgcaattc
     4861 atggtctttc atttgcatga caacacggat attgagaagg gagctcaaca agccagttac
     4921 acggccaatt cgtccacctt tgacaagatt ttccaaagtt gaaacaccaa tataaagctc
     4981 tgtatggttt ttaacctctt ctacatgaga taaaattgcc tccatatctt taccttcttg
     5041 agctaacttc gcagcctcaa caacttggaa tttcagggct tggtcagtga aggaactatc
     5101 aacaacaatc acatctgcag tagataggct agcaccttgg cgtgctgctt ctaccgtacc
     5161 cgaaagagca tgggacatat gaatagcaag aatctggcca ccatctttgc ataggtcttc
     5221 aaaaatctca gcaaagacac ctacaggtgg ctgacttgtt ttcggaagat tcttactttc
     5281 ttgcatcaac tgaagaaatt taccttcttc tttcaaatcc gcatcagaat aaacaacatt
     5341 atcaatcatt acagataatg gaacaattgt aatatctaat tgctttacta gttcaggttc
     5401 aatagtaaca gatgaatcgg ttacaatctt aatttttgtc atagtatcaa tctttctatt
     5461 ttaggattca gattggtttc cttacttcta attatatcaa aaaaaagatt aaaaatccta
     5521 atggagtcaa tcaaattttc cgtaaaattt gatataatca acttataaga aaagaggtgt
     5581 cctatgatta aaaaaattta ccccattttt accattttac taggtgctgc tatttatgct
     5641 tttggactga cttattttgt agttccccat catctctttg aaggaggggc gacaggtatt
     5701 accctcatca cattttatct ttttaaaatc cctgtttccc tcatgaacct gctgattaat
     5761 attccccttt tcatcctagc ttggaagatc tttggagcca aatccctcta ttctagttta
     5821 ctaggaacct tagctttgtc cggctggtta gctttttttg agcatattcc ccttcatatt
     5881 gatcttcaag gtgatttact aataacagcc cttatagcgg gaatcctatt gggaattggc
     5941 cttggaatta tttttaatgc tggaggtaca actggcggaa ctgatattct agctcgtatt
     6001 ctcaacaaat acactcatat atccatagga aaactgctct ttatcttaga tttttgtatt
     6061 ctcatgttga ttctcctaat cttcaaggat ttgagattgg tttcctacac gcttttgttt
     6121 gattttattg tttctcgtgt tattgatttg attggtgaag gaggatatgc cggcaaaggc
     6181 tttatgatta tcacaaaacg tcctgaccaa cttgctaagg cgattaatga tgacctcgga
     6241 agaggtgtta cttttatttc tggtcaaggc tactatagta aagaaaattt gaaaatcatc
     6301 tactgtattg tcggaagaaa tgaaattgtg aaaacgaagg aaatgattca tcgaatcgat
     6361 cctcaagcct ttataactat tacagaagcc catgaaatcc taggagaagg cttcaccttt
     6421 gaaaaagaat aaaaagaggt aatgtcgtga cctcaaaagt tagactaaat catctatctt
     6481 ttgggttaca gacaacctct tttttgtttt atttactcaa gctcttaaga ccaattccga
     6541 gttacttctt catcagcctt taactgatcc actaattggt caactgagtc aaatttggtc
     6601 atatcacgaa tgcgatcaag ccaataaacc atgacggttt ccccataaat atcttgatta
     6661 aaatcaaaaa tattgacttc aaaacgtgct tcttctccat caaaggtcac atttttcccg
     6721 acactagcca tagcacgata cttctgtctt tgaatctcaa catcaacgac ataaacgcca
     6781 tctgctggca tataagtacg gtctaaaagc actaaattcg ctgtcggata accaattgta
     6841 cgaccacgag cattaccatg aaccaccata cctcttgatg gaagcggtgc ccccaaaagt
     6901 tttcctgctt ctttcacatt tccatctaaa atagcttgac ggatacgagt tgaactaatc
     6961 tttcctttct catcttctac aggtggaaca atgataactt ctccatcaaa gtaatccttt
     7021 aaatcttctg ctgttttttt gtcagaacca aatgtataat caaaacctgc aacaataatt
     7081 ttggcattca tagccttgat ataagttgca aagaattctt gtgcagtgag actagcgaat
     7141 tgactactaa aatcaaggag atataattct tctacacctt cgcgctttaa ttttctttca
     7201 cgttcagcag ggttcaaaat atgcaaaaac aaatccggat gataaggctc taaagcgatc
     7261 tttggagatt cattaaaggt cataacgacg ataggtaata aatcctttct cgcagccttg
     7321 ttggcaacac gaaataattc ttgatgcccc ttatgtatgc catcaaaata gccgagaaca
     7381 acgactgaat cagatggtgt gccaatatct ttttggtttt ttataggaat agtaataatc
     7441 ataaaataat tatatcatag cgatagctat ttctggaaca gaaaatctga aatgttgttt
     7501 ttttcacatg aagtgtacct gttttcaaaa agcactttat tctatcgttg cttaactatg
     7561 aactttgcaa tattcttctc aaaaacttgt aggacatctt caaaattttg caaggagtga
     7621 ttagacttgt tcggtaacca taaagtgtca tactatgtta tgtatgaaaa agcaatgcaa
     7681 ctaactcctg agaactttaa attactaatt ggtgccgaaa aggtagaatt tagaatcgag
     7741 gtacacctat ggctgtaaaa tttacaaaat gagacaactt gggcaagatg tttgaagaat
     7801 ttcctaaact ccctgatttg aagcaagtca ctttccctga tgacaaagaa aaaagccaaa
     7861 acagcaaaga aaaactagat gactgctttc caacaactcc catctagtgt gcttcagact
     7921 gggctatttt tctctccatc tgttagcttg gattctcaga ccgtttcagc taaagaatat
     7981 cttttccctt atcagaagga acggctcaaa ccattcagac aagtgaaggg acgacaagcc
     8041 aatatttgaa accagatagc agttcttata gtcaattgaa ataaaatctg aagaaatcga
     8101 gtaggaaact catatcaatt tttaacagtg ttctattcca gattcatact caatgaaaat
     8161 taaagtgcaa actaggaagt tagccgcagg ctgtacttga gtacggcaag gtgaaactga
     8221 cgtggtttga atttgatttt cgaagagtat caatccacta tacatattaa aaagtatgga
     8281 tatcaaaaca aaaaaacagg ctctccgaaa actcggaaag ccttatttta agctgtttct
     8341 agcttcctca cctttacatt tcaaggttcg ggataaaagg ttcaatggac ctttttattt
     8401 agcgattggg taaacagaaa cttgtttttt atcgcgtcct ttacgttcaa agcgtactac
     8461 gccttcaact ttagcgaaca aagtatcgtc tccaccacga ccaacgttta cacctggata
     8521 gatgtgtgta ccacgttgac ggtaaaggat tgatccacct gttacagttt gtccgtcagc
     8581 tgctttagct ccaagacgtt ttgcttgtga atcacgtccg tttgatgtag aacctccacc
     8641 ttttttgtgg gcgaaaagtt gcaagttgtt aagagtcatt tttaacataa tgttttcctc
     8701 cgtgttagtt ttctgtgata actctggttt ggacgaactc agaatagttc tccgataagt
     8761 ttgccatacc taagaaaaat gattcaaaga ataactgggt catttctctc tggtgtgaag
     8821 gaagatcttt tggtatttca accatcagat agccaccttc atcttcgttt aattctagga
     8881 ttggttcata gcctgcaaat ttctcaatag aattgataaa gttaatggca agcgtagaaa
     8941 ccgatgcaca cacgacatct aagccgtatt cgccactctc ggcgtgtcca gtaatttccg
     9001 cacccctcag ctcgccatct tcggctctct caaagactgc ttgtatcatg tgttctcctt
     9061 aaaattaagc gttaattgcg ttgatgacaa cttttgtata tggttgacgg tgaccttgtt
     9121 tacggtggct acctttttta ggtttgtact tgtaagtaac aactttcttt tgttttcctt
     9181 gtttttcaac agttccaact acagtagctc cagcaacaag tggagttccg acaacagtgt
     9241 tttcaccacc aacaagaaca acttcgttaa aagtaacttc ttgaccagct tcaacgttca
     9301 atttttcaat gtaaactgct tgaccaactt caactttaac ttgttttccg ccagttttga
     9361 taattgcgta tgtgctcatt atgcacctcc tatgattttt atgggtttcc ccgatttttt
     9421 gtgaagactc gcctagcatc gtgggacaaa ccacttaaac ttgaataatc aagcaacgat
     9481 gttcgtgcgg ttgcacagga tcgtgcatag tcaactcttc aagtatagca tatctcctat
     9541 tttcttacaa gtaataacac ctaaaatcaa gctttttctt ttactttttt ctgccactag
     9601 gcaaaaagca tactgagata aaaaatgctc atcataatag gaacaccaag aatggtcttt
     9661 tcatgataga aaatcgtcaa ataggctgaa aagacatcgc caaggacaaa actactaagc
     9721 aggctaacaa atatgaaccc ttcacgcaaa aaaggagtgt gcttagttcg gaaataatct
     9781 ccaaaagcta gcattgttcg tttgatattc cctgtcataa aggcattatt gtaggcaata
     9841 cccgaaacct caccaaaagc agttgtcacc agtcccatac agaaggccaa gggctgcact
     9901 agatagatat tatctacagt ttgtggcaca aaaccaataa ttattgatag gattgctaaa
     9961 ggaatcaagg acagaatagg ttttttcaca attctcaatt tttccttata aatcgttaat
    10021 aaaaagactc ccattataaa cgttattaag gttaaaagct tatccctaac atccgaaaca
    10081 ttattttgta ttagctctac cgaaagaaag acaacatttc cagcttgtcc agctacaagg
    10141 gtattccctc gaacaataaa agtgtaagca tccacatatc cagcacaaaa tgtcaaaaaa
    10201 gtgctaacct tttagactga cgtgatattt ttcttatagg taataacctc attttccctc
    10261 ccattgtatt ttctcttaga aatattgtac catttctttc taaaaaatcg tagactacca
    10321 tttagatttt actattagca taaaaataat aatagacaac tatttatcca aaaatagata
    10381 gaggtaacat gtttgcaaac aaagcatacg aacctttagt aaaatcattt ccatgaaact
    10441 agaatagagc ccctcttagc aaaaatcatt attttaattt atttctaatc actccttgac
    10501 ataaataact ctcaccaata aaagactatg tcttaaaaaa atggtataat aaaatcaata
    10561 cctgggcttg atggctatgc tactaataac aattaggaga gaaaatcagg cacttgttaa
    10621 caacaaggat tatccccttg agatgaaagg aactttagaa atcttatgat gaacatgcaa
    10681 aacatgatgc gtcaagcaca aaaacttcaa aaacaaatgg aacaaagcca agctgaactt
    10741 gctgctatgc aatttgttgg caaatctgct caagatcttg tccaagcgac cttaactggc
    10801 gataagaaag ttgtcagcat tgatttcaat ccagctgtcg ttgacccaga ggaccttgag
    10861 actctttctg atatgaccgt tcaagccatc aactctgctc ttgaacaaat cgatgaaact
    10921 actaagaaaa aactgggtgc tttcgctggg aaattgccat tctaaaaaca aggagctaga
    10981 acaatacttg tcgataacaa aggctaagaa aggtgcaaaa attataaaaa acgcatagta
    11041 tcaagcaacc taaaactttg ggctctataa tatttgtagt gggtaaatcc actatagata
    11101 ttatggagcc tattttattg tagaaaaaaa tcccataaga tctataatga aaagcgacca
    11161 aacaactcat tagaaagatt catatgggac aattacattt tatcacaaaa ttactagaca
    11221 ttaaagaccc taatatccag attttagaca tcatcaataa ggatacacac aa
//
LOCUS       DAVAZV010000064        10989 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVAZV010000064 DAVAZV010000000
VERSION     DAVAZV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10989
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.064"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            136..2316
                     /locus_tag="VQT46_001833"
     CDS             136..2316
                     /locus_tag="VQT46_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET2371804.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2368..3183
                     /locus_tag="VQT46_001834"
     CDS             2368..3183
                     /locus_tag="VQT46_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET2371805.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETLVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAMLNWK"
     gene            3323..4666
                     /locus_tag="VQT46_001835"
     CDS             3323..4666
                     /locus_tag="VQT46_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2371806.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLEIVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            5043..6233
                     /locus_tag="VQT46_001836"
     CDS             5043..6233
                     /locus_tag="VQT46_001836"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET2371807.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            6786..7721
                     /locus_tag="VQT46_001837"
     CDS             6786..7721
                     /locus_tag="VQT46_001837"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET2371808.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            7755..8792
                     /locus_tag="VQT46_001838"
     CDS             7755..8792
                     /locus_tag="VQT46_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET2371809.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNSSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            8965..9570
                     /locus_tag="VQT46_001839"
     CDS             8965..9570
                     /locus_tag="VQT46_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET2371810.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            9726..10256
                     /locus_tag="VQT46_001840"
     CDS             9726..10256
                     /locus_tag="VQT46_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET2371811.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQT46_001841"
     CDS             10277..>10989
                     /gene="rlmN"
                     /locus_tag="VQT46_001841"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET2371812.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFP"
BASE COUNT         3341 a         2017 c         2395 g         3236 t
ORIGIN      
        1 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
       61 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
      121 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
      181 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
      241 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
      301 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
      361 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
      421 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
      481 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
      541 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
      601 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
      661 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
      721 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
      781 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
      841 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
      901 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
      961 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
     1021 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
     1081 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
     1141 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
     1201 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
     1261 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
     1321 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
     1381 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
     1441 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
     1501 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
     1561 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
     1621 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
     1681 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
     1741 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
     1801 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
     1861 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
     1921 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
     1981 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
     2041 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
     2101 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
     2161 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
     2221 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
     2281 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
     2341 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
     2401 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
     2461 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
     2521 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
     2581 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
     2641 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
     2701 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
     2761 gccctagctg aaactttagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
     2821 tggtgggata aaggtttcca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
     2881 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
     2941 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
     3001 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
     3061 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
     3121 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatgtt aaactggaaa
     3181 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
     3241 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
     3301 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
     3361 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagata agttgattcc
     3421 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
     3481 tactttcttg ttaccgattt tccagcaatt agatgaagct agcgatagtg tacaagcagt
     3541 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
     3601 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
     3661 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
     3721 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
     3781 tgaagcagat atgaccttgg atatgggatt cttggaaatt gttgataaga ttgctggcag
     3841 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
     3901 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacta aaacggttat
     3961 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
     4021 ttaccaattg actcagttga tgcagccgta tttggcaatg atttttgtta acactaaaac
     4081 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
     4141 tggagatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
     4201 tgagtatatt gtcgcaacag atttagcagc gcgtgggatt gacattgaag gtgtcagcca
     4261 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
     4321 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
     4381 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagatgggga
     4441 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
     4501 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
     4561 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa actaagcgtg ctgaaaatcg
     4621 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
     4681 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
     4741 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
     4801 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
     4861 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
     4921 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
     4981 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
     5041 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
     5101 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
     5161 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
     5221 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
     5281 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
     5341 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
     5401 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
     5461 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
     5521 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
     5581 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
     5641 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
     5701 tcaaagaagt tattccatct tcttatcttg atgataagac aaaattcttt atcaatccga
     5761 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
     5821 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
     5881 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
     5941 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
     6001 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
     6061 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
     6121 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
     6181 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
     6241 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
     6301 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
     6361 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
     6421 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
     6481 taatcatggg gatatttcaa tccaaagttt tattcgttat cacttgacta ttgcaaggtt
     6541 ttctagagca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
     6601 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
     6661 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
     6721 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
     6781 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
     6841 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
     6901 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
     6961 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
     7021 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
     7081 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
     7141 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
     7201 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
     7261 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gaccaagcgg
     7321 cagctatttt caacaaatat ccgctcaagt ttgtcaactg tgttaactct atcggaaacg
     7381 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
     7441 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
     7501 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
     7561 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
     7621 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
     7681 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatcg aaaaatctga
     7741 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
     7801 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaag
     7861 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
     7921 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
     7981 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
     8041 atgatgagct taagtcattt gaggaatacc ttgacaattc ttctccaaca accaagttga
     8101 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
     8161 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
     8221 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
     8281 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
     8341 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
     8401 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
     8461 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
     8521 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
     8581 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
     8641 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
     8701 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
     8761 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
     8821 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
     8881 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
     8941 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
     9001 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
     9061 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
     9121 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
     9181 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
     9241 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
     9301 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
     9361 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
     9421 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
     9481 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
     9541 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
     9601 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
     9661 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
     9721 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
     9781 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
     9841 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
     9901 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
     9961 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    10021 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    10081 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    10141 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    10201 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    10261 agaataagga gaagaaatga aaccctcaat tcatagtttg gcacatcaaa ccatgcagga
    10321 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    10381 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    10441 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    10501 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    10561 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    10621 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    10681 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    10741 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    10801 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    10861 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    10921 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    10981 tgcctttcc
//
LOCUS       DAVAZV010000065        10659 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVAZV010000065 DAVAZV010000000
VERSION     DAVAZV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.065"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            588..986
                     /locus_tag="VQT46_001842"
     CDS             588..986
                     /locus_tag="VQT46_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2371813.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEVGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKKQTVFLILQQ"
     gene            1024..1713
                     /locus_tag="VQT46_001843"
     CDS             1024..1713
                     /locus_tag="VQT46_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2371814.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQLTLIVQNYWQFSSQIGNFV
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            1755..2003
                     /locus_tag="VQT46_001844"
     CDS             1755..2003
                     /locus_tag="VQT46_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371815.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLKWFVLERLELKDDA"
     gene            2033..2644
                     /locus_tag="VQT46_001845"
     CDS             2033..2644
                     /locus_tag="VQT46_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2371816.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            2805..3599
                     /locus_tag="VQT46_001846"
     CDS             2805..3599
                     /locus_tag="VQT46_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET2371817.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            3596..4231
                     /gene="trmB"
                     /locus_tag="VQT46_001847"
     CDS             3596..4231
                     /gene="trmB"
                     /locus_tag="VQT46_001847"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET2371818.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            4357..4836
                     /gene="rimP"
                     /locus_tag="VQT46_001848"
     CDS             4357..4836
                     /gene="rimP"
                     /locus_tag="VQT46_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET2371819.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEIISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            4880..6016
                     /gene="nusA"
                     /locus_tag="VQT46_001849"
     CDS             4880..6016
                     /gene="nusA"
                     /locus_tag="VQT46_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET2371820.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            6038..6331
                     /locus_tag="VQT46_001850"
     CDS             6038..6331
                     /locus_tag="VQT46_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET2371821.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            6324..6623
                     /locus_tag="VQT46_001851"
     CDS             6324..6623
                     /locus_tag="VQT46_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET2371822.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            6640..9432
                     /gene="infB"
                     /locus_tag="VQT46_001852"
     CDS             6640..9432
                     /gene="infB"
                     /locus_tag="VQT46_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET2371823.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     VKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQAAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            9683..10033
                     /gene="rbfA"
                     /locus_tag="VQT46_001853"
     CDS             9683..10033
                     /gene="rbfA"
                     /locus_tag="VQT46_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET2371824.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
     gene            complement(10093..>10659)
                     /locus_tag="VQT46_001854"
     CDS             complement(10093..>10659)
                     /locus_tag="VQT46_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371825.1"
                     /translation="LDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQ
                     DSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDLKHHYQLYQLLLFHFQNKEPEKFF
                     GLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGF
                     RNFENFKKRIFIALNIKKERTKFVLSRA"
BASE COUNT         3235 a         1936 c         2425 g         3063 t
ORIGIN      
        1 attcaagatt tggatgaaaa attttaaaaa acaatgatat actaaacttg tcaaagttgc
       61 aacgggtgct gctacattat gttaaaaatc gctcttgatt gataagctgg atttgttagg
      121 aaaggagtaa ataattatgg ataagaaaaa gatagtttcg actataatat gtatagtatt
      181 tcttgtagtg tcagtagata atttttttag agacttaacc ccgttactgt tcattttaaa
      241 tattattggc ctgtcttgct tttcagtgct aacatacatt aacataaaag agatactctt
      301 aaatataagt aaatgatgat ttggttagtc ctagaaccaa tcaacttatg tttatcggct
      361 tggcagattt tatgtttgtc atttgtttgt atagaggtat ttcagaaaca gaattctatc
      421 aacaactaat cgcttatata ggtgtattct ctgcttgttt atcacgcttc tgctcatgtg
      481 gggcttgaag tattataaaa agtagctttc tatccttttc tgacaggata tttgagtaga
      541 aggctctatt aaattgttag tgaaataaat gaatggaggt atttaatatg aaatacagat
      601 tattttttgt tattttcttg agtagtgtgt tggatattct tttagggaca tttttacaaa
      661 tctctatcgt atctattggg tggcttgttc tttacagtgg tttgtttgaa gtaggagttt
      721 tccttcttgc taataaaggg gtggcggtaa aaatcaagga agtagatatt cgaaatcgct
      781 ttaaatttat ttttggaaaa accttatggt ttcaaattct tttgctcatc tttttgataa
      841 tcaaacttta tcttggtttg gatgcgaggt tgattttatt ctatggacat attttcattg
      901 tctttaatgc cttaatgtat ctattatcta gtagtcaggt tagccttaaa aaaaaacaaa
      961 ctgtcttctt aatcttacag cagtagagtc tgacaaggtg aggtcatagt agggaggatt
     1021 tctatgaaaa agtatcaact tctattcaaa ataagtgcag tcttctctta cttatttttc
     1081 gtatttggtc tttctcagct gacgcttatc gtccaaaatt attggcaatt ttcttcccag
     1141 attggtaatt tcgtctggat tcaaaatatc ttgagtttac tttttattgg agtcatgatt
     1201 gtggttcttg ttaagacagg ccatggttat ctcttccgca ttccaagaaa aaaatggctt
     1261 tggtattcga ttttgacagt attagtggta gtgttccaga tctcttttaa cgttcagaca
     1321 gctaaacatg ttcagtcaac tgcggaaggt tgggctgtat tgattggtta tagtgggact
     1381 aactttgcag agctaggtat ttatatagcc ctgttctttc tggttccact gatggaagaa
     1441 ttgatttata gaggattact gcaacatgct ttctttaagc attcgcgatt tggtcttgat
     1501 ttgcttcttc cttctatttt atttgctctc cctcattttt caagcctgcc tagtctgtta
     1561 gatatcttcg tctttgcaac agttggaatc atctttgctg gtttgacccg ctataccaag
     1621 agcatttatc catcctatgc ggtgcatgtg atcaataata ttgtagcgac cttcccgttt
     1681 ttgctcactt ttctacatag ggtcttgggg taaaaaaaca aaaggcttgc ttttcagcca
     1741 tagaggaggt catcatgtat aaacacttat ttttcctaga ttccaaaact ttagatcggt
     1801 tgacacccta tattctagtc ttggcttctg acaccattgc ttttaatgtt tttgtgctaa
     1861 cctttgtatc tgcggtggtt tttaatttcc taaattccat gctagcttta atggctatat
     1921 tcataggggc tggctatgtg gtcggatttt ggttgctaaa atggtttgtt ttggaaaggt
     1981 tagagctaaa ggatgacgcg taggaagtct gtttggtgag gaggatagtt ttatggagtt
     2041 ttttgataaa tttcatgcct tgtgttttgg atttttagta ctaataattg tcattacagt
     2101 tccttatacg attaaccatg ggggtttttt tcaaaatgaa tctgcattga ttcttgtaag
     2161 tcttcttgta acctcgctga gtgttgctta tgctagaaag tttgaaatga tttcttttgg
     2221 gatgttaagc aagaaacaac ttttgctttt cattgcaatc tttcttctaa gtgtacttga
     2281 gacgctggtt tatattcatt tcttcgctgt ttcttctggc tcaggggtcc aacacttggc
     2341 ggaagtcagc agaggaattt ccctgtcttt gattttgact acctcagttt ttggccccat
     2401 ccaggaggaa ctcattttca gaggacttct tcaaggtgcg gtttttgaca attcttggtt
     2461 agggcttgtg ctaacttcct ctctcttttc tttcatgcat ggaccttcta atgtcccttc
     2521 gtttattttt tatctacttg ggggtttgtt gctgggcttt gcttataaaa agagtcaaaa
     2581 cctatgggtt tctactctag tacacatgtt ttacaacagt tggccactcc tatattattt
     2641 ataaaaatta tgaaaaggta agcagaagac ggtgcttacc tttttcaagc tataatgata
     2701 cccaagccaa tccagaggct tttctttgag aatcgggtta gagtggttga cgaataggcc
     2761 aaaaactagt agaatagtaa ggaaacttta tacggaggaa agaaatggat ttgggtgata
     2821 atgagctaac actgactccc atacctggga aaagtggcaa ggcttatatg ggtagctatc
     2881 ctgacgggaa gcgcatcttt gtaaaaatga acacctctcc aatcctacct ggtctagcta
     2941 gagaacaaat tgctccacaa ttattatgga gtcgtcgttt ggcagatggg cgtgatatgt
     3001 gtgctcaaga atggttgaca ggcaagatat tgacccccta tgatatgaat cgtaagcaaa
     3061 tcgtcaatat tttaacccgt cttcatcgct cacgtccgtt gatgacacaa ttgagtcgtt
     3121 tgggctatgc catggaaaca cctgtagatt tactacagtc ttggcaggaa acggctccag
     3181 atgctttgcg taaaaatcat tttatcagtg aagtgatggc tgatttacgt cagactattc
     3241 caggatttag agaggaccat gcgaccattg tccatggaga tgtacgacat agtaattgga
     3301 ttgagacaga tagtggcttg atttatttag tagattggga ttcggttcgc ttgaccgatc
     3361 gcatgtttga tgtggcccat atgctctgcc attatatttc agaacatcag tggaaggaat
     3421 ggttgaccta ctacggttac aagtacaatc aaacggtatt aagtaaattg tattggtatg
     3481 gtcaattgtc ttatttgagt cagatttcca agtattatat gaaccaagat ttagaaaatg
     3541 tcaatcggga gattcatggt ttgcgtcatt tccgagacaa gtatggaaag agaagatgag
     3601 agttagaaat cgtaaagggg caacagaatt actagaggca aatccccagt atgtggtcct
     3661 caatcccttg gaagccaagg caaaatggcg ggacttgttt ggcaatgata atcccattca
     3721 tgtggaagtt ggaagtggaa agggtgcctt tgtttcaggt atggccaagc aaaaccctga
     3781 catcaactat atcgggattg atattcaaaa gtctgttttg agctacgctt tggacaaggt
     3841 gcttgaagtt ggagtgccta acatcaagct cttgtgggta gatggttctg acttaactga
     3901 ctattttgaa gacggtgaga ttgatcgctt gtatctgaac ttttcagatc catggccgaa
     3961 aaaacgccat gaaaagcgtc gtttgaccta caagaccttc ttggatacct tcaaacgtat
     4021 cttgcctgaa aatggagaaa ttcatttcaa gacggataac cgtggcttgt ttgagtacag
     4081 tttagtgagc ttttctcaat atggcatgaa actcaatggt gtctggttag atttgcatgc
     4141 cagtgatttt gaaggcaatg tcatgacaga atacgagcaa aaattctcaa acaaggggca
     4201 agttatctac cgagttgagg cagaatttta agagatagcc taaaattagg ctgtacaagt
     4261 gcttttgctt tacataagtt ggcaaacgtg ctatactgat agtaagaata tgaaaagtga
     4321 ggcggggaaa tatcttcgcc tcttgcttat gaggaggtgg acgcaatcgc aacaatcgta
     4381 gaattagtca gagaagttgt agaacctgtc atagaagctc cttttgaact cgtggatatc
     4441 gagtatggaa agattggcag tgacatgatt ctcagtattt ttgtagataa acccgaagga
     4501 attaccttga acgacacggc agacttgaca gaaattatca gtcctgtcct agacaccatc
     4561 aagccagatc ccttcccaga acaatatttc ctagaaatta ccagtccagg tttggaacgc
     4621 cctttgaaaa ccaaggatgc cgtcgctgga gcggttggaa aatacatcca tgtcgggctc
     4681 taccaagcca tcgataagca aaaggtcttt gaaggaacct tgttggcctt cgaagaggac
     4741 gagttgacta tggaatatat ggacaagacg cgtaagaaaa ccgtccaaat tccatacagt
     4801 ttagtatcaa aagcacgttt agcagttaaa ttatagaaaa agaaaggata gcttttgagg
     4861 attcaaaagt gaagaaaaca tgagtaaaga aatgctagag gccttccgca ttttggaaga
     4921 agacaaggga atcaaaaaag aagatatcat cgacgcagta gtagagtcgc ttcgttccgc
     4981 ttatcgcaga cgctatggtc agtcagacag cgtagctatt gacttcaacg aaaaaacagg
     5041 tgactttaca gtttatactg tccgtgaagt tgttgatgaa gtatttgata gccgtttgga
     5101 aatcagcttg aaagatgctc ttgccattaa ttcagcttat gaacttggag acaaaatcaa
     5161 gtttgaagaa gcaccagctg agtttggtcg tgtagcagcc cagtctgcca aacaaaccat
     5221 catggaaaaa atgcgcaagc aaacacgtgc catcacttac aatacttaca aagaacatga
     5281 gcaagaaatc atgtctggta cagtagaacg ctttgacaac cgctttatct atgtcaacct
     5341 tggtagcatc gaagcccaat tgtcaaaaca agaccaaatt cctggagaag tttttgcttc
     5401 tcatgatcgt atcgaagttt atgtttacaa ggttgaagac aaccctcgtg gtgtgaacgt
     5461 ctttgttagc cgtagtcatc cagaaatgat caaacgttta atggagcaag aaattccaga
     5521 agtttatgat ggaactgttg aaatcatgag cgtggctcgt gaagcaggtg accgtacgaa
     5581 ggttgctgtt cgtagccaca atccaaacgt ggatgctatc ggtacaatcg ttggacgtgg
     5641 tggtgctaat atcaagaaga ttactagcaa attccaccca gctcgttacg atgctaaaaa
     5701 tgaccgcatg gtaccaatcg aagaaaatat cgatgttatc gagtgggtag cagatccagc
     5761 tgaatttatc tacaatgcca tcgctcctgc tgaggttgac caagttatct ttgatgaaaa
     5821 cgacagcaaa cgtgccttgg tggttgttcc agataacaag ctttctcttg ccattggtcg
     5881 tcgtggacaa aacgtgcgct tggcggctca cttgactggt taccgtatcg atatcaagtc
     5941 tgctagcgaa tttgaagcca tggaagacgc tgcttcagta gagttggaag tagaaaacga
     6001 tactgtagaa gaataaaagc tgctagagga gggaaagatg aaaacaagaa aaatcccttt
     6061 gcgcaagtct gttgtgtcta acgaagtcat tgataagcgt gatttgctcc gcattgtcaa
     6121 gaacaaggaa ggacaagtct ttattgatcc tacgggcaag gccaatggcc gcggcgctta
     6181 tatcaaacta gacaatgcag aagccctaga ggcgaaaaag aagaaggtct ttaaccgcag
     6241 ctttagcatg gaagtggaag aaagctttta tgacgagttg atcgcttatg tggatcacaa
     6301 agtgaaaaga agagagttgg gacttgaata agcaaaagat aagtaatctc ttggggcttg
     6361 ctcagcgagc agggcgcatc atatcgggtg aagaattggt ggtcaaggcc attcaagacg
     6421 gcaaggccaa gttggtcttt ctagctcatg atgctggacc caatctgacc aagaagattc
     6481 aagataaaag tcattattat caagtagaaa ttgtaaccgt gttttcaaca ctggaattaa
     6541 gcatagcagt cgggaaatcg agaaaggttt tggctgtaac agatgctgga tttacaaaga
     6601 aaatgaggtc tcttatggaa tagaagagga ggacatgatt tgtctaagaa aagattgtac
     6661 gaaatcgcaa aagaacttgg aaaagaaagt aaagaagttg tagcgcgtgc aaaagagttg
     6721 ggcttggatg tgaaaagcca ctcatcaagt gtggaagaag ctgtcgctgc aaaaattgct
     6781 gccagcttta agcctgcagc tgctccgaaa gtagaagcaa aacctgcagc accaaaagta
     6841 agtgcagaaa agaaagccga aaaatctgag ccagctaaac cagctgtagc taaggaagag
     6901 gcaaaaccgg ctgagccagt tgctccgaaa acagaaaaag tagcagtgaa accgcaaagt
     6961 cgtaatttca aggctgagcg tgaagcccgt gctaaagagc aggcagaacg acgcaagcaa
     7021 aataagggca ataaccgtga ccaacaacaa aacggaaacc gtcagaaaaa cgacggccgt
     7081 aatggtggaa aacaaggtca aagcaaccgc gacaatcgtc gctttaatga ccaagctaag
     7141 aagcagcaag gtcagcaaaa acgtagaaat gagcgccgtc agcaagagga taaacgttca
     7201 aatcaagcgg ctccacgtat tgactttaaa gcccgtgcag cagccctaaa agcagagcaa
     7261 aatgcagagt acgctcgttc aagtgaggaa cgcttcaagc agtatcaggc tgctaaagaa
     7321 gccttggctc aagctaacaa acgcaaggaa ccagaggaaa tctttgaaga agcggctaag
     7381 ttagctgaac aagcacagca agttcaagca gtggttgaag tcgtccctga gaaaaaagaa
     7441 cctgcagtgg atacacgtcg taaaaaacaa gctcgaccag acaaaaatcg tgacgattat
     7501 gatcatgaag aagatggtcc tagaaaacaa caaaagaatc gaagtagtca aaatcaagtg
     7561 agaaatcaaa agaatagtaa ctggaataac aacaaaaaga acaaaaaagg caataacaag
     7621 aacaaccgta atcagactcc aaaacctgtt acggagcgta aattccatga attgccaaca
     7681 gaatttgaat atacagatgg tatgaccgtt gcggaaatcg caaaacgtat caaacgtgaa
     7741 ccagctgaaa tcgttaagaa acttttcatg atgggtgtca tggccacaca aaaccaatcc
     7801 ttggatgggg aaacaattga actcctcatg gtggattacg gtatcgaagc caaacaaaag
     7861 gttgaagtgg ataatgctga catcgaacgt ttctttgtcg aagatggtta tctcaatgaa
     7921 gatgaattgg ttgagcgtcc accagttgtt actatcatgg gacacgttga ccacggtaaa
     7981 acaacccttt tggatactct tcgtaactca cgtgttgcga caggtgaagc aggtggtatt
     8041 actcagcata tcggtgccta ccaaatcgtg gaaaatggta agaagattac cttccttgat
     8101 acaccaggac acgcggcctt tacatcaatg cgtgcgcgtg gtgcttctgt taccgatatt
     8161 acgatcttgg tcgtagcggc agatgacggg gttatgcctc agactattga agccatcaac
     8221 cactcaaaag cagctaacgt tccaatcatc gtagccatta acaagattga taaaccaggt
     8281 gctaacccag aacgcgttat cggtgaattg gcagagcatg gtgtgatgtc aaccgcttgg
     8341 ggtggagatt ctgaatttgt tgaaatctca gctaaattca accaaaatat cgaagaattg
     8401 ttggaaacag tccttcttgt agctgaaatc caagaactca aggcagaccc aacagtgcgt
     8461 gcaatcggta cggttatcga agcgcgcttg gataaaggaa aaggtgcggt cgcaaccctt
     8521 cttgtacaac aaggtacctt gaatgttcaa gacccaatcg ttgtcggaaa taccttcggt
     8581 cgtgtccgtg ctatgaccaa cgaccttggt cgtcgtgtta aagttgctgg accatcaaca
     8641 ccagtctcta tcacaggttt gaacgaagca ccgatggcgg gtgaccactt tgccgtttac
     8701 gaggatgaaa aatctgcgcg tgcagcaggt gaagagcgtg ccaaacgtgc cctcatgaaa
     8761 caacgtcaag ctacccaacg tgttagcctt gaaaacctct ttgataccct taaagctggg
     8821 gaactcaaat ctgttaatgt tatcatcaag gctgatgtac aaggttctgt tgaagccctt
     8881 tctgcctcac ttcaaaagat tgacgtggaa ggtgtcaaag tgactatcgt ccactcagcg
     8941 gtcggtgcta tcaacgaatc agacgtgacc cttgccgaag cttcaaatgc ctttatcgtt
     9001 ggtttcaacg tacgccctac accacaagct cgtcaacaag cagaagctga cgatgtggaa
     9061 atccgtcttc acagcattat ctacaaggtt atcgaagaga tggaagaagc tatgaaaggg
     9121 atgcttgatc cagaatttga agaaaaagtt attggtgaag cggttatccg tgaaaccttc
     9181 aaggtgtcta aagtgggaac tatcggtgga tttatggtta tcaacggtaa ggttgcccgt
     9241 gactctaaag tccgtgttat ccgtgatggt gtcgttatct atgatggtga actcgcaagc
     9301 ttgaaacact ataaagacga cgttaaggaa gttacaaacg gccgtgaagg tggattgatg
     9361 atcgacggct acaatgatat taagatggat gatgtgattg aggcgtatgt catggaagaa
     9421 atcaagagat aagatttttt gctcctttct taggtggtga gggacgcaag caaaccgatg
     9481 gtttcattgc ttatttttga gcctagggtc tcaaaaatcc cctgtgatgg gactgataaa
     9541 tcagttccat cactttcacc acggcgaaag aagcagatga cttcaaattg aacttcgttt
     9601 caatttaaac tgaaaatcaa gaagtttaaa atagctaggt ctgctggcct agcttttggt
     9661 tcaaagtaga gaaaggaata tcatggcaaa tcatttccgt acagatcgtg tgggcatgga
     9721 aatcaagcgt gaagtcaatg agattttgca aaagaaagtc cgtgatccac gtgtccaagg
     9781 tgtgaccatc acagatgttc agatgctggg tgacttgtct gttgccaagg tttattacac
     9841 cattttgagt aaccttgctt cggataacca aaaagcccaa atcgggcttg aaaaagcaac
     9901 tggtaccatc aaacgtgaac ttggtcgcaa tttgaaattg tacaaaatcc cagatttgac
     9961 cttcgtcaaa gacgagtcca tcgagtatgg aaacaagatt gacgagatgc tacgcaatct
    10021 ggataagaac taaagaagag gggttgcccc tctttttcgg ctctttgtca actgtagtgg
    10081 gttgaagaaa agctaagctc gagaaaggac aaatttcgtc ctttcttttt tgatattcag
    10141 ggcgataaaa atccgttttt tgaagttttc aaagttccga aaaccaaagg cattgcgctt
    10201 gataagtttg atgagattat tggtcgcttc cagtttggca ttagaatagt gtagttgaag
    10261 ggcgttgaca atcttttctt tatctttgag gaaggtttta aagacagtct gaaaaatagg
    10321 atgaacctgc ttaagattgt cctcaataag tccgaaaaat ttctctggtt ccttattctg
    10381 gaagtgaaaa agcaagagtt gatagagttg atagtggtgt ttcaagtctt ccgaataact
    10441 caaaagcttg tttaaaatct ctttattggt taagtgcata cgaaaagtag gacgataaaa
    10501 acgtttatca ctcagtttac ggctatcctg ttgaatgagt ttccagtagc gcttgatagc
    10561 cttgtattca tgggattttc gatgaaactg attcatgatt tggacacgca cacgactcat
    10621 agcacggcta agatgttgta caatatgaaa gcgatcaag
//
LOCUS       DAVAZV010000066        10107 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVAZV010000066 DAVAZV010000000
VERSION     DAVAZV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.066"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(302..1282)
                     /gene="dusB"
                     /locus_tag="VQT46_001855"
     CDS             complement(302..1282)
                     /gene="dusB"
                     /locus_tag="VQT46_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET2371826.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(1269..2141)
                     /gene="hslO"
                     /locus_tag="VQT46_001856"
     CDS             complement(1269..2141)
                     /gene="hslO"
                     /locus_tag="VQT46_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET2371827.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQERHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGAGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            2306..3733
                     /locus_tag="VQT46_001857"
     CDS             2306..3733
                     /locus_tag="VQT46_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET2371828.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLDSAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3892..5400
                     /gene="glpK"
                     /locus_tag="VQT46_001858"
     CDS             3892..5400
                     /gene="glpK"
                     /locus_tag="VQT46_001858"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET2371829.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            5442..7268
                     /gene="glpO"
                     /locus_tag="VQT46_001859"
     CDS             5442..7268
                     /gene="glpO"
                     /locus_tag="VQT46_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET2371830.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKHLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELALSPVDFLLRRTNHMLFMRDSLD
                     SIVEPILDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            7338..8042
                     /locus_tag="VQT46_001860"
     CDS             7338..8042
                     /locus_tag="VQT46_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2371831.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            8339..8542
                     /locus_tag="VQT46_001861"
     CDS             8339..8542
                     /locus_tag="VQT46_001861"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371832.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(8629..9216)
                     /locus_tag="VQT46_001862"
     CDS             complement(8629..9216)
                     /locus_tag="VQT46_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371833.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGTLLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQKKWKFITEYYRNSNYTGYVKTVTTYVNF"
BASE COUNT         2933 a         2009 c         2298 g         2867 t
ORIGIN      
        1 tcaggtgccc ttgcagtcaa cacaactgta gatagctata gagtcaatgc caatggtgaa
       61 tgggtaaact aaacctaata taactagtta atactgactt cctgtaagaa ctctttaaag
      121 tattccctac aaataccata tcctttcagt agataatata cccttgtagg aagtttagat
      181 aaaaaaataa ctctgtaatc tctagccgga tttatagcgc tagagactac ggagtttttt
      241 tgatgaggaa agaatggcgg cattcaagag gctctttaag agagttacgg gttttaaact
      301 attaagcctt ctccaattgc aagagggctt caatctctgc cagggtgcta gcttgcgaaa
      361 tggctccacg gagtttggca gcgccagatg ttccacggag atagtgagga gcgaggccgc
      421 ggaattcacg aactgcgacg ttttctcctt tgaggttaat caatcgtttc aagtgttcgt
      481 aggcgatctt catcttgtct tcaaaggtca aatcaggtag gatttctcct gtttcaaagt
      541 aatggttgat ttggttgaag aggtaaggat ttcccatggc agctcggcca atcatgactg
      601 cgtcagcacc aacttcttcg atgcgttgct tggcttcttg gacagtacgg atatcaccgt
      661 tggcgatgaa tggaatcttg gttagagctt gggcaacctt gtaaagggtc tcaaggtctg
      721 cgtggccagt atacatttgt tcacgggtac ggccatgcat ggcgagggca gaaacacctg
      781 cagcctcagc agcgagggca ttttctactg caagagatgg gtccgcccat ccggtacgca
      841 ttttgacagt aagtgggata tcaaggacag actggacctt gttgatgata gagtagatct
      901 tgtcaggatc cttgagccac atagctccag cttcgttctt cacgattttg ttgacagggc
      961 agcccatgtt gatatcgacg atatcggtct tggtgttttc ttggatgaat tctgctgcgc
     1021 gtgctaggct gtcttcatcg ctaccaaaaa gttggataga gacagggttt tcgccctcat
     1081 cgatatgaag catgtgcagg gttttttcgt tgttgtattg gattcccttg tcagagacca
     1141 tttccattac aacgagtcca gctccgagct cttttgcgat ggtacgaaag gctgagttgg
     1201 tcacgccagc cataggcgct aaaacggtac gattgggaat ctcaatattg ccaatcataa
     1261 aaggtgtatt aagatttgtc acgaatgagt tcctccaggt ccttttcatc aaagttgtaa
     1321 gtagtttggc agaattgaca agtgatttct gccccgtggt cttcctcttt catttcctgt
     1381 aagtctgagc ttggaaggct ggcaagagcg ttcataaagc gttcatggct acagtcacat
     1441 tggaaacgga tttcttcttc agaaagacgc ttgtaggctt cgtccccgta gatagccttg
     1501 aggagggctt cgatatggtc gtcgctttcg agaagagtag agatagctgg catttcttgg
     1561 atgcgttttt caaagcgagc aatctcttct ttcttggctc ctggcaagac ttgaactagg
     1621 aaaccacctg caaccttgac cttgtcttcc tcgtccaaaa ggacattgag gccgaccgct
     1681 gaaggcgttt gttggctttc agtaaggtaa aaggcaaggt cttcaccgat ttctccagag
     1741 atgaggggag ttatagagtt gtaaggattt ccagcaccgt agtctgtgat aacgaggaat
     1801 tgaccatttc caacaaaagg tccgactagg acttcaccag tcgcagtctt tttgatgtca
     1861 acaccaggat tttgaacata gcctttgacg ttccccttgg tatcagcgac ggtgataata
     1921 gcacctagag agctagagcc caacacctta actgtaagtt tggtatttcc tttttcattg
     1981 gctgcgagaa tctggctagc gataagagtt cgaccaagcg ctacagttga gctagcttgg
     2041 gtttgatgtc tttcttgagc agtgcggacg gtttccgtgc tatcaaggac aaaagcacga
     2101 aaggctccgc tttctgatat agttttaata attttatcca tagctactat tttagcataa
     2161 aaatgcccaa agggggagcc gtgtgtttac tgattttcag gataatggac caggaaatca
     2221 gcatgaaaat aaaaagagaa acagattatt tcagcatttg taagatttat gctatgctta
     2281 aggtagaaaa tgaaaggggt aacaaatgta tttaggagat ttgatggaga aagccgagtg
     2341 tggtcaattt tcaatccttt cctttctatt acaagagtct cagacgaccg tcaaggctgt
     2401 aatggaagaa acaggatttt caaaagcaac cctaaccaaa tatgtcaccc tgctcaatga
     2461 caaggctttg gatagtggct tagaactgac tattcactca gaagatgaaa atctgcgtct
     2521 gtctatcggt gcagctacca aggggagaga tattcggagc ttgtttttgg atagtgctgt
     2581 taaataccag attttggttt atcttctcta ccaccaacag tttttagccc atcagctggc
     2641 tcaagaattg gtgattagcg aggctacgct tggtcgtcac ttggctggtt taaatcagat
     2701 tttgtcagaa tttgatttat ccatccaaaa tggacgctgg agaggtccag agcatcagat
     2761 tcgctatttc tatttctgtc ttttccgaaa ggtctggtcg agtcaggaat gggaaggtca
     2821 catgcagaaa ccagagagaa aacaggagat tgccaattta gaggaaatct gcggtgcaag
     2881 tttgtctgcg gggcagaaat tggacttggt tctctgggct cacatcagtc aacaacgtct
     2941 tcgggtcaat gcttgtcagt ttcaagtcat agaagagaaa atgcgagggt attttgacaa
     3001 tatcttttat cttcgtttgc tgagaaaggt tccgtccttt tttgctgggc aacatattcc
     3061 actaggagtt gaggatggtg agatgatgat attcttctct tttctcctat ctcatcgcat
     3121 tcttcctctt catactatgg agtatattct tggttttgga gggcagttgg cagatttact
     3181 gacgcaattg attcaagaaa tgaagaagga ggaactattg ggggattata cagaggacca
     3241 tgtcacctat gaactcagtc agctttgtgc tcaagtctat ctctataagg gctatatttt
     3301 acaggatcgc tacaagtacc agttagagaa tcgtcatcca tatttactga tggaacatga
     3361 ttttaaagag acagcagagg agatttttca tgctctacct gcttttcaac aggggacaga
     3421 tttagataag aagattctct gggaatggct ccagttaatc gaatatatgg ctgaaaacgg
     3481 tggccagcat atgcggattg gtctggattt gacatctggt tttcttgtct tttcaaggat
     3541 ggcagccatt ttgaaacggt atttggaata caatcgtttt attaccattg aagcttatga
     3601 ccctagtcgg cattatgatt tgctggttac caataacccg attcataaga aggaacagac
     3661 accagtctat tatttaaaaa acgacttgga tatggaagat ttggcaggga ttcgtcagtt
     3721 attattcact taaaaggctt ggttaatcta ggtctttttt gtgaaattca cacaatctcc
     3781 tcacattttt ttaaaaatta aaaaaagttg ataaacaaga aagcgcttta ttttgtatac
     3841 tagtaagtgt aaagaggaaa cacctcaaga tctttatcag gaggacagta catgtcacaa
     3901 gaaaaataca tcatggccat tgaccaggga actacaagtt ctcgtgccat cattttcaac
     3961 aaaaaagggg aaaaggttag ctcgagtcaa aaagagttta cccagatttt ccctcaggca
     4021 ggttgggttg agcacaatgc caatgaaatt tggaactctg ttcagtcagt tattgcgggt
     4081 gctttcatcg aaagtggtgt caagccaaat caaatcgagg caatcgggat taccaaccaa
     4141 cgtgaaacaa cggttgtctg ggataagaaa acaggacttc ctatctacaa tgctatcgtt
     4201 tggcagtcac gccagacagc acctttggct gagcaactaa aaagccaagg ttatgtggaa
     4261 aaattccatg aaaagactgg tttgattatt gatgcttact tctctgctac caaggttcgt
     4321 tggattttgg atcatgtaga aggtgctcaa gagcgagcag aaaaagggga attgctcttt
     4381 ggtactatcg atacttggtt ggtttggaaa ttgactgacg gtgcggctca cgtgactgac
     4441 tactcaaatg cagctcgtac catgctttat aacattaaag aactcaaatg ggatgatgag
     4501 attttggaaa tccttaacat tccgaaggct atacttccag aagttcgttc taactccgaa
     4561 atctacggca agacagctcc attccatttc tacggtggag aggtgccaat ctcaggtatg
     4621 gctggggacc aacaagcagc cctctttgga cagttggctt ttgagccagg tatggttaag
     4681 aatacttatg gaacaggctc tttcatcatc atgaatactg gggaagagat gcagttgtct
     4741 gaaaacaacc tcttgacaac cattggttac ggaatcaacg gtaaggttta ttatgccttg
     4801 gaaggttcta tcttcatcgc aggaagtgct attcagtggc ttcgtgacgg tcttcgcatg
     4861 gttgaaaatt caccagaatc tgaaaaatac gctcgtgatt ctcacaacaa cgatgaagtt
     4921 tatgtcgttc cagcctttac aggtctaggc gctccatact ggaaccaaaa tgctcgtggt
     4981 tccgtctttg gtttgactcg tggaacaagc aaagaagact ttatcaaggc gactttgcaa
     5041 tctattgctt atcaagtgcg tgatatcatc gacaccatgc aagtggatac tcagaccgcc
     5101 attcaagtac tgaaggtgga tggtggtgca gccatgaaca acttcctcat gcagttccag
     5161 gcggatattt taggcattga cattgcacgt gctaaaaacc tggaaacaac agctctagga
     5221 gcggccttcc tagcaggttt gtcagtaggg tactggaaag acttggacga gttgaaactc
     5281 ttgaacgaga caggagaact ctttgagcca tctatgaacg aatctcgcaa ggaacaactc
     5341 tacaagggct ggaagaaggc tgtgaaagca actcaagtct ttgcggaagt agacgactaa
     5401 tactggcaga ataaagcgat ttatttagaa agtgtgtaaa tatggaattt tcaaagaaaa
     5461 cacgtgaatt gtcaattaaa aaaatgcagg aacgcaccct ggacctcttg attatcggtg
     5521 gaggaatcac aggagctggt gtagccttgc aggcggcagc tagcggtctt gagactggtt
     5581 tgattgaaat gcaagacttt gcagaaggaa catctagtcg ttcaacaaaa ttggttcacg
     5641 gaggacttcg ttaccttaaa caattcgacg tagaagtggt ctcagatacg gtttctgaac
     5701 gtgcagtggt tcaacaaatc gctccacaca ttccaaaacc agacccaatg ctcttaccag
     5761 tttacgatga agatggagca acctttagcc tcttccgtct taaagtagcc atggacttgt
     5821 acgacctctt ggcaggtgtt agcaacacac caactgcgaa caaggttttg agcaaggatc
     5881 aagtcttgga acgccagcca aacttgaaga aggaaggctt ggtaggaggt ggagtgtatc
     5941 ttgacttccg taacaacgat gcgcgtctcg tgattgaaaa catcaaacgt gccaaccaag
     6001 acggtgccct cattgccaac cacgtgaagg cagaaggctt cctctttgac gaaagtggca
     6061 agattacagg tgttgtagct cgtgatctct tgacagacca agtatttgaa atcaaggccc
     6121 gtctggttat taatacaaca ggtccttgga gtgataaagt acgtaatttg tctaataagg
     6181 gaacgcaatt ctcacaaatg cgcccaacta agggagttca cttggtagtg gattcaagca
     6241 aaatcaaggt ttcacagcca gtttactttg acacaggttt gggtgacggt cgtatggtct
     6301 ttgttctccc acgtgaaaac aagacttact ttggtacaac tgatacagac tacacaggtg
     6361 atttggagca tccaaaagta actcaagaag atgtagatta tctacttggc attgtcaaca
     6421 accgctttcc agaatccaac atcaccattg atgatatcga aagcagctgg gcaggtcttc
     6481 gtccattgat tgcagggaac agtgcctctg actataatgg tggaaataac ggtaccatca
     6541 gtgatgaaag ctttgacaac ttgattgcga ctgttgaatc ttatctctcc aaagaaaaaa
     6601 cacgtgaaga tgttgagtct gctgtcagca agcttgaaag tagcacatct gagaaacatt
     6661 tggatccatc tgcagtttct cgtgggtcta gcttggaccg tgatgacaat ggtcttttga
     6721 ctcttgctgg cggtaaaatc acagactacc gtaagatggc tgaaggagct atggagcgcg
     6781 tggttgacat cctcaaagca gaatttgacc gtagctttaa attgatcaat tctaaaactt
     6841 accctgtttc aggtggagaa ttgaacccag caaatgtgga ttcagaaatc gaagcctttg
     6901 cgcaacttgg agtatcacgt ggtttggata gcaaggaagc tcactatctg gcaaatcttt
     6961 acggttcaaa tgcaccgaaa gtctttgcac ttgctcacag cttggaacaa gcgccaggac
     7021 tcagcttggc agatactttg tcccttcact atgcaatgcg caacgagttg gctcttagcc
     7081 cagttgactt ccttcttcgt cgtaccaacc atatgctctt tatgcgtgat agcttggata
     7141 gcatcgttga gccaattttg gatgaaatgg gacgattcta tgactggaca gaagaagaaa
     7201 aagcaactta ccgtgctgat gtcgaagcag ctctcgctaa caacgattta gcagaattaa
     7261 aaaattaaga aaaaataaaa gaggtggagg gcagcattcc ttgtcgcccg tcccttcttt
     7321 ttaatggaga cagaaagatg atgaatgaat tatttggaga atttctaggg actttaatcc
     7381 tgattcttct aggaaatggt gttgttgcag gtgtggttct tcctaaaacc aagagcaata
     7441 gctcaggttg gattgtgatt actatgggtt gggggattgc agttgcggtt gcagtctttg
     7501 tatctggcaa gctcagtcca gctcatttaa acccagctgt gaccatcggt gtggccttaa
     7561 aaggtggttt gccttgggct tccgttttgc cttatatctt agcccagttc gcaggggcca
     7621 tgctgggtca gattttggtt tggttgcaat tcaaacctca ctatgaggca gaagaaaatg
     7681 caggcaatat cctggcaacc ttcagtactg gaccagccat caaggatact gtatcaaact
     7741 tgattagcga aatccttgga acctttgttt tggtgttgac aatctttgct ttgggtcttt
     7801 acgattttca ggcaggtatc ggaacctttg cagtgggaac tttgattgtc ggtatcggtc
     7861 tatcactagg tgggacaaca ggttatgcct tgaacccagc tcgtgacctt ggacctcgta
     7921 tcatgcacag catcttgcca attccaaaca agggagacgg agactggtct tacgcttgga
     7981 ttcctgttgt aggccctgtt atcggagcag ccttggcagt gcttgtattc tcacttttct
     8041 agtttatact cttcgaaaat caaattcaaa ccacgtcagc gtcgccttac cgtactcaag
     8101 tacagcttac ggctagcttc ctagtttgct ctttgatttt cattgagtat tagaaaacaa
     8161 ttatgttgat agagcttggg caagagccca atttcagcaa aaaatgaagt aaatcttctc
     8221 ataataaaac gcatcatatc aagcacgaaa attccacgag gtcaactaca gtcagaaagc
     8281 tgaacaacaa gccaaaacgc ccaaaaaagg cggcaaaaag caagcacctg caagcaacgt
     8341 gccgaaatgg tcaaatcctg attatgtcaa cgaattagac ccaaaaatcg ttgatatgct
     8401 agtagaattt cacaagtcac aaggcacttt ggaaactccc gaggcgcaag cagaaatcgc
     8461 ccaaaaacgt gaagaaatcg agcaaaggag agctgagctt gaggataaaa aacaagagct
     8521 tttgaaccgc ttgaacaaat agagtttcgc aagtattatg cttacaaatt acttgagcaa
     8581 ttaactaaaa tataaaccct gcctttatat ctaggcaggg tttatatttt agaaattcac
     8641 gtaggttgtt acggttttta catacccagt atagtttgag tttctatagt attcagtgat
     8701 aaacttccat tttttttgag caacatggat ataagtactt gttatgtagt atggatatgg
     8761 gctttgtgaa tccaagtaag actgataagc ttgtatacca aaatatgctc caccaattat
     8821 tgcaccccat ggacccccca ataaagtacc tatcctacca atcatataac tgattccagc
     8881 accagtcatg aagttagcga atgtgttagc ttgtttattc ccatgtattg tgttgacgta
     8941 attccaaaca ttaggatcgt atgatctaaa agatatattt aggtcgattt cattcttttg
     9001 ataagccata taaaatgccc cattgatata gacgccgtca gcacgtcgtt caatagtgtc
     9061 tacacttcca tctggattga caacctcaag aacttcatcg cttaaaatat ttacttgcgt
     9121 atctccgaac cgcactgatg agccattctc aaactgagcc tcaccagata caactttaga
     9181 gtttgccgat aagctatcat cagcaaaaac aaacaagcga cggggaaatg ctagacatac
     9241 agaaaacaga cataactagc aaacacatgc atttaaacat cttagacata acggaaactc
     9301 ctttgtattt ttgatttttt tcaactttta ttatacaata aaaccaaata aaaagaaagc
     9361 ggtaacaata tgcttaatgc gaaaattttt tatatatttt tatgtttgat cgttatcgaa
     9421 actacaggct tgttgttgtt gaaaagaggt ctcgaaatgg gttatttaga cacagaagct
     9481 attatcctcg cagttttttc atttgctttt tacaacctat gttcattcgc ttgggtctgc
     9541 tctacaataa aaaacaataa aaaataaata gacgtatttt caaaaaaaaa aaaaaaaaat
     9601 gcatatttat cttagcaaaa cgacaattta aatcgtcgtt tttttgtagt acgacgggca
     9661 tgtcgtatat ctgaggtgta agtcctcggt gggcacctgc taccggtgaa cccaatagcg
     9721 attcccaagc ctgactatcg tgaggtagca gggagaggaa gggatagcga aatcgtggct
     9781 ctacgaacag gaacgtgata gtaaggcgta tatagcggat aaggaggctt caaactctaa
     9841 agtccaaaaa ggtagtcgta acctatatgt gtaaatcacg agagtaattg aattcggact
     9901 aaggtttgtg tgaaaaagat aaatctttct agagtctaaa gactctgcgt cagatttcct
     9961 attttcactg taacctttta acgtcctcat atcttgtata aacgaggaaa gatgtacgac
    10021 ttatcccgtg aggtttcatg agcgctgaaa gcgtagtaac aacgaatcat gagaagtcag
    10081 ccgagcccat agtagtgagg aaacttc
//
LOCUS       DAVAZV010000067        10041 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVAZV010000067 DAVAZV010000000
VERSION     DAVAZV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10041
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.067"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(17..1918)
                     /locus_tag="VQT46_001863"
     CDS             complement(17..1918)
                     /locus_tag="VQT46_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET2371834.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDMLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYYFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYRELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEILSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            complement(1940..2233)
                     /locus_tag="VQT46_001864"
     CDS             complement(1940..2233)
                     /locus_tag="VQT46_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET2371835.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQTEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            complement(2233..3051)
                     /locus_tag="VQT46_001865"
     CDS             complement(2233..3051)
                     /locus_tag="VQT46_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET2371836.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVVIGIIGSWLKIIA"
     gene            complement(3038..3817)
                     /locus_tag="VQT46_001866"
     CDS             complement(3038..3817)
                     /locus_tag="VQT46_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET2371837.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTANHVVEEEAHDDWI"
     gene            complement(3832..4323)
                     /locus_tag="VQT46_001867"
     CDS             complement(3832..4323)
                     /locus_tag="VQT46_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET2371838.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLACNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            complement(4334..5524)
                     /locus_tag="VQT46_001868"
     CDS             complement(4334..5524)
                     /locus_tag="VQT46_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET2371839.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            complement(5536..5964)
                     /locus_tag="VQT46_001869"
     CDS             complement(5536..5964)
                     /locus_tag="VQT46_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET2371840.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPVKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEDFESGI"
     gene            6235..7050
                     /locus_tag="VQT46_001870"
     CDS             6235..7050
                     /locus_tag="VQT46_001870"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET2371841.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            7069..7710
                     /locus_tag="VQT46_001871"
     CDS             7069..7710
                     /locus_tag="VQT46_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET2371842.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            7741..8742
                     /locus_tag="VQT46_001872"
     CDS             7741..8742
                     /locus_tag="VQT46_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET2371843.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            8752..9381
                     /locus_tag="VQT46_001873"
     CDS             8752..9381
                     /locus_tag="VQT46_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET2371844.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(9760..10041)
                     /gene="tnpA"
                     /locus_tag="VQT46_001874"
                     /pseudo
     CDS             complement(9760..10041)
                     /gene="tnpA"
                     /locus_tag="VQT46_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         3004 a         2227 c         1834 g         2976 t
ORIGIN      
        1 ttcaaaatgc ctatttctag cactgcaagc gaatcattct ctcatttatt ttatcatata
       61 ctagacattt tccacgcatt tttgttccgt caacgaggca caatttttca cctacacaaa
      121 tatcctcgct taataacaga atcagcttgt ctgtttcgtc atttttcact tcaaaagcca
      181 gagcattttc cacttcacga tcatctgtct ggtagacaga atgacggatg atttcaaaac
      241 tctcatgcgc aatgatggta taatccagca tctgattctc aaagaattgg cgcttggtga
      301 gtttgttact tctttcaagc tcattgtatt taggagaaat gatggtatct tccaaatcaa
      361 aatcaacttc actccatagt ctcaactgat tgattttccc atcttgatag gtcacatcct
      421 tgtcaaggat aaactgagtc aacgcctcat gctgaccttg acacctgatg tcatccacca
      481 agagccagac atcctctacc aacatgagga tttttctctt gtgaagataa ggcaaatcag
      541 gttctgctga ccaataagcc ccttcaatat aatgcactcc ctccctttct ttatggtgac
      601 aaaacaggga gtgaggatag tattcatatt cccaggatcc cgtgattctt tccggagctt
      661 tcccatctac aatgcaggtc gaatgactcc aagcactctt taagagataa cgttcatata
      721 tctcccgata agaataacgc ccagcatcta tgaaaatagg ttgtccttga tactgtaagc
      781 aaaaactatt ctcgtcacta tggctatggg cacttcctag cggaccattt ttgaaaaata
      841 gataacgatg ttcatcctta atgcagacat gtccagagtc ttcaaagatc atggacttag
      901 gctgccaagc tctcttttca aattcctgca gtcgcttgac cttttctcgc cccaggaaca
      961 agaggctaag caaatcgact ttaacatcca gaccgttaag aaggtcttcc ttgttcaaaa
     1021 ccacagcaga caggctcaaa atttctgtcg tttctgtaga atcgctatca ccaaaagcca
     1081 aagttcgtcc atctaagcct gtcatcattt gaatataggt cgccatcttt tccagcaact
     1141 ctcggtaact atcttgcaag tctggaagca agagacacaa atccagcaag gctttataaa
     1201 cctctacatg atagagaatc gactgttcaa actggcttcc atctcctaaa atctgtgtct
     1261 caatttgctg tttcaactcc tctgaagcaa aatggtaagc ttcttctagg tccatcttat
     1321 ctgaaaagaa ataatagata gcaagcatcg gaattgtttg taaaatcccc cagttactaa
     1381 gggtgtactt ggcgcgatag tagcttttca taaagtcaat ctgcttttct agactgacca
     1441 aaattttctc tagttctttc tcctctagca tgtcaaattt caagaggagc aagagtagtt
     1501 tcaaccaagt aaaggaacga atacccgtat ccaaggttct agtcatcaag gattgaggag
     1561 aaaattctct cacctgctca atccaatcaa atagaaagaa cttgcacttt tgaatatagt
     1621 ccttatctcc ttctaccaca taccctatca taaactgcaa gagatattct tgtcgattga
     1681 gcatataagc ccattctgga tcatcttcaa atacttgatc ccataccatc ggctggattt
     1741 gatggatttt tgaacaaggc tccatatccc aaggactatc aaacataaaa cgattgtcca
     1801 tcaagcgttc aagggaactc ttgactttct catagtcttt tgaacagtgc gacaagatat
     1861 aatcacgaca ttggtttcca tcgactcttt caaaaaattg tcttctttct tctttcatta
     1921 tctattacca gaaaaagaac tacttaaaaa gcagttcttt tgtctttccc attacacttt
     1981 ccttttctac atagatgacc acaccttttg caatctgcaa ggagaccaag tcatctttga
     2041 tagaaatgat ttttccatga attccagaca ataacaacac ttcatcacca gatgttaaag
     2101 aagctaaata ctcttgtcgt tgctccgtct gtttgcgaag caacttttgc tgacgaatag
     2161 aatgaaagct tgacagtaaa aggggactca ctgccaagac aatcactatt ccataaaaca
     2221 atgttgtatc cattaagcta taatcttaag ccagcttccg ataattccga tgacaactgt
     2281 taaaataacg agtttatatg ttgtccattt cttttctttg atcaagtagt aaactaaaag
     2341 tgtaaatagg gctggtagaa gagctggagc aaccttatca agcattccct gaatacttac
     2401 gatactttgt ttagcgtctg ctttaacttc ccctgcagca aaggtaatcg gcaccataat
     2461 cttaacagat gtcgctgcca aaccagcaat tacggttaca ccgataatat tggcaatacg
     2521 agaaatcgtt gccatctgtt cgcttagttt atcaatcaca gttgttccta gtttgtatcc
     2581 atacagacca gttgacaatt taatcgctgt taaaatcgta ttcatcgcaa ggaagaacaa
     2641 gattggaccg acaaccaagc cttcttgagc aaacgaagct gcgatggttg agaacaatgg
     2701 agctaaacag aattgagaaa gagaatcccc aatacctgcc aatggtccca tcaaggccat
     2761 cttgatgcta cgtgtttctt ttgccggacg gccattttcc aacattacaa gatgcaagct
     2821 ggtaataaaa ggcaggaagt gtgggttggt attatagaat tcacagtttt cttccaaggc
     2881 ttggtagaaa ccttcctgat cctctccata gtgttttttc aaagcaggat acatcacatt
     2941 ggcatatccc aacccttgat agttactata gttaaatcca ttttgacaaa agaatgcccg
     3001 caaagacgtt ttaagataat cacgttttgt taatttgtta gatccagtca tcgtgtgctt
     3061 cctcctctac cacatgattc gctgtttttg gcttgttata aaattcaatc aaagcaaaga
     3121 tagtacctac aattgcaata ccaattgttg ggatgtttag ataagctgca caaacatatc
     3181 ccaacaagac aaagggaatc aactctttct tagccatcac tgacaagatc atcgcaaaac
     3241 cgatagctgg gagcatttta ccagcaactg tcaaacctgt aagtaatacc ggtggaatgt
     3301 agtctacgag tttcaacaag gtatccattg aaagggcacc caagcaaccc aaggtaaatc
     3361 caataaaggc aaacaaccaa attgttgcat ttagagtaaa cttgaatttc ttcaaattat
     3421 ggtttttcaa gtgcttcatc gccgtttcag gcgcaccagc acgtacagtg taggcgaaag
     3481 tttgtaagaa ttgaatcgcc acagcaatcg gagtagagag ggcaagagcc gcttctggac
     3541 tgactttacc agcactagtg atagccatca aggtaccaaa gataccaggt ccgattgggt
     3601 ttggtggaac agtacctcca gcaccaacac cgaatcccat ataagccaat tcaccaatag
     3661 ctcccattgc aagagcagta ggcagatcac ctagaataat tccgacacca aatgacagaa
     3721 caatacatct attggtgtaa attcctaaca gcattccact aaaacagaaa gctgtccata
     3781 atccaattaa aatcgcttga aatacattaa tcgacataac gatctcctct tttaaatata
     3841 gtccataatg ttgacttgaa cagctccatc atttcctgtt ggagttgttt tcgtattaaa
     3901 tgttacttga tgagtttggc ttaattcctt gagggctgcc ttgtcctctt cacccaggaa
     3961 gatggagcgt gtcacttgct ctttaccagg ggcattgtga atgttcccaa tattgatttc
     4021 tttgataggg acaccacctt ctaccaaggt taaagcgtcc tttacatcct ttacaacgat
     4081 aaagatcgtt tgagcaggat tagccttgtg aatgatatca atcacctttt gcaaagggaa
     4141 gaaacgcatg gcaactgagt ctggcacaac tgttttcatc agagtttgtt gcatcttgtc
     4201 cgtgcttact tcgtcattgg caacaatgac cgtattacaa gctaggtatt ttacccaaag
     4261 ttgtccttgt ccatgaatca accgttcatc gatacgggtc ataataatat ttggcattgt
     4321 catatttctc ctcctaccaa tataggttcc agtctttgta gaaacggata agggcttcta
     4381 ggtaatagta gtcaccccag atattgcctt catccactcc tttacctgaa tgccatgagt
     4441 acacaccgtg gagaagactt gtcccaccag gggtaaattg atcatttgca taatgttcga
     4501 tcaaggaacg aagcatggca tgcatagcat gtttataaat atctttgtca gcatccacct
     4561 ctgggagatg ttttagcatt tcatgaatcc cacagacggc gatagctgtt gctgaagaat
     4621 ctcgtgattg agcactacca tcattaaaaa tcaaatccca ataggacaca tgatcttttg
     4681 gcagacgatt caagaaataa ttggtcacac ccttaaacaa gtcaaagcag gactcgtctt
     4741 ttaagtgacg ataagtcaaa ggaataccat agactcccca tgattgacca cgtgcccagc
     4801 atgaatcatc actataccct tgtctcgtta cacctttaaa gggttgacct gtctcaggat
     4861 caaaatagaa ggtgtggaag gacgaagcgt catcacggat tacattatta gctgaagcat
     4921 agaaatgact ttctgcaata tcgtagtatt tttgatcgcc tgtttcttga taagcaaaga
     4981 ataagagttg gatattgagc aagcagtcga taatcaaacg gtaatgctct ttcttgccca
     5041 agtctcccca agcttgaata aaaccacctt tttcttgata gcgttcaatc aacttatctg
     5101 cagctttcaa ggttgcttct ctagcctctc catctccatt tatcttatat tcagccatac
     5161 aagacggtgt gtacaagaag ccgagatcat ggtgatccaa ttctactctc ttattgacac
     5221 gatccaggaa agaaagaaca tttttatgag cgatgttttt aaatgcatcc tgttgactgt
     5281 attcataagc caaccacagt tctcctgtcc agaaaccatt ggtccattcc gtgttatcca
     5341 tgattggata gacattatca aaggtagctg gcgtcgggaa atcttccttg aaatagtcaa
     5401 ggttgagttc taactgccga ataaccttat cgattgcctg gccgacttct tctttcgtca
     5461 gaagtggtac ttctaagaag cgctcaggcg attttatttt ttcaatcgta acctttttta
     5521 tcattctttt accctttaaa tacccgattc gaaatcttct tcctctgcat ccgttgaaaa
     5581 caattcttta ccatttacga ctccgccctg ggccgccact actgatttat taacaacctc
     5641 atcaaagcta tgagccattc tagcaaagac tgcttccatt aacatggcta agttcaaacc
     5701 cgagagaaca ttcattgttt tgactggatt ttctcccatt atggtagaag aaaccttgaa
     5761 tggcgatcct cccaagagat cacttaggat taaaacttct tcttcatttg aaattgcaag
     5821 taagattttt tgcttgagtt catctgctga cattccttcc acaaagtcaa tcgcctccac
     5881 attttcttga ttacctgcaa tcaattgtaa agaactataa atccctgtag caaaatgtcc
     5941 atgccctaca agtacaattt tcatcttttc tcctttcttg tttaggttta ccggtttact
     6001 ttatattccc cattgtaatc ctttattttt atcttgtcaa tagttttttt aaaaaaatat
     6061 tagcgctttc attatctttt taaccatttt aataaacaga aatttcaaaa cattccgttt
     6121 ttcaggaaaa caaatctttt tataaataaa aatatttatt tattgacaaa accggtttgc
     6181 tagaatataa tttggttata gagaagtctt aacaaatttg aaaggaagta tcaaatgaca
     6241 aatacatcat tctcaattga gcagttttct ttaaaaggaa aaattgctct catcaccggc
     6301 gcttcttatg gaattggatt tgctattgcc aaatcctacg ctgaagccgg cgctactatt
     6361 gtctttaacg atatcaatca agatctggtc aataaaggga ttgaagctta tcgtgaagtt
     6421 ggcatcgaag cccatggata tgtctgtgac gtgacagacg aggacggtat ccaagccatg
     6481 gtcaagcaaa tcgaacaaga ggttggtgtc attgacatcc tcgttaataa cgctggtatt
     6541 atccgccgag ttccaatgtg cgaaatgagc gccgctgatt tccgtaaggt catcgatatt
     6601 gacttaaacg caccatttat cgtttcaaag gcagttattc cttctatgat aaagaaaggg
     6661 catggaaaga ttatcaatat ttgttcgatg atgagcgaac tgggacgtga aacagttagc
     6721 gcttatgctg ctgctaaagg gggcttgaaa atgttgaccc gcaacattgc gtctgaatac
     6781 ggtggagcca atatccaatg taacggaatt ggaccgggtt atattgccac tcctcaaaca
     6841 gcacctcttc gtgagttgca agaagatggt tctcgccacc catttgacca gttcatcatt
     6901 gcaaaaacac ctgctgcacg ttggggaaat cctgaagatt tgatgggccc tgctgtcttt
     6961 ctcgctagtg atgccagcaa ttttgtcaat ggccacatcc tatatgtaga tggcggtatc
     7021 ttagcctaca tcggaaaaca acctgagtaa aaatagaaag aagatcttat gaaaatcgca
     7081 ttaatcaatg aaaatagtca agctagcaag aatcacatta tttacgatag tctaaaagaa
     7141 gcgacagata aaaaagacta ccaattattt aactatggta tgcgtggaga agaaggagaa
     7201 agtcaattaa cttatgtgca gaacggacta atggctgcca tccttttaaa tacaaaggca
     7261 gttgactttg ttgttaccgg ctgtggtacg ggtgtagggg ctatgcttgc tttaaacagc
     7321 ttccctggtg ttgtctgtgg tctagcagtg gacccaactg acgcttacct ttattctcaa
     7381 atcaatggtg gtaacgcctt gtctatccct tatgccaaag gatttggctg gggggcagaa
     7441 ctgaccctca aattgatgtt tgaacgctta tttgctgaag aaatgggcgg tggctaccca
     7501 agagaacgtg taatccctga acaacgcaac gctcgtatct taaacgaggt gaaacaaatc
     7561 acccacaatg atttgatgac catccttaaa acaatcgacc aagacttcct caaagacacc
     7621 atctctggca aatacttcca agaatacttc tttgaaaact gccaagatga tgaagtcgct
     7681 gcttatttga aagaagtatt agccaagtaa agctattcta aaccagaaag gaactaatgg
     7741 atgacgaaaa tattactgtt tggcgaacca ttaattcgaa tctcaccatt agatgccacc
     7801 agtatcggcg atcatgttgc cagttcgact tattttggcg gatcagaaat taacatcgct
     7861 tgtaatttgc aagccctggg tatctcaacg aaagtcttta ccgcactccc tgccaacgag
     7921 attggagatc gttttctcac attcttgaaa cagcaccaaa tcgataccag ttcaatctgt
     7981 cggcttggcg atcgaatcgg cctctactat ttggagaacg gctttggttg tcgtcaaagt
     8041 gaagttttct acgatcgtaa gcatacgagt atcagccaga ttcggccaaa catgctagat
     8101 atggattctc tctttcaggg gattagccat tttcatttta gtggaatcac catagctatc
     8161 ggtcaagagg tccgtgcgat ccttctccta ctcttggaag aagccaagcg ccgaggaatt
     8221 gtcgtttcaa tggatctcaa tctgagaaca aagatgattt cagtcctaga agccaagtat
     8281 gaattttcta agtttgcacg ttttactgac tattgcttcg gtattgatcc tctcatgatt
     8341 gatgaccaaa atctagagat gtttccaaga gacagtgcta gcctagaaga ggtggaaaat
     8401 cgcatgcgac ttttaaaaga agcctatggt ttcaaggcca ttttccatac cctccgatct
     8461 agtgatgagc aagacaaaaa tgtctatcaa gcctatgctc tggaagaacg atttgaagag
     8521 tctgtccaac taaaaactgc agtctatcaa cgaattggta gcggggatgc ctttatatct
     8581 ggtgcccttt accaactact ccatcattcc tccctaaaaa ctaccattga ctttgcagtt
     8641 gcgagcgcaa ctctcaaatg cactcttcca ggagaccatc tctccacttc cgcaactagt
     8701 attgaaaatt tactggcaaa tgcacaagat atcattcgtt aggagaatta catgaccaaa
     8761 tcagatacga ttattgaact aaaaaaacag aaaattgtcg ctgtcattcg aggaaataca
     8821 aaggaagaag gactacaagc ctcgattgct tgtatcaagg gcggtatcaa agctattgaa
     8881 atcgcctata ccaatcagta tgcaggacaa atcatcaagg aacttgtaga cttgtatcag
     8941 gacgatcaga gtgtttgtat cggtgcaggt actgtgcttg atgccgtaac tgctagagat
     9001 gccattctag ctggagcaaa ttacgttgtt tctccatctt tccatgctga aactgcgaaa
     9061 atgtgcaatc tctacagcac accgtacatt ccaggctgta ttaccctcac agagatcacg
     9121 actgcacttg aagccggtag tgaaatcatc aaactcttcc caggtagtac tctcagtcca
     9181 gcatatatct ctgcagtcaa ggcaccgatc ccacaagttt ccgtaatggt aaccggagga
     9241 gtcggcctaa acaacatccc tcaatggttc gctgctggtg cagatgccgt tggaattggt
     9301 ggcgaactca ataaactcgc ttcccaaggc aactttgacc gcatcagcga gattgcccaa
     9361 cagtatatta cactcagata aaatcataac tacccgtcta acgggtggtt tatcccagag
     9421 ctataagccc aaatcatcag ccagcgccta aagacgctgg cttttacgtt gttcaagcct
     9481 tattgctctt gactcgtcac ttgcctcttt aagagacttt ggtattactt accactatcc
     9541 ctaaagggat cctcatattc ttttacactc aatttatcta gtgctatagt agattgaaac
     9601 tggaatagta tacctctact tctaaaacat tgttaaaaat cgatttgact gtcctgatcg
     9661 attttgtcct gttcttattt cattttacta tatatcatac tttactagtt ctcaaatttt
     9721 catactcgtg aagaaatcat ccactggata atttctttaa tcttgactat atttcttaat
     9781 tgtggcttca ttaagcccta ctggacttac ataataacct tccacccaga aatgccgatt
     9841 cccaaacttg tacttgagat tggcgtgttt gtcaaacatc atgagtgcac tttttccttt
     9901 taaataaccc atgaaactcg aaacacttag ccttagtgga atactgacta acatgtgtac
     9961 atggtctggc attaagtgac cctcgatcat ttcaacacct ttataactac acaagcgatg
    10021 aaatatttcg cctaaactac t
//
LOCUS       DAVAZV010000068         9471 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVAZV010000068 DAVAZV010000000
VERSION     DAVAZV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9471
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.068"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            150..686
                     /locus_tag="VQT46_001875"
     CDS             150..686
                     /locus_tag="VQT46_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET2371845.1"
                     /translation="MKKAHVYAIPAIGAALIAALAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            737..823
                     /locus_tag="VQT46_001876"
                     /pseudo
     CDS             737..823
                     /locus_tag="VQT46_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(892..1107)
                     /locus_tag="VQT46_001877"
     CDS             complement(892..1107)
                     /locus_tag="VQT46_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET2371846.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            1205..1525
                     /locus_tag="VQT46_001878"
     CDS             1205..1525
                     /locus_tag="VQT46_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371847.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(1556..1894)
                     /locus_tag="VQT46_001879"
     CDS             complement(1556..1894)
                     /locus_tag="VQT46_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371848.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQT46_001880"
     CDS             complement(1906..2625)
                     /gene="trmD"
                     /locus_tag="VQT46_001880"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET2371849.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQT46_001881"
     CDS             complement(2615..3133)
                     /gene="rimM"
                     /locus_tag="VQT46_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET2371850.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKRYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(3164..3952)
                     /locus_tag="VQT46_001882"
     CDS             complement(3164..3952)
                     /locus_tag="VQT46_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET2371851.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            complement(4529..4768)
                     /locus_tag="VQT46_001883"
     CDS             complement(4529..4768)
                     /locus_tag="VQT46_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET2371852.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQT46_001884"
     CDS             complement(4788..5060)
                     /gene="rpsP"
                     /locus_tag="VQT46_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET2371853.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            5230..5439
                     /locus_tag="VQT46_001885"
     CDS             5230..5439
                     /locus_tag="VQT46_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371854.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            5918..6139
                     /locus_tag="VQT46_001886"
     CDS             5918..6139
                     /locus_tag="VQT46_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371855.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            6222..7025
                     /locus_tag="VQT46_001887"
     CDS             6222..7025
                     /locus_tag="VQT46_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET2371856.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(7081..8622)
                     /locus_tag="VQT46_001888"
     CDS             complement(7081..8622)
                     /locus_tag="VQT46_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET2371857.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(8624..9106)
                     /locus_tag="VQT46_001889"
     CDS             complement(8624..9106)
                     /locus_tag="VQT46_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET2371858.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(9106..>9471)
                     /locus_tag="VQT46_001890"
     CDS             complement(9106..>9471)
                     /locus_tag="VQT46_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S rRNA methyltransferase"
                     /protein_id="HET2371859.1"
                     /translation="KLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALELAELLKNI
                     KKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGTDIDAACGQ
                     LLFNTMKRDRQKAVAAVNP"
BASE COUNT         2796 a         2028 c         1698 g         2949 t
ORIGIN      
        1 attttcgaat caacaaaaaa attatccaac ttgactagtc acgaaaatcg gctgttacag
       61 tttttgttac cttgttttta aaaaatggtt gacatcgact cctatatgag tataatagtt
      121 atcatacatt agaaaagagg ttaactattt tgaaaaaagc tcacgtttat gctatccctg
      181 ctattggggc tgctctcatt gctgctttgg cacaaatcag tcttccaatt ggacctgttc
      241 ccttcactct gcaaaacttt gcaatcggct tgattgctac tgtctttaga ccgagagagg
      301 ctgtactttc tgctggactc tatcttcttc taggtgctat cggtcttcct gtctttgcag
      361 gaggtggagc tggttttcag gctttagttg gccctactgc aggctatctt tggttttatc
      421 tcgtttactc tggacttact tcctctctaa ccaacagcaa gagtggtgtt gttaagattt
      481 ttcttgcaaa cctcttgggt gatgcccttg tctttgtcgg cgggattctc agcttgcatt
      541 tcctagctgg aatggcattt gaaaaagctc ttgctgtggg ggttcttccc tttatcattc
      601 cagaccttgg caaacttctg gctattagtt ttattagccg tcccctactt caacgcctta
      661 aaaatcaggc ttactttact aactaaaaaa ggatatcgag ttatcatgac tcaatatcct
      721 tttcttttat tttgaaaact tatactcaat gaaaatcaaa gagcaaacta gaaagctagc
      781 cgcaggctgc tcaaaacact gttttgaggt tgtggatgaa actgacgaag tcagtaacca
      841 tacatacggc aaggcaaagc tgacgcggtt tgaagagatt ttcgaagagt attagttgcc
      901 tttaaaggca tccaccatcg tttgaaattc ttcatttgag agagtaatcc ctttgcccat
      961 tttagtatgg tctggactcc aagcacgaat atcaaacttt gcaggggcac cattaaagct
     1021 cacacggtta atttccttgg tccaaccttt ttcgttttca gaaagagtca acaagtgctc
     1081 ttcgatttca aatgtaaatt ctgccatttt cttctccttt tttagtttca ttagtttatt
     1141 cgtaaaatct tgtagatttt aggaaaattt tatataatat tgatataaaa gaagggaggc
     1201 caatatgaga cataaattcc agcaagttct aaataaaata catgattttt taaatggata
     1261 tgaccaacct gaccagactg aaaccaactc ccttacagcc actattgaag aggctatcca
     1321 gaaacaaacc gctgttcacc ttatcttgtc tgagacaagt tttacaggtg atatcatcaa
     1381 atatgatcag caaggccagc aaattatcgt gaaaaatttt gccaaaaatg tgagccggat
     1441 tatccgtata agcgatattc aacgcctgcg atttgtcccc tcaactgtcc aaacagccca
     1501 aaaaaataga tttaagaaag agtgagatgt agttgcttca tcccactctt ttttcttagc
     1561 gaatttgttc aaaatgtaaa tgaactgcaa tatgatctcc ataaccactt ctttccaagt
     1621 cacgttgtaa acgataggaa atgtagtgtt ctgcaatggt aatgtaacct gcgcccaata
     1681 aacgatgttc aaccatagat tgaatcatac tgatagtcgc acgttccacc ttggcttctt
     1741 gtaaatccaa aactaccttc ttagtgactt gagcaagatt ttgacgcaaa tcatctgtca
     1801 aaacataaac agtttgggct gccttcaaga tggcttggta aatcttatct ggattaaatt
     1861 cagcaatttc gccattacgt ttgattactt gcataggttt ctcctttatt ctttgttttc
     1921 tttgatttct gccagcattt tttcttcttc tactgtcagt tgataatgtt caagtaaatc
     1981 cggtctgcgc tcgtaggttt tctttaaact ctcgtacaat cgccactgac gaatcttttc
     2041 atggtggcca ctcatcaata catctggcac gaccatgcct cgataatcat agggacgtgt
     2101 gtactgagga tattctaaaa gacctgaaga aaaactatca tcttggtggc tagactcctt
     2161 gccaatcact tctggaatca ggcgaactgt agcatcaatc atggtcatag ctgccaattc
     2221 tccaccagtg aggacatagt cgcctaggga aatctcatct gttaccaagg tcttaatgcg
     2281 ctcatcataa ccctcatagt gcccacagat aaagattagc tcttcctctt gagccaaatc
     2341 ttcagcataa gcctgatcaa actgctttcc agcaggatcg aggagaataa cgcgcggatt
     2401 tttcttttca atagcatcaa aggaatcgaa aataggttgt gctctgagca acatgccctg
     2461 accgcctccg tagggctcat catctacatg acgggccttt tcagcatttt ctcgaaaatt
     2521 atgatactgg atatccaaga gccctttttc tcgagccttt ccaacgattg agtgctccag
     2581 tggagaaaac atctctggaa agagggttaa aatatcaatc ttcatcgtct aacccttcta
     2641 agatttccac atcgacccgt ttatttggaa tatcaacatt gagaaccact ggtgggatat
     2701 aaggtaaaag caaatcacgt ttgccttttc gtttgaccac ccagacatca ttagcacctg
     2761 gttgcaggat ttccttgatg gttccaacca agctatcacc ctcatagact tccaaaccga
     2821 taatctcgtg atagtaaaat tcaccatcgt ctaggtcatt caaatcttcc tcagcgacct
     2881 tgagactata tctcttgtac ttttcgatag tattgatatg gtacatatct ttgaatttaa
     2941 taatgtcaaa gttcttctgt ttacggtggc tagcgatggt cactgtttgg acaaactgat
     3001 ctttttcatc aaacaaagcc agctcagctc cttttttaaa ccgttcttct gcaaaatccg
     3061 tcacagacaa gactcgcatc tcaccctgta atccctgcgt attaacgatt ttcccaacat
     3121 taaagtagtt catcttgtct cctgtaatct ccttttttcc atcttattct gacaattctc
     3181 gaataatagc cgcaattttt tccgattctg accattgtaa ataatggtga ttccctccta
     3241 aaatgagttt agtattggaa gtccaatatt ctgattctct gtactctttt tctctataag
     3301 gctgacaaaa aacaaataca ggaatatgag cttctataga tacatcctca aaatcttcct
     3361 cagtaatctc tccagatatc tgaaattctg gatcttgatt ttccaactct aagccttttt
     3421 cttgcattaa ttcccagatt tttttattcg tttcaggact aaatgttgct tgagttaagt
     3481 tcttaaaata aagttcagga ccacactcgt caatcagcct catctgctct tccatttctg
     3541 gataaggatt ttctgaaaaa tcagcaaaca tgactttttt agttgtcggt tcaattgcta
     3601 ctaaagtctg acgcttaatt ggtttctcga gtaatttgca agctaaaatt ccactccaac
     3661 tatgtgcaca aagtatatat tcagaaattc ctaattcttc aagtacttca taaaccgcat
     3721 ctgcaagatt atctagattt tttccagctt ggtcatgaat cggactccta cctgtgttcg
     3781 gaaaatcaat tgtcaaataa ccaattgtag gaggaggttt ttcaagtata agtgaaaaat
     3841 tttcataact tggtagcaaa cctgctccgt ttagacaaac tagcactttc ttttgctttt
     3901 gataagtaac agagaggcta ccaatttctg tagatacttc aaacctcttc ataaagaaat
     3961 ccactcattc tatataatga attattaaaa atccttatct tttattttat cacgttccaa
     4021 ggattttctc aagttggagg aaggggacaa catctctact ttcccttcaa aaatccttcc
     4081 aaatcatgtt tatgttggta attaacggct gcggttttgt ctttctcaaa gacagtcttg
     4141 gtaaggtcaa tatgattaat agctacgatt gcgacggtgt agtaaatgat atcagccagt
     4201 tctctggcaa gttcctcgtt cgaatcctat cccttctttt cgaccagagc gcctattcaa
     4261 aacctcggct acttctccga cttcctccac taacttcata aagagacctt catcagtccg
     4321 agactgctgt taatgttcga ttaagtagtc ttggaattgc ctaaacgttc aatcttttat
     4381 agtatattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
     4441 actgtcctga tcgatttgtc ctgttcttgt ttcattttac tatatcttct attccacaca
     4501 aaaaagcgag acatccgtcc cgcccttctt atttttcgtc aataacgatt cttacttttt
     4561 tgtattcagt tgggacagag tagacaatcg ttcttatcgc agaaatagtg cgacccttac
     4621 gaccgattac acgacccaca tcgctttgat caagattcaa atgatattcc aaaaattctg
     4681 gtgtatcctc aatcttgata gttaaggcat ctggttgtga aattaagggt ttcacaatcg
     4741 caataatgag attttcaatc gtatccatct gtcaacctac tttaaactta ttttgaaaat
     4801 ttagaatcgt ggaatttttt caatacgcct tcttttgaaa ggatgttacg tactgtgtct
     4861 gaaggttgag ctccattagc caaccatgca agaacgcggt cttctttcaa agttacttgg
     4921 ttttcagcaa caagtgggtt gtaagttcca actgtttcga tgaaacgtcc gtcacgtggt
     4981 gaacgtgaat ctgctacgtt gatacggtag aaaggttttt tcttagaacc catacgagtc
     5041 aaacggattt taactgccat ttttaaagtc tcatttcttt aattttttat ttcggtgaaa
     5101 tagctgagct atttagcaca tgttctatta tagcagattt ctggcatgtg tcaagaaaaa
     5161 aacttgacag actataaatt tcttaaagta tttagaaatt tgttagaata ggaaataaat
     5221 gtttgaaaga tgctatccgt gaatactatt ttagaaaaat tttataaaga acaccaagtc
     5281 aaacccttca tatcgcctga acgagagttg gatacttggc ttctaagtcc caagcccgtt
     5341 cccaagcgaa atatggactt attagtagat gattcactag caggagatat cattttacta
     5401 tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact cccattcgaa
     5461 tatgattcaa aattcgctta gaatcaatgt tttcccgctt tttcaaaaaa taaattttca
     5521 tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta aaaagcaccc
     5581 catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt agcgtttaga
     5641 gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt tgagtacact
     5701 tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta tgctcttgtc
     5761 gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa tatcctgaag
     5821 aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca agcccttcat
     5881 gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg gactttttta
     5941 caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa actttattgc
     6001 agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac taagttcttt
     6061 tcagaaacca tttactgggg aagaagttga agaagttgaa gattttcaag atgatgatga
     6121 aatcccaact attatctaag ccagttctgt aaactactaa tatttgaaat ccacttcttt
     6181 ttagggtaca atggtataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
     6241 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
     6301 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
     6361 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
     6421 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
     6481 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
     6541 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
     6601 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
     6661 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgtggtg
     6721 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
     6781 aaagctctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
     6841 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggtcaag
     6901 tgattgacgg tatggatgtt gtggataaga ttgctaaggc cgaaaaagat gaaaaagaca
     6961 agccaactac tgctatcaca atcgacagca tcgaagtggt gaaagactac gattttaaat
     7021 cttaaaaacc aaaaaaatac agtatccaca ttcggtactg tatttctttt actctcattc
     7081 ttaagttaaa ttattaaaat cccatatttg gtctatccag ccttcataaa agtctggctc
     7141 gtggcagacc ataaggatag atcccctata ttctttgaga gcgcgtttga gctcatcctt
     7201 tgcatccaca tccaaatggt tggtcggctc gtccagcact aaaacgttgt tttcacgatt
     7261 catcaagaga cagaaacgaa ccttggcttg ctctccccct gataatactt gaatctggct
     7321 ttcaatatgt ttggttgtca aaccacaacg ggcaagggct gcacggactt ctgcttgatt
     7381 aagggcagga aaggcattcc agacagcttc aagaggagtt tggcgattac cgccttctac
     7441 ttcctgctca aaataaccaa gttctaaata atctccacgc tccacttccc cagcgattgg
     7501 cgagataatg cccaagagac tcttcaagag agttgttttt ccaataccat tagcaccaat
     7561 aatcgcaacc ttttgattgc gttcgaaggt aagatttaaa ggcttagtaa gaggaaggtc
     7621 gtaaccaatt tgcaagttct tggcttggaa gataaagcgc cctggtgtac gagctggttt
     7681 gaaatcaaag gatggttttg gtttctcact ttggagttcg ataatatcca tcttatccaa
     7741 tttcttttga cgagacatag ccatattacg agttgcaaca cgggctttat tacgagccac
     7801 aaagtccttg aggtctgcaa tctctttctg ctggcgttcg taggctgcct ctagctgaga
     7861 tttcttcata gcataaactt cttggaactg gtagtagtca ccagagtaac gcgtcagctg
     7921 ttgattttcc acatgataga caatattgat aacgtcattg aggaatggaa tatcgtgcga
     7981 aatgagaaca aaggcattct catagttttg gagatagcgc ttgagccaat caatatgctc
     8041 agcatccaag tagttggtcg gctcgtccaa cagcaagata tcaggctttt caaggagaag
     8101 ttttgccaaa agcaccttgg ttctttgccc acctgacaaa gaagttacat ccgtatccat
     8161 gccaaagtcc ataacaccaa gagcacgcgc tacttcgtca atcttagcat ccaaggtata
     8221 gaaatcacga ctctccagac ggtcttgaag ttctcctact tcttccatga gagcatcaac
     8281 atccgcaccg tcttcagcca tttccatata gaggtcattg atacgagctt cagctttgaa
     8341 aagctcatca aaagccgtac ggagaacatc acgcaccgac tgtctttcag caaggacaga
     8401 gtgctgatcc aagtaaccag ccgtcacata tttggaccac tcaacctttc cttcatctgg
     8461 cagcatttta ccagtcacga tactcataaa ggttgatttt ccttcaccat tggcaccgac
     8521 caggccgata tgttctccct tgaggagacg gaaggacaca tcttcaaaaa ttgcacggtc
     8581 accaaaaccg tgactcagat ttttaacttc taaaatactc attttaattc cttatcttgt
     8641 ttttatgtaa tcgtttataa aggagccaag ccagatagcc acccaaagtg ttggtccaca
     8701 aatcatcaat ctcaaagacg cgattgaaat caaagaaaaa gtccaagatt aattgcgtac
     8761 actcgattcc aagactcaca agaaaactaa aaagaaggac cttttttgtt ttccgcaaat
     8821 ttggaaatag ataaaggagt tggaaaatca gaggaaaaaa caagaagaca ttgaggatat
     8881 tttgtaaaaa aatccaacat aattgtccaa tgtcactcac ttcgcccagt ttccagagag
     8941 aattgaaagg agtcaaaaga aaaaccaggc gtccaagatg ctgaatatct ggagttccca
     9001 ctcccacggt agattgttct tgaggagtaa agcaaaaata gacaatgcaa atgctataga
     9061 aaatgactcc ccagaccaaa atatgattat aagtcttctt catcattaag gatttaccgc
     9121 tgcgactgcc ttctggcggt cacgtttcat tgtgttaaag agcaattgtc cacaagctgc
     9181 gtcaatatct gtaccatgct cttgacgaac cacacagttg cccccttttt tcttaagcgt
     9241 atcatagaaa gccaacacgc gctctttggg actacggcta tattggtcat gctcactaac
     9301 tgggttataa ggaatcaagt ttacataaga cgatttcttg atgttcttga gcaattcagc
     9361 caattccaag gcttgttcca caccgtcgtt gacttcatta agcatgatat attcaaaggt
     9421 tacacgacgg tttgttgtct caatgtagta ttcaatagca gcaaagagtt t
//
LOCUS       DAVAZV010000069         9149 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVAZV010000069 DAVAZV010000000
VERSION     DAVAZV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9149
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.069"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQT46_001891"
     CDS             226..6657
                     /locus_tag="VQT46_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET2371860.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VVDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARIKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPYGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANHADEKG
                     MISYYLVDPDKDASKYEKLGEISEDKLKNAKSPEENTNNNQAKDEDSKPDEKSSVEGE
                     ASLEINKTISTIREFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIAY
                     DDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6948..7294)
                     /locus_tag="VQT46_001892"
                     /pseudo
     CDS             complement(6948..7294)
                     /locus_tag="VQT46_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7389..7574)
                     /locus_tag="VQT46_001893"
                     /pseudo
     CDS             complement(7389..7574)
                     /locus_tag="VQT46_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7602..7829
                     /locus_tag="VQT46_001894"
     CDS             7602..7829
                     /locus_tag="VQT46_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371861.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7905..8457
                     /locus_tag="VQT46_001895"
                     /pseudo
     CDS             7905..8457
                     /locus_tag="VQT46_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            9040..>9149
                     /locus_tag="VQT46_001896"
     CDS             9040..>9149
                     /locus_tag="VQT46_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HET2371862.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIV"
BASE COUNT         3433 a         1311 c         1791 g         2614 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttaaataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taaccacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaaacatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa catgaagata ttcataatgc tatagaaact
      421 tcacaggatt ttaaagagaa gaaaacagca gtcattgagg gaaaagaagt tgttagtaaa
      481 aatcctgtga cagacaataa cactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagatcatac ggactcattt gtgaataaaa acacagaaaa tcccaaaaaa
      601 gaagataaag ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagcaactat ccaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccgtttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttcgggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgaag atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccatatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgataaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcat gctgatgaaa aggggatgat ttcttattac
     4201 ctagtagatc ctgacaaaga tgcttctaaa tatgaaaaac ttggtgaaat ttctgaagat
     4261 aaactcaaaa atgcaaagag cccagaggaa aataccaata ataatcaagc taaggatgaa
     4321 gattcaaaac cagatgaaaa aagttcagtt gagggagaag ctagccttga aataaataaa
     4381 actatttcaa caattagaga gtttgaaaat aaagacctaa agaaactcat taaaaagaaa
     4441 tttagagaag ttgatgattt tacaagtgaa actggtaaga gaatagagga atacgattat
     4501 aaatacgatg ataagggaaa tattattgct tatgacgatg gtagtgcctt acaatatgaa
     4561 actgaaaaac ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaatagct ataaatcgat agaaatcaaa gcgactaagt atgattcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa gattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccctatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga tctttcaaag aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagac
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa cagccattta taactcaatt atttagttta cttcactatt gatactattt
     6781 ggagttatta atggacttag tttagataac taatgaattg attgaaaggg ttagtattga
     6841 caatattggt catattgatt agaaaataga gtctatcaaa atttaaaggc taatagaggt
     6901 gatgagacaa tttcggctct ttgtcaactg tagtgggttg aagtcagcta agctcgagaa
     6961 aggacaaatt ttgtcctttc ttttttgata ttcagagcga tgaaaatccg ttttttgaag
     7021 ttttcaaagt ttcgaaaacc aaaggcattg cgcttgataa gtttgatgag attattggtc
     7081 gcttccagtt tggcattaga atagtgtagt tgaagggcat tgacaatctt ctctttatct
     7141 ttgaggaagg ttttagagga tgaacctgat tcagattgtc ctcaatgagt ccgaaaaatt
     7201 tgtcaggctc cttattctga aagtgaaaaa gcaagagttg atagagatta tagtggtgtt
     7261 tcaagtcttc tgaatagctc aaaagtttat ctatagtaga ttgaaactag aatagtacac
     7321 ctctgcttct aaaacattgt tagaaatcga tttgactgtc ctgaatgatt tgtcctgtta
     7381 ttatttcatt ttactataaa tccacgttta cgaatctctt tccacacttg ttcaatgggg
     7441 ttcatctctg gtgtgtatgg aggaataaat gcaaaaccaa tattagtcgg aatctttaag
     7501 gtacttgatt tatgccatat agcattgtcc ataacgagta aaagataatc atctggataa
     7561 gcttgtgaaa gctcctattc ctaaagcccc tttataacct cttgcgagag agactattga
     7621 ctcagccctt acttcatgcg gatgaaactt cttatcgggt tctagagagt catagccatc
     7681 tgacctacta ttggaccttt ttgtctggga aagttgagaa tcaagcaatc acgctgtacc
     7741 atcatgatca gagtcggagt ggttcggtag tacaagaatt cctaggagat tattctggct
     7801 atgttcattg tgatatgttg cggcagtaac ttaggacttt agtcctctag ttctgcctat
     7861 gcgatagcag tccaaggttt aggagcaagg cgacgctaag cttggtaaac tgcgaactgc
     7921 tagaagctta tcgtcaactg gaagaagctg aacttgttgg atgttgggcg catgtgagaa
     7981 ggaaattttt tgaagcgacc cccaagcaag cagataaatc atccttagga gctaaaggtt
     8041 tagcttattg tgatcagtta ttttccttgg aaagagactg ggaggctttg ccagctgatg
     8101 aacgactaca gaaacgtcaa gaacatctcc agcccctaat ggaagacttc tttgcttggt
     8161 gccgccgtca gtcagtttta gcaggttcaa aactaggaag ggcaattgaa tacagcctca
     8221 agtatgaaga aacctttaag actattttga aagacggaca tctggtcctt tccaataatc
     8281 tagctgaacg cgccattaaa tcattggtta tgggacggag taaaagagtc cagtggactc
     8341 ttttagcctg agctcagttt aaaaaagcga gggtggttat tttctcaaag ttttgaagga
     8401 gctaaagcaa gagctattat tatgagcttg ttggaaacag ctaaacgtca tcaattatag
     8461 tgcgttgaat ctataacagt acgcatcgac tgctaaaaca tttctataaa tcaattttcc
     8521 tttcctaatc gatttgttca tatcttattt caatccatta taaatagcga gaaatatcta
     8581 tcctatcttc tagaatgtct tccaaacgag gaaactctcg taaacaaaga ggttttagag
     8641 gcctatttac catggactaa agttgtacaa gaaaagtgca aataagaaat ctccagatta
     8701 ggaactatcc gtgagttcac taatctggag atttttcaat agacttcgtt attgggcggt
     8761 tacgatatga tcactgactt cgtcagtctt atctacaacc tcaaaactgt gttttgagca
     8821 acctgcggct agcttcctag tttgctcttt gattttcatt gagtattaga acagaaaaaa
     8881 tacttggagt atttgtttgt gtgtttattt ttatataaca aactataaac aaaacaaaaa
     8941 tataaaaaaa gagacaaaaa agaacagaaa gcaattgaca acggtttcat atagtgttat
     9001 acttatggca taaagttaat ggaaagaagg gaaaaactta tggtattaga ttatttcttt
     9061 gacaaaaacc ttgtgttttg cttagaagcg gataatcaag aacaactctt tgatcaggtt
     9121 gcaactttat tggaagaacg agaaattgt
//
LOCUS       DAVAZV010000070         9136 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVAZV010000070 DAVAZV010000000
VERSION     DAVAZV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9136)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9136)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9136
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.070"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..294
                     /locus_tag="VQT46_001897"
                     /pseudo
     CDS             1..294
                     /locus_tag="VQT46_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            370..819
                     /locus_tag="VQT46_001898"
     CDS             370..819
                     /locus_tag="VQT46_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000337416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET2371863.1"
                     /translation="MCTILVSIYYKIGLSSSGVYKAVADGEMTVSLSYEDPAVKLLND
                     GANIKVVYPKEGTVFLPASAAIVKKSKNMENAKKFIDFIISQEVQDTLGTTTTNRPVR
                     KNAKTSENMKPIDKIKTLTEDYDYVIKNKSDIVKKYNEVFTDIQSKQ"
     gene            832..1491
                     /locus_tag="VQT46_001899"
     CDS             832..1491
                     /locus_tag="VQT46_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371864.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIEGGEFYFDDTKINNMEPSKRNIGMVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYADRKPDKLSGGQQQRVTLACALAVNPSVLLMDEP
                     LSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAISDQIAVMKDGVIQQIGRP
                     K"
     gene            1618..1923
                     /locus_tag="VQT46_001900"
                     /pseudo
     CDS             1618..1923
                     /locus_tag="VQT46_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809465.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
     gene            1913..3558
                     /locus_tag="VQT46_001901"
                     /pseudo
     CDS             1913..3558
                     /locus_tag="VQT46_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(3661..4353)
                     /locus_tag="VQT46_001902"
     CDS             complement(3661..4353)
                     /locus_tag="VQT46_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2371865.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEMIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGCEKMEEGSI"
     gene            complement(4597..5934)
                     /locus_tag="VQT46_001903"
     CDS             complement(4597..5934)
                     /locus_tag="VQT46_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET2371866.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALTETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGAAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     IGDSVARVLEEMGLETVGTHGTTVALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(5944..6210)
                     /locus_tag="VQT46_001904"
     CDS             complement(5944..6210)
                     /locus_tag="VQT46_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET2371867.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQT46_001905"
     CDS             complement(6475..6861)
                     /gene="rplQ"
                     /locus_tag="VQT46_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET2371868.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(6873..7808)
                     /locus_tag="VQT46_001906"
     CDS             complement(6873..7808)
                     /locus_tag="VQT46_001906"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET2371869.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQT46_001907"
     CDS             complement(7851..8234)
                     /gene="rpsK"
                     /locus_tag="VQT46_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET2371870.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQT46_001908"
     CDS             complement(8252..8617)
                     /gene="rpsM"
                     /locus_tag="VQT46_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET2371871.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQT46_001909"
     CDS             complement(8635..8751)
                     /gene="rpmJ"
                     /locus_tag="VQT46_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET2371872.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQT46_001910"
     CDS             complement(8776..8994)
                     /gene="infA"
                     /locus_tag="VQT46_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET2371873.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
BASE COUNT         2766 a         2044 c         1567 g         2759 t
ORIGIN      
        1 tcaaaagaaa atgataatgt tatcaaagaa tatcaaaaca caactggctt ctctactcct
       61 tatacactag atggtagtgt tttaatcgtc caccctgatt taactaaagg catgaacatc
      121 gaaggatata gcgaccttct caaacctgaa ctaaaaggaa aaatcgcaac tgctgaccca
      181 gcaaactctt ctagcgcctt tgctcaatta acaaatatgc tacaagctca aggtggttac
      241 aaagatgata aggcttggtc ttatgtaaaa gatcttttca cacttattga tggtatagta
      301 aaatgaaata agaacaggac aaattaatca ggacagtcaa atcgatttct aacaatgttt
      361 tagaagtaga tgtgtactat tctagtttca atatactata aaatcggttt aagttcatct
      421 ggtgtctata aagcagtcgc tgatggagaa atgactgtta gtctctctta tgaagatcca
      481 gcagttaaac tcttaaatga cggagctaac attaaggtag tctatccaaa agaaggaacc
      541 gtcttcctac ctgctagtgc tgctatcgtt aaaaaatcta aaaatatgga aaatgccaag
      601 aaatttatcg attttattat ctctcaagaa gtacaagata cacttggtac aaccactact
      661 aaccgtcctg ttcgtaaaaa tgctaaaaca agcgaaaaca tgaaaccaat tgacaaaatc
      721 aaaacactca ctgaagatta tgattatgtc atcaagaata aatcagatat cgttaagaaa
      781 tacaacgaag tctttacaga tatccaatct aaacagtaaa agaggttcac tatgagtgag
      841 atcgaaatta ttaacgccaa aaaaatctac cacgatgtcc ctgttattga gaatttgaac
      901 attacaattc caaaaggaag tctctttacc cttcttggag cttcaggatg tgggaaaacg
      961 acccttcttc gtatgattgc aggtttcaac agtatcgaag gtggagaatt ttacttcgat
     1021 gatacaaaaa tcaataatat ggaacccagc aaacgcaata tcgggatggt tttccaaaac
     1081 tacgctattt tcccacattt gactgtccga gacaacgttg cttttggtct tatgcaaaag
     1141 aaggttccaa aagaagaatt gattcaacag accaacaagt atcttgaact catgcaaatt
     1201 gctcaatatg cggatcgaaa gcccgataaa ctcagtggtg gacaacaaca acgtgtcacc
     1261 ttggcatgcg ccttagcggt taatccaagt gttctcctca tggacgagcc acttagtaat
     1321 ctggaggcca aacttcgctt ggatatgcgt caagccatcc gagaaatcca acacgaagtg
     1381 ggaattacaa ctgtttatgt aacccacgac caagaagaag ccatggctat ttcagaccaa
     1441 attgctgtta tgaaagatgg ggtgatccaa caaatcggcc gaccaaaata actctatcat
     1501 aaaccagcta atgagtttgt ggcaaccttt atcggacgca caaatattat ccctgccaat
     1561 cttgaaaaac ggagcgacgg cgcttatatc gtcttttcag atggctatgc ccttcgaatg
     1621 ccagctcttg atcaggttga ggagcaagct attcatgtaa gcattcgtcc cgaagagttt
     1681 atcaaagatg aatctggaga tatcgaagga actattagcg atagcgtcta tcttggacta
     1741 aatacggagt atttcattga gacaggtttt gcctcaaaaa tttaagttag tgaagaatca
     1801 acttttgaag aagaactaca aaaaggcaat cgtattcgtc tacgaatcaa tacgcaaaaa
     1861 ttaaacatct tttctgcaga tggttcccaa aacctgataa aaggagtcaa ccatggaatg
     1921 taaaaaacta aatatttgga cagcttcctc tttcttcatc tttcttacct atcttgtctt
     1981 tctcgtttat cctatcgtta ccgtgctcaa gcaagcactt atacatgaag gacaattctc
     2041 actagctaat tttgtcactt tctttagtaa agcctactac tctgagacac tagtcaacag
     2101 tttcaaggtt tccattaccg ctactatcac ttccttagtt gtaggaaccc tattagctta
     2161 tctcttctct atgtatgact tcaaggggaa gaaatttcta caaatattga ttatcattgc
     2221 ttccatgtca gctcctttcg taggagccta ctcctgaatt ctcttgctgg gacgaaatga
     2281 ggtcatcact aaatttttga caaatgccct tcatcttcca gctatcgata tttatggatt
     2341 caaaggaatt gtacttgtct ttacactgca actattccca ctggtatttc tatatgttgc
     2401 tggaacaatg aacagtattg acaattctct acttgaagca gctgaaagca tggggtcctt
     2461 cggatttaag cgtatcgtaa cggttgtttt acctctccta gttccaacct tactagcagc
     2521 tccttgcttg tatttatgag agcattctca gactttggaa cgcctatgtt gattgacgaa
     2581 ggatatcgga ctttccctgt cctgatttat acccaattta ttagcgaggt tggaggaaat
     2641 tctgcttttg caattatggc gattatcatt gccttggcaa ttttccttat ccaaaaacac
     2701 attgcaaacc gctacagttt cagcatgaat ctgctccatc caattgagcc taaaaaaact
     2761 acaaaaggaa aaatagctgc catttatgca acagtctacg gaattatctt tatctctgtt
     2821 ttacctcaaa tctacttaat ttatacctct ttcctaaaaa catcaggtat ggtatctgtt
     2881 aaaggttatt ctccaaacag ttacaaggta gctttcaatc gtatgggatc tgctattttc
     2941 aataccattc gtatcccttt gattgcctta gttctagttg ttctatttgc gacatttatc
     3001 tcctacctag ccgttagaaa acggaatttg tttacaaact taattgacag cctcagtatg
     3061 gtaccttata ttgtaccagg aaccgttcta gggattgcct tcatttcttc cttcaatact
     3121 ggtctatttg gaagtggatt tcttatgatt acagggactg ctttcatctt gattatgtct
     3181 ctatctgtca gaagattacc ttatactatt cgctcatctg ttgctagctt acaacaaata
     3241 gcaccaagta ttgaagaagc tgctgaaagc ttaggaagta gtcgtctcaa tacctttgct
     3301 aagattacaa ctccaatgat gctatctggt atcatttctg gagccatctt atcttgggtc
     3361 acaatgattt caaaactctc tacttctatc ctcctctaca atgtcaaaac aagaacaatg
     3421 actgtagcta tttatacaga ggttctcaga ggaaattacg gtgtagccgc agccttgtca
     3481 actatcctga ctgttctaac agtaggttcc ttgctcttgt ttatgaaaat ctctaaaagc
     3541 aatagcatta cactttagtt ttccacatca aaaacagccg aaaggagtgc cctcggctgt
     3601 tttttcttat cttgatattc ttatcaaatc cctagctcat ggcaagcaag tctagactga
     3661 ttaaatagag ccttcttcca tcttctcaca tcctagctct cggtaactac ggtcaccgac
     3721 aacttcaacc ctaaactgac cgtcctcata ttcaagaatc gtcacgctac cattatctag
     3781 accatgcgga tgcatgccat taatcagata aacaatggtt ccaatagtca ttccatggct
     3841 gacaacaagg gcgttacctc caccttgatc ttccatttct tttgcaatca tttcaaagcc
     3901 ttccttgatt cggccactga gtttttccca gccttcagcc caaccagctg tatcgacctc
     3961 taccaagccc tcagccagtt cagcataaga caattggtga acgtggtcca cattaaagat
     4021 acgaggaata atgcccatga aaagatcgcc atcataggct ccatcaaaac taccgaaaca
     4081 ccattctctg atacgcttgt ccatgcgata agggattttc ccctgcaagc caagttcttc
     4141 aaggataatt cccatggtct gaatggtacg accagaatca ctcgaataag cgcgctcaaa
     4201 ctgtagatca gattctcgca aaccgattcc taactcttga atccctcgtt caccttcagc
     4261 agttaaggga gtatcgctcc aaccttgcgc gcgaccaatc gtgttaaaca tggtcttgcc
     4321 atgacgtacc aaatacaatc gtacttttac cattttccgt cctccgtttg cttctattat
     4381 atcatgaatg ataaaataaa agccacccat acaggcgact tttgaaggag attattatga
     4441 aaaagtttag gagttcatta aataaagata ttagatgaaa atcaaattca aactaattca
     4501 gtgttatctg tttcaaataa tattaggagg tctttattta atgattatag tatacacatc
     4561 taatcttaaa tagaacttaa aatttctcct attttcttaa tttttaaaac tatgaattgg
     4621 tgctgggatt tgtccaccgc gagagatgaa gtcgacagac gaagccccat taaccttcat
     4681 aacaggtgca gttcctaata gaccaccaaa ctcaatcata tcgccttctc ttcctttggg
     4741 aatgatacga acagctgttg ttttcatgtt gataacaccg attgctgctt catccgcaat
     4801 catagccgca atggtttcag caggcgtatc ttctgggatg gcaatcatat ccaatccaac
     4861 agaacagata gccgtcatag cttctagttt ttctaaatta agagagccat tttgcactgc
     4921 agcaatcatt ccttcatcct cagaaacagg gataaaggcg ccagataaac caccgacttg
     4981 gttgcaggcc atcactccac cctttttaac ttggtcgttc aagagggcca aggcaaccgt
     5041 cgttccatgc gtgccaactg tttctagccc catttcctca aggacacgtg ccacagagtc
     5101 tccaatcgca ggggttggtg ccaaactcaa gtccacaata ccaaactcca cacccagtct
     5161 ctcactggcc atttgaccaa ccaattgacc gatacgagtg attttaaagg cagttttctt
     5221 aactgtttcg gctactacat caaagctctg tccacgaact ttttccaaag cacgtttcac
     5281 cacaccagga ccagaaactc cgacattgat gataacatct gcttccccaa caccatgaaa
     5341 ggcacccgcc ataaatggat tgtcctcaac agcattagcg aatacaacca acttagccgc
     5401 tcccatatct gaaagatttg ccgtttcctt gataattcgt cccatatctg ccacagccgt
     5461 catattaata ccagacttgg ttgagccgat attgactgac gagcagacct tatccgtctc
     5521 agtcaaagcg cgaggaatgg aattgatgag aatctcatct cccttttgat aacctttttg
     5581 tactaaggca gaaaaaccac caataaagtc cacaccaatc tctttcgcag ccttatcaag
     5641 cgcttttgcc agaaccacgt agtccgtcgc atctgtcgct gccccaatca gagaaatagg
     5701 tgtcaccgat acacgcttat taacgatagg aattcccaac tcagccgcaa tttcatcacc
     5761 aacagctact aaattagccg cctttgtcgt aattttttga tagattttct ccgcagcacg
     5821 attgatatct ggatcgatac agtccaaaag agaaatcccc atggtaatgg ttctaatatc
     5881 gaagttttgc tcctcaatca tggcgatggt ttcagtaact tgtctaatat ccatgatgac
     5941 ctcctagata ttatacatag cttcgaaaat cgctgcactc tgaatattga tttttacatt
     6001 caaagtttgc ccaaaagctt caaattcatt acgaagatag gtaaaatctt gcttttcatc
     6061 actagataca acagccatca tcgtaaaata ttcatccaag acagtttgag agatatcgtc
     6121 aatattcaat cctaattctg caattttacc agaaacacct gcaacaattc cagatttatc
     6181 tttaccaaca acagttataa tggctttcat aagtaaactc caattcttct taaaataaga
     6241 aaccttaaca ttaaacagga ttcttttcaa atagtatagc ataattctaa cgaaaatact
     6301 caaaaacgcc tgcttacgaa gttgttctta agaaaaaaac aatttcgtaa acaagcgtct
     6361 actatcccaa cttatgatga gtgttcccgc taggaccgaa atcctagcgg tagaccagag
     6421 ctagactaag agcacaagac tccatcatca taacactcaa caaaattgat gattttatac
     6481 taattcgatg atcgccattg gcgctgcatc accacgacgt ggttcagttt taaggatacg
     6541 agtgtatcca ccgttacgtt cagcataacg aggtgcgatt tctgagaaca atttttgaag
     6601 tgctgtagta gaagtgtact tatcagttgc ttcatcatag ttttcagatg cgatttcatt
     6661 acgtacgaaa gcagctgctt gacgacgtgc atgcaaatca ccacgtttac ctagagtaat
     6721 cattttttca acagttttac ggatttcttt agcacgagct tcagttgtca cgattgattc
     6781 gttgatcaaa aggtcagttg tcaaatcgcg aagcattgct ttacgttgtg agctagtgcg
     6841 tcctagttta cggtaagcca tgtattcctc ctttatttat cttttaatcc aagacccaaa
     6901 tcaatgagtt tgagtttcac ttcttccaaa ctcttgcgtc caagatttcg tactttcatc
     6961 atctctgctt cagatttttc tgtcaaatca tgcacagtat tgataccggc acgttttaaa
     7021 cagttgtatg aacgcacaga caagtccagt tcctcaatcg tacgatctaa aatacggtcg
     7081 tcagattcag tatcagcttc tttcatcact tcagttgact tagcaatctc agtaagattt
     7141 gtaaacaaat caagatgttc tgtcaaaata cgtgctgaaa gccctaaagc atcttctgga
     7201 ataattgttc catttgtcaa gatttcaagg gttaatttgt cgaaaccatc attgctacct
     7261 acacgagcag gttccacttg atagttgact tttgtaactg gtgtataaat agaatctaca
     7321 gcaagtgttc caactggtgc attatccttt ttattttcat cagcaggtac atatccacga
     7381 ccactgttaa cagtcatagt cgcttttaga gaagaacctt caccaattgt aaagagataa
     7441 tgatctggat ttacaatttc aatatcgcta tctgtcaaaa tgtcaccagc tgttacttca
     7501 gcaggacctt caacatccag ttcgatgatt ttttcgtctt caacgtacga tttcactgca
     7561 attcctttaa tgttcagaat gatttgcatc acgtcttcac gaacacctgg aactgtgtca
     7621 aactcatgta acacaccatc aatgttgata gatgtcacag ctgctcctgg tagagaagct
     7681 agaagtacac gacgaagaga gttaccaaga gttgtaccgt agccacgttc aagtggttcg
     7741 attacaaact tgccataatc tttattttca tcaatttttg ttatatttgg tttttcaaac
     7801 tcgatcattt agttactccc tcttaaacga aaagcagtgt aatgcgatga ttatacacgg
     7861 cgacgttttg gaggacgagc accattgtgt ggcactggag tcacatcacg aattgctgtt
     7921 acttcaagac cagcggcagc aagcgcacga atagctgact cacgaccaga acctggacct
     7981 tttacagtaa cttcaactga tttaagaccg tgttcttgtg cagatttagc agcagcttca
     8041 gaagccattt gagcagcgaa tggtgtagat ttacgagaac ctttgaaacc aagagcacca
     8101 gctgatgacc aagcaattgc attaccatgc acatcagtaa tcataacaat agtgttatta
     8161 aatgtagcgt gaatatgagc aataccagat tcgatattct ttttcacacg acgtttacgt
     8221 gttggtttag ccaagacttt tacctcctat attatttttt cttaccagca atcgcaacag
     8281 ctttaccttt acgagtgcga gcgttgtttt tagtattttg tccacggaca ggaagtccac
     8341 gacggtgacg gataccacgg tatgaaccga tttccatcaa acgtttgatg ttcaagttta
     8401 cttcacgacg aaggtcacct tcaactttga ttgcatccac ttcacgacgg atagcatctt
     8461 cttgatctga tgtaagatca cgtacacgaa catcttctga gattccagca gcagccaaaa
     8521 ttttcttaga tgttgcaagt ccgataccat aaacataagt caatgagatt actacgcgtt
     8581 tgtcatttgg aatatcaact ccagcaatac gagccatgtt ttctcctttc tatcttatcc
     8641 ttgacgttgt ttgtgttttg gatttgctgg gcaaattacc ataacacgac cattacgacg
     8701 aataacttta cagtattcgc aaattggttt gaccgatggt cttactttca tttcttatcc
     8761 ctccaagttt ttcgattatt taaagcggta agtgatacgt ccacgtgtca agtcatatgg
     8821 actcatttcg acagtaacac gatctcccgc taaaatacga atatagtttt tacgaatttt
     8881 accagaaact gttgctaaaa tctgatgtcc attttcaagt tcaaccgtaa acattgcatt
     8941 cggcattgta tcaactactt tgccttcaac ttcaatcaca tcgtcttttg ccacgcaaaa
     9001 gcacctccat aaatttcgat tcgatgcctc tagacacaga gacaacaatt ataagtcaga
     9061 ctatctcagt ataacatttg tagcggattt ttgcaagtgc gaaaaacgct ttatttcaaa
     9121 tttgtcaata cttttt
//
LOCUS       DAVAZV010000071         8676 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVAZV010000071 DAVAZV010000000
VERSION     DAVAZV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.071"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            264..1322
                     /locus_tag="VQT46_001911"
     CDS             264..1322
                     /locus_tag="VQT46_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371874.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFIFSYILLFAQ
                     SYLGGNTVWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFDGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKG"
     gene            1637..2611
                     /locus_tag="VQT46_001912"
     CDS             1637..2611
                     /locus_tag="VQT46_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371875.1"
                     /translation="MKNKRYFFDTILMILLLISTIFCVSPVFIKLDILGTPSHAILTF
                     VLAIPLFYILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFS
                     PGIAVFYKESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQ
                     KLYRIENQQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIK
                     PYLSESVREQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLKKIL
                     EVRPDFVLIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSTK"
     gene            2991..3365
                     /locus_tag="VQT46_001913"
     CDS             2991..3365
                     /locus_tag="VQT46_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET2371876.1"
                     /translation="MELVLPNNYVVLEQEEMMYLDGGFSIPRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            3573..4475
                     /locus_tag="VQT46_001914"
     CDS             3573..4475
                     /locus_tag="VQT46_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371877.1"
                     /translation="MIRKLIVFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEGLIKIFPFIFIRRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESNLHKILMDKIQKSELSYSDLMSLLLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            4531..4770
                     /locus_tag="VQT46_001915"
     CDS             4531..4770
                     /locus_tag="VQT46_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET2371878.1"
                     /translation="MELVLPNNYVVIDEEVMMYLDGGAYLSKRACQGICAAAGVLATA
                     AGKIAYCIGYGVLNRGCDINENPYPWDGFISATVR"
     gene            4767..5495
                     /locus_tag="VQT46_001916"
     CDS             4767..5495
                     /locus_tag="VQT46_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371879.1"
                     /translation="MSNVDKIRKIHIIVCWVYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLVINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGKVDNHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            6630..6869
                     /locus_tag="VQT46_001917"
     CDS             6630..6869
                     /locus_tag="VQT46_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371880.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQDGVFILEDFRNILCTMM"
     gene            7419..>8676
                     /locus_tag="VQT46_001918"
     CDS             7419..>8676
                     /locus_tag="VQT46_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET2371881.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAVKKYEAAKKEYEDGKAAQKKYEDDQKKTEEKAEEERKASEEEQAANLKYQQEL
                     VKYIRENDPTKKAEAKKAMDEAEKEYKKKQTEFAEVRAKVIPSAEELKKTRQKAEEAK
                     AKEAELTKKVEEAEKKVTEAKQKVDAEHAEEVAPQAKIAELEHEVQKLEKALKEIDES
                     DSEDYVKEGLRAPLQFELDVKQAKLSKLEELSDKIDELDAEIAKLEKDVEDFKNSDGE
                     QAGQYLAAAEEDLVAKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPEKPAEEPENPAPAPQPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAEKPAPA
                     PQPGWKQENGMWYFYNTDGSMATGWLQ"
BASE COUNT         3004 a         1177 c         1582 g         2913 t
ORIGIN      
        1 taaatctaat aaattctatt attatagctc ttggtatgat attggcatta attttggtat
       61 tatcaagagt gtatagaaaa tatttttata gagacgatga tgactaaagt ttttatcaat
      121 aatttgggct ccttgtcaac tgtagtggat tgaagaaaag ctaacgtctg gggaagggtt
      181 taaagctttg ctttatcaaa tattgactta cagagttgct ctattgtatt gatgtattct
      241 tagtaaataa tatggtgttt tgaatgaaag atgatcagaa atatttatta gcgggacttt
      301 attcgcttct agttgcaata ttttattttc cattgattga gtccaagggg atttttgtaa
      361 gtatattgat ggcggtttta cttttatatt taatatactt cattgcaaca gtcattcata
      421 ttgtgataat taagtttata agaaaaaaat cttttaagta tttggttcta tatccattta
      481 cttatgatgg gagctggaga tttcaaccta taaacttact ctactttcca gaaatggtga
      541 gagatgtcat tccgattaat ttagttcaag aatattgcca aggacaacct tacggactgt
      601 taaaaaagat gctgaaaaga attcgattgt cacgagagat agctttactc ctggctacca
      661 ttatcgtcta tttttttacg catagaattc tacctctttc agtatttacg ttcatatttt
      721 cttacatatt gctatttgca caatcttatt tgggtggtaa taccgtttgg attggaaata
      781 gaagattaat aatagatgat gaatttgaaa aaatcttgct ttcaaaaagt tatataaaag
      841 aaatatcatc tgcacgatac tcggaatact tgacatgtga atacaaaaac cttacaccaa
      901 tcatattgtt agctattttt gaaaatttgc ttgactccta cttgcttcag aatcagagtg
      961 aggttgactt agatattttt tataaagttt tacctttgct ttataaagaa aaatatacta
     1021 tgggattcaa ttactttgta agtttaaatt atttactata taaggttgga tttttgggaa
     1081 tcatttacga taatgaagca ttaggagatt tgtcaaaaca atatttaaac agaaatattt
     1141 cggaattaca agatggttct ttcgatggcg gtatacaaga tgctgttgcc tctaaacaaa
     1201 tagtagttat aaatgaattt atagcttgtt taaattccag atgcatgcca tcccaatatg
     1261 atagattttt ttataaagat agaccttata ttttttccag aaagagtcct attaaggggt
     1321 gaaaatttgt tacatttgga ttaacaagtg tcctagggat tagaaataac tctagtatag
     1381 ctagatattt ttgagtaact agaaatatca ttaggctacc catatgattg ccagaaaaga
     1441 tggctgatga atcttattta tactgttgca gtaggcattg tctaggataa ataagctatc
     1501 ttgatggggg aaattggaat aattttagta gaaacattaa aggattatgg acaagtagcg
     1561 caggattagg tgatgcaatg tgctaagttg gcttggtgtt agcagtagta ttatttaaca
     1621 atggaaagta gactaaatga aaaataagcg ttattttttt gacacaattt taatgatttt
     1681 actgcttata agcacgatat tttgtgtcag cccagtattt ataaaattgg acatcttagg
     1741 aaccccctct catgccatct taacctttgt attggcgata ccgttattct atattttgtc
     1801 tcaatgctta catactttgc tattactagt ttcctcaatc ttttgtaaat taagaccaat
     1861 ttatttttat tttatatttg tgatcattat aggagctagg aaatactatc gaattctctt
     1921 tcaccaacta atgggattta gtccaggaat agcagtgttt tataaggaga gtcaaacaac
     1981 taagaatctg tttaaatttt actacttctt gtactttaca acactaattt catactattt
     2041 tttctttact tttgtgtatg acaaaccgtt gcttttgcct cttattccat tttctattat
     2101 catagcatta gtacaaaaac tttatagaat tgagaatcaa caattatttc tgttaaaatc
     2161 aaaggtacta acaatactgg aatctaagaa gaattgtgag tttaatcttc aggattatca
     2221 tgaaatttgg aaattgcaat caaaatctga gttgccatgc gtggctttat cttatatcag
     2281 tttgatcaag ccatatcttt cagagagcgt gcgtgaacaa attgatttat tagaagttaa
     2341 gcgatttaaa aaaataaatc atccaatatc actttatggt atgttggatg ttataaaatt
     2401 aaatctatat ttacggcatt ataatgaaaa aaataaatat gaatcaatgt taaagaaaat
     2461 tttagaggta agaccagact ttgttttaat cgagcagaat attgatgata gtttaaatag
     2521 ctcgcaacca ttatctttat ctttagccat ttcagaaatc caacttttgc ttgaagtgta
     2581 tatggggatc aaacatgttt caaccaagtg ataaaaccag aataatattt gccattatag
     2641 gggcaagttg catattagtc agtatgtatc ttattccact tattaaaact gagaataaat
     2701 tttgggaaat acttttattt atattaggtg tattgctaat tggaattgcg ttactaagtc
     2761 aaaaaaaata aattttgaaa tagtattagt gagttcgcaa tcatttattg ctagtggttt
     2821 agaactgtta agtttcaaac aataattgat tttaaacctt aggtaaccta taaaaacaaa
     2881 taaggtagag aaaggatatc ttatctaggt agctaagtga taaaaacaca gtcgtctatc
     2941 acttgttagg aaactatcct aactatgctt aataaaaaag gagaaaataa atggaactcg
     3001 tattaccaaa taattatgtt gttcttgagc aagaagagat gatgtatctt gatgggggat
     3061 tttctattcc gagatggcct gttgcaacag ccattaatat agcttttaat ggtgttttag
     3121 gtggaggagc aatcagtcta gttagaaatt atattcgtaa ttatggtttg cggcgagtta
     3181 caagcgcaat tgctggagca gctgcaagat atgttggggt acgagttgca aatagagtgg
     3241 caggatttgc actgtctgct attaatggat ttgcagcttg gatgtcaatt ggcgatgcta
     3301 ttacaacaat ctgggccaac aatgatgtaa ataggagaga cccaaattta aacgccttgt
     3361 ggtaactaga tatgggtatt aaaatggaaa aaatttttgt tattattttt tttgtatgtc
     3421 tatttatatc atccataact tttttagcct atgattttgt tagcgaagaa ataaaaaagt
     3481 tgattatttg gattaatgtc gtttttttga ttttaatcat agcaatgatg atttatccaa
     3541 aattaagaaa atgataagga cactgtaaaa ttatgatacg taaactaatt gttttcttac
     3601 taatgctccc tctttttgtc ttgtggctag agttgcatgt cctagtgaat aacttactat
     3661 tgaatctaga atctcccctt gattttgtga ttagtatgag tcttgctttc tgtagtttga
     3721 ttttatcaaa aatagtttta gacatactat acgcattgaa agatttatac aagaaagaag
     3781 gtcttattaa gatttttccc tttattttta taagaaggaa aaaagtgaat gtgagattct
     3841 cgccctattt ttcattccat cgtaaaagtt tgtcgcctga tgatttaaga tctaggatta
     3901 tatggagttt tattcttgaa attgctatta tcctagtatt tattttaaaa attccttttg
     3961 caatcatcat gcttactaca atatttttct ggactataat ggatatcaat catctcgttt
     4021 ttaataagac ggaatttctt tttaatcaaa acaaatggca aaaagaagat tcatttgaaa
     4081 gtaatttgca taagatattg atggacaaaa tacaaaaatc agaattaagc tattctgact
     4141 taatgtccct tcttctctat gatgcgatga accaatccac ctttttaacg gatagtgaac
     4201 tttttgagga tattttgaaa aaaatcgaag attctcataa cacccttctg tgtacaggtc
     4261 ttgtcgagtt actgctgtat gagatttcta ttagtaacaa taacaactgg caagaaaagg
     4321 ttgataaaat tagaatacag ctcatcagaa tcaatcaatt agattttttc tattatacaa
     4381 gttggttaag gcaaaatttt gatttctgta tgaatagaga gtatcataaa atgaaatctc
     4441 ggaaattatt actgagtaat aaaaagatag tttaagttcg tcctatttgt aaaacaaatg
     4501 aaacaatttc aactaaggag gagaaaacaa atggaacttg tattaccaaa taattatgtt
     4561 gtgattgatg aagaagtaat gatgtatctt gatgggggag cttatttaag caagcgtgct
     4621 tgtcaaggaa tttgcgcagc agcaggtgta ttggctacag cagcagggaa aatagcttac
     4681 tgtattggat atggtgttct taatagaggt tgtgatatta acgagaaccc ttatccttgg
     4741 gatggattca tatctgcaac agtaagatga gtaatgtaga taagattcga aaaatacaca
     4801 tcatcgtgtg ttgggtgtat atatttttat cattcagggc gattataaat gatacggagt
     4861 attttttgct tattttttta gcttttatct actcaatagt atcactacct ctatattctg
     4921 tgaaaaataa aatagtatct atctgtctag ttataaattc gattctgtta atgagtttcc
     4981 ccattttaat caataagttt ttcccagaaa gttttttgac ttataccgta ttaataagtg
     5041 tttttatcct agagttagca atctttcatt taattaggaa agattttgat attaaattga
     5101 ctaacgaata taagaaaatt agtcagttta gaagcaaggt gtctcaatct ccttggataa
     5161 aatatttaga gatttctagt tttatattaa ctatatttcc atctattctt tatggtaaag
     5221 ttgataatca tgtactgact cttatctttt tgataaaaat ttgtgtagat actacgataa
     5281 aatttttatt catcagatta tttgacacaa gtactttaat gaagaggaga atattttttc
     5341 ttttcgcatt ggatgttata gcttacttat ttttaggata tcttttagtg attcaaaaag
     5401 caggctattt gttttcggtt ttacttcttt tttctaattt ttcagttcca tttatcaaag
     5461 aaaaggaata cgaattattt aaaaatagca agtaatagaa atatggatta aatcttagaa
     5521 cggcttaaaa tcagatatga taaagggaaa tagtcttatc taggtaacta agtgctacaa
     5581 acacaatcga ggatcacttg ttaggattac attttaatca tgcttaataa gaatggagaa
     5641 ttcctatggg gattgtatta ctctgaagtt tcgaatacct tagttctcgt gattttgagc
     5701 tattctagct ttagaatcct tcagaacgta aaattttaag cagtcaaaga cttagaatag
     5761 cctgaaaaca tttattttat agcaattcta ggcttagaat tgctcatata tatgtatttg
     5821 agctgctcga tagttaggac agctctattc tgagaaatct gagctatcaa tgcttcagaa
     5881 tagtatttcg ccaatggttt ttattgaaga ggtgattgtg ttatgatagt ctaaaataaa
     5941 attgatttaa tagagtaaat ggagaatcgt tacatgaaac atttttttgc aggaattggt
     6001 gagataaaac ttgttggcta cttattgtat atatgtgtag gactagcccc tctttttcat
     6061 atatatgtca taggttcgga actgagtttt gtgaaaatag tgttatctat tttgggagtt
     6121 atatttgtaa gtatgttaac tattgctcga atttatcgga cttttctata aagaatagtt
     6181 tggacttaaa ctgtatctaa aaacagaggt tggtcgatta tcagcctctt tcttgtcgtt
     6241 gaaaagagtg agatatattg acttttgaaa aaaagatgtc ataattgagt tgggataaac
     6301 ctaaaagtaa tatagtagat tgaatctgga atagtccgtt atgactgtta aaatatttct
     6361 agaaattaat ttgactttcc taatcgattt gttcacatct tgtttcaatc tactatactt
     6421 tctcgttaaa ccgttcggca attcatggtg acatggacac atagtagtaa gcacactatg
     6481 tggcttggca gagctaaaaa ctgttccctt gcgataagcc taataagcac aacataggga
     6541 gttagagaag ccgactctaa tcaaccactt tgggcaatag tgagaactgc cccgtgcttt
     6601 tttattttga gaaaatatgg agtttgtcgt tgaaattact tgattgtatt ttggactatc
     6661 aagaaagatt caatggaaaa acatgtcaag tatcaacgaa ttataagtat ttagagattt
     6721 tcaaagtgaa tttttgtttg actgatttac atcatttatt tgacttatac aaaatcacac
     6781 gagattatgc tagtcaaaca aaacctgcta ttcaagatgg tgtttttatt ttagaagatt
     6841 ttagaaatat cctatgtaca atgatgtaat cgaaaggata tctttatgtg agtttatcgg
     6901 cgatatcttc tatatctaag ctagcaagtt gttgcatcgt agctaaggat ttatctaaaa
     6961 atactatgaa attggacgtc atattttttg aggataaaaa taaaagatcc gcagttttag
     7021 gtttacgaag agacaaaagc ggagtattta aaccagttac tctacatttt acaagcgcta
     7081 agaaatatgc taaagttcgt aaaacagatg tgaaagaaat gaaatggcta taaagattgt
     7141 ccgcaggctt aagcttgcgt tttttgttgt ttaacgaaat taaaaaacaa gctctctcat
     7201 cggaaatgtt tttataggaa tgaaggaaga tgatgctatg tttaaaaaga gaatcgaaaa
     7261 gggcaaaagt agtgtcttta tctttttgga gtagaagctt atgatataga aatttgtaat
     7321 aaaaatgtaa tataaaacat ttgacaaata tttacggggg gagtatactt aatataagta
     7381 tagtctaaaa atgactatca gaaaagaggt aaatttagat gaataagaaa aaaatgattt
     7441 taacaagtct agccagcgtc gctatcttag gggctggttt tgttacgtct caacctactt
     7501 ttgtaagagc agaagaagct cccgtagcta gtcagtctaa agctgagaaa gactatgatg
     7561 cagcagtgaa aaaatatgaa gctgctaaga aggaatatga ggacggaaaa gctgctcaga
     7621 aaaagtatga agatgatcag aagaaaactg aggagaaagc ggaagaagaa agaaaagctt
     7681 ctgaagaaga acaagctgca aatctgaaat atcaacaaga gttggttaaa tatatacgtg
     7741 aaaatgatcc aacaaaaaaa gctgaagcta agaaagcaat ggatgaggct gagaaagagt
     7801 ataagaaaaa acaaacggaa tttgctgaag ttcgtgcaaa ggtaattcct agcgcggaag
     7861 aattaaaaaa gactagacaa aaagcagaag aggctaaagc aaaagaagca gaacttacta
     7921 aaaaagtaga agaagctgag aaaaaagtta ctgaagccaa acaaaaagtg gatgcagaac
     7981 atgctgaaga agtcgctcct caagctaaaa tcgctgaatt ggaacatgaa gttcagaaac
     8041 tagaaaaagc tctcaaagag attgatgagt ctgattcaga agattatgtt aaagaaggtc
     8101 tccgtgctcc tcttcaattt gaattggatg ttaagcaagc taaactatca aaacttgaag
     8161 agttgagtga taagattgat gagttagacg ctgaaattgc aaaacttgaa aaagatgtag
     8221 aagatttcaa aaactcagac ggtgagcaag ctggacaata ccttgctgca gctgaagaag
     8281 acttagttgc taaaaaagct gaattagaaa aaactgaagc tgaccttaag aaagcagtta
     8341 atgagccaga aaaaccagct gaagaaactc cagctccagc accaaaacca gagcaaccag
     8401 ctgaacaacc aaaaccagcg ccggctcctc aaccagaaaa accagctgaa gagcctgaga
     8461 atccagctcc agcaccacaa ccagagaagt cagcagatca acaagctgaa gaagactatg
     8521 ctcgtagatc agaagaagaa tataatcgct tgacccaaca gcaaccgcca aaagcagaaa
     8581 aaccagctcc tgcaccacaa ccaggttgga aacaagaaaa cggtatgtgg tacttctaca
     8641 atactgatgg ttcaatggct acaggttggc tacaaa
//
LOCUS       DAVAZV010000072         8559 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVAZV010000072 DAVAZV010000000
VERSION     DAVAZV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8559
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.072"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            221..2830
                     /locus_tag="VQT46_001919"
     CDS             221..2830
                     /locus_tag="VQT46_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lanthionine synthetase"
                     /protein_id="HET2371882.1"
                     /translation="MDYNFNLEHPFFFTNNDYSTDTSIKYQVSLPFNWHEVMNNDEWV
                     YQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGK
                     LVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFR
                     PSRDDEKKVAIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFI
                     IDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSEKLASECKALKILN
                     EWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIV
                     EKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGF
                     RAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREH
                     IDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKLLRGFTLTYG
                     QWRKEFQSRFFPVHYYGLNFNQGIAFSDLAILWSYQQLAKKVKNFKFDDYYEIRTQVI
                     NEAVNNFKKSSLSGLFDGKIGTIWLIYEFGEIDRAVELFTTHFIEIFENSQNKNLYSG
                     QAGILLVGLYFLSKGEIDNKLGEEILIRLREYTLNYIENPETFCKVGASDVQSNDPYE
                     NFGGLLYGHAGVAWLFGEAYKLTGESIYKNGLELAVDKELVAYKVDSNNSLQYSQGHR
                     LLPYLATGSAGLLLLINRNKEILSSKYLKYLTSLERATDVVFCVLPGLFNGFCGLEVA
                     NNIYSDIDDNFSGQKKLIEQLYRYLCVIEEGFVIAGDNGLKITTDIASGFAGVAIGLV
                     SIMDNKLTILPQI"
     gene            2863..4803
                     /locus_tag="VQT46_001920"
     CDS             2863..4803
                     /locus_tag="VQT46_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HET2371883.1"
                     /translation="MNQSNEIFLNTIQEKTHYKRSISSSFQELKKWNSLIFRRGRYWY
                     QFDNWSIPNTGVIKEWYVEDNDWIPKVSSSSLDNSNSLKIVFDVEKYTLPDDSILQDV
                     RISSDESYIVLVVSSLRSTNLIGIKKYTMEELFIIEDISVESSFYLGKFGVMYTRSKE
                     YGRPSKLFYKSFDSFTEEELFEENECSFRLKIVHIDSNNCFVKSVDFQKGRIFLYSFD
                     RTGFVRHSYTETVAPTPRDIALFSTEKAQYFLGLSSTEEKKDQLILRETSSGDRVSIT
                     IPYQDRARRVHCIGRYILLDCSNAANSVFYLATFKNNSLRELSVNKITFDEKTTLYEN
                     SFSDRVLLFLERRTFYEKILSFDLIENTLKTEFERPIIKSNNTKYFSKVIWTKKDSYD
                     VSIPISLFWKSEDTDELPRRKKCILSVYGAYGKNDNSDLDEIMLSIIDAGFIYAIVHV
                     RGGGYLGGEWYRSGKALNKWNSIRDFIEGVNYLRENDVIDSKRLGLITSSAGGIIAGA
                     VLNEEKNLLQSILLFSPFINPYDTLQNPNDPLSKTEIAEWGDIRDPEVKAYIKSYSPM
                     QNIEKARDSNTVIVNILGEKDPYINNNEVIEWSKKLNSIGVKSLLYLNKAAGHGGFTP
                     SDVLLMIDTLNYFFEEVGRNNL"
     gene            4800..6407
                     /locus_tag="VQT46_001921"
     CDS             4800..6407
                     /locus_tag="VQT46_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371884.1"
                     /translation="MNYLKFIKKTKLILMGILIFLSSFNGVLLSGIIVYAGSLNQTSS
                     FSDVLRFGAISILGWSAIYISNYYLEVTEASITKDINVKIKQGYFREQYLSSEMVKDY
                     SSIISVLSNDLRLIEENYFRQIFEIISSILLFIVSLSFMLYLNFLVSIIFIVLSALPI
                     IVPVFMKKMLSNSANEYSNSNAEYTHIIKEIFNGFKTLKSYSVTKEIISLSDKKLDKL
                     EDSTFNLKRSEVLSKLVAVLISGFCFLVPLVVGCYFVIYHKSLSFSELIGIFLANDKV
                     LGPIQSIAYSLNKINTTKDLRKPFLKYLSGEKNFIDAEHDNNGLYTSSIDEIHMKDVV
                     YSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLINGSLKPQKGYVNLLSHGKKS
                     SDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVLKKVNLYEELEKIDILNYQC
                     GENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDNDNSNSIHDILFNLGISFIE
                     VSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            6422..7162
                     /locus_tag="VQT46_001922"
     CDS             6422..7162
                     /locus_tag="VQT46_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371885.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            7165..8484
                     /locus_tag="VQT46_001923"
     CDS             7165..8484
                     /locus_tag="VQT46_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371886.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASLLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIASKWNLLYRKPY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLEDVLIDDMNLLGLILPNFIVSIILFILIFITKSSYFIFKNAKIIS"
BASE COUNT         2949 a         1060 c         1602 g         2948 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagagatt ctctggagtt atggatgtcg ttccaatatg tgcacgttgg aatgttagtg
      121 cttatatggg gagaatccaa aggattctcc ctttttattt aaataagtct gtctagctat
      181 agatatatta agtttgataa aatttcttgg agattttgtt atggattata atttcaattt
      241 ggagcatcct ttctttttca ctaataatga ttatagtaca gatactagca taaagtacca
      301 agtaagtctg ccttttaatt ggcacgaagt aatgaataat gatgagtggg tttatcaata
      361 ccctattgga aaatttgttg aaagacaagg gtggaaaata cacattagtt cagagtataa
      421 cagttcacat gaattgttac aagatgtagc aaaaatttgc catgaaatgc gaattccatt
      481 taaacatctt agtacagaag acaaatttat catgcgaaac gggaaattgg ttagtcgagg
      541 attttctggt aaatttatta catgttatcc aaatcaaaat gaattagagt cggttttgca
      601 aaggttagaa agtgccttaa agcaatataa tgggccatat attttaagcg ataaacgttg
      661 ggatgaagca ccaatatatc tgaggtatgg tgtgtttagg ccgtcaaggg atgatgaaaa
      721 gaaggttgct attgatgaat taattgttgg cgatgaagtt gttaaagatg aacgtttacc
      781 agtatttaaa attccaaaag gtatagtgcc ccctgacttt ttgaataaat ggcttgacaa
      841 gaaagataaa aaacagggag actttccctt tattatagat aatgcaatta gattttcaaa
      901 cagtggtggg atatataatg ctaggctaaa agaagatggg aaaaaaataa ttttaaaaga
      961 ggctagaccg tatacaggtc taggatttga tggtacttat tcttcagaga aattagcttc
     1021 ggagtgcaaa gcactaaaaa ttctaaatga atggagtgag acgcctaaaa tatactggca
     1081 cggtaagatc tgggagcaca ccttcttagg aattgaacat atgaagggcg ttccactaaa
     1141 tagatgggtt accaataatt ttcctttata tgaagttgtt gataagacca aagattatct
     1201 attgagagtt tcaaagatag tagaaaaact catcgattta acgaataagt ttcattctga
     1261 aaatgtatat catcaagatt tacatttagg aaatatcttg gttaaggatg aagatgagat
     1321 tagtataata gactgggaac aggctgtctt ttcaaatgat gaaaaagttg tacataaagt
     1381 tgcagcccct ggttttagag catggcgaga aacacttccc agtgagatag attggtatgg
     1441 tattagacaa atagctcatt atttatacat gccactagta actacatcgg atttgacata
     1501 caactatgta agtcaaacca ggatagaagg aaaaaaacta tttgagtctt tgggttatac
     1561 aagagaacat atagattatg tagaaagttt attgtcatat ctagattcta aatgtccaca
     1621 gattgagaat atttccagga aaaaagtttt aaaacccatg catgagatta gaactatcga
     1681 gagtgagcaa gatatacaag attttattat aaaattattg agagggttta cgctaactta
     1741 tggacagtgg cgtaaagaat ttcaatcaag attcttccca gttcattatt atggtctgaa
     1801 ttttaatcaa ggaattgcgt tttcagattt agctatcctt tggagttatc aacaactagc
     1861 taagaaagta aaaaatttca agtttgatga ctattatgag attcgaacac aggttattaa
     1921 tgaggcagta aataatttta agaaatcgtc cctttctggt ctttttgatg gtaaaattgg
     1981 tacaatctgg ctcatttatg aatttgggga gatagatcgg gcagttgaac tttttacaac
     2041 tcattttata gagatatttg agaattcaca aaataaaaat ttatatagtg ggcaggctgg
     2101 aattttactg gttggactgt attttcttag taaaggggaa attgataata aactaggaga
     2161 agaaatacta attaggctta gagaatatac tttaaattat atagaaaatc cagaaacttt
     2221 ttgtaaagtt ggcgctagtg atgttcagag taatgatcct tatgagaatt ttggtggatt
     2281 actatatggt cacgcagggg tagcttggct cttcggtgaa gcttataaat taactggtga
     2341 aagtatctat aaaaatggtc tagaattggc tgtagataaa gaattagttg cttataaagt
     2401 agatagtaat aattcattgc agtacagcca aggtcataga ttactaccat atctagcaac
     2461 tggaagtgct ggcctgcttt tacttattaa tagaaataaa gaaatcttgt caagcaaata
     2521 cttaaaatat ttaacttctt tagagagggc aactgatgta gttttttgtg tattaccagg
     2581 tttatttaac ggattttgtg gtcttgaagt tgctaataat atatatagtg atatcgatga
     2641 taacttttca ggacaaaaga aattaattga acaactttat agatatttgt gtgtaattga
     2701 agaaggattt gttattgcgg gagataatgg tttaaagata acaacagata ttgcttcggg
     2761 atttgcgggt gttgcaattg gattggtatc aataatggat aataaattga cgattcttcc
     2821 tcaaatataa tatttagata ccattattaa ggggtcatac ttgtgaatca gagtaatgaa
     2881 atatttttaa atacaataca ggaaaaaaca cactataaga ggtctatctc ttcatcattt
     2941 caggaattaa aaaaatggaa ttctttgata tttaggagag ggcgatattg gtaccaattt
     3001 gataattgga gtatacccaa tactggtgta ataaaggaat ggtatgtcga agataatgac
     3061 tggattccta aggttagttc ttccagttta gacaattcaa attcacttaa aattgtcttt
     3121 gatgtggaaa aatatacttt gccagatgat agtatcttac aggatgttag gatttcatct
     3181 gatgagagtt atatagtttt ggttgtatcc tcactgcgta gcactaattt aattggaata
     3241 aaaaaatata ctatggaaga gttatttatc attgaagata tttcagtaga aagttcgttc
     3301 tatttgggta aattcggtgt tatgtatact cgctccaaag agtacgggag gccaagtaag
     3361 ttattctata aatcttttga tagctttaca gaagaggaac tgtttgaaga aaacgaatgc
     3421 tcttttcgat taaaaatagt ccacattgat agcaataatt gttttgtaaa gtcagtagac
     3481 tttcagaaag gcaggatttt tctatacagt ttcgaccgga cgggttttgt tagacactct
     3541 tacacagaaa cggtagcccc aacacctaga gatatcgctc tatttagtac agaaaaagca
     3601 cagtactttc ttgggctctc ttcaactgaa gaaaagaaag atcaactaat tctaagggaa
     3661 acttcttcgg gagacagagt ttctattact ataccatatc aagatagggc tagaagagtt
     3721 cactgtatag gacgttatat ccttttagac tgttcaaacg cagcgaattc cgtcttttat
     3781 cttgctacat ttaaaaataa tagtttgagg gagttgagtg ttaataagat aacatttgat
     3841 gaaaagacaa cactttatga aaattcattt tctgatcgtg ttcttctgtt tttagagagg
     3901 agaacttttt acgaaaaaat acttagtttt gatttaatag aaaatacatt aaaaactgaa
     3961 tttgaaagac ccatcataaa atcgaataat actaaatatt tttctaaggt gatttggact
     4021 aaaaaagaca gttatgatgt aagcataccg atttctttat tttggaaaag tgaagatacg
     4081 gatgagctcc caagaagaaa aaaatgtatt ctaagtgtct atggggctta tggtaagaat
     4141 gataattctg atttagatga aattatgtta tctataatag atgcaggttt tatttatgct
     4201 atagttcatg taagaggtgg aggctatttg ggtggtgaat ggtatcgctc aggaaaggcg
     4261 ttaaacaaat ggaattctat cagagatttt attgagggag taaattattt aagggaaaat
     4321 gatgtaattg acagtaagcg attaggttta ataacttcta gtgcaggtgg aataattgct
     4381 ggtgcggtgt tgaacgagga aaaaaattta ttgcaaagca ttctcttatt ttcgccattt
     4441 ataaatcctt atgatacact tcagaatcca aatgatcctc tttctaagac cgaaatagca
     4501 gagtggggag atattagaga ccctgaagta aaggcttata taaagtcata ttcgcctatg
     4561 caaaatattg aaaaggcacg agactcaaat actgttatag ttaatatttt gggtgagaaa
     4621 gacccatata ttaataataa cgaagtgata gagtggtcaa agaaattaaa ttctattgga
     4681 gttaaaagtt tgttgtattt aaacaaagca gctggtcatg gaggttttac tccatcagat
     4741 gttctcttaa tgattgatac tttaaattat ttctttgaag aagtgggaag gaataactta
     4801 tgaattattt aaaatttata aaaaagacta aacttatatt aatggggatt ttaatatttc
     4861 tatcttcgtt taatggtgtc ttgctctcag gaattattgt atatgcaggt agtttaaatc
     4921 agacttcctc attttctgac gttctaagat ttggtgctat aagtattctg ggttggtcag
     4981 caatctatat atcaaattac tatttagaag taacggaagc atcaataacg aaagatataa
     5041 atgtaaaaat taaacaagga tattttagag aacagtatct ttcttctgaa atggttaaag
     5101 attactcatc tattatttca gttttgtcaa atgatttgag attaatcgaa gaaaactatt
     5161 ttagacaaat ttttgaaata atttcttcaa tattgttgtt catcgtctct ctaagtttta
     5221 tgctttattt aaacttccta gtttcaataa tatttattgt attatcagca ttgccgatta
     5281 tagtacctgt ctttatgaag aagatgttgt ctaattcagc taatgagtac tctaacagca
     5341 atgcagagta tactcacata ataaaagaaa tttttaatgg ttttaagaca ttaaaatctt
     5401 attctgttac taaagaaata attagtttgt cggataaaaa gttggataaa ctagaagatt
     5461 ctacttttaa tttgaaacga tcagaggttc tttcaaaatt ggttgcagta ctaatttcag
     5521 gtttttgctt tctagttccc ttggttgtag gatgttattt tgtaatttat cataaaagcc
     5581 tttcttttag tgaactgata ggtattttct tagcaaacga taaagtttta gggccgatac
     5641 aatcaattgc ctattcatta aataagataa atacaaccaa agatttaagg aaaccgtttt
     5701 taaaatactt aagtggagag aagaatttta tagacgctga acatgataat aacggactgt
     5761 atacttcatc aatagatgag atacacatga aagatgttgt atattctatt acaccagaaa
     5821 ataaattaag tattgacttc tcatttaagt caccatttag ggtattatta acaggaactt
     5881 ctggtagtgg gaaaacaacg attttaaatt taattaatgg ttctttaaag ccacaaaaag
     5941 gttatgtaaa tttgttatca catgggaaaa agagttcaga ttcaatacca acagttgatc
     6001 agacaccata tatttttgac actactattc gtgagaacgt aactttattt caaaatgaat
     6061 atttttcaga tgatcagata attgaggtgt taaaaaaggt aaatctatat gaagaattag
     6121 aaaagataga tatactaaat tatcaatgtg gtgaaaatgg tagtaatttg tctggaggtc
     6181 aaaaacaaaa aatagcttta gctagagctc tgattagaaa taataaagtg tacttatttg
     6241 acgaaatatc agctaattta gataatgata attcaaattc catacatgat attctgttca
     6301 atttaggtat ttcatttatt gaagtttcac atcattatga cttaaatgac aagagataca
     6361 ctgatatata taaattggaa aatggaacac ttttcaaaat taagtgattg gaggcaagaa
     6421 tatggataaa gattatatat taaaagtgaa agggctgtat catcaatttt tactaggaaa
     6481 taataaaacg ttgcaagtgc tgaaaaatgt ttctctttct gcttcgagag gagaatttat
     6541 aagtattcta ggaattagtg gttctggaaa gtcaacttta ttaaaatgta tttctagttt
     6601 gcttgaacca acaagtgggg aagtaatttt aaatggaatc aacccctata aaatcagaaa
     6661 tgcaaaattg tcaagtataa gacgtaacga agtatctttt atatttcaag catacaattt
     6721 aataccttcc ctgccggtaa tagaaaatat agcacttcct ttgcgattat cacaaaaaaa
     6781 attaactatt aaaaatgtag aaaacttact caaaagaatg aagtttaatg ctggcttaaa
     6841 cgattttgtt ggaactctgt ctggtggaga acaacagaag gttgctatag ctagagcggt
     6901 tattgctgat agtgatataa tatttgctga tgagccaact ggggctttag acagcgtttc
     6961 tcgtgaagta atttttgaat tattgagaga gttagtaggg gcgggtaagt gtgtaattat
     7021 ggtaacgcac gatatagaat tggcctcgaa aactgatcgt gcattaatat tgaaagatgg
     7081 aaaaattttc aaagaacttc atagacctag cggggaagag ttgtataaaa tcttagaggt
     7141 acaatcaact acggaggaat agagatgctc agattagttt actatcaatt tttacataat
     7201 aagaaacaat ggttaggcgt ttcaccagta atttttgttt cgagtttagt tatgggattg
     7261 gctgttaatg gggtaattaa tgttgagaat aattcgcaag tatttgtcgg acttccagat
     7321 cctaaaccaa tttttatgtt tccgatagta ttcggaggag taacattatt ctttgtgctc
     7381 tctaacataa taaatatgtt ggttgaaatt tttagagatg attacgaact tctggaggtg
     7441 ttgggagcaa gtctccttca actatcattt cttgtggggg gacagatttt tatcatttcc
     7501 tcgattatta gttttattgc atatctatgc tctatatttg ttacgtcaaa ttattattat
     7561 tttttacaat actttttcgg ggaaaatata ttacctgata tccaatttca aacgagtgct
     7621 gttggatgta tcattacagt agtgttgatt tcatttttag cctttctaag tggttgcttt
     7681 tatacgttca agaagattag aaataggaag agttctaaaa taaggcatgt tctttcaata
     7741 gtaaaaagaa tactgctatt ggctggtttt agtgttatct ggttgctttc tttgcaacaa
     7801 attttccaag atagcacaat tttagcgaag gcccagataa tattcaatat tgtaatctta
     7861 gatattgtga ttatttatca attatctcct tttatacagt catgttttat caaactactt
     7921 tctataatta tatttagaaa taattttatg ttcattgctt cgaagtggaa tttactatat
     7981 cgtaagcctt atataaaatc tatcagtgct gcaattacag gagctatatt actaatttct
     8041 agttttcaaa tgatttctca gaatatacta tctcaatttc aagatgacag tgatttagag
     8101 ctaaaagtgg catttattgt ctatgtagga gcaccaattt tgatagtact tgcaaatatt
     8161 atttcaattg catttttgtc atcgcatcaa gaaaggattg agattcagca atttgaaatt
     8221 ttaggaactt ctaattacca gatggttaag attaaagttg gtgaggctat atttttgaca
     8281 tttgttactt cattaattgc atttttactt aacattaaaa ttatggcttt aatatactac
     8341 tctttagagg atgttttaat agatgatatg aatcttttgg ggttaatact tccaaatttt
     8401 atagtgtcta ttattttatt tattttaata tttattacta aaagttccta ttttatcttt
     8461 aagaatgcaa aaattatttc ttaaaaattt gtaagttttc gctatataaa atagttaaat
     8521 ctattttgta tcattgcttg cattttactg gtggagaga
//
LOCUS       DAVAZV010000073         8550 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVAZV010000073 DAVAZV010000000
VERSION     DAVAZV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8550
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.073"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..128
                     /locus_tag="VQT46_001924"
     CDS             <1..128
                     /locus_tag="VQT46_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET2371887.1"
                     /translation="FQSLNQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(257..460)
                     /locus_tag="VQT46_001925"
     CDS             complement(257..460)
                     /locus_tag="VQT46_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371888.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(453..1535)
                     /locus_tag="VQT46_001926"
     CDS             complement(453..1535)
                     /locus_tag="VQT46_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET2371889.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1661..2443)
                     /locus_tag="VQT46_001927"
     CDS             complement(1661..2443)
                     /locus_tag="VQT46_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET2371890.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2443..3786)
                     /locus_tag="VQT46_001928"
     CDS             complement(2443..3786)
                     /locus_tag="VQT46_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET2371891.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQSL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(3885..5201)
                     /locus_tag="VQT46_001929"
     CDS             complement(3885..5201)
                     /locus_tag="VQT46_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET2371892.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQSLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5394..6615
                     /locus_tag="VQT46_001930"
                     /pseudo
     CDS             5394..6615
                     /locus_tag="VQT46_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
     gene            6814..8388
                     /locus_tag="VQT46_001931"
     CDS             6814..8388
                     /locus_tag="VQT46_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2371893.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
BASE COUNT         2454 a         1652 c         1892 g         2552 t
ORIGIN      
        1 cgtttcagtc gcttaatcaa ttggaacaag ctattgtaga ctatattgat tactacaaca
       61 ataaacgaat taaggtaaaa ctaaaaggac ttagtcctgt gcaatacaga actaaatcct
      121 tcggataaat taattgtcta actgtttggg ggcagtacat attcaacacc tgatactatg
      181 cgttttattg tgggaagatt ttcctcattt tctagtgaaa ttgaactttt tctaacatct
      241 tttgatagat gacttcttaa tcaattatca tttccattgt tgtttcttgg ggtttcatcc
      301 cttgtctttg ataaaagcgg agagcaccct cgttatcatt ccagacactt agggttagat
      361 tattgcagcc aatttcttta gcataatagc agaaaaatga caataaaata gcccctagat
      421 attttgaaag gaaagcatag gggctatata gtttaatcaa aataaagcaa atctttgctg
      481 gtgcttgtaa agaggtcgaa gccatccttg gtaacaacac cgcagtcttc aatacgaaca
      541 ccgactttac cagggatata gatacctggt tcaacagaga agcacatgcc ttcttcgatg
      601 accatgtcgt ttccttccat gatagatggg aattcatgga catccatacc gataccatgc
      661 ccgagacggt ggttgaagta ctcaccataa ccagcttttt cgatgacctc acgggcagcg
      721 cggtccactt catgagcagt cacacctggc ttgataaagt caagagcagc ttgttgggct
      781 tcaagagtca agttgtaaat atctttcttg aattggtctg gtttgccgac agcgactgta
      841 cgagtcatat ctgacgcata gccattgacc agaacaccca ggtcaaagag gagaagagca
      901 tcattttcaa ccttattagc tgctggaatg ccgtgtggat tcgcagcatt atcaccagtc
      961 aagaccatgg tatcaaagct catttcataa ccttcacgtt tcatggcaaa gtcgatttgt
     1021 gcgatgatat ctgtctcagt cttatcaaga gaaatattgt caaaaccaac atgaacagcc
     1081 ttgtcagcat aaagacctgc aaccatcatt ttttgcactt catcagctga tttgatgagg
     1141 cgcatgcgtt ggatacgagg agtgaggttg tcaaactcag cagtctcaaa aactgttttc
     1201 aaaccatggt atttggtcaa gatgagattg tcaaactcaa cagcgacacg tttgaagtca
     1261 agttgtggaa gagcatgttt gattttttgc catggatttt cagaatcgac atagcccact
     1321 actgggaagg aaacggtgct acttgcacgt tctacttcaa gagctgggac aaagaggaga
     1381 ggttcctgat ccgctaggac aaagaggaac atttggcgtt catggggatc actgtaaaaa
     1441 ccagtgaggt aattgattgt gacggggtca gatacgacag cgacgtctag tttttctgat
     1501 tcaagatatg ttaggatttg ttgtaattta gacatatgct accttctttc tacccctcta
     1561 ttttggcaaa aaatgagaga aaatgcaagg gagaagggta aaagaaaaga caaaaaactc
     1621 cgacaagata acggagttct ttgatatcat tttcctttgt ttaagaaaag tcagccttgc
     1681 ttttgacgtc actgtactct tcagcgattt cttggctgag aatgtcctca taggcaggga
     1741 gttggatgtc ctgaccatat ttcttcttga gggcagtagt aactaggcga taagccagat
     1801 tggcattacg agagaggata ggcccgtgga agtaggaacc aaagacattc ttataatgaa
     1861 ccccttcacc gaccttttct tcgttgtttc catttccata gacaacctgt cccagcggtt
     1921 tttggtcatc agagaggaag gtacgacctt ggtgattttc aaatccatag taggtttcat
     1981 cgaaatcttc attgtgaatc ttgatgtcac cgataaaacg gttattggtc tggttgagcg
     2041 tgtagtgtcc catgacccct agcccttcga tacgttttcc tgaagcttca acataatatt
     2101 gacccaatag ttggaaacca ccgcagatag ccagaactac accgtcgttt tggatgtagt
     2161 tgtcaatgct ctctttttta gcaggtaggt cgtctgcaat gatactttgt tcaaagtctt
     2221 gaccaccacc gaaaaaggcg atgtcgtagt gattttcatc aaagtcatca tggagagaaa
     2281 cgatgtcaac ggtcacatgg gctcccagtt tttcagccac atacttgagc atgaggatgt
     2341 ttccattgtc cccgtaggta ttcatgagat ttccgtagag gtgggcaatg ttgagctgat
     2401 aggggtaatt gctatctttt gaggaaagtg aagtataaac cattagttca tctcctttct
     2461 aacaatctga cgactagcca gcagttcacg aaattccagc atggcagtat aagttgccag
     2521 aatataggca tgcttgcagt cttgattctc aatggtcttg agaacttgct ccagattact
     2581 cgtttcagtg attttctcag ctggatagcc agtcactcgg aggcgacgag cgatttcaga
     2641 atgacgaaca ccgccagcgt tgatttcagg aatgtccatg tcagtgattt gctcaaagtc
     2701 tgcatcccag atccagctag tgtcaattcc atctgcatag ttggcattaa ggaggacaga
     2761 taggctaaat ggataaggtg ctagtttgat catttcgata gcttgggttg caccgactgg
     2821 atttttaatc aagacaaggg tacattcctt gtcaccgata tgaaaggttt cttggcgtcc
     2881 aaagacagca cggctcttgt caaatccctg tttgatgagt tgggaatctg cgccgaggaa
     2941 acgggcgatg gccacagcag ctagggcgtt atagatatta tagagcccgc cgatttggat
     3001 accgtattct tggccgtcta tgacaaagcg agagcgattg ttggtcaact caaccagttt
     3061 tgtcaaacga tagtcgagat caggacgttt acatccacaa ccttcacaga tataggcacc
     3121 caagtttgca taggtattat gctcatattt gaggatgcct tggcagtcag gacagagaat
     3181 cccttcggta ttgtagtgag ccagttgggc tggtcctttt tccaagtcaa aaccaaaata
     3241 ctctataggg tttggaatag ttggcttgta gaaaagtgga ctgtctccgt taaggagaac
     3301 agtagcagtt ggaacttttc gaatggcatc caatatcatg ttataggtag tatagatttc
     3361 accgaaacgg tccatctggt cacggaagat attagtaatg acaaaaagac taggctggat
     3421 atagtcacag atacgagata gactggcttc gtcaatttcg aggacggcaa tatttttccc
     3481 agtttttgaa gatttggctg ttaggaaggt tgttgcaatc cctgtaatca tgttggcacc
     3541 gcttgggttg gttagaactt gaccataaac ctcttttaaa atgccgacag tgagggcagt
     3601 tgtcagggtt tttccatttg ttccagtgac aacgacaatc tcgtagttct tagctaggct
     3661 ttgtaaaata tctttatcaa attgaagggc gactttccct gggagcgtac ttccacgtcc
     3721 aagacggctt aaaacgaagt gggaagaacg cccagcaaga aggcccaaag tagtttttaa
     3781 gttcatgttt ctattatatc acaaaagagg gaaaagacag atttggtgtt tcgtagaagt
     3841 aaaaacagcc caaagagggc tgtcagttaa gatgagattt caacttaaat cgcaaacaag
     3901 tcattcaagt tctcagccaa ggttgggtga gtgaagattt gttttgtgaa gtaagtgtaa
     3961 ggaatcttgt tgtccatagc aacagtaatg atgttgatga tttcttgaga accttctgag
     4021 aagatgcttg caccaagaat ttcttttgtt tcagtattaa caacagcttt gaaagctccg
     4081 cgaaggtctc catttacgtg accacgaggc atggctgcaa cagggatttc tttcactgcg
     4141 tatggaagtt tcaaatcagc tgcttggctt tcagtcaaac caacttgtga aagtgcaggt
     4201 gtgatgaaca tagtatttgg cacattgaga cggtcctcaa gtgtgtagct gccatctcca
     4261 gcaaggtagc tgtaaacaac acggaagtca tcaagtgaaa tgtaagtaaa ttgaaggcca
     4321 ccgttgacat ctccaactgc aaagacacca ggaacgtttg tttgacagtg tttgtctact
     4381 ttaatagcac cacgttcagt tagttcaata tctgtatttt caagttgaag tggttctaca
     4441 tttggtttgc gtccagttgc gtagagaagg gcgtcgaaac ggtaagtttc gtcttcagtt
     4501 acgacaagca cttggtcacc atcgtttttg atttcagtag tatggatatt ttgaagcaat
     4561 tcaatgccat cttcttccat gtattgttta gcaagagctg cgatggaagg ttctgcacga
     4621 ggtaggaatg tatccaaggc atctaggact gtgaccttgc ttccaagttt gttgtaaagg
     4681 ccggcaaatt caagaccgat atttccgcca ccaaggattc caagtttttc aggtaatttg
     4741 tccaagcttt ggatacctgt tgagtcaaag atgtttttgc ttgtagcaag tccaggaatt
     4801 ggcaagacgt ttgaaacagc accagtgttg atgacgattg tttcagcagt cagttctttc
     4861 ttttcatcac cagcttggat ttcgatgact ttatttgaaa ggaagtgagc ttccgcatca
     4921 aagatatcta cgcctgtacc agcaacagtc gcatagtttt taccgttgag gcgaccagtg
     4981 atcgtgtttt tagtagcaat cacttcttca aaagacaagt ccttttcagc agcaactagc
     5041 aaggttttag ttgggataca accaatgttg atacaagttc caccgtacat agccttgctg
     5101 cgttcaacga gggcaacttt tttgccagct gaagccaatt tacctgctag tgttttacca
     5161 gctttaccaa atccaataac aattaaatcg tatgttaaca tttatcttcc tcctattcga
     5221 atttcattct agcacaagaa aaaaactttt gcacaattct gctacggaaa agacagaaaa
     5281 agataaaaac gctttccaga caaaaaacta gtaatttttt gacaagcttg ataaactaaa
     5341 atcctatcta tttttatata agaaagaata aatgttcgaa aataggaggt tttatgaaat
     5401 cgaatcgtta tattattgcc tttgctgggg tcattttaca cttaatgctg ggttcgactt
     5461 atgcttggag tgtttatcgt aaccctatta ttgaaaaaac gggatgggat caggcttctg
     5521 ttgccttcgc ctttagtcta gcaatctttt gtttgggctt atcggctgca tttatggggc
     5581 gtttggtaga aaaatttggt ccgaaagtca tggggagtct atctgctttt ctatacgcag
     5641 gtggaaatat cttaacagga tttgcaatag accgtcagga actgtggttg ttgtatctag
     5701 cttatggcat tttaggtggg cttggtttgg gagcaggcta tattacccct gtgtcaacga
     5761 ttataaaatg gtttcctgat aaacgtggtc tcgcaacagg tttagcgatt atggggtttg
     5821 gttttgcttc tttattgact agtcccatag cgcaacacct catcgcaggg gtagggattg
     5881 tagaaacttt ttatatttta ggagcaagtt actttattat catgctccta gcttcacaat
     5941 tcattaagcg tccaaatgag caagagcttg caattttatc ttcttcaggg aaagaaaaaa
     6001 cagcctcttt gacgcaagga atggctgcaa atcaggctct aaaaagcaat cggttttata
     6061 tgctttggat tattttcttt atcaacatag cttgtggttt aggcttaatt tcagcggcat
     6121 cgccaatggc acaggagatg gctggcttgt ctacaagtca tgcagcagta atggtgggtg
     6181 ttttggggat tttcaatgga tttggtcgct tgctctgggc gagtttgtct gactatatcg
     6241 gtcgccctct aacctttagt atattactgc ttgtcaatct tttctctctc actttggctc
     6301 tttacagatt ccgttttatt tgtagttgct atgtctattt tgatgacttg ctatggagct
     6361 ggtttttctt tgattccagc ttatctcagt gatatttttg gaaccaagga attggccgct
     6421 ctgcatggtt atattttaac agcttgggca atggctggtt tagcgggacc tattttatta
     6481 gcagagactt ataaaatggc tcattcgtac acacaaacct tgttcgtttt tctcatttta
     6541 tacagtatcg ccttggcttt gtcttattat ctaggtcgtt caatcaaaaa agaaagtcaa
     6601 aaaccgctta catgattttc tgtagaaatg gggctatctt ttgctctggt cttgtgttat
     6661 actagatagg ttgcaaagaa aacagtactt ttcttttgtg gaaaagaagc aacacgattt
     6721 tatatctagt tatatgaaaa tacgtcataa aaagaaaagt ataaactaag ccctataggg
     6781 tggcttcgca ccacctttag aaagaagaat aacgtgaaat ttaatgaatt aaacttgtct
     6841 gctgatttgc tagcagaaat tgaaaaagct ggttttgtag aagctagtcc tatccaagaa
     6901 caaactattc ctttggccct tgaaggcaag gatgttatcg gtcaagctca gactggtaca
     6961 ggaaaaactg cagcctttgg cttgcctacc cttgaaaaaa tccgtacaga agaagcgact
     7021 atccaagctt tggtcatcgc tccaactcgt gaactagctg tccaaagtca agaagaactc
     7081 ttccgctttg gtcgtagtaa gggagtcaaa gtccgttcag tatatggcgg atcaagcatt
     7141 gaaaaacaaa ttaaggctct taaatctggt gcccatatcg tggtgggaac tccaggtcgc
     7201 ctcttggact tgattaaacg caaggccttg aaattacaag acattgaaac ccttatcctt
     7261 gacgaagcgg atgaaatgct taacatgggc ttccttgaag acatcgaagc cattatttcc
     7321 cgtgtacctg agaaccgtca aactttgctt ttctcagcaa ctatgccaga tgccatcaaa
     7381 cgtatcggtg ttcagtttat gaaagcccct gaacatgtca agattgcggc taaggaattg
     7441 acaacagaat tggttgacca gtactatatc cgtgttaagg aacaagaaaa atttgacacc
     7501 atgactcgtc tcatggatgt ggcacaacca gaactcgcta ttgtatttgg tcgtaccaaa
     7561 cgccgtgtgg atgaattgac tcgtggtttg aaaattcgtg gcttccgtgc agaaggaatt
     7621 catggcgacc tagaccaaaa caaacgtctt cgtgtccttc gtgactttaa aaatggcaat
     7681 cttgatgttt tggttgcgac agacgttgca gcgcgtggtt tggatatttc aggtgtgacc
     7741 catgtctaca actacgatat tccacaagat cctgagagtt atgttcaccg tatcggtcgt
     7801 acaggtcgtg ctggtaagtc aggtcaatct attacttttg ttgctccaaa cgaaatgggt
     7861 taccttcaaa tcattgaaaa cttgactaag aaacgcatga aaggtctcaa acctgcaagt
     7921 gtagaagaat ccttccaatc aaaaaaacag gtagctctca agaaaatcga acgtgatttt
     7981 gcagatgaaa ccattcgtgc caactttgag aaatttggta aggatgctcg caaattggct
     8041 gctgagttta ctccagaaga attggcaatg tatatcttga gtctgacagt ccaagaccca
     8101 gatagccttc cagaagtgga gattgcacgt gaaaaaccac taccgtttaa accatcaggt
     8161 aatggtttcg gtggtaaagc taagggaggt cgtggaggcc gtcgtgggga cgaccgtcga
     8221 gagcgtgatc gccgtggcaa tggtcgccgt gatgagttca aaaaaggaag tcgtggcaac
     8281 gatcgttttg ataaggaaaa acgttaccgt aaggataata aaaaaccacg caatacttta
     8341 agcgaaaagc aaacaggctt tgttattcgt aacaaaggcg ataaataaga aaaagcggtt
     8401 caaaatgaat cgctttttta tataaggaga ccgaatgtga aaagacaaat aaaattacta
     8461 tattatcttt tataatgtta tgatacacaa aaataggcaa cttgtcaata gaaaaggaac
     8521 aatttaatta aaaatattct ggtttttaat
//
LOCUS       DAVAZV010000074         8200 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVAZV010000074 DAVAZV010000000
VERSION     DAVAZV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8200
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.074"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(135..1103)
                     /locus_tag="VQT46_001932"
     CDS             complement(135..1103)
                     /locus_tag="VQT46_001932"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET2371894.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(1248..2063)
                     /locus_tag="VQT46_001933"
     CDS             complement(1248..2063)
                     /locus_tag="VQT46_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET2371895.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKKWELPKKVLILSLLGGMFLSGWLSSFTNTYIHDLLGVLFPD
                     SPFLNAFESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIG
                     YIRTDLPEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAHKEQKVGKKQGLI
                     FLGLALRTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            complement(2088..2585)
                     /locus_tag="VQT46_001934"
     CDS             complement(2088..2585)
                     /locus_tag="VQT46_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET2371896.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQT46_001935"
     CDS             complement(2658..4019)
                     /gene="radA"
                     /locus_tag="VQT46_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET2371897.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MSVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            complement(4033..4548)
                     /locus_tag="VQT46_001936"
     CDS             complement(4033..4548)
                     /locus_tag="VQT46_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET2371898.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGFPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            complement(4550..4993)
                     /locus_tag="VQT46_001937"
     CDS             complement(4550..4993)
                     /locus_tag="VQT46_001937"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET2371899.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            complement(5050..5147)
                     /gene="ffs"
                     /locus_tag="VQT46_001938"
     ncRNA           complement(5050..5147)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQT46_001938"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5180..5647)
                     /locus_tag="VQT46_001939"
     CDS             complement(5180..5647)
                     /locus_tag="VQT46_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET2371900.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            complement(5848..7134)
                     /locus_tag="VQT46_001940"
     CDS             complement(5848..7134)
                     /locus_tag="VQT46_001940"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET2371901.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGIGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGARNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(7365..7601)
                     /locus_tag="VQT46_001941"
     CDS             complement(7365..7601)
                     /locus_tag="VQT46_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET2371902.1"
                     /translation="MLQKIYEQMTNFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            7867..8200
                     /locus_tag="VQT46_001942"
                     /pseudo
     CDS             7867..8200
                     /locus_tag="VQT46_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2615 a         1967 c         1323 g         2295 t
ORIGIN      
        1 tgatgacgta cagtcatatt tcttctcttt ttattatatc acagttttaa atctagcttt
       61 actagattca ccgctactat ctatttattc ggaaaaaaga cgaaaaaacc tgagaatcat
      121 ctcaggcttg gtcattaaat ttttttctca atatcgaaaa gtggagaaag tggtcgtttt
      181 tcatgaatac gtacgatagc atcccctagg agatgagcga ttgaaatctg ctcaatctta
      241 tcaatcaaac gctcttctgg cagatagatg gtatccaaaa caaccaattt cttaatagct
      301 gatttttgga tattgtccgt agcaggacca gaaagaactg ggtgcgtaca gcttgcatag
      361 acttcaacag caccagcttc cgcaagagca tctgccgcat gacaaatcgt tccagcggta
      421 tcaatcatat catcaatcaa gatacaagtc ttgccttcaa ccttaccgat gatgttcata
      481 acttcactag tattcatctt atcaacgcta cgacgtttat caataatagc gatagatgtt
      541 ttcaaaaatt ctgccaactt acgagcacga gtcacccctc catggtccgg gctgacaacc
      601 acatagtcag aaccaaccat accacgacgc tcaaaataat ctgcaatcag aggagcaccc
      661 atcaaatgat ccacaggaat atcaaagaat ccttgaattt gcgcagcatg caagtcgatg
      721 gtcaataaac gatccactcc agctacttca agcatatttg cgacaagttt tgaagtgatt
      781 ggctcacgcg ctctcgcctt tctatcctga cgtgcatacc catagtaagg catgacaaca
      841 ttgacagatt ctgcactcgc acgcttcaaa gcatctacca taatcaaaat ttcaagcaga
      901 ttgtcattta caggcgaact agttgattgt aggataaaga cgtgtttccc acggattgat
      961 tcttcaatgt tgacctgaat ctctccatct gaaaattggc gaacacttga tttccccaac
     1021 tctatcccaa tctcctgcgc cacacgttct gccaattctt tattagaaga aagggcaaac
     1081 agctttaaat cagaaaaaga catgatttcc tccggtatat atgtatcgct tgtgcttttc
     1141 acaagatttt ccatctacca ttgtagcgct ttttgcacta tttttcaatc aaaaataaaa
     1201 gaagggcacc atatttgtac ccttgcatca ttcttttgaa aaatattcta ggtcatcaac
     1261 tcattgtgtt tctcaacaaa gcaataagca tgataaaaac catagagagc aatagccgta
     1321 accactggaa tcgctaaagg caactctgtt tccaactcca caaaaggaga gttaaacaag
     1381 aagtgagttc tcaaggctaa acctagaaaa ataaggccct gtttcttgcc aaccttctgt
     1441 tctttatggg ctctgtaaag caagtaaaca cctactacag ctagacctga aaaagtccag
     1501 tgagaggcaa ttcctgagat gatacgctct aaaattcgcg aaatagtaaa gtcaaagccc
     1561 tctggcaaat ccgtacgaat ataaccaata tcctcaatca tttggaatcc caaaccggaa
     1621 gcaattccaa gtaaaaacaa agattttaat tttcgcacag gaatcaaagc caaaacaaaa
     1681 acaagtggca ataatttcaa gggttcttct accaaaggag ccacaatagc actttcaaag
     1741 gcatttaaaa atggactatc tgggaaaaga acccccagta aatcatggat ataagtatta
     1801 gtaaaactag acaaccagcc tgaaaggaac atccctccca ataaagacag aatcaaaacc
     1861 ttctttggca attcccattt tttcccaata cggaagagaa aataaagagc cggaatcatg
     1921 taaaagagag ctagaaagat agaaactccc attagtccat attccgcacc tgacctcgaa
     1981 ccgtccgtat agtagatggt ttcatactgt aaaccaatac atagcaataa aataaaaata
     2041 aataaaatac tgcttttctt catacacttt ctttctaaat gaagtattta taattctacg
     2101 actgtcatac ttcctgtatc aacattgtaa atggcaccag agataatgac atcgtctggt
     2161 attaggggag actcgataag cagttgcata tcctcgcgta cactctcttc tatatcttgg
     2221 aagggcaaga agtcctggtc tgacacatct acacctaatt cctcttttaa atactcctga
     2281 aaaggttcat tttcaaaggt ctgagcacca cagtctgtat ggtgcaatac cacaatctct
     2341 cttgtcccca tttgttgctg ggaaataact agcgaacgaa tcatgtcttc agtcactcga
     2401 ccacctgcat tccgcaagat atgagcatcc ccaagtgcca agcccagagc ttgcgcaacg
     2461 tgcagacgag agtccataca ggtcacaata gctactcttg ttttgggttt aagtggcaga
     2521 tttaactgcc catgtagggc aacataagcc tgattagctt gcataaactg ttcaaaatac
     2581 gacacgattc cctccttgaa aatttgatag tcaaatattt ctcctatctt atcattttta
     2641 agagaatttg tcacggatta tgcaaagacc tttttcaaaa cttcctgaat cgttgtcacg
     2701 ccaatgacct gaatttcctt aggcagagtg attcctgtca aggaattctt aggtacataa
     2761 atcttagtaa agcccagttt agcagcttcg ttgatgcgtt gctcaatacg attcacgcgc
     2821 cgaatctctc ctgtcaagcc cagttctccg acaaaacatt cctgaggatt agttggcttg
     2881 tctttgtagc tcgaagcaat agcaactgca acagccaagt caatggcagg ttcatccaat
     2941 ttaacaccac cagcagattt gagataggca tcctgatttt gcaagagaag ccctgcccgt
     3001 ttttccaaaa cagacataat caagctagca cggttaaaat caagtcctgt cgtagtacgc
     3061 ttggcatttc caaacatggt cggtgttacc aaagcctgaa cctccgccaa aatcggacgc
     3121 gtcccttcca tggttacaac gatggaggaa ccagtcgccc catccaaacg ctcttctagg
     3181 aaaacttgac tcggattgag tacctcaacc aagccgcccg actgcatctc aaaaatccca
     3241 atctcattag tggaaccaaa acgatttttg accgctctca aaatacgaaa ggtgtggtga
     3301 cgctcccctt caaagtaaag caccgtatcc accatatgct ccaacatacg aggcccagcc
     3361 aaggttcctt ctttggtcac atgacctacg ataaagatgg caatgttatt ggtcttggcc
     3421 aactgcatga gttcagcggt cacttcacgc acctgagaaa cagacccctg cacccctgaa
     3481 atctcaggag acatgatggt ctggatggaa tcaataatga gaaagtctgg ctggatacgc
     3541 tccacttctg cacgaacact ctgcatattg gtctctgcat agagataaaa ctcactatca
     3601 atatcaccta agcgctctgc acgtagttta atctgctggg cagactcctc cccactgaca
     3661 tagagaactg tccccacttg ggacaactgg gttgagactt gtaggagaag agttgatttc
     3721 ccaatcccag gatccccacc gatgaggacg agacttcctg gtaccactcc gcctccaagc
     3781 acacggttga attcctccat ctccgtcttg gttcgattga cattgatgga agtcacctca
     3841 gctagtttca tgggcttggt tttctcacct gtcaaggaca cacgcgcatt cttgacctcg
     3901 gcaacctcaa cctcttccac aaaagaagac caagacccac agttggggca acgtcccaga
     3961 tatttagggg aattataccc acaattttga catacaaatg tcgctttttt ctttgcgatg
     4021 acaaacctct ttctatatct ctaactcaca ctcaatcact tggcaaaaat caatcttctc
     4081 atttggcaca aactggcgca tgagcattcg atgagcaaca actaccacag tctgatgttc
     4141 tcgatactta gacatacatt ctagaaaccg agacttcatt tccgtagctg tctcatattg
     4201 aataggacta ttaggaagca actccccctt gttttctaaa aacagtcttc tagctgtttc
     4261 aaagttttct attcctgttt tatagacctg ccattcatgt aataaaggct ctactcttaa
     4321 aggaaaaccc gtagcacata ccacatacga agccgtttct aaagctcttg tgactgcaga
     4381 agatacgatt atttcagctg acgagagtaa aggatttttg ctcaatttct ggacttgctg
     4441 ccgtcccatc tcagacaagg gtgccaaatc tatcccaaat cctatataag aacgctcctc
     4501 taactcacgg taatctggct ccccatgacg tacaaagata atcttcattc tagtgccctg
     4561 tcgatccaaa tccaccagtt cgaacgccat cagccgcatc tccatctgca attaagaaag
     4621 tagcaaaaac agcctggaca atacgctccc caacttcaag aacaacctct tggtctgtga
     4681 tattcttcat ctgcgcaaaa atatgccctt catttccagg atttccataa taatccccat
     4741 caatgactcc aactgagtta attaaaacca agcccttctt acgaggattt gaagaacgat
     4801 catagaggta gagaacctca gtcggctgca tataagcctt aacccctgtc ggaaccaaga
     4861 caatctctcc tggcgcaaca actgtacgca cagcaacctt taagtcgtaa ccagccgcat
     4921 gcgctgtctc acgcttgggc aataaatttt catctgtaaa actcgaaacc aattcaaaac
     4981 cacgaatttt cataattttc tcttttctat tatcatttat tctagattat tctatcttat
     5041 ttattcggaa aaagcacgaa aaaaagagca cacaattcaa atcgcttagg gctgctggat
     5101 tcctcccctg acccgcttca cgcagaactg ttgctccact atttattata tcacattcct
     5161 attcatttta aaagcaaaat tattttttcc gtctatttct aaaaaaatcc tgcatgatag
     5221 ctgcgcattc atcttccaaa attcctattt caacctccac acgatgatta agacgctcat
     5281 ctgtcaagat atcgtacaaa cttccagcag cgccaaattt ctggttttta gccccataga
     5341 ccacatttgg aatgcgggca agcccaatcg ccccactaca catgacacaa ggttcaatgg
     5401 tcacaaaaag tgtgcaatcc agcaagcgcc agctctcctc actcaagttc gcatcctcta
     5461 tagccataat ttccgcatgc ataaccgctc gctgtaattc ctcacgcgca ttatgcccac
     5521 gaccaatgat ttccccatct ttgacaatca cacaaccaat tggaatttca tcgtgttcaa
     5581 gagcaatctc agcctctctc aaagcctccc tcataaagac ttctttttct tcaagcgtat
     5641 aatacatctc ttttctcttt tcctacttat cgattttatt attatatcat gaatcccaac
     5701 acaaaaaaag ccaccgaatg cggtgactct atagggagat tattatgaaa aagaaaagtt
     5761 taggatattt gttacaacaa gttaggaggt cttcttgtaa ctgtctatag tatacccgac
     5821 ctatcttaaa caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg
     5881 ttcacgacca ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg
     5941 acgaacatag ttacgcgcat tctcaggaag atcttccaaa ttgcgagctc cggtaatatc
     6001 ttctgaccaa cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact
     6061 agctggatag tagtcaatac gttgaccgtc aagatcatag gccacacaaa ttttcacagt
     6121 atccaagccg ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg
     6181 acggctatga cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt
     6241 tgtaccatat tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt
     6301 tgggaaagga ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc
     6361 aatcttgctt ggaccgatac cagaaccaat tgtcacacca ccagctacag ggtttgatga
     6421 cgtaacaaat ggataagtac cttgatcgat atctagcata acaccttgtg caccttcaaa
     6481 aagcacacgt ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta
     6541 tttcttgatt tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc
     6601 tttactgtca tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg
     6661 ctcacggaaa atatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt
     6721 gtccatataa gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc
     6781 ttcttcttgc aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga
     6841 aatacgcaag ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag
     6901 agatttagga tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat
     6961 cccagatgga atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc
     7021 attatcacca ccttggtaac gtgcaattac ttctgcattc gctgaaagga agtctgtaat
     7081 cttcccttta ccttcatcac cccattgggt acctacaaca acaactgaag tcataatttt
     7141 gtctgagccc tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat
     7201 atcttacaat ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat
     7261 ttgctatttc caactattaa aaaatgattt agaaaaatta ctagctattt actattatct
     7321 ttccataaaa gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa
     7381 ccccgattca ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaacg
     7441 ataaaatccc tacgacaacc aatgccatat ctcactaaat aataaattaa aaatttaaaa
     7501 tgaacatgtt cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta
     7561 tcatagaaat tagtcatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct
     7621 tttttataaa cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt
     7681 aaaataccag cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc
     7741 tacctaaatt tcaaacgatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc
     7801 ctattagaac tataatattt atatatatgt attatggttc tgattttcta gtataaaaaa
     7861 attcaaacta gaattcttct tagaaaaggc cgttttaagt gctatcattg ctcaaaaatg
     7921 gaggtcgctg agacttctat cgtcaagaag aatcatcaaa ttccttgtat catcaaccaa
     7981 aagattgctc agaagttaat tgaaaagact tctatgaccg acattgatca tcagttgtct
     8041 atttcaactt caactgtcat tcgcaagatc aataattttc actttgagca tgatttttcg
     8101 cgtcttcctg agattatgtc ctaggacgtt gaaacagtcc ggggagtgac tgtttcaatc
     8161 gggagatgga gatgagcttt attgctcagg actttgataa
//
LOCUS       DAVAZV010000075         8107 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVAZV010000075 DAVAZV010000000
VERSION     DAVAZV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.075"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            120..497
                     /locus_tag="VQT46_001943"
     CDS             120..497
                     /locus_tag="VQT46_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2371903.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            732..2123
                     /locus_tag="VQT46_001944"
     CDS             732..2123
                     /locus_tag="VQT46_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET2371904.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            2237..3079
                     /locus_tag="VQT46_001945"
     CDS             2237..3079
                     /locus_tag="VQT46_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET2371905.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            3352..4113
                     /locus_tag="VQT46_001946"
     CDS             3352..4113
                     /locus_tag="VQT46_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2371906.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            4483..5400
                     /gene="glyQ"
                     /locus_tag="VQT46_001947"
     CDS             4483..5400
                     /gene="glyQ"
                     /locus_tag="VQT46_001947"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET2371907.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
     gene            5660..7696
                     /locus_tag="VQT46_001948"
     CDS             5660..7696
                     /locus_tag="VQT46_001948"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET2371908.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSELFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            7738..7995
                     /locus_tag="VQT46_001949"
     CDS             7738..7995
                     /locus_tag="VQT46_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET2371909.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
BASE COUNT         2554 a         1431 c         1794 g         2328 t
ORIGIN      
        1 gctttctttt ccgaataaat agatagaagc atagaatcta gcaaacctag atttaaaaat
       61 gtgctataat agaaggagga aaaggaggat tctcagacat ccaggtatca gcccaactaa
      121 tgatttgtca atttatccgc gatatgctgg acttgccagc aaaaaatgtg acgattttgg
      181 agggaagtaa cattcacgtc ttgccttcca tgccctactc agcgcaagat ttctatacta
      241 gtatagacgt cttggcggag ttagataatg gaatccaagt tatcatcgaa attcaggttc
      301 atcatcagaa ttttttcatc aatcgcctat gggcttatct gtgcagtcag gttaatcaaa
      361 acctagaaaa aattcgccaa cgtgaaggtg atacccacca gagctacaaa caaatcgcac
      421 tagtatacgc tatcgcaatt gtcgatagta attacttctc agatgaccta gcttttcata
      481 gttttatagt aaaatgaaat gagaacagga caaatcgatc aggacagtca aatcgatttc
      541 taacaatgtt ttagaagtat aggtctacta ttctagcttc aatctactag aaattccata
      601 gatagaaaac tacataatct ctacagatac ggatgttgga gttgatgtaa gatgctttgg
      661 cttgctagag gaattgtgga ttgccaaatt gtatcattga aattattgct caaatttgtt
      721 atgatataaa tatgaataaa agtagactag gacgtggcag acacgggaaa acgagacatg
      781 tattattggc tttgattggt attttagcaa tttctatttg cctattaggc ggatttattg
      841 cttttaagat ctaccagcaa aaaagttttg agcaaaagat tgaatcgctc aaaaaagaga
      901 aagatgatca attgagtgag ggaaatcaga aggagcattt tcgtcagggg caagccgaag
      961 tgattgccta ttatcctctc caaggggaga aagtgatttc ctctgttagg gagctgataa
     1021 atcaagatgt taaggacaag ctagaaagta aggacaatct tgttttctac tatacagagc
     1081 aagaagagtc aggtttaaag ggagtcgtta atcgtaatgt gaccaaacaa atctatgatt
     1141 tagttgcttt taagattgaa gagactgaaa agaccagtct aggaaaggtt cacttaacag
     1201 aagatgggca accttttaca cttgaccaac tgttttcaga tgctagtaag gctaaggaac
     1261 agctgataaa agagttgacc tccttcatag aggataaaaa aatagatcaa gaccagagtg
     1321 agcagattgt aaaaaacttc tctgaccaag acttgtctgc atggaatttt gattacaagg
     1381 atagtcagat tatcctttat ccaagtcctg tggttgaaaa tttagaagag atagccttgc
     1441 cagtatctgc tttctttgat gttatccaat cttcgtactt actcgaaaaa gatgcggcct
     1501 tgtaccaatc ttactttgat aagaaacatc aaaaagttgt cgctctaacc tttgatgatg
     1561 gtccaaatcc agcaacgacc ccgcaggtat tagagaccct agctaaatat gatattaaag
     1621 cgactttctt tgtgcttggg aaaaatgttt ctgggaatga ggacttggtg aagaggataa
     1681 aatctgaagg tcatgttgtt ggaaaccata gttggagcca tccgattctc tcgcaactct
     1741 ctcttgatga agctaaaaag cagattactg atactgagga tgtgctaact aaagtgctgg
     1801 gttctagttc taaactcatg cgtccacctt atggtgctat tacagatgat attcgcaata
     1861 gcttggattt gagctttatc atgtgggatg tggatagtct ggactggaag agtaaaaatg
     1921 aagcatctat tttgacagaa attcagcatc aagtagctaa cggctctatc gttttgatgc
     1981 atgatattca cagtccgaca gtcaatgcct tgccaagggt cattgagtat ttgaaaaatc
     2041 aaggttatac ctttgtgacc ataccagaga tgctcaatac tcgcctaaaa gctcatgagc
     2101 tgtactatag tcgtgatgaa taagcaagaa aaaataggtc tgttagatat ttgacagact
     2161 tattttttac agaatatagt actacttaaa aaatgtttta tgctataatt gatgaataaa
     2221 atagaaggag aagcatatga atacctatca attaaataat ggagtagaaa ttccagtatt
     2281 gggatttgga acttttaagg ctaaggatgg agaagaagcc tatcgtgcag tgttagaagc
     2341 cttgaaggct ggttatcgtc atattgatac ggcggcgatt tatcagaatg aagaaagtgt
     2401 tggtcaagca atcaaagata gcggagttcc acgtgaagaa atgttcgtaa ctaccaagct
     2461 ttggaatagt cagcaaacct atgagcaaac tcgtcaagct ttggaaaaat ctatagaaaa
     2521 actgggcttg gattatttgg atttgtattt gattcattgg ccgaacccaa aaccgctcag
     2581 agaaaatgac gcatggaaaa ctcgcaatgc ggaagtttgg agagcgatgg aagacctcta
     2641 tcaagaaggg aaaatccgtg ctatcggcgt tagcaatttt cttccccatc atttggatgc
     2701 cttgcttgaa actgcaacta tcgttcctgc ggtcaatcaa gttcgcttgg cgccaggtgt
     2761 gtatcaagaa caagtcgtag cttactgtcg tgaaaaggga attttattgg aagcttgggg
     2821 gccttttggt cagggagaac tatttgatag caagcaagtg caagaaatcg cagcaaatca
     2881 cggaaaatcg attgctcaga tagccttggc ctggagcttg gcagaaggat ttttaccact
     2941 tccaaaatct gtcacaacct ctcgtattca agctaatctt gattgctttg gaattgaact
     3001 gagtcatgag gagagagaaa ccttaaaaac gattgctgtt caatcgggtg ctccacgagt
     3061 tgatgatgtg gatttctaga aaatcataaa aagaattgta cattattcta atttttgata
     3121 taatagtcag caggaaagaa agtcttatgg cgttcttcaa gcgagcttgg gatagtggga
     3181 gccaagtagg gcaaaataat gagctggcgc tttctgtagt attttcaaaa acaatgaagt
     3241 aataaattag ggtggaaccg cgtttctgac gcccctaggt taaatcaacc taggattgtc
     3301 ggacgcggtt cttttgctta ttcagtctat tgtgtgaaag aaaggagagc cgtggacaac
     3361 ctttatcttg taaaagacga tagtcaacta gctacatttc gtgattttgt agtaagaaat
     3421 actgaaaagt tgaaagatta tcaatctttt ttaaagaatg aacttgcagt ctgtgattta
     3481 ccgcaagccg ttatttggtc agattttaat gctgctacac agattattag ggaaagcgct
     3541 gttccagcct atacaaataa tagacgaatg gttatggcgc ctgatttagc tgtttggaaa
     3601 gagttgtatt tgtatcaatt gatggactac gagtgttctc agcaaactca agcaatagaa
     3661 agtcactatc attctttatc tgaaaatttc ctcttacaga ttgtaggaca tgagttagct
     3721 cattggtcgg agcatttttt agatgatttt gatggttatg actcttatat ctggttcgaa
     3781 gaggggatgg ttgaatatat tagtcgcaag tatttcttga cagaagagga atttcaagcg
     3841 gaaaaaattt gtaatcaatc tctcgtagaa ctttttcaga agaagtatgg ttggcattca
     3901 ttgaatgatt ttggttcttc gacttatgat aagaactatg caagtatttt ttatgaatac
     3961 tggcgcagct ttttgacagt agataagttg gtagaaaatt taggtagtgt acaagcggtc
     4021 ttagattctt atcatttatg ggcaaataca gaaaaaactt ttcccttgtt agattggttt
     4081 gttcagcaga aattaattga aaaagaaata taaaaactaa aggagtaaac aatgtctaag
     4141 aaattgacat ttcactgcgt cagtggcaga aacctcctta cagtcggact gccccacgct
     4201 cagcactaga gtgcctgagc tagacgcagt actaactcgt cttgcctcgt atgatcgacg
     4261 aggcagactc atgtcgcaag taattatttt ttattaagga gtaaacaatg tctaagaaat
     4321 taacatttca ctgcatcagt ggcagaaacc tccttacagt cggactgccc cacgctcagc
     4381 accctagtgc tgagctagac gcagtactaa ctcgtcttgc ctcgtataat cgacgaggca
     4441 gactcgtgtc gcaagaaatc attttttatt aaggagtaaa caatgtctaa gaaattaaca
     4501 tttcaagaaa ttattttgac tttgcaacaa ttttggaatg accaaggttg tatgcttatg
     4561 caggcttatg acaatgaaaa aggtgcgggg acaatgagtc cttacacttt ccttcgtgct
     4621 atcggacctg agccatggaa tgcagcttat gtagagccat cacgtcgtcc tgctgacggt
     4681 cgttatgggg aaaaccctaa ccgtctctac caacaccacc aattccaggt ggtcatgaag
     4741 ccttctccat caaatatcca agaactttac cttgagtctt tggaaaaatt gggaatcaat
     4801 cctttggagc acgatattcg ttttgttgag gacaactggg aaaacccatc aactggttca
     4861 gctggtcttg gttgggaagt ttggcttgac ggaatggaaa tcactcagtt cacttatttc
     4921 caacaagtcg gtggattggc aactggccct gtgactgcgg aagttaccta tggtttggag
     4981 cgcttggctt cttacattca agaagtagac tctgtctatg atatcgagtg ggctgatggt
     5041 gtaaaatacg gagaaatctt tatccagcct gagtatgagc actcaaaata ttcatttgaa
     5101 atttcggacc aagaaatgtt gcttgaaaac tttgataagt ttgaaaaaga agctggtcgt
     5161 gcattagaag aaggcttggt acaccctgcc tatgactatg ttctcaaatg ttcacatacc
     5221 tttaatctgc ttgacgcgcg tggtgccgta tctgtaacag agcgtgcagg ctatatcgct
     5281 cgtatccgta acttggcccg tgttgtagcc aaaacctttg ttgcagaacg caaacgccta
     5341 ggttacccac ttttggatga agaaacacga gttaaacttt tagcagaaga cgcagaatag
     5401 tgagtaatac tgtactctaa aatcgttaga ggcaagtcga agacttgcta gagggatatg
     5461 caccgccgta ctgttatgtg gggatttttg aaaccttagg ttcaaaaatc agtcagctaa
     5521 atccactttg atgagattgt tggaaatctt gataaattta gcattggatt tccatacaga
     5581 ctcacagagt tagttagcga cgtccccagt acctaaggtg catatcaaaa aagattgaag
     5641 aaaatgtaaa ggaaaaaaca tgacaaaaaa cttattagta gaactcggtc ttgaagaatt
     5701 accagcctat gttgtcacac caagtgaaaa acaactaggc gaaaaaatgg cagccttcct
     5761 caaggaaaac cgcctgtctt ttgaagccat tcaaaccttc tcaacaccac gtcgtttggc
     5821 tgttcgtgtg actggtttat cagacaaaca gtctgatttg acagaagatt tcaagggacc
     5881 agcaaagaaa attgccttgg atagtgatgg aaactttacc aaagcagctc aaggatttgt
     5941 ccgtggaaaa ggcttgactg ttgaagatat cgaattccgt gaaatcaagg gtgaagaata
     6001 tgtctatgtc actaaggaag aagttggtca agcagttgaa gccattgttc ctggtgttgt
     6061 agatgtcttg aagtcattga ctttccctgt cagcatgcac tgggctggaa atagctttga
     6121 atacattcgt cctgtccaca ctttaactgt tctcttggat gagcaagagt ttgacttgga
     6181 tttccttgat atcaagggaa gtcgtgtgag ccgtggccat cgtttcttgg ggaaagaaac
     6241 caaaattcag tcagcattga gctatgaaga agaccttcgt aagcagtttg taatcgcaga
     6301 tccatgtgaa cgtgagcaaa tgattgttga ccaaatcaag gaaattgagg caaaacatgg
     6361 tgtacgtatc gaaattgatg cggatttgct gaatgaagtc ttgaatttgg ttgaataccc
     6421 aactgccttc atgggaagtt ttgatgctaa ataccttgaa gttccagaag aagtcttggt
     6481 gacttctatg aaggaacacc agcgttactt tgttgttcgt gatcaagatg gaaaactctt
     6541 gccaaacttc atttctgttc gtaacggaaa cgcagagcgt ttgaaaaatg tcattaaagg
     6601 aaatgaaaaa gtcttggtag cccgcttgga agacggagaa ttcttctggc gtgaagacca
     6661 aaaattggtg atttcagatc ttgttgaaaa attaaacaat gtcaccttcc atgagaagat
     6721 tggttccctt cgtgaacaca tgattcgtac gggtcaaatc actgtacttt tggcagaaaa
     6781 agctggtttg tcagtggatg aaacagttga ccttgctcgt gcagcagcca tttacaagtt
     6841 tgacttattg acaggtatgg ttggtgaatt tgacgaactc caaggaatta tgggtgaaaa
     6901 atacaccctt cttgctggtg aaactccagc ggtggcagct gctattcgtg aacactacat
     6961 gcctacatca gctgaaggag aacttccaga gagcaaggtc ggcgcagttc tagccattgc
     7021 agacaaattg gatacgattt tgagtttctt ctcagtagga ttgattccat caggttctaa
     7081 tgacccttat gcccttcgtc gtgcaactca aggtgtggtt cgtatcttgg atgcctttgg
     7141 ttggcacatt gctatggatg agctgattga tagcctttat gcattgaaat ttgacagttt
     7201 gacttatgaa aataaagcag aggttatgga ctttatcaag gctcgtgttg ataagatgat
     7261 gggctctact ccaaaagata tcaaggaagc agttcttgca ggttcaaact ttgttgtggc
     7321 agatatgttg gaagcagcaa gtgctctcgt agaagtaagc aaggaagaag attttaaacc
     7381 atctgttgaa tcactttctc gtgcctttaa cctggctgag aaggcagaag gggttgctac
     7441 agttgattca gaactatttg agaatgacca agaaaaagct ttggcagaag cagtagaaac
     7501 actcgtttta tcaggacctg caagtcagca attgaaacaa ctctttgcgc ttagcccagt
     7561 cattgatgct ttctttgaaa atactatggt aatggctgaa gatcaggctg tccgtcaaaa
     7621 tcgtttggca atcttgtcac aactaaccaa gaaagcagct aagtttgctt gttttaacca
     7681 aattaacact aaataaaatt tgataaacgg actttatctt attacaaagg agaagaaatg
     7741 gatccgaaaa aaattgctcg tatcaatgag cttgctaaaa agaaaaaaac agaaggctta
     7801 acaccagaag aaaaagtgga acaagccaaa ctacgtgagg agtacatcga aggttatcgc
     7861 cgcgctgttc gtcaccacat tgaaggaatc aaaattgtgg acgaagaagg aaacgatgtt
     7921 acaccagaaa aactacgcca agtacaacgt gaaaaaggat tacatggccg tagtcttgat
     7981 gacccaaatt cataatatgt actctttctt ttaacaaaga tagatgaaac gataacaaag
     8041 agactagcag tttgtgtttg ctagtctttt ttcgctaaaa aaggaaccat aatggttcct
     8101 aaaaact
//
LOCUS       DAVAZV010000076         7893 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVAZV010000076 DAVAZV010000000
VERSION     DAVAZV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7893
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.076"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            101..1078
                     /locus_tag="VQT46_001950"
     CDS             101..1078
                     /locus_tag="VQT46_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET2371910.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGVRFEAEK"
     gene            1075..2157
                     /locus_tag="VQT46_001951"
     CDS             1075..2157
                     /locus_tag="VQT46_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET2371911.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFELLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(2221..3270)
                     /locus_tag="VQT46_001952"
                     /pseudo
     CDS             complement(2221..3270)
                     /locus_tag="VQT46_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQT46_001953"
     CDS             complement(3654..4850)
                     /gene="tuf"
                     /locus_tag="VQT46_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET2371912.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(5761..6630)
                     /locus_tag="VQT46_001954"
     CDS             complement(5761..6630)
                     /locus_tag="VQT46_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET2371913.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(6853..7533)
                     /locus_tag="VQT46_001955"
     CDS             complement(6853..7533)
                     /locus_tag="VQT46_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2371914.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKAETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(7491..>7893)
                     /locus_tag="VQT46_001956"
     CDS             complement(7491..>7893)
                     /locus_tag="VQT46_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET2371915.1"
                     /translation="FKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKE
                     GSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAY
                     QKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
BASE COUNT         2299 a         1646 c         1489 g         2459 t
ORIGIN      
        1 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
       61 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
      121 cggaactggc gctatcagcc atcatttcat agaagcagcc cataccagtg gagaatacca
      181 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
      241 gaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
      301 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
      361 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
      421 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
      481 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
      541 tgccaaatac tcttccaaga tgcctgactt attggctgga caaacaccaa atgtcttttc
      601 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
      661 tcgtcttttt gaaaaagcta atgacgcgac ttaccatgct caacagcttg acaatagcat
      721 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
      781 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
      841 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
      901 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
      961 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
     1021 tgagctacta tataccatgc gccagactgc tggcgttaga tttgaggcag aaaaatgaaa
     1081 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
     1141 cccattcaaa ctcaactatt tgagctcctt cttgctggag aaaacctcct aggagtgagc
     1201 caaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
     1261 aaaaaagccc aacaactctt gattctagca ccaaacacgg aacttgctgg acagattttt
     1321 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
     1381 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
     1441 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
     1501 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagagaaa
     1561 atcactcact acgcacctcg tgaccaccaa ctggtctaca tgagtgccac gaccaagttt
     1621 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
     1681 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
     1741 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
     1801 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
     1861 aatgttaaat ttagaaaaat catcttagaa aagtttaaag ataaccaact aaccctgctt
     1921 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
     1981 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggtcgtatg
     2041 ggcaaggaag gttatgttat cactctcgtc actcatccag aagaaatcaa aaaacttaaa
     2101 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
     2161 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
     2221 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
     2281 cttctccaat ccttgtatga catcttgaag ttgattcatg acatcttcca aaattcgaaa
     2341 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
     2401 ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct ttaagatact
     2461 tgatttatgc catatagcat tgtccataac gagtaaaaaa taatcatctg gataagcttg
     2521 tgaaagcttt tctaaaaagg cgttcatcca ctcagtatta catctaccag ctattaagaa
     2581 aaatgattcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
     2641 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
     2701 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactata
     2761 tttaaaacgc tttcttgtct tcttgaattg agattttatt tttagacgcg acaatggttt
     2821 gagcgtctgc tttcttagga tgttctggac gtggcataat atttcgccaa ccatggcgct
     2881 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
     2941 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
     3001 gaaagacttt ctcttcctca actgtcatat atgcatggtt acgaccacca cgtgtttctt
     3061 gaaggagaga gtcgagtccg aactcctcat atttttttac atttcgccaa atcattgttt
     3121 gattacagtc taaaagttct ataatctctt tataagattt gcccatatca gacgaaatag
     3181 aacgatttga agacgtttat gatatttagc tgtacgagag tcttttaaaa gtgttttgat
     3241 ggtttggatt tcttctttaa ttgatttcat attactattg tataatgctt tttgatttta
     3301 gtctagtatt atactcttcg aaaatctctt caaaccgcgt cagcttcgcc ttgtcgtata
     3361 gatgttactg acttcgtcag ttctatctac aacctaaaaa cagtgttttg agcagtctgt
     3421 agctaacttt ctatagtaaa atgaaataag aacaagacaa atcgatcagg acagtcaaat
     3481 cgatttctaa caatgtttta gaagtaaatg tgtactattc tagtttcaat atattatagt
     3541 ttgctctttg attttcattg agtattagtt caatatctaa aaaaagaacc ttgccaagca
     3601 agattctttt agtgtctgac ttaaataatt gttcttctgg gaactaaatc gaattaagct
     3661 tcgatttctg taaccatacc tgaaccaaca gtacgtccac cctcacggat agagaatgta
     3721 gtaccttgtt ctacggcgat tgggtgaatc aactcaacgt cgattgtcac gttatcacca
     3781 ggcattacca tttcagtacc tgctggaagt tcgattgaac ctgtaacgtc agtagtacgg
     3841 aagtagaatt gtggacggta gttgttgaag aatggagtgt gacgtccacc ttcttcttta
     3901 gtaaggatgt agacttcacc tttgaattta gtgtgtgggt tgattgaacc tggtttagcg
     3961 ataacttgtc cacgttcgat ttcatcacgt tgaacaccac gaagaaggac acctacgtta
     4021 tctccagcaa gaccttcgtc aagttgttta cggaacattt caacaccagt aacaactgct
     4081 ttttgagttt cttctttgat accaacgatt tcgatttcgt cgttgacttt aacgatacca
     4141 cggtcgatac gtcctgaagc aactgtacca cgtccagtga ttgagaatac gtcctcgact
     4201 ggaagaagca atggtttgtc agtgtcacgt tctggttctg ggatatactc atcaactgtg
     4261 ttcatcaatt ccataacgat gtcttcgtat ttagagtcac cttcaagagc tttaagtgct
     4321 gaaccttgga taactggaag atcgtcacct gggaagtcgt attctgacaa taggtcacgg
     4381 atttccattt caaccaattc aagcaattct tcgtcgtcaa ccaagtcaac tttgttcatg
     4441 aagacgataa ggtgtttaac accaacctga cgtgaaagaa ggatgtgctc acgagtttgt
     4501 ggcattggtc cgtcagttga agctactaca aggatagctc cgtccatttg agcagcacca
     4561 gtgatcatgt ttttaacgta gtccgcgtgt cctggagcgt cgatgtgagc gtagtgacgt
     4621 ttttcagttt cgtactcaac gtgcgcagtg ttgatagtga taccgcgttc gcgttcttct
     4681 ggagcagcat cgatagacgc atagtcttta ggttggttaa ctgatgaagg caagcgacgt
     4741 gccaaaacag ttgtgatagc tgcagttagg gtagttttac cgtggtcaac gtgtccgata
     4801 gtaccaatgt taacgtgtgg tttactacga tcgtattttt cttttgccat ttgagtaaaa
     4861 gcctccaata aaatatattt tatagataga cagtaggcaa tacagtctaa ctttccttac
     4921 tattttatca aatttcagct aaattgcaag tgttttacaa cgtttttgtg aattattctt
     4981 ggtaaaaatt taactaatta atagaaagta ctaaatagac ttatccttca aggagttttc
     5041 agcattatcc atccactcac ttgctgaaaa tgtaaacagt ctctggttta tatagtaaaa
     5101 tgaaacaaga atagagcaaa tcgatcagga cagtcaaatc gatttctaac aatgttttag
     5161 aagtagatgt gtactattct agtttcaatc tactatacaa cctcaaaact gtgttttgaa
     5221 caacctgcgg ctagcttctt agtttgccct ttgattttca ttgagtataa aattgcagat
     5281 aaaacgataa caatcatagg actcagcaga gtcaatgtag gtcgaagaat agccccccta
     5341 atcgcttatt ttatagcaaa atgaaataga aactgaacat tttgttgagg aaggtaaatc
     5401 aattcctcac aatgtttgag aaagaaggga ggactattcc aacttcaacc cactataaag
     5461 cagacttaca agatagggaa cccatctccg ataatatata gtagaatgaa aactgcacaa
     5521 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     5581 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     5641 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     5701 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     5761 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     5821 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     5881 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcaggtcc
     5941 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     6001 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     6061 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     6121 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     6181 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     6241 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     6301 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     6361 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     6421 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     6481 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     6541 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     6601 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     6661 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     6721 aaaataggat tcatagtttc ccagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     6781 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct ggttcctaga
     6841 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     6901 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     6961 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     7021 ttcagctttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     7081 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     7141 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     7201 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     7261 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     7321 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     7381 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     7441 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     7501 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     7561 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     7621 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     7681 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     7741 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     7801 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     7861 aaacttgcag aatttgtatc tgcttcttta aaa
//
LOCUS       DAVAZV010000077         7652 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVAZV010000077 DAVAZV010000000
VERSION     DAVAZV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7652
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.077"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1038
                     /locus_tag="VQT46_001957"
     CDS             <1..1038
                     /locus_tag="VQT46_001957"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit I is part of the
                     membrane proton channel; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HET2371916.1"
                     /translation="IKVMDERFGHSIYIYESETLSDNQDEIPIKLTNHSLIEPFELLT
                     EMYALPKYYEKDPTPVLAPFYFTFFGMMVADLGYGLLLFLGTMLALKIFHLPSETKRF
                     LKFFNILGVAVAIWGGIYGSFFGYELPFHLISTTSDVMIILVVSVVFGFITVFAGLLA
                     SGLQKVRMKKYAEAYNSGFVWCVILLGLLFIAVGMLMPDMRLLFVLGKWVSIFNAVGI
                     LVVSIIQAKSLSGIGAGLFNLYNISSYIGDLVSFTRLMALGLSGASIASAFNLIVGLF
                     PGTLAKLTIGLVLFILLHAINIFLSLLSGYVHGARLIFVEFFGKFYEGGGKPFQPLKA
                     SEKYIKVITKN"
     gene            1054..1530
                     /locus_tag="VQT46_001958"
     CDS             1054..1530
                     /locus_tag="VQT46_001958"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HET2371917.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            1564..2145
                     /locus_tag="VQT46_001959"
     CDS             1564..2145
                     /locus_tag="VQT46_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371918.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSVIVKK
                     KEVEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALIEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNHLFSEQPISNESGLLI
                     SIGKIDDNYLYKTLIGSISKEESSSIANQIFIN"
     gene            2210..3217
                     /locus_tag="VQT46_001960"
     CDS             2210..3217
                     /locus_tag="VQT46_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HET2371919.1"
                     /translation="MDTNLFSKINTTISVKENDFITEDKFQKIIQSKDTETMAFILEA
                     TPYHLSIDVLENPSQTETSLMTKLVNDYRWAYAESPSNKIVTLFALRYVYHNIKVLLK
                     SKAAIKKDFSKLLIPIGIFDIESLKHLVSSLHSDTLPDFMVHEVESIWNEYETFNNIR
                     VLDVGADLAYFKHLKLLSNELDEVLSQVIVAMIDFYNIITVKRGLSQNKSHGDILQLL
                     SDEGSISAKEFIYIVENQEIFVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDL
                     LLYKILDQGRYNVDGPLVLARYLLGCEFEVKNLRMIISALQNTIPFGSIKERIRPHYG
                     S"
     gene            3207..3527
                     /locus_tag="VQT46_001961"
     CDS             3207..3527
                     /locus_tag="VQT46_001961"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HET2371920.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            3590..5365
                     /locus_tag="VQT46_001962"
     CDS             3590..5365
                     /locus_tag="VQT46_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HET2371921.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTIAIGQKVSTGDILGTVKETEVVNHKIMVPYGVSGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFSNVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQVLGIPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGIYIDGKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSDNERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIMEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIHLILETGGL"
     gene            5366..6751
                     /locus_tag="VQT46_001963"
     CDS             5366..6751
                     /locus_tag="VQT46_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HET2371922.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLSSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVRFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            6774..7385
                     /locus_tag="VQT46_001964"
     CDS             6774..7385
                     /locus_tag="VQT46_001964"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HET2371923.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNRLRKEVESYLIDNLKSFAVAKSLKNSLMVEELFSIPSKEIELFIEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            complement(7496..>7652)
                     /locus_tag="VQT46_001965"
     CDS             complement(7496..>7652)
                     /locus_tag="VQT46_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HET2371924.1"
                     /translation="YSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERT
                     KFVLSRA"
BASE COUNT         2508 a         1067 c         1559 g         2518 t
ORIGIN      
        1 ataaaagtta tggatgagcg ttttggacat tctatttata tttatgaatc ggaaacattg
       61 tcggataatc aagatgaaat acctatcaaa ttaacgaatc attctttaat tgaaccattt
      121 gaattattga cagaaatgta tgctctgccc aaatattatg agaaagatcc tacacctgta
      181 ttagcaccat tttactttac attttttgga atgatggttg ctgatttagg ctatggttta
      241 ctattgtttt taggaacaat gttagcatta aaaatttttc atctaccttc agaaactaag
      301 agatttttaa aattctttaa tatattaggg gtagccgttg caatttgggg tggaatctat
      361 ggctcatttt ttggatatga gttgccattt catctgatat ctacaacctc tgatgtcatg
      421 attatattag tagtgtcagt tgtgtttggg tttattacag tatttgcagg tttgttagct
      481 tcaggactac aaaaagtaag aatgaagaaa tatgcagaag catataattc aggatttgtg
      541 tggtgtgtta ttctgcttgg cttgttattt attgctgtcg gaatgttgat gcctgatatg
      601 agactgttat ttgtattagg gaaatgggta tctattttta atgctgtggg aattttggtt
      661 gtttctatta ttcaagccaa aagcttgtca ggtattggag caggattgtt taatctatat
      721 aacatttcat cttatatagg tgatttagtt agtttcactc gattgatggc attaggatta
      781 tctggagcaa gtatagcatc agctttcaat ttaattgttg gtttgtttcc gggaacattg
      841 gctaaactaa caattggatt agtattattc attcttttac atgcgatcaa tatttttcta
      901 tcgttactat caggatatgt tcatggagca cgtctgatat ttgttgaatt ttttggtaag
      961 ttttatgagg gtggaggaaa accatttcaa cctttgaagg cttctgagaa atatattaag
     1021 gttattacaa agaattaatg gaggatatat ataatggaac atttagcaac ttatttttca
     1081 acctatggag gagctttctt cgctgcattg ggaattgtat tggcggttgg attaagtggt
     1141 atggggtctg cttatggagt tggtaaggct gggcaatctg ccgcagcttt actgaaagaa
     1201 cagccagaaa agtttgcctc tgctttgata ttgcaattac tgcccggaac acaaggatta
     1261 tatggttttg ttattggaat tttgatttgg ttgcaattaa ctccagaact tcctttagaa
     1321 aaaggcgttg cttatttctt tgtagctctt ccaattgcta ttgtaggata cttttcggct
     1381 aagcatcaag gaaatgtagc agtagcggga atgcaaatct tggctaaaag accaaaagaa
     1441 ttcatgaagg gagcaatttt ggctgccatg gtagaaacct atgcaattct tgcctttgtc
     1501 gtatcattca ttttgaccct tcgtgtataa gaaattaatt tgctattcaa aggaggtgtc
     1561 taaatgagca atttagaaaa cttacgagag tctgttattg aacaagctca tgaaaaaggg
     1621 cgtatgaaat tattggattc caaaaagaag attgatgatg aatttgaaat gcaaaagtcg
     1681 gtcattgtaa agaaaaaaga agtggaacat gaacgaaagt taaaagaatt acaacagaaa
     1741 tatcaaataa tttttcaaca attaaaaaat aaggaacgcc aatcaacgtt agtatcaaaa
     1801 cagaaaatat taaaagaact ttttcaatct gctttaatag aaatggaatc ttggagtgca
     1861 gataaagaaa tggagttcat ctatcgaatt ctggaacgat attcacaaca agaggtcata
     1921 gtaacttttg gggagcggac tttagctaaa ttcaatctgg aacaattaga gaaattgaaa
     1981 ttctcttttc caaatcattt atttagtgaa cagcctatct caaatgaatc aggcttactt
     2041 atttcaatag gtaaaattga tgataactat ttgtataaaa cattaattgg atcgatttct
     2101 aaggaagaaa gttcaagtat cgcaaatcaa atttttatca attaaggatg aaattggtta
     2161 atccttctta gaaatttgga gtattccaat aaaattagaa aggtatttta tggatactaa
     2221 tcttttttca aaaataaata cgacgatttc ggtaaaagaa aacgatttta ttacagaaga
     2281 taaatttcaa aaaattatac aatccaaaga tacggagaca atggcattta tcttagaagc
     2341 aactccctat catttatcga ttgacgtttt agaaaatcct agtcagacag agacttcgct
     2401 aatgacaaaa ttagtcaatg attatagatg ggcctatgct gaaagtccgt ctaataaaat
     2461 tgtgacttta tttgctttac gatatgttta tcataatatc aaagttttat taaaatctaa
     2521 ggcggcaatt aagaaagatt tttctaaatt attaattcca atagggattt ttgatataga
     2581 aagtttaaaa catttagttt cttccttaca ttcagataca cttcctgatt ttatggttca
     2641 tgaagtagaa tcaatttgga atgagtatga aacttttaat aatattcgtg tacttgatgt
     2701 cggagctgat ctagcatatt ttaaacatct gaaactttta tctaatgagt tagatgaggt
     2761 gctgtctcag gttattgtcg caatgattga cttttataat attattactg taaaacgtgg
     2821 tttatctcaa aataagagtc atggggatat tttacaatta ctttcagatg aaggaagtat
     2881 ttctgctaaa gaatttatat acattgtaga aaatcaagaa atatttgtgt ggttcaataa
     2941 aataaatcca agcttagatt caatcttttc aacttatgaa ttgaagatgc aggacgcaac
     3001 aatttcatct tctgagttag aatttttatg tgatttatta ttgtataaaa ttttagatca
     3061 aggaaggtac aatgtagatg ggccgttagt acttgctaga tatttattgg gatgtgagtt
     3121 tgaagtaaag aatctcagaa tgattatatc agctcttcaa aatacaattc cctttggatc
     3181 aataaaagaa aggatacgcc cgcattatgg aagctaataa gtataaaatt ggcataattg
     3241 gtagccgtga tattatttta ccctttagca tgattgggtt tgatatattt cctgcctatc
     3301 aagaacaaga agctataaat actctaagaa aattagccca atctgattat ggtgtcattt
     3361 atatcactga agacattgct tcaatgatat tagatacaat tcgccattat gattctcaag
     3421 ttgtgcctgc tattatttta ttaccgactc ataaacaagg tttaaattta ggattaaaac
     3481 gtatagagga taatgtggag aaagcagtag gacacaatat tttataataa tgtacaaaat
     3541 tgtctgtaat attattctat aatttttgga cttagtaagg agaataactt tgactcaagg
     3601 gaagattata aaagtatcgg gacctctagt tattgcatca ggtatgcagg aggctaatat
     3661 tcaagatatt tgccgtgtag gtaagctagg gttaatcggt gaaattattg aaatgagaag
     3721 agatcaggca tctatccaag tctatgagga aacatctggt cttggtccgg gagaacctgt
     3781 tgttacaact ggagaacctc tctcggttga attaggacca ggattgattt ctcaaatgtt
     3841 tgatggcata caacgcccat tagatcgatt taaattggct actcataatg attttctagt
     3901 tcgtggggta gaagttccaa gtttggatag agatattaag tggcattttg attccactat
     3961 agcaattggt caaaaagtga gtacgggtga tattctagga actgtcaagg aaaccgaggt
     4021 agttaatcat aaaattatgg ttccttatgg agtatctggc gaagtcgttt ctatcgcatc
     4081 tggcgatttt acaattgatg aagttgtata tgaaataaaa aaattggacg gtagtttcta
     4141 taaaggaacg cttatgcaaa aatggcctgt tcgcaaggcg cgtcctgttt ctaaacgttt
     4201 aatcccagaa gaaccattaa tcacaggtca acgagttatt gatacattct ttccagtaac
     4261 caaaggggga gcagcagctg ttcctggacc gtttggagca ggaaagacag ttgtacaaca
     4321 ccaagtagct aaattttcca atgttgatat tgttatttat gtcggttgtg gagaacgtgg
     4381 aaatgaaatg acggatgtac tgaatgagtt tcctgagttg attgacccta ataccggaca
     4441 atcaattatg caacggacag ttctgattgc taatacttca aatatgcctg ttgctgctcg
     4501 tgaggcttca atttatacag gaattaccat ggctgagtat tttcgtgata tgggctactc
     4561 tgtcgccatt atggctgatt cgacttcacg ttgggcagaa gcactacgtg aaatgtcagg
     4621 acgtctagaa gaaatgcctg gtgatgaggg ttatcctgct tatctgggaa gtcgtatcgc
     4681 tgaatattat gaaagagcgg gacgttctca ggttctaggg attccagaac gtgaaggaac
     4741 tattactgct attggagctg tatcgccacc cggtggagat atttcagaac cagttactca
     4801 aaacacttta cggattgtga aagttttttg ggggcttgat gctccgttgg cacagagacg
     4861 tcattttcct gcaattaact ggcttacatc ttattcactc tataaagaca gtgtgggaat
     4921 ttatatagat ggtaaagaga agacagattg gaatagtaaa ataactcgtg cgatgaacta
     4981 cttacaacgg gaatctagtt tagaggaaat tgttcgtctt gttggaattg attctctgtc
     5041 tgataatgaa cgactaacga tggaaattgc taaacaaatt cgagaagatt atttgcaaca
     5101 gaatgctttt gattcagtag atacattcac ttcgtttgca aaacaagaag caatgctaag
     5161 taatatccta acttttgctg atcaggcaaa tcatgcttta gagttaggtt cttactttac
     5221 agagattatg gaaggtaccg tggcagttcg agaccgtatg gcgcgaagta aatatgtttc
     5281 agaagataga ttagatgaaa tcaaaattat ttcaaatgag attacacatc aaattcattt
     5341 gatattagaa acaggaggtc tataaatgag tgttataaaa gaatacagaa ctgctagtga
     5401 agttgttggg cctcttatga ttgttgaaca agtaaataat gtgtcttaca atgagttagt
     5461 tgaaattcaa cttcataatg gagaaattcg tcgtggacaa gttttagaga ttcacgaaga
     5521 taaagcaatg gttcaacttt ttgaaggatc tagtggaata aatttagaaa agtctaaaat
     5581 tcgttttgct ggtcatgcac tagaattggc tgtatctgag gatatggttg gtcgtatttt
     5641 taatgggatg ggaaaaccaa ttgatggtgg accagattta attccagaga aatatttaga
     5701 tattgatggt caagctatta atcctgtatc tagagattat ccagatgaat ttattcagac
     5761 agggatctcc tctattgatc atttgaatac tcttgtacgt ggtcaaaaat taccagtatt
     5821 ttcaggttcg ggcttacctc ataatgaatt agcagctcag atagcaagac aagcgactgt
     5881 tttaaattct gatgaaaatt ttgcggttgt atttgcagca atgggtatta cttttgaaga
     5941 agctgagttt tttatggaag aactcagaaa aacaggagcg atcgatcgtt cagtcttatt
     6001 tatgaacttg gcaaatgatc ctgcaattga gcgtattgca actccccgca ttgctttaac
     6061 cgcggcagag tatctagctt ttgaaaaaga tatgcacgtt ctagttatca tgacggatat
     6121 gactaactat tgtgaagcgt tacgtgaagt ctcggcagcg cgccgtgaag ttccaggtag
     6181 acgaggctat ccgggatatt tatatacaaa tttatcaact ctatatgaaa gggctggtcg
     6241 cttagttggt aaaaaaggtt cagtgacaca gattcctatt ttaacaatgc cagaagatga
     6301 cataacacat ccaattcctg atttaactgg atacattact gaagggcaaa ttattttgtc
     6361 tcatgagttg tataatcaag gttatcgtcc accaatcaat gttttatctt ctctctctcg
     6421 attaaaagat aagggatctg gagaaggtaa aactcgtgga gatcatgctc caactatgaa
     6481 tcaactgttt gcagcctatg cccaagggaa aaaggttgaa gagttagcag tagtattagg
     6541 agaatcggct ttatctgatg tagataaatt gtatgtgaga tttacaaagc gttttgaaga
     6601 agagtacatc aaccaaggat tttataaaaa tcgaaatata gaagatacgt tgaatcttgg
     6661 gtgggaatta ctatcaattc ttcctagaac agagttaaaa cgtatcaaag atgatttgct
     6721 tgataaatat ttacctttgg tagaagttta atccagaaat ggagtgatta tctatggtac
     6781 gtttgaatgt aaaaccaact cgtatggaat tgaataactt aaaggaacgt ttgaaaacag
     6841 ctgaacgtgg acataagtta ttaaaggata aaagagatga attgatgagg cgatttattt
     6901 ctttgattcg tgagaataat cgacttcgga aagaagtaga aagttatcta attgataatc
     6961 taaaatcttt tgcagttgct aaatcattaa agaactctct aatggtggag gaattatttt
     7021 caattccatc gaaagaaatt gaattattta ttgagaaaga aaatatcatg agtgtaacag
     7081 ttcctagaat gcatatgaat attacttctc aaaatgagaa cagtgaatac agctatttat
     7141 cttctaatag tgaaatggat gatgtatttg ctacaatgaa tagtttaatt gataaattac
     7201 taagactggc agaagttgaa aaaacgtgtc agttaatggc tgatgaaata gaaaaaacac
     7261 gtagacgtgt aaatggttta gaatattcga ttattccaaa cttgtcggaa actattcatt
     7321 atatagaatt gaaactagag gaggcagaaa gagccaattt agttcgtatt atgaaagtga
     7381 agtagttcct ttatttagat ttttaattag atgaacaaat atcagcttgg ataaggcggt
     7441 aagcctttct aagctttttt aggctctttg tcaactgtag tgggttgaaa aaaagctaag
     7501 ctcgagaaag gacaaatttc gtcctttctt ttttgatatt cagggcgata aaaatccgtt
     7561 ttttgaagtt ttcaaagttc cgaaaaccaa aggcattgcg cttgataagt ttgatgagat
     7621 tattggtcgc ttccaatttg gcgttagaat ag
//
LOCUS       DAVAZV010000078         7474 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVAZV010000078 DAVAZV010000000
VERSION     DAVAZV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.078"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            60..929
                     /locus_tag="VQT46_001966"
     CDS             60..929
                     /locus_tag="VQT46_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2371925.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            933..1889
                     /locus_tag="VQT46_001967"
     CDS             933..1889
                     /locus_tag="VQT46_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET2371926.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKLPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            1889..2653
                     /locus_tag="VQT46_001968"
     CDS             1889..2653
                     /locus_tag="VQT46_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371927.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            2653..3363
                     /locus_tag="VQT46_001969"
     CDS             2653..3363
                     /locus_tag="VQT46_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET2371928.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKIPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            3828..4484
                     /locus_tag="VQT46_001970"
     CDS             3828..4484
                     /locus_tag="VQT46_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET2371929.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKIGILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDESIDLPALREKFEANGIQVEEIARTSAKVL
                     "
     gene            4592..5687
                     /gene="prfB"
                     /locus_tag="VQT46_001971"
     CDS             join(4592..4663,4665..5687)
                     /gene="prfB"
                     /locus_tag="VQT46_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET2371930.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            5705..6397
                     /gene="ftsE"
                     /locus_tag="VQT46_001972"
     CDS             5705..6397
                     /gene="ftsE"
                     /locus_tag="VQT46_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET2371931.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            6390..7316
                     /locus_tag="VQT46_001973"
     CDS             6390..7316
                     /locus_tag="VQT46_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371932.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
BASE COUNT         2208 a         1292 c         1682 g         2292 t
ORIGIN      
        1 agaacctatc aaaaagtgag ggaaaaccct cggaattata aatagaaaga gtgaatctta
       61 tgctccaaca actcgtaaat ggtttgattc taggtagtgt ttacgcgctg ttagccctag
      121 gatataccat ggtttacgga attatcaagc tcatcaactt cgcccatggt gatatttata
      181 tgatgggagc ctttatcggt tatttcttga tcaattcttt ccaaatgaat ttctttgtag
      241 cgcttattgt agctatgcta gcgacagcta ttcttggtgt cgtgattgag tttcttgctt
      301 accgaccttt gcgccactct actcgtattg ctgttttgat tacggctatt ggggtttctt
      361 tcctattgga gtatggaatg gtctatctgg ttggtgccaa tacccgtgcc ttccctcaag
      421 cgattcaaac agttcgatat gatttgggac caattagctt aacaaatgtg cagttaatga
      481 ttttggccat ttccttgatt ttgatgattt tgttacaagt cattgtccaa aagactaaga
      541 tggggaaagc catgcgtgca gtatcagtag atagcgacgc ggcgcaattg atggggatca
      601 atgtaaaccg tacgattagc tttaccttcg ctttgggttc tgctcttgcg ggtgcggctg
      661 gtgttctgat tgctctttat tataactctc ttgagccttt gatgggggtt actccaggtc
      721 ttaaatcttt cgttgccgca gtacttggtg gtatcggaat tattcctggt gcggctcttg
      781 gtggctttgt gattggtcta ttggaaacct ttgcgactgc ctttgggatg tcagatttcc
      841 gtgatgccat tgtttatgga atcttgttgt tgatcttgat tgtccgccca gctggtatcc
      901 ttggtaagaa tgtgaaagag aaggtgtaaa cgatgaagga aaatttaaaa gttaatattc
      961 tatggttact ccttttgtta gctggctata gcttgattag tgtactggtt tcagtcggag
     1021 tacttaatct attctatgta cagattttac aacaaattgg aattaatatt attttggctg
     1081 ttggtctcaa cttaatcgtt ggtttttcag gacaattttc acttggtcat gctggtttca
     1141 tggcgattgg tgcctatgca gcagctatta ttggttctaa attaccaacc tacggtgcct
     1201 tctttggagc tatgcttgta ggggctttgc tttcaggagc agttgcctta cttgtcggca
     1261 ttccaacctt gcgcttgaag ggggactatc ttgcggtagc aactctaggt gtttctgaaa
     1321 ttatccgtat ctttatcatc aatggtggaa gtcttacaaa tggtgcggca ggtatcttag
     1381 ggattcctaa ctttacaact tggcaaatgg tttacttctt tgtcgtgatt acaaccattg
     1441 caaccttgaa cttcttgcgt agcccaattg gccgttcaac cctctctgtt cgtgaagatg
     1501 aaatcgctgc tgagtcagtt ggggttaata cgactaaaat taaaatcatc gcttttgtct
     1561 ttggtgccat tactgcaagt attgctgggt cacttcaggc aggatttatc gggtctgttg
     1621 taccgaaaga ttacaccttc attaactcaa tcaacgtttt gattattgtt gtatttggtg
     1681 gactcggttc cattacaggt gcgattgttt cggctattgt tctgggaatt ttgaatatgc
     1741 ttctccaaga tgttgctagt gtgcgtatga ttatttacgc tttagccttg gtattggtaa
     1801 tgattttcag accaggtgga ctccttggaa cgtgggaact gagcctatca cgtttcttta
     1861 aaaaatctaa gaaggaggaa caaaactaat ggcattactt gaagtaaaac agttaaccaa
     1921 acattttggt ggtctaacag ctgttggaga tgtgactctt gaattgaacg aaggggaact
     1981 ggttggatta atcggtccaa acggagctgg gaaaaccacc cttttcaacc ttttgaccgg
     2041 tgtttatgaa ccaagcgagg gaacagtaac cctagatggt caccttttga atgggaaatc
     2101 accttataag attgcctctt tgggacttgg acgtactttc caaaatatcc gtctctttaa
     2161 agatttaaca gttttagata atgttttgat tgcttttgga aaccatcaca aacagcatgt
     2221 ttttactagt ttcttacgct taccagcttt ttacaagagt gaaaaagaat taaaggctaa
     2281 agctttggaa ttgttgaaaa tctttgattt agatggtgat gcagagactc ttgctaaaaa
     2341 tctttcctac ggacaacaac gtcgtttgga aattgttcgt gcccttgcta cggaacctaa
     2401 aattctcttc ttagatgaac cagcagcagg tatgaaccca caggaaacag ccgaattgac
     2461 tgagttaatt cgtcgtatca aagatgaatt taagattaca atcatgttga ttgaacacga
     2521 tatgaatctg gtcatggaag taacagaacg tatctacgta cttgaatatg gccgtttaat
     2581 tgctcaagga actccagacg aaattaagac caataaacgc gttatcgaag cttatctagg
     2641 aggtgaagcc taatgtctat gttaaaagtt gaaaatcttt ctgtgcatta cggtatgatc
     2701 caagcagtcc gtgatgtaag ctttgaagtt aatgaaggag aagttgtttc ccttatcggt
     2761 gccaacggtg caggtaagac aactattctt cgcaccttgt caggtttggt tcgaccaagt
     2821 tcaggaaaga ttgaattttt aggtcaagaa atccaaaaaa taccagctca gaaaatcgtg
     2881 gcaggtggtc tttcacaagt tccagaagga cgccacgtct ttcctggctt gactgttatg
     2941 gaaaatcttg aaatgggagc tttcttaaag aaaaatcgtg aagaaaatca agctaacttg
     3001 aagaaggttt tctcacgctt tcctcgtctt gaagaacgta agaaccaaga tgcagctact
     3061 ctttcaggag gggaacaaca aatgcttgcc atgggacgcg ctcttatgtc aacaccaaaa
     3121 cttcttcttt tagatgaacc atcaatggga cttgccccaa tcttcatcca agagattttt
     3181 gatatcattc aagatattca gaagcaagga acaaccgtcc tcttgattga acaaaatgcc
     3241 aataaagcac ttgcaatctc tgaccgagga tatgtattgg aaacaggaaa aatcgtccta
     3301 tcaggaacag gaaaagaact cgcttcatca gaagaagtca gaaaagcata tctaggtggc
     3361 taaaacaatc cagtggattg ttttagtcgg cagatgaaga ttacgaagta atcatcaata
     3421 tagtccgggg gcccttttta gtcggtagat tgagattgcg aagcaatcat caaatccaga
     3481 ggattgtttt agccggcaga taaagattac gaagtaatca tcaatatagt ccgggggccc
     3541 tttttagtcg gtggatgaag attgcgaagc aatcatcaaa tccagaggat tgttttagcc
     3601 ggtagattga gattgcaaac aaatctgcat ctacattgaa agcttaattt ctaataattg
     3661 aaaaaatcga atgaaaagtt tcttaccttc attcacagag ctcgatttta gagctctttt
     3721 tgctagctta ttcatacttt tctaaatttt gaaaaagaaa tgtaagcgtt tgatagattt
     3781 gcaaaaagat tgtataatag ggataagaat agaaaaggag aagtctcatg gcagttaaag
     3841 attttatgac ccgcaaggta gtttatatta gtccagatac aacagtatct catgcagcag
     3901 atttgatgag agagcaaggt ttgcaccgtc tgcctgttat cgaaaatgat caattggttg
     3961 gtttggtgac tgagggaacc attgcacaag caagtccatc taaagcaaca agtctttcta
     4021 tctatgagat gaattatctt ctgaataaga caaaagtaaa agatgtcatg attcgcgatg
     4081 ttgtcactgt ctcaggctat gctagtctag aagatgcaac ttatctgatg ttgaaaaata
     4141 agattggtat tctccctgtc gtagataacc atcaagtata cggagttatt actgaccgtg
     4201 acgttttcca agcctttctt gaaattgcag gttatggcga agaagggatt cgtgtacgct
     4261 ttgttacaga agatgaagtt ggtgttcttg gaaaaattgt ttctttgatt gtagaagaaa
     4321 atttgaatat ctcccataca gtcaatattc cgcgtaagga tggtaaggtg attatcgaag
     4381 tgcaaatcga tgaatcaatt gatttaccag ccttgagaga aaaatttgaa gcaaatggta
     4441 ttcaagtgga agaaatcgct cgcacttcag caaaagtctt gtaagaaggg aagtccaaag
     4501 gcttcttttt tcatgaaaag gggattagag caaaagatgg aaagaaatga taaaatatgc
     4561 tataatgaaa taatgtaaaa aaggagtatt tatggacatt tcagtaattc gtcagaaaat
     4621 tgacgcaaat cgtgaaaaat tagcttcttt cagggggtct ctttgacctc gaagggctag
     4681 aggaagagat tgccatcttg gaaaacaaga tgacagaacc tgatttttgg aacgataata
     4741 ttgcggccca aaaaacgtcg caagaattga atgaattaaa aaacacttac aataccttcc
     4801 ataagatgga agagttgcag gatgaagtcg aaattttatt ggattttttg gctgaagacg
     4861 agtcagtgca tgatgaactg gtagcgcagt tagccgaact tgataagata atgaccagct
     4921 acgagatgac tctactcttg tcagaacctt atgaccacaa caatgccatc ttggaaatcc
     4981 atccaggttc tggtggtact gaggcgcagg actggggtga tatgttgctt cgtatgtata
     5041 ctcgttatgg taatgctaaa ggctttaaag tggaagtgtt ggattaccaa gcaggtgatg
     5101 aggctggtat taagtcggta actttatcat ttgaagggcc taatgcctat ggtctcctca
     5161 agtcagaaat gggtgttcac cgcttagtgc gaatctcacc atttgactct gccaaacgtc
     5221 gccatacctc tttcacatct gtagaagtga tgccagaatt ggatgatact attgaagtgg
     5281 aaatccgtga agatgatatc aagatggata ccttccgttc aggtggtgcc ggtggacaaa
     5341 acgtcaataa ggtttcaaca ggtgtacgtt taacccacat tccaactgga attgttgtcc
     5401 aatcaacagt ggatcgtacc cagtatggaa atagagatcg tgccatgaag atgttgcagg
     5461 ctaagctcta tcaaatggag caagataaga aggctgcgga ggtagattct ctcaaaggtg
     5521 agaaaaagga gatcacttgg ggaagccaaa tccgttctta tgtcttcacg ccttatacta
     5581 tggtaaaaga tcaccgaact agctttgagg ttgctcaggt agataaggtt atggatgggg
     5641 acctagatgg ttttatagat gcttatctca agtggcgaat tagctaagat agaaaggaac
     5701 tcacatgtca attattgaaa tgagagatgt cgttaaaaaa tacgacaacg gaacgactgc
     5761 tctacgcggt gtttcggtca gcgttcaacc gggggaattt gcttacatcg taggaccttc
     5821 aggagcaggg aagtcaactt ttattcgttc tctgtatcgt gaagtaaaaa tcgataaagg
     5881 aagtctatca gttgctggtt ttaatctggt taagatcaaa aagaaagatg tcccgcttct
     5941 acgtcgtagt gttggggttg tcttccaaga ttataaattg ttaccaaaga aaactgtcta
     6001 tgaaaatatt gcttacgcta tggaagtaat cggggaaaat cgccgtaata tcaaaagacg
     6061 agtgatggaa gttttggact tggttggatt gaagcataag gttcgttctt tcccaaatga
     6121 actctcaggt ggggagcagc agcgaattgc gattgcgcgt gcaattgtaa ataatcccaa
     6181 agtattgata gctgatgagc caacaggaaa tctggatccg gataattcat gggaaattat
     6241 gaatctcttg gaacggatta acctacaagg gacaactatt ttgatggcga ctcataatag
     6301 ccagattgta aataccttgc gccaccgtgt cattgccatt gaaaatggcc gtgtcgttcg
     6361 tgacgaatca aaaggagagt atggatacga tgattagtag attttttcgc catttatttg
     6421 aagccttaaa aagtttgaaa cgaaatggtt ggatgacagt agctgctgtc agttcagtca
     6481 tgattacttt gaccttggtg gcaatatttg catctgttat tttcaataca gcgaaactag
     6541 ctacagatat tgaaaataat gtccgtgtag tagtttatat ccgaaaggat gtggaagata
     6601 atagtcagac aattgaaaaa gaaggtcaaa ctgttacaaa taatgactac cacaaggtat
     6661 atgattcttt gaagaacatg tctacggtta aaagtgttac cttttcaagt aaagaagaac
     6721 aatatgaaaa attaaccgag ataatgggag ataactggaa aatctttgaa ggagatgcca
     6781 atcctctcta tgatgcctat attgtagagg caaacactcc aaatgatgta aaaactatag
     6841 ccgaagatgc taaaaaaatt gaaggtgtct ctgaggttca agatggcggt gccaatacag
     6901 aaagactctt caagttagct tcatttatcc gtgtttgggg actagggatt gctgctttgt
     6961 taatttttat cgcagttttc ttgatttcaa ataccattcg tattaccatt atttcccgca
     7021 gtcgcgaaat tcaaatcatg cgcttggttg gagctaaaaa cagttatatc cgtggaccgt
     7081 tcttgttaga aggagccttt atcggtttat tgggagctat cgcaccatct gttttggtct
     7141 ttattgttta tcaaattgtt taccaatctg tcaacaaatc gttggtaggg caaaatctat
     7201 ccatgattag tccagattta tttagtccgt tgatgattgc cctactattt gtgattgggg
     7261 ttttcattgg ttcattggga tcaggaatat ccatgcgccg attcttgaag atttaggtaa
     7321 aatagctgct tttatgagga gattgtaaaa tctccttttt tgctacaaga gtttttgaaa
     7381 agagatgcgt agaagaaaag agcttccaaa gaagtccccc agagaagact tcttgatggc
     7441 taatttgaac ttgaaatttg gcgcactaga aatt
//
LOCUS       DAVAZV010000079         7220 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVAZV010000079 DAVAZV010000000
VERSION     DAVAZV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7220
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.079"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            231..645
                     /locus_tag="VQT46_001974"
                     /pseudo
     CDS             231..645
                     /locus_tag="VQT46_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720030.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(684..1127)
                     /locus_tag="VQT46_001975"
     CDS             complement(684..1127)
                     /locus_tag="VQT46_001975"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET2371933.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(1157..3379)
                     /locus_tag="VQT46_001976"
     CDS             complement(1157..3379)
                     /locus_tag="VQT46_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET2371934.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            3790..4032
                     /locus_tag="VQT46_001977"
     CDS             3790..4032
                     /locus_tag="VQT46_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371935.1"
                     /translation="MTRFEEIFEEYKNPQDTFFYPLVYKENTYEKTAISIFALLMLGV
                     CCLFLFSQQSYKKLVQYYANDQNLPSRITYSEYSDK"
     gene            4372..5001
                     /locus_tag="VQT46_001978"
     CDS             4372..5001
                     /locus_tag="VQT46_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET2371936.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQT46_001979"
     CDS             complement(5124..7016)
                     /gene="pepO"
                     /locus_tag="VQT46_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET2371937.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
BASE COUNT         1985 a         1681 c         1378 g         2176 t
ORIGIN      
        1 ttatcatttt atgacaaaca tactatcgtt aaatgctgat ttaatcgaaa ttttgagtta
       61 taaactcctc agtttcgaac tcaaaattag ccgtgcagga taggataccc ttcataaact
      121 tatataacta ctttaatacc ttaaaaagct aataaaataa ggaatatcta agcaatatac
      181 attctaaaat acctgtacgg gagtgtctct aaagaaaagg aggttttagc atgaaaaaaa
      241 tcatcttcat caaaaccatt caactccttg tcattgatgg aatcatgctg gcatttttga
      301 catttaaaag gggggcttac ttgggactgg attttgattt atagtggttg gctcattttc
      361 tttcatcctg tgctattgac ctatctttca aaccaacttt gtgaccactt tagtcaactc
      421 tattcccaga ttagaccgag attctggcgt tttgctttac aaattctcct atgggatagc
      481 ctgatgattc tctccttggt gtctttaagt gatattccac ttttccttca gggaactctc
      541 ctcatcctag gacatctcat cccttcctat cgcatctgcc aaagcctgaa aagagacttc
      601 ccccaagcat atcaagaacc gatttctttt tggagtattt tatgatcgat gagaaagacc
      661 aagccgactg ggcttggtct ttcttatctc tttttagtat ctaggataat ggtaacaggt
      721 ccgttattaa ccagctcaac ctgcatatct gctccaaaga tacctgtctg aacgggcact
      781 tcttgcgcta atttttgatt gaaagcatca tagaagtctg atgccatatc aggtttagct
      841 gcccctgtaa aggctggacg attgcctttc ttagtatccg caaagagggt aaactgagaa
      901 atagagagga tttctccttc aatatctttg acagacaggt tcatcttgcc ttctgcgtct
      961 gaaaaaatcc gcatattgac cagttttctc acagcatagt ccaaatcttc ctcttggtcc
     1021 tctggtccaa caccaaccag caataaaagt ccctgattga tttttccctg aatctggcct
     1081 tctatactca cttgggcttt tttaacccgt tggataatga ttttcataat agcctttcta
     1141 gtaagagcta ggacaactag ccgttggtcc gtttgacaga gtaaacttct ggcacactct
     1201 taattttatc gacaaccgtg gtcagtgtag agaggttggc aataccgaag gacacatgga
     1261 tattagcaaa cttcatatcc ttggttggtt gggcattgac cgttgaaata ttcttggttg
     1321 tatttgaaag aacttgcagt acatcgttca acagtcctgt acggttgaga ccgtagatat
     1381 cgatatgggc catatactcc ttatttgagc tagagtactg gtcttcccat tccacatcaa
     1441 ggagacgttg ctcgtagttt tcttgggcac gcaggttcat acagtccaca cggtgaatag
     1501 ccacaccacg acccttggta atgtagccaa caatatcgtc accaggcacg gggttacaac
     1561 acttagcaat ccgcactagg agaccagaag caccttcaat aaccactccc ccctcatgct
     1621 tgaccttgag agtttcttta ttttcaacct tgacctcgcc acctttgaca agctcctctg
     1681 cctcagcctt ggccttggca cgctcttcct cacggcgttc cttttcagtc agacggttaa
     1741 agacggtaat cgcaccgatt tccccaaaac caatggccgc aaagagggag tcttctgtct
     1801 tgtaactggt cttttgcaga acttgatcca tgtggcgctt gtccataaat ttatttgcca
     1861 catagccatt ttcttggaac tgagccatca gcatctcacg acccttgttg acagacaatt
     1921 ccttatcttg gtttttaaag aactggcgaa tcttattgcg cgccttgcta gtcttgacca
     1981 tattgagcca gtcacggcta ggtccaaagg agttcgggtt ggcgataatt tcaacctgat
     2041 cccctgtctt taacttggtt gtcagtggaa ccatgcggcc attgaccttg gcaccagttg
     2101 ctttttcacc gaccttggta tggatttcgt aggcaaaatc aatcggtcct gaatctttgg
     2161 gaagagaacg gacagctcca tctggggtaa aaacgtaaat ctcctcagcc agatagtttt
     2221 ccttaacaga gtccacaaat tccttagcat catcagcctg gtcttggagc tccatcatct
     2281 ccttgatcca gttcattcca atagctgatt ccttgctgtt aacttgcccc tttatacctt
     2341 tcttataagc ccagtgagcc gcaaccccgt actcagccac ctcgtgcatt tccttggttc
     2401 gaatctggaa ttcaatcggc ccttttggtc cataaacagt cgtatggata gactgataac
     2461 cattagcctt gcggttggca atatagtctt tgaagcgacc tggcatcggt ttccaaaatt
     2521 catgcacgta accaagcatg gcataaacat cactttgggt atctaaaata caacgaatag
     2581 caatcagatc atagatttcc tcaaaccgtt ttctcttgtc ctgcattttg cggaaaattg
     2641 agtaaatatg cttgggacga ccataaatct tccctttcaa gtgacgttct gtcgtatact
     2701 cctctaattt tgtgactacc tcatccacca aggcctcacg ctccctgcgc ttttccttca
     2761 tcatatgggt aatcttgtaa aactccgttg gattgagata acggaaagac aagtcttcta
     2821 attcccattt gacactggaa atccccaaac gatgggcaag cggggcatag atttccatgg
     2881 tttctttgga aatacgctcc tgcttgtctt ttcgaagatg tttcagggtc cgcatattgt
     2941 gcaagcggtc agacagtttg accaaaataa cgcggatgtc ctcagacatg gccatgagca
     3001 tcttgcgatg attttccgct aattgctcct cgatcgattt gtactcgacc ttgccaagct
     3061 tggtaactcc gtcaacaatc atccgcacat caggaccaaa ctctctttcc aaatcgtcca
     3121 aagtcgcatc tgtatcttcc accacatcat gcaagaatcc acaagctact gttacagcat
     3181 ccagctttag cttagctaaa atacctgcca cttggatagg gtgaatgata taaggctcgc
     3241 ctgatttgcg atattgacca ctgtggcatt caacagcata gaccaaggcc ttatggacaa
     3301 aatgaacatc ctcttccgtt aaatattctt tggttaaagc gacaacttct tcgcctgtta
     3361 aattcacttc tttcggcatc tctactctcc aattcttcct accattttat cactttttta
     3421 agaatatgaa aactagattg gaacagaata agaaaaaaat aattcaaaat tgcttgataa
     3481 ttctgaatta ttggcccata atatactacg aagttagatt ttaaacttag gtgatagaag
     3541 gagagataga agaacggaaa ccatattgta acccaaagac tttctgattt ccccaattcc
     3601 attgaagata cgaaagataa acggtggaac tcgtatcaca tacactggta ccttgactgg
     3661 attttggaat taatactcaa tgaaaatcaa agagcaaact aggaaactag ccacaggttg
     3721 ctcaaagcac tgctttgagg ttgtagataa gactgacaaa gtcagtcaca tatatacggc
     3781 aaggcgacgt tgacgcggtt tgaagagatt tttgaagagt ataaaaatcc tcaagatact
     3841 ttcttctatc ctttagttta taaggagaat acctatgaaa aaactgctat ttctatcttt
     3901 gctctcctaa tgttaggagt ttgctgcctg ttcctattca gccagcaaag ctataaaaaa
     3961 ctcgttcaat actatgctaa cgaccagaac ctgcccagta ggataactta tagtgaatat
     4021 agcgacaaat gagaagccaa ctacggtagc actctaaaca tcacgtctat caaacaagct
     4081 aatgacggag tttatgcaac ctatgaaggg caattgacac ctttccaata ttgataaatt
     4141 gataaccagc ctgtcttcat ctagtcatgc tggtttttaa gttcatttta aatccttacc
     4201 tattctccct aactgtgcta tacttaattt atactcaatg aaaatcaaag agcaaactag
     4261 aaagctagcc gcaggctgtt caaagcactg ctttgaggtt gcagataaag ttgacgcggt
     4321 ttgaagagat tttcgaagag tattagtaca ttctttgaga ttggagttag tatgaaaatc
     4381 cataaaaccg tgaatcctgt tgcctatgaa aatacctatt atctagaagg cgaaaagcac
     4441 ctcatcgtcg tcgatcctgg tagtcattgg gaagccattc gtcagacaat cgagaagatc
     4501 aacaaaccga tctgtgctat tctcttgacc cacgcccatt atgaccatat catgagtctg
     4561 gacttggttc gcgagacgtt tggcaatcct cctgtctata tcgcagagag cgaagccagc
     4621 tggctctaca ctcctgtcga taatctctcc ggtctccctc gccacgatga tatggcagat
     4681 gtggtcacaa aacctgcaga acacaccttt gtctttcacg aagaatacca actagaggaa
     4741 tttcgtttta aggttctacc gaccccaggg cactctatcg gtggtgtttc cctagtcttt
     4801 cctgatgctc acctagtctt gacgggagat gctctattcc gcgaaactat cggacggacc
     4861 gaccttccga ctggtagcat ggagcaactc cttcatagta tccagaccca actcttcacc
     4921 ctaccaaact acgatgtcta tccaggacat ggtccagcta ctactatcgc tcacgaaaag
     4981 gccttcaatc cctttttcta gcaagatgat gacaatcgaa atttaagtaa actatccagc
     5041 aaatctttct attacaaaag gcatcctatc aaggttttca cacgtgattg gatgcctttt
     5101 ttctgatgac tagatttttt gtattaccaa ataatcacgc gctcctctgg tgaacgccac
     5161 attccgtctc cttctttgac atcataggtt gtaaagaaat cgtcgaagtt tggtacttgc
     5221 acattgacac ggagtttggc tggtgcgtgc acatcgacgc tagccaaaag tttcataaat
     5281 tctggtcgac ctttcatgcg ccagatgcga ccgaagttgt agaagaactc ttctgctgag
     5341 aagtctgctt ctctcttagc tgcttcaagc gctgctgcga ttcctcccaa gtcagccacg
     5401 ttttctgata cagtcaattt accgttaatg gttgctccat aagaatcctg tccatcaaat
     5461 tggtcaatga ctttttgtgt tttctccttg aaggcagcat agtcgctctc tgtccaccaa
     5521 tccttgaggc taccattttc gtcaaaggaa gccccgttag tatcaaaggc gtgggaaatt
     5581 tcatgggcaa tcactgcccc aataccaccg tagttagcag aagatgactg atgcaagtca
     5641 tagaaaggcg cctgtaaaat ggccgctgga aagacaatca ggttcttctg aggattgtag
     5701 taggcattga ccatatgagc aggcatgccc cattccttat agtctacagg ctggttccac
     5761 ttactccaac tgtgcttgat ttccacacgc gcaaaggcta gagcattctc aaaaagactg
     5821 gcagtttcat tcactacctt atccttgtaa cgtgcaggca attcttctgg atagccaata
     5881 taaggtttga tcacattgag cttcacgata gcctgtttac aggtttctgg agtgagccag
     5941 tcattcttaa gcagacgctc cttatagaca tcaatcatgg ttgccacttt tttctccaca
     6001 tccgccttgg cttctggaga gaacttctca cgggcgtacc aaagccccag ggcttgcttg
     6061 aaaggttcct gtgctagatg ataagctgct ttgaccttat cttttgcctc tggaactcca
     6121 gaaagggcac ggctgtaggc accagacaaa acacggatat cctctgttaa atagctggtt
     6181 gaaagattga caacactcaa aatcaaggtt gctttaagga gagaccaggc ttcctcactg
     6241 taaaattgct ctgctgcttg ccagaaacgt tcctcgtcta caataacctt gtctggtaat
     6301 tgcccaataa ctgctttgaa gaagtcatcc aaaggtaggg caggcgcgaa tttcttgaaa
     6361 tcttcgtaag aatatggatg atagagttta gcatattctg aactttcttc attagagagc
     6421 accactgccg caactcggcg gtccaattca agtctttttt ctagcaagtc ttcaatttct
     6481 tcatcagaga aatcataagc cttgaggaga tttgcgctgc tttctttcca aagagtcaag
     6541 agctcttcgc gctgaggatg ttcttctgca tagtaggtcg tatctggcaa gattgtgctt
     6601 ggagcgctag cccatagaac attgattcta gcatccataa agtctggcga tacaccaaaa
     6661 ggaaggaagt ttggttttcc tgcaagctca aactctgcta gtttagctgt aaaatccgca
     6721 aaagtttcca attcttggaa ttctttaagg agtggtaaga caggtgtgat accgtcagct
     6781 tctctcttgt caaaatcacg aactaggcgg tggtatttga caaagttttc caagatagca
     6841 tcctcaggca cttcttcacc tgctaaccac ttgtctgttg tcgccagcat caggtcttca
     6901 atttcctggt ctaaatcaac aaaacctcct gtttgagact tatctgctgg gatttcagct
     6961 gtctgttgcc attctccatt gatagcatca taaaaatcat cttgataacg tgtcatcttg
     7021 ttctcgcttt catttgtatt tgcatttatc ttaacaaaaa tcactaggga atgcaattaa
     7081 taaccattta actattattt tttagctatt ataaaaaacc tttccatgat aaaacgcata
     7141 attccaagtt ttttacactt gatactatgc gttttataat ttagaaattt atcctgaaag
     7201 ttatctttag aatctatttt
//
LOCUS       DAVAZV010000080         7162 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVAZV010000080 DAVAZV010000000
VERSION     DAVAZV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7162
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.080"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(741..1001)
                     /locus_tag="VQT46_001980"
     CDS             complement(741..1001)
                     /locus_tag="VQT46_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371938.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADIHRFVIELEPVKSTILQNDDISLDQNEIFEILKNFLDG"
     gene            complement(1060..1611)
                     /locus_tag="VQT46_001981"
     CDS             complement(1060..1611)
                     /locus_tag="VQT46_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371939.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIYEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            complement(1601..1798)
                     /locus_tag="VQT46_001982"
     CDS             complement(1601..1798)
                     /locus_tag="VQT46_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371940.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            complement(1802..2386)
                     /locus_tag="VQT46_001983"
     CDS             complement(1802..2386)
                     /locus_tag="VQT46_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371941.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEIPKELTPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            complement(2794..3219)
                     /locus_tag="VQT46_001984"
     CDS             complement(2794..3219)
                     /locus_tag="VQT46_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371942.1"
                     /translation="MTSRVFIDADCISAFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVTKGSAEIVSIDIGTEEYALYRDLTRNYDSNKIIGKGEATSIFLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            complement(3212..3706)
                     /locus_tag="VQT46_001985"
     CDS             complement(3212..3706)
                     /locus_tag="VQT46_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371943.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMVLGHYIKSTEQLLENNRISQGKYEELLLDAFRYDIVYGLDEEGE
                     LSFD"
     gene            complement(3752..3958)
                     /locus_tag="VQT46_001986"
     CDS             complement(3752..3958)
                     /locus_tag="VQT46_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371944.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            complement(3945..4106)
                     /locus_tag="VQT46_001987"
     CDS             complement(3945..4106)
                     /locus_tag="VQT46_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2371945.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQT46_001988"
     CDS             complement(4471..5427)
                     /gene="lytA"
                     /locus_tag="VQT46_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET2371946.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPEGLITVK"
     gene            complement(5803..7155)
                     /locus_tag="VQT46_001989"
     CDS             complement(5803..7155)
                     /locus_tag="VQT46_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET2371947.1"
                     /translation="MDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVGRFLGQE
                     SLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWILGALLSI
                     LVMLLGFLGLYHLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLRSIGDSL
                     AALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRKSVPELL
                     PQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQTAARRI
                     MTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIFLFFASP
                     ALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPLVSSFIE
                     LIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAILATKVQS
                     "
BASE COUNT         2298 a         1486 c         1132 g         2246 t
ORIGIN      
        1 tggtttcgca ggaagtctat tatatatgca cagacatatg aaatcttttt gagacagcag
       61 ttatgatata tttatccatt cacaacatct tctgtactaa tactacaata ttggtacatt
      121 ttgattacac aatcgtttca aaaaatatga tggaagcctg agtattttat agtaattccc
      181 ttcctatcaa ctagatcaac cagttgagtg ttgaatgttg aaacacccta gcctcagcaa
      241 aggactatga tcagcatttc ctagccaata ggacgctcca aatcacctat tctaagtcca
      301 tcactagctt ggtcagtaag atacagactg caaggcgaga ctgacgtggt tgatgagatt
      361 ttggaagagt attacaatca tagattcacc agtagacttg accgcagatt taactatagt
      421 agattgaaac tagaatagta catctctgct tctaaaacat tgttagaaat cgatttgact
      481 gtcctgatca atttgtcctg ttctcgtttc atttcactat actaaaaaac cacctgaaac
      541 aaatcaagtg actagaggat aaaaacaaag actaggcaaa aagttttgaa aagcaaaaaa
      601 cgcataatat caggtcttga aaaaccttga tactatacgt ttgattgtgg gaagattgac
      661 ttcattttct cctgaaattg aagttttttc tagtttccag atatagacga attcaatata
      721 gccatctcgc tacaattatt ttaaccatcg agaaaatttt tcagaatttc aaaaatttca
      781 ttttgatcca atgaaatgtc atcattttga agaatagttg acttcacagg ctctaattct
      841 atcacaaagc ggtgtatgtc tgcttttacc gcactacttg atgttatagc cgataacttt
      901 tcatctccta gcaaggaagc tgtcaaacgg gtaaggtcat tcaaatgctt tttaatggac
      961 ttacttaaac cttgagcacc tgtagcagag cgttccctca tatccagcca agctttagcc
     1021 ttaaaaataa ttaatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     1081 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     1141 agagtataaa ccacaattac tcaataccga atacccctga atggtttctt tttcatgcac
     1201 caatatatta taataatctt catccaataa taaggctgat aaactagcat cttggtcaaa
     1261 atgtaaggga atttctcgac cgtccttctt taatggatat tctggtaaga tactaaatag
     1321 ttcaatcata gaaggaaact caggattagt tgttgtaaat cgaaaaagct gcgctttctc
     1381 atctttctga cttccttgat actctcccaa ttctaaaaaa tgattcaagg tagtataaaa
     1441 ttccttattt tttacttcat aaatgatgac catatcataa tcttttgttg tgcgactttt
     1501 aaatccttgc gaatccaata cgatagaggt agcagttccc ccaatcagaa cataatagtt
     1561 ctgaaaatcc gcaaacattt cttgaaaaat aactttcgta ttagctggca tcatcttctc
     1621 ccagatactg taatatcata ttttctagtg cttcactctc ttcctctata cgtgggtcat
     1681 catcatcttt taaggtcaaa taaagagaaa tcggatctac aaattgttta tcatgattat
     1741 ttttaaaatc attccaaaac tcagatacaa aaggacgata tttccatatc tctagcatct
     1801 ttcattttaa aacatgctga gaaagtggca aggataactg attgaatttt ctctgccata
     1861 tgacatagct agtattttca tccgtttcag ctaaaaaagt tgaatgcgac aaagcataag
     1921 caccaccata tagaaggtta gaaacagatt ttatctgctt tatatcgcca tctggcaata
     1981 aaaaggcaat ccacgttaat tgttcgctag gtgttaattc cttagggatt tcagtatcat
     2041 tcgcattgag tactagtccc aatggaggga agaagaggtt tcccttaaag tctacaaacg
     2101 gaactctagc ttgaagtaat tgcttttttt cactgtctga taacttcgaa aacaccaaaa
     2161 caacatccat attggctttt tcacccatag tgcgagcctg agtaacaaat gaactcaaac
     2221 tcccccttct cttttcttta atcaataaaa atgattcctt atgaaaagtc atttgagtat
     2281 actcaaacct ttttacaaaa ctgattggta aagtcaaagt cagttcctca atactgacat
     2341 caacataaaa ggattgaaaa attgacatta tctttttgac attcatgttt tttccttatt
     2401 ctatcatttt tattatattt tatcattcgg tataataaaa tataagtttt ttgataaaat
     2461 aaccaaaaac tactcgctat cccctctcac attaccctac atatcgtttg acatgcgact
     2521 gatagttcag gaaaacttca aggagaactt ttctctcatc cactatgcag gacttactat
     2581 ttcacttcta ctcctatagg ctcaatttga cacttttctt tttcgaattg ctcatatgcc
     2641 tcctgaatag tgagttcgat ttatccaaat ttatttttgt ctattttgat gaatacttcc
     2701 acgaagatag tctgaaaatg aatttgcacc aattttcctt ctctttttaa gcatattatt
     2761 ccagatatga ttgccctctt gttcagtaat aaattacgct ttaaacgctt caatcagtat
     2821 atctcctgtt gtcatatgtt ctaaagaaaa ttcttctaca tatggtttaa catctcttag
     2881 gttattactt cctaatatcc cattatgctt tttcgctaag aaaatagaag tcgcttctcc
     2941 cttaccaata atcttgttac tatcataatt tcttgttaaa tctctatata atgcgtattc
     3001 ttcagttcca atgtctatgc tcacaatctc agctgaaccc ttagttacca actggtctat
     3061 cctagatttt aaatggggaa ttgtaggtat attgatttca tcatacacct cttgtggaat
     3121 aacaatttta cccgaataga gcttttctaa aagatgttca gtgccaaccc ataaaaatgc
     3181 tgaaatacaa tctgcatcaa taaatacacg actagtcaaa cgacaactcc ccctcttcat
     3241 ctagcccata tacaatatca tatctgaaag catctagtaa cagttcctca tacttccctt
     3301 gcgaaattct gttattttct aaaagttgtt cagtcgattt aatatagtgc cctaatacca
     3361 tttccttttt actttctgac aaaggacgat ataaacttgt atcatagcct aatcttgaag
     3421 ctgtctctat aacactaata tccatatttt taatttcttc tgcatcaagg tatccatcat
     3481 ttctcaatct atataacata gctttatgac tgataccata aaactgaccc aattttataa
     3541 tatcttctac ttcaagatga gttctattgg cattttctct gatttcctca accatcctat
     3601 acagtgaaga tgggaaaatt aaaaaataag aagcaaactg atccgctttt ctttcagttt
     3661 catctccttc accaatcaag ataagactga ctgaactctt cttcacctca tcataataaa
     3721 gatgatacag tccatgtgct aaagaaaatc tttaccttcc taatggcatg tctgaattga
     3781 ctgcaatgag actgaactga gttcctttat aacagactcc gctaatattc tttccgagtc
     3841 cataaaatac cagcgtcaaa ttttctatct tttgtaccaa tttaaaaata tctatcggcg
     3901 attcaccatc agctcccaac ttttttctaa gatttgaagc tttattactt aaatccattc
     3961 gtgatattcc tttcaccttt ttccattttg gcaatcatgc tttgattcaa agacaaatac
     4021 tcagcaatct tatcttgagt aagatttgaa gatattctaa gttcttttat tctttttcca
     4081 acatcacata catttatcat attcatacac ctctcataaa aagaatagca cattcttgtc
     4141 ataatttttt aaataaaaaa attatgacaa aacaaggaag caatttattg atgctactta
     4201 aaaatctaaa attgatgata ttaaacctat ttgatgagtt cctatcaaaa atcgtatctt
     4261 caacctcaaa acagtactta aagctatccg actcggttta cattgtcaaa tttagatttt
     4321 atttgagcat aactttctag tttgcttttt gatttttgtt taatatagta acaaaaattg
     4381 aaggaaatat ctccacaaga aaacgcatac tattaagctt tttcaagacc taataatatg
     4441 cgctgttctg atttgaaaga cattccatta ttattttact gtaatcaagc cttcaggctc
     4501 tactgtgaag tctggcttgt ctgccagtgt tccgtctggt ttgaggtagt accagcctgt
     4561 tccgtccgct gactggataa aggcatttga taccatggcg ccttctttag cgtctaagta
     4621 gtaccaagtg tccttgtact tgacccagcc tgtcttcatg gcaccttctt cgttgaaata
     4681 gtaccactta tcagcgattt tcttccagcc tgtagccatt tcgcctgagt tgtcgaacca
     4741 gtaccagttg ccgtctgtgt gcttcctcca gcggtctgca agcatatagc ctgaactgtc
     4801 aaagtagtac caagtgccat tgattttctc aaacttgtct tttggataag agccgtctga
     4861 atgtacgtac cagtagccag tgtcattctt ctgccagcct gtttcaatcg tcaagccgtt
     4921 ctcaatatca tgcttaaact gctcacggct aatgccccat ttagcaagat atggataagg
     4981 gtcaacgtgg tctgagtggt tgtttggttg gttattcgtg caatactcgt gcgttttaat
     5041 tccagctaaa ctccctgtat caagcgtttt cggcaaacct gcttcatctg ctagattgcg
     5101 taagagttcg atataaaggc ggtagtccgt catgaactct tctttggttg aatggctttc
     5161 aatcagttca accgctgcat aggtctcagc attccaaccg cccccaacgt cccaggcacc
     5221 attatcaaca ggtcctacct gcatgatgca accgttccca acaatgtgcg agaaaaaacc
     5281 taattctggg tctttccgcc agtgataatc cgcttcattc tgtacggttg aatgcggatt
     5341 cccagttgag tgtgcgtgta cttgcctata tggttgcacg ccgacttgag gcaaatctgt
     5401 tcttaattta ctcacattaa tttccatatt ctactcctta tcaattaaaa caactcattt
     5461 tttacaatcc agaaccagaa actcctttat ttctacctta caaagaagac aatcttagtc
     5521 acgattaagc ttgtagatag aacctcaaaa cgcactattt tgacactgta aataggactg
     5581 acaaggtctg cattctatct acaataacac cccagactaa aaagcttttc aaaagtatat
     5641 ttttacagtc tctatatgtc cttttcataa atactatact ttattatatc acataaaaga
     5701 agtcaaaagt ctgttaaact attttcaaca ccaaactaaa gaagagaaca caagtttttt
     5761 cgatgttcac tagaggaaat ggattttatt cagtaaatcc aactaggatt gcactttggt
     5821 tgccaaaatt gcctttcctt cttttatcaa gggatgacgg aatagtgaga agtacagttg
     5881 aactgtcatg gcaacccaga taagaggttc acaaaggata acacccttat atcctgccca
     5941 aggaataatc aaaaccacaa aaacgatttt tccgattagt tcaataaagc tagaaactag
     6001 aggaaggatc ttctgcccca agccctgcaa gcaattgcga taaatcaaca agaggctcaa
     6061 aatgggataa aaggctgaac tgatttgcag atagagactt ccattttcta tcaagtaacc
     6121 atctgtcgaa ctagccaaga aggaaaccaa ggctggactg gcaaaaaaga ggaaaataca
     6181 aacaaaaact gcccaggata tacttaaacg actgccgatt cgaagacctt gaacaatgcg
     6241 gtcaggtcgc ttagctccta gattctgaga agcaaaggtc gtcattgatg cagaaatagc
     6301 ggtcatagga agaagggcaa aggtcataat gcgtcgagct gccgtctggg cactaataat
     6361 cactgcacca aatgtattaa cagaaaactg taaaatcaca ctgccgatag atacaattga
     6421 actcatcaag cccatagcca aaccttgctc caagagatcc gcgtacaagc ttttgtccca
     6481 tttgaaatgt ttaaactgtg gcaagagttc tggcacactt ttacgaatat aataaaagca
     6541 gagaaccgct gataaacctt gcgaaataat ggtagcaagt cctgcggatt gaactcccag
     6601 atgcaattgc gtaataaaat agagatccag aaccacatta accaaggcag agaaaatcag
     6661 aaatcccagg gctgctagac tgtcaccaat agaccgcaac aagcctgcaa aaagattata
     6721 agcaaagctg acacctacac aggtcacaat catagaaata tattgataag attgaggaag
     6781 aatttctgca ggagtatcta agtattgcaa gagatgatac aagccaagaa agcccagcaa
     6841 cataactaga atgctcaaaa gagcacctaa aatccaagta gctgctactg cttccttgat
     6901 tttagtgaaa ttccgagccc cataataacg agcaatgaca atccccatgc cattgccaac
     6961 accaagtgta aaacctacaa tcaggtcaaa aatcgctgtc gtcgctccta ctgcagccaa
     7021 ggattcttga ccaagaaatc gtccaacaat caagacatca gcagtgttat agagctgttg
     7081 aaaaatattt gatagcaaaa ttggaaaggt gaagcttaag agcgagggaa gaatcggacc
     7141 atgtatcagg tccactgttc gt
//
LOCUS       DAVAZV010000081         6889 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVAZV010000081 DAVAZV010000000
VERSION     DAVAZV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6889
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.081"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..316
                     /locus_tag="VQT46_001990"
     CDS             <1..316
                     /locus_tag="VQT46_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2371948.1"
                     /translation="ELIAPMTYEETMTSDFFEVWFQKFFLPTLTTPSVIIMDNVRFHR
                     MGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWVHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            377..1339
                     /locus_tag="VQT46_001991"
     CDS             377..1339
                     /locus_tag="VQT46_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET2371949.1"
                     /translation="MNMSNITIDGQEMDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVIIFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1516..2523
                     /gene="gap"
                     /locus_tag="VQT46_001992"
     CDS             1516..2523
                     /gene="gap"
                     /locus_tag="VQT46_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET2371950.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFIKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2590..3426)
                     /locus_tag="VQT46_001993"
     CDS             complement(2590..3426)
                     /locus_tag="VQT46_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET2371951.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQYLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETYVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3552..5747
                     /locus_tag="VQT46_001994"
     CDS             3552..5747
                     /locus_tag="VQT46_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET2371952.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVAAVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYIMAGKTGTTEAVFNPEYTSDQWVIAYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5800..5952
                     /gene="rpmG"
                     /locus_tag="VQT46_001995"
     CDS             5800..5952
                     /gene="rpmG"
                     /locus_tag="VQT46_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET2371953.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            5962..6138
                     /gene="secE"
                     /locus_tag="VQT46_001996"
     CDS             5962..6138
                     /gene="secE"
                     /locus_tag="VQT46_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET2371954.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6194..6730
                     /gene="nusG"
                     /locus_tag="VQT46_001997"
     CDS             6194..6730
                     /gene="nusG"
                     /locus_tag="VQT46_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET2371955.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2143 a         1198 c         1495 g         2053 t
ORIGIN      
        1 tgaattaatc gctccaatga cttacgaaga gacgatgacg agcgactttt ttgaagtatg
       61 gtttcagaag tttttcttac caacattaac cacaccatcg gttattatta tggataatgt
      121 aagattccat agaatgggga agctagaact cttgtgtgaa gagtttgggc ataaactttt
      181 acctcttcct ccctactcac ctgagtacaa tcctattgag aaaacatggg ttcatatcaa
      241 aaagcacctc aaaaaggtat taccaagttg caataccttt tacgaggctc ttttgtcttg
      301 ttcttgtttc aattgactat atatcacgga tacagttggg aaagaagcta ttaaacattt
      361 ggagagtcct tttgggatga acatgtcaaa tattactata gatgggcaag aaatggatct
      421 gagtcaaacg atgccttctt atgctcaagt agtgagtctt tatgatgata caagtatctc
      481 tgttagtagt aatgagacgg acaaagtgtt ggctggctcc ctctatactg atacaaatga
      541 acagggatta acgattccaa gcagtttact aaaaaattgg aatgaacaga caggaaaaaa
      601 tttgacagct aatgatctta ttggcaaatc agtctcagcc agcattgtag aaagtgctgc
      661 cgaaactagt aagattgctc aatttcaaac gaagattgta cgtgtaatca atgatgaaga
      721 tgacatggag gacagcaaca gtttcatgct gtctcatcaa atggaaacga ttttgaaaga
      781 ggctggattt acgaaagctg tatcttattt tatcttggaa ctcaaagatc catcacagac
      841 aaaagtagta acagaagaat tacagaaaaa taagaagtat actgtgcttt ctcaacagag
      901 agttcttgat attgtgatta tctttattcg tgttattcag ggattattga ttgtgctttc
      961 atcacaagct attgtggtag cagcggttat gattggtatc attatttaca tcaatatcat
     1021 gcagcgttcc aaggaaatag gtgtcatgaa ggcagttggt tatcagaatc gtgatgtcaa
     1081 aggaattttt atttacgagg ctatctggat tgtaggcatc gccttgctgc tggcattttt
     1141 ggttgcacaa ggggtgggaa gtttggcgaa tgcgattgta agtcactttt acccatccat
     1201 cactaaagtt tttgaattaa atcttttatc tgttttagga actctagttt tcgctctatt
     1261 acttggttat gtctcagcct acttcccggc gcgtaagatt agtaaaatgg atcctgtaga
     1321 accgttacgc tatgaatagt aagggattcc ttgatttaca gtcttaaaaa gaaactaaca
     1381 tagaaaaaca atggacatac ttgcaattca actcaaatag ttgtataata ggtttgttga
     1441 aaggtgattt gtagtgattc aagttactct tttcacaata aaaatttcat gattttcata
     1501 aggaggaaat cactaatggt agttaaagtt ggtattaacg gtttcggacg tatcggtcgt
     1561 cttgctttcc gtcgtatcca aaacgtagaa ggtgttgaag ttacacgcat caacgacctt
     1621 acagatccag ttatgcttgc acacttgttg aaatacgaca caactcaagg tcgtttcgac
     1681 ggtactgttg aagttaaaga aggtggattt gaagttaacg gtaaattcat caaagtttct
     1741 gctgaacgtg atccagaaca aatcgactgg gctactgacg gtgtagaaat cgttcttgaa
     1801 gctactggtt tctttgctaa gaaagaagca gctgaaaaac accttaaagg tggagctaaa
     1861 aaagttgtta tcactgctcc tggtggaaac gacgttaaaa cagttgtatt caatactaac
     1921 cacgacgttc ttgacggtac tgaaacagtt atctcaggtg cttcatgtac tacaaactgc
     1981 ttggctccaa tggctaaagc tcttcaagac aactttggtg ttgttgaagg attgatgact
     2041 actatccacg cttacactgg tgaccaaatg atccttgacg gaccacaccg tggtggtgac
     2101 cttcgccgtg ctcgcgctgg tgctgcaaac atcgttccta actcaactgg tgctgcaaaa
     2161 gctatcggtc ttgtaatccc agaattgaat ggtaaacttg atggatctgc acaacgcgtt
     2221 ccaactccaa ctggatcagt tactgaattg gtagcagttc ttgaaaagaa cgttactgtt
     2281 gatgaagtga acgcagctat gaaagcagct tcaaacgaat catacggtta cacagaagat
     2341 ccaatcgtat cttcagatat cgtaggtatg tcttacggtt cattgtttga cgcaactcaa
     2401 actaaagttc ttgacgttga cggtaaacaa ttggttaaag ttgtatcatg gtacgacaac
     2461 gaaatgtcat acactgcaca acttgttcgt actcttgaat acttcgcaaa aattgctaaa
     2521 taattcttga gttgatagaa agcaaggctt tgtggtcttg ctttttatat ggaaaaatgg
     2581 atgacacgat catccattct tttttaattc tttttcaaat gtatttgaaa gggtagtgaa
     2641 agttagcttc tctaaagtaa gtgggtgggt aaaggaaagt cggaaggcat gaagcataag
     2701 ccgacttgtc tttgatttac tattatagag agggtcgccc aggataggaa gattatgatg
     2761 cgaaaggtgc acacgaatct gatgggttcg ccctgtcttt agcttgcaac gagccaagga
     2821 agtcttgttt gagaattgct ttaatctgct tacatacgtt tcagcatatt gcccattttt
     2881 tgcatcaact attctttttc tacgatcatg gcgatcacgt ccaattttgt ctctgaaaac
     2941 aagttctttt ctgttgatat ttccatcaac tagagcccaa tattctctag aaatctcttt
     3001 tttctccaat aagcgattga gaatgggcag gataaaagga tttttggcaa agagaactaa
     3061 gccactggtt tccatgtcca gacgatgaac gacatagcag gtttggccaa cataggtact
     3121 gacatggtta agaagggcaa tttcgtttgg ttgattacca tgcgttttca tcccctctgg
     3181 tttgtttaca ataatcaagt attgatcttg ataaacttcc tgcactaagt ctgggttgcc
     3241 ccaagggatc gtcttttggg gataatcttc ctcgtcaaaa gtcaactggc aaacatctcc
     3301 aggatttacg atttcgttcc agtggacttc ttcttgattt atcaaaatat gtttcttgat
     3361 tctcaaaaaa tgacggattt ttctagggat gaggagttgt tcctcaagta attgctttac
     3421 cgtcatttga ggtagagagg cgggtaatgt aaatgtgaat tgcatacaga tattgtaaca
     3481 aaaaaagccc tatttggata ggaaatagct aaattcttgt cttcctatga tgaagatgat
     3541 aaaataaacg catgaaatta gataaattat ttgagaaatt tctttctctt tttaaaaaag
     3601 aaacaagtga actagaggac tctgattcta ctatcttacg tcgctctcgt agtgatcgaa
     3661 aaaaattagc ccaagtaggt ccgattcgaa aattctggcg tcgttatcat ctaacaaaga
     3721 ttatccttat actaggtttg agtgcaggct tgctagttgg aatctatttg tttgctgtag
     3781 ccaagtcgac caatgtcaat gatttgcaaa atgccttgaa aactcggact cttatttttg
     3841 accgtgaaga aaaagaggct ggtgccttgt ctggtcaaaa gggaacctat gttgagctga
     3901 ctgatatcag taaaaacttg cagaatgctg ttattgcgac agaagaccgt tctttctata
     3961 aaaatgacgg gattaactat ggccgtttct tcttggctat tgtcactgct ggacgttcag
     4021 gtggtggctc taccattacc caacagctgg ctaaaaacgc ctatttatca caggatcaaa
     4081 ctgttgagag aaaagcgaaa gaatttttcc ttgccttaga attaagcaaa aaatatagta
     4141 aggagcaaat tctaaccatg taccttaaca acgcttattt tggaaatggt gtgtggggtg
     4201 tagaagatgc gagtaagaaa tactttggag tttctgcatc agaagtgagt ctggatcaag
     4261 ctgcgactct ggcagggatg ctcaaggggc cggaactgta taatcccttg aattccgtag
     4321 aagattctac taatcggcgc gatactgtct tgcagaatat ggttgcagca ggatatattg
     4381 ataaaaacca agaaaccgaa gctgctgaag ttgatatggc ttcgcaattg cacgataagt
     4441 atgaaggaaa aatctcagat taccgttacc cctcttattt tgatgcggtg gttaatgaag
     4501 ctgtttccaa gtataatcta acagaggaag agattgtcaa taatggctac cgcatttaca
     4561 cagagctgga ccaaaactac caagcaaata tgcagattgt ttatgaaaac acatcgctat
     4621 ttccgagggc agaggatgga acgtttgctc aatcaggaag tgtagctctc gaaccgaaaa
     4681 cagggggagt tcgtggagtt gtcggtcaag ttgctgacaa tgataaaact ggattccgga
     4741 atttcaacta tgcaacccaa tcaaagcgta gtcctggttc tacaattaag cctttagttg
     4801 tttatacgcc agcagttgaa gcaggctggg ctttgaataa gcagttggat aaccatacca
     4861 tgcagtatga cagctataag gttgataact atgcagggat caaaacgagt cgagaagttc
     4921 ctatgtatca agccttggca gaatcgctta atctacctgc tgttgccgct gttaatgatt
     4981 tgggtgtcga caaggctttt gaggcaggcg aaaaattcgg actcaacatg gaaaaggtcg
     5041 accgtgttct tggtgtcgcc ttgggaagcg gtgttgaaac caaccctctt caaatggctc
     5101 aagcatacgc tgcctttgca aatgaaggtt taatgcctga agctcatttt attagtagaa
     5161 ttgaaaatgc tagtggacaa gttattgcga gtcataaaaa ttcacaaaaa cgggtgattg
     5221 ataagtctgt agctgacaag atgaccagta tgatgttggg gactttcacc aacggtaccg
     5281 gtattagttc atcgcctgca gactatatta tggcagggaa aactggaaca actgaagcag
     5341 ttttcaatcc ggagtacaca agtgaccagt gggtaattgc ttatactccg gatgtagtga
     5401 ttagccactg gcttggcttt cctaccactg atgaaaatca ctatctagct ggctctactt
     5461 caaacggtgc agctcatgtc tttagaaaca ttgccaatac cattttacct tatacgccag
     5521 gaagtacctt tacggttgaa aatgcttata agcaaaatgg aattgcacca gccaatacaa
     5581 aaagacaagt acaaaccaat gataatagcc agacagatga taatttgtct gatattcgag
     5641 ggcgtgcgca aagtctagta gatgaggcta gccgggctat ctcagatgcg aagattaagg
     5701 aaaaggctca aacaatatgg gattcgatag tcaatctatt tcgctaagat gcttgtcaaa
     5761 gcctagcttt cttgttataa tggataggat ggaggcgtta tggcactaaa aaaagcaagc
     5821 ctagcttgtg cggtttgtgg ttcgagaaac tattcaatca agatcagcgg aaaccccaag
     5881 cctacacgac tagaagtaaa taaattttgt aagcattgtg gcaagtacac tacacacaga
     5941 gaaacgagat aggagagagc gatgcgtttt attggagata tttttagact tcttaaagac
     6001 acaacgtggc caactcgcaa ggaaagctgg agagattttc gttctatcat ggaatacaca
     6061 gctttctttg tagtaattat ttacattttt gaccagttga ttgtttcagg tttgattcga
     6121 tttattaaca ttttttagaa gattagtgga gttaattaca ctagaaatct tctatattat
     6181 gaaaggaaat atcatggata gttttgataa agggtggttt gttttacaaa cttattctgg
     6241 ttatgaaaat aaggtgaaag aaaatctatt acaacgtgca caaacctaca atatgttgga
     6301 taatattcta cgcgttgaaa ttccaacaca aacagtgcaa gttgaaaaaa atggaaagag
     6361 aaaagaagta gaagaaaatc gctttccagg ttatgttctt gtagaaatgg tcatgacaga
     6421 tgaagcttgg tttgttgttc gaaacacacc aaatgttaca ggatttgtcg gatcacacgg
     6481 gaacagatca aaaccaactc cattattgga acaagaaatt cgtgacattt tggtatctat
     6541 gggacaaact gttcaagaat ttgatttcga tgttgagatt ggtcaaactg tacgtattat
     6601 tgatggtgct tttgcagact acactggtaa gattacagaa attgataata acaaagtgaa
     6661 aatgattatc tctatgtttg gtaatgacac agttgcagaa gtaaacctaa accaaatcgc
     6721 agaattataa ccctgagaga ggctggagcc tctctttttt gtgcagttta ggagctaaag
     6781 ggaacagaat ggagaaaatg taacaaatgt gttttctaat ctgttagact gtatctagaa
     6841 aggggaaaat tatgattaaa gaattgtatg aagaagtcca agggactgt
//
LOCUS       DAVAZV010000082         6830 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVAZV010000082 DAVAZV010000000
VERSION     DAVAZV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.082"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(201..1625)
                     /locus_tag="VQT46_001998"
     CDS             complement(201..1625)
                     /locus_tag="VQT46_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET2371956.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEKIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMLKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQT46_001999"
     CDS             complement(2169..4448)
                     /gene="pulA"
                     /locus_tag="VQT46_001999"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET2371957.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQT46_002000"
     CDS             complement(4560..6518)
                     /gene="ligA"
                     /locus_tag="VQT46_002000"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET2371958.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQVRQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLSQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6611..>6830)
                     /locus_tag="VQT46_002001"
     CDS             complement(6611..>6830)
                     /locus_tag="VQT46_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET2371959.1"
                     /translation="FTQVQTKVESEFLGRVLSTIFTLAILFMPIAKGFMTVLPSVHLS
                     SFLIIGSGVIILSCISFIYVRTHFEKLI"
BASE COUNT         2020 a         1502 c         1238 g         2070 t
ORIGIN      
        1 actatatata gtaaaatgaa ataataacag gacaaatcga tcaggacagt caaatcgatt
       61 tctaacaatg ttttagaagt aaatctgtac tattctagtt tcaatatact ataataccaa
      121 aaagttcgta ttttttctat aattattatt attttatagc aaaaaataaa accaggaaaa
      181 caatttcctg attttacacg ttatttcaca tcaaaaacaa tggatttgac atttgtcatc
      241 gcttcaatgc tatatttaat tccttgcact ccagctccag aacctttgac accaaggaat
      301 gggaaattat ctggaccacg ctgggtttta ttattaatgt ggactgtacc tacttcaagt
      361 ttttcagcaa tttcaaaggc ttttttgaaa tcatttgtaa agactgatga ttgaaggccg
      421 aattcagatt cgttggcaaa ggcaatagct tcctctacac tagccacacg aatgattggt
      481 aaaacaggac caaatggctc ttcccatgcc actttcatat cttttgtaac ttggtcaaaa
      541 agcactggcc agaggagatt gccctcacgt ttgattggtg taagagcctg agcctctttt
      601 tcttgtgcat cctcaatcaa gccccaaatg aagtcggctg aagcattgtc aataacaggt
      661 gtaatatcag cattgtcaaa tggatcacca actgttaatt tagaaacttc ttcctgaagc
      721 aaagtagcta atttatctgc tacactttcg agaacaatga cacgtttaat ggccgtgcaa
      781 cgttgtcctg agtagctaaa ggctcccgca acaatttgct tggcagcatg ttccaaatct
      841 gcatcttcta gtacaagagc tgcatctttc ccaccaagtt ccaacatgat aggacgcata
      901 ccagctaaac gaccaatacg ttctccaata ggagttgaac ctgtaaagtt gatgaagttg
      961 acttctttgt gctcaatgat ataatcccca atttctgaac cacgacctgt aatggtgttg
     1021 aaaacacctg ccggaatccc tgcttcttca aatgctttag ccaacaagag tccagaaatg
     1081 gaaccttgtg ttggtggctt caacatgacc acattccctg caatcaaggc aggtgcaatt
     1141 ttagaagcag ataaattaac tggataatta aagggagcaa tcgctagcac gataccaact
     1201 ggttcacgac ggacaacagc cagtttgttt ttacttgctg cctcaaaacc accaccttcc
     1261 attgcttgtc cagtgatacg gagaccttcc tcagcagcat aacgaatcaa gtctgctgta
     1321 cgcactactt ctccaattgc tgctttaatc ccttttgcta cttctttggc aaggatagta
     1381 ccaatttttt ccttatcgcg ttctaaaata gctgctgttt tatgcaaata agccgcacgt
     1441 tcaattgctg ataaagctcg ccatgctggc agggctgcac gcgcagcttg catagcctca
     1501 tcagcttcag tctgagtcat ggctggaact gtacccaatt cttcttgatt gattggtgaa
     1561 taaatcgtaa tttcttgttc agatgatttc cattttccat ttactaaatt ctgatatctt
     1621 gtcaaattct tgtcctcctg aaaatgatta agatatattt taccaaattt tcagaaaata
     1681 acaacccttt ttgcaaaatt tttgagatta ttttcacaag cttgattttt caaagtatac
     1741 tcaataaaaa taaaaaaatc cactacgtca aggcgaggct aatgtggttt gaagaaattt
     1801 tcgaagagcg tgaatgagta tcatctatag taaaataaaa aaactgaaca atttggttgg
     1861 ggacagccaa accaatttct cacaatgttt cagaaacaag ggtgtgctat tccaatttca
     1921 gcctactata actgtcatag attgctgaaa caaagtctag gtaaaagtct tcataataaa
     1981 aagacctcct atcaaatgtt caaaaacttt gataggaggt cttgtttcgt gaaaatattt
     2041 atcaaatttt ctatacaagt gagctgttag ccaggttctt tctattcttt caatttcaat
     2101 gaatggattt tttaccaata ctcataactg ggaatttttc tgtctaaaaa tagcgagata
     2161 gatggtattt ataaaacact caagacagct agactaatat catttaaaac attatcttct
     2221 tttgagcgac tgttggttac caacatagct aaatttcctg cattttcaaa ttgatagggt
     2281 tctgatttag cattcacaac taccaagagg tgttctttgc cgtgaacttc atagataagg
     2341 cagccgctat gttcaatcgc agaatgcaca aagacatgat ggtaaatttc atcatagcta
     2401 gagtaagaaa aggcaccagt ttttgtcttc aatcggatga cttgacggat aaactcaata
     2461 ctgtcttgac gctcattaat caagttccag ttcacttggt tcacactgtc aggagcatta
     2521 tagctattca tcgcacgctc tctatcatca tgggtcaact caccattttc accagtcgca
     2581 accagtttgg tacgaccaaa ttcttgaccg atttccataa aggccatccc ctgcatgagc
     2641 agattcatgg ctgtggcagt ttcgaccttg cgcatgattt gctctgaact ttggtctgga
     2701 tgaagggttg ccaataaatc gtgaagattg taattgtcat gggcttctac atagttaagc
     2761 acctgatttg gatgtgtata gcttcctaat tcacgacttc ctaggattgc tttagctaga
     2821 attggctctg tcgcagcacc actgacaaaa cctgacttga tagcaccata aacttctccc
     2881 cctttgacag catcgcgctg attgtcatta aagaaaccaa tatttggcat ctggtaggca
     2941 ttgtccttct tggccttatc ataaggggca agacctgttc ccatatccca tccttctcca
     3001 tagaggataa tgttggagtc aatttcatcc aagctttgac gaatcatctg catggtcttg
     3061 acatcatgaa tccccatcaa gtcaaaacgg aagccgtcaa tattatattc ctgcacccag
     3121 tatagaagag aatcaatcat atacttgcga aacatttcgt gttcactggc tgtttcattt
     3181 ccaacacccg ttccattctg gaaggtacca tctggattca tacgataata gtaatcaggg
     3241 actgttgttt ggaatggtgc atcaacaact gagaaggtat ggttatagac tacatccata
     3301 atgactccaa tacccgcatc gtgataagct tgaaccatca ccttcaaatc acgaatgacc
     3361 tgagctggat catctggatt agttgaaaaa ctagtttctg gcgcgttata gttttgtgga
     3421 tcataacccc agttgtaggt tacatttcca tcctcatcgt attctttatg acggtctgca
     3481 attggttgca attgaacata attgtagccc agcttcttga tgtaatcaaa agcagttgac
     3541 tggccgtatt ggttaactgt tccagcctga gcagcaccca agaaagttcc tcgaagatgt
     3601 tcatctacac ccgatgtagg tgatttagtc aaatcacgaa tatgcatttc acagataact
     3661 gccttacatg gattttccaa gcgccaagta gcctccgaac cgtgcttaac ctcgaagttt
     3721 tcaacttgct tttctacatg gctcagaata gctgaacgtt tgccatcagg gctggtcgcg
     3781 attgtataag gatcacgtgt cagtgtttgg tgatgaggga attggacttg atactgataa
     3841 gtcttaccta ccaaatcttc ttcaacatcc aaactccaga caccgattgt attgtcctta
     3901 tgattataag agtagctatt gcctcttttc atctcaaaag tcttccaaac gggtgcatca
     3961 ttagcagctg attcataaac gacaacttgc acttctgtcg ctgtaggtga ccagagggaa
     4021 aaatgagcct gattgtcctc tacacggcaa cccaattctc cttggtaacc ccaatgatga
     4081 tcaaaactag cactgttaat ggccttatca aaggcaaaag gattttgatt tttatagaaa
     4141 ggactggcaa tagcaggatt ttcagagtaa taaatcctat catcgccttc caaaatccag
     4201 acctctgtta ataggggata gtgattaaaa cggatagaat attctttact agtttgacct
     4261 gtatgaacca caaaattcaa gctttctata acatgtgaac ttgggtgttc aaagctaaat
     4321 aaagctccaa aataatcttc tttgtaggtt agcaaatcaa ttcgttgatc ctgacttttt
     4381 acaaaggagc aagtgtcata ttctccattc ttacgatggt aatgaatgcg catagggtag
     4441 ttatacattt tttatttttc ctttttactt tgtttctatt tcactaataa atttttgtca
     4501 atctcgtctc aattaacaga catagtcata ttctctaaac tctgttttta aacgatccat
     4561 tacaaacttt ctagccatgc ctcatctctg acctggatac caagttcttg tgctttttgc
     4621 agtttacttc cagcgtctgc acctaccacg acgaggtcgg tctttttaga aacactacct
     4681 gtcactttgg cacccagact ttcgagttta cttttagctt ctgagcgctt gagtcgttcc
     4741 aattttcctg tcaataccac ggtcaaacct gacaaggccg catccgctac taccgtctgt
     4801 cctttatagt ccagattgac cccagtttct ttcaattctc tgagcagaat ttcagagcct
     4861 tctgtcgcaa aataagtctg aagacttttg gcaatcacgc cacctagact ttcaatacta
     4921 gccacttcct ctgaatctgc ctgagacaga ttttcaattg aatggaaata ttgaagtaaa
     4981 agctgactag ccttgcttcc gacatgacga attcccaaac caaataagag cttctcggca
     5041 gaattttcct ttgatgcttg gatagcctga tacagtttag cagcggactt ttccttaacc
     5101 ccctctaaaa ggaggaaatc ctcttcttgc aaacgataaa tatccgccac atccttgact
     5161 aaattagcag caaaaagctt ctcaacaata gatggaccaa ggcctgtaat attcatagca
     5221 tcacgagaag caaagtgaat caagccttcc atgatttgag cagggcaacg cggattgata
     5281 caacgtaggg ccacttcatc ttcaaagtgc aacaagtcag agttacaact tggacagttt
     5341 gtagggatat ctagtttttc ttcagaaacc cgtttggact ctaccacacg taaaacggca
     5401 gggatgatgt caccagcctt atatacaatg accgtatcgt cttttcggat atctttttca
     5461 gcaatataat ctacattgtg cagggtcgca cggctaacag tcgtaccggc aagttgtact
     5521 ggtgttagat tagcagttgg agttacaaca ccggtacggc caactgtcca gtcaactgat
     5581 aagagttgag cttctttttc ttcagcaggg aacttgtagg ctactgccca ctttggagcc
     5641 ttaacggtaa aaccaagttc ttcttgactt gctaggtcgt tgaccttgat taccactcca
     5701 tcaatatcgt aaggcagatt ttcccgttcc tgtcctactt cttggataaa attccagatt
     5761 tcatctatgt tttcagccaa gattcgctta ggattgacca caaaacctag ttgttctagg
     5821 tacttcaaac ccttttcttg gctatcacga gttgaagggc tggcttcttg atagagaaac
     5881 gttgcaagat tacgcttggc aactactgct gtatccaact gacgcagagt tcctgctgcc
     5941 gcattacgag gattagcaaa ttcaggctct ccattttctt ggcgcacttg gttaacttgg
     6001 tcaaaggaag cgcgtggcat gtaacattcc ccacgaactg tgatatctag ttcttctggc
     6061 aaagtcaaag ggatgtcctt aacacgcttg aggttttctg tgatattttc accaattgaa
     6121 ccatctccac gtgttacccc agcaaccaaa atcccctttt cataagtcag cgagatagat
     6181 aagccatcga ttttcagctc acaaatatag gtcggatgag ccacttcctt acgaacacgc
     6241 gcatcaaaag catctagctc ctcacgtgaa aaagcatcct gcaaactata aagaggatac
     6301 tgatgactgt atttttcaaa accatctaaa accttgccac caacacgatg agtcggactg
     6361 tctgctagca cttgctctgg ataagcagtt tctaactcga ccaactcacg gtaaaggcgg
     6421 tcatactcac tgtctgaaac cgagggatta tcgctggtat agtactcagt cgcatagcga
     6481 ttgagcaaag cgactaactc attcattctt ttattcataa gaccatttta ccataaaaca
     6541 agccctcctc acaaacgaga agggcggaaa aaacacttag tttgaaatta tttttgaaac
     6601 tcaagcaacc ttatatcaat ttttcaaaat gagttcgaac ataaataaac gatatacaag
     6661 acaagatgat aacaccactt ccaattatca ggaaagaaga gagatgtaca cttggcaaga
     6721 ctgtcataaa tccttttgca ataggcataa atagaatagc taaggtaaaa attgtactca
     6781 gtactcttcc aagaaattcg ctctcaacct tggtttgtac ttgagtaaaa
//
LOCUS       DAVAZV010000083         6739 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVAZV010000083 DAVAZV010000000
VERSION     DAVAZV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6739
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.083"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(84..1244)
                     /locus_tag="VQT46_002002"
     CDS             complement(84..1244)
                     /locus_tag="VQT46_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET2371960.1"
                     /translation="MKKKFALSFVALASVALLAACVEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTNMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(1345..1593)
                     /locus_tag="VQT46_002003"
     CDS             complement(1345..1593)
                     /locus_tag="VQT46_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET2371961.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQT46_002004"
     CDS             complement(1672..2262)
                     /gene="clpP"
                     /locus_tag="VQT46_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET2371962.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQT46_002005"
     CDS             complement(2436..3065)
                     /gene="upp"
                     /locus_tag="VQT46_002005"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET2371963.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETFQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(3154..3621)
                     /locus_tag="VQT46_002006"
     CDS             complement(3154..3621)
                     /locus_tag="VQT46_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET2371964.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(3640..4197)
                     /locus_tag="VQT46_002007"
     CDS             complement(3640..4197)
                     /locus_tag="VQT46_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET2371965.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            4322..5167
                     /locus_tag="VQT46_002008"
     CDS             4322..5167
                     /locus_tag="VQT46_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET2371966.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEDGGLLM
                     GYEID"
     gene            5226..6398
                     /locus_tag="VQT46_002009"
     CDS             5226..6398
                     /locus_tag="VQT46_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET2371967.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            6413..6658
                     /locus_tag="VQT46_002010"
     CDS             6413..6658
                     /locus_tag="VQT46_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HET2371968.1"
                     /translation="MEQSPKKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(6655..>6739)
                     /locus_tag="VQT46_002011"
     CDS             complement(6655..>6739)
                     /locus_tag="VQT46_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET2371969.1"
                     /translation="TTYRNHRKRFGLRMNLSAGIINHELGF"
BASE COUNT         1925 a         1405 c         1304 g         2105 t
ORIGIN      
        1 agtttgaaga gattttcgaa gagtattaaa tatcgaaaca gggagtgagt caaaggctca
       61 ttccctattt caacattttt ctattatggt tttacaactt ctgctgcttc aactttacca
      121 ttgttcatgg tcatcatgta agcagttttg actgtgttgt ggtctgcatc gaagcttgtt
      181 tgaccagtta caccttcaaa atcttttgtt ttagcaaggt tatccttgat ttcacctgaa
      241 tttttagcac cttttgctgc gtttgctaca aggtgaactg aatcataagc caaggctgca
      301 aatgttgaag gctcttcatt gtacttagca cggtaagcgt caaggaaggc tttagcttta
      361 gctgaaactt ctacagtagt tgagaagcct gagataaagt agatgtttga tgctttttca
      421 gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat caccaccaac gattggtttg
      481 tcaattccca tgccacgcgc ttggtttaca atcttaccag cctcattata gtaaccagga
      541 acaacgatag catcaaagtc tttccctttc atgtttgtaa gggctgcttg gaagtctgtg
      601 tcacctgcta cgaaagtttc atctgcaacg atttcaccct tgtatgactc gcggaaagat
      661 ttagcaatcc ctttagcata gtcactggca ttgtcagtgt aaagaacaac tttcttagca
      721 tttaattttt cagaaacata gtttgagata atttttcctt ggaagctatc ttggaaagtt
      781 ccaataaaga ggtaatcttg acctttagtc aatccatctt gagtcgcact tggtgagatc
      841 aatggaacac ctgcttttgt agcgttcgct accgcagctg cagtcgcacc agatgtcgca
      901 ggtcctacga ctgctgatac tttagattgg gttacaaggt tagttgtaac tgaagcagcc
      961 tcagctgttt cagacttatt atctttatcg actacttcga tttgttttcc atcgatacca
     1021 cctgcggcat tgatttcatc aacagccaat tgggcacctt tttgttcagc tgttccgtat
     1081 gcagctaaag aacctgattc ttcaaagtta aacccgattt taattgtctt ttcctctact
     1141 gagttaccag cagtgttgac tgctccagac ttcacttcta cacaggctgc aagaagtgct
     1201 acacttgcaa gcgccacaaa cgatagggca aattttttct tcatcttttt gtctccttat
     1261 ttcttaaata gtctgttaag aatataccga attatcagaa aattgtcaat gttttccttg
     1321 aactttttcg atgataacgt tttcctatcg ataaagattg cccacaaagg gtgtttccaa
     1381 ctcttggata tgacaaaccc taactttttt aataaatttt tccttgctca agcgtccgac
     1441 caattgctcc acttcttgag ttggaacata gagttgtaag taacgatgtt tcttggaatg
     1501 ataggtaata tctccataat cctgcagttt tttggcatca cgattatagt aaagatagat
     1561 aatcaagcca gagcgattga ctttttcaaa catgataaat cctctttcta agaaatctct
     1621 ccctattata ccaaaaaaag caaacccagt cgagtttgcc ttctatcatc attagttcaa
     1681 tgaattgttg gccataattt catcaataaa gccatattca agtgtttcct gggcgctcat
     1741 ccagttatca cgttctgcat ctgcatggac tttttccatt gactgacctg aattttcagc
     1801 caagattttt tccaaggtat tacgagtttt gagcaagtgt tctgcagcga tagccatatc
     1861 agtttgttgg gtaccaccac ctgtaccgcc cattggttgg tgaatcatgt attcagcatt
     1921 tggaagcatg aaacgtttgc cttttgctcc acttgatgcg atgactgttc ccatagatgc
     1981 agccattccc ataacaatgg tttggacatc tgccttgata aagttcatgg tatctacgat
     2041 tgccaaacca gctgaaacag aaccacctgg tgtattgaca taaaggtaaa tatcttttgt
     2101 actatcttgg gcatccaaga aaagcagttg ggcaataaca gagttagcca tattgtcttc
     2161 aaccggacct gtcagcataa tgatgcggtc tttgagaaga cgtgagtaaa tatcgtaaga
     2221 acgttctcca cggcttgttt gttcaataac tacaggaatc attcatttct ccttttgagt
     2281 tttaattttg ttggtcaaat gactgaagat aagactatta taatatcttg gtcaaaaaag
     2341 gtcaaatttt tgctctgctt tcattagaca gaaacaaaaa cccaacctcc tttcgtgact
     2401 ggaaatactt ttccaagtca ttcttctttt cgatcttatt ttgtaccgaa caagcggtct
     2461 ccagcatctc caagacctgg aacgatataa ccgtgttcgt tcaaacgttc atccaaggct
     2521 gctgtaaaga tttctacatc tggatgagct tcttgaaggg cttttacacc ctctggagca
     2581 gatacaaggc agacaaattt gatatttgat gcgccacgtt ttttaagaga atcaacagcc
     2641 aagattgctg agccacctgt tgccaacatt gggtctacta caaaaatttg acgttggtca
     2701 atgtcctcag gcaatttcac caagtattca actggttgaa atgtttcttc atcacggtac
     2761 ataccgatgt ggccaacttt agcagctgga accaagctca agagaccatc aaccatcccg
     2821 atacctgcac gcaagattgg gacgatggcc aatttcttac ctgccaattg tttttgaact
     2881 gtttttgtaa ttggtgtttc gatttccaca tcttctagtg gaagatcacg aagtacttca
     2941 taccccatca acattgcaat ctcatctact agctcacgaa aagcttttgt agaagtatct
     3001 gtacgacgca agattgacaa tttgtgttga atcagtgggt gattaataac ttcaattttt
     3061 cccatttttg gaattccttc tttcaattta ttcttcttat tataccaaaa aacgggttaa
     3121 aaatctttct aaaccattta tttttgataa tttttacatt agatcagcct ctttaagagc
     3181 tgtctgtact gtctcaagtg gtaaatgggt caattctgtc cctttttctt gataaaggta
     3241 ttgggcgtag tcgtccattc ggtactggtt gatataaacc acacgcttgc agccgacctg
     3301 aagcaattgt tttgtacagt tgagacaagg aaaatgggtt acataggctg taaagccttt
     3361 gggaacacca cgctcagcac cttgaaggat agcattgacc tcagcgtgaa gggtgcgaac
     3421 acagtggcct tcaatgacca aacattcgtg atcaatacaa tgctcagtcc ctgacaccga
     3481 accattgtaa ccagtggaaa taaccttatt atcttttacc agaatcgcgc ccactttagc
     3541 acgtttacaa gtggaacgat tcgcaattag tagagcttgg gctgcaaaat actcatccca
     3601 ggccagtctt ttttcagtca tctcttttct cctttttctc tattttttaa aaaatggtaa
     3661 acctaaatct gcaatctttt cagctggtac cttcatgcca tccttgatcc attttagaag
     3721 gacagagacg atggctgagc tccagaagga atgaagataa gagctgacac cttttgattt
     3781 cccatggtat ttttctagaa attcctgcat ggcttggaca aagatttttt ccagatggta
     3841 atccaaggcc aattgaatta ctctagcttc ctttctggcc tcccggaaaa ggtgaaccca
     3901 aaccaaataa aggtctgtct ttaaatcgta atgatgcagc tgttccataa tattgtggac
     3961 agttcgttta aagacgctct ctaaaatttc ctctttggag tcataattgc gataaaaggc
     4021 cgcacgcgaa acacctgcac gtttgaccaa ttcagaaata ctaatcttgg tcagttcctt
     4081 tttttccaag agttgcaaga gggctgtttc aatggcttct ctggttaata aattggattc
     4141 ttggtttgat tttctgagat tttcaagaga cttttcagag attctacgtt cagacataac
     4201 attttctttc tacttgtcac aacagacgga tgatgctttt gtttcaaggg ttttcatgat
     4261 ataattgtaa aaaaagacag aacctttgtc aatgtataac tgacaaagat ggagaatttc
     4321 tatgacttgg aagattattg ctgactctgg ttgtgattat cgtcaactgc caacaccagc
     4381 tattaacaca acctttgtaa gtgtcccctt aaccattcaa gtagctgatc aggtctttgt
     4441 tgatgacgcc agtctcgata ttgaccaaat gatggaaacc atgtatgcaa ctgcagaagc
     4501 ttcaaaatcg gcttgtccaa gcccagatga ctatttgcga gcatttgaag gtgccaaaaa
     4561 cattttccta gtaaccatca caggtaccct ttctggcagt cacaatagtg ctcaactagc
     4621 aaagaatatt tatctggaag accatcctga cactaagatt catgtgattg atagtttatc
     4681 tgctggtggt gaagttgacc tactcgtaga aaaattgaat gacttgattg accagggctt
     4741 gtcttttgaa gaagtggttg aagctatcac cgcctatcaa gaaaaaacta agttgctctt
     4801 tgtcctagcc aaagtcgata acttggtgaa gaacggccgt ttgagcaagc ttatcggtac
     4861 ggtcgttggc cttctcaaca ttcgtatggt cggaaaagct agtgaaactg gaactctcga
     4921 attgctacaa aaagcaaggg gatcaaagaa atcagttcaa gctgcctatg atgagttagt
     4981 aaaagctgga tatgctggtg gccgtattgt catggcccaa cgcaataacg aaaaatgttg
     5041 tcaacagctc tcagagcgaa tccgtgaaac cttcccacaa gcggatatta aaattctacc
     5101 aacctctggt ctctgcagtt tctatgcaga agatggcggt ttgctgatgg gctatgaaat
     5161 tgattaattg tattcttgac aagaggtgac catcatctct tgtttttttg tggtacaata
     5221 gagctatgaa acattttgat actattgtca tcggtggggg acctgctggt atgatggcta
     5281 cgatttccag tagcttttat ggacagaaaa ccctcctcat cgaaaaaaat cggaaacttg
     5341 gaaaaaaatt agctgggact ggtgggggac gttgcaatgt gaccaacaat ggtagcttag
     5401 acaacctgct agctggaatt cctggaaacg gacgctttct ttacagtgtt ttctcccagt
     5461 tcgataatca tgacatcatc aactttttta cagaaaatgg tgttaaactt aaggtcgaag
     5521 accacggacg cgtctttcca gccagtgaca agtctcggac tattatcgaa gctttggaaa
     5581 agaaaatcac cgaactaggt ggtcaagttg ctactcaaat agaaatcgtt tctgttaaaa
     5641 aagtagatga ccagtttgtc cttaagtcag cggatcaaac cttcacttgt gagaaactca
     5701 ttgtcacaac aggtggtaag tcttatcctt cgactggttc gactggtttt ggtcacgaga
     5761 ttgctcgcca ttttaagcat accatcaccg atcttgaggc tgctgaaagt cctttattaa
     5821 cagattttcc acataaagcc ttacaaggga tttctttgga cgatgtgacc ctaagttatg
     5881 gtaagcatgt catcactcat gatttactct ttacccactt tggtttgtca ggtcctgctg
     5941 ccctacgcat gtctagcttt gtcaaaggtg gggaggttct ctcactcgat gttttgcctc
     6001 aactttctga gaaggacttg gttacatttc tagaagaaaa tcgggaaaaa tccttgaaaa
     6061 acgctttaaa aaccttgtta ccagaacgct tggccgaatt ttttgtacaa ggatatcctg
     6121 aaaaagtcaa acaactgact gaaaaggaac gagaacaact tgtccagtcc attaaagaac
     6181 ttaaaattcc tgtaactgga aaaatgtccc ttgcaaagtc ctttgttacc aagggtggag
     6241 tcagtctcaa ggaaatcaat cctaaaaccc ttgaaagtaa gctggtacct ggcctccact
     6301 ttgcaggcga agttatggat atcaatgccc acacaggtgg ctttaacatc acttctgccc
     6361 tctgtaccgg ctgggtggcg ggatcaaatc caatctaaat atacattact aaatggaaca
     6421 atcccccaaa aaaaagaaag gaactacttt ggaacatatt atcttgctaa ggggagtcac
     6481 tcctaatgga aaaaatgcta tccctaaaat gtcttatcta gtagatatct tgacagaagc
     6541 tgattttcaa caagttcgaa cttatattca aagtggaaat attattcttg aaagtaactt
     6601 agctctcgaa gaaatacgag aacaggttca tactctatta gacttcctgc aaaactagaa
     6661 tcctagttca tgattgataa taccagcact caaattcatt cgtaatccga agcgtttacg
     6721 atgatttcga taggttgtt
//
LOCUS       DAVAZV010000084         6447 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVAZV010000084 DAVAZV010000000
VERSION     DAVAZV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6447
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.084"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            222..422
                     /locus_tag="VQT46_002012"
     CDS             222..422
                     /locus_tag="VQT46_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371970.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            447..863
                     /locus_tag="VQT46_002013"
     CDS             447..863
                     /locus_tag="VQT46_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371971.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQT46_002014"
     CDS             1094..1801
                     /gene="ccdA2"
                     /locus_tag="VQT46_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET2371972.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYVMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1812..2369
                     /gene="sdbB"
                     /locus_tag="VQT46_002015"
     CDS             1812..2369
                     /gene="sdbB"
                     /locus_tag="VQT46_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET2371973.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            2490..3881
                     /locus_tag="VQT46_002016"
     CDS             2490..3881
                     /locus_tag="VQT46_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET2371974.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPSWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4024..4941
                     /gene="adcAII"
                     /locus_tag="VQT46_002017"
     CDS             4024..4941
                     /gene="adcAII"
                     /locus_tag="VQT46_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET2371975.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLESDPQNDKTYLENLEENMSILAEELK"
     gene            4949..>6447
                     /locus_tag="VQT46_002018"
     CDS             4949..>6447
                     /locus_tag="VQT46_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2371976.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVDGKYYVYLKDAAHADNIRTKEEIKRQKQER
                     SHNHNSRADNAVAAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDL
                     SASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSL
                     LRELYAKPLSERHVESDGLVFDPAQITYRTVNGVAVPHGDHYHFIPYSQLSPLEEKLA
                     RMIAVKGQNGAVLPGMHYLKPAPKPQVQPSTEKKQTDFAVEQVVRKVGEGYVVEIAGV
                     SHYVFAKDLAKDKIDAIENLLSKKTQETHALVAKKENVAPRDQEFYDKAYNLLTQAHK
                     VLSENKGRTSDFQALDKLAERLNNESSNKVKLVDDLLAFLAPITHPERLG"
BASE COUNT         1980 a         1172 c         1354 g         1941 t
ORIGIN      
        1 atggtttcag aaatttctct taccaacatt aaccacacca tcggttatta tagtaaaatg
       61 gaataagaac aggacaaatc gatcaggaca gtaaaatcga attctaacaa tgttttagaa
      121 gtctatatgt actattctag tttcaatata ccataactgc tcctagtcaa cctgcaagtc
      181 ctgtcccagc tccaagctca gctccgactc aagatcctag agtggtagca agcgcttcgg
      241 ctagctcaac gagcacacaa gctcaagagc aagttgacaa gtctgaactt cgtgccttga
      301 gtcaagagtt agaccaacgc ttgaaagctt tggcaacagt atctgatcca aaaatcgatg
      361 caaccaaggc tgtcctccta gatgctcaaa aagctccgga agatagtgcc ttgacagagt
      421 aaggtctgca tactgcagta gagtctgtga aggctgcctt ggactctctc aaagatgtga
      481 aagcaaatgc tagcgacagc aagcctgcac aggacaagaa ggatgcaaaa caaggaacgg
      541 aagatagtaa ggattcagat aagatgactg aaacaaactc agttccggca ggagtgattg
      601 tggtcagtct acttgccctc ctaggcgtga ttgccttctg gctgattcgc cgtaagaaag
      661 agtcagaaat ccagcaatta agcacggaat tgatcaaggt tctaggacag ctagatgcag
      721 aaaaagcgga taaaaaagtc cttgccaaag cccaaaacct tctccaagaa acccttgatt
      781 tcgtgaaaga agaaaatggc tcagcagaga cagaaactaa actagtagag gagcttaaag
      841 caatccttga caaactcaag taaaacatga tttatgaaat gtcagaccta aaagacattt
      901 tcgttcacaa aagcagtgac gagtaatcct tgtcgttgct ttttggctat tttgggggat
      961 aagatccgcc ttgactagca aaagaaaaga ttggtccaat agtgcccgat acgattttgc
     1021 gtagcagaaa gcttacaaat aaaattgaat atagtaaaat aggattagaa ttattaagaa
     1081 agttggttct ttattggaaa cgatagtatt tttaatctct gtttttctag caggtgtttt
     1141 atcctttttt tctccttgta tttttcctct tctgccagtc tatgctggga ttttattgga
     1201 tgatcaagaa agtgcaaaaa gcttttcttt gtttgggaga aaggttctct ggtcaggctt
     1261 gattcgaaca ctttgcttta tcgctggtat ctctctcatt ttctttattc taggctttgg
     1321 tgctggttac tttggtcata ttctctatgc aaattggttt cgatatgtca tgggagctat
     1381 tattatcatt ttgggtcttc accagatgga aatttttcat ttgaagaaat tagaagttca
     1441 aaaaagtttt acctttaaaa aatcagattc taatcgttat tggtcagctt ttttacttgg
     1501 tattaccttt agctttggtt ggacaccttg tattggtcca gttttaagtt ctgttttagc
     1561 acttgcggct tctggaggca atggtgcttg gcaaggagcg atttatactc tcatttacac
     1621 tctgggcatg gcccttcctt tcttggtctt ggcactagct tcaggtctag tcatgccata
     1681 ttttagtaaa atcaagcgtc atatgatgct actaaagaaa attggtggtt tcctcattgt
     1741 tttaatggga attttgttac tattaggaca agtaaatgtt ctagctggaa tttttgaata
     1801 aaggaggaca aatgaaaaaa gtaatgtttg ctggcttaag tctcttgtca ttagttgtat
     1861 tgatggcctg tggtgaggaa gaaactaaaa agactcaagc agcacaacag ccaaaacaac
     1921 aaacgactgt acaacaaatt gctgttggaa aagatgctcc agacttcaca ttgcaatcca
     1981 tggatggcaa agaagttaag ttatctgatt ttaagggtaa aaaggtttac ttgaagtttt
     2041 gggcttcatg gtgtggtcca tgcaagaaaa gtatgccaga gttgatggaa ctagcggcga
     2101 aaccagatcg tgatttcgaa attcttactg tcattgcacc aggaattcaa ggtgaaaaaa
     2161 ctgttgagca attcccacaa tggttccagg aacaaggata taaggatatc ccagttcttt
     2221 atgataccaa agcaaccacc ttccaagctt atcaaattcg aagcattcct acagaatatt
     2281 taattgatag ccaaggaaag attggaaaga ttcaatttgg tgctatcagt aatgcggatg
     2341 cagaagcagc atttaaagaa atgaactaga atcgataaaa tctgattaca agatgtagtc
     2401 agattttttt agaaaaacat tttataaata ttcacatatc tcctatattt atggtaaaat
     2461 agaattatca gtttattttg gagtcaaaga tgaatatatt tagaacaaag aatgttagtt
     2521 tagataaaac agagatgcat aggcatttga agttatggga tttgattttg ctgggtatcg
     2581 gagccatggt agggacaggc gtctttacaa tcacaggtac tgcagctgca acacttgctg
     2641 gcccagccct agtgatttca atcgttattt ctgccttgtg tgtgggatta tcagccctct
     2701 tttttgcaga atttgcctcg cgagtacccg ctacaggagg tgcctatagt tacctctatg
     2761 ctatcttagg agaattccct tcctggttgg ctggttggtt aaccatgatg gagttcatga
     2821 cagccatatc aggcgtagct tcgggttggg cagcttattt taaaggcttg ctctctcaat
     2881 acgggatagc ctttcctcag gctttaaatg gtacctttaa tcctcaagca gggacatttg
     2941 ttgatttatt gcctattctt gtcttggtct tggtgacttc gcttgtttta ctaaatgcca
     3001 aggcagcctt acgctttaat tcgattctag ttattttgaa attttccgct ttagctctct
     3061 ttgttttagt aggaatttgg aatattaagt ttgataattg gagcaatttt gctccttacg
     3121 gttttggaca aatctatgga gctagcactg gtattatggc tggtgcgtcc ttgatgttct
     3181 tcggtttttt gggatttgaa tccatctcta tggctgtaga tgaagtcaag actcctcaaa
     3241 aaaatattcc tagagggatt gtcttatcgc tttctatcgt aaccattctc tatgccttgg
     3301 tgacccttgt tttgactggt gtggttcact atagtcattt aaatgtcgat gatgccgttg
     3361 cctttgccct tcgtagtgtt gggattagtt gggcagccaa ctatgtgtca ttagtggcta
     3421 tcttgacctt gattacagtt tgtatttcga tgacctatgc cctatcgcgt atgatttaca
     3481 gtttagcacg tgacggctta gtgcctgctg cctttaagga actgacgaag actagcaaga
     3541 taccaaagaa tgctactatc ttgacaggtc tagcttcagc agtagcagca ggaatgttcc
     3601 cactagccag tattgcagcc tttttaaata tttgtacctt agcctacttg atcatgctgg
     3661 cttatggtct gattcgctta cggaaagaaa aaggaatgcc caaagctggg gaatttaaaa
     3721 caccattggt acctctgtta ccaattttat cgatcatcat ttgtttatcc ttcatgttac
     3781 agtataatat gaacacctgg attgctttcc tagttgcgtt gttagtagga agtattattt
     3841 acttcactta tggctataag cattctacca tagaagaata aagtgaaagt ctattgagtt
     3901 gttgacactc agtagatttt tatatgtgaa agaaatttca aattttttct aaaaatatct
     3961 tgacagatta aattttcagg agtagaatat ttactagtta attaaatggt taaggagttg
     4021 ttcatgaaga aacaaaattt atttttagtc ctgttaagtg tctttctttt gtgtttgggg
     4081 gcttgtggtc aaaaggaaag tcagacagga aaggggatga aaattgtgac cagtttttat
     4141 cctatctacg ctatggttaa ggaagtatct ggtgacttga atgatgttcg gatgattcag
     4201 tcaagtagtg ggattcactc ctttgaacct tcggcaaatg atatcgcagc catctatgat
     4261 gcagatgtct ttgtttacca ttctcataca ctcgaatctt gggcaggaag tctggatcca
     4321 aatctaaaaa aatccaaagt gaaggtctta gaggcttctg agggaatgac cttggaacgt
     4381 gtccctggac tagaggatgt ggaagcaggg gatggagttg atgaaaaaac gctctatgac
     4441 cctcacacat ggctagatcc tgaaaaagct ggagaagaag cccaaattat cgctgataaa
     4501 ctttcagagg tggatagtga gcataaagag acttatcaaa aaaatgcgca agcctttatc
     4561 aaaaaagctc aggaattgac taagaaattc caaccaaaat ttgaaaaagc gactcagaaa
     4621 acatttgtaa cacaacatac agccttttct tatctagcga agagatttgg gcttaatcaa
     4681 cttggtattg caggtatctc tcctgaacaa gaaccaagtc cacgacaact aacagaaatt
     4741 caggaatttg ttaagaccta taaggttaaa acgattttta cagaaagtaa cgcttcttca
     4801 aaagtagctg aaactcttgt caaatcaaca ggtgtgggtc ttaaaactct gaatccttta
     4861 gagtcagacc cacaaaatga caagacctat ttagaaaatc ttgaagaaaa tatgagtatt
     4921 ctagcagaag aattaaagtg aggaaagaat gaaaatcaat aaaaaatatc tagcaggttc
     4981 agtggcagtc cttgccctaa gtgtttgttc ctatgaactt ggtcgtcacc aagctggtca
     5041 ggttaagaaa gagtctaatc gagtttctta tatagatggt gatcaggctg gtcaaaaggc
     5101 agaaaatttg acaccagatg aagtcagtaa gagagagggg atcaacgccg aacaaattgt
     5161 tatcaagatt acggatcaag gttatgtgac ctctcatgga gaccattatc attactataa
     5221 tggcaaggtt ccttatgatg ccatcatcag tgaagaactt ctcatgaaag atccgaatta
     5281 tcagttgaag gattcagaca ttgtcaatga aatcaagggt ggctatgtga ttaaggtaga
     5341 cggaaaatac tatgtttacc ttaaagatgc agcccatgcg gacaatattc ggacaaaaga
     5401 agagattaaa cgtcagaagc aggaacgcag tcataatcac aactcaagag cagataatgc
     5461 tgttgctgca gccagagccc aaggacgtta tacaacggat gatgggtata tcttcaatgc
     5521 atctgatatc attgaggaca cgggtgatgc ttatattgtc cctcacggca atcacttcca
     5581 ctatattcct aagagtgatt tgtctgccag tgaattagct gctgcccaag cctattggaa
     5641 tgggaagcag ggatctcgtc cttcttcaag ttctagtcat aatgcaaatc cagctcaacc
     5701 aagattgtca gagaaccaca atctgactgt cactccaact tatcatcaaa atcaagggga
     5761 aaacatttca agccttttac gtgaattgta tgctaaaccc ttatcagaac gccatgtaga
     5821 atctgatggc ctagtatttg atccggcaca aataacatat cgtacagtca atggtgttgc
     5881 tgtaccgcac ggagaccatt atcactttat tccttattca caactgtcac ctttggaaga
     5941 aaaattggct cgtatgattg ctgttaaggg acaaaatggt gcagtcttgc caggaatgca
     6001 ttatttgaaa ccagcaccaa aaccgcaagt tcaaccatca actgagaaaa aacaaactga
     6061 ttttgcagta gaacaggttg ttagaaaagt tggagaaggc tatgttgtgg aaattgctgg
     6121 tgtcagtcac tatgtttttg ctaaagactt ggctaaggat aagattgatg ctattgaaaa
     6181 tctcttgtct aagaaaactc aagagacaca tgctctagtt gctaaaaaag aaaatgtcgc
     6241 tcctcgtgac caagaatttt atgataaagc ttacaatctg ttaacccagg ctcataaagt
     6301 cttgtctgaa aataaaggtc gtacttctga tttccaagcc ttagacaaat tagcagaacg
     6361 cttgaataat gaatcttcta ataaagtaaa attggtagat gatttattgg cattcctagc
     6421 accaattacc cacccagaac gccttgg
//
LOCUS       DAVAZV010000085         5064 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVAZV010000085 DAVAZV010000000
VERSION     DAVAZV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5064
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.085"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(149..226)
                     /locus_tag="VQT46_002019"
                     /pseudo
     CDS             complement(149..226)
                     /locus_tag="VQT46_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            384..602
                     /locus_tag="VQT46_002020"
     CDS             384..602
                     /locus_tag="VQT46_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HET2371977.1"
                     /translation="MKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVS
                     AIDSSEAMLLPTINVLELLDKSQPFEEE"
     gene            1647..2639
                     /locus_tag="VQT46_002021"
     CDS             1647..2639
                     /locus_tag="VQT46_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET2371978.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYDGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            2641..3459
                     /locus_tag="VQT46_002022"
     CDS             2641..3459
                     /locus_tag="VQT46_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET2371979.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVIYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            3461..4246
                     /locus_tag="VQT46_002023"
     CDS             3461..4246
                     /locus_tag="VQT46_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET2371980.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            4285..4563
                     /locus_tag="VQT46_002024"
     CDS             4285..4563
                     /locus_tag="VQT46_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET2371981.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTRFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            4548..4745
                     /locus_tag="VQT46_002025"
     CDS             4548..4745
                     /locus_tag="VQT46_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2371982.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1450 a          843 c         1061 g         1710 t
ORIGIN      
        1 gtgtgagagg ggctagagat tatcccctac tcgatttcga aatctagtgg aatgaatctg
       61 gaatagtcca tcgagctttc taatactctt cgaaaatctc ttcaaaccac gtcaacgtcg
      121 ccttgccgtg cgtatggtta ctgacttcgt cagttctatc cacaacctca aaacagtgtt
      181 ttgagcaacc tgaggctagt ttcctagttt gctctttggt tttcatttag tataacagat
      241 tgttagaagt tggtttaaat ttcctaatca gtttgttcac atttaccttc gatatattat
      301 atcccatagt taaggttggt catacagatg attatagtca tggagccgta aaacttagtg
      361 tttctttagt tgacaaagat gccatgaaaa aaatatctgt aactgtaata ggatattttg
      421 aaataaatat agatgaaaat atcaccgata ttctatacgt aaatggtact gctattcttt
      481 atcattattt acgttctatt gtttcaatag tttcggcaat tgatagcagt gaagcaatgt
      541 tgctacctac cattaatgtt ttagagttac tagataaatc tcaacctttt gaagaagaat
      601 aatttattag ctcactaaat tgagggtaag gaaaagtaaa atcagtaaga aaaatgtctt
      661 gcattataca gcaacctttt gggaatgagt agatggattg aataaaattt tattaagagt
      721 ggatgattta tctgtagatt attattggac agttagtctt gaagtagtct aagaattagg
      781 ttataatcag tagaatcctt gctaataatg aggaggttag tttatgtata gtagactgaa
      841 tctaaaatag tacgaaacaa ttgctaaaac atttatagaa attaatttta ctttcccaat
      901 cgatttgttc tcatcttatt tcaatccgct atatattatg gtatcgaatc ttcatcagaa
      961 tgataaaatt aatcaattga tatctgatta caaacagaat atgaaagctt tttatatcac
     1021 tattgaaaaa tttatacgag atgatgaaag ccttaagtgt tattttataa aggttatttc
     1081 aagtcgttcc aaggtaacaa gtctagatca gattgaagct gataaaacga tacaaagaaa
     1141 atattcaagt gagctaaaaa aatttattgg attttataat gagattattt gtgaggaaaa
     1201 tagtttccta catgtacgaa agaggtggtc gagttggttt aggtagtcga tgcgtgagtt
     1261 gataattctc agggtatgga cttctttttc atgaatgagg taaaagagca ggtattgttt
     1321 agagacaatc attctgagca tattttctgg atagagggag tatccgattt tatgatcaaa
     1381 gttaataccg ccctctggtg agaagatgag taggttggta atttaaacta ttaaacagaa
     1441 tttttgatta aaagtattat tttatgagag aaatcctaat ttcacaatcc ataggcaaac
     1501 tcttgcattt cgttttttat tggactataa taggttggta taaagccttt tgtagtaata
     1561 aaatgtagaa ggtgtagaaa gcaaggattt agaatatttg tagttaaaaa cacaatgttg
     1621 ctattcctta cgatagggag atagatatgg caatgataga agtggaacat cttcagaaaa
     1681 attttgtgaa gactgttaag gaaccgggct tgaagggggc tttgcgctcc tttattcatc
     1741 ctgaaaagca gacctttgaa gcggtcaagg atttgacctt tgaggttcca aaagggcaga
     1801 ttttaggatt tatcggggca aatggtgctg ggaagtcgac aaccattaaa atgctgacag
     1861 gaattttgaa accaacatct ggtttttgtc ggattaacgg caagattccc caggacaatc
     1921 ggcaagatta tgtcaaagat attggcgtag tctttggaca acgcacccag ctatggtggg
     1981 atttggctct gcaagagacc tacactgtct taaaagagat ttatgatgtg ccagactcgc
     2041 tctttcataa gcgtatggac tttttgaatg aagtcttgga tttgaaggac tttatcaagg
     2101 atcccgtgcg gactctttca ctgggacaac ggatgcgggc ggatattgcg gcctccttgc
     2161 tccacaatcc caaggttctt tttttagatg agccgaccat tggtttggac gtttcggtta
     2221 aggataatat tcgtcgggca attactcaga tcaatcaaga ggaagaaact accattcttt
     2281 tgaccactca cgatttgagt gatattgagc aactttgtga tcggattttc atgattgaca
     2341 aggggcaaga gatttttgat ggaacggtga gccaactcaa ggagaccttt ggtaagatga
     2401 agactctctc ttttgaactg ctaccaggtc aaagtcatct cgtctctcac tatgacggtc
     2461 tgtctgatat gaccattgat agacaaggaa acagcctcaa cattgaattt gatagttctc
     2521 gctaccagtc agctgacatt atcaagcaaa ccctgtctga ttttgaaatc cgcgatttga
     2581 agatggtgga tacggatatt gaggatatta tccgtcgctt ctaccgaaag gagctctagg
     2641 atgatcaaat tgtggagacg ttataaaccc tttatcaatg caggggttca ggagttgatt
     2701 acttaccgag tcaactttat tctctatcgg attggcgatg tcatgggggc ttttgtggcc
     2761 ttttatctct ggaaggctgt ctttgattct tcgcaagagt ctttgattca gggcttcagt
     2821 atggcggata tcaccctcta catcatcatg agttttgtga ccaatcttct gactagatcc
     2881 gattcgtcct ttatgattgg ggaggaggtc aaggatggct ccattatcat gcgtttgttg
     2941 cgaccagtgc attttgcggc ctcctatctt ttcaccgagc ttggttccaa gtggttgatt
     3001 tttatcagcg ttggccttcc atttttaagt gtcattgtct tgatgaaaat catatcgggt
     3061 caaggtattg tagaggtgct aggattaact gtcatttatc tttttagctt aacgctcgcc
     3121 tatctgatta actttttctt taatatttgc tttggatttt cagcctttgt gtttaaaaat
     3181 ctttggggtt ccaacctact taagacttcc atagtggctt ttatgtcggg gagtttgatt
     3241 cccttggcat tctttccaaa ggttgtttca gatattctct cctttttgcc tttttcatcc
     3301 ttgatttata ctccagttat gatcattgtt ggaaaatacg atgccagtca gattcttcag
     3361 gcactccttt tgcagttctt ctggctctta gtgatggtgg gattgtctca gttgatttgg
     3421 aaacgggtcc agtcctttat caccattcaa ggaggttagt atgaaaaaat atcaacgaat
     3481 gcatctgatt tttatcagac aatacatcaa acaaatcatg gaatataagg tggattttgt
     3541 ggttggtgtc ttgggagtct ttctggctca aggcttgaat ctcttgtttc tcaatgtcat
     3601 ctttcaacat attccattcc tagaaggctg gacctttcaa gagatagctt tcatttatgg
     3661 attttccttg attcccaagg gaatggacca tctctttttt gacaatctct gggcactagg
     3721 gcaacgccta gtccgaaaag gggagtttga caagtatctg actcgtccca tcaatcctct
     3781 ctttcacatc ctagttgaaa cctttcagat tgatgccttg ggtgaactct tagtcggtgg
     3841 tattttattg ggaacaacag tgaccagcat tgtttggact cttccgaaat tcctgctttt
     3901 cctagtttgt attccttttg cgaccttgat ttatacttct cttaaaatcg caacagccag
     3961 tatcgccttt tggactaagc agtcaggcgc catgatttac atcttctata tgttcaatga
     4021 ctttgctaag tatccgattt ctatttacaa ttctcttctt cgttggttga ttagctttat
     4081 cgtgcctttc gcctttacag cctactatcc agctagctat ttcttacagg aaaaggatgt
     4141 gttctttaac gtaggaggtt tgatgttgat ttctctggtt ttctttgtta tttcccttaa
     4201 actttgggat aagggcttag attcctacga aagtgcgggt tcgtaaaagc taaagtaaga
     4261 ctaaaatcaa gaaagaaact tatgatgttt gtaattgaag aagtcaagga tgaaaatcaa
     4321 aaaaaggcag ttgtagctga ggttttgaag gatttgccag aatggtttgg aatcccagaa
     4381 agcacacaag cctatataga aggaaccacg acactgcaag tttggaccgc ctatcaggag
     4441 agtgatttga ctagatttgt aagcttatcc tattcgagtg aagattgtgc agagattgat
     4501 tgtctcggcg taaaaaagct tatcaaggta gaaaaattgg gagccaattg cttgctactt
     4561 tagagagtga agctcgtaaa aaagttggtt atctgcaggt caaaacagtg gcagaaggtt
     4621 ctaataaaga ttatgatcga acaaatgact tttatcgagg tcttggcttt aaaaagttag
     4681 agatttttcc tcaactatgg aatccgcaaa atccttgtca gattttgatt aaaaagcttg
     4741 aataatatta cttgacatct attctcagag tgccatactg taagtgtaat cgccgattta
     4801 gctcagttgg tagagcaagg cactcgtaaa gcctaggtta taggtagata aacgactgag
     4861 gagttgaaaa aatagatagg tagaagataa ccgttaagcc ttattcttag cggttattta
     4921 tattgtttaa tagcgctgat atttcatcaa ttatgcctgt tttcgtgttt ctggtagttg
     4981 ttcaagttta ttgctactat ttttgatggt atgaatgtgc ttataatgta tcccggttaa
     5041 cgaaagtttt ggacttatac tctt
//
LOCUS       DAVAZV010000086         4862 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVAZV010000086 DAVAZV010000000
VERSION     DAVAZV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4862
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.086"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            98..1357
                     /locus_tag="VQT46_002026"
     CDS             98..1357
                     /locus_tag="VQT46_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET2371983.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQIQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1433..1568
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1607..2107
                     /locus_tag="VQT46_002027"
     CDS             1607..2107
                     /locus_tag="VQT46_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET2371984.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2183..2551
                     /gene="rplL"
                     /locus_tag="VQT46_002028"
     CDS             2183..2551
                     /gene="rplL"
                     /locus_tag="VQT46_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET2371985.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKTKLEEAGASVTLK"
     gene            2738..2908
                     /locus_tag="VQT46_002029"
     CDS             2738..2908
                     /locus_tag="VQT46_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371986.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2908..3156
                     /locus_tag="VQT46_002030"
                     /pseudo
     CDS             2908..3156
                     /locus_tag="VQT46_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3170..3510
                     /locus_tag="VQT46_002031"
                     /pseudo
     CDS             3170..3510
                     /locus_tag="VQT46_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3503..3883
                     /locus_tag="VQT46_002032"
     CDS             3503..3883
                     /locus_tag="VQT46_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET2371987.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3896..4039
                     /locus_tag="VQT46_002033"
     CDS             3896..4039
                     /locus_tag="VQT46_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371988.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
     gene            4132..4719
                     /locus_tag="VQT46_002034"
     CDS             4132..4719
                     /locus_tag="VQT46_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2371989.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQILYGSSLIS
                     FLWMYGQRKQAHKVNMKSRMKWLGVEFVSLLIISLCFSLIHAQGSTNQANLIGLQHQI
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHTGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLF"
BASE COUNT         1536 a          827 c         1034 g         1465 t
ORIGIN      
        1 agatagaact gacgaagtca gtaaccacac ctacggcaaa gtgaatctga agtggtttga
       61 agagagtaca acttgtcttt tagaaaagga gcctataatg aaagtctttc agcatgtaaa
      121 tatcgtgact tgtgatcaag atttccatgt ttatcttgat ggaatcttag cagtcaagga
      181 ttctcaaatc gtctatgtcg gtcaagataa gccagcgttt ttagagcaag ctgagcagat
      241 tatagactat cagggagctt ggattatgcc tggtttggtc aattgtcaca cccattctgc
      301 aatgacaggt ctgagaggga tccgagatga cagcaatctc catgaatggc tcaatgacta
      361 tatctggcca gcagaatctg agtttactcc cgacatgact accaatgcgg tcaaagaagc
      421 cctgacagag atgctccagt caggaacaac aacctttaac gatatgtata atcccaatgg
      481 tgtggatatc cagcaaattt atcaggtggt gaaaacttcc aagatgcgtt gttatttttc
      541 tccgactctc ttttcttcag agacagaaac aactgctgag actataagca gaactcgatc
      601 catcatagac gaaatcttaa aatataaaaa tccaaatttc aaggttatgg tagcacctca
      661 ttctccgtat agctgcagta gagacttgct ggaagcgagt ttggaaatgg caaaagagct
      721 aaatattccg ctccatgtcc atgtggcgga gaccaaggag gagtcaggaa ttatcctcaa
      781 acgatacggc aaacgccccc ttgcttttct tgaagaactg ggttatttag atcatccgtc
      841 cgtatttgct cacggggtcg aattaaacga gagagaaatt gaacgcttgg catcttctca
      901 agtggctatc gcccacaatc ctatcagtaa cctcaaactg gcatcaggaa ttgctccaat
      961 tatccagatc caaaaagcgg gagtagcagt cggaattgcg actgactcgg ttgcttccaa
     1021 taacaatcta gatatgtttg aggaaggaag gactgcagct cttcttcaga agatgaaaag
     1081 tggggatgcc agccagtttc caatcgaaac agctctcaag gtactgacaa tcgaaggggc
     1141 taaggtcctt ggaatggaaa atcagatagg aagtctggaa gtcggcaagc aagcagattt
     1201 tctggtcatt caaccacaag ggaaaattca tctccaacct caggaaaata tgctgtctca
     1261 cctggtttat gcagttaaat ctagtgatgt agatgatgtt tatatcgccg gagaacaggt
     1321 tgttaagcaa ggtcaagtcc tgacagtaga actttaaaag aaaaatcacg aaaaatttta
     1381 aaaaaagttt gcaaaaatct tgcattcttt ttttgactat gctatactta tatacggttt
     1441 aaaaaaactg cctaagacag taggggagct cgactcataa atatcctacc gaggacaaga
     1501 cgtatcatgt aaaaagaagc gtattgtact ttcgtgtcta ggtttgggcg cgtttttctt
     1561 tttgaaaaat tccccaagca aaataattac ggaggtgaac acactaatga gtgaagcaat
     1621 tattgctaaa aaagcggaac tagttgacgt agtagctgaa aaaatgaaag ctgctgcatc
     1681 tatcgtcgtt gtagacgctc gtggtttgac agttgagcaa gatacagttc ttcgtcgcga
     1741 gcttcgtgga agcgaagttg agtataaagt tattaaaaac tcaatcttgc gtcgtgcagc
     1801 tgaaaaagct ggtcttgaag atcttgcatc tgtatttgtt ggaccatctg cagtagcatt
     1861 ttctaatgaa gatgttatcg caccagcgaa aatcttgaac gacttttcta aaaacgctga
     1921 agcacttgaa attaaaggtg gtgcaatcga aggcgctgtc gcatctaaag aagagattct
     1981 tgcacttgca actcttccaa accgcgaagg acttctttct atgctccttt ctgtacttca
     2041 agcgccagtg cgcaacgttg ctcttgcagt caaagcggtt gcagaaagca aagaagacgc
     2101 ggcttaatct taagctacac agcgtagcct agctacgaaa aaaactatta taaaatttaa
     2161 aacttatttg gaggaaataa caatggcatt gaacattgaa aacattattg ctgaaattaa
     2221 agaagcttca atccttgaat tgaacgacct tgtaaaagct atcgaagaag aatttggtgt
     2281 aactgcagct gctcctgtag ctgttgctgc agctgatgca gctgatgctg gtgctgctaa
     2341 agattcattc gacgttgaat tgacatctgc aggcgacaaa aaagttggcg ttatcaaagt
     2401 tgtacgtgaa atcactggtc ttggtcttaa agaagctaaa gaacttgttg acggtgcacc
     2461 agcacttgtt aaagaaggcg ttgcaactgc agaagctgaa gaaatcaaaa ctaaattgga
     2521 agaagctgga gcttcagtta ctcttaaata atagagtatc gcaatttgat tgcggaatcc
     2581 ctatttacca gtctttgaga gcgataagcg attgatagaa actgataaat tgatttggtt
     2641 tcctgccaaa aattctttgg caggattttt gttttaataa actttcgggg gtagacacta
     2701 gattgtctac cccttttttt gtgtttcgga ggtaattatg caaaaggaag gacagtcatc
     2761 acgtcaattc gtgaagagtc atctcatgac tatcatggga gttgatattg taaaagcaac
     2821 tcagttagtt gatgaaatgg aacaagtagg tttaatccga tttgatgaat ttggaaatgt
     2881 tggaatttta gtcttggagg gacaataatg aagtgtatta ccgctaatca atatcagaca
     2941 tcagagcgtt attataagct ccccaaactt ttatttgaga gtgaacggta taagaatatg
     3001 aaactggagg ttaaggtggt ttactcagtt ttaaaagatc ggttggagtt gtctttgagc
     3061 aaaggttgga ttgatgagga tggggctatt tatttgattt attccaattc aaatttgatg
     3121 gcacttttag gctgttcaaa gtcaaaatta ctctccatgt gagtttgaag tgacattttt
     3181 agatgattac cataaaaaac ataactaccc actattttac gaatcctatc ttcaaaacgt
     3241 tatggaattc cttgaaagtc aagacataaa gaatggggtt gatgcctttg tagatgatca
     3301 tcaaaatctc gtttttgttt tatatggaca aggctatcga gccgagggaa aagagggaat
     3361 acttacaacc caagtaactg taaaagctta tgatgaagac aagaaaccga ttaacttcgc
     3421 aaatttatta gattccttaa tttattagat tccttaatcg tgtcagaata tcaaatggaa
     3481 ccgaatcttt gggaggtctc ccatgattga tctctatcta agtaaaaata gacaaagaaa
     3541 tcaacttctt ttagatttct tccaaaacta tggcatagag gtatcttgtc attcagtttc
     3601 tgaaatgaca aaggacaaat taattgagat gatgagctat tcttcagatt gttttgagtt
     3661 tttatctccc aatttattac gatttaagaa ccgtgacaat ctaagattaa cggatttcgt
     3721 tgagataatt ttaaaaaatc ctgaactaac catcagactt cctcttgcgg tttcaaataa
     3781 gcgagtttat ccaagtctga atttggaaga ggctagagct ctattgccaa gagatacgaa
     3841 acaattgatt tacatggcgc aaacacatta tttatctaac taaaggagaa gcaatatggc
     3901 tgaacgattt tgggagaact tgtccattat tttggctgaa agaaatatca gctggattga
     3961 gttaaccaga aaaatgtttg cgggagagtt tcactatcca agtgaattga atcgtttgta
     4021 tcaaaagatt cgccactaga agatggaaca atgaatgcct caaagtccat gggtagaaag
     4081 gattgtgcag gtattagatt tagattatga agatttattt cggaggtaac tatgaaaaga
     4141 ataattccag tttatatatt ccaacaagta aatgtcctat tggtatctct atacttattg
     4201 aaatttcttt gtatcggtga gttaactata ctacagattc tctatggttc gtcactcatt
     4261 tcttttttat ggatgtatgg ccaacgcaaa caagcgcata aggtcaatat gaaatctagg
     4321 atgaaatggc ttggtgttga atttgttagc ctactgatta taagtctatg ttttagtctg
     4381 attcatgctc aaggaagcac gaatcaagca aacttaattg gccttcaaca tcaaattcct
     4441 tggttttcat ttttattgtt cttaatcaat gcgagtatgg ttgaagaatt tctgtatcga
     4501 gaaattttat ggaatttggt cagaaaatta gatatcagag ttgctttgac aagtgtttta
     4561 tttgccttag cacatcatac aggaaccatt ctagcttggt gtttgtatgt ttcacttggg
     4621 atgtttttag gtatggtgcg ctataaatct gacttatggg gcagtatggg actacatttg
     4681 gtgtggaacc tactagttta tagtttgctg cttttttaaa ataggtgacc tgatttttag
     4741 gtaacttcta aaactaactt ccagttttgg gagagagatg gaagttactt tgaaaagtta
     4801 cggaaacatt attttctatg tgacaacatt gtataattgc ttgcatttta ctggtggaga
     4861 ga
//
LOCUS       DAVAZV010000087         4552 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVAZV010000087 DAVAZV010000000
VERSION     DAVAZV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4552
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.087"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(112..549)
                     /locus_tag="VQT46_002035"
     CDS             complement(112..549)
                     /locus_tag="VQT46_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET2371990.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLEAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQT46_002036"
     CDS             complement(634..3267)
                     /gene="polA"
                     /locus_tag="VQT46_002036"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET2371991.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAEGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIVVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3520..3873
                     /locus_tag="VQT46_002037"
     CDS             3520..3873
                     /locus_tag="VQT46_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET2371992.1"
                     /translation="MILRHLGISPTNDLVAKKIFSNPEITCQFIRDMLDLPAKNVTIL
                     EGSNIHVLPSMPYSAQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQV
                     NQNLEKIRQREGDTH"
     gene            4088..4204
                     /locus_tag="VQT46_002038"
     CDS             4088..4204
                     /locus_tag="VQT46_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET2371993.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            4197..4430
                     /locus_tag="VQT46_002039"
     CDS             4197..4430
                     /locus_tag="VQT46_002039"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2371994.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGRAERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1385 a         1096 c          837 g         1234 t
ORIGIN      
        1 gtatctacaa cctcaaaaca gtgttttgag cagcccgcga ctagtttcct agtttgctct
       61 ttgattttca ttgagtataa cacaaaaggt agcccatcag ctaccttttt cttatgcttc
      121 ctcaatcaag cgagtatgtt ctctcttgat acagcgattc atcacgatat catcacatcc
      181 accatcacgc aaaatctctt tcgcttctaa actttcaagt cctagctgtg cccaaaaaat
      241 cttggcatca gctttgagaa aatcacgcgc cacatcgggc agaaattcac tgcgacgata
      301 aacattgaca atatctacag gaaaaggaat ttcagcgagg ctagcataag ccttttcacc
      361 caagatttcg ccacctgccg ccttgggatt gactgggatg attttatagc cccgagcctg
      421 catttccttt gtcactcgat tgctggttgt ttcttcacgg tcagacaaac ccaccacagc
      481 aagggtttta ctcgttgcga gatactgacg aatcacgcca tcacttggat tgataaattc
      541 ttgactcata gaaaacctcc tttttcatca gtatagcaca ttttgaaaag gtttgcagaa
      601 ttctactaca aaaaaggagg actagccccc tttttattta gcctcgtacc aggttgcccc
      661 ttcattctca tctgcgataa gaggaacact gagttgaatg gcttcttcca tggtttgttt
      721 caccaatttt ttcatctcta ccaattcaga tttaggcact tcaaggacga tttcatcgtg
      781 cacttgtaac agcatcttag tctgataacc acctgcaacc aaggctttat ccagctgaat
      841 catggcaatc ttgagaatat ctgctgccga accctggata ggtgagttga tagcagttcg
      901 ctccgcaaaa ccacgaatat tgaagttgcg cgaattgata tctggcaact cacggcgacg
      961 cttaaagagg gtctctacat agcccttatc acgcgcctcc cgcaccactt catccatgta
     1021 gtttttaata cctggaaaac gttcaaagta ggtatcaatg taggctttgg cttccttacg
     1081 actaattccc aaattattag acaagccaaa gtctgaaatc ccataaacca ctccaaagtt
     1141 aactgccttg gcattgcgac gatcatttgc agtcacatta tcaggacgct caatgccaaa
     1201 gacccgcatg gctgtcgaag tatggatatc tgccccctct tggaaggcct taatcaagtg
     1261 ctcatcctta gaaatatgcg ccaaaacgcg caattcaatc tgtgaatagt cagagctgag
     1321 tagcacacta tcctcccact ctggcacaaa agccttccga atcaagcgcc cttgttccaa
     1381 tcgggcagga atattttgca agtttggatc cacactagac aaacgcccgg tctgggtcaa
     1441 atcctgcata tagcgagtat gaatctttcc atcagccaaa atccagtcct gcaagccaat
     1501 tacataagta gattgaatct tagcaatttg acggtaatcc aggattttct taacaatcgg
     1561 agcaatagga gcgagacgct ccaacacatc cactgctgtc gaataacctg tcttggtttt
     1621 cttagtgtat tctagaggaa gtcccaattt ctcaaagaga agcacgccca actgcttagg
     1681 cgagttgaca ttaaactcct caccagccag ctcgtaaatc tcttgagtca gtttttcaat
     1741 gacaagctca ttttcagcct gcatctcaag caaggtctct ttcttgacca caatcccagc
     1801 aatttccatc ttggcaagaa caaaagccag aggttgctcc atatcataaa gaagctctaa
     1861 ttgcccattt tcgctgagtt tttcaagtaa aataggctct gtttctacca aaacagcaag
     1921 tttacaagct aagtgttcca agaatttctc acgttcagga atggcctttt taacaccctt
     1981 accgtagaaa gtttcatcat caaccaagta agtctgacca taaagactag cgatggtcgc
     2041 aatttcattg tcctccacag tcgaaaggag gtatttagcc aaacggatgt caaaagcagg
     2101 cgcctgcaaa tccacaccaa aacgttgcaa aagaacttta accttcttaa agtcataaac
     2161 tctcagagat gttttttcta agaaatcctt gaaaatcggg tcttgcaaca gctcaagctt
     2221 gtctgtggca tagagcttat ccccacaaga ccaggcaaat ccaaccaaat tatccgtatg
     2281 ataattctca ccaaaaagct caaagtggaa gatagactct tcactcagca tatcttgact
     2341 gatttggtca acaatagtaa aatccaaacc ctcagccaca tcagctgacg acacatttaa
     2401 agcctgcttg agctgtttga atcccatctc atcgtaaaat ttcccaagat tttcaacatc
     2461 tggaccacta tagaccaagt cctctaaacc aatcgcaatc ggtgccttgg tatcaatggt
     2521 cgctagtgtt ttagacaaaa aggcctgttc cttgtcattg atgagatttt ccttcatctt
     2581 agaagtcttc attccatcaa tattttcata aatcccctca agcgaaccat gctccagcaa
     2641 gagcttaata cccgtctttt caccgacttt ggtcacccca gggatattat ccgacttatc
     2701 acccatgagc gccttgagat cgataaactg agctggtgtg aggcccattt cttccatgag
     2761 gtaatctggc gtaaaggcct caaactcagc cacacctttc ttggaaattt caaccaccgt
     2821 atgctcatcc gtcagctgaa tcaaatcctt gtccccactg acaatggtaa tatcaaaacc
     2881 atcctgctct gctagcttat ccaacgtccc aatgatgtca tccgcctcat actgagccag
     2941 ctcatagtga cgaatcccca tatgatccag caactcacga atgaaaggaa attgctcacg
     3001 aaactcatca ggagtcttgg cccgaccacc cttatagtcc gcatacatct ctgtccggaa
     3061 ggtcgtcttt cccgcatcaa aagccaccaa aatatgactc ggctcaaccc gctccaacaa
     3121 atgactcaac atcaactgaa aaccataaat cgcattggta tgcaaaccag ccgcattctt
     3181 aaaacggtcc aactgctgat acagcgcaaa aaacgcccga aaagctacag aagacccatc
     3241 aatcaataat aattttttct tatccataca cccattataa aggaaagaat caaaaaatac
     3301 cattgggaag agctagagca agtatttttc aaactttttc cgaataaata gatagagcca
     3361 gagaatttag taaacctaga tttaaaaatg tgctataata tagtatattg aatctataat
     3421 agtacacctt gactgctaaa atatttctat aaattaattt gactttcctg atagagttgt
     3481 tcacatctta tttcaattca ctatagaagg aggaaaagga tgattctcag acatctggga
     3541 attagcccga ccaatgactt ggttgctaag aaaattttca gcaacccaga aatcacttgt
     3601 caatttatcc gcgatatgct ggacttgcca gccaaaaatg tgactatttt ggagggaagt
     3661 aacattcatg tcttgccttc catgccctac tcagcgcagg atttttatac cagtatagac
     3721 gtcttggcgg agttggataa cggtactcaa gtaattattg agattcaagt ccatcatcag
     3781 aattttttca tcaatcactt gtgggcttac ctgtgcagtc aggttaatca aaatcttgaa
     3841 aaaattcgtc agcgagaagg tgatactcac tagatctaca aacacatcgc tcctgtttac
     3901 gtcattgcta tcgtggatag taattatttc tcagatgacc tggcttttca tagctttagt
     3961 atgcgcgaag acacaacagg tgaggtattg gcgattacca acaatggaca ggaaaaccat
     4021 ctggttaaga tggcattctt ggaattaaaa aatacagaga aaccagcaaa gacaaggttc
     4081 gcaagccatg gttggagttt ttcggcaaca agccctttac ccagcaaccg caacgagcca
     4141 ttacccaagc aaatcaactg ctggactaca agagctggtc cgaggaggac aggaaaatgt
     4201 ttagtcaact acatatgcga gaagaacaag tcttgttagc acaggactat gccttggaaa
     4261 ctgctagggc tgaaggcctt gaacaaggac tagagcgtgg gaaagttgaa ggaagggcag
     4321 aaaggaaact ttttgccttc ctagacatag tacgccaagg tcttctgact tctgaggttg
     4381 ccagccagca attaggtatg tcagtatctg aatttgaggc actgttgtaa aatggctcca
     4441 taatatccat agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa
     4501 aaagtcccat atgacctata atgaaaagcg acaaaacaac tcattaaaaa ga
//
LOCUS       DAVAZV010000088         4438 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVAZV010000088 DAVAZV010000000
VERSION     DAVAZV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.088"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..119
                     /locus_tag="VQT46_002040"
     CDS             <1..119
                     /locus_tag="VQT46_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET2371995.1"
                     /translation="QQGFTDRLVGYSSSIALVFTTLIGMISLVQRRVLKEDD"
     gene            121..966
                     /locus_tag="VQT46_002041"
     CDS             121..966
                     /locus_tag="VQT46_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET2371996.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            976..2295
                     /locus_tag="VQT46_002042"
     CDS             976..2295
                     /locus_tag="VQT46_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET2371997.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGGEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWREKRFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(2503..2575)
                     /locus_tag="VQT46_002043"
     tRNA            complement(2503..2575)
                     /locus_tag="VQT46_002043"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2540..2542),aa:Lys,seq:ctt)
     gene            complement(2839..4110)
                     /locus_tag="VQT46_002044"
     CDS             complement(2839..4110)
                     /locus_tag="VQT46_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET2371998.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYAARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWIKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDRLRKI"
BASE COUNT         1294 a          809 c          976 g         1359 t
ORIGIN      
        1 atcaacaagg ttttactgat cgtcttgtag gatattctag ctcaatcgct ttagtattta
       61 caacgttaat tggtatgatt agcttagtac aacgtcgcgt tctgaaggag gatgactaag
      121 atgaaacgat ttaaaccaac aacaatctta gaatatattc tgttaacttt attggcagga
      181 ctcttccttt ttcctatggt ttggatggta gtttcagcta tgaagccaga agcggatgtt
      241 tataaaaatt tgactagttg gcaagccttc ttaccaagtt taaatcccgc tgattggttt
      301 aaaccttatc aggaagtatt tgagcgcttt agtattttta catatctagg gaacagcatt
      361 ttttatgctg gaacgtttgc tattggttct attattgtca atgcactggc cggtttcgct
      421 tttgcaaaag tcaatttttc aggtaagaaa attttatttg gtttcttact tgctttactt
      481 attattccag tggaaactgt gttaattcca caatttacca ttatcaattc cttaggtttg
      541 gtcaataatc gtcttgcagt tattattcca ggattggcga gtgtatttaa tatttactta
      601 tttaggaatt tctttattgc aattccagaa gagattcttg agtctgcaaa gatggacgga
      661 gcaagtatcg ttagaatttt ctttagaatt atgcttccaa tgtctaaacc tgcagttgct
      721 acagttggtg ttttatcatt tatttcaagc tggaatgatt atatctggcc attgatggtt
      781 ttgacagatt cttctaaatt ttcaatgcag gttgcaatta caactattaa tacaactcaa
      841 ccagtttata tcaatcaggt aatggctgta ttaactattt caacgattcc gttgattttg
      901 gtctatgtag tcgctcagaa atatattgtt caaggtctgg gtggttccgg aactggaata
      961 aaataggata tacttatgat aaataaaaca tttacagtag aaaaagccaa tcgttttata
     1021 gcagaaaata aacatctcgt taatactcaa tataagcctg aagaacattt ttcagctgag
     1081 attggttgga tcaatgatcc aaatggattt gtctattttc gtggagaata ccatctcttt
     1141 tatcaattct atccatatga tagtgtttgg gggcctatgc actggggaca tgctaaaagt
     1201 aaggacttgg tgacttggga gcacttgcca gtggcacttg ctcctgacca agattatgac
     1261 cgaaatggtt gtttctcagg ctctgccatt gtcaaggatg atcgcctctg gctcatgtac
     1321 actggacata tcgaagaaga aaccggtgtc cgccaagtgc aaaatatggc attttcagat
     1381 gacgggattc actttgaaaa gatttcccaa aatccagttg caactggatc agacttgcca
     1441 gatgagttga ttgctgctga tttccgtgat ccaaaactct ttgaaaaaga tggacgctat
     1501 tactccgtag tagctgccaa acacaaggat aatgtgggct gtatcgttct actagggtcc
     1561 gataacctag tagaatggca gttcgaatcc atctttttaa aaggaggaga acaccaaggc
     1621 tttatgtggg aatgcccaga ttacttcgag ttagatggga aagattgcct tattatgtca
     1681 cccatgcgtt atcagcgtga gggagactca tatcataaca tcaactcatc gcttttgttc
     1741 acgggtaagg tagattggag agaaaaacgt tttatcccag aatcagttca agaaattgat
     1801 catggccaag acttctatgc gcctcaaaca ttgttggacg atcaaaatcg tcgtatcctg
     1861 attgcttgga tgcagacatg ggggcgtacc cttccaaccc atgaccaaga acacaaatgg
     1921 gcatgtgcca tgactttacc tagaattcta agattggaag atggcaaact aagacaattc
     1981 cctgttaaaa aaggccaata tcaaatccaa atagataaag attgtcatta ccacttagga
     2041 aatgatacag attatcttga atttggttat gacagtaatg cgcagcaagt ttacattgat
     2101 cgtagccatc ttattcaaaa aattctaggt gaagaagaac aggacactag tcgacggtat
     2161 gtagatattg aagctaaaga attggaagtt gttctagata aaaattccat cgagattttt
     2221 gtcaatcaag gtgaagcaag cttgactgca acttattact taacggtgcc agctgagcta
     2281 tcacgaattg attaaaaatt aagttatttc tcctaaagaa aaagttctct ttctaaaata
     2341 gtggaaagag gactttttgt gttttgggta tataagctta gtttatggta tttgtaaaat
     2401 tggtgttgga ttatgattta agctagtttt ctaaagaatt tgaaaaaaat tttatttaag
     2461 caaaaaaacc ttggttccaa ggcttttcct gttgtattta gatgccccct acagggatcg
     2521 aacctgtgac ccacggatta agagtccgct gctctgccag ctgagctaag gaggcaaaga
     2581 aaaagctgta ttggtgccga aacttcacgg tttgtattga acccgcgcaa ttaagcaggt
     2641 gggcaactcg ctctaactga agctgtttcc gtgtgagacg gcctacatgc tgttagaaga
     2701 cttttgtttc cctaataata caaaaaatag tcggtcaaca cttaagtgtg aagtcgtaca
     2761 ccacagcgtt tctatactta tatgatacca ctttttcaaa aaaaatcaag aggaaagtgc
     2821 aattttttga aaaggatttc agatttttcg caaacgatcg atagcttcct ttctttgagc
     2881 caaagcccgt tcatatttac cagtatcttc tgcttggaaa tagtgatgat tacgaatttt
     2941 ttctggcaga tagtcttgct tgatccaatt tccaggatag ttgtgtggat agagatagtc
     3001 ttgggcattc cccagttcct tgcttccact gtagtgccca tcacgcaggt gtcgcggaat
     3061 aggcaagtgc cctgatgttt tgaggtcagc aagtgcctta tccatagcta cataggctga
     3121 gttggatttt ggagaaaggg ccaaatcaat cacgacattg gcaatgagaa tgcgggcttc
     3181 ggggaaacca atcctttgtg cagcatccag agcagtcacg gtatgaatct gggcctcagg
     3241 attggctaag ccaatatctt cataggcgat aacagtcaag cgacgagcga gactaggcag
     3301 atccccagcc tcaatcaagc gggcagcata gtggagactg gcatccacat ctgagccacg
     3361 gatagacttt tgcagggcag atagaacatc atagtgaccg tctccatcct tgtccatagt
     3421 gatgtagctt ctctgaagac tattttccat gatgtctaag gtgatgtggc gaatgccctc
     3481 gtcattctca ggggtagaga gaacagccaa gtccagtgag ttaaaggcag agcgaaggtc
     3541 tccgtttgta gaggttgcga tgaaatccag cgcatcctca tctagttcta ttggaaaatc
     3601 aaaaccacgt tcagggttac ttagagctat ctgcagggcc tctttgacgt cttggttaga
     3661 cagaggttcc aactcgaaaa tttgaacacg gctacgaatg gcaggagtga cagagaagaa
     3721 aggattttca gtcgttgctc caatcatgat gaccagtcca ctttccaaga gaggcaagag
     3781 gaagtcttgc ttggtcttat ctagtcgatg aatttcgtct agcaatagga cgagaccacc
     3841 agaaaattta gcttcttccg agatttcttg cagtcgcttt ttactatcaa ctgtcgcatt
     3901 gaaagttcga aaggcatact tggtcgttcc agcgatggca gaggcaatac tggttttgcc
     3961 gattccagga gggccatata gaatcatgga ggacaggcgg ttggcttcca ccatgcggcg
     4021 gatgattttt ccaggtccga ccagatgctc ctgaccgatg acctggtcga tggttttagg
     4081 gcgcatgcga agcgcgagat tgtctggcat agcagtcctt tctaacgtgg atttgagtag
     4141 aatgactcat ctactatatc ttactatgtc cattctagcc tattagttgt gatatttcaa
     4201 tggttttgta ataatcaggg agtgagatag aatctttttt actatttaat ttaatgagga
     4261 gaggtatcag catgagagat ttgattttcc ttaaagctca aaataggata gttgagccta
     4321 aagaagtgga agtgctgact tgagaaataa tattgctgaa tgtcattgta tgaactataa
     4381 tgaaaagaga ggtgataagc aatggaaatg atggaccaag tcaggaaatt ttgatttt
//
LOCUS       DAVAZV010000089         4423 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVAZV010000089 DAVAZV010000000
VERSION     DAVAZV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4423
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.089"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQT46_002045"
     CDS             complement(56..1066)
                     /locus_tag="VQT46_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET2371999.1"
                     /translation="MSFLSKNGAGILACLLISIVSWYLGGFFPVIGAPVFAIFIGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVVLLGFGLNISQVFAVGQSSLPVILSTISIALI
                     IAYLFQRFFALDTKLATLVGVGSSICGGSAIAATAPVIDAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNEGFALFAGTAVNDTSSVTAAASAWDSLYQSNTLESATIVKLT
                     RTLAIIPITLFLSYWQSRQQENKQSLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKELSKFLIVMAMSAIGLKTNLVAMVKSSGKSILLGAICWIAIILTTLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQT46_002046"
     CDS             1215..2384
                     /locus_tag="VQT46_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET2372000.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQVISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQT46_002047"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQT46_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET2372001.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQT46_002048"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQT46_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET2372002.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQT46_002049"
     CDS             4146..4379
                     /locus_tag="VQT46_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET2372003.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQSVGDVVKIIQGK"
BASE COUNT         1286 a          842 c         1135 g         1160 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtgttaga
       61 aaatgccgat aagggtctgc ataccaagag tggtgaggat gatggcaatc cagcagatgg
      121 ctccaagaag aatggatttt ccactggatt tgaccatagc gaccagattg gttttgagac
      181 cgatagcact catggccatg acaataagga atttagagag ttctttgaga ggggtaaaga
      241 aactactgga cacacctaga gaggtgagta gtgtagtgag gagagaggca aggataaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaggct ttgcttgttt tcttgttggc
      361 gactttgcca gtaggagaga aagagcgtga tagggataat agccaaagta cgtgtgagtt
      421 taacaatggt tgcagactcg agggtattgc tttggtaaag actgtcccaa gcgctggcgg
      481 cagccgttac agaggaagtg tcgttgaccg cagtccctgc aaagagggcg aagccttcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggaaatggct tgggctactt ccttttcctt agcatcaata acgggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaaccaag gtagccagtt
      721 ttgtatccag tgcaaagaaa cgctggaaga ggtaggcaat aatcagagct attgagatag
      781 tggacaggat gacagggagt gaagattggc caactgcgaa gacctgcgag atattgagac
      841 caaaaccaag caagacaacg gcatattgga gcaacttctt ggaactaaag gtcaaaccag
      901 catccagttg tttataggac gagagaaagg gatgtaggag catgcctatg aaaatggcaa
      961 aaacgggcgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcaggc caagatacct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 aaaatctatt accattatag acctataaac aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcggggggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggtta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ccagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaattttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggc ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga ggccttggca gctgttttac
     1801 gcaagtacga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccaggc tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcggccttca
     1981 cagcccagtt aatcaagagt caccaatact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaatgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggcagcagg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct ggactcatgt ctaccttgcc taccgttgat
     3541 ggaaaaggtt ttgacatgct agaccttggt gccaatgcag aaaatacagc ccagcacctc
     3601 catcaatatg cggttctagg ttccttctat gctaaaaatg tccgtggcat tgcgcaacca
     3661 cgcgttggtt tgctcaacaa cggaacagag agtagcaagg gcgacccgct tcgtaaggaa
     3721 acttatgaat tactggcggc tgatgaaagt ttgaacttta tcggaaacgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacagc tcaattattc agatgttggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aggaaattga ccaactccaa agtgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aat
//
LOCUS       DAVAZV010000090         4286 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVAZV010000090 DAVAZV010000000
VERSION     DAVAZV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.090"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..141
                     /locus_tag="VQT46_002050"
     CDS             <1..141
                     /locus_tag="VQT46_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2372004.1"
                     /translation="LLPLPPYSPEYNPIEKTWAHIKKHLKKVLPSCNTFYEALLSCSC
                     FN"
     gene            complement(134..307)
                     /locus_tag="VQT46_002051"
     CDS             complement(134..307)
                     /locus_tag="VQT46_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET2372005.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(465..2072)
                     /locus_tag="VQT46_002052"
     CDS             complement(465..2072)
                     /locus_tag="VQT46_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET2372006.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIAAIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            2225..3709
                     /locus_tag="VQT46_002053"
     CDS             2225..3709
                     /locus_tag="VQT46_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET2372007.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFLNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGISPADRKVAVVARQKAEETGGPALALELPNGDIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            3804..4286
                     /locus_tag="VQT46_002054"
     CDS             3804..4286
                     /locus_tag="VQT46_002054"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET2372008.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1242 a          986 c          811 g         1247 t
ORIGIN      
        1 cttttacctc ttcctcccta ctcacctgag tacaatccta ttgagaaaac atgggctcat
       61 atcaaaaagc acctcaaaaa ggtattacca agttgcaata ccttttatga ggctcttttg
      121 tcttgttctt gtttcaattg actatattat cagtgtaata gtctaataga tagttaaatg
      181 tagttggatt tccactaaag gttgatgagt aagtttttgt atctgaacct gattggccgc
      241 aagcagctaa aagcaaaaca gatgcaaaag tcaggcctgc actaaggaca cgcttcttta
      301 tgttcatctt ctttctcctt aatagtggga atttgtaaag ttaattgaat ttcgagaatg
      361 aaagtttata aaccttggtt ataaaaaaca aaggatttct gcttttatac agtcctccct
      421 tgtttttata tgatttcaat tttaaatttt tctgcaaaaa atatttatag taattccaca
      481 cagaaagcat cccatggaac taagatttgt ttttcaaaga cttcttgagc tagggtgttt
      541 tcaatcaaga cagatttgac ttttccttct actgtcaagt cttgctcttc attggacaag
      601 ttagccacaa ctaggaagcg acggtcgcca tccttacgta tataagcaaa gaccttatca
      661 gccgtatcaa gcaattcaaa gtcagctcga actagccagc tattctcctt gcgaatttgg
      721 accagtttct gataggtata gaaaatagaa tctggatttg ccagcgcttc ttggacattg
      781 atcatctcgt aatttggatt aaccgccaac caaggttgac ctgttgagaa accagcgttt
      841 ttgctctcgt cccattgcat aggggtacgg gcattgtcac gtccaataac acggatactg
      901 tccatgattt cttcaatcgg aacacctttt tcaagagcct cacgcgcata gttgagagat
      961 tcaatatctt ctacttgatc cagtgtttca aacggatagt tggtcatccc aatctcctca
     1021 ccttggtaga tataaggagt tcctctcata agatgaagca agattgcaaa ggctttggca
     1081 gatttttcgc ggtattcttg gtcatttccc cagattgaga caatacgagg gaggtcatgg
     1141 ttgttccaga agagggaatt ccagccgtcc tcaactccta actctgtctg ccatttgttg
     1201 aagatttctt ttaacttagc gatattcagc tctttttgat agtgccattt aggctgacct
     1261 tcctgatact gaagaccgat atgttcaaac tggaagacca tagacaattc ttgccccttt
     1321 ggatcagagt agagcttggc aatctctggc gttgctcccc aagtctcccc tactgtcaag
     1381 agatccttat ctccaaaggt cgcctgattc atttccttga gatagggatg gagcatagga
     1441 ccattattga ctaccttctc gtcaggaatt ttgccaatca tgtcaataac atccatacgg
     1501 aaaccaccaa tacccttatc aatccagaag ttcatcatct cataaatttt ctggcgaagt
     1561 ttttcatttt cccagttgag atccggctgt ttcttgctga aaaagtggag atagtattga
     1621 cctgactttt catcgtattc ccaagcagac ccactaaaga tagaatctaa atcgttaggc
     1681 tcatcccgcc agatatagta gtctcgctca gggctattag gattttcaca ggcctctaca
     1741 aaccaggcat gctcatccga ggtatgattg accaccaagt ccatgatgat acggatatca
     1801 cgcttcttag cttctgcaat cagctgatcc atgtcctcca tggttccaaa aatagccgca
     1861 atcgcttgat aatcagcaat atcgtagcca ttatcatcca tagggctgtc ataaacggga
     1921 gaaagccaaa ttgctgtgat tcctagcttg gctagatagt ccaacttact ggtaattcct
     1981 ggcaaatcgc caattccatc tccattacta tccataaaac tctttggata gacttgatag
     2041 actacggcat tatgccacca tttttcttgc atctgtttac ctcattattt tcataatcta
     2101 tagtctatga tagcactttt taaaattttg tgcaagcgtt tgcttaatct ttttaatttc
     2161 ttttttagct ccgtagtttc ctaacttcca attttttatt ataatagagt ccagaggtaa
     2221 aaaaatgaaa aaacaagctt ttagttctga acagtatttg aatttacaac gcgaccatat
     2281 tttggagcgc attaaccaat ttgacggcaa gctctactta gagtttggcg gtaaaatgtt
     2341 agaagatttc cacgctgctc gtgtccttcc tggttatgaa cctgacaaca aaatcaagct
     2401 cttgcaagaa ttgaaagagc aggttgaggt tgtgattgcc attaatgcta gcaacattga
     2461 acattccaaa gcacgtggcg acttgggcat ttcttatgac caagaagttc ttcgtttgat
     2521 tgacaaattc aatgaattag ggatttttgt tggttccgtt gtcattacac aatacgctgg
     2581 ccaacccgct gcagatgcct tcctcaacca acttgagaaa aacggaattg attcttatct
     2641 tcattatcca atcaaaggat atccgacgga tatggatcac atcatttccc cagaaggcat
     2701 gggcaaaaac gactacatca aaaccagtcg caacttgatt gtcgtaaccg ctcctggacc
     2761 cggttctgga aaattggcaa cgtgtatgtc caatatgtac cacgaccaaa tcaatggcat
     2821 caagtctggc tacgctaaat ttgaaacctt ccctgtttgg aatcttcccc ttcatcatcc
     2881 agttaacttg gcttatgaag ctgccacagc tgaccttgat gatgtcaaca tgattgaccc
     2941 cttccatctt caaacctatg gagaaaccac tgtcaactac aaccgtgata tcgaaatctt
     3001 cccagtgctc aagcgcatgt tggaacgtat tctcggaaaa tcaccatacg cttcaccgac
     3061 agatatgggt gtcaacatgg ttggtttcgc tattacagat gacgaggctg ctgtcgaagc
     3121 ttctaaacaa gaaatcatcc gccgttacta tcaaacagtt cttgacttca aagctgaaaa
     3181 agttggcgaa gctgccgtca agaaaattga gttgctcatg aacgacctcg gtatctcacc
     3241 tgcagaccgt aaggttgctg tcgttgcgcg ccaaaaagca gaagaaactg gcggaccagc
     3301 cctagctctt gaattaccaa atggtgacat tgtcactggt aaaaactcag aactctttgg
     3361 ccctacagcc gctgccttga tcaacgccat caaaaaatca gctgacatcg ctaaagaagt
     3421 aaaactaatc gagcctgaag ttgttaagcc aatccaagga cttaaaatcg atcatctcgg
     3481 tagccgcaat ccacgccttc attcaaatga aatcctgatt gcacttgcta tcacagctac
     3541 agaaaatcct gatgctgccc gcgctatgga agaactcggc aacctcaaag gaagcgaagc
     3601 ccactcaacc atcatcttga ctgatgaaga caagaatgtc cttcgtaaac tgggtatcaa
     3661 cgtaaccttt gacccatact accaatacga ccgcttatat cgtaagtaaa gatttcaacc
     3721 tctccagcct cggagaggtt ttctctctgt ctcaggagca agctttatga tataatgaga
     3781 gaagaaaact gaaaggattt accatgtcaa aagaagttat tgtcgaaagt tttgaacttg
     3841 accacaccat tgtcaaagca ccctatgttc gcttgattgg ggaagaaaca ggaccaaaag
     3901 gagacatcat ctccaattat gatattcgct tggtgcaacc aaacgaagac tctatcccta
     3961 ctgccggcct tcacactatc gagcacctct tagccaaact catccgtacc cgcattgacg
     4021 gcatgattga ctgttcacca tttggttgcc gcacaggctt ccacatgatt atgtggggac
     4081 gtcacaccag tgctaaaatc gcagctgtta tcaaggattc gctcaaggaa atcgctgaaa
     4141 ctactacttg ggaagatgtc ccagggacaa ccatcgaatc ttgcggaaac tacaaggacc
     4201 acagcctctt ctctgctaaa gaatgggcaa aactcatctt ggaacaaggg atttcagatg
     4261 atgcctttga acgtcatgtg atttaa
//
LOCUS       DAVAZV010000091         4124 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVAZV010000091 DAVAZV010000000
VERSION     DAVAZV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.091"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..370)
                     /locus_tag="VQT46_002055"
     CDS             complement(<1..370)
                     /locus_tag="VQT46_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2372009.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYKLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSG"
     gene            complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQT46_002056"
                     /pseudo
     CDS             complement(446..1297)
                     /gene="rfbD"
                     /locus_tag="VQT46_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQT46_002057"
     CDS             complement(1363..2412)
                     /gene="rfbB"
                     /locus_tag="VQT46_002057"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET2372010.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2422..3018)
                     /locus_tag="VQT46_002058"
     CDS             complement(2422..3018)
                     /locus_tag="VQT46_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET2372011.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQT46_002059"
     CDS             complement(3019..3876)
                     /gene="rfbA"
                     /locus_tag="VQT46_002059"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET2372012.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKAYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
BASE COUNT         1170 a          942 c          743 g         1269 t
ORIGIN      
        1 aaccactccg acgctgatca tggtggtaca gcgtgattgc ttgattctca gctttcccag
       61 acaaaaaagt ccaatagtag gtcagatggc tatcactctc tagaacccga taagaggttt
      121 catccgcatg aagaagaggt tgttctaaca acttttctcg taaaagctta taaagggact
      181 ctaaatagta ttgacttgcc ttgatatgcc aattagagat ttccttacgt gtgattggta
      241 aacccatcct agcccaatct tcttcttggc gataattggg taccttcaga ttaaacttct
      301 gatggatggt gtgagcgata atagaaactg agccaaagct atgcaccaaa gagaccagca
      361 ccaacaacaa gataattgta catcttaagc tcctttggag ttcattatct gcctctttta
      421 ttagactaga aaatcattct actacttatc tcacttcttg tttgtaaaat tcttgcaatg
      481 catcttgcca agttggaata acaaatccag tagctttggc tttggccagg ctcatcgttg
      541 agtttagcgg acgttgagct ttggctggaa attgactgga atctactggc ttgacttcga
      601 catctgtatc tttcaaaatt tcaactgcaa aatcatacca tgttgtgtct tctgtcgcat
      661 catttgacaa atgataataa ccaaattcct tacgattttc agctaggtag atcatgaatt
      721 cagccaaggt acgagtccaa gtcggacgac cgtactggtc atttacaact gttaaagtct
      781 tatgagtttt cgcaagattt tgcatggtaa aaacgaagtt tttgccataa tttccaaata
      841 cccaggcagt acggataata tagaaattag acacatgctt ctcaactaac tcttccccca
      901 tacgcttagt gcgtccatat tctgtctgtg gatctggtcg gtcatcaact tcccactctt
      961 gtccaactgg tttcttaccg tcaaagacct agtccgtaga aatataaact agagttgcac
     1021 catgcttttc agatgctttt gcgacatttt ttgtccccat cacattgatg gcgaagtcca
     1081 actcttttcc ttcatcctct gctgcatcaa cagcggtgta ggctgcacaa tggtagacta
     1141 aagtcggttt cacctcttca aaaactttct caaccatttc ttcattggta atgtccatct
     1201 cagccacatc tactgccacg tattcttcat tacgttcatc caataaatag cgaagttccg
     1261 ttcctaattg gccatttgcc cctgtaatta aaatcatctc tagacctttc taatatgtaa
     1321 ctcttcccaa tatagcaata aaaagcagcg atttcctgct ttttatactg taataatctc
     1381 ctgagtctta gcataattgg cttcaacagc ttctttttct gctttccacc attcttggtt
     1441 atctgtatac cacttgattg ttgccttgag cccagcttca aagttggtaa attcaggttt
     1501 ccaccccaac tcatcacgga gcttgctggc atcaatcgca tagcgaaggt catgtcctgc
     1561 acggtcagtc acatgatcat aggcatccgt agcttgtccc atttccttaa ggataagttc
     1621 caaaacttcc ttattgttct tctcaccatc agccccaatc aagtaggttt caccgatttg
     1681 cccttttgtc aagattgtcc aaactcctga agaatggtca ttggtatgaa tccagtcacg
     1741 aacgttctta ccttcaccgt aaagttttgg cttaattcca cttaggatgt tagtaatctg
     1801 acgtgggatg aatttttcga tatgttgata aggaccgtag ttatttgaac agttggaaat
     1861 cgttgccttg actccaaaag aacgcaccca ggctttgaca atcaagtctg atgcggcctt
     1921 ggttgatgag tacggagagc ttgggttgta ttttgtttca gcagtaaatt tctcacctgg
     1981 tccttcacca tgacctggca aatcttctcg taaagggaga tccccataaa cttcatctgt
     2041 cgatacatgg tggaagcgaa tatcatactt acgagcagct tctaaaagag tatagattcc
     2101 aatgaagtta gtatgaataa atggcgatgg atcattgagc gaattatcat tgtggctttc
     2161 cgctgcataa tgaacgatag catctgcttg agcaaccaac ttgtctacca actccgcatc
     2221 agcaatgtca ccaacaacta actcaacacg attgcctaaa atttcctcaa tattcgcgcg
     2281 gtttccagca taagtcaact tatctaggac tgtcacgtga acatctggaa agttctcgta
     2341 aacataatgg acaaagttag aaccgataaa gccagctcca cctgtcacga taatattttt
     2401 gtattcagtc atattctttc cttattccaa atcttctttt ttcaaaggct tcacgtcctt
     2461 aagtagggga tgatgtttgt ctgcttcaga tacgtctgct tcttccagat tttcccattc
     2521 aataccaagg cttggatcag cgtagttcac aaaggcatac ttgggtttga gttcaagagc
     2581 ccagtaatca ttgaccagat agctatatga cactgtatct gataaaactt ggaagccatt
     2641 agctacgcct cgaggaacaa agattccctt gcttgcatca attactgtct gataggtatt
     2701 cccaaaggtt tcaccctcgc gtagatcaac ccaagaaccc agaactttcc ctccatctgc
     2761 tacagagatg tacttatccc aaggctctgc gtggaggcct cgaaggacat ttttacgtga
     2821 gaaggataca ttgttttgca attttccttc tgcaaagaaa gactctggaa atccaagtgg
     2881 aagcactttt tccttttgga aattttcttt aaaccagcca cgattatctc catgaacggg
     2941 gatatcaaac tccaacatgc ctggaatagc ttcaaccttg cgtgccgcaa gcgtcttacc
     3001 gaaaaaatta tctgtcatct atgcttctcc aatcaaacgg agcagatact gtccgtattc
     3061 atttttctta agtggttggg ctaaggccaa tacatcttct cgactgatat agcccatacg
     3121 gtaagcaatt tcttctaagt ttgctacctg aacattttgc atccgttgca ctgtttcgat
     3181 gtactgtgaa gcctctagta aactttcatg agttccagta ttcagccaag caaagccacg
     3241 tcccataagc tcaacagaca aatcaccacg atctaggtaa gccttgttta catctgtaat
     3301 ttccagttca ccacgagggc ttggtttaat actcttggca atttcgacaa catcgttatc
     3361 atagaaatac agtcctgtca ctgcatagtt ggagcgagga tactccggtt tttcttctat
     3421 ggaaatagca ttcatgtctg tatcaaactc aaccacacca aaacgctctg gatccttcac
     3481 ttggtagcca aaaacagtcg cacctttctc tttcttggct gctttttgaa gcattgtgct
     3541 cagaccagga ccatggtaga tattgtcgcc taaaatcaag gcaacgctat cgtcagaaat
     3601 aaactcttcc ccaattgcca aaccatctgt acttggttgc tctgcataag aaagtttgat
     3661 cccaaactca gatccgtctt gaagaagctc ttgaaatcga tgtaaatcct gtggagtgga
     3721 aataatcaaa atatccctaa tcccagccaa catcaatgtt gaaagtgggt agtaaatcat
     3781 cggtttatca taaaccggca taagttgttt tgacgcagcg cgagtcaaag gatataaacg
     3841 tgtccccgaa ccacctgcta gaataatacc tttcatagta gggtaccttt ctttgttatt
     3901 ttagagtcaa ttactattaa ttgtgtactg ctctaaaaag aaaacaatca tcccatgttt
     3961 tatatggctc tataatattt gtagtgggta aatccactat agatattatg gagcctattt
     4021 tattgtagaa aaaaagtccc ataagatcta taatgaaaag cgaccaaaca actcattaga
     4081 aagattcata tgggacaatt acattttatc acaaaactac tcga
//
LOCUS       DAVAZV010000092         4116 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVAZV010000092 DAVAZV010000000
VERSION     DAVAZV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4116
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.092"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..776
                     /locus_tag="VQT46_002060"
     CDS             <1..776
                     /locus_tag="VQT46_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000603792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372013.1"
                     /translation="DYSIVEEKLDWQSKLSKIYPNVEFIKIEKLKLILLCKYRNQIID
                     LEDDKKRLLLLKLLYLTSKQFCYDEFKGAKFGCMSFFSHYQGYMSRLDSLDSDKFVSV
                     KQRIVSSISKLVEQYSDHIINLDRTLVDSLSDTLENQLFDDWDYILSEITTYSELLAK
                     SGLLYNSLDYKIDNVKKEVAKLSDFHQSLFKIEGFSDFFDSWQFQRYRSLVNQVYEIF
                     SMLQVSSVERTVLCGALSTIVFSKSNFNYQAFFEYLKDT"
     gene            805..1713
                     /locus_tag="VQT46_002061"
     CDS             805..1713
                     /locus_tag="VQT46_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372014.1"
                     /translation="MDYVDVILDEYGSVFLIKDHIKLKINNLELYRYFSSFGMSHLQF
                     RKEELPGKLKQFDFEKNKSDSYFSKKSSLIDFIKRNYFYDIKLYSDNPKNPIESWKNK
                     TEKIKIAKSTEILWSEVANFSSISKSPYYCLLYNLKNTENYILIISKTYFSAIQKMVS
                     YNLNNYFELEDVCCKSIVSKRELIENSININKSKMKLLNVCEGSKGYTRRVFKYNNIF
                     VGQLEFHSNIIFSEIALNELSIVKLLDSVESVLSEQLFGKLNWDNLFVVLSDDFNDYL
                     DINESQKYYSNGSLRGLELGIFMGGV"
     gene            1715..3613
                     /locus_tag="VQT46_002062"
     CDS             1715..3613
                     /locus_tag="VQT46_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HET2372015.1"
                     /translation="MRIIEIVDVEDQLLQLLSAHTNIDIRAQELSTLDPDSKVDLIIY
                     LKSRRDIENINNIIIKSPNRNIIVIISAFDIIYALYFPKSTFRPCLNCLLLKLKDNNP
                     EHNLLLFLKYGTLPSKHFNLDNRLKSNLILFNEKLDPKVEEYSIEGVNTTNFTFHFSC
                     SCENSGYDMSERMADILLGEGKKLSPKNYRLKKSEHLFDFTRYLDRNFGFFHHSYDEK
                     ISEYAPLHAVEINVDAGYESGWGRTFMTEAATKSAFLESLERYCNSRNRRYKKLIRGC
                     FSDLSKKYNTLNPVDFCLSNKEYRDSSYKFHDFDSEKNYDWIFGKNITTGKICLLPSQ
                     LVFYKDFSKSEENERFVYETSNGCALGSSIEEAIFYGILEIIERDNFLLTWYLKEEVK
                     QLSWESLPSRLRIINERLKEDNCELKLFNITKEVGIPVIWALYINHNENASIRSFSAA
                     GCHINPLSAIESAIFEVITSVPTFERLIEVRNKESFIEEIQNNFSLIRDIDDHILYHA
                     HADYKNKMPFLFKNNYSEYQNEFDENRIFNTYSHATLTSDLQALIKIIEKKFGDIYVV
                     NISDKVSEKFGLYCVKVLIPGLLNMSFGHSNRRVNIERIKNYVDYRGGNVNSITLNSI
                     NHLPHPFP"
     gene            3637..>4116
                     /locus_tag="VQT46_002063"
     CDS             3637..>4116
                     /locus_tag="VQT46_002063"
                     /inference="COORDINATES: protein motif:HMM:NF025394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="HET2372016.1"
                     /translation="MKRDWKSKHLFYHDVQQFDKLVIYLSKFMDKLVNQNQIEKYFYI
                     RYWEGGPHIRLRYLVRDTQNFETIDSMINKYAYKFWENNPPMKLLNKTDYKKIYNESI
                     DNNGKMDRKLRKNATIENIAYIPEIERYGGEEALIVSEDLFCICSQVSTALLNVVDNY
                     "
BASE COUNT         1539 a          443 c          712 g         1422 t
ORIGIN      
        1 cagattactc aatagtggaa gaaaaattag attggcaaag taaattatct aaaatttatc
       61 cgaatgttga atttataaaa attgaaaaat taaaattgat tttgttgtgt aaatatagaa
      121 atcaaattat tgacttagag gatgataaaa aaagattgtt actattgaaa ttattatatt
      181 tgacttcaaa gcaattttgc tatgatgaat ttaaaggagc gaaatttgga tgtatgtcat
      241 ttttttcaca ttatcaaggt tatatgagca gattagattc actcgactca gataaatttg
      301 tttcggttaa acagaggatt gtttcctcta tttctaaatt agttgagcaa tattcagatc
      361 atattataaa tctggataga actttagttg attctctaag tgataccctt gagaatcagc
      421 tatttgatga ttgggattat atattaagcg aaataactac atatagcgaa ttattagcaa
      481 aatcaggatt gttatataat tcgctagact ataagattga taatgtaaaa aaagaagtgg
      541 ccaagctaag tgactttcac caatctttat ttaaaattga aggattttca gatttttttg
      601 atagttggca atttcaaaga tataggtctc tcgtgaacca agtttatgaa attttttcaa
      661 tgttacaagt aagtagtgta gaaagaactg tgttgtgcgg agctctaagt actattgtct
      721 ttagtaagtc aaattttaac tatcaagctt tttttgagta tctaaaagat acgtagaatt
      781 cgattttaaa ggaggctgaa atatatggat tatgtagatg taatattgga tgagtatggg
      841 agtgtttttc tgataaagga tcacataaaa ctaaaaatta ataatctaga actatatcgg
      901 tattttagta gctttggaat gagtcatctt caatttagaa aagaagagct tccaggaaaa
      961 ttaaagcagt ttgattttga aaaaaataaa agtgacagtt atttttctaa gaaaagtagt
     1021 ctgattgatt ttattaagag aaattatttt tatgatatta agttatattc tgataatccg
     1081 aaaaatccga tagagtcttg gaaaaataag acagaaaaaa ttaagattgc taaaagtaca
     1141 gaaattcttt ggagtgaagt agcaaatttt tcgtcaattt ctaaatctcc ttactattgc
     1201 ttgttatata atttaaagaa tactgaaaat tacatattga taatcagtaa gacatatttt
     1261 tcagccatcc aaaaaatggt ttcgtataat ctaaataatt attttgaatt agaagatgtt
     1321 tgttgtaaaa gcatagtgag caagcgagaa ttgatagaaa attcaattaa tattaacaaa
     1381 agcaaaatga aactgctaaa tgtttgcgaa ggtagtaaag gttacacaag aagagtattt
     1441 aagtacaata atatttttgt gggacaattg gaatttcact ctaacataat cttttcagaa
     1501 attgctttaa atgaattaag tattgttaag cttttagatt ctgttgaaag tgttttatct
     1561 gagcaactat ttggaaaatt aaattgggat aatttatttg ttgttttatc agatgatttt
     1621 aatgattatc tggatataaa tgaatctcaa aaatactact caaatggttc tttgagagga
     1681 ctggagcttg gaatctttat gggaggggtt taaaatgaga ataattgaaa ttgttgatgt
     1741 tgaggaccaa cttttacaac ttttaagtgc acataccaat attgatatta gagcacaaga
     1801 gttatcaaca cttgacccag attcaaaagt tgatttgatc atatacttga aatctcgacg
     1861 tgatattgaa aacataaata atattattat taaatcacct aacaggaata tcattgttat
     1921 aataagtgct tttgatatta tatatgcatt gtattttcca aaatcaacat ttagaccttg
     1981 tttgaactgt ctattattaa aacttaaaga taacaaccct gagcataatc tattattatt
     2041 cctgaaatac ggaacattac ctagtaaaca ttttaatctt gataataggt taaaatcaaa
     2101 tttaatacta tttaatgaga agttagaccc taaggtagag gagtatagta ttgagggggt
     2161 aaatactaca aattttactt tccattttag ttgtagctgt gaaaatagtg gttacgatat
     2221 gtcggaaaga atggcagata ttctacttgg tgaaggaaaa aaattatctc ctaaaaatta
     2281 tcgtttaaaa aagagtgagc atctattcga ttttactaga tatctagata gaaattttgg
     2341 attttttcat cattcatatg atgaaaaaat ctccgaatat gcgcctctcc atgcagtaga
     2401 gattaatgtt gatgctggtt acgagtcagg ctggggaagg acttttatga cagaggctgc
     2461 aacaaaatct gcttttttag agtcattaga gagatactgc aactctagaa atagacgcta
     2521 taaaaaatta attagagggt gtttttctga tttatctaaa aagtacaata cattaaatcc
     2581 tgttgatttt tgtctttcta ataaagaata tagagatagt tcctataaat ttcatgattt
     2641 tgattctgag aaaaattatg attggatatt tggtaaaaat ataactaccg gaaaaatttg
     2701 cttattgccc tcgcaactag tattttataa agactttagt aaaagcgaag aaaatgaaag
     2761 gtttgtttat gaaacatcaa atggatgtgc tttggggagt agtattgagg aagctatttt
     2821 ttatgggatt ttagagatta ttgaaagaga taatttttta cttacatggt atttaaaaga
     2881 agaagtaaaa caattatcat gggaatcttt accatctcgc ctacgtatta ttaatgaaag
     2941 actaaaagaa gataactgtg agctcaaact ttttaatata actaaagaag tgggcatacc
     3001 agtaatttgg gcattgtata taaatcataa tgaaaatgct agtattcgaa gtttttcagc
     3061 tgcaggctgt catattaatc ctttaagtgc aattgaatca gcaatttttg aagtaataac
     3121 ttctgtgcca acttttgaaa gattaattga agttagaaat aaagagtcat ttattgagga
     3181 aattcagaat aatttttctt taatacgaga tattgacgat catatattgt atcatgctca
     3241 tgcggattat aaaaataaaa tgcccttttt atttaaaaat aattatagtg aatatcaaaa
     3301 tgaatttgat gagaatagaa tttttaatac ttattcacat gcaacgctta catcagattt
     3361 acaggcacta ataaaaatta ttgaaaaaaa atttggagat atatatgtag tgaatataag
     3421 tgataaagtt tccgaaaaat ttggacttta ttgtgttaaa gtgttgattc ctggacttct
     3481 taatatgtca tttggacatt caaatcggcg tgtaaatata gagaggataa aaaattatgt
     3541 agattataga gggggaaatg taaatagtat tacattgaat tccataaacc atcttcccca
     3601 tccatttcca taagattata tataaaggaa taataaatga aaagagattg gaaatcaaag
     3661 catttatttt atcatgatgt tcaacaattt gataaattgg taatctattt atcaaaattt
     3721 atggataaat tagttaatca gaatcagatt gaaaaatatt tctatattcg ttattgggaa
     3781 ggggggcctc atattcgatt aagatatttg gtgagggata cacaaaattt tgaaacaatt
     3841 gatagtatga taaataagta tgcttataaa ttttgggaaa ataatcctcc aatgaagtta
     3901 ttaaataaga ccgattataa gaaaatttat aatgagagta ttgataacaa cggaaagatg
     3961 gatagaaaat tgaggaaaaa tgcgactatt gaaaacattg cctatatacc ggaaatagag
     4021 agatatggcg gggaagaagc tctgatagta agcgaagatc tattttgtat ctgtagtcag
     4081 gtttcaactg cgttacttaa tgtggtagat aactat
//
LOCUS       DAVAZV010000093         3309 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVAZV010000093 DAVAZV010000000
VERSION     DAVAZV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3309
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.093"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            260..849
                     /locus_tag="VQT46_002064"
                     /pseudo
     CDS             260..849
                     /locus_tag="VQT46_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(815..2290)
                     /locus_tag="VQT46_002065"
     CDS             complement(815..2290)
                     /locus_tag="VQT46_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET2372017.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDDSVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            2997..>3309
                     /locus_tag="VQT46_002066"
     CDS             2997..>3309
                     /locus_tag="VQT46_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2372018.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTKIKRRTVRKCLGKGRFKEVYSADYAQQSYENNRKHSVKRSSVTKELKEKILHYHNQ
                     KF"
BASE COUNT         1040 a          715 c          590 g          964 t
ORIGIN      
        1 tctaaccaca gctttttgtt tcaattggta atgagtttga taacgcatag acgttttatc
       61 tcgtctaagg taacaaggca aaaagttcgt ggataaccaa gtagacttga aatactatat
      121 ctggaggtac tcccatgctt tatgtgggca ttgatgtcgc taaaaataaa cacgatgtta
      181 cagccttgaa tgttcgagga aaactgttct taaaccactc actttttcaa ataataaagc
      241 tggttttgaa ctcttagatc tgtctcttcg acaactcaac caagactgtc tcatcgctct
      301 tgaaaatacc ggacattatg cctttaatct actgaacttc ctgcatgaac aaggatataa
      361 agtttacacc tacactcctt tgctcatcaa ggaatttgcc aaatcattat cacttcgcaa
      421 gactaaaacg gataagaaag acgctcatgg catcgctctt aaacttcttt ctgaccccaa
      481 tcgtgaacaa tttcaacacg ataatcggca agtagaacta aaaatactga ctagacatat
      541 tcatcgtctc aagaaaaaac agtctgattg gaaagtacaa tacactcgtt gtcttgatat
      601 catctttcct gagttggata aaatcgttgg aaagcattca gaatatacct accaactctt
      661 gacacgctac cctaatcctc agaaaaggat tgaggcagga tttgataagc tgatagaaat
      721 taagcgattg accgcttcta attcaagggc tttttgccgt gctctaaaat catcgccaaa
      781 tcatcaaatt gaaataagaa atagtttaga taaactattg acttttctta tagtttgtct
      841 ttctcttaat aacgttgata tgattgacct ctggatcttc cgtcccttgg agggagcaac
      901 cacgttcctt ggcgaattgg atatagtcga caatttctcg tgtaatgcgt tcaccaggag
      961 ccaagatagg aatacctgga gggtaacaca taacaaattc tccacagacc tgtccaacag
     1021 aatcatccaa agttaaactt tttctttctg aatagaaggc ttcttgcgga gacagcacta
     1081 actcgggctg aatatattct cctgctatca aatcttttcc atctcttgaa tagagtctct
     1141 taatatcagc cagagcacca accaagcgct cgatgtcttg gatgcggtcg ccgatggaaa
     1201 tataggccaa gatattgccg atatcaccaa actcgatctg aatgtcgtat tcgtctcgca
     1261 agaggtcata aacctcgata cctgttaagc caataccctg agtgtaaact gacaacttag
     1321 ttacgtcaaa atcgcaaacc gaaacaccgt ctattaactc ttttgagtag gcatagtagc
     1381 caccgatagc attgatttca tgacgagcgt actcggatag ctcaatgact tcctcaaacg
     1441 actctttacc acgaagggcc aagttgcgac gtgaaatatc caaactagcc atcaataagt
     1501 aagaggcaga tgtagactgg gtcaggttta taatctgacg aacgtactcg ggattcatct
     1561 gctccccgat taaaagaagc gaactttgtg tcaaactccc accagactta tgcatggaaa
     1621 ctgctgccat atcagctcct gcatccatag cagaaattgg aagtttacca gtgaaatgca
     1681 aatgcgctcc atgggcttca tctactaaaa ccatcatgcc agcttcatga gccatttctg
     1741 tcaacccctt taggtctgaa cagatgccgt agtaagtagg attgttgatt aggatagcct
     1801 tagcatctgg atggtccttt atggcctgtg ctactcggtc attttcaaga cctaaagcga
     1861 taccaatctt aggatctaca ctcatctcga tatagatggg aatggcacca catagaacca
     1921 acgcattgat agcagattta tggacatttc gtggcagaat aatcttatct cctgccttgc
     1981 aggttgccag aatcatagtc tgcaccgatg aagttgttcc accaatcatt agaaaggcat
     2041 ggctagctcc aaaagcatct gcagccagct cctctgcatc acgaataatc gaaataggat
     2101 ggcctaaatt atccaagggt ttcatcgaat tgacatcaat gcctacacat ttttctccta
     2161 agagttcgac aagttctgga tttccccgtc cacgcttgtg acctggaaca tcaaagggaa
     2221 caatcctttt cttgcgtaac ttcaccaagg cctcataaat tggggcttgg ttttgatcta
     2281 actctttcaa aacatactcc tttcaatatt tttaggacct tatgaaaact aaggaactaa
     2341 aggttgactc atgaaaaaag agcaggtttt cacctgctct gcaatcttct gacgtgttta
     2401 ttttggtttc tgttgagtat gtctgttccc gatgtttcct aactctctag tagcaaatat
     2461 tacgtacttt attgatcgtt tcacaagatg acgtgtgctt tcaccacact aaaaatttat
     2521 gaattaggac aagtgtccta acatcaactt ataaaagtag gcttttaacc ctatcaataa
     2581 tgtggctttt caaccacgct tcggcattca accctgcctg tccgtaggca ttttttactc
     2641 gggtttatat ttgctagaaa acatcatctc attttctaag ctttattact atatcatgtt
     2701 tttaagaact tgtaaagtat tttttgataa aaaacaaaaa tataatagat tgaaactaga
     2761 atagtacacc tctgcttcta aaacattgtt agaaatagat tttactgtcc tgatcgattt
     2821 gttctgttct tgtttcattt tactatatgt tcgtaaatga aagttctata atgaagttag
     2881 ccacccagcc ctcctaaaaa ttagatggtt caactagctg atagctcttg taggcataag
     2941 aaaacacctc tgtgttatac ttgttgttca accacaaaca caagaaaggc acagaaatgc
     3001 aagacaatta tactacaaaa ggtaaacatt tgacaatcga tagccgtcgc ttaatcgaaa
     3061 gatggaaaaa agaaggaaaa tcaaatagag aaattgcctc tctacttgga aaagctcctc
     3121 aaactatcca cactaaaatc aagcgtagga cagtccgaaa atgtcttgga aaagggcgct
     3181 tcaaagaggt ttattctgcc gactatgctc aacagtctta tgaaaataat cgcaagcact
     3241 cggtcaagag atcaagcgtg accaaggaac taaaggaaaa gattctccac tatcataacc
     3301 aaaaatttt
//
LOCUS       DAVAZV010000094         3262 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVAZV010000094 DAVAZV010000000
VERSION     DAVAZV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3262
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.094"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQT46_002067"
     CDS             complement(216..827)
                     /gene="rpsD"
                     /locus_tag="VQT46_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET2372019.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1022..2074)
                     /locus_tag="VQT46_002068"
     CDS             complement(1022..2074)
                     /locus_tag="VQT46_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET2372020.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVTKLEKGQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2071..2769)
                     /locus_tag="VQT46_002069"
     CDS             complement(2071..2769)
                     /locus_tag="VQT46_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET2372021.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2936..>3262)
                     /locus_tag="VQT46_002070"
     CDS             complement(2936..>3262)
                     /locus_tag="VQT46_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET2372022.1"
                     /translation="VKETSDTANGSLSPSNSGSGVTPMNHNHATGTTDSMPADTMTSS
                     TNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLALAGLLGGLGLK
                     NKKEEN"
BASE COUNT          912 a          735 c          626 g          989 t
ORIGIN      
        1 ttttttacga aaatctattg aatatgccat aaaaggatta taccacattg tgtactattt
       61 ttggttcatt ttactatatc actttggact atatcggtct agttatgtct aaacgattat
      121 agctggatac taagagaaat caaaaaagca ctaagggaga acgtcccaaa gtgcttaata
      181 tcaaggcctc aaagcctgtc ttattcaata aaatattaca acatcttgtt gtagaattca
      241 acgacaagtg cttcgttgat ttctgggttg atttcgtcgc gttctggcaa gcgagtcaat
      301 gaaccttcca atttttcagc gtcgaatgat acgaatgctg gacgtccaag agtagcttct
      361 actgcttcaa ggattgctgg aactttcaat gatttttcac gaactgagat cacttgacct
      421 ggagttacgc ggtatgatgg gatatcaacg cgtttcccgt caacaaggat gtgaccgtgg
      481 tttacgaatt gacgagcttg acgacgagta gtcgcgagac caagacggta aacaacgtta
      541 tccaaacgac gttccaaaag aagcataaag ttgaaaccta ggattccgcc tttgattttt
      601 gtagcttgta cgaacaagtt acggaattgt ttttcaccta caccgtaagt gaaacgaagt
      661 ttttgttttt cagccaattg caaaccgtat tctgacaatt tagaacggtt gtttggtccg
      721 tgttgtcctg gtacgtagtt acgacgtgcc aattctttac ctgtacctgt aagtgaaagg
      781 ccaaggcgac gagcttgttt ccaagatggt cctgtataac gtgacatatg aatgtcctcc
      841 tgatataaat aatatttcgg tggaaatagt cacttagaaa gccctgattc gtgcagatgc
      901 ccttcgccta aacagccaag gttacttgtc ataagacacc tgttgacgag cttcatgctt
      961 tcctgctgat atttcacaca aaatccattt taccatgaat agctggattt gtaaaggggt
     1021 tttaggcttt attttcacta ccagagagat tgagaacgag ggtaaaggta cttcctagac
     1081 cgtactggct gctgactgtg atttccccac ccaattgatg ggccaattca cgcgcaatcg
     1141 caagtcctaa tccatgacca cctgtcttca tgttacgcga agtttcgaca cgataaaggc
     1201 gtttgaaaat attttccaaa tcctctgggg caatgccctg cccttcatcg gtcacactga
     1261 ttgaaagctg gcccttctcc agcttagtca ccacttccag cttggttcct ggagcagaat
     1321 atttaaaagc gttatcgacc agattcacca agatacgaga aagcttagca taatctccct
     1381 caatccgggc agactctggg attacctgca agtggacatc tcttctctcc tgctcaatca
     1441 aaaactgaaa ttcactcatg cactcaatta agagcttgtc cagaaaaata ctgtctttac
     1501 tggtagtttc cacctgattt ctagctgtgt ttagggtcaa aaaattcaac tcctcaacca
     1561 gtttattgag cctctccgtc tggcgtccaa tggttgctag ataatgagct tgctccgact
     1621 ccttgataat cccatccaaa atcccttcta ccgtcgcttg gatcgaagtg ataggggtct
     1681 taatatcatg cgacaactgg gcaatcatca agcccttttc tcgttcgctt tcttccaagg
     1741 aatcaaagct tacctgcaaa tcatgggaca tctcattaaa agtttgccct aattgctgaa
     1801 attctacagg accttgaacc tccaaatttg aaggaaaatc cttggccgct acccgcttgg
     1861 catgctcctt gagtttgccc aacgacgtaa agactggcaa taggagaaag agactaatcc
     1921 cagcaccgac aaggctggca acgatggtca tcccaagcaa aaagtaaatc tcgcctttcg
     1981 caatcagcat tttttgaaca gcccaaaaaa caaccaaaat ggttaagagg gttgaaataa
     2041 tatatccaac caaaatataa ctttttagtt tcatgtttgt cctctcggtt tctctatctt
     2101 atatcccaac ccccaaactg tcttaatagt gggcgtttgg tcactactat attttgccag
     2161 ctcctgtcga agagcatgga tatgcacatt caaggtattg gtgtcatcca cgtagtcttc
     2221 tttccagatc ttttcataga ggtctgtctt ggagaaaact cgctctggat tgctagctaa
     2281 aatccacagc aattcaaatg atttaacagt taaatccagc atttcttctc ctatttgaac
     2341 ttcatgacta ctatgattca tttttagatt gccaagggaa atcagctctg tttcgccccc
     2401 acgatgaagg cggcgcaaaa tattgtggac acgcaaaacc agctcacgtg ggctaaaagg
     2461 cttagcaata aaatcatctg ctcccaagct caggccgtaa atcttgtcct gttcactggt
     2521 cttagcagta ataaatagga aaggctgctc tggtgataag tattgaacct cactgattaa
     2581 atcataacca tccatccgag gcatcataac atctgtgata atcaaatcaa tcggtttttt
     2641 cttgaacagc tctagcgctt ccagtccatc atgggctacc aagacctgat aacctgcctg
     2701 aattaagtat ctctgatgaa tatctgtgat ttctacctcg tcgtcaacga gtaaaattgt
     2761 ctttcccatc tgtctctcct ttgataaaaa cagtgctata ctgctttaag tataacacta
     2821 tttttattgt tttacgatga ttttaatctg ctattgaaag aaagtcctga ttgctgattg
     2881 agttgttaaa ctaatcttag tcagcccact atccatcatt tatttcctta gctgattagt
     2941 tttcttcttt tttgtttttc aaacctagac caccgagtaa acctgcaagc gcaagcccaa
     3001 ggaaaccaat acttgccatt gatgtttgag tctcaccagt atttggtagc atagctttat
     3061 cctctgacat catcgtatca gacatcttgt tagcagaagc agccatgttt tcacctgcca
     3121 tcgtgttggt agaacttgtc atggtgtcag caggcatgct atctgtagta cctgtagcat
     3181 gattgtgatt catcggagtc acgccagaac cagagttaga aggtgataat gaaccatttg
     3241 ctgtgtctga tgtttcttta ac
//
LOCUS       DAVAZV010000095         2987 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVAZV010000095 DAVAZV010000000
VERSION     DAVAZV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2987
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.095"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..2288)
                     /locus_tag="VQT46_002071"
     CDS             complement(<1..2288)
                     /locus_tag="VQT46_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec-dependent serine-rich glycoprotein
                     adhesin"
                     /protein_id="HET2372023.1"
                     /translation="MFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVIS
                     GTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTS
                     ASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKP
                     ASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIA
                     KSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHG
                     YSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNG
                     AQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTT
                     SQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSA
                     SASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASA
                     STSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESAST
                     SASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSA
                     SASASTSASASASTSASESASTSASASASTSASASSSTSASASASTSASASASTSASA
                     SASTSASASASTSASESASTSAS"
     gene            complement(2286..2399)
                     /locus_tag="VQT46_002072"
                     /pseudo
     CDS             complement(2286..2399)
                     /locus_tag="VQT46_002072"
                     /inference="COORDINATES: protein motif:HMM:TIGR03715.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
     gene            complement(2637..>2987)
                     /locus_tag="VQT46_002073"
     CDS             complement(2637..>2987)
                     /locus_tag="VQT46_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2372024.1"
                     /translation="AFLREIAARFDCALPSVWAVLKQIKVILKKTTSFREQKPEKVSE
                     FLDILDNLKDLPVLYIDETGINRYLYRPYAGAPRGEKVYDKISGRRFERTNEVEQKLN
                     GSFLIRYIDSQIRE"
BASE COUNT          761 a          639 c          708 g          879 t
ORIGIN      
        1 gacgcactcg ttgaggctga ctcagacgca ctcgttgagg ctgaagctga cgcactcgtt
       61 gatgctgaag ccgaggcact ggttgacgct gaagctgagg cgcttgttga tgctgaggct
      121 gatgcgcttg tgcttgatga agctgaggca cttgttgatg ctgaggctga cgcactcgtt
      181 gatgcagatt cagacgcact tgtgcttgct gaggctgacg cactggttga tgcggaagct
      241 gaggcgcttg tgcttgctga agccgacgca ctcgttgagg ctgaagctga agcgcttgtc
      301 gatgctgagg ctgacgcact tgtcgacgct gaagctgaag cactggttga cgctgaagct
      361 gaggcactgg ttgacgctga agctgacgcg ctggttgagg ctgaggctga ggcgctagta
      421 cttgctgact ctgatgcact ggtacttgct gaggctgacg cacttgtgct tgctgaagcg
      481 gacgcactcg ttgatgctga agctgaagca ctggtacttg ctgactctga tgcactggta
      541 cttgctgagg ctgacgcact tgtgcttgct gaagccgatg cactcgttga tgcggaagct
      601 gatgcacttg ttgatgcgga agctgatgca ctcgttgatg ctgaagctga ggcgctagta
      661 cttgctgagg ctgaggcact ggttgatgcc gattcagatg cactggttga ggccgattca
      721 gacgctgagg tacttgctga agctgacgca ctggttgacg ctgaagctga tgcactggtt
      781 gacgctgagg ccgaagcact ggtacttgct gaagccgacg cactggtgct tgctgaagcc
      841 gaggcgctag tgcttgctga agccgacgca ctcgttgatg cggaagctga cgcactcgtt
      901 gatgcagatt cagacgctga ggtacttgct gaagctgagg cactcgttga tgcggaagct
      961 gacgcactcg ttgatgctga ggctgaggca cttgtacttg ctgaggctga tgcgctggtt
     1021 gaggccgatt cagaagctga ggtgcttgct gaggctgagg cgctttgact agcacttact
     1081 gagagtgact tagactgtga aagtgactga ctggtcgtgc tagattcaac tacctttcct
     1141 ctacccttga agtagttagt tctaatgtta tctgttttag cagcgtaagg ggtaaatgta
     1201 aaggatgtat ccgttccagt aattggtaca gtccaagatg atgttaatcc atatccttgc
     1261 ttagcaaaga aaccattcat ttgggcacca tttccccaag tatacccact accccacgtc
     1321 gtcattgtag atgtattata ggatcgaacc agtacaccat ctttgtcagt aatgtagttc
     1381 tttacatctg aaggggtacc aagatcactg ccaagggtta acattgtttg tattgaagta
     1441 cctgtattat agatagaata cccatgaccc atctttgaaa gattaccaag agcccttgtg
     1501 gtaggatcta catacgtaac cgtataggta aaggtcagtt ttgaaccatc atttgtcact
     1561 gtcaatttat agtaaattgg aacatgatat accgaatcta aacctgtacc tgtataaact
     1621 tttgtctcac ttttagcaat gtttagactt gcattaattg caggggcgcc atttacaatc
     1681 gtattgccag aaaaaacagc agcttttata gaagccagca attgctcgat ggaatccact
     1741 gaacgcttgc gtcgcttagc ataagattgg agattgacat ttgtaactga tgctgcataa
     1801 tcactagctg gtttcttacg atcttcttcg accttcttag cagttgcttc tgtagcggca
     1861 gctgtttgtg atcctaccac agtagatgat gcagagatac ttgtcgaagc cgatgtactt
     1921 gctgattctg atgcacttgt actcgctgag gtcgaagcgc tggttgaggc tgactcagat
     1981 gcagatgtac ttgccgactc tgaagctgac aaactagttg aactcgctga attacttgta
     2041 gatatcgtac ctagaactac tgtatcattt gttgccaaag catccgtttt ctctacagtt
     2101 ttttcaagta ctgccgactc atttgtaaat accttcgttt gagttgcaac ggttccactt
     2161 atgacagttc ccgcagcaac tattcccttg aggatatcaa gcccagtaat tgaatgactt
     2221 actttatctt ctaccgtttc ggtcatgacc tgagtagtat caacaccacc acgcatgacc
     2281 ttaaacaagc caaaaagaga agtcgaggcc cgtagccaat gcttccctga tttgattaat
     2341 ttgaaccgag ttactcggtc tgtttctcta tattcaccct tctgacgtct aaaaaatatt
     2401 ttgaaatttc ctttcgagta ttattttcat gtatggatat aaataaatta ccatactata
     2461 attatagaat agggaaccca aaatagcaag aaacttgagg tatttttgct aaaaaaaaaa
     2521 agcattttac tattttatat atatattata agataagttt tttataaaga cacgcaaatg
     2581 agtataaatc agctaatttt tggtttatat tcctattttt atgcataatt attctttcat
     2641 tctctaattt gtgaatcaat atatctgatt agaaaactac cattgagttt ttgctccacc
     2701 tcattagtcc gctcaaaacg ccgtccgcta atcttgtcat agactttctc ccctctagga
     2761 gcccctgcat aaggacgata gaggtagcgg ttgattcccg tttcgtcaat atataggact
     2821 ggtaaatctt ttaggttatc caaaatatca agaaactcag aaactttctc aggcttttgt
     2881 tccctaaaac tggtcgtctt ttttaaaatg accttaatct gctttaaaac tgcccatacg
     2941 gagggcaaag cacaatcaaa acgggccgca atttcccgta aaaaagc
//
LOCUS       DAVAZV010000096         2694 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVAZV010000096 DAVAZV010000000
VERSION     DAVAZV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2694
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.096"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            276..590
                     /locus_tag="VQT46_002074"
     CDS             276..590
                     /locus_tag="VQT46_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372025.1"
                     /translation="MWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRRVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            600..806
                     /locus_tag="VQT46_002075"
     CDS             600..806
                     /locus_tag="VQT46_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET2372026.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            806..1003
                     /locus_tag="VQT46_002076"
     CDS             806..1003
                     /locus_tag="VQT46_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372027.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            1059..1739
                     /locus_tag="VQT46_002077"
     CDS             1059..1739
                     /locus_tag="VQT46_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET2372028.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVVIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1751..2392
                     /locus_tag="VQT46_002078"
     CDS             1751..2392
                     /locus_tag="VQT46_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET2372029.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            2410..2640
                     /locus_tag="VQT46_002079"
     CDS             2410..2640
                     /locus_tag="VQT46_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372030.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          791 a          441 c          559 g          903 t
ORIGIN      
        1 gatagaactg acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa
       61 gtcagtaacc atacctacgg caaggtgaag ctgacgtggt ttgaagagat tttagaagag
      121 tattaatgat agataaagtg gtcaggaacc tactcctgac ctttttcttt tgcaaaatga
      181 caaaaatcat aatttttttg acaactatac ttgtcaaaaa gaaaaagatg tgttacaatg
      241 taagcaagtt aagagaaaag aagaaaggag ctatgatgtg ggtactaggg tttatactat
      301 ttctgatttt cttttattct aatgattcta aaaaaatcaa gaaactagag aagaaaatca
      361 aaagacttga gcgaaaagag aaaggaaatg cagaaatgtc gagattatta caagaaatga
      421 ttggaaagga accaattata acgggagtgt atattgggcc agataactgg gaagttgtgg
      481 atgttgatga ggaatgggta aagctacgac gtgtagataa tacgggaaaa gaaaaattca
      541 agttgcaacg tattgaggat atccaaaccg ttgaatttga cggagagtag gtgtgtaaca
      601 tgcaactaaa aaatcgtcta aaagagcttc gagctcgcga tggtctcaat caaaccgacc
      661 tagccaaact ggcaggggtt tccagacaga ccattagcct actagaacgg gatgagtaca
      721 ccccatccat tatcattgcc ctgaaaatat ctcaaatttt caacgaaaca gtcgaatcgg
      781 tatttcgttt ggaggaggac gagtgatgaa caagtataaa gtgatttatt atgtagtggt
      841 catagcttta ttagtcagcg tatttctact gattgggatg gacctaagct ggtttaatcc
      901 ctatcaaagc gaccaatttg tttgggtcta ctttgctctc atcccagtaa ttgaatggat
      961 tgaaaagaaa tccaaaaatc tagcaagtga aaaaggagaa tgaatatgaa aaagaaacgt
     1021 agattgttat ttttgatgtc tattgtcttg gggggttctt gggcatgttt gtagggatgt
     1081 ttaaggcacg tgtcgaatcc cacgaaatta ttttagatgt aaaagccttg atgccatgga
     1141 tatcagctat ttgtttactg ataggtttca ttagtatgtt tttgactttc aatttcttaa
     1201 agaaaagcag aaaatttcat tccttgtatc aagaggaaat ggatgacgat ctgaatgaaa
     1261 cctattatgt gcaaatgtat cggaatcttg agtttggaac cattgctttt aatattacag
     1321 gtgtagtgat tccattggct atttttattt cattaagtga ggtgattata ttgcatacaa
     1381 accctcaaac atttttcctt tctttcttac tctttgtggt attcttagtc gctcaaaaat
     1441 ctctttttaa aaccattgcg attgttcgtc agtttgattt ggaatttttc gctacaccaa
     1501 aggatgtctt gaactatata aattcttatg atgaagggga gcgtcaggct aatttggaac
     1561 agagttttcg aattttattc caattacacc aatatgtctt accagcctta tatatttttc
     1621 ttattatcct ttctttcttg acaggagaga ttcagttact agctttcttg cttgtaggag
     1681 ccattcatgt ttatatcaat gtgatgcagt tacctatggt aaaacgttat ttcaaataaa
     1741 ggagttatct atgaaattac ttaaaaacct tggctggttt cttctagccc ttctatcctt
     1801 tttctttatc tatggcttta ttcaggggct cgcgactgcg tcgcttgctt taggcgcttc
     1861 accctatgct gttactctac tctatgtggt cttggctgga gtatatgtgt acggcattta
     1921 caaatggtat cagaaagctc ctgtttatat tgagaagagc ggctttaacc gatttatttg
     1981 gcttcctgcc ttggtttggt tcttatctct ggtcgttcaa ttcttcttgc cagatgatcc
     2041 ttcagtaaat cagcaaatag cgacagactt gaccttgtct caaccacttt tctcattctt
     2101 tgctgtggtt atttttgctc ctttgacgga agagattgtt tttagaggga tgttagcacg
     2161 ctatctcttt cctaagcagg acaatagtaa acgaaccctg atttttcttc tggtatctag
     2221 tcttctattt gccttgattc attttccagg tgatgtgcaa caattttttg tctattttag
     2281 ccttggtttt agtttgggtt tggcttacat tagcagaaaa ggtctggtct acagtatttc
     2341 tcttcacgct ttgaataatt tagtcggctt tttgatgatt ctcatgctat aatagagtca
     2401 ggaggtcaca tgaaacgagt aattttatta gcagtgattc aggcagtcgt tctatttttc
     2461 atcattggag cgctagctta tgccttcaaa ggcgatttct tctataacta tctagcagtt
     2521 gtctttgctc ctattgcagg tgtactgcgt tttgggacgg cttacataac ggaaattgtc
     2581 ttgcctcgaa aggcagccga aatcgctgaa aagcgtaaag caggcaaaaa ttcaaaataa
     2641 aagagtccgg tgaagttcat cggatttttg tattatactc aatgaaaatc aaag
//
LOCUS       DAVAZV010000097         2607 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVAZV010000097 DAVAZV010000000
VERSION     DAVAZV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2607
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.097"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            114..1031
                     /locus_tag="VQT46_002080"
                     /pseudo
     CDS             114..1031
                     /locus_tag="VQT46_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822901.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQT46_002081"
     CDS             complement(1071..2015)
                     /gene="manA"
                     /locus_tag="VQT46_002081"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET2372031.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTILVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2147..2428)
                     /locus_tag="VQT46_002082"
     CDS             complement(2147..2428)
                     /locus_tag="VQT46_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET2372032.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDSVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            2493..>2607
                     /locus_tag="VQT46_002083"
     CDS             2493..>2607
                     /locus_tag="VQT46_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET2372033.1"
                     /translation="MKSTKEEIQTIKTLFKDSRTAKYHKCLQIILFRLMGKS"
BASE COUNT          698 a          606 c          477 g          826 t
ORIGIN      
        1 aaaagtcgtg cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcatca ttcatagaac tactatgcca tattttgttt cgcaggaagt ctgatcattt
      121 caaatccagc cattgctcta ggagctcaag cgacctttat cctattgaat atcttcattg
      181 tatcacgtgg ggttcaaaaa gggattgaaa gagcttcgaa agtcatgatg cccctgctct
      241 ttatcatctt tgtcgtcatc atcgaacgct ctctcagttt gccaaatgcc atggaagggg
      301 ttctttactt cctcaaacca gatttttcaa aactgactag cgctggtctc ctctatgctc
      361 tgagacaatc tttctttgcc ctctcactag gggttacagc catgttgacc tatgcttctt
      421 acttggacaa gaaaaccaat ctggtccagt caagaatctc catcgtagcc atgaatatct
      481 cggtatccat catggcaggt ctagccattt tccaagctcg gtcccccttc agactgaata
      541 ttgaaggggg accgagcttg gtctttatcg tcttgcctca actctttgac aagatgcctt
      601 ttggaaccat tttctatgtc ctcttcctct ttgcgactgt cacttcttct gtcgttatgc
      661 tggaaatcaa tgtagacaat atcaccaatc aggacaacag caagcgtgct aaatggagtg
      721 ttattttagg aattttgacc tttgtctttg gcattccttc agccctatct tacggtgtca
      781 tggcggatgt tcacattttt ggtaaagcct tctttgacgc tatggacttc ttggtttcca
      841 atctcctcat gccatttgga gctctcttcc tttcactttt tacaggctat atctttaaaa
      901 aggctcttgc aatggaggaa ctccatctcg atgaaagagc atggaaacaa ggactgttcc
      961 aagtctggct cttccttctt cgtttcgtca ttccaatcat catcgtggtc ttcatcgccc
     1021 aatttatgta atcaaaagga cttgagtaat gaactcaggt cctttctttt ttatggatga
     1081 ctaacaatta attctaaatc ttgcccttct agagtccaag attcaacatc acttggtagg
     1141 ataaagtgtc tccctttttg gattggatag tttttcccgt caacagttag ttgaccttga
     1201 ccagccaaga cactcaacaa gctgtagtca gctgtctttt caaagttaac ttttccagta
     1261 atttcccatt tgtaaactgc gaagaaatca ttggatacaa ggatagtgga acgtagatca
     1321 tctgctttga ttgtcactgg acggctattt gcgggttcac caatgttcaa gacatcgata
     1381 gatttttcaa ggtgaagttc acgtaaattg cccttgtcat ccttacggtc aaagtcatag
     1441 acacggtaag tggtatcgct agactgctgg gtttcaagaa tcaagatacc cgccccgata
     1501 gcgtgcatgg taccgcttgg tacatagaag aaatctcctg ctttaactgg cacttttgtc
     1561 aacagcgcat cccagttctt atcctcgatt tgctggcgga gttcttcttt tgacttggca
     1621 ttgtgaccgt agataatctc tgaaccttca tctgctgcaa tgatgtacca acattctgtt
     1681 tttccaagtt cgccttcatg ctcgagtcca taagcatcgt ctgggtgaac ttggacactg
     1741 agccagtcgt tggcatcgag gatcttggtc aaaagtggaa atacaggttc tggacgattg
     1801 ccaaataatt cacggtgttc cgcatacaaa gtagcaagat ctgttccctc gtaacgacca
     1861 ttggcaactt tagaaacacc atttagatga gctgagatag cccagtactc tccgactttt
     1921 tcacttggga tgtcgtagcc aaactcatca cgtagcttgg taccacccca gattttttct
     1981 tgcataactg attgtaaaaa taatggttct gacatcttaa tctcctgtct gatttttctc
     2041 ccctcattat agcaaaaaaa gagttccatt tgaactcttt tttacatctt ataaagcagg
     2101 gagaagattt tataaaaata gtaaacaaat gtgctctact cgatgcttac accattgcta
     2161 taaatgacat gtaccaatag aaggacttct tcttgctacg tttgagagtc ccatttccta
     2221 cattatctcg atctacatag ataaagccat agcgcttatt catttcccct gtgccagctg
     2281 aaaccgaatc gatacagccc catgtcgtat aaccaagcaa gtcaaccccg tctttgtaaa
     2341 tggcatctcg catggccttg atgtgggcct ctaagtaagt aatccgatag tcatctgcta
     2401 cataaccatt ctcatccggt gtatccatag caccgagtcc attttctacg ataatactat
     2461 actaaaatca aaaagcatta tataatagtg atatgaaatc aactaaagaa gaaatccaaa
     2521 ccatcaaaac actttttaaa gactctcgta cagctaaata tcataaatgc cttcaaatca
     2581 ttctatttcg tctgatgggc aaatctt
//
LOCUS       DAVAZV010000098         2398 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVAZV010000098 DAVAZV010000000
VERSION     DAVAZV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.098"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(26..428)
                     /locus_tag="VQT46_002084"
                     /pseudo
     CDS             complement(26..428)
                     /locus_tag="VQT46_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(373..555)
                     /locus_tag="VQT46_002085"
     CDS             complement(373..555)
                     /locus_tag="VQT46_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET2372034.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            912..>2398
                     /gene="pcpA"
                     /locus_tag="VQT46_002086"
     CDS             912..>2398
                     /gene="pcpA"
                     /locus_tag="VQT46_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HET2372035.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDGA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPETVKFYVTSEHIKDVLKSNLSTSNDIIVEKVDNIKQETD
                     VAKPKKNSNQGVVGWVKDKGLWYYLNESGSKATGWVKDKGLWYYL"
BASE COUNT          837 a          359 c          397 g          805 t
ORIGIN      
        1 tgagccttca tagcgtggca tttcttttta cttccgtcac atcaatcatt accgtgtcct
       61 cagaactgag aggagttctt gaaatcgtaa caccaccttt gaacaagagt tacttcaacc
      121 cattagctcc gacggattaa gttgctttcg tgaataccaa aatcagccgc aatttcttca
      181 taagtgcggt attctcgcac atattgaaga gtggccataa gaaggtcttc taggcttaat
      241 ttaggttttc gtccaccttt tgtgtgttta agttgataag ctgtttttaa cacagctaac
      301 atctcttcaa aagtggtgcg ctgaacacca acaagacgct taaatcgtgc atcggttagt
      361 tgtttacttg cttcataatt tcgcagggag tctattgact ctttggtagg tgtcaatgtt
      421 tttttcatct atcccgagaa ttattttccc gccatttgta tttgcaaatg ctgagtaggt
      481 ttcccagaaa gactctggaa gattgttttt agcttttttg tattctaaat caaccccttc
      541 aaattttaag tccatatttt tcctttacat ctgttttttg tggttctggt atttgttcaa
      601 gttgagtgat aatatagcga attgaatttc gagagttttt actcagttaa tttctttttt
      661 aacccacttt aatttctttt ttaacccact ttaatttctt ttttaacacg ggttaaaaaa
      721 gaaattaaag tgggttaatt tttcttgact taaaatttaa aaatgatata ctgtgtttat
      781 ggagagatga caatttataa aatgtactac tctattctac tagataatga ttgaataaaa
      841 ctttttataa caacggctag caaagttata attttatatc tattagaaaa taaatatgta
      901 aggaaattta aatgaaaaaa actacaatat tatcattaac tacagctgcg gttattttag
      961 cagcatatgt ccctaatgaa ccaatcctag cagatactcc tagttcggaa gtaatcaaag
     1021 agactaaagt tggaagtatt attcaacaaa ataatatcaa atataaggtt ctaactgtag
     1081 aaggtaacat aggaactgtt caagtgggta atggagttac tcctgtagag tttgaagctg
     1141 gtcaagatgg aaaaccattc acgattccta caaaaatcac agtaggtgat aaagtattta
     1201 ccgttactga agtagctagt caagctttta gttattatcc agatgaaaca ggtagaattg
     1261 tctactatcc tagctctatt actatcccat caagcataaa aaaaatacaa aaaaaaggct
     1321 tccatggaag taaagctaaa actattattt ttgacaaagg cagtcagctg gagaaaattg
     1381 aagatggagc ttttgatttt tctgaattag aagagattga attgcctgca tctctagaat
     1441 atattggaac aagtgcattt tcttttagtc aaaaattgaa aaagctaacc ttttcctcaa
     1501 gttcaaaatt agaattaata tcacatgagg cttttgctaa tttatcaaat ttagagaaac
     1561 taacattacc aaaatcggtt aaaacattag gaagtaatct atttagactc actactagct
     1621 taaaacatgt tgatgttgaa gaaggaaatg aatcgtttgc ctcagttgat ggtgttttgt
     1681 tttcaaaaga taaaacccaa ttaatttatt atccaagtca aaaaaatgac gaaagttata
     1741 aaacgcctaa ggagacaaaa gaacttgcat catattcgtt taataaaaat tcttacttga
     1801 aaaaactcga attgaatgaa ggtttagaaa aaatcggtac ttttgcattt gcagatgcga
     1861 ttaaacttga agaaattagc ttaccaaata gtttagaaac tattgaacgt ttagcctttt
     1921 acggtaattt agaattaaaa gaacttatat taccagataa tgttaaaaat tttggtaaac
     1981 acgttatgaa cggtttacca aaattaaaaa gtttaacaat tggtaataat atcaactcat
     2041 tgccgtcctt cttcctaagt ggcgtcttag attcattaaa ggaaattcat attaagaata
     2101 aaagtacaga gttttctgtg aaaaaagata catttgcaat tcctgaaact gttaagttct
     2161 atgtaacatc agaacatata aaagatgttc ttaaatcaaa tttatctact agtaatgata
     2221 tcattgttga aaaagtagat aatataaaac aagaaactga tgtagctaaa cctaaaaaga
     2281 attctaatca gggagtagtt ggttgggtta aagacaaagg tttatggtat tacttaaatg
     2341 aatcaggttc aaaggctact ggttgggtta aagacaaagg cttatggtat tacttaaa
//
LOCUS       DAVAZV010000099         2307 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVAZV010000099 DAVAZV010000000
VERSION     DAVAZV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2307)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2307)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2307
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.099"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(57..176)
                     /locus_tag="VQT46_002087"
     CDS             complement(57..176)
                     /locus_tag="VQT46_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET2372036.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            complement(280..429)
                     /gene="blpO"
                     /locus_tag="VQT46_002088"
     CDS             complement(280..429)
                     /gene="blpO"
                     /locus_tag="VQT46_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET2372037.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            complement(673..876)
                     /gene="blpN"
                     /locus_tag="VQT46_002089"
     CDS             complement(673..876)
                     /gene="blpN"
                     /locus_tag="VQT46_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET2372038.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            complement(892..1146)
                     /gene="blpM"
                     /locus_tag="VQT46_002090"
     CDS             complement(892..1146)
                     /gene="blpM"
                     /locus_tag="VQT46_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET2372039.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            complement(1296..2100)
                     /locus_tag="VQT46_002091"
     CDS             complement(join(1296..1730,1732..2100))
                     /locus_tag="VQT46_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET2372040.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEEIAADFGIHESNLLRRSQWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRPKKELANDSGKKKCHAMKTQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTSRKSSKLKPLTVEDKACNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
BASE COUNT          728 a          498 c          329 g          752 t
ORIGIN      
        1 attaaagaaa ctcccctgta aattaagcta gcaaatacag gggagaaatt tattttttag
       61 agagtactat ccgtatcctt tttggaagat tttgaaaata tttttctaat taagtcatcc
      121 atataaggac caaatatacc aactactaaa ccaataataa aacttttaaa atccataatt
      181 accaccaaca tattgctgca taggctacac ctccaagtat agctccacct gcagcaccag
      241 ttacacctat tcctatagca aatggtccca atagaaatgt caaaccgttg ttgcacaccc
      301 atcaattgcg ccatatgcaa cccctgctgc acaactaatt tttcttcccc aatcaatatc
      361 tccaccttca acgcaagcaa gcatttcatt atccataact gcaaattgtg acatcatttt
      421 tgtatccata tagtatatca cttttcagtt acggaacaag tttaatataa aaattatcaa
      481 aaaaacatag gcaataaaga gaaaaattaa tttatcatag attagaaata atatgacaaa
      541 acaattcaat gatgttaatt caatagtctt ttgtttttta tcggagatac ttatggatag
      601 ataaataaga taggtttgaa aagcgaagag aataataaag aatatagcct tcataaaatt
      661 tagctttcat ttttatgatg tagcggtata ggctaaatat ccacaaacca ctgctcctcc
      721 aattcctcct attgcagcgc cccatggtcc tagaagtctc ccatatttca ctccacccgc
      781 tgcacaacct aaagcagcaa ctacagctgc tcctccggaa ttacctccat aaacctcact
      841 cagcattgtt tcatttatat tacaataagt attcatacaa gtctcctttt attaaaatcc
      901 acccgttgcc cctgttactc ctgcccaaag atccacacca aatttagctc ctatgtatcc
      961 acatgctccc ataaatggtg ctccaacacc actcgcagca caaatagctg tccctagccc
     1021 ccagccacca aaagcagcac caccaccttc caagacatta gtttgccaat tattcttgcc
     1081 tccttcaata ctagataaca tagttatatc catttcatga aattgttcca taatttttgt
     1141 atccatgaca aatactcttt tttattttta atttttgtct tgttgtaact ttgacaagtt
     1201 tagtatatca tcgtttttta aaatttttca tccagatctt gaatagtcat cgaaacgtct
     1261 tgaattgcaa aaattacatt agacttcctg caaaactaga atcctagttc atgattgata
     1321 ataccagcac tcaaattcat tcgtaatccg aagcgtttac gatgatttcg ataggttgtt
     1381 gaaaacattt taaacgtttt tactttggca aagatgttct caaccttgct tctctcctta
     1441 gatagcgcat ggttacaggc tttatcttca actgttagcg gtttgagttt gctggattta
     1501 cgtgaagttt gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag
     1561 attttaccag cttgtccgat atttctgcga ctcattttga acaacttcat atcatgacaa
     1621 tagttcacag tgatatccaa agaaacaatt ctcccttgac ttgtgacaat cgcttgagtc
     1681 ttcatagcgt ggcatttctt tttaccagaa tcattcgcta attctttttt tagggcgatt
     1741 gatttgtact tccgtcgcat caatcattac cgtgtcctca gagctgagag gagttcttga
     1801 aatcgtaaca ccactttgaa caagagttac ttcaacccat tggctccgac ggagtaagtt
     1861 gctttcgtga ataccaaaat cagccgcaat ttcttcataa gttcgatatt ctcgcacata
     1921 ttgaagagta gccataagaa ggtcttctag gcttaattta ggttttcgtc caccttttgc
     1981 gtgtttaagt tgataagctg tttttaatac agctaacatc tcttcaaaag tggtacgctg
     2041 aacaccaaca agacgcttaa atcgtgcatc agttagttgt ttacttgctt cataattcat
     2101 agaactatag taaaatgaaa taagaacagg ataaatcgat caggacagtc aaatcgattt
     2161 ctaacaatgt tttagaagta gaggcgtact attctagttt caatatacta tactatacca
     2221 tattttgttt cgcagggaat ctattataaa agggtaagta ttgcaaaaac acttaccctt
     2281 ttcttttata cttcattaag ctctact
//
LOCUS       DAVAZV010000100         1880 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVAZV010000100 DAVAZV010000000
VERSION     DAVAZV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1880
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.100"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1625
                     /gene="phtA"
                     /locus_tag="VQT46_002092"
     CDS             <1..1625
                     /gene="phtA"
                     /locus_tag="VQT46_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET2372041.1"
                     /translation="TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRT
                     ARGVAVPHGDHYHFIPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPS
                     PGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLS
                     KQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERL
                     NDESTNKEKLVDDLLAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIF
                     DEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKAN
                     PTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDH
                     TYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKAD
                     EEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQ
                     IMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1783..>1880
                     /locus_tag="VQT46_002093"
     CDS             1783..>1880
                     /locus_tag="VQT46_002093"
                     /inference="COORDINATES: protein motif:HMM:TIGR01363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2372042.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTV"
BASE COUNT          667 a          343 c          365 g          505 t
ORIGIN      
        1 acactaacag tcaagcaagt caaagtaatg acattgatag tctcttgaaa cagctctaca
       61 aactgccttt gagtcaacga catgtagaat ctgatggcct tgttttcgac ccagcgcaaa
      121 tcacaagtcg aacagctaga ggtgttgcag tgccacacgg agatcattac cacttcatcc
      181 cttactctca aatgtctgaa ttggaagaac gaatcgctcg tattattccc cttcgttatc
      241 gttcaaacca ttgggtacca gattcaaggc cagaacaacc aagtccacaa ccgactccgg
      301 aacctagtcc aggcccgcaa cctgcaccaa atcttaaaat agactcaaat tcttctttgg
      361 ttagtcagct ggtacgaaaa gttggggaag gatatgtatt cgaagaaaag ggcatctctc
      421 gttatgtctt tgcgaaagat ttaccatctg aaactgttaa aaatcttgaa agtaagttat
      481 caaaacaaga gagtgtttca cacactttaa ctgctaaaaa agaaaatgtt gctcctcgtg
      541 accaagaatt ttatgataaa gcatataatc tgttaactga ggctcataaa gccttgtttg
      601 aaaataaggg tcgtaattct gatttccaag ccttagacaa attattagaa cgcttgaatg
      661 atgaatcgac taataaagaa aaattggtag atgatttatt ggcattccta gcaccaatta
      721 cccatccaga gcgacttggc aagccaaatt ctcaaattga gtatactgaa gacgaagttc
      781 gtattgctca attagctgat aagtatacaa cgtcagatgg ttacattttt gatgaacatg
      841 atataatcag tgatgaagga gatgcatatg taacgcctca tatgggccat agtcactgga
      901 ttggaaaaga tagcctttct gataaggaaa aagttgcagc tcaagcctat actaaagaaa
      961 aaggtatcct acctccatct ccagacgcag atgttaaagc aaatccaact ggagatagtg
     1021 cagcagctat ttacaatcgt gtgaaagggg aaaaacgaat tccactcgtt cgacttccat
     1081 atatggttga gcatacagtt gaggttaaaa acggtaattt gattattcct cataaggatc
     1141 attaccataa tattaaattt gcttggtttg atgatcacac atacaaagct ccaaatggct
     1201 ataccttgga agatttgttt gcgacgatta agtactacgt agaacaccct gacgaacgtc
     1261 cacattctaa tgatggatgg ggcaatgcca gtgagcatgt gttaggcaag aaagaccaca
     1321 gtgaagatcc aaataagaac ttcaaagcgg atgaagagcc agtagaggaa acacctgctg
     1381 agccagaagt ccctcaagta gagactgaaa aagtagaagc ccaactcaaa gaagcagaag
     1441 ttttgcttgc gaaagtaacg gattctagtc tgaaagccaa tgcaacagaa actctagctg
     1501 gtttacgaaa taatttgact cttcaaatta tggataacaa tagtatcatg gcagaagcag
     1561 aaaaattact tgcgttgtta aaaggaagta atccttcatc tgtaagtaag gaaaaaataa
     1621 actaatgaaa aatgaaagtc tcgataaaga ggctttcatt tttattatgt atatatgtaa
     1681 aattcttgac aagcaatatt aaaaagagta aactattaac tagttaatta accggtttgt
     1741 tactttatag tgaatcaaat atacttaaga aaagaggaaa gaatgaaaat caataaaaaa
     1801 tatctagctg ggtcagtagc tacacttgtt ttaagtgtct gtgcttatga actaggtttg
     1861 catcaagctc aaactgtaaa
//
LOCUS       DAVAZV010000101         1671 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVAZV010000101 DAVAZV010000000
VERSION     DAVAZV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.101"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            100..1575
                     /locus_tag="VQT46_002094"
     CDS             100..1575
                     /locus_tag="VQT46_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET2372043.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNIVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
BASE COUNT          474 a          335 c          334 g          528 t
ORIGIN      
        1 tccagtattt gacaatattg aagcagctat taaagaacac ggattaagct aattctaatt
       61 tgttaacatt catataacat aaaaaaggga ggaactgtta tggatgcaat ctttgaccta
      121 atcggaaagg ttttcaatcc cattttagaa atgggtggac ctgtcatcat gttaatcatt
      181 ttgacagtat tggctttact ttttggagtg aaattctcca aagcgcttga aggtggtatc
      241 aaacttgcca tcgctcttac aggtatcggt gctatcatcg gtatgctaaa tggtgctttc
      301 tcagcatcac ttgcaaaatt cgttgaaaac actggtatcc aattgagtat taccgacgtt
      361 ggttgggcac cactcgcaac aatcacttgg ggttctgctt ggacactata cttcttgctc
      421 atcatgttga ttgtcaacat agtgatgcta gctatgaaga aaacagatac acttgacgtt
      481 gatatctttg atatctggca cttgtctatc acaggtctct tgattaaatg gtatgctgat
      541 aacaatggtg tgagtcaagg ggtttcactc tttattgcta cagcagctat cgtccttgtc
      601 ggtgtgttga aaattatcaa ctctgacttg atgaaaccta catttgatga ccttcttaac
      661 gccccaagtt catcaccaat gacatcaact cacatgaact acatgatgaa cccagttatc
      721 atggttttgg ataagatttt tgaaaaattc ttcccaggcc ttgataaata tgactttgat
      781 gctgctaaat tgaacaagaa aatcggtttc tggggatcta aattcttcat cggtttcatc
      841 cttggtatcg ttatcggtat tatgggaact ccacatccaa ttgcaggtgt tgcagatgca
      901 gataaatggc gtcttgttat caaaggatgg ttgtctcttg gtttgactgc cggtgtatct
      961 ttggaactct tctcacttat cggttcatgg ttcatcgcag ccgtagaacc actatcacaa
     1021 ggtattacaa acgttgctac taaacgtctt caaggacgta aattcaatat cggtcttgac
     1081 tggccattca tcgctggtcg tgctgaaatc tgggcttgtg ccaacgtact tgcaccaatc
     1141 atgttgattg aagcagtgct tctttcaaaa gttggaaatg gtatcttgcc acttgcaggt
     1201 atcatcgcta tgggtgttac tccagctctc ttggttgtaa ctcgtggtaa attgctccgt
     1261 atgattatct tcggaacact cttgttgcca ctcttccttc tttcaggtac acttattgca
     1321 ccatttgcaa cagaacttgc taaaggtgta ggtgccttcc cagaaggtgt gagccaaact
     1381 caattgatta ctcactctac tcttgaagga ccaatcgaaa aacttcttgg ttggacaatt
     1441 ggtaacacta caactggtga tatcaaagca atccttggtg cagtagtctt ccttgtattc
     1501 tatatcggta tctttgcttg gtacagaaaa caaatgatca aacgtaacga agagtacgca
     1561 gcaaaagcaa aataatgcgc tcctataaaa tataaactca atgaaaatca aagagcaaac
     1621 taggaaacta gccacaggtt gctcaaaaca cagttttgag gttgtagata a
//
LOCUS       DAVAZV010000102         1651 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVAZV010000102 DAVAZV010000000
VERSION     DAVAZV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.102"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            108..407
                     /locus_tag="VQT46_002095"
     CDS             108..407
                     /locus_tag="VQT46_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic biosynthesis protein"
                     /protein_id="HET2372044.1"
                     /translation="MDSYAINFWESKGVGIDKKILEFIQKNITVIKNKNFLNKDFDIY
                     VKKIHNLFFVISTLVSKEQYMGIVSSQIHMFANRMGISPTIEVTMLDFFLREDSD"
     gene            409..1179
                     /locus_tag="VQT46_002096"
     CDS             409..1179
                     /locus_tag="VQT46_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="HET2372045.1"
                     /translation="MEKYFFDISIFEKIKKVLSYQSKYWEISKPRDKYSFKSQNRISG
                     SNSIKFKDFELDYELESLGKILLKRRSFLLNEFDKNASFDKLIYLLKTVFSPTNCKFV
                     FGEEVPLFSYPTSGALNSITPFVYIDNMDEVKNGIYEVKYDGLEFKKSMNIIDLETFT
                     PITSKNSDVQNNSFKKVNMIIMLCSNYENIFNKYGLLAYRLLHLEAGHIAQNIQLVST
                     ALGIKSLPMGGWFDDKIETFINEISDKKNIYLYAIAVG"
     gene            1199..1363
                     /locus_tag="VQT46_002097"
     CDS             1199..1363
                     /locus_tag="VQT46_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372046.1"
                     /translation="MNAEDKFRELENENKLLKLHNKELENEIQNGWKFWIWVTVPILG
                     LIYAIIQKIF"
BASE COUNT          608 a          181 c          269 g          593 t
ORIGIN      
        1 ataactatta ttacgaaaaa aaattcttgt gtaaaattct attgactttc tatattattt
       61 ttgtatttca taacgaatgt aatttaacaa gtgaagaaat tttaaagatg gattcctatg
      121 ctattaattt ctgggagagt aaaggggtcg gtattgacaa aaaaatcttg gaatttattc
      181 aaaaaaatat tacagttatt aaaaataaaa attttttgaa taaagatttt gatatttatg
      241 ttaaaaagat tcataattta ttctttgtca tttctacttt agtttcaaaa gagcaataca
      301 tggggatagt ttcttcccaa atacatatgt tcgcaaatag gatgggaatt tctcccacca
      361 ttgaagttac catgctagat ttttttctga gggaggattc tgattaatat ggaaaaatat
      421 ttttttgata tttctatttt tgaaaaaata aaaaaagtat tatcatacca atctaaatat
      481 tgggaaatat cgaagcctag ggataagtac agtttcaaaa gtcaaaatag aatatctggc
      541 tctaatagca ttaaatttaa agattttgag ttagattatg aactggagtc acttggtaaa
      601 atacttttaa aaaggagatc gtttttacta aatgaatttg ataagaatgc gagttttgac
      661 aaactgattt acttgttgaa aactgtattc tctcctacaa attgcaagtt tgtatttgga
      721 gaagaggttc ctttatttag ctatcctaca tcaggtgcgt taaattcaat tactcctttt
      781 gtttatattg ataatatgga tgaagtaaag aatggtatat atgaagtaaa gtatgacgga
      841 cttgaattta aaaaaagtat gaatattata gacttagaaa catttacccc aataacaagt
      901 aaaaacagtg acgtacaaaa taattcattt aaaaaggtaa atatgataat tatgttatgt
      961 tcgaattatg aaaatatttt caataaatat ggattattag cttatcgact tttgcattta
     1021 gaggctggtc atattgcaca aaatatccag cttgtttcta ctgcgctagg aataaaaagt
     1081 ttaccgatgg gaggttggtt tgatgataaa atagaaactt ttattaatga aattagtgat
     1141 aaaaaaaata tttatctcta tgcaattgca gttggataaa tttaaggagg aagtgtagat
     1201 gaacgcagag gataaatttc gcgaactaga aaatgaaaat aaacttctaa aacttcataa
     1261 caaggagctt gagaatgaaa ttcaaaatgg atggaaattt tggatatggg taactgtccc
     1321 tattttaggt ttgatatatg ctattattca aaaaattttt taattatgct agtttgtcag
     1381 gttgagtagt ttttgttcaa aatttaataa acttttttca atgaagatta tctaaagatt
     1441 gcttctcaga tgagaatggc ttctctatct tatataaatt atcttcatag agtgtcctgt
     1501 tattcatgtt atcacagaat agatagtttt tttggctcta taatatttgt agtgggtaaa
     1561 tcccctatag atattatgga gcctattttt gtgtagaaaa aaagtcccat atcatctata
     1621 atgaaaagca accaaactat cattagaaag a
//
LOCUS       DAVAZV010000103         1642 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVAZV010000103 DAVAZV010000000
VERSION     DAVAZV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1642
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.103"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..749)
                     /locus_tag="VQT46_002098"
     CDS             complement(<1..749)
                     /locus_tag="VQT46_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2372047.1"
                     /translation="MCYTCCSTTNTRKAQRCKTIILQKANKGKSNREIASLLGKAPQT
                     IHTEIKRRTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHN
                     QKFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAG
                     QSIEQRLEAINFRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVV
                     NQALKLILKQHKILSITADNGTEFNRLSNVFS"
     gene            complement(1123..1521)
                     /locus_tag="VQT46_002099"
     CDS             complement(1123..1521)
                     /locus_tag="VQT46_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET2372048.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          468 a          322 c          276 g          576 t
ORIGIN      
        1 gaaaatacat tagacaagcg attgaattcc gttccattat ctgccgtgat ggaaagaatc
       61 ttgtgttgtt ttaagatgag ttttagagcc tgattgacca cctcagcact tttatttgga
      121 atcaatcgga tgatctgatg tctacttttt cgatccgtca agacaagcaa gcagtagttt
      181 ttcgctctcg taagtagaac tgtatcaatc tcataatgcc cattctccaa gcgaaaattg
      241 atagcttcaa gccgctgttc gatggattga ccagcaggtt taaagttggt gctagcctgt
      301 ttcttaagcg cttttccttt tctagggtaa ggcaaatcct gcttgcttaa ccccaatttt
      361 ccatgatgaa tccaatagta aatggttgaa attcccacgt taaccccttt agccataacc
      421 atcatttcag gcgaaaattt ttggttatga tagtggagaa tcttttcctt tagttccttg
      481 gtcaagcttg atttcttgac cgagcgcttg cgattgtttt cataagactg ttgagcatag
      541 tcggcagaat aaacctcttt gaagcgccct tttccaagac attgtcggac tgtcctacgc
      601 ttgatttcag tgtggatagt ttgaggagct tttccaagta gagaggcaat ttctctattt
      661 gatttccctt tgttcgcctt ttgtagtata atggttttgc atctctgtgc ctttcttgtg
      721 tttgtggttg aacaacaagt ataacacaaa ggtgttttct tatgcctaca agagctttca
      781 ttatttccat tttcttttgg atttcactct attctgaaaa acttgtgtat atttactgaa
      841 gctagcaagt cttacctgta aatttaatga aagcaacaca aaatccgaga ggggaatctc
      901 ggattaatgt caatttaaaa agatagagag tttttagttt aaataaattg ttttaaaata
      961 tcaacaacat cacttctttt cttaacctga taagccttga ttcctaattt tggggctacg
     1021 attatattgt cctcaatatc gtctagaaag acacaatttc taggttataa ctggtattta
     1081 tcgatagtta ctcatatata tcagtccacc tccatactca ccttacagat tcttttgata
     1141 ataatatctt tgcctaatgt agagatagtc ttgcaaagaa aaaacttcct tgtagccatg
     1201 tttctgataa aagtccggtg cctggaactg gtaagtattg acaaaggcaa aacaacaatt
     1261 tcgattctta gcttcacttt ctgcctgttg caatagtttt gaaccgattc cttgccctcg
     1321 cagttcctct tttacaaaca aatactcgat ttctagccaa tttccaaaag tctctgctat
     1381 caaacccgca aggagattgc ccttttcatc ttcgacataa agattaagtg gctcactttc
     1441 agcctcttct ctttttgaac ggttataaac acgaatcaga ttccctattt cttgcgattt
     1501 atgtgattcc ttattttcca atctaaagta taatgaaatg aaataaaaca tgcgcaaatc
     1561 gattaaggaa tttaatctaa tttctaacaa tgtcttagaa atcaaagtgt actattttaa
     1621 cttcaatgca ctatacatct aa
//
LOCUS       DAVAZV010000104         1586 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVAZV010000104 DAVAZV010000000
VERSION     DAVAZV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.104"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            84..491
                     /locus_tag="VQT46_002100"
     CDS             84..491
                     /locus_tag="VQT46_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET2372049.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKIG"
     gene            656..955
                     /locus_tag="VQT46_002101"
     CDS             656..955
                     /locus_tag="VQT46_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET2372050.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVNEANIKTLYSEKLIGISIPIK"
     gene            1216..1539
                     /gene="tnpB"
                     /locus_tag="VQT46_002102"
     CDS             1216..1539
                     /gene="tnpB"
                     /locus_tag="VQT46_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET2372051.1"
                     /translation="MMIVLSDLGQVHLVCGKTDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDRFKALYWDGQGFWLLYKRFENGRLTWPSTEKDVKALTSEQVDWLMKGFS
                     ITPQI"
BASE COUNT          544 a          314 c          282 g          446 t
ORIGIN      
        1 actataataa taacgatact agataatgag gaaaatgcaa tggcaaaccc aactttcgga
       61 gaaaaaaagc gaatacagac tatattgctc gctatggcgt atatgcagtt atccctaatc
      121 ctgaacaaaa acaaattgtt cttgttcaag aaccaaatgg tgcttggttc ctaccatgtg
      181 gagaaattga agcaggtgaa aatcatcagg aagccctaaa gcgtgagttg attgaagagc
      241 ttggtttcac agcagaaatt ggtacctatt acggacaagc tgacgaatat ttctattctc
      301 gtcatcgtga tacctactac tacaatcctg cctacctcta tgaagcaact tctttcaaag
      361 aagtacaaaa gccactagaa aactttaatc atattgcctg gttccctatt gacgaggcta
      421 tccaaaacct taaacgtggt agccataaat gggccattga atcttggaaa aaacagcata
      481 agattggcta atactcttcg aaaataaaat tcaaaccacg tcagcgtcgc cttaccgtac
      541 tcaagtatag cctgcggcta gcttcctagt ttgctctttg attttcattg agtataaatc
      601 aagcgacttt attcaaaaag tgctataata gaattagaaa atcggaggaa atattatgaa
      661 gcttatcaat acgacaaact cacactcgca acttgtaaaa agtcaactag aaagtaccga
      721 tgcaaccctt gttgaggttt attctgcagg gaatacagat gttattttta cccaagctcc
      781 gcttcactat gaaatcctca tctcaaacaa acaccgtgct attcgtgagc ctgaaatcga
      841 aaccattcaa gaatttttct tgaaacgtaa aattgataag acctctgtta atgaagccaa
      901 tatcaagaca ctctactcag agaaattaat tggaatttca atcccaatca agtaagaaaa
      961 ttgagtaaaa actcgatttg agagaaagtc caataagtct ttccataaca aaacgcatag
     1021 taacaagagt ttctacaccc actattatac gtttttatca ttttgaaatc tgctgctaat
     1081 caatgaagaa gcaaagatca aactaggcag ctagttacaa gttacgtaag cgcgtcataa
     1141 caaggtatct atcctaattc cccaacttcc agtatactag ataaaaaata attatcagag
     1201 gaaaggtatt gtactatgat gattgtacta agtgatttag gtcaagttca ccttgtttgt
     1261 ggcaagacag atatgaggca gggaatagac tcattagcct atgtagttaa aacccacttt
     1321 gaattggatc ctttctccgg tcaagtcttt ctcttttgtg gtggacgtaa agaccgcttt
     1381 aaagcccttt actgggatgg tcaaggattt tggctactat ataaacgctt tgagaacggc
     1441 agactgactt ggcccagtac agaaaaggat gtcaaagctc tcacatctga acaagtagac
     1501 tggcttatga agggcttttc tatcactccc caaatatagt ggatttaaac tagaatagta
     1561 cacctctact tctaaaacat tgttag
//
LOCUS       DAVAZV010000105         1455 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVAZV010000105 DAVAZV010000000
VERSION     DAVAZV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.105"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQT46_002103"
     CDS             complement(412..804)
                     /gene="rpsI"
                     /locus_tag="VQT46_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET2372052.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQT46_002104"
     CDS             complement(824..1270)
                     /gene="rplM"
                     /locus_tag="VQT46_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET2372053.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
BASE COUNT          420 a          290 c          279 g          466 t
ORIGIN      
        1 cccaaactct tcacacaaga gttctaactt acccattcta tggaatcttg cattatccat
       61 aatatagtag attgaaacta gaatagtaca cctctacttc taaaacattg ttagaattcg
      121 atttgactat cctcggtttg tcctattctt atttcacctt actataaaaa taaggtaaac
      181 ttttcaaaaa aacacgaaaa aagcacccat agggcaaacc tttgagtgct ttgaaacatt
      241 gatataattg tattgattag cgttttgagg caactgacct tgtcaggttg cagccacatt
      301 tgtaagcaac taaagtcgca acaactgtgt caattgcacc aatttagtaa gaaagtataa
      361 aaaaagaaca ccccgaaagg tgctctgtat aagtatagta attctttcga attaacgttt
      421 actaaattgt gatgctttac gagctttctt aagacctggt ttcttacgtt caactttacg
      481 tgagtcacgt gtaagaagtc ctgcgcgttt caatgaatcg cggaagtctg ggtctacttg
      541 aagaagggca cgagcgatac cgtgacggat agctcctgat tgaccagcgt atccaccacc
      601 tacaacgtta acgaaaacgt cgtatgaacc tacagttgaa gtaactgcga atggttggtt
      661 gatgacaaga cgaaggtcag catgtgggat gtactcttca acatcttttt tgttaacagt
      721 gattttacca gttcctggaa caaggcgaac gcgtgcaaca gcgtttttac gacgtccagt
      781 acctgcatat tgtgcttgtg acatacttta tttgttcctt tccttagata agtcctgaaa
      841 tgtcaagaac ttctggttgt tgtgcagcat gagtgtgctc agctccaaca aatactttca
      901 acttcatacc ttgagcgcgt ccaagtgtat tgtgtggaag cataccttta actgatttct
      961 caatcaaacg tactgcattt ttagaacgaa gttcacctgc agagatttgt ttcaatccac
     1021 ctgggtggtt tgagtgagtg tagtagattt tatcagttgc ttttttacca gtcaatttaa
     1081 ctttttcagc attgataaca atcacgaagt cacctgtatc agtgtgtggt gtaaatgttg
     1141 gtttgttttt tccgcgaagt acgctagcaa ctactgcaga aagacgtcca agtggtacat
     1201 cagttgcgtc aactacgtac catttacgtt caacttggcc tggtttagcc ataaatgttg
     1261 ttttgttcat gatttctcct atatatagtt cgatttttgt ttacggtgat gggtgttcct
     1321 tcccatcgaa aagtatttgg aaggttccgg ggcctttcaa atggggtaaa caataccgcc
     1381 tactatcata ccaaatttca cccctaaaag tcaatagata tgaaaaatat ttttcggtaa
     1441 cttctcaaag taact
//
LOCUS       DAVAZV010000106         1286 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVAZV010000106 DAVAZV010000000
VERSION     DAVAZV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.106"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(601..1286)
                     /locus_tag="VQT46_002105"
                     /pseudo
     CDS             complement(601..1286)
                     /locus_tag="VQT46_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          360 a          257 c          269 g          400 t
ORIGIN      
        1 gaagtttcct cactactatg ggctcggctg acttctcatg attcgttgtt actacgcttt
       61 cggcgctcat gagacctcac gggataagcc gtacatcttt cctcgtttat acaagatatg
      121 aggacgttaa aaggttacaa tgaaaatagg aaatctgacg cagagtcttt agactctagg
      181 aagatttatc tttttcacat agaccttagt ccgaattcaa ttactctcgt gatttacgca
      241 tataggttac gactaccttt ttggacttta gagttttaag cccccttatc cgctgtatac
      301 gccttactat cacgttcctg ttcgtagagc ctcgatttcg ctatcccttc ctctgacgat
      361 tcttatttcc tgcgtcagac ttaaaacggt ctatccccag accgttttaa tccgctacct
      421 cacgatagtc aggcttggga atcgctattg ggttcaccgg tagcaggtgc ccacggagga
      481 cttacacctc agatgcacga catgcccgtc gtacttaaaa tcagcctaaa tgattcaggc
      541 tgatttttct attgattcaa aaaaacggct ctttgtcaac tgtagtgggt tgaagaaaag
      601 ctaagatcga gaaaggacaa atttcgtcct ttcttttttg atattcagag cgataaaaat
      661 ccgttttttg aagttttcaa agttccgaaa accaaaggca ttgtgcttga taagtttgat
      721 gagattattg gtcgcttcca atttggcgtt tgaatagggt agttgaaggg cgttgataat
      781 cttttcttta tctttgagga aggttttaaa gacagtctga aaaataggat gaacctgctt
      841 cagattgtcc tcaataagtc cgaaaaattt ctctggttcc ttattctgga agtgaaaaag
      901 caagagctga tagagctgat agtggtgttt caagtcttcc gaatagctca aaagcttgtc
      961 taaaatctct ttattggtta aatgcatacg aaaagtagga cgataaaaac gcttatcact
     1021 cagtttacgg ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
     1081 ggattttcga tgaaactgat tcatgattta aacacgcaca cgactcatag cacggctaag
     1141 atgttgcaca atgtgaaagc gatcaagaac gattttagca ttcgggagtg aaacagtctg
     1201 ggagactgtt tcagcctgag cctagaaatt tgaaagcgaa gctgtctagc taagtcatag
     1261 taagggctaa acatatccat agtaat
//
LOCUS       DAVAZV010000107         1187 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVAZV010000107 DAVAZV010000000
VERSION     DAVAZV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1187
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.107"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..311)
                     /locus_tag="VQT46_002106"
                     /pseudo
     CDS             complement(1..311)
                     /locus_tag="VQT46_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(547..858)
                     /locus_tag="VQT46_002107"
     CDS             complement(547..858)
                     /locus_tag="VQT46_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372054.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYVCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(873..>1187)
                     /locus_tag="VQT46_002108"
     CDS             complement(873..>1187)
                     /locus_tag="VQT46_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET2372055.1"
                     /translation="PEYKFVAEVVSYDDATQTATIRQRNVINEGDQVEFYGPGFRHFE
                     TYIEDLHDAKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKEDGTSVTV
                     RA"
BASE COUNT          363 a          238 c          203 g          383 t
ORIGIN      
        1 aagtcttgtt tgatagcttc aaacttttca ggactttcaa gataggcatc cacaaccgcc
       61 ttgtagcagt tggttactgt taatacatag tgaatagact ccatacgtcc ttcgattttt
      121 agactgtcca caccattttc aatcatatct ggaatgtggt caatcataga catgtcaacg
      181 gctgacattg aaaattcttc tggaatctca ccctgcaaac tcttacgttc tttcccaaat
      241 ggcatatcgt aaaggtcgta tttccaacgg catgactgag aacatccacc acggttggca
      301 tcacgcatac tctagacgca attctaatct tttagacttt gcataataac tgttaaacag
      361 ttgaaaatta acccagtttt aacaagtagt caaaatacca gataaaggaa aaaaagtctt
      421 taaaatctta aaaacgcata gtatcaggta ttgaacaatc ttgatattat gcgttttatt
      481 gtgggaagat ttacttcatt ttctcttgga attgagtttt ctcctacttc aaaactagat
      541 gatttgctat ttaaaatagc gttccttatg attttggcaa cctggattaa agcgagaaaa
      601 acaaaagggg caacttaagc tttctttata ttgcttatat gttagtagtt ttagacaaac
      661 accacataaa ataggcttat cctgtatcaa agataaggga tacggctcaa aagggtgatt
      721 ttctaatgaa tcatgacacc gataacaagc atagtacttt ttacaaacat agcattgtaa
      781 agcaataata tccagcttgc tatggtaatg aatgcatctt gtttgcttat ccactaagaa
      841 accctgtgcc tctatcattt ccttttcctt tcttaagctc gaactgtgac gctggttcca
      901 tcttccttat aaagattgat gagtccttct tttaatgcac gaaccatgtc tccagcttga
      961 acaggttgag gcaccttaat agtcaatagt tccattggat ttggagcgcg gtcgatttta
     1021 ttgcctttgg catcatgcaa atcttcaata taggtttcaa aatgacggaa acctggacca
     1081 taaaactcaa cttggtcccc ttcgttaatg acgtttcgtt gacgaatagt tgctgtttgt
     1141 gtcgcatcat cataagaaac cacttcagcg acaaacttgt actcagg
//
LOCUS       DAVAZV010000108         1142 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVAZV010000108 DAVAZV010000000
VERSION     DAVAZV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1142
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.108"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..1122
                     /gene="rlmD"
                     /locus_tag="VQT46_002109"
     CDS             <1..1122
                     /gene="rlmD"
                     /locus_tag="VQT46_002109"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET2372056.1"
                     /translation="CGGCQIMHLHYDKQLEFKTDLLHQALKKFAPAGYENYEIRPTIG
                     MQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELKDCLVQDKETQVIANRLAELL
                     TYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNRQLNLTQLVKELVKDFPEVVT
                     VAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSLSPRAFYQLNPEQTEVLYSEA
                     VKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDIIPEAIEDAKRNAKRMGFDNT
                     HYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLLDTILTYVPEKMVYISCNVST
                     LARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKKV"
BASE COUNT          387 a          196 c          243 g          316 t
ORIGIN      
        1 tgcggaggct gccaaatcat gcacctgcat tatgataagc agctggagtt caagacggac
       61 ttacttcatc aagcgctgaa aaaatttgct cctgcaggat atgaaaatta tgaaattcgt
      121 ccaactattg gaatgcagga accaaaatat tacagagcta agttacaatt tcagactcga
      181 aaatttaaaa atcaggtcaa ggcgggctta tatgcacaaa actctcacta tttagtagag
      241 ttgaaagact gcctggtaca agataaggaa acccaagtga ttgctaatcg cttagcagaa
      301 ttacttactt atcaccagat tccaatcacg gatgagagaa aagttctagg tgtccgtact
      361 attatggtcc gacgcgcgag aaagaccgga caggttcaga ttattattgt tacaaaccgc
      421 cagcttaatt taactcaatt ggtaaaagag ttggttaaag atttcccaga agttgtgaca
      481 gtagctgtta atacaaatac agctaaaacc agtgagatat atggtgaaaa gacagagatt
      541 atctgggggc aagagagtat tcaagaaggt gtactcaatt atgaattttc actatcccct
      601 cgagcttttt atcaactaaa tcctgagcaa acagaagtcc tctatagcga agcagtaaaa
      661 gcgctggatg ttgataaaga agaccatttg attgacgctt attgtggagt tggaacgatt
      721 ggatttgcct ttgcaaagaa agtaaaaaca ctcagaggta tggatattat tccagaagct
      781 attgaagatg ccaagcgaaa tgctaaaaga atgggatttg acaatactca ttatgaagct
      841 ggaacggcag aagagattat tcctcgttgg tacaaggaag gctaccgagc agatgctttg
      901 attgttgacc caccacgtac aggtctggat gataagttat tagatactat tcttacttat
      961 gtaccagaaa aaatggttta tatttcttgt aatgtttcga ccttggctcg tgatttggta
     1021 cgcttagtag aagtctatga tcttcattat atccagtcgg tcgatatgtt cccacataca
     1081 gctcgaactg aagctgttgt aaaattaata aaaaaagttt aaaaaaggtg ttgacaaaac
     1141 at
//
LOCUS       DAVAZV010000109         1138 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVAZV010000109 DAVAZV010000000
VERSION     DAVAZV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.109"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQT46_002110"
     CDS             complement(<1..990)
                     /gene="ltrA"
                     /locus_tag="VQT46_002110"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET2372057.1"
                     /translation="MSKLLDKILSRDNMLEAYNQVKSNKGSAGIDGITIEEMDGYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEIPKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSL"
BASE COUNT          298 a          247 c          204 g          389 t
ORIGIN      
        1 caatgagaaa tagtttatcc atcctcgaat agacaaattc agttgctcaa tacgtcttgt
       61 taggtctata ctccatttcc tctgtgttag tttcttcaat ttaagcttaa atctccaaac
      121 actatcttga tgtggacgac ttttccaacc atctgatgat ttccagaacc cgaaacctag
      181 atatttcaac tctcttggtc tggtaatctt agtcttggtc atgtttactt tcagacctag
      241 ccgtttctca ataaaacgac tgactgaata catcacacgc ttagcggctg cctcgcttcc
      301 gaccgtaatc acacaatcgt ctgcgtagcg aacaaatcga agccctctct tttctaattc
      361 cttgtccaat tcattaagca tgatattgga taagagagga gataaatttc ctccctgtgg
      421 cgtgccaact agcgttttat aacgttgacc gttaatgata acacctgaat gaagatattt
      481 acgaatcaag gattccgtat ctccgtcttc gataatgtta tgtactaagg acatcaatct
      541 atcttgagga actgtatcga aaaatttctc taggtctatg tccactatcc actcatagcc
      601 gtcatttaag tactctaaga gcttcatgat ggctttttca catgacctat ttggtctgaa
      661 tccatagctc gtatctgaga aatggggttc acaaataggg ctaataactt gaacaatggc
      721 ctgttgaatc attctatcca taactgttgg aattcctagt tggcggatgc ctccgtttgg
      781 tttgggaatc tcaactctaa gaactggttg aggcttatat tttctctgtt ttatcagttc
      841 cttagtcagg cgccagtttt gtctgagata gccatccatc tcttcgatag taattccatc
      901 aatcccagct gagcctttat tagattttac ttgattgtag gcttcaagca tattgtcgcg
      961 tgataatatt ttatctagca attttgacat gtgcctattc ctttcttgtt ttggtgcctg
     1021 agggacatct tatattggtg aaccttcatc tagtcaatac gtgacagagt ccagttctat
     1081 cagaccgttc gttttacaga cacaagtgaa gtaggattac ttcgattagt tgtttacc
//
LOCUS       DAVAZV010000110         1060 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVAZV010000110 DAVAZV010000000
VERSION     DAVAZV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1060)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1060)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1060
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.110"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            109..>1060
                     /locus_tag="VQT46_002111"
     CDS             109..>1060
                     /locus_tag="VQT46_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET2372058.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNENKSNREIAGLLGKAPQTI
                     HNEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
BASE COUNT          376 a          190 c          220 g          274 t
ORIGIN      
        1 aaacaggttc aagggttcct gttgtcaaat gaaatgtgat ttaaggtata agaaaacacc
       61 tctgtgctat acttgttgtt caccacaaac acaaggaaag gcacagagat gcaagaacat
      121 tataccccaa aagggaaaca tttgacaata gataaccgtc gcttgattga gcggtggaag
      181 aatgaaaata agtccaatcg tgaaattgca ggcttgttag gaaaggcgcc tcaaacgatt
      241 cataatgaag tcaaaagagg tacaacttta caacaagtga gaaaagggct atacaaaaag
      301 gtctattctg ccgattacgc acaaactgtt taccaattca atcgaaaacg gtcggtgaaa
      361 aagttaattt taacaaagga aatcagagag aagatcttac actatcataa gcaaaaattt
      421 tcgcctgaaa tgatggttaa caagaagcaa gtgaaagttg gtatttcaac catctactac
      481 tggtttcata atggtcattt aggattgacg aaggccgaca tgctttatcc cagaaaaagg
      541 aaaggtgtca agaagcaagc tagtccgaac tttaagccgg caggtaaatc tatcgaagaa
      601 cgtcctgacg ttattaatct tcgcttggaa aatggtcatt atgaaattga taccgtccta
      661 ctgactaaga taaaaaatta ttgcctgtta gtcttaaccg accggcggag cagacaccaa
      721 attataaggt taattccaaa taaaactgct gaatctgtca atcaggcgct tacgttacta
      781 ttaggggagc atcgtattct gtccattact gcagataatg gttcggagtt caaacgattg
      841 tctgaggtat ttcctgagga acatatctac tacgcacatg cttactcttc atgggagaga
      901 ggttcaaatg aaaatcataa tcgattaatt cggagatggt tacctaaagg aaccaagaaa
      961 acgactccga aagaagtagc ttttatcgaa aattggatta acaactaccc taaaaaatgc
     1021 ttggactaca agtcgccaag tgaatttctt ttgggtggct
//
LOCUS       DAVAZV010000111         1054 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVAZV010000111 DAVAZV010000000
VERSION     DAVAZV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.111"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..555
                     /locus_tag="VQT46_002112"
     CDS             <1..555
                     /locus_tag="VQT46_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2372059.1"
                     /translation="KDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGTE
                     IPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIPA
                     THNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(503..1048)
                     /locus_tag="VQT46_002113"
     CDS             complement(503..1048)
                     /locus_tag="VQT46_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2372060.1"
                     /translation="MNWVVIKIKDIFSINTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT          380 a          165 c          153 g          356 t
ORIGIN      
        1 aaagacgaaa caacctctta tcctatatat gaaatcccag aagcatggag atatattaaa
       61 tttgctagcc tagttaactt cagaatagga aaaactcctc cacgcagtga agctactttt
      121 tggggaactg aaataccttg ggtatctata tcagatatgc ctatatctgg ttatgtaact
      181 aatacgagag aatctatttc taaattagca ttaaaatcaa agaaaataga catttcacct
      241 aaaggaactt tattaatgag ttttaaatta tctattggaa aagttgccat attggatatt
      301 cctgccactc ataatgaagc cattatatcg atattcccct atgctaataa agaaaatatt
      361 atcagagatt acttaatgat atttttgcca cttatctcta ctttaggtga ttcaaaagat
      421 gctataaaag ggaaaacatt aaatagtacc agtatctccg aattattaat ccctatttct
      481 aatcatgaag agatgaaaag aatcatttcc aaagttgatt tactttttca aaaagtttct
      541 caactttttg agtaataagt tcctgttcct caaaaggagc taacggaatt aatagctcgc
      601 ttagtgtagt tttaggaata ttatataaag cttgacctga tagtttagtt attgctttca
      661 attgtttata aaataacgga gaggacaagt taaataatag aaattttgaa ataatctctg
      721 aactttcgaa tggtgttaat tggaaaataa atccaccagc cacaacacca tcatagtctt
      781 tatcgattct tgcaaacttt ccaatatgtt ctaaagaggt tgatacaggt gttattagct
      841 gattatgttt taaataaact tgctcagagg agatgaattg tgtatcaatg tagtaatcat
      901 tatccaacag agaaaattct aaaggcttaa tattaccacc acgtataatt ctaacacctt
      961 tattattaat gcttaaatcg cccttcttgt aagaaagacc tgtatttatt gaaaaaatat
     1021 cttttatttt tataacaacc caattcatag gtat
//
LOCUS       DAVAZV010000112          902 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVAZV010000112 DAVAZV010000000
VERSION     DAVAZV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 902)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 902)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..902
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.112"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            122..590
                     /locus_tag="VQT46_002114"
                     /pseudo
     CDS             122..590
                     /locus_tag="VQT46_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          331 a          135 c          166 g          270 t
ORIGIN      
        1 gagaagagga ttgccatctt ctccattttt atgtgcagag ttatagtggc ttgatgctgg
       61 gaaagtacac tgtgactgct aaaacattcc tagaagctgc tttgatttcc ctaatctatt
      121 tatgcaaatt ttatgttatt ttactataac agttgttgct aagccaaata atagtgggga
      181 agttcattta gacgtaagca ttgaagataa tcagggaggt agtgggtata atttcagttc
      241 tgtttcaagt agctcacaaa cagctaaata tgaaggaact ggttataata acaattcatc
      301 attatatata acgattgata aaacgtctga tgcaacagct cttttgaaat taaagttgaa
      361 taatgttgat aatcaacctg ctactgaagt tcctagttca ggaattactg taaaattaaa
      421 tgctaaagat aatgctggaa actggacaag tgcttcgaat aaagacaagt gcttcgaata
      481 aaaaagaaat aacagtaaaa attgtttctg ctaaaccgac atatccagac aaaatcttag
      541 tgaaaaatcc tgataatata aaagatacag aaaaaaatgc cattattgaa aaattgaaag
      601 aggcaaataa aaatcatcca gcaggagctc caacctttgc taaaggtgaa ggagagcatg
      661 caaatgatat tgtagcaact tattcagatg gtacaactta ttatgtaccg ttaaatgatg
      721 tgacaaaata tgcgaggtag tggctgtacc actcacttat tcacctcccc gtgatttgta
      781 gtagtgatag gctttctcac tattattata aaacaaaata aagatcacaa cactttttca
      841 ttctgtgttg tgccttgagt gaaacgaaag gaatgaatta taaatatgaa aagtatagtc
      901 ac
//
LOCUS       DAVAZV010000113          830 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVAZV010000113 DAVAZV010000000
VERSION     DAVAZV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.113"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            21..830
                     /locus_tag="VQT46_002115"
                     /pseudo
     CDS             21..830
                     /locus_tag="VQT46_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558050.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS1515 family transposase"
BASE COUNT          266 a          174 c          162 g          228 t
ORIGIN      
        1 aaaagtgtta tactattttt atggaaacag tatacgacaa agcacaaaaa cttaactcaa
       61 aaaacttcaa actattgatt ggtgtcaaaa aggaaacctt tcaactcatg ctagaacacc
      121 tgaattcagc ctatcagatt cagcaccgaa aaggtggacg tccacgtagt ctgcccatgg
      181 aagaccagct cattatgacc ctccgttact tgcgatatta tcccactcag cgtctgctgg
      241 cctttgattt tggcgtcggt gtagctacgg taaatgccat catcacttgg gtggaggata
      301 cacttcgtgc gtcaggtagc tttgatttgg accatttaga agccccgagt gctgctgtgg
      361 ctattgacgt gaccgaaagt ccgattcagc gtccaaaaaa aaccaaagca aaaattattc
      421 tggtaaaaag aaacgacaca ccttaaaaac tcaaattatg ctggatttga cgacacataa
      481 agtctgtcaa atggcctttt ctgacggaca tacgcatgat tttactctct tcaaagaaag
      541 tattggacaa agtttgcctg aaacgacgct tgcctttgtt gacctaggtt atttaggcat
      601 cttgaaattt catgagaata ctttcattcc tgctaaaaat tccaaaaatc gccgcctgag
      661 tgaggatgat aagcagttaa ataaagagat gtcagcgata cgaattgaaa ttgaacattt
      721 taacgctaaa ttcaagacct tccaaatcat gtcagtccct tatcgtaacc gcagaaaacg
      781 tttcgagtta cgggcggaat taatttgtgc catcatcaat tatgaagtga
//
LOCUS       DAVAZV010000114          805 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVAZV010000114 DAVAZV010000000
VERSION     DAVAZV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.114"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>805
                     /locus_tag="VQT46_002116"
     CDS             <1..>805
                     /locus_tag="VQT46_002116"
                     /inference="COORDINATES: protein motif:HMM:NF027957.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2372061.1"
                     /translation="PSVSNPGTTNTNTSNNSNTNSQASQSNDIDSLLKQLYKLPLSQR
                     HVESDGLVFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHW
                     VPDSRPEQPSPQSTPEPSPSLQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGV
                     SRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKTYDLLARIHQ
                     DLLDNKGRQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLG"
BASE COUNT          263 a          182 c          156 g          204 t
ORIGIN      
        1 taccttctgt aagcaatcca ggaactacaa atactaacac aagcaacaac agcaacacta
       61 acagtcaagc aagtcaaagt aatgacattg atagtctctt gaaacagctc tacaaactgc
      121 ctttgagtca acgccatgta gaatctgatg gccttgtttt cgacccagcg caaatcacaa
      181 gtcgaaccgc cagaggtgta gctgtccctc atggtaacca ttaccacttt atcccttatg
      241 aacaaatgtc tgaattggaa aaacgaattg ctcgtattat tccccttcgt tatcgttcaa
      301 accattgggt accagattca agaccagaac aaccaagtcc acaatcgact ccggaaccta
      361 gtccaagtct gcaacctgca ccaaatcctc aaccagctcc aagcaatcca attgatgaga
      421 aattggtcaa agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag
      481 tttctcgtta tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca
      541 aactggccaa gcaggaaagt ttatcgcata agctaggagc taagaaaact gacctcccat
      601 ctagtgatag agaattttac aataagactt atgacttact agcaagaatt caccaagatt
      661 tacttgataa taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac
      721 tcaaggatgt ctcaagtgat aaagtcaagt tagtggatga tattcttgcc ttcttagctc
      781 cgattcgtca tccagaacgt ttagg
//
LOCUS       DAVAZV010000115          650 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVAZV010000115 DAVAZV010000000
VERSION     DAVAZV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.115"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            101..265
                     /locus_tag="VQT46_002117"
     CDS             101..265
                     /locus_tag="VQT46_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372062.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            262..>650
                     /locus_tag="VQT46_002118"
     CDS             262..>650
                     /locus_tag="VQT46_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET2372063.1"
                     /translation="MKTFFAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQIIAYIGAVLCLIIMLLLMWGL"
BASE COUNT          184 a          103 c          119 g          244 t
ORIGIN      
        1 atttatgatt tgagtgatcc aaggtcaaaa taagtgctat actagcagtg taaatgttct
       61 tgctcaacta agataaatcg cacatttagg aggaaatctt atgaagaaaa aaatactgat
      121 tattttcgtt ctgtatctaa tcatgtccat ctttctatat ccgcttaggg agagtgcttg
      181 gtatcagcta ttttatacca tagcctatgt gattgcagtt atgatctatt ttgctatcaa
      241 taaaaagaaa ggagaaaaga aatgaaaact ttttttgcta aaaaacggaa catcttcctt
      301 gcgagattgt tcttaggtca gttgcccttg cttgtttcta cttatctatt tctatctcgt
      361 cagtttttaa atttttccgt agttttccaa tttcttttag tagttattaa cttggcttct
      421 attttggtta ctgtttatct cactagggaa atgaggataa gagagtttga agatgatgat
      481 ttggttagtc ctagaaccaa tcaacttatg ttcatcggct tgacaggttt tatgtctatt
      541 atttgtttgt atagaggtat cacagcagga gaatcctacc aacaaataat cgcttatatt
      601 ggcgctgttc tctgcttaat catcatgctt ctgctcatgt ggggcttgaa
//
LOCUS       DAVAZV010000116          611 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVAZV010000116 DAVAZV010000000
VERSION     DAVAZV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..611
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.116"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(189..>611)
                     /locus_tag="VQT46_002119"
     CDS             complement(189..>611)
                     /locus_tag="VQT46_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2372064.1"
                     /translation="KPNEEKPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADN
                     LYKPSTDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAVET
                     LTGLKSSLLLGTKDNNTISAEVDSLLALLKESQPTPIQ"
BASE COUNT          155 a          121 c           93 g          242 t
ORIGIN      
        1 gatgaagttt tttctcaact tcttttactt tattaaatag ttttctaaac cggttattta
       61 accatttaat taaccagtaa atagtttact atttaaaatt acttttgtca agtttctgtt
      121 acgtttttct aaaaaagaga agtaacacga aaggttactt ctccataaaa tatgctccat
      181 tcattttact actgtatagg agtcggttga ctttctttta acaaagccaa gagactatct
      241 acttctgctg aaatagtgtt attatctttc gttccgagaa gaagactact ttttagacca
      301 gtcaatgtct ccacagcatt ttgtctaata ctagaatctg ttactttttc tagcaaggcc
      361 tccgcctctg ctatcttagc gttaataaca gaatgctcta cttgaggaat ttcagcctca
      421 tctgtagtat cttcagcttc ttcctctgtc tcttccgtat cagtgcttgg tttataaaga
      481 ttatctgctg aaggatttaa accagcgtga ttctcttttt catcagattc agggtgagtt
      541 ggctcactta cttcatcatg ttccttatct tcctcaggtt tttctgtctg aggtttctcc
      601 tcgtttggtt t
//
LOCUS       DAVAZV010000117          569 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVAZV010000117 DAVAZV010000000
VERSION     DAVAZV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.117"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>569)
                     /locus_tag="VQT46_002120"
     CDS             complement(<1..>569)
                     /locus_tag="VQT46_002120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372065.1"
                     /translation="AEALVDAEADALVEADSEAEVLAEADALVDAEADALVLAEADAL
                     VDAEADALVLAEAEALVDAEADALVLAEAEALVDAEADALVLAEADALVLAEAEALVD
                     AEAEALVDADSEALVDAEADALIDADSEADVLAEAEALVDAEAEALVDADSEALVDAE
                     AEADVDAEADALVDAEADALVDAEAEALV"
BASE COUNT          137 a          187 c          130 g          115 t
ORIGIN      
        1 tcaaccagcg cctcagcttc agcatcaacg agtgcgtcgg cttcagcatc aacgagtgca
       61 tcggcttcag catcaacgtc tgcctcagct tcagcgtcaa ccagtgcctc tgaatcggca
      121 tcaaccagtg cttcagcctc agcatcgaca agcgcttcgg cttcagcaag tacatcagct
      181 tctgaatctg catcaataag tgcgtcggct tcagcgtcaa ccagtgcctc tgaatcggca
      241 tcaaccagtg cttcagcctc agcatcaacg agtgcttcgg cttcagcaag tacaagtgcg
      301 tcagcttcag caagcacaag tgcgtcagct tcagcatcaa cgagcgcctc ggcttcagca
      361 agcaccagtg cgtcagcttc agcatcaacg agtgcctcgg cctcagcaag tacaagtgcg
      421 tcagcctcag catcaaccag tgcatcagcc tcagcaagta ccagtgcatc agcttccgca
      481 tcaacgagtg catcagcctc agcaagcacc tcagcttctg aatcggcctc aacgagtgcg
      541 tcagcctcag cgtcaacgag tgcttcggc
//
LOCUS       DAVAZV010000118          557 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVAZV010000118 DAVAZV010000000
VERSION     DAVAZV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 557)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 557)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..557
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.118"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            1..377
                     /locus_tag="VQT46_002121"
                     /pseudo
     CDS             1..377
                     /locus_tag="VQT46_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433508.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(412..>557)
                     /locus_tag="VQT46_002122"
     CDS             complement(412..>557)
                     /locus_tag="VQT46_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2372066.1"
                     /translation="KLLPLPPYSPEYNPIEKTWAYIKKNLKKVLPSCNTFYEALFSCS
                     CFN"
BASE COUNT          189 a          115 c           87 g          166 t
ORIGIN      
        1 ctcattcaac aagatagtca gaaactgagt gataaacgat tttatcgccc tacttttcgt
       61 atgcacttga ctaataaaga aattctagat aaacttttga gctattccga agacttgaaa
      121 caccactata atctctatca gctcttgctt ttccacctct gtttcagact ttgtttaaaa
      181 ccttcctcaa agataaagag aaaatcgtca acgcccttca attaccttat tccaacgcca
      241 aactggaagc caccaataat ctcatcaaac ttatcaagca caatgccttt ggttttagga
      301 actttgaaaa cttcaaaaaa gaaaggacga aatttgtcct ttctagatct tcgctttctt
      361 caacccacta cagttgacaa agaaccgaaa aatgtctcgc ctctaatata gtcaattgaa
      421 acaagaacaa gagaaaagag cctcgtaaaa ggtattgcaa cttggtaata cctttttgag
      481 gttctttttg atataagccc atgttttctc aataggattg tactcaggtg agtagggagg
      541 aagaggtaaa agtttat
//
LOCUS       DAVAZV010000119          509 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVAZV010000119 DAVAZV010000000
VERSION     DAVAZV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.119"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>509)
                     /locus_tag="VQT46_002123"
     CDS             complement(<1..>509)
                     /locus_tag="VQT46_002123"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372067.1"
                     /translation="AEALVEADSDALVEADSDAEVLAEAEALVDAEAEALVLAEADAL
                     VLAEAEALVDADSDAEVLAEAEALVLAEADALVDAEAEALVDAEAEALVDADSEADVL
                     AEADALVDADSDALVDAEAEALVDADAEALVLAEADALVLAEAEALVDAEAEALVLAE
                     ADALVEAEA"
BASE COUNT          123 a          168 c          116 g          102 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cctcagcttc agcaagtacc agtgcgtcag cctcagcaag tactagcgcc
      121 tcagcatcag cgtcaacaag tgcttcggct tcagcgtcaa cgagtgcgtc tgagtcagca
      181 tcaacgagtg cgtcagcctc agcaagcaca tcagcttctg aatccgcatc aacaagtgct
      241 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa ccagtgcatc agcttcagca
      301 agtactagcg cctcagcttc agcaagcacc tcagcgtctg aatcggcatc aacgagcgcc
      361 tcagcttcag caagtaccag tgcgtcagcc tcagcaagta ccagtgcttc agcctcagcg
      421 tcgacaagtg cctcggcttc agcaagtacc tcagcgtctg aatcggcctc aaccagtgca
      481 tctgaatcgg cctcaaccag tgcctcagc
//
LOCUS       DAVAZV010000120          497 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVAZV010000120 DAVAZV010000000
VERSION     DAVAZV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..497
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.120"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..497)
                     /locus_tag="VQT46_002124"
                     /pseudo
     CDS             complement(1..497)
                     /locus_tag="VQT46_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          157 a          100 c           96 g          144 t
ORIGIN      
        1 taaaatctct ttattggtta aatgcatacg aaaagtaggg cgataaaaat gtttatcgct
       61 gagtttacga ctatcctgtt gtatgagctt ccagtagcgc ttgatagcct tgtattcatg
      121 agactttcga tccaattgat tcatgatttg aacacgcaca cgactcatag cacggctaag
      181 atgttgtaca atgtgaaagc gatccaacac gattttagca catgggaaaa gttgtctagc
      241 taagtcatag taaggactaa acatatccat agtaataatt ttgacgcgac atcggacggc
      301 tctatcatat ttaagaaagt gatctcggat gacagcttgt gttctaccct caagaacagt
      361 gatgatattg agattgttaa aatcttgcgc aatgaagctc atctccatct cccgattgaa
      421 acagtcactc cccggactgt ttcaacgtcc caagacataa tctcaggcag atttctaaaa
      481 ttacactcaa agtggaa
//
LOCUS       DAVAZV010000121          482 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVAZV010000121 DAVAZV010000000
VERSION     DAVAZV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..482
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.121"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(<1..>482)
                     /locus_tag="VQT46_002125"
     CDS             complement(<1..>482)
                     /locus_tag="VQT46_002125"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET2372068.1"
                     /translation="EALVLAEADALVLAETEALVLAEAEALVDAEAEALVLAEAEALV
                     DADSDAEVLAEAEALVDAEAEALVLAEAEALVLADSDALVDAEAEALVDAEAEALVDA
                     EADALVDAEAEALVDAEAEALVDAEAEALVLAEADALVDAEAEALVLAEADALVEAEA
                     "
BASE COUNT          120 a          161 c          106 g           95 t
ORIGIN      
        1 tcagcttcgg cctcaacaag tgcgtcagct tcagcaagca ccagtgcttc ggcttcagcg
       61 tcgacaagtg cgtcagcctc agcaagcacc agtgcctcag cttcagcatc aacaagtgct
      121 tcagcctcag cgtcaacaag tgcttcagct tcagcatcaa caagtgcgtc agcttcagca
      181 tcaaccagtg cctcagcctc agcgtcgaca agtgcctcgg cttcagcatc gacaagtgca
      241 tctgaatcag caagcacaag tgcttcagct tcagcaagta ccagcgcctc agcctcagca
      301 tcaaccagtg cttcggcttc agcaagtacc tcagcgtctg aatcggcatc aacaagtgct
      361 tcagcttcag caagtacaag cgcctcagct tcagcatcaa ccagtgcttc ggcttcagca
      421 agcaccagtg cctcagtctc agcaagcacc agtgcgtcgg cttcagcaag cacaagcgcc
      481 tc
//
LOCUS       DAVAZV010000122          478 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVAZV010000122 DAVAZV010000000
VERSION     DAVAZV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..478
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.122"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(163..236)
                     /locus_tag="VQT46_002126"
     tRNA            complement(163..236)
                     /locus_tag="VQT46_002126"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(200..202),aa:Asn,seq:gtt)
     gene            complement(242..357)
                     /gene="rrf"
                     /locus_tag="VQT46_002127"
     rRNA            complement(242..357)
                     /gene="rrf"
                     /locus_tag="VQT46_002127"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          146 a          107 c           78 g          147 t
ORIGIN      
        1 ctgttcgctc acaataagag agaacttttt tacgaaaatc tattgaatat gccataaaaa
       61 gattatacca cattgtgtac tatttttggt tcattttact ataacacgaa atagattatt
      121 attacataac aaaaaagagg tctaaacctc ttaactaaat tactccgcca gtaggactcg
      181 aacctacgac atcatgatta acagtcatgc gctactacca actgagctat ggcggattaa
      241 agctaagcga cttccctatc tcacaggggg caacccccaa ctacttccgg cgttctaggg
      301 cttaacttct gtgttcggca tgggtacagg tgtatctcct aggctatcgt cacttaactc
      361 tgagtaatac ctactcaaaa ttgaatatct attcaattca agaaaaccgt tcgctttcat
      421 attctcagtt actttggata agtcctcgag ctattagtat tagtccgcta catgtgtc
//
LOCUS       DAVAZV010000123          476 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVAZV010000123 DAVAZV010000000
VERSION     DAVAZV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.123"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>476
                     /locus_tag="VQT46_002128"
     CDS             <1..>476
                     /locus_tag="VQT46_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2372069.1"
                     /translation="EQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEELLMKDPNY
                     QLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTS
                     TNDGAVAFARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASE"
BASE COUNT          158 a           89 c          106 g          123 t
ORIGIN      
        1 gaacaaatcg tcatcaagat aacagaccaa ggctatgtca cttcacatgg ggaccactat
       61 cattattaca atggtaaggt tccttatgac gctatcatca gtgaagaatt gctgatgaag
      121 gatccaaact accagctaaa ggacgaggat attatcagtg aaatcaaggg tggttatgtg
      181 attaaggtag atggaaaata ctatgtttac cttaaggatg cagctcatgc ggataatgtc
      241 cgtacaaaag aagaaatcaa tcggcaaaaa caagaacata gtcagcatcg tgaaggaggg
      301 acttcaacaa acgatggtgc ggtagccttt gcacgttcac aaggacgcta tactacagat
      361 gatggttata tctttaatgc ttctgatatc attgaggaca cgggtgatgc ttatatcgtt
      421 cctcacggcg accattacca ttacattcct aagaatgagt tatcagctag cgagtt
//
LOCUS       DAVAZV010000124          476 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVAZV010000124 DAVAZV010000000
VERSION     DAVAZV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.124"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>476
                     /locus_tag="VQT46_002129"
     CDS             <1..>476
                     /locus_tag="VQT46_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2372070.1"
                     /translation="EQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEELLMKDPNY
                     KLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHSQHREGGTP
                     RNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKNELSASE"
BASE COUNT          158 a           85 c          104 g          129 t
ORIGIN      
        1 gagcaaatcg tcatcaagat aacagaccaa ggctatgtca cttcacatgg cgaccactat
       61 cattattaca atggtaaggt tccttatgat gcgattttca gtgaagaatt actcatgaaa
      121 gatccaaact ataagctaaa agatgaggat attgttaatg aggtcaaggg tggatatgtt
      181 atcaaggtag atggaaaata ctatgtttac cttaaggatg ctgcccacgc ggataacgtc
      241 cgtacaaaag aggaaatcaa tcgacaaaaa caagaacata gtcaacatcg tgaaggtggg
      301 actccaagaa acgatggtgc tgttgccttg gcacgttcgc aaggacgcta tactacagat
      361 gatggttata tctttaatgc ttctgatatc atagaggata ctggtgatgc ttatatcgtt
      421 cctcatggag atcattacca ttacattcct aagaatgagt tatcagctag cgagtt
//
LOCUS       DAVAZV010000125          393 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVAZV010000125 DAVAZV010000000
VERSION     DAVAZV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.125"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>393
                     /locus_tag="VQT46_002130"
     CDS             <1..>393
                     /locus_tag="VQT46_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET2372071.1"
                     /translation="YLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFR
                     NRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSK
                     EKQEELERVLSNERFRGRQRVLRDLRIVF"
BASE COUNT          143 a           57 c           93 g          100 t
ORIGIN      
        1 taccttcatt tatgggaatt gtcggattgg gaccaagaag gcatgctctg cttacatgaa
       61 ttgattagta gagaagaagg actggtagac gatattccac gtttaaggaa atatttcaaa
      121 accaagtttc gaaatcgaat tttagactat atccgtaagc aggaaagtca gaagcgtaga
      181 tacgataaag aaccctatga agaagtggga gagatcagtc atcgtataag tgaggggggt
      241 ctctggctag atgattatta tctctttcat gaaacactaa gagattatag aaacaaacaa
      301 agtaaagaga aacaagaaga actagaacgc gtcttaagca atgaacgatt tcgagggcgt
      361 caaagagtat taagagactt acgcattgtg ttt
//
LOCUS       DAVAZV010000126          329 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVAZV010000126 DAVAZV010000000
VERSION     DAVAZV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..329
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.126"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(238..325)
                     /locus_tag="VQT46_002131"
     tRNA            complement(238..325)
                     /locus_tag="VQT46_002131"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(289..291),aa:Ser,seq:gct)
BASE COUNT          113 a           67 c           50 g           99 t
ORIGIN      
        1 gcaatgcctt tggttttcga aactttgaaa actttaaaaa acggattttt atcgctttga
       61 acatcaaaaa agaaaggacg aaatttgtcc tttctcgagc ttagcttttc ttcaacccac
      121 tacagttgac aaagagccat aaaaataact tcagattagt aattcaatta agttttacgg
      181 atctgaagct ttattgtctc taaaaataaa aaagagagtt acaaactctc attaaaacgg
      241 agaataaggg attcgaaccc ttgcgccagt tacccgacct aacgatttag caaaccgtcc
      301 tcttcagcct cttgagtaat tctccaatt
//
LOCUS       DAVAZV010000127          310 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVAZV010000127 DAVAZV010000000
VERSION     DAVAZV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.127"
                     /strain="ST1"
                     /db_xref="taxon:1313"
BASE COUNT           87 a           38 c           74 g          111 t
ORIGIN      
        1 cgttgcggta actggagtgc ttttagttgg gaaaattgtt aattcattta aattgtaaac
       61 tttagggatt ctctgaagtt atggatgtcg ttccaatatg tgtacgttgg aatgttagtg
      121 cttatatggg gggaacagaa tcctctcttg attgaagaca agttagccat taggctggtt
      181 tgtctctttg tcaactgtag tgggttgata taatagtatt agtgagtggg ataaaagttt
      241 catttagttt attcagtaca aatttaacgg gtcaagattt attgaactgc accccaatag
      301 ttagacagaa
//
LOCUS       DAVAZV010000128          309 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVAZV010000128 DAVAZV010000000
VERSION     DAVAZV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..309
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.128"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            81..170
                     /locus_tag="VQT46_002132"
     tRNA            81..170
                     /locus_tag="VQT46_002132"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:117..119,aa:Ser,seq:tga)
     gene            184..257
                     /locus_tag="VQT46_002133"
     tRNA            184..257
                     /locus_tag="VQT46_002133"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:218..220,aa:Met,seq:cat)
BASE COUNT           74 a           67 c           85 g           83 t
ORIGIN      
        1 gtgtttagtc cattactagg ggattggaat attatctgtt cactaagagg acacgggctt
       61 gttcccgtat aaactatttt ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
      121 aaccgtcagg cgtgtaaaag cgtgcgtggg ttcgaatccc acatcctcct tttatattat
      181 taacgcggga tggagcagct cggtagctcg tcgggctcat aacccgaagg tcgtaggttc
      241 aaatcctgct cccgcaataa ggctcggtag ctcagttggt agagcaatgg attgaagctc
      301 catgtgtcg
//
LOCUS       DAVAZV010000129          299 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVAZV010000129 DAVAZV010000000
VERSION     DAVAZV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.129"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..223
                     /locus_tag="VQT46_002134"
     CDS             <1..223
                     /locus_tag="VQT46_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET2372072.1"
                     /translation="QAQTPRKSSKLKPLTAEDKACNHVLSKERSKVENIFAKVKTLKM
                     FSTTYRNHRKRFGLRMNLIVGIINHELGF"
BASE COUNT          109 a           52 c           54 g           84 t
ORIGIN      
        1 tcaagcacaa actccacgta aatccagcaa actcaagccg ctaacagctg aagataaagc
       61 ctgtaaccat gtgctatcta aggagagaag caaggttgag aacatctttg ccaaagtaaa
      121 aacgcttaaa atgttttcaa caacctatcg aaatcatcgt aaacgcttcg gattacggat
      181 gaatttgatt gttggtatta tcaatcatga actaggattc tagttttgca ggaagtctat
      241 tatcaaaaat accatcagga ttatataaga ttgatacagg aaaagtttta ttttatggt
//
LOCUS       DAVAZV010000130          292 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVAZV010000130 DAVAZV010000000
VERSION     DAVAZV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.130"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            51..>292
                     /locus_tag="VQT46_002135"
     rRNA            51..>292
                     /locus_tag="VQT46_002135"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           90 a           54 c           81 g           67 t
ORIGIN      
        1 gaaaaaaaca ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga
       61 gtttgatcct ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct
      121 gaaggaggag cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct
      181 gcctggtagc gggggataac tattggaaac gatagctaat accgcataag agtagatgtt
      241 gcatgacatt tgcttaaaag gtgcacttgc atcactacca gatggacctg cg
//
LOCUS       DAVAZV010000131          288 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVAZV010000131 DAVAZV010000000
VERSION     DAVAZV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.131"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>288
                     /locus_tag="VQT46_002136"
     CDS             <1..>288
                     /locus_tag="VQT46_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HET2372073.1"
                     /translation="NRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEW
                     FDEGLYEAPKGYTLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNG"
BASE COUNT           93 a           59 c           59 g           77 t
ORIGIN      
        1 caaccgcgtg aaagcagcta agaaggtgcc acttgatcgt atgccttaca atcttcaata
       61 tactgtagaa gtcaaaaacg gtagtttaat catacctcat tatgaccatt accataacat
      121 caaatttgag tggtttgacg aaggccttta tgaggcacct aaggggtata ctcttgagga
      181 tcttttggcg actgtcaagt actatgtcga acatccaaac gaacgtccgc attcagataa
      241 tggttttggt aacgctagcg accatgttca aagaaacaaa aatggtca
//
LOCUS       DAVAZV010000132          277 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVAZV010000132 DAVAZV010000000
VERSION     DAVAZV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..277
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.132"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>277
                     /locus_tag="VQT46_002137"
     CDS             <1..>277
                     /locus_tag="VQT46_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET2372074.1"
                     /translation="QRIIEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAM
                     QGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQG"
BASE COUNT          126 a           37 c           47 g           67 t
ORIGIN      
        1 aacaacgcat aatagaagca atcgaatcag ctttagaaaa agtagatgaa tatgctgaaa
       61 gttataatag actagaacag ctagataaag aatttccaga taaactaaaa aaatctattc
      121 ttcaatatgc tatgcaagga aaattagttg aacaagaccc aaatgatgaa tcagtcgaag
      181 ttttacttga aaaaatacga gcagaaaaac aaaaactctt tgaagaaggc aagattaaaa
      241 agaaagattt ggacatttct attgtttccc aaggaga
//
LOCUS       DAVAZV010000133          272 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVAZV010000133 DAVAZV010000000
VERSION     DAVAZV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.133"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            complement(1..272)
                     /locus_tag="VQT46_002138"
                     /pseudo
     CDS             complement(1..272)
                     /locus_tag="VQT46_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT           75 a           72 c           48 g           77 t
ORIGIN      
        1 atacttgagg ctgtattcaa ttgcccttcc tagttttgaa cccgataaaa ctgactgacg
       61 ccggcaccaa gcaaagaaat cttccattag gttggagctc ttcttgacgt ttctgtagtc
      121 gttcatcagc tggcaaagcc tcccagtctc tttccaagaa aaataactga tcacaataag
      181 ctaaaccttt agctcctaag gatgatttat ccgcttgctt gggggtcgct tcaaaaaact
      241 tccttctcac atgcgcccaa catccaacaa gt
//
LOCUS       DAVAZV010000134          229 bp    DNA     linear   BCT 10-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain ST1
            SAMEA2064490-rid20177123.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVAZV010000134 DAVAZV010000000
VERSION     DAVAZV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA2064490
            Sequence Read Archive: ERR351823
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001980447.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001980447.1
            Genome Coverage       :: 167x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 00:12:52
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,139
            CDSs (total)                      :: 2,100
            Genes (coding)                    :: 1,959
            CDSs (with protein)               :: 1,959
            Genes (RNA)                       :: 39
            rRNAs                             :: 2, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 23S)
            partial rRNAs                     :: 2 (16S)
            tRNAs                             :: 31
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 141
            CDSs (without protein)            :: 141
            Pseudo Genes (ambiguous residues) :: 0 of 141
            Pseudo Genes (frameshifted)       :: 66 of 141
            Pseudo Genes (incomplete)         :: 72 of 141
            Pseudo Genes (internal stop)      :: 36 of 141
            Pseudo Genes (multiple problems)  :: 27 of 141
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..229
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA2064490-rid20177123.denovo.134"
                     /strain="ST1"
                     /db_xref="taxon:1313"
     gene            <1..>229
                     /locus_tag="VQT46_002139"
     CDS             <1..>229
                     /locus_tag="VQT46_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET2372075.1"
                     /translation="YTDDEIQVAKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHS
                     HWIKKDSLSEAERAAAQAYAKEKGLTPPSTDH"
BASE COUNT           72 a           49 c           55 g           53 t
ORIGIN      
        1 tacactgatg atgagattca agtagccaag ttggcaggca agtacacaac agaagacggt
       61 tatatctttg atcctcgtga tataaccagt gatgaggggg atgcctatgt aactccacat
      121 atgacccata gccactggat taaaaaagat agtttgtctg aagctgagag agcggcagcc
      181 caggcttatg ctaaagagaa aggtttgacc cctccttcga cagaccatc
//
